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1. Gopalakrishnan R, Simonton S, Rohrer MD, Koutlas IG: Cystic variant of calcifying epithelial odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Dec;102(6):773-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic variant of calcifying epithelial odontogenic tumor.
  • Calcifying epithelial odontogenic tumor (CEOT) is a benign, locally aggressive odontogenic neoplasm characterized by sheets and nests of epithelial cells with deeply eosinophilic or occasionally clear cytoplasm, calcifications, and eosinophilic amorphous material that stains positive for amyloid.
  • It deformed the medial wall, the inferior orbital floor, and caused narrowing of the left inferior meatus.

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  • (PMID = 17138180.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Kiralj A, Ilić M, Markov B, Dedić S, Pejaković B, Nalić B: [Chondroma of the skull base and maxilla]. Med Pregl; 2007 Nov-Dec;60(11-12):649-51
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  • INTRODUCTION: Chondromas are uncommon benign tumors of cartilaginous origin.
  • A chondroma is a painless, slow growing tumor causing destruction and exfoliation of teeth.
  • On a radiograph, the tumor appears as a cyst-like radiolucent lesion, while some are sclerotic.
  • DISCUSSION AND CONCLUSION: Chondromyxoid fibroma (CMF) is a rare, benign cartilaginous tumor that often occurs in the metaphyses of proximal tibia, proximal and distal femur and small bones of the foot.
  • The differential diagnosis is wide and includes simple or aneyrismal bone cyst, giant cell tumor, nonossifying fibroma, fibrous dysplasia, enchondroma, chondroblastoma, eosinophilic granuloma and fibrous cortical defect.
  • Our case demonstrates an uncommon occurrence in the maxillary sinus: CMF with nasal, pterygoid and orbital infiltration.
  • In the diagnosis of an intracranial chondrocytic tumor, it is important to distinguish it from enchondroma and chondrosarcoma.
  • The present case underlines the importance of MR examination in the diagnosis of soft tissue masses in the craniofacial region.

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  • (PMID = 18666612.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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3. Viswanathan S, George S, Ramadwar M, Shet T, Arora B, Laskar S, Qureshi S, Medhi S, Muckaden MA, Kurkure PA, Kane SV, Banavali S: Extraconal orbital tumors in children--a spectrum. Virchows Arch; 2009 Jun;454(6):703-13
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  • [Title] Extraconal orbital tumors in children--a spectrum.
  • Orbital masses in children are uncommon but extremely challenging problems for clinicians and pathologists due to their critical location and availability of limited diagnostic material.
  • We analyzed 47 specimens comprising biopsies, excision specimens, and FNAC of extraconal pediatric orbital masses (excluding retinoblastoma) accessioned in the pathology department over 5 years in a tertiary referral cancer center.
  • Malignant round cell tumors (76.6%), chiefly embryonal rhabdomyosarcoma (51%), benign spindle cell neoplasms, and infectious lesions (tuberculosis, fungal infections), were seen.
  • Of the malignant tumors, those confined to the orbit achieved good treatment response and had an event-free follow-up while those with extraorbital spread had poor outcome.
  • Pediatric orbital masses range from completely treatable infectious lesions, surgically resectable benign neoplasms to aggressive malignancies requiring chemotherapy and radiotherapy.
  • [MeSH-major] Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Algorithms. Biomarkers, Tumor / analysis. Child. Child, Preschool. Exophthalmos / diagnosis. Female. Humans. Infant. Male. Mycoses / diagnosis. Mycoses / therapy. Rhabdomyosarcoma, Embryonal / chemistry. Rhabdomyosarcoma, Embryonal / diagnosis. Rhabdomyosarcoma, Embryonal / secondary. Tuberculosis / diagnosis. Tuberculosis / therapy

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  • (PMID = 19421774.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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4. Amoli FA, Mehrabani PM, Tari AS: Aggressive orbital optic nerve meningioma with benign microscopic features: a case report. Orbit; 2007 Dec;26(4):271-4
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  • [Title] Aggressive orbital optic nerve meningioma with benign microscopic features: a case report.
  • Here we report the case of a 20-year-old female with an aggressive orbital meningioma referred to the Ophthalmology Department of the Farabi Hospital in Tehran.
  • The patient had a history of orbital meningioma from 10 years ago and several surgical resections due to tumor recurrence during these 10 years.
  • On admission, the patient had a large orbital mass and severe proptosis.
  • MRI images revealed a large left orbital mass with optic nerve involvement and extension to the left maxillary sinus, pterygoid fossa and the dura in the floor of the anterior fossa.
  • Fine-needle aspiration cytology of the mass confirmed tumor recurrence.
  • The patient first received radiotherapy due to the inoperable mass, and the tumor was resected 1.5 month later.
  • The interesting aspect of this case was the aggressive behavior of the tumor with intraocular invasion, despite its benign histopathological features, which led to wide exenteration of the eye together with resection of the upper and lower lids.
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasm Recurrence, Local

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  • (PMID = 18097966.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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5. Looi A, Kazim M, Cortes M, Rootman J: Orbital reconstruction after eyelid- and conjunctiva-sparing orbital exenteration. Ophthal Plast Reconstr Surg; 2006 Jan-Feb;22(1):1-6
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  • [Title] Orbital reconstruction after eyelid- and conjunctiva-sparing orbital exenteration.
  • PURPOSE: To describe the technique and results of eyelid- and conjunctiva-sparing orbital exenteration with temporalis transfer and dermis-fat graft.
  • The remaining four cases retained orbital volume and eyelid structures with a reasonable cosmetic outcome.
  • CONCLUSIONS: Eyelid- and conjunctiva-sparing orbital exenteration with temporalis transfer and dermis-fat graft is a useful technique that minimizes the usual deformity and achieves good results.
  • Case selection is emphasized, as this technique is mainly reserved for histopathologically benign orbital lesions that exhibit local aggressive behavior and for malignant lesions only if there is no eyelid, lacrimal gland, or orbital fissure involvement nor significant conjunctival or deep extension of an intraocular tumor.
  • [MeSH-major] Conjunctiva / surgery. Eyelids / surgery. Orbit Evisceration. Reconstructive Surgical Procedures / methods. Surgical Flaps

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  • (PMID = 16418657.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Kawamoto S, Matsuda H, Ueki K, Okada Y, Kim P: Neuromuscular choristoma of the oculomotor nerve: case report. Neurosurgery; 2007 Apr;60(4):E777-8; discussion E778
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Neuromuscular choristomas (NMC) are rare benign tumors of the peripheral nerves.
  • CLINICAL PRESENTATION: An 18-year-old girl presented with long-standing intermittent retro-orbital pain and oculomotor paresis.
  • INTERVENTION: The tumor was resected with the parental oculomotor nerve, which was reconstructed using a peroneal nerve graft.
  • Histologically, the lesion consisted of well-differentiated smooth muscle fibers intermingled with mature nerve elements consistent with the diagnosis of an NMC, although the possibility of leiomyoma in this rare location was not excluded completely.
  • CONCLUSION: NMC may need histological confirmation for diagnosis if they occur in the intracranial space.

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  • (PMID = 17415185.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Brovkina AF, Tadzhieva ZA, Sherstnev VV: [Clinical and epidemiological study of lacrimal neoplasms]. Vestn Oftalmol; 2009 May-Jun;125(3):3-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A cross-sectional mass epidemiological survey of 18,320 urban and rural citizens of the Republic of Tadjikistan revealed 31 patients with orbital tumors, of which lacrimal neoplasms were determined in 4 (0.022% in the general population and 12.9% of the identified orbital tumors).
  • According to the referral data, the prevalence of lacrimal neoplasms was 1.03% of all the tumors of the organ of vision and 5.26% of the orbital neoplasms.
  • Epithelial tumors were more common (52%), their malignant forms dominated over benign ones (55.7% versus 44.3%).
  • With the higher grade of anaplasia, the likelihood of a recurrence of a tumor and the rate of its growth increased (r = +0.83).
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Morbidity. Population Surveillance. Retrospective Studies. Tajikistan / epidemiology

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  • (PMID = 19566038.001).
  • [ISSN] 0042-465X
  • [Journal-full-title] Vestnik oftalmologii
  • [ISO-abbreviation] Vestn Oftalmol
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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8. Aitasalo KM, Peltola MJ: Bioactive glass hydroxyapatite in fronto-orbital defect reconstruction. Plast Reconstr Surg; 2007 Dec;120(7):1963-72; discussion 1973-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bioactive glass hydroxyapatite in fronto-orbital defect reconstruction.
  • METHODS: In a retrospective series of 150 patients, 62 patients underwent reconstruction with frontal sinus obliteration after chronic frontal sinusitis, 65 patients were operated on for fronto-orbital traumas, and 23 patients underwent reconstruction after fronto-orbital tumor resections.
  • In fronto-orbital reconstructions, we have reoperated on the orbital floor in four cases (7 percent).
  • All 12 benign tumor patients and six of 11 malignant tumor patients survived during a follow-up of 3 years.
  • Two of the 23 (9 percent) complicated tumor and trauma patients underwent reoperation because of a local mucocele.
  • The reconstructions with bioactive glass and hydroxyapatite are associated with good functional and aesthetic results without donor-site morbidity.
  • [MeSH-major] Bone Substitutes. Durapatite. Frontal Bone / surgery. Glass. Orbit / surgery. Reconstructive Surgical Procedures / instrumentation
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Frontal Sinus / surgery. Frontal Sinusitis / surgery. Humans. Male. Materials Testing. Middle Aged. Mucocele / surgery. Orbital Neoplasms / surgery. Recurrence. Retrospective Studies. Skull Neoplasms / surgery

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  • Hazardous Substances Data Bank. HYDROXYAPATITE .
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  • (PMID = 18090760.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Substitutes; 91D9GV0Z28 / Durapatite
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9. Charles NC, Lisman RD, Lelli GJ Jr: Subperiosteal orbital fibroma. Ophthalmic Surg Lasers Imaging; 2008 Nov-Dec;39(6):517-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subperiosteal orbital fibroma.
  • A patient noting a slowly enlarging bump at the orbital rim underwent surgical excision of the lesion.
  • Pathologic examination showed a benign fibroma, a lesion that to the authors' knowledge has never been previously reported in this location.
  • [MeSH-major] Fibroma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Female. Humans. Neoplasm Proteins / analysis

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  • (PMID = 19065988.001).
  • [ISSN] 1542-8877
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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10. Madani G, Beale TJ, Lund VJ: Imaging of sinonasal tumors. Semin Ultrasound CT MR; 2009 Feb;30(1):25-38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This article reviews the role of imaging in the diagnosis of sinonasal tumors, illustrating the diversity of tumors affecting this region.
  • The symptoms of sinonasal tumors are nonspecific; imaging plays a critical role in distinguishing benign and malignant disease and may occasionally illustrate characteristic radiological features of specific tumors.
  • Critical imaging review areas are discussed together with accurate staging, including orbital and intracranial involvement, which determine the appropriate surgical approach.
  • The sites and patterns of tumor recurrence and the imaging features of recurrent tumor are also discussed.
  • [MeSH-major] Magnetic Resonance Imaging. Nose Neoplasms / diagnosis. Paranasal Sinuses. Tomography, X-Ray Computed

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  • (PMID = 19388236.001).
  • [ISSN] 0887-2171
  • [Journal-full-title] Seminars in ultrasound, CT, and MR
  • [ISO-abbreviation] Semin. Ultrasound CT MR
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 48
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11. Składzień J, Tomik J, Wiatr M: [Primary benign orbital tumors in experience of the Department of Otolaryngology Jagiellonian University]. Przegl Lek; 2006;63(11):1210-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary benign orbital tumors in experience of the Department of Otolaryngology Jagiellonian University].
  • THE AIM OF THE STUDY: It was assessment of the data of primary non malignant tumor therapy in Cracovian Department of Otolaryngology.
  • In 118 cases primary benign orbital tumors were removed, in remaining patients tumors were malignant.
  • [MeSH-major] Ophthalmologic Surgical Procedures. Orbital Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Hospitals, University. Humans. Infant. Middle Aged. Orbit / surgery. Orbit Evisceration / methods. Otolaryngology. Retrospective Studies. Treatment Outcome

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  • (PMID = 17348418.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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12. Hodges JM, McDevitt AS, El-Sayed Ali AI, Sebelik ME: Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations. Indian J Otolaryngol Head Neck Surg; 2010 Sep;62(3):236-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Juvenile angiofibroma (JNA) is a relatively uncommon, highly vascular and benign tumor that presents most commonly in adolescent males.
  • In addition to these symptoms, up to one-third of patients with this condition may present with proptosis or other orbital involvement, which are late symptoms and findings.Most physicians agree that surgery is the primary treatment modality for the early-stage disease process.

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  • (PMID = 23120720.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450247
  • [Keywords] NOTNLM ; Angiofibroma / Cyberknife / Embolization / Endoscopic surgery / IMRT / Image guided robotic radiotherapy / Skull base / Vascular tumor
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13. Sterker I, Hagert-Winkler A, Gradistanac T, Frerich B: [Granular cell tumor of the orbit]. Ophthalmologe; 2007 Sep;104(9):803-5
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  • [Title] [Granular cell tumor of the orbit].
  • [Transliterated title] Granularzelltumor der Orbita.
  • Granular cell tumor (GCT, Abrikossoff tumor) is an extremely rare, benign tumor with a neurogenic origin occurring most commonly in the upper aerodigestive tract.
  • GCT of the orbit is a rarity, representing a diagnostic and therapeutic challenge.
  • We report on a 26 year old man suffering from unilateral ocular hypertension and retrobulbar pain.
  • The surgical removal of the GCT, extending into the orbital apex, was performed by an interdisciplinary team using a combination of "midfacial degloving" and LeFort I-osteotomy.
  • [MeSH-major] Granular Cell Tumor. Orbital Neoplasms
  • [MeSH-minor] Adult. Biopsy. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Orbit / pathology. Osteotomy. Time Factors. Treatment Outcome

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  • (PMID = 17440732.001).
  • [ISSN] 0941-293X
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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14. Decock CE, Kataria S, Breusegem CM, Van Den Broecke CM, Claerhout IJ: Ectopic meningioma anterior to the lacrimal gland fossa. Ophthal Plast Reconstr Surg; 2009 Jan-Feb;25(1):57-9
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  • A 66-year-old man reported a slowly growing tumor on the lateral edge of his left upper eyelid.
  • A neoplasm of the lacrimal gland was suspected.
  • Resection of the tumor was performed, which was located just behind the orbital septum and in front of the lacrimal gland.
  • Anatomopathologic investigation of the excised specimen with immunohistochemistry revealed a benign meningioma of a meningotheliomatous type, containing multiple bone elements.
  • An ectopic orbital meningioma is rare, and this is the first case of a unique lateral localization of this lesion.
  • Therefore, it should be included in the differential diagnosis of a lacrimal gland tumor.
  • [MeSH-major] Choristoma / radiography. Lacrimal Apparatus / radiography. Meningeal Neoplasms. Meningioma. Orbital Neoplasms / radiography

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  • (PMID = 19273931.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucin-1; 0 / Vimentin
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15. Durig JS, Klainguti G: [Treatment of a complication after surgical removal of an aneurysmal cyst of the ethmoid]. Klin Monbl Augenheilkd; 2005 Mar;222(3):234-7
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  • [Transliterated title] Kyste Anevrismal de l'Ethmoide: Traitement d'une Complication Post-Operatoire.
  • INTRODUCTION: An aneurysmal cyst (AC) is a rare benign bony tumor with a possible aggressive extension.
  • CLINICAL HISTORY AND FINDINGS: A 40-year-old man with a left ethmoidal AC extending to the orbital roof underwent 2 surgeries.
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Reoperation. Tomography, X-Ray Computed. Vision, Binocular / physiology

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  • (PMID = 15785988.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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16. Zimmermann AP, Eivazi B, Wiegand S, Werner JA, Teymoortash A: Orbital lymphatic malformation showing the symptoms of orbital complications of acute rhinosinusitis in children: a report of 2 cases. Int J Pediatr Otorhinolaryngol; 2009 Oct;73(10):1480-3
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  • [Title] Orbital lymphatic malformation showing the symptoms of orbital complications of acute rhinosinusitis in children: a report of 2 cases.
  • Orbital lymphatic malformations are benign cystic malformations of the lymphatic system.
  • The present report shows two cases with symptoms of orbital complications of acute rhinosinusitis with proptosis, compressive optic neuropathy, loss of vision and cellulites in children.
  • A tumor extirpation was performed via lateral orbitotomy in both cases.
  • Histological analysis of the surgical specimens verified lymphatic malformations of the orbit.
  • Orbital lymphatic malformations can mimic the symptoms of orbital complications of acute rhinosinusitis.
  • The existence of lymphatic malformation should be considered in every orbital complication of rhinosinusitis in children.
  • [MeSH-major] Lymphatic Abnormalities / pathology. Orbital Diseases / pathology. Rhinitis / pathology. Sinusitis / pathology
  • [MeSH-minor] Acute Disease. Adolescent. Anti-Bacterial Agents / therapeutic use. Biopsy, Needle. Child, Preschool. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging / methods. Male. Orbital Neoplasms / diagnosis. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Risk Assessment. Severity of Illness Index. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 19646769.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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17. Currie ZI, Rose GE: Long-term risk of recurrence after intact excision of pleomorphic adenomas of the lacrimal gland. Arch Ophthalmol; 2007 Dec;125(12):1643-6
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  • METHODS: Medical records were reviewed for 133 patients and only those patients with 5 years or more of follow up were classified into the following 5 subgroups: those with intact excision (group IA, n = 46), those with surgically intact excision but areas of complete attenuation of the pseudocapsule at histologic analysis (group IB, n = 7), those with previous inadvertent incisional biopsy (group IIA, n = 9), those with breach of the pseudocapsule during attempted intact excision (group IIB, n = 5), and those undergoing definitive surgery because of tumor recurrence after previous incomplete excision (group III, n = 5).
  • RESULTS: Seventy-two patients were followed up longer than 5 years; there were no known tumor recurrences among 61 patients excluded with shorter follow-up.
  • Patients in groups IA and IB exhibited no tumor recurrences at 8.2 to 34.1 years of follow-up.
  • A benign recurrence occurred along the superior orbital fissure in 1 patient in group IIA 12(1/2) years after the initial surgery and was resected.
  • Long-term follow-up is, however, necessary when there has been tumor disruption, either inadvertently during previous biopsy or by capsular breach during definitive excision.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Lacrimal Apparatus Diseases / pathology. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 18071115.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Lessell S, Kim JW, Hatton MP, Stemmer-Rachamimov A, Thiagalingham S, Rubin PA: Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma. J Neuroophthalmol; 2007 Jun;27(2):104-6
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  • A 28-year-old man with a biopsy-proven benign intraorbital optic nerve sheath meningioma developed recurrent clinical manifestations of ipsilateral retrobulbar inflammation 9 years after undergoing postoperative radiation therapy.
  • Debulking of the tumor 11 years after the original surgery again revealed no pathologic signs of inflammation.
  • Whether growth of tumor, surgery, radiation, or edema triggered the inflammatory manifestations is unclear.
  • Our case affirms that primary optic nerve meningiomas may rarely cause episodic manifestations resembling those of idiopathic orbital inflammation that resolve with corticosteroid treatment.

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  • (PMID = 17548993.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Khademi B, Taraghi A, Mohammadianpanah M: Anatomical and histopathological profile of head and neck neoplasms in Persian pediatric and adolescent population. Int J Pediatr Otorhinolaryngol; 2009 Sep;73(9):1249-53
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  • Orbital and skin tumors and neoplasms with secondary (metastatic) involvement of the head and neck were excluded from the study.
  • Based on the data obtained from a tertiary referral hospital tumor registry and oncology department, a total of 152 benign and malignant neoplasms of the head and neck in patients aged 19 years or younger (99 boys), whom were reported to this institution between 2000 and 2007, were analyzed in this study.
  • There were 136 (89.5%) malignant tumors and 16 (10.5%) benign neoplasms.
  • CONCLUSION: The most frequent primary site, malignant histopathological type, and male-female ratio in our study were comparable with other reported series; however, the ratio of benign to malignant lesions is different from most studies.

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  • (PMID = 19525017.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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20. Romer M, Bode B, Schuknecht B, Schmid S, Holzmann D: Solitary fibrous tumor of the orbit--two cases and a review of the literature. Eur Arch Otorhinolaryngol; 2005 Feb;262(2):81-8
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  • [Title] Solitary fibrous tumor of the orbit--two cases and a review of the literature.
  • Solitary fibrous tumors of the orbit (SFT) are mesenchymal lesions that can develop either as malignant or benign neoplasias.
  • We describe the histological features leading to the diagnosis in two females and review the current literature.
  • Diagnosis of SFT only can be performed by histological examination, since clinical signs and radiological features are not specific enough.
  • Even a malignant or benign course cannot be predicted, since clinical and radiological features do not correlate with histological signs of malignancy and vice versa.
  • [MeSH-major] Neoplasms, Fibrous Tissue / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 15316820.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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21. Schulze S, Hoerle S, Koop G, Barth PJ, Huegens-Penzel M, Strempel I: Intravascular papillary endothelial hyperplasia - a rare finding in the orbital region. Ophthalmologica; 2008;222(3):213-5
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  • [Title] Intravascular papillary endothelial hyperplasia - a rare finding in the orbital region.
  • Intravascular papillary endothelial hyperplasia is a benign lesion of vascular origin.
  • We report the case of a 58-year-old woman sent to our clinic for surgery of an orbital fat prolapse at her right eye.
  • The clinical examination showed a displacable swelling with a slightly livid aspect approximately 2 cm in diameter under the upper orbital rim.
  • After MRI, a biopsy was carried out leading to the histological diagnosis of intravascular papillary endothelial hyperplasia.
  • The complete excision of the remaining tumor was performed 8 weeks later.
  • We discuss this clinical entity and the management of such lesions in the orbital region.
  • [MeSH-major] Endothelium, Vascular / pathology. Orbital Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Hyperplasia. Magnetic Resonance Imaging. Middle Aged. Ophthalmologic Surgical Procedures / methods

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  • [Copyright] (c) 2008 S. Karger AG, Basel
  • (PMID = 18497532.001).
  • [ISSN] 1423-0267
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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22. El Kohen A, Lahlou M, Rabeh G, Benjelloun A, Lazrak A, Jazouli N, Kzadri M: [Orbital osteoma: clinical evaluation of nine cases]. Rev Stomatol Chir Maxillofac; 2005 Feb;106(1):7-12
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  • [Title] [Orbital osteoma: clinical evaluation of nine cases].
  • [Transliterated title] Les ostéomes orbitaires: évaluation clinique de neuf cas.
  • MATERIAL AND METHODS: Nine patients (five men and four women), mean age 24.3 years (18-43) presenting orbital osteoma were managed from 1994 to 1999.
  • The bony orbital tumefaction was located in the superior medial angle in five patients.
  • Radiography (Blondeau view) demonstrated an opacity in the sinus with an orbital extension.
  • DISCUSSION: Frontoethmoidal osteoma is a relatively rare benign tumor.
  • Severity depends on the orbital and endocranial extension.
  • Imaging provides the positive diagnosis and guides the surgical approach.
  • Therapeutic indications depend on the tumor size, its course, and the development of complications.
  • [MeSH-major] Orbital Neoplasms / surgery. Osteoma / surgery
  • [MeSH-minor] Adolescent. Adult. Diplopia / etiology. Ethmoid Sinus / surgery. Exophthalmos / etiology. Female. Follow-Up Studies. Frontal Sinus / surgery. Humans. Male. Maxillary Sinus / surgery. Nasal Obstruction / etiology. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / surgery. Postoperative Complications. Sinusitis / etiology. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15798645.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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23. Robinson JW, Brownstein S, Jordan DR, Hodge WG: Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature. Surv Ophthalmol; 2006 Sep-Oct;51(5):513-9
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  • [Title] Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature.
  • Invasive mucoepidermoid carcinoma of the conjunctiva of the left lower eyelid was diagnosed in an orbital exenteration specimen of a 57-year-old woman, after a biopsy of the same lesion was originally diagnosed as invasive squamous cell carcinoma.
  • The woman was undergoing mitomycin C injections for ocular cicatricial pemphigoid, diagnosed in the same eye 2 years prior to identification of the neoplasm.
  • The tumor invaded the cornea, sclera, lacrimal gland, regional small nerves, and lymphatics, but did not show intraocular involvement.
  • [MeSH-major] Carcinoma, Mucoepidermoid / pathology. Conjunctival Neoplasms / pathology. Conjunctivitis / complications. Pemphigoid, Benign Mucous Membrane / complications
  • [MeSH-minor] Basement Membrane / pathology. Biopsy. Drug Therapy, Combination. Female. Fluorometholone / therapeutic use. Humans. Middle Aged. Mitomycin / therapeutic use. Neoplasm Invasiveness. Ofloxacin / therapeutic use


24. Wang HY, Fan QH, Gong QX, Wang Z: [Clinicopathologic characteristics of hemangiopericytoma/solitary fibrous tumor with giant cells]. Zhonghua Bing Li Xue Za Zhi; 2009 Mar;38(3):169-72
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  • [Title] [Clinicopathologic characteristics of hemangiopericytoma/solitary fibrous tumor with giant cells].
  • OBJECTIVE: To study the pathological characteristics, diagnosis and differential diagnoses of hemangiopericytoma-solitary fibrous tumor with giant cells.
  • METHODS: Pathological characteristics of seven cases of orbital and extraorbital hemangiopericytoma-solitary fibrous tumors with giant cells were evaluated by HE and immunohistochemistry (EnVision method).
  • RESULTS: Two cases were located in the orbit, one of which had recurred.
  • Seven patients underwent tumor excision and were well and without tumor recurrence upon the clinical follow-up.
  • CONCLUSIONS: Hemangiopericytoma-solitary fibrous tumor with giant cells is an intermediate soft tissue tumor.
  • It typically involves the orbital or extraorbital regions.
  • Histologically, the tumor should be distinguished from giant cell fibroblastoma, pleomorphic hyalinzing angiectatic tumor of soft part and angiomatoid fibrous histiocytoma.
  • [MeSH-major] Hemangiopericytoma / pathology. Orbital Neoplasms / pathology. Solitary Fibrous Tumors / pathology
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Antigens, CD34 / metabolism. Cell Adhesion Molecules / metabolism. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Female. Follow-Up Studies. Histiocytoma, Benign Fibrous / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local. Proto-Oncogene Proteins c-bcl-2 / metabolism. Soft Tissue Neoplasms / pathology. Solitary Fibrous Tumor, Pleural / metabolism. Solitary Fibrous Tumor, Pleural / pathology. Solitary Fibrous Tumor, Pleural / surgery. Young Adult

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  • (PMID = 19575851.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Proto-Oncogene Proteins c-bcl-2
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25. Kreusel KM: Ophthalmological manifestations in VHL and NF 1: pathological and diagnostic implications. Fam Cancer; 2005;4(1):43-7
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  • Von Hippel-Lindau disease (VHL) and neurofibromatosis type 1 (NF 1) are hereditary multitumor syndromes that show associated ocular manifestations.
  • Capillary retinal angioma, a benign vascular tumor, is the classical ocular lesion in VHL.
  • It often appears as the first manifestation of the disease and may thus lead to the diagnosis of VHL.
  • Since small angiomas can be treated easily by laser photocoagulation, a regular ocular screening of VHL patients is recommended.
  • Ocular manifestations of NF 1 are more diverse as compared to VHL.
  • Extension of the tumor beyond the chiasm worsens the prognosis quoad vitam.
  • The rare intraorbital pexiform neurofibroma is associated with abnormal development of the orbital bones and infantile glaucoma.
  • It may result in orbital mass effects and therefore may need surgical excision.
  • [MeSH-major] Hemangioma / etiology. Neurofibromatosis 1 / complications. Neurofibromatosis 1 / diagnosis. Optic Nerve Glioma / etiology. Retinal Neoplasms / etiology. von Hippel-Lindau Disease / complications. von Hippel-Lindau Disease / diagnosis

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  • (PMID = 15883709.001).
  • [ISSN] 1389-9600
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 63
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26. Guthikonda B, Hanna EY, Skoracki RJ, Prabhu SS: Ameloblastic fibrosarcoma involving the anterior and middle skull base with intradural extension. J Craniofac Surg; 2009 Nov;20(6):2087-90
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  • Ameloblastic fibrosarcoma is a malignant odontogenic tumor that rarely affects the skull base and surrounding regions.
  • We present a case of a 48-year-old man with histologically confirmed malignant transformation of a benign ameloblastic fibroma 10 years after initial presentation of a localized facial mass.
  • The ameloblastic fibrosarcoma extended from the facial region to the orbit, anterior and middle fossa skull base, the infratemporal fossa, and the cavernous sinus.
  • Thus, vigilant long-term follow-up is essential despite the benign nature of the initial pathologic lesion.
  • [MeSH-minor] Cavernous Sinus / pathology. Cranial Fossa, Anterior / pathology. Cranial Fossa, Anterior / surgery. Cranial Fossa, Middle / pathology. Cranial Fossa, Middle / surgery. Cranial Nerve Neoplasms / pathology. Cranial Nerve Neoplasms / surgery. Facial Neoplasms / pathology. Facial Neoplasms / surgery. Humans. Male. Middle Aged. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Radiotherapy, Adjuvant. Surgical Flaps

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  • (PMID = 19884826.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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27. Sieśkiewicz A, Łysoń T, Obuchowska I, Napora K, Rogowski M, Turek G, Mariak Z: [Endoscopic surgery of the orbit]. Klin Oczna; 2010;112(10-12):350-5
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  • [Title] [Endoscopic surgery of the orbit].
  • The aim of the study was to present, basing on own experience, the virtues and limitations of endoscopic transnasal surgery in the diagnosis and treatment of orbital pathologies.
  • This article contains a review of endoscopic treatment of lacrimal duct stenosis, evacuation of inflammatory lesions and benign tumors penetrating the orbit from the adjacent sinuses, management of primary intraorbital tumors, Graves-Basedov orbitopathy and posttraumatic lesions of the optic nerves.
  • Both own experience and data from the relevant literature indicate that intraorbital inflammatory lesions can nowadays be effectively treated by means of endoscopy whereas purely endoscopic removal of intraorbital tumor still remains rare because is technically demanding and requires high experience in this type of surgery.
  • [MeSH-major] Dacryocystorhinostomy. Endoscopy / methods. Orbit / surgery. Orbital Neoplasms / surgery
  • [MeSH-minor] Constriction, Pathologic / surgery. Humans. Lacrimal Duct Obstruction / diagnosis. Surgery, Computer-Assisted. Surgical Flaps. Visual Acuity

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  • (PMID = 21473090.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
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28. Wilde F, Neid M, Schulz T, Sterker I, Hemprich A, Frerich B: [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases]. Mund Kiefer Gesichtschir; 2005 Nov;9(6):404-8
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  • [Title] [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases].
  • [Transliterated title] Hämangioperizytom (extrapleuraler solitärer fibröser Tumor). Dargestellt und diskutiert anhand zweier Patientenbeispiele.
  • It is a very uncommon potentially malignant vascular tumour which can occur at every site of the body.
  • The diagnosis of "hemangiopericytoma" is now only determined if a constant histological picture of hemangiopericytoma is present.
  • The tumour can lead to lymphogenous or hematogenous metastasis.
  • CASE REPORTS: Patient 1: 60 years, female; diagnosis: malignant suboccipital hemangiopericytoma; size: 4.9 x 4.5 x 4.2 cm; pT1bNXMX L0 V0 Pn0; stage IA; grading G1; R0.Patient 2: 38 years, male; diagnosis: benign hemangiopericytoma infraorbital left; size 1.5 x 1.5 x 1.5 cm.
  • The slow and painless growth carries the danger of a clinically wrong diagnosis and thus delayed therapy.
  • The histological diagnosis of hemangiopericytoma is determined by biopsy.
  • The therapy of choice is the complete tumour-resection with a safety margin of 1 cm.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangiopericytoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Orbit / pathology. Orbital Neoplasms / diagnosis. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 16220316.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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29. Kim HJ, Shields CL, Eagle RC Jr, Shields JA: Fibrous histiocytoma of the conjunctiva. Am J Ophthalmol; 2006 Dec;142(6):1036-43
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  • The tumor was present for a mean of three months (median, five months; range, one to 12 months) and was unilateral (one right eye, five left eyes).
  • In all cases, the tumor was a tan, dome-shaped limbal mass in the conjunctival stroma with visible intrinsic vessels.
  • The mean tumor basal dimension was 7 mm (median, 5 mm; range, 4 to 11 mm).
  • Surgical resection was performed in all cases, and histopathologic study demonstrated benign FH in four cases and malignant FH in two cases.
  • Those cases with benign FH showed no recurrence over nine months (median, eight months; range, three to 18 months).
  • There was no evidence of orbital invasion or remote metastasis in any case over the mean follow-up period of 21 months (median, 10 months; range, three to 80 months).
  • CONCLUSION: FH is a rare conjunctival tumor that can show benign or malignant features.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Child. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17157587.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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30. Krásný J, Sach J, Brunnerová R, Konvicka J, Jankovská M, Srp A, Kozák J: [Orbital tumors in adults--a 10-year study]. Cesk Slov Oftalmol; 2008 Nov;64(6):219-27
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  • [Title] [Orbital tumors in adults--a 10-year study].
  • The authors refer about diagnostic procedures, treatment and follow-up of 87 adult patients with orbital tumors during the period 1998 - 2007 in the Department of Ophthalmology, Faculty Hospital Královské Vinohrady, Charles University, Prague, Czech Republic, E.U.
  • In 49 patients, the tumors were of benign origin (age 18-80 years, median, 48 years), and 38 patients suffered from malign tumors (age 38-89 years, median, 61 years).
  • Among basic examinations methods ranked the magnetic resonance imaging and the histological verification of the tumor.
  • The anterior diagnostic or therapeutic orbitotomy was used in 72.5% of the cases, lateral osteoplastic orbitotomy (Kronlein) in 14.5%, and exenteration of the orbit in 13% of the cases.
  • Altogether 23 patients were treated without surgery by means of corticosteroids, or are followed-up due to a benign tumor only.
  • As the most common, the inflammatory pseudotumors of the orbit were diagnosed in 40%.
  • Clinically they were of the anterior nodular, or posterior diffuse form, dacryoadenitis or orbital myositis.
  • In four cases the sarcoidosis was established.The second tumor in the final ranking was lymphoma in 19.5%; the MALT-lymphoma was diagnosed in 59% of these cases.
  • Both these tumors, counting the same number as lymphomas, were the only indications to the exenteration of the orbit, and causes of the death in four patients.
  • CONCLUSION: Among orbital tumors in adults, the most common were inflammatory pseudotumor and lymphoma.
  • [MeSH-major] Orbital Neoplasms

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  • (PMID = 19110961.001).
  • [ISSN] 1211-9059
  • [Journal-full-title] Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti
  • [ISO-abbreviation] Cesk Slov Oftalmol
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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31. Percodani J, Rose X, Vergez S, Pessey JJ, Serrano E: [Endonasal endoscopic approach in the treatment of sino-nasal inverted papillomas]. Ann Otolaryngol Chir Cervicofac; 2006 Dec;123(6):312-8
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  • INTRODUCTION: Sino-nasal inverted papilloma is a rare benign tumor of the nasal fossa and the paranasal sinuses for which the successful surgical treatment by an endonasal approach has been corroborated in the literature.
  • Fourteen patients were operated using a combined approach, associating either a vestibular (9 cases), a paralateral nasal (3 cases) or a fronto-orbital (2 cases) approach with endonsal endoscopy.
  • CONCLUSIONS: Endoscopic endonasal surgery is a validated surgical approach for the treatment of sino-nasal inverted papilloma in that total tumor removal is possible.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors

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  • (PMID = 17202989.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] France
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32. Schmack I, Patel RM, Folpe AL, Wojno T, Zaldivar RA, Balzer B, Kang SJ, Weiss SW, Grossniklaus HE: Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. Am J Surg Pathol; 2007 Feb;31(2):193-8
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  • [Title] Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor.
  • Prolapse of subconjunctival intraconal orbital fat is a rare cause of an intraorbital mass lesion.
  • Over the past several years, we have seen a number of cases in which this prolapsed fat was confused pathologically with a neoplasm of adipocytic lineage, specifically pleomorphic lipoma and atypical lipomatous neoplasm (well-differentiated liposarcoma).
  • We report the clinical, histopathologic, and immunohistochemical findings in 21 specimens from 17 patients, all of whom presented with prolapsed intraconal orbital fat.
  • Subconjunctival prolapsed orbital fat was localized in the superotemporal quadrant or lateral canthus around the rectus muscle below the lacrimal gland.
  • "Control" sections of normal orbital fat showed occasional Lochkern cells but lacked floret cells.
  • We conclude that subconjunctival herniated orbital fat commonly contains multinucleated floretlike giant cells, fibrous septae, and Lochkern cells, features that may result in diagnostic confusion with pleomorphic lipoma and atypical lipomatous neoplasms.
  • Importantly, specific diagnostic features, such as aggregates of bland spindled cells associated with wiry collagen, as seen in pleomorphic lipoma, and enlarged hyperchromatic cells within fibrous septae, as in atypical lipomatous neoplasms, are entirely absent in herniated orbital fat.
  • Multinucleated floret cells present in prolapsed orbital fat likely represent a reactive phenomenon, as they are not present in normal orbital fat.
  • [MeSH-major] Adipose Tissue / pathology. Conjunctiva / pathology. Conjunctival Diseases / pathology. Eye Neoplasms / diagnosis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbit / pathology
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adult. Aged. Aged, 80 and over. Biomarkers / metabolism. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prolapse. Tomography, X-Ray Computed

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  • (PMID = 17255763.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30-EY06360
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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33. Dave SP, Bared A, Casiano RR: Surgical outcomes and safety of transnasal endoscopic resection for anterior skull tumors. Otolaryngol Head Neck Surg; 2007 Jun;136(6):920-7
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  • There were 17 malignant and two benign lesions.
  • It should be noted that the tumor control rate may be premature given the small sample size and limited follow-up.
  • Overall, there were 16 complications, but only two of these, an orbital hematoma and a frontal lobe abscess, were considered major complications directly attributable to surgery.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Survival Rate

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  • (PMID = 17547980.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Khong JJ, Chen CS, James CL, Huilgol SC, O'Donnell BA, Sullivan TJ, Selva D: Malignant fibrous histiocytoma of the eyelid: differential diagnosis and management. Ophthal Plast Reconstr Surg; 2005 Mar;21(2):103-8
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  • [Title] Malignant fibrous histiocytoma of the eyelid: differential diagnosis and management.
  • The purpose of this study was to present a case series of periocular MFH and to discuss the differential diagnosis and management.
  • Local recurrence occurred in 3 cases, and of these, 1 required orbital exenteration.
  • There were no distant metastases or tumor-related deaths.
  • CONCLUSIONS: This study highlights the difficulties in the clinicopathologic diagnosis of periocular MFH and in particular the distinction of more superficial tumors from atypical fibroxanthoma.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Eyelid Neoplasms / surgery. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Combined Modality Therapy. Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Male. Neoplasm Recurrence, Local. Ophthalmologic Surgical Procedures. Radiotherapy, Adjuvant. Retrospective Studies

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  • (PMID = 15778662.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Lieb WE: [Tumors and tumor-like lesions of the orbit]. HNO; 2010 Jul;58(7):661-71
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  • [Title] [Tumors and tumor-like lesions of the orbit].
  • [Transliterated title] Tumoren und tumorähnliche Läsionen der Orbita.
  • This article gives an overview of the most common and clinically relevant tumors of the orbit and their treatment.
  • The most common orbital tumors in childhood are cystic tumors, such as dermoid and epidermoid cysts.
  • Capillary hemangiomas are the most common primary benign tumors of the orbit and appear mostly in the first year of life.
  • In contrast teratomas are rare and histologically mostly benign.
  • Rhabdomyosarcoma is a rapidly growing malignant orbital tumor whereby the stage and localization are the most important prognostic factors for survival chance in children.
  • Secondary tumors of the orbit are often manifested in the nose and paranasal sinuses.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / therapy

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  • (PMID = 20607507.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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36. Peltola M, Kinnunen I, Aitasalo K: Reconstruction of orbital wall defects with bioactive glass plates. J Oral Maxillofac Surg; 2008 Apr;66(4):639-46
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  • [Title] Reconstruction of orbital wall defects with bioactive glass plates.
  • This study evaluated the clinical outcome of bioactive glass plates in reconstructive orbital surgery.
  • PATIENTS AND METHODS: In a retrospective series of 49 patients, 35 orbital floors and 6 orbital medial and superior walls were reconstructed after fronto-orbital trauma, and 8 patients were treated with BAG plates after fronto-orbital tumor resection.
  • RESULTS: During the 2-year follow-up, 3 of the 35 orbital floor trauma reconstructions were reoperated (9%) because of diplopia, and new reconstructions with BAG were performed.
  • In all of the 8 patients with tumors and in 6 of the patients undergoing orbital wall reconstruction, the plates were in the correct position after reconstruction, and none had to be removed.
  • One patient with a benign tumor and 7 of the 8 patients with malignant tumors survived to the 2-year follow-up.
  • CONCLUSIONS: Reconstructive surgery of the orbit is one of the most demanding challenges in head and neck surgery.
  • In orbital defect reconstruction, a BAG plate seems to be a well-tolerated and reliable reconstruction material alternative; however, BAG plates are brittle and rigid, and cannot be molded and shaped by a surgeon.
  • [MeSH-major] Bone Substitutes. Fracture Fixation, Internal / methods. Glass. Orbit / surgery. Orbital Fractures / surgery. Orbital Implants. Orbital Neoplasms / surgery

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  • (PMID = 18355587.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Substitutes; 0 / bioactive glass S53P4
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37. Orzechowska-Wylegała B, Jedrzejewski P, Wylegała E, Steplewska K: Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report. Klin Oczna; 2008;110(7-9):301-3
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  • [Title] Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report.
  • Benign pleomorphic adenoma (mixed tumor) is the most frequently occurring tumor of epithelial origin.
  • In 1996, a 35 year old male patient underwent surgery to remove a tumor of the left orbit.
  • In 2005, from a cut along the upper-outer edge of the left orbit, an elastic and soft tumor 1 cm in diameter was removed from soft tissues of the upper eyelid.
  • Then, with the use of the side orbitotomy technique, the orbit was opened through incision of the temporal muscle and removal of the orbital side wall.
  • An eyelid nodule of 0.8 mm in diameter was removed together with an elastic and hard tumor of size 2.5 x 1 cm.
  • The result of the histopathological examination of the palpebral tumor was pseudocystic tumor and of the orbital tumor was pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Lacrimal Apparatus / pathology. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery

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  • (PMID = 19112866.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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38. Fernandes BF, Castiglione E, Belfort RN, Codère F, Burnier MN Jr: Orbital leiomyoma: histopathologic and immunohistochemical findings of a rare tumor. Ophthal Plast Reconstr Surg; 2009 Jan-Feb;25(1):59-61
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  • [Title] Orbital leiomyoma: histopathologic and immunohistochemical findings of a rare tumor.
  • A 51-year-old man was referred for evaluation of a right orbital hemangioma.
  • The tumor did not compromise other orbital structures.
  • On the basis of the histopathologic and immunohistochemical findings, the diagnosis of orbital leiomyoma was established.
  • Orbital leiomyoma is a slow-growing tumor that can be located anywhere in the orbit.
  • Although there are no unique features that help the radiologist to exclude other benign lesions of the orbit, the histopathologic diagnosis using immunohistochemical markers is usually straightforward.
  • Attention to the cytologic features that exclude the malignant variant is of utmost relevance for proper diagnosis and patient counseling.
  • [MeSH-major] Leiomyoma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunoenzyme Techniques. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19273932.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Cerdá-Nicolás M, Löpez-Gines C, Gil-Benso R, Benito R, Pellin A, Ruiz-Saurí A, Sanchos-Garcia J, Roldan P, Talamantes F, Barberá J: Solitary fibrous tumor of the orbit: morphological, cytogenetic and molecular features. Neuropathology; 2006 Dec;26(6):557-63
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  • [Title] Solitary fibrous tumor of the orbit: morphological, cytogenetic and molecular features.
  • Solitary fibrous tumor (SFT), a benign neoplasm arising in mesenchymal structures, was initially described in the pleura but subsequently has also been documented in other locations.
  • It is uncommon in the orbit, where it closely resembles other benign spindle-shaped mesenchymal tumors of this area such as schwannoma, meningioma or hemangiopericytoma.
  • We present a case of orbital SFT in a 34-year-old woman.
  • Measurement of DNA content revealed a DNA index of 1, indicating a diploid peak in 95% of the tumor cells.
  • No p14(ARF), p15(INK4B) and p16(INK4A) deletions or hypermethylation were observed in this benign tumor.
  • Following surgical resection and radiotherapy, the patient showed no tumor relapse after one year of follow-up.
  • [MeSH-major] Fibroma / genetics. Fibroma / pathology. Orbital Neoplasms / genetics. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Cyclin-Dependent Kinase Inhibitor p15 / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. DNA Methylation. Exons / genetics. Female. Gene Deletion. Genes, p53 / genetics. Humans. Magnetic Resonance Imaging. Point Mutation. Proto-Oncogene Proteins c-mdm2 / genetics. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology. Tumor Suppressor Protein p14ARF / genetics

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  • (PMID = 17203593.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p15; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p14ARF; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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40. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20
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  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • On radiologic examination, the mass was seen to extend into the anterior orbit.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.
  • It is important to consider it preoperatively because the vascular nature of this tumour may create problems with hemostasis during excision.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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41. Nuruddin M, Osmani M, Mudhar HS, Fernando M: Orbital lipofibromatosis in a child: a case report. Orbit; 2010 Dec;29(6):360-2
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  • [Title] Orbital lipofibromatosis in a child: a case report.
  • PURPOSE: Lipofibromatosis is a rare, benign, soft tissue tumor that typically involves extremities particularly in children.
  • We report a young girl with lipofibromatosis involving the superotemporal quadrant of the left orbit.
  • CASE REPORT: An 8-year-old girl presented with a history of a gradually expanding mass in the superotemporal quadrant of the left orbit over several years.
  • Orbital imaging showed a soft tissue mass superolateral to the globe with possible infiltration into the lacrimal gland and lateral rectus muscle.
  • Histopathological examination revealed that the lesion consisted of adipose tissue with fibroblastic elements, being consistent with a diagnosis of lipofibromatosis.
  • COMMENT: Orbital involvement of lipofibromatosis as reported here is indeed a very rare entity.
  • Diagnosis can be confirmed by histopathological analysis.
  • [MeSH-major] Fibroma / pathology. Lipoma / pathology. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery
  • [MeSH-minor] Biopsy, Needle. Blepharoptosis / diagnosis. Blepharoptosis / etiology. Child. Female. Follow-Up Studies. Humans. Immunohistochemistry. Ophthalmologic Surgical Procedures / methods. Rare Diseases. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 21158580.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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42. Liarakos VS, Ilari L, Chalvatzis N, Papaparaskeva K, Mavrikakis I: Isolated orbital fibrous dysplasia associated with ipsilateral keratoconus. Orbit; 2010 Jun;29(3):154-7
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  • [Title] Isolated orbital fibrous dysplasia associated with ipsilateral keratoconus.
  • INTRODUCTION: Fibrous dysplasia is a primary orbital bone tumor, described as a benign disorder in which proliferation of fibrous tissue and osteoid replaces and distorts the bone from which it derives.
  • High resolution corneal topography confirmed unilateral keratoconus and a CT scan showed an ovoid mass with a well defined sclerotic margin arising from the left ethmoid sinus and invading the orbit.
  • [MeSH-major] Fibrous Dysplasia of Bone / diagnosis. Fibrous Dysplasia of Bone / surgery. Keratoconus / diagnosis. Keratoconus / surgery. Orbit / pathology
  • [MeSH-minor] Biopsy, Needle. Ethmoid Sinus / pathology. Ethmoid Sinus / surgery. Exophthalmos / diagnosis. Exophthalmos / etiology. Follow-Up Studies. Humans. Immunohistochemistry. Lacrimal Apparatus Diseases / diagnosis. Lacrimal Apparatus Diseases / etiology. Male. Rare Diseases. Risk Assessment. Tomography, X-Ray Computed / methods. Treatment Outcome. Vision Disorders / diagnosis. Vision Disorders / etiology. Young Adult

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  • (PMID = 20497083.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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43. Park YK, Kim EJ, Kim SW: Osteoblastoma of the ethmoid sinus. Skeletal Radiol; 2007 May;36(5):463-7
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  • An osteoblastoma is a benign bone tumor that most often occurs in the vertebral column and the long bones of the extremities.
  • CT demonstrated an expansile, lesion of the right ethmoid sinus, which caused the orbital contents to be compressed and deviated to the right.
  • [MeSH-major] Ethmoid Sinus / pathology. Ethmoid Sinus / surgery. Osteoblastoma / diagnosis. Osteoblastoma / surgery. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 17265159.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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44. Livaoĝlu M, Cakir E, Karaçal N: Large orbital osteoma arising from orbital roof: Excision through an upper blepharoplasty incision. Orbit; 2009;28(2-3):200-2
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  • [Title] Large orbital osteoma arising from orbital roof: Excision through an upper blepharoplasty incision.
  • Osteoma is the most common benign tumor of facial bony structure.
  • We report a case of intraorbital, pedicled osteoma originating from the left orbital roof.
  • There were not any postoperative complications and all ocular symptoms in the left eye were resolved after 1 month.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / surgery. Osteoma / diagnosis. Osteoma / surgery
  • [MeSH-minor] Biopsy, Needle. Blepharoplasty / methods. Blepharoptosis / diagnosis. Blepharoptosis / etiology. Follow-Up Studies. Humans. Imaging, Three-Dimensional. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Ophthalmologic Surgical Procedures / methods. Risk Assessment. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19839914.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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45. De Oliveira Junior PA, Moreira A, Brum M, Chaves A, Santos FA, Groppo FC: Modified surgical approach for removal of an ivory osteoma in the paranasal sinus. A case report. Minerva Stomatol; 2008 Mar;57(3):127-31
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  • Osteomas are benign tumors that consist mainly of mature compact or cancellous bone.
  • The most common site in maxillofacial complex is the mandible, particularly the angle, followed by sinuses.
  • The ethmoid and orbital portions were approached and excised through a Weber-Ferguson incision and maxillary osteotomy was carried out to remove the ivory osteoma, considering its location in the central and deep region of the face.
  • After tumor removal and drainage of frontal and ethmoidal sinuses, the bone flap was repositioned using titanium microplates and screws.

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  • (PMID = 18427381.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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46. Kinoshita S, Kakizaki H, Iwaki M, Hara K: [Two cases of dermolipoma]. Nippon Ganka Gakkai Zasshi; 2007 Dec;111(12):965-9
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  • BACKGROUND: Dermolipoma is an uncommon benign tumor, congenitally occurring on the conjunctiva, and may be present at other sites.
  • The appearance of dermolipoma closely resembles orbital fat prolapse and limbal dermoid, and therefore it is necessary to take this into account in diagnosis.
  • CASE REPORT: The first case was a 52-year-old female patient referred for the treatment of an orbital fat prolapse in her right eye.
  • Another case, an 8-year-old female patient, was referred for the treatment of a bulbar conjunctival tumor in her left eye.
  • In both cases, dermolipoma was suspected because the tumor did not show in the limbus and it did not change in size even when the eyeball was pressed.
  • CONCLUSIONS: If the special features of dermolipoma are understood, it is easy to distinguish this tumor from other disorders.

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  • (PMID = 18186219.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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47. Burduk PK, Seredyka-Burduk M, Olejarz E: [Giant tumor of the orbit--a case of hidradenoma]. Otolaryngol Pol; 2007;61(6):1017-20
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  • [Title] [Giant tumor of the orbit--a case of hidradenoma].
  • Orbital tumors are very differential group of lesions.
  • More often a benign lesions is found than malignant.
  • We present a case of 62 years old man with large expansion of benign tumor of the orbit with exophthalmus, eye movement disability and complete blindness.
  • The authors performed radical surgery with removing of the orbit content.
  • Histopathology described a very rare tumor of the orbit-hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Orbital Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 18546956.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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48. Vijayalakshmi P, Jethani J, Kim U: Congenital unilateral ocular fibrosis syndrome secondary to benign congenital tumor. Indian J Ophthalmol; 2006 Jun;54(2):123-5
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  • [Title] Congenital unilateral ocular fibrosis syndrome secondary to benign congenital tumor.
  • Prenatal orbital penetration has been proposed as a cause of this syndrome.
  • We report a case of this rare syndrome associated with an adjacent sinus tumor.
  • [MeSH-major] Oculomotor Muscles / pathology. Orbital Neoplasms / complications
  • [MeSH-minor] Diagnosis, Differential. Female. Fibrosis / congenital. Fibrosis / etiology. Fibrosis / pathology. Humans. Infant. Magnetic Resonance Imaging

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  • (PMID = 16770032.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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49. Benatiya Andaloussi I, Touiza E, Bhallil S, Oudidi A, Bouayed MA, Daoudi K, El Alami MN, Tahri H: Orbital osteoma: three case reports. Bull Soc Belge Ophtalmol; 2006;(300):73-9
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  • [Title] Orbital osteoma: three case reports.
  • INTRODUCTION: Osteoma is the most frequent benign tumor of paranasal sinuses.
  • Three cases with orbital extension are reported and discussed.
  • OBSERVATIONS: 1st observation: Mrs. M.N. is an 18 years-old caucasian female who presented a stony orbital deformity associated with chronical dacryocystitis.
  • Tomography of the orbit revealed a probable ethmoidal osteoma compressing the lacrimal canals.
  • The management consisted in a surgical excision of the whole tumor by external approach, associated with a dacryocystorhinostomy.
  • The tumor was removed through an external ethmoidectomy.
  • The computed tomography is of a great contribution, not only for diagnosis but also for the choice of the surgical approach.
  • This surgery may induce ocular or neurochirurgical complications.
  • If they become voluminous, they may cause orbital manifestations and serious complications.
  • The rarity of ethmoidal osteoma with orbital growth made our cases interesting to report.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Osteoma / diagnosis

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  • (PMID = 16903514.001).
  • [ISSN] 0081-0746
  • [Journal-full-title] Bulletin de la Société belge d'ophtalmologie
  • [ISO-abbreviation] Bull Soc Belge Ophtalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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50. Arkha Y, Benazzou S, Harmouch A, Derraz S, El Ouahabi A, El Khamlichi A: [A case of cystic craniofacial fibrous dysplasia]. Rev Stomatol Chir Maxillofac; 2010 Apr;111(2):101-4
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  • [Transliterated title] Un cas de dysplasie fibreuse kystique craniofaciale.
  • INTRODUCTION: Fibrous dysplasia is a benign, idiopathic, fibro-osseous disease.
  • Computed tomography and magnetic resonance imaging of the head revealed an extensive cystic tumor of the left fronto-ethmoido-sphenoidal region, with compression of the left frontal lobe and medial orbital wall.
  • Histology proves the diagnosis.
  • [MeSH-minor] Adolescent. Craniotomy. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Mucocele / diagnosis

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  • [CommentIn] Rev Stomatol Chir Maxillofac. 2010 Sep;111(4):244-6 [20656311.001]
  • (PMID = 20359731.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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51. Tang DR, Shi XF, Sun FY, Zhao H, Jin YJ: [Clinical features and therapy of benign lymphoepithelial lesion]. Zhonghua Yan Ke Za Zhi; 2009 May;45(5):441-5
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  • [Title] [Clinical features and therapy of benign lymphoepithelial lesion].
  • OBJECTIVE: To report the clinical features of benign lymphoepithelial lesion and to further characterize recommendations for its therapy strategy.
  • Retrospective analyze the clinical characteristics, imaging features, pathological manifestation and the treatment effect from the clinical materials of 9 cases of patients with benign lymphoepithelial lesion presenting to Tianjin Eye Hospital from Jan 2006 to Dec 2007.
  • RESULTS: The 9 cases, in which 7 cases were female, 7 cases had lesions on both eyes, demonstrated unpainful swelling of the lacrimal glands and in different degree of salivary glands or had history of tumor resection of salivary glands.
  • Orbital CT scanning showed increased homogeneous density with clear boundary in the lacrimal gland area.
  • Three patients were operated to excise the lacrimal gland masses due to imperfect treatment effect of medication or in order to make definite diagnosis.
  • The postoperative pathological results supported the diagnosis of benign lymphoepithelial lesion.
  • CONCLUSIONS: A clinical condition with swelling of either or both lacrimal gland and of any salivary gland, and accompanied with systemic relative diseases should be considered benign lymphoepithelial lesion.
  • Imaging examinations are helpful to definite diagnosis.
  • The definite diagnosis should be made through pathological examinations.
  • [MeSH-major] Mikulicz' Disease / diagnosis. Mikulicz' Disease / drug therapy

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  • (PMID = 19576068.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glucocorticoids
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52. Meli GA, Meli L, Chiaramonte R, Riva G, Pero G: Osteoblastoma of the orbit. A case report and review of the literature. Neuroradiol J; 2008 Feb 18;21(1):71-6
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  • [Title] Osteoblastoma of the orbit. A case report and review of the literature.
  • We describe a case of benign orbital tumour involving the frontal sinus and ethmoidal cells.
  • CT findings were typical of "bone tumour of the orbit", histological analysis yielded a diagnosis of benign osteoblastoma.
  • The orbit is rarely involved by bone tumours, but all bone tumours may theoretically involve the orbit, often making it difficult to establish the right differential diagnosis by imaging.
  • Even though many literature reports suggest CT is the landmark in bone tumour diagnosis, we think it should always be accompanied by MRI.
  • MRI is known to overestimate local staging, but its contribution to differential diagnosis among various tumours may be decisive.

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  • (PMID = 24256752.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Khong JJ, Moore S, Prabhakaran VC, Selva D: Genetic testing in orbital tumors. Orbit; 2009;28(2-3):88-97
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  • [Title] Genetic testing in orbital tumors.
  • OBJECTIVE: This review aims to discuss the clinical application of cytogenetic and molecular testing in the diagnosis and prognosis of orbital tumors and, in so doing, highlight the basis of these methods, their advantages, and limitations.
  • SUMMARY: Specific chromosomal aberrations are detected in many lymphoproliferative neoplasms, soft tissue tumors, and in a few benign tumors of the orbit.
  • Detection of these characteristic chromosomal translocations is most helpful to refine the diagnosis and classification, especially when the tumor is poorly differentiated and shows overlapping morphological features with another tumor type.
  • This review outlines orbital tumors with characteristic chromosomal translocations and the relative frequency of detecting the genetic mutation.
  • [MeSH-major] Genetic Testing / methods. Lymphoproliferative Disorders / genetics. Orbital Neoplasms / genetics. Soft Tissue Neoplasms / genetics

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  • (PMID = 19839890.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 86
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54. Miyamoto J, Tatsuzawa K, Owada K, Kawabe T, Sasajima H, Mineura K: Usefulness and limitations of fluorine-18-fluorodeoxyglucose positron emission tomography for the detection of malignancy of orbital tumors. Neurol Med Chir (Tokyo); 2008;48(11):495-9; discussion 499
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  • [Title] Usefulness and limitations of fluorine-18-fluorodeoxyglucose positron emission tomography for the detection of malignancy of orbital tumors.
  • Fluorine-18-fluorodeoxyglucose positron emission tomography ([18F]FDG PET) was assessed as a method for providing information about the malignancy of orbital tumors.
  • Twelve patients with 13 orbital tumors underwent [18F]FDG PET followed by biopsy or tumor removal via a transcranial approach.
  • The accumulation ratio between the tumor and the contralateral normal tissue (T/N ratio) was calculated for 10 of the 13 lesions.
  • The T/N ratio in benign lesions was compared with that in malignant tumors.
  • The T/N ratio was 1.06 +/- 0.03 (mean +/- standard deviation) in benign tumors, and significantly higher at 1.81 +/- 0.27 in malignant tumors (p = 0.0027).
  • Both patterns of high and iso uptake of [18F]FDG were found in orbital pseudotumor.
  • [18F]FDG PET can determine the malignancy of orbital tumors, but cannot distinguish malignant tumor from inflammatory disease such as pseudotumor.
  • [MeSH-major] Optic Nerve Neoplasms / radionuclide imaging. Orbital Neoplasms / radionuclide imaging. Positron-Emission Tomography
  • [MeSH-minor] Adenocarcinoma / radionuclide imaging. Adolescent. Adult. Aged. Astrocytoma / radionuclide imaging. Carcinoma, Adenoid Cystic / radionuclide imaging. Diagnosis, Differential. Female. Fluorine Radioisotopes. Fluorodeoxyglucose F18. Glioblastoma / radionuclide imaging. Hemangioma, Cavernous, Central Nervous System / radionuclide imaging. Humans. Lymphoma, B-Cell, Marginal Zone / radionuclide imaging. Male. Melanoma / radionuclide imaging. Middle Aged. Neurilemmoma / radionuclide imaging. Orbital Pseudotumor / radionuclide imaging. Radiopharmaceuticals. Young Adult

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  • (PMID = 19029776.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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55. Schlimper C, Sommer T, Flacke S, Wolff M, Schild H, Kreft B: [Radiologic features of inflammatory pseudotumors]. Rofo; 2005 Nov;177(11):1506-12
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  • Inflammatory pseudotumor is a rare benign tumor entity.
  • Inflammatory pseudotumor most commonly involves the lung and the orbit, but it has been reported to occur in nearly every site in the body.
  • For making a definite diagnosis a biopsy is often essential.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Heart Diseases / diagnosis. Heart Diseases / radiography. Humans. Liver Diseases / diagnosis. Liver Diseases / radiography. Magnetic Resonance Imaging. Male. Orbital Pseudotumor / diagnosis. Orbital Pseudotumor / radiography. Plasma Cell Granuloma, Pulmonary / diagnosis. Plasma Cell Granuloma, Pulmonary / radiography. Radiography, Abdominal. Radiography, Thoracic. Splenic Diseases / diagnosis. Splenic Diseases / radiography. Tomography, X-Ray Computed

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  • (PMID = 16302131.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 54
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56. Giudice C, Marco R, Mirko R, Luca M, Giorgio C: Zygomatic gland adenoma in a dog: histochemical and immunohistochemical evaluation. Vet Ophthalmol; 2005 Jan-Feb;8(1):13-6
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  • Orbital epithelial tumors in dogs are rare and most frequently malignant.
  • Distinguishing their origin from the lacrimal or zygomatic gland is often challenging and is based mostly on tumor location.
  • A case of adenoma involving the orbit in a 13-year-old, female, standard Schnauzer is reported.
  • Histologically, the neoplasm was characterized by nests and cords of epithelial cells mostly forming small glandular structures.
  • The origin of the tumor from the zygomatic gland was determined by histochemical characteristics (alcian blue pH 1 positive staining) of a small remnant of normal gland included within the tumor capsule.
  • The benign nature of our finding was confirmed by follow-up information: 2 years after complete surgical removal of the mass no tumor recurrence or metastases was recorded.
  • [MeSH-major] Adenoma / veterinary. Dog Diseases / diagnosis. Lacrimal Apparatus. Orbital Neoplasms / veterinary
  • [MeSH-minor] Animals. Diagnosis, Differential. Dogs. Female. Immunohistochemistry / veterinary

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  • (PMID = 15644095.001).
  • [ISSN] 1463-5216
  • [Journal-full-title] Veterinary ophthalmology
  • [ISO-abbreviation] Vet Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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57. de Silva DJ, Tay E, Rose GE: Schwannomas of the lacrimal gland fossa. Orbit; 2009;28(6):433-5
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  • PURPOSE: Schwannomas are rare benign nerve sheath tumours that account for 1% of orbital tumours and, although sometimes associated with neurofibromatosis, most occur as isolated lesions and arise from branches of the ciliary or trigeminal nerves.
  • On a presumptive preoperative diagnosis of pleomorphic adenoma, the patient underwent a bone-swinging lateral orbitotomy with intact excision of a moderately-firm, lobulated lesion which proved to be a Schwannoma.
  • Although lacrimal gland remnants were present at the edge of both specimens, at surgery it was evident that the tumours completely occupied the lacrimal gland fossa and any normal orbital lobe of the lacrimal gland had undergone atrophy.
  • CONCLUSIONS: Two very rare cases of Schwannoma arising within the lacrimal gland fossa are presented, the tumours causing complete atrophy of the normal orbital lobe of the lacrimal gland.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Female. Glial Fibrillary Acidic Protein / analysis. Humans. S100 Proteins / analysis. Tomography, X-Ray Computed

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  • (PMID = 19929679.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins
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58. Arzanian MT, Khaleghnejad-Tabari A, Shamsian BS, Jadali F, Gharib A, Esfahani H: Generalized myelolipoma. Arch Iran Med; 2006 Jul;9(3):274-6
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  • Myelolipoma is a benign tumor originating from hematopoietic and adipose tissue.
  • This tumor usually develops in the adrenal gland, but rare presentations of extraadrenal myelolipoma are also reported, which usually arise from the presacral region.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Adrenal Gland Neoplasms / diagnosis. Myelolipoma / diagnosis. Orbital Neoplasms / diagnosis. Thoracic Neoplasms / diagnosis
  • [MeSH-minor] Child. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 16859067.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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59. Orawiec B, Grałek M, Stefańczyk L, Niwald A: Applicability of ultrasound in ocular tumors in children and adolescents. Klin Oczna; 2005;107(7-9):437-41
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  • [Title] Applicability of ultrasound in ocular tumors in children and adolescents.
  • PURPOSE: Evaluation of the applicability of ultrasound in children diagnosed for neoplasm of the eye.
  • Establishing the value of the obtained data concerning the image of vessels and blood flow for the diagnosis, monitoring the course of disease and results of treatment.
  • MATERIAL AND METHODS: The study comprised 80 patients diagnosed and treated for neoplasm of the eye.
  • The presence of vessels in tumor mass and blood flow in tumors were useful for differentiation between malignant and benign tumors.
  • CONCLUSIONS: Ultrasound methods used significantly improve diagnostic possibilities in orbital tumors in children.
  • The obtained pictures of vessels and flow character are typical for some tumors, which together with histopathology of tumors enables establishing of correct diagnosis.
  • CD/PD ultrasound is helpful in monitoring treatment of selected orbital tumors, enables evaluation of biological evolution of capillary hemangioma and assessment of vascularization degree of tumors treated with chemo- and radiotherapy.

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  • (PMID = 16416991.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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60. George JL, Marchal JC: [Orbital tumors in children: clinical examination, imaging, specific progression]. Neurochirurgie; 2010 Apr-Jun;56(2-3):244-8
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  • [Title] [Orbital tumors in children: clinical examination, imaging, specific progression].
  • [Transliterated title] Les tumeurs d'orbite de l'enfant : examen clinique, paraclinique, diagnostic et particularités évolutives.
  • "Orbital tumors (OT) are neoplasms of the bony orbit and contents except for the eyeball."
  • Examination must be careful: measurement, direction of proptosis, impairment of ocular motility, compressive optic neuropathy, strabismus, etc.
  • Benign tumors such as dermoid cysts or hemangiomas grow slowly, whereas rapid growth suggests a malignant tumor.
  • When a metastatic tumor is suspected, abdominal palpation and ultrasonography must be performed.
  • Ultrasonography leaves the posterior third of the orbit inaccessible to exploration.
  • The depth to which it can penetrate the orbit is limited (20mm).
  • Most of the time, standard x-rays, CT, and MR imaging allow for an adequate assessment and usually provide a diagnosis.
  • [MeSH-major] Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adult. Age Factors. Child. Disease Progression. Emotions. Exophthalmos / etiology. Humans. Leukemia / diagnosis. Leukemia / epidemiology. Leukemia / pathology. Neoplasm Metastasis / pathology. Neuroblastoma / diagnosis. Neuroblastoma / epidemiology. Neuroblastoma / pathology. Palpation. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / epidemiology. Rhabdomyosarcoma / pathology

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20303555.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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61. Fonseca Junior NL, Cha SB, Cartum J, Rehder JR: [Therapeutical effectiveness of interferon alpha in a child with craniofacial giant hemangioma: case report]. Arq Bras Oftalmol; 2008 May-Jun;71(3):423-6
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  • [Transliterated title] Eficácia terapêutica do interferon alfa em criança com hemangioma gigante craniofacial: relato de caso.
  • Hemangiomas are the most common benign tumors of infancy.
  • The diagnosis of these tumors is based on physical examination.
  • This is a case of a patient with three months of age, that presented since birth, a purplish tumor in the superior eyelid of the right eye, plain and purplish cutaneous lesions in the temporal and parietal right region.
  • On computed tomography of the skull, an orbital expansive vascularized process with intracranial extension could be observed.
  • After 9 months of treatment, a small residual orbital lesion was observed.


62. Hasegawa M, Fujisawa H, Hayashi Y, Yamashita J, Suzuki M, Matsui O: CT arteriography for orbital tumors: diagnostic and surgical value. J Clin Neurosci; 2005 Jun;12(5):548-52
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  • [Title] CT arteriography for orbital tumors: diagnostic and surgical value.
  • The aim of this study is to investigate the efficacy of dynamic computed tomography (CT) during selective angiography (CT-arteriography) of orbital tumors in the evaluation of intratumoral vascular anatomy, feeding artery territory, and histological diagnosis.
  • Among 35 consecutive cases with various orbital lesions, those cases showing tumor staining or pooling of the contrast medium on digital subtraction angiography (DSA) were evaluated by CT-arteriography (n = 14).
  • Patterns of CT-arteriography were categorized into three subgroups: homogeneous enhancement (benign lymphoid lesion), partial enhancement (schwannomas and carcinomas), and patchy multinodular enhancement (specific for cavernous angiomas).
  • CT-arteriography, with a minimal dose of contrast medium, can offer significant advantages over intravenously injected dynamic neuroimaging, and provides additional valuable preoperative information about the orbital tumor under investigation.
  • [MeSH-major] Ophthalmic Artery / pathology. Ophthalmic Artery / radiography. Orbit / pathology. Orbit / radiography. Orbital Neoplasms / blood supply. Orbital Neoplasms / radiography. Tomography, X-Ray Computed / trends
  • [MeSH-minor] Adult. Aged. Angiography / methods. Angiography / trends. Brain Neoplasms / blood supply. Brain Neoplasms / pathology. Brain Neoplasms / radiography. Carcinoma / blood supply. Carcinoma / pathology. Carcinoma / radiography. Contrast Media / standards. Diagnosis, Differential. Female. Hemangioma, Cavernous / blood supply. Hemangioma, Cavernous / pathology. Hemangioma, Cavernous / radiography. Humans. Lacrimal Apparatus / blood supply. Lacrimal Apparatus / pathology. Lacrimal Apparatus / radiography. Male. Middle Aged. Neurilemmoma / blood supply. Neurilemmoma / pathology. Neurilemmoma / radiography. Optic Nerve Neoplasms / blood supply. Optic Nerve Neoplasms / pathology. Optic Nerve Neoplasms / radiography. Predictive Value of Tests

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  • (PMID = 15982890.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Contrast Media
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63. Oukabli M, Akhaddar A, Qamouss O, Chahdi H, Rimani M, Albouzidi A: [Nasoethmoidal psammomatoid cemento-ossifiying fibroma with intraorbital extension]. Rev Stomatol Chir Maxillofac; 2010 Feb;111(1):43-5
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  • INTRODUCTION: Psammomatoid cemento-ossifying fibroma (PCOF) is a rare benign fibro-osseous lesion.
  • It is slow-growing, progressive, and benign but it can be locally extended and mimic a malignant tumor.
  • OBSERVATION: We report the unusual case of a 36-year-old woman with a nasal and ethmoid PCOF with orbital and endocranial extension.
  • The tumor was revealed by exophthalmia and nasal obstruction.
  • The diagnosis was proven histologicaly on biopsies.
  • Histologically, the differential diagnosis is difficult between fibrous dysplasia or psammomatoid meningioma.
  • [MeSH-major] Ethmoid Sinus / pathology. Fibroma, Ossifying / diagnosis. Nose Neoplasms / diagnosis. Orbital Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Exophthalmos / diagnosis. Female. Humans. Nasal Obstruction / diagnosis. Neoplasm Invasiveness. Skull Neoplasms / diagnosis

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  • (PMID = 19586648.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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64. Merani R, Khannah G, Mann S, Ghabrial R: Orbital leiomyoma: a case report with clinical, radiological and pathological correlation. Clin Exp Ophthalmol; 2005 Aug;33(4):408-11
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  • [Title] Orbital leiomyoma: a case report with clinical, radiological and pathological correlation.
  • Orbital leiomyoma is a benign tumour of smooth muscle origin that can be clinically, radiologically and histopathologically difficult to diagnose due to the rarity of leiomyomas in this location.
  • Microscopically the lesion was a well-circumscribed tumour composed of spindle cells.
  • There were no light microscopic features to suggest malignancy, and immunohistochemistry was used to confirm the diagnosis of leiomyoma.
  • Leiomyoma is a tumour that is rarely found in the orbit most likely due to the paucity of smooth muscle in this location.
  • The differential diagnosis is wide, and the role of radiology, histology and immunohistochemistry in the diagnosis of leiomyoma is discussed.
  • Surgical excision in this case excluded malignancy, provided a definitive diagnosis of a rare entity and resulted in marked clinical improvement.
  • [MeSH-major] Leiomyoma / pathology. Leiomyoma / radiography. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography
  • [MeSH-minor] Actins / analysis. Aged. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Desmin / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Ophthalmologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16033356.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Desmin
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65. Murthy R, Honavar SG: Secondary vasoproliferative retinal tumor associated with Usher syndrome type 1. J AAPOS; 2009 Feb;13(1):97-8
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  • [Title] Secondary vasoproliferative retinal tumor associated with Usher syndrome type 1.
  • Vasoproliferative retinal tumors are benign tumors of unknown origin that generally affect healthy persons between their fourth and sixth decades and may lead to severe vision loss as a result of intraretinal hemorrhages and exudates.
  • We describe a case of unilateral vasoproliferative retinal tumor associated with retinitis pigmentosa in a patient with Usher syndrome type 1.


66. Civit T, Pinelli C, Freppel S, Baylac F: [Orbital tumors arising from paranasal sinuses]. Neurochirurgie; 2010 Apr-Jun;56(2-3):174-82
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  • [Title] [Orbital tumors arising from paranasal sinuses].
  • Orbital tumors arising from paranasal sinuses comprise mucoceles and malignant ethmoidal tumors.
  • Most often, anamnestic, clinical, and radiological data as well as endoscopic biopsy performed by an ENT surgeon provide the preoperative diagnosis.
  • If the tumor is benign, surgery can cure the patient.
  • It is associated with chemotherapy and radiotherapy if the tumor is malignant.
  • [MeSH-minor] Aged. Biopsy. Combined Modality Therapy. Female. Humans. Image Processing, Computer-Assisted. Orbital Neoplasms / etiology. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography. Orbital Neoplasms / surgery. Skull / pathology. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20304444.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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67. Madge SN, Simon S, Abidin Z, Ghabrial R, Davis G, McNab A, Selva D: Primary orbital intraosseous hemangioma. Ophthal Plast Reconstr Surg; 2009 Jan-Feb;25(1):37-41
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  • [Title] Primary orbital intraosseous hemangioma.
  • PURPOSE: Primary orbital intraosseous hemangioma represents a rare, histopathologically benign, vascular tumor of the bony orbit.
  • METHODS: Retrospective, multicenter case note analysis of 4 patients with histopathologically confirmed primary orbital intraosseous hemangioma and a systematic review of the English-language literature.
  • Median duration of symptoms before presentation was 12 months (range, 1 month to 15 years) and the most frequent presentation was a painless mass, often on the orbital rim.
  • CONCLUSIONS: Primary orbital intraosseous hemangioma is a rare vascular tumor that typically presents with a mass effect in the orbits of patients in the fourth and fifth decades of life.
  • Preoperatively, it is important to be cognizant of the possible diagnosis as surgery can be complicated by life-threatening hemorrhage.
  • [MeSH-major] Hemangioma, Capillary / pathology. Hemangioma, Cavernous / pathology. Orbital Neoplasms / pathology

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  • (PMID = 19273921.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Multicenter Study
  • [Publication-country] United States
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68. Rizvi SA, Gupta Y, Gupta M: Surgical treatment and histopathological analysis of proptosis. Nepal J Ophthalmol; 2010 Jan-Jun;2(1):31-4
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  • INTRODUCTION: Inflammations and tumors of the orbit and para-orbital regions may present as proptosis.
  • MATERIALS AND METHODS: In a retrospective study, 25 cases of proptosis due to orbital and paraorbital tumours were analyzed in relation to their age, sex, and clinical and histopathological profiles.
  • According to location and type of tumour, different surgical options like anterior orbitotomy, lateral orbitotomy and medial orbitotomy were considered.
  • Primary orbital tumors were encountered in 15 cases (60%) and para-orbital in 10 (40%).
  • Of 15 primary orbital tumors, 7 (46.66%) were excised by lateral orbitotomy, another 7 (46.66%) were approached via anterior orbitotomy, whereas 1 (6.67%) was removed by medial orbitotomy.
  • Pediatric orbital tumors were quite common {7 (46.66%)}.
  • The most common benign adult tumor found in our study was pleomorphic adenoma of the lacrimal gland {3 (20%)}.
  • Proptosis due to primary orbital tumors is more common than para-orbital tumors.
  • Early diagnosis and timely surgical intervention provide good functional and cosmetic results.
  • [MeSH-major] Exophthalmos / surgery. Eye Neoplasms / pathology. Ophthalmologic Surgical Procedures / methods. Orbital Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Child. Child, Preschool. Diagnosis, Differential. Humans. Infant. Infant, Newborn. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 21141324.001).
  • [ISSN] 2072-6805
  • [Journal-full-title] Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
  • [ISO-abbreviation] Nepal J Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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69. Hirschbein MJ, Collins S, Jean WC, Chang SD, Adler JR Jr: Treatment of intraorbital lesions using the Accuray CyberKnife system. Orbit; 2008;27(2):97-105
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  • METHODS: This retrospective, non-comparative, interventional case series included 16 patients (6 women and 10 men) with lesions located wholly within the orbit.
  • Thirteen cases involved tumors (31% benign and 69% malignant), two cases presented with chronic orbital inflammation and one patient had intraorbital tissue growth secondary to Graves disease.
  • The main outcome measures analyzed were change in tumor/neoplasm size, pain, visual field preservation and visual acuity, which were followed for up to 15 months.
  • RESULTS: Twelve patients had a postoperative MRI, which revealed either a decrease or stabilization of tumor size.
  • In the five lymphoma cases there was complete disappearance of the tumor.
  • CONCLUSIONS: Staged CyberKnife radiosurgery is an effective option for the treatment of intraorbital lesions that controls tumor size, relieves pain, and preserves vision.
  • [MeSH-major] Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Radiosurgery / instrumentation. Surgery, Computer-Assisted / instrumentation

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  • (PMID = 18415869.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 4419T9MX03 / Iohexol
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70. Kloek CE, Bilyk JR, Pribitkin EA, Rubin PA: Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex. Ophthalmology; 2006 Jul;113(7):1214-9
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  • [Title] Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex.
  • PURPOSE: Tumors located in the intraconal portion of the orbital apex, especially those inferior to the optic nerve, can be difficult to access surgically, carrying a significant risk of ocular morbidity.
  • The purpose of this study was to investigate outcomes in 5 patients with benign-appearing but symptomatic tumors located in the intraconal portion of the orbital apex in which orbital decompression was performed as an alternative management strategy to resection.
  • PARTICIPANTS: Five patients were diagnosed with a compressive optic neuropathy secondary to a benign-appearing tumor at the orbital apex.
  • INTERVENTION: Each patient underwent surgical decompression of the affected orbit.
  • None of the patients had the tumor biopsied or resected.
  • MAIN OUTCOME MEASURES: Best-corrected visual acuity (VA), pupillary responses, visual fields (VFs), color vision, and orbital imaging.
  • One patient required a second orbital decompression for recurrent optic neuropathy 4 years after the initial decompression.
  • CONCLUSIONS: Orbital decompression is a therapeutic option for patients with compressive optic neuropathies from benign orbital apex tumors, offering potential improvement in optic nerve function while sparing morbidity from attempts at surgical resection.
  • [MeSH-major] Decompression, Surgical. Nerve Compression Syndromes / surgery. Optic Nerve Diseases / surgery. Orbit / surgery. Orbital Neoplasms / surgery

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  • [CommentIn] Ophthalmology. 2007 Mar;114(3):619-20; author reply 620-1 [17324707.001]
  • (PMID = 16815404.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Bernardini FP: Management of malignant and benign eyelid lesions. Curr Opin Ophthalmol; 2006 Oct;17(5):480-4
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  • [Title] Management of malignant and benign eyelid lesions.
  • PURPOSE OF REVIEW: The management of benign and malignant eyelid neoplasms has been extensively examined.
  • RECENT FINDINGS: Recent studies have focused on the results of nonsurgical approaches for benign and premalignant lesions that are routinely surgically excised.
  • In the malignant group, a consensus has been reached over the preferred method of tumor excision for basal cell carcinoma: Mohs surgery or complete surgical excision with frozen-section control of the margins offers the lowest tumor-recurrence rate.
  • Intraepithelial tumor growth is a peculiar feature of sebaceous gland carcinoma that seems to indicate an increased risk for orbital invasion.
  • Recent reports regarding the rare tumor, Merkel cell carcinoma, recommend a wide surgical excision with 5 mm margins; this may reduce the incidence of lymph-node metastasis, haematogenous spread and local recurrences.
  • SUMMARY: Although treatment of the most common benign and malignant tumours affecting the eyelids has not radically changed over the years, recent reports have significantly improved the standard of care for affected patients.

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  • (PMID = 16932064.001).
  • [ISSN] 1040-8738
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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72. Lawson SL, Medji S, Atigossou D, Bio-Tchane I, Kpemissi E, Amaglo KS: Ossifying fibroma of the maxillary sinus at the Kara (Togo) Teaching Hospital. Eur Ann Otorhinolaryngol Head Neck Dis; 2010 Dec;127(6):217-20
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  • INTRODUCTION: Ossifying fibroma of the jaw is a benign tumorous disease, somewhat rare and aggressive.
  • The CT scan of the nose and sinuses revealed a tumorous lesion of expanding bony density increasing in volume at the outer wall of the left maxillary sinus, of regular shape that contained microscopic calcifications, extending into the ipsilateral orbital floor and pushing the surrounding soft tissues forward without invading them.
  • The histopathological examination of the tumor confirmed the diagnosis of ossifying fibroma.
  • DISCUSSION: Ossifying fibroma or fibrous osteoma is a rare and benign lesion developing insidiously with a polymorphous aspect.
  • However, only examination of the gross specimen can provide the final diagnosis.

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 21051307.001).
  • [ISSN] 1879-730X
  • [Journal-full-title] European annals of otorhinolaryngology, head and neck diseases
  • [ISO-abbreviation] Eur Ann Otorhinolaryngol Head Neck Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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73. Sojka P, Pogrzebielski A, Orłowska-Heitzman J, Romanowska-Dixon B: [Mesectodermal leiomyoma of the ciliary body--case report]. Klin Oczna; 2009;111(10-12):350-3
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  • MATERIAL AND METHODS: In the left eye of the 15 years old female patient presenting 2 months history of deterioration of visual acuity a medium-pigmented, dome-shaped tumor at the inferotemporal side was detected.
  • It measured 21.6 mm in base diameter 11.2 mm in thickness and was revealed with imaging techniques such as ultrasound, MRI and orbital radiography.
  • Due to the size of the tumor and the impossibility of conducting conservative treatment the globe was eventually enucleated.
  • RESULTS: The final diagnosis was established on the basis of histopathological microscopic examination and immunohistochemical stains.
  • CONCLUSIONS: Mesectodermal leiomyoma of the ciliary body is an extremely rare benign tumor, which originates from neural crests.
  • [MeSH-major] Ciliary Body / pathology. Leiomyoma / diagnosis. Uveal Neoplasms / diagnosis

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  • (PMID = 20169895.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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74. Ramlee N, Ramli N, Tajudin LS: Pleomorphic adenoma in the palpebral lobe of the lacrimal gland misdiagnosed as chalazion. Orbit; 2007 Jun;26(2):137-9
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  • The benign tumor with its intact pseudocapsule was removed through lateral orbitotomy together with the suspicious looking orbital lobe.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eye Neoplasms / diagnosis. Lacrimal Apparatus Diseases / diagnosis
  • [MeSH-minor] Adolescent. Chalazion / diagnosis. Diagnosis, Differential. Female. Humans. Lacrimal Apparatus. Tomography, X-Ray Computed

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  • (PMID = 17613864.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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75. Kiratli H, Bulur B, Bilgiç S: Transconjunctival approach for retrobulbar intraconal orbital cavernous hemangiomas. Orbital surgeon's perspective. Surg Neurol; 2005 Jul;64(1):71-4
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  • [Title] Transconjunctival approach for retrobulbar intraconal orbital cavernous hemangiomas. Orbital surgeon's perspective.
  • BACKGROUND: Cavernous hemangioma is the most common benign intraorbital tumor found in adults.
  • We describe our experience over transconjunctival approach in 24 patients with retrobulbar intraconal orbital cavernous hemangiomas.
  • The presumptive preoperative diagnosis was based on magnetic resonance imaging findings.
  • The tumor was exposed via a transconjunctival route after temporarily disinserting an extraocular muscle depending on the location of the lesion.
  • RESULTS: In all patients, the tumor was in touch with the globe and in most cases extended to the orbital apex.
  • This method is best for tumors whose anterior borders are in contact or very close to the eye even if the posterior border abuts the orbital apex.
  • [MeSH-major] Hemangioma, Cavernous / surgery. Neurosurgical Procedures / methods. Orbital Neoplasms / surgery

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  • [CommentIn] Surg Neurol. 2006 Mar;65(3):316; author reply 316 [16488268.001]
  • (PMID = 15993191.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Rodrigues EB, Shields CL, Eagle RC Jr, Marr BP, Shields JA: Solitary intraosseous orbital myofibroma in four cases. Ophthal Plast Reconstr Surg; 2006 Jul-Aug;22(4):292-5
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  • [Title] Solitary intraosseous orbital myofibroma in four cases.
  • PURPOSE: To report four pediatric cases of a bone-destructive orbital tumor that proved to be a benign solitary intraosseous myofibroma.
  • A solitary intraosseous mass was detected in the inferior (n = 2), superotemporal (n = 1), and supranasal (n = 1) orbital walls.
  • The diagnosis was also supported by immunohistochemical studies showing positive immunoreactivity for vimentin and smooth muscle actin.
  • CONCLUSIONS: Myofibroma is a benign tumor that can occur in the orbital bony wall of children.
  • [MeSH-major] Myofibroma / pathology. Orbital Neoplasms / pathology

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  • (PMID = 16855503.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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77. Tam ES, Chen EC, Nijhawan N, Harvey JT, Howarth D, Oestreicher JH: Solitary fibrous tumor of the orbit: a case series. Orbit; 2008;27(6):426-31
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  • [Title] Solitary fibrous tumor of the orbit: a case series.
  • PURPOSE: Solitary fibrous tumor (SFT) occurs rarely in the orbit.
  • We present four such cases, representing one of the largest case series reported to date of this rare orbital tumor.
  • All four patients underwent CT scan to confirm the diagnosis of an orbital mass, which was then excised.
  • One of these cases demonstrated residual tumor on follow-up CT scan, which remained unchanged at one-year follow-up.
  • No evidence of residual tumor was found in the other three cases, despite one having malignant pathology.
  • CONCLUSION: SFT is a rare and generally benign tumor of the orbit.
  • Immunohistochemical testing with CD34 is necessary to confirm the diagnosis.
  • Although en bloc tumor resection is the definitive treatment, residual tumor may remain stable for some time.
  • [MeSH-major] Fibroma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Female. Humans. Male. Middle Aged. Neoplasm Proteins / analysis. Tomography, X-Ray Computed. Vimentin / analysis

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  • (PMID = 19085297.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Vimentin
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78. Dallaudiere B, Benayoun Y, Boncoeur-Martel M, Robert P, Adenis J, Maubon A: [Imaging features of cavernous hemangiomas of the orbit]. J Radiol; 2009 Sep;90(9 Pt 1):1039-45
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  • [Title] [Imaging features of cavernous hemangiomas of the orbit].
  • Cavernous hemangioma is the most frequent benign tumor of the orbit.
  • The clinical presentation is that of a slowly progressive intra-orbital mass with variable degree of exophthalmos.
  • CT typically demonstrates the presence of a well defined oval or rounded shaped mass but MRI provides superior evaluation of the orbit.
  • The tumor is intra-conal in 80% of cases and usually shows T1W hypo-isointensity, T2W hyperintensity and heterogeneous contrast enhancement that becomes more homogeneous on delayed imaging (5 minutes).
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 19752807.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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79. Li Y, Zhang TM, An YZ, Shi JT, Fu JD, Qiu E: [Clinical study of lacrimal gland tumor involving anterior and middle cranial fossae]. Zhonghua Yi Xue Za Zhi; 2006 Jun 20;86(23):1597-9
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  • [Title] [Clinical study of lacrimal gland tumor involving anterior and middle cranial fossae].
  • OBJECTIVE: To investigate the clinical manifestations of lacrimal gland tumor involving the anterior and middle cranial fossae and the effect of transcranial-orbital approach in treatment of such tumor.
  • METHODS: A retrospective study was conducted on the clinical data of 23 cases lacrimal gland tumor involving the anterior and middle cranial fossae confirmed by radiological examination, including 11 cases of adenoid cystic carcinoma, 6 cases of pleomorphic adenocarcinoma (malignant mixed tumor), 2 cases of adenocarcinoma, 1 case of squamous cell carcinoma, 1 case of ductal carcinoma, 1 case of mucoepidermoid carcinoma, and 1 case of benign mixed tumor, 15 males and 8 females, aged 42.5 (2 - 76), with a case history of 43 months (2 months to 27 years), with the chief complaints of progressive proptosis, disgenesia of the eye ball, and orbit pain, all undergoing transcranial-orbital operation from August 1998 to February. 2006.
  • Recurrence of tumor occurred in 4 cases, and 1 case died from distant metastasis of adenocarcinoma.
  • Adequate orbital apex decompression and exposure of the tumor can result from suitable transcranial-orbital approach.
  • However, complete surgical excision is difficult, and the tumor has a tendency to recur post-operatively.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cranial Fossa, Anterior. Cranial Fossa, Middle. Craniotomy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies

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  • (PMID = 16854296.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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80. Bikmaz K, Mrak R, Al-Mefty O: Management of bone-invasive, hyperostotic sphenoid wing meningiomas. J Neurosurg; 2007 Nov;107(5):905-12
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  • OBJECT: The hyperostosis frequently associated with sphenoid wing meningiomas is actual invasion of bone by the tumor.
  • The intracranial portion of the tumor is usually thin with en plaque spread, and the tumor tends to invade the orbit through the superior orbital fissure.
  • Seventeen of the patients had the distinguishing characteristics of hyperostotic sphenoid wing meningiomas-extensive bone invasion, en plaque dural involvement, and a minimal intracranial mass with minimal orbital involvement.
  • Revision of the orbital reconstruction was required because of postoperative enophthalmos (two cases) or restricted postoperative ocular movement (one case).
  • These lesions are generally histologically benign.
  • [MeSH-major] Hyperostosis / pathology. Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery. Meningioma / surgery. Neoplasm Invasiveness / pathology. Orbit / pathology
  • [MeSH-minor] Adult. Aged. Dura Mater / surgery. Female. Follow-Up Studies. Humans. Ki-67 Antigen / analysis. Male. Middle Aged. Neoplasm Recurrence, Local. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis. Treatment Outcome

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  • (PMID = 17977259.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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81. Kapur R, Mafee MF, Lamba R, Edward DP: Orbital schwannoma and neurofibroma: role of imaging. Neuroimaging Clin N Am; 2005 Feb;15(1):159-74
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  • [Title] Orbital schwannoma and neurofibroma: role of imaging.
  • Schwannomas are well-circumscribed ovoid masses that most commonly present in the superior orbit.
  • Although it may be difficult to differentiate these benign masses from other orbital tumors on radiologic imaging, the CT and, in particular, the MR imaging characteristics can sometimes point to the diagnosis of a nerve sheath tumor.
  • A definitive diagnosis can be made through correlation with histopathologic findings, however.
  • [MeSH-major] Magnetic Resonance Imaging. Neurilemmoma / diagnosis. Neurofibroma / diagnosis. Orbital Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 15927866.001).
  • [ISSN] 1052-5149
  • [Journal-full-title] Neuroimaging clinics of North America
  • [ISO-abbreviation] Neuroimaging Clin. N. Am.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY01792
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] United States
  • [Number-of-references] 34
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82. Al-Khiary H, Ayoubi A, Elkhamary SM: Primary orbital ganglioneuroma in a 2-year-old healthy boy. Saudi J Ophthalmol; 2010 Jul;24(3):101-4
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  • [Title] Primary orbital ganglioneuroma in a 2-year-old healthy boy.
  • He underwent orbital exploration via anterior orbitotomy incision and debulking of the tumor was done.
  • The histopathological examination confirmed the diagnosis of orbital ganglioneuroma.
  • Ganglioneuroma is an unusual benign tumor of neuroplastic origin with extremely rare orbital involvement with only one prior reported case in a youth.
  • The tumor is slow growing and non-metastasizing.

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  • (PMID = 23960884.001).
  • [ISSN] 1319-4534
  • [Journal-full-title] Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
  • [ISO-abbreviation] Saudi J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3729488
  • [Keywords] NOTNLM ; Ganglioneuroma / Neuroblastoma / Pediatric / Unilateral proptosis
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83. Kummoona R: The managements of orofacial tumors of children in Iraq. J Craniofac Surg; 2009 Jan;20(1):143-50
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  • Tumors included 20 cases of benign tumors and 35 cases malignant.
  • Treatment modalities ranged from complete surgical excision, surgical shaving operations, and deep x-ray therapy (DXT; radiotherapy) for some benign tumors.
  • Reconstruction of the mandible was carried out using a rib graft or a block of a corticocancellous bone graft from the iliac crest with reimplantation of the condyle after resection from the tumor and fixed by rigid fixation to the bone graft.
  • A temporalis muscle flap was used for the augmentation of the orbit with a frontoorbital flap after radical excision of a malignant tumor of the orbit, and a silastic implant (silicon rubber) was used for reconstruction of the orbital floor.
  • The aim of this study was to present a certain number of cases with an interesting pathologic tumor condition showing peculiar behaviors; the management of these cases was a challenge to our surgical experience.

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  • (PMID = 19165012.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Chanfi M: [Tuberous angioma in an infant: a case study]. J Fr Ophtalmol; 2005 Sep;28(7):774
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  • Tuberous angioma of the orbit is the most frequent benign tumor of the orbit in children.
  • Angiomatous tumors in general, and more particularly tuberous angioma tumors, are classed among the primary tumors of the orbit.

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  • (PMID = 16208215.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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85. Romero-Rojas AE, Díaz-Pérez JA, Lozano-Castillo A: [Malignant peripheric nerve sheath tumor of the orbit: first description of orbital location in a patient with NF1]. Neurocirugia (Astur); 2010 Feb;21(1):37-45
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  • [Title] [Malignant peripheric nerve sheath tumor of the orbit: first description of orbital location in a patient with NF1].
  • [Transliterated title] Tumor maligno de la vaina del nervio periférico (MPNST) glandular de la órbita: primera descripción de la literatura de localización orbitaria en un paciente con neurofibromatosis tipo 1.
  • INTRODUCTION: The malignant peripheric nerve sheath tumor (MPNST), is a malignant neoplastic lesion originated in Schwann cells of the lining sheath of peripheral nerves.
  • This neoplasia may appear with benign or malignant heterologous components, with divergent differentiation, as the glandular one.
  • AIM: To describe for the first time in the literature, a case of a glandular MPNST, located at the orbit and to revise the literature on this tumoral lesion.
  • CLINICAL CASE: Nine year old male, with a base diagnosis of NF1, who had exophthalmos, retro-ocular pain, headache, facial asymmetry and descent of the right eyeball, that started 1 year earlier.
  • A right Fronto-temporal craniotomy was made with fronto -orbital- zygomatic resection of the tumoral lesion.
  • The diagnosis of Glandular MPNST was made.
  • CONCLUSION: For the first time in the literature a case of Glandular MPNST located at the orbit, which occurred in child with NF1, is described.
  • This extremely uncommon neoplasia must be taken into account, in the study of biphasic malignant lesions, as its diagnosis is of great importance because of the bad prognosis of the affected patients.
  • [MeSH-major] Nerve Sheath Neoplasms / pathology. Neurofibromatosis 1 / pathology. Orbital Neoplasms / pathology

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  • (PMID = 20186373.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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86. Paiva-Neto MA, Tella Jr OI: Supra-orbital keyhole removal of anterior fossa and parasellar meningiomas. Arq Neuropsiquiatr; 2010 Jun;68(3):418-23
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  • [Title] Supra-orbital keyhole removal of anterior fossa and parasellar meningiomas.
  • We evaluated the technical aspects of the supra-orbital keyhole approach considering the indications, limitations, and complications of this approach to treat anterior cranial fossa and parasellar meningiomas.
  • Twenty-four patients (21 females; mean age, 53 + or - 8.6 years) operated on between 2002 and 2006 through a supra-orbital eyebrow approach were studied.
  • Maximal tumor diameter ranged from 1.6 to 6 cm.
  • All tumors were histologically benign.
  • The supra-orbital keyhole craniotomy is a useful minimally invasive approach to treat selected anterior fossa and parasellar meningiomas.

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  • (PMID = 20602048.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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87. Ethmoidal osteoid osteoma with orbital and intracranial extension - a case report. BMC Ear Nose Throat Disord; 2005 Mar 11;5:2
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  • [Title] Ethmoidal osteoid osteoma with orbital and intracranial extension - a case report.
  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton.
  • The ethmoid and orbital portions were approached and excised through a Weber-Ferguson incision and inferior orbitotomy.
  • Radical excision of the tumor could thus be achieved through a craniofacial approach.
  • CONCLUSION: Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures.

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  • [Cites] Br J Neurosurg. 1998 Apr;12(2):173-5 [11013675.001]
  • [Cites] Am J Clin Pathol. 1975 Mar;63(3):391-6 [1115044.001]
  • [Cites] J Laryngol Otol. 1989 Jun;103(6):634-7 [2769039.001]
  • (PMID = 15760476.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC555567
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88. Wang T, Wang X, Li M, Xu A, Chen Y: [Surgical approaches of anterior skull base tumors]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Jan;21(2):50-1
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  • Twenty-one cases were treated with anterior craniofacial approaches: Frontal subcranial combined with total maxillectomy in 8 cases or/with orbital exenteration in 5 cases, combined with lateral rhinotomy in 1 cases, combined with naso translocation with medial maxillectomy in 7 cases.
  • Frontonasal, fronto-orbital and midface degloving in one case respectively.
  • RESULT: Of the 27 malignant cases the 3 and 5-year survival rates were 81.9% (22/27) and 62.9% (17/27) respectively, and one tumor free case living well more than 9 years.
  • There were no recurrence in 10 cases with benign tumor.
  • CONCLUSIONS: Various craniofacial approaches except lateral rhinotomy provide directly satisfactory tumor exposure and facilitate enbloc resection of the naso paranasal sinus tumor with intracranial extension.
  • Partial or total maxillary swing combined with naso pyramid translocation is good for tumor involving the skull base without intracranial invasion.
  • The fronto-nasal pyramid translocation is good for removal of the upper part of nasal tumor with intracranial extension on well developed frontal sinus.
  • The fronto orbital approach is proper for removal of fronto-sphenoid tumor and midface degloving may be used in selected cases.

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  • (PMID = 17438840.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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89. Nagulić M, Nikolić I, Manojlović-Gacić E, Skender-Gazibara M: Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period. Vojnosanit Pregl; 2010 Jun;67(6):507-10
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  • [Title] Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period.
  • BACKGROUND: Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults.
  • Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare.
  • Tumor recurrence is supposed to develop from vasculature that is present already in response to a proliferate stimulus.
  • CASE REPORT: A 39-year-old female with painless proptosis of the right orbit was found to have four orbital tumors.
  • Six years later, another, the fifth one cavernous hemangioma was totally excised from the same orbit.
  • Nine years after the first operation, reorbitotomy was performed because of positive radiological and clinical signs of de novo tumor in the orbit.
  • CONCLUSION: This case show the possibility of cavernous hemangioma recurrence after a previously totally excised tumor, separated more than two decades.
  • A very long follow-up of the patients operated for these benign tumor lesions is recommended.
  • [MeSH-major] Hemangioma, Cavernous. Neoplasm Recurrence, Local. Neoplasms, Multiple Primary. Orbital Neoplasms

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  • (PMID = 20629431.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
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90. Warraich I, Dunn DM, Oliver JW: Solitary fibrous tumor of the orbit with epithelioid features. Arch Pathol Lab Med; 2006 Jul;130(7):1039-41
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  • [Title] Solitary fibrous tumor of the orbit with epithelioid features.
  • Recently, epithelioid solitary fibrous tumor has been reported in the mediastinum.
  • We report a case of solitary fibrous tumor of the orbit with biphasic architecture, including spindle cell and epithelioid components.
  • Both components demonstrated immunohistochemical features of a solitary fibrous tumor.
  • In this report, we discuss the differential diagnosis of solitary fibrous tumor with unusual epithelioid features.
  • Extrapleural solitary fibrous tumor should be included in the differential diagnosis of tumors of the orbit with a spindle cell appearance even in the presence of some epithelioid morphology.
  • [MeSH-major] Epithelioid Cells / pathology. Fibroma / pathology. Orbit / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Aged. Angiofibroma / diagnosis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Hemangiopericytoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Humans. Leiomyoma / diagnosis. Male. Meningioma / diagnosis. Neurilemmoma / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 16831031.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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91. Kashkouli MB, Khalatbari MR, Yahyavi T, Borghei Razavi H, Shayanfar N, Parvaresh MM: Primary endo-orbital osteoid osteoma. Orbit; 2008;27(3):211-3
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  • [Title] Primary endo-orbital osteoid osteoma.
  • Osteiod osteoma is a small, benign, osteoblastic tumor, which usually affects the long bone of the lower extremities and vertebrae.
  • Herein, we report the first case of endo-orbital osteoid osteoma.
  • Imaging studies showed a small (15 x 11 mm in size) lesion on the roof of the left orbit with contrast enhancement.
  • [MeSH-major] Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Osteoma, Osteoid / pathology. Osteoma, Osteoid / surgery
  • [MeSH-minor] Adult. Biopsy, Needle. Exophthalmos / diagnosis. Exophthalmos / etiology. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18569832.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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92. Krause E, Gürkov R, Klauss V: [Solitary fibrous tumor in the orbit. Case report and review of the literature]. HNO; 2009 Feb;57(2):169-72
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  • [Title] [Solitary fibrous tumor in the orbit. Case report and review of the literature].
  • [Transliterated title] Solitärer fibröser Tumor in der Orbita. Fallbericht und Literaturübersicht.
  • BACKGROUND: Solitary fibrous tumor (SFT) is a mesenchymal neoplasm with a benign growth behavior.
  • In the orbital cavity, SFT is rare.
  • Tumor growth over 7 years led to a severe exophthalmos with loss of vision.
  • CONCLUSION: SFT is a rare differential diagnosis of orbital lesions and can be appropriately treated by surgical resection.
  • [MeSH-major] Blindness / etiology. Blindness / prevention & control. Orbital Neoplasms / complications. Orbital Neoplasms / surgery. Solitary Fibrous Tumors / complications. Solitary Fibrous Tumors / surgery

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  • (PMID = 19221826.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 18
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93. Demirci H, Shields CL, Eagle RC Jr, Shields JA: Giant cell angiofibroma, a variant of solitary fibrous tumor, of the orbit in a 16-year-old girl. Ophthal Plast Reconstr Surg; 2009 Sep-Oct;25(5):402-4
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  • [Title] Giant cell angiofibroma, a variant of solitary fibrous tumor, of the orbit in a 16-year-old girl.
  • Orbital CT showed a well-circumscribed, enhancing, extraconal mass in the superior orbit, and the surgical excision was performed.
  • Repeat orbital MRI showed a well-defined, extraconal mass with loculated areas of enhancement in the left orbit superonasally.
  • Histopathologic examination showed benign, patternless spindle-cell proliferation with prominent intrinsic vascularity and multinucleated giant cells, consistent with giant cell angiofibroma, a variant of solitary fibrous tumor.
  • Giant cell angiofibroma, a variant of solitary fibrous tumor, is a rare orbital tumor that presents as a well-circumscribed, enhancing mass and can be found in children.
  • [MeSH-major] Angiofibroma / pathology. Giant Cell Tumors / pathology. Orbital Neoplasms / pathology. Solitary Fibrous Tumors / pathology
  • [MeSH-minor] Adolescent. Antigens, CD34 / metabolism. Biomarkers, Tumor / metabolism. Diplopia / diagnosis. Exophthalmos / diagnosis. Female. Humans. Magnetic Resonance Imaging. Ophthalmologic Surgical Procedures

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  • (PMID = 19966660.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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94. Subramanian N, Rambhatia S, Mahesh L, Menon SV, Krishnakumar S, Biswas J, Noronha OV: Cystic schwannoma of the orbit-a case series. Orbit; 2005 Jun;24(2):125-9
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  • [Title] Cystic schwannoma of the orbit-a case series.
  • A schwannoma is an uncommon benign orbital tumor that arises from Schwann cells in the peripheral nervous system.
  • Clinical examination alone is inadequate for the diagnosis.
  • Radiological examination, like computed tomography (CT) scans, can help in the diagnosis; however, the diagnosis can only be confirmed by histopathological examination (HPE) after excision biopsy.
  • Here, the authors report four cases of orbital schwannoma with cystic degeneration that presented with proptosis and decreased vision.
  • The histopathological examination was diagnostic for orbital schwannoma with cystic degeneration.
  • Schwannoma should be included in the differential diagnosis of cystic orbital lesions.
  • [MeSH-major] Blepharoptosis / etiology. Neurilemmoma / pathology. Orbital Neoplasms / pathology. Vision Disorders / etiology

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  • (PMID = 16191802.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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95. Dériot JB, Ledoux-Pilon A, Pilon F, Ravel A, Déchelotte P, Rigal D, Chiambaretta F: [Solitary fibrous tumor of the orbit: an unusual cause of unilateral proptosis. Case report with a review of the literature]. J Fr Ophtalmol; 2005 Nov;28(9):999-1005
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary fibrous tumor of the orbit: an unusual cause of unilateral proptosis. Case report with a review of the literature].
  • [Transliterated title] Tumeur fibreuse solitaire de l'orbite: une cause inhabituelle d'exophtalmie unilatérale. A propos d'un cas avec revue de la littérature.
  • BACKGROUND: The solitary fibrous tumor (SFT) is a spindle-cell tumor that very rarely involves the orbit.
  • Histological examination of the lesion removed by anterior orbitotomy confirmed the diagnosis of the SFT of the orbit.
  • DISCUSSION: The diagnosis of SFT is histological.
  • It is a mesenchymal tumor.
  • Immunohistochemically, the tumor cells are strongly positive for CD34 and vimentin.
  • CONCLUSION: The SFT of the orbit is a very rare and generally benign tumor.
  • It must be immunohistochemically differentiated from other spindle-cell tumors of the orbit.
  • [MeSH-major] Exophthalmos / etiology. Orbital Neoplasms / complications

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  • (PMID = 16395228.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 36
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96. Miaśkiewicz B, Lukomski M, Starska K, Józefowicz-Korczyńska M: [Ocular and orbital symptoms in benign sinonasal neopasmas]. Pol Merkur Lekarski; 2006 Feb;20(116):184-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ocular and orbital symptoms in benign sinonasal neopasmas].
  • Osteoma (0.01-0.4%) and inverted papilloma (0.5-4%) are the most common benign tumours of the nose and paranasal sinuses, whereas heamangioma occurs very rare.
  • Orbital and ocular symptoms are uncommon in these types of neoplasmas.
  • AIM OF THE STUDY: Analysis of symtoms, diagnostic procedures and treatment options in 10 patients with diagnosed orbital and ocular complications of benign tumours of the nose and paranasal sinuses.
  • Presenting orbital and ocular symptoms occured in 7 patients and in 3 left person orbital involvement was presented only radiographically and intraoperatively.
  • In 5 cases there were correlation between orbital symptoms and radiologic findings.
  • The most common presenting feature--orbital pain (6 patients) and proptosis (5 patients) were observed in papilloma and haemangioma.
  • RESULTS: Nine of the patients were operated: 4--lateral rhinotomies, 2--Denker's operations, 2--operations of sinus frontalis and/or ethmoidalis by external approach and in 1 case resection of maxilllary sinus's tumor were performed.
  • The rest of patients stay without recurrences of tumor.
  • CONCLUSION: Orbital and ocular symptoms in benign tumors of nose and paranasal sinuses do not always correlate with radiologic and intraoperative findings.
  • [MeSH-major] Headache / epidemiology. Hemangioma / epidemiology. Nose Neoplasms / epidemiology. Orbit / physiopathology. Pain / epidemiology. Pain / physiopathology. Papilloma, Inverted / epidemiology. Paranasal Sinus Neoplasms / epidemiology

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  • (PMID = 16708636.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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97. Margalit N, Ezer H, Fliss DM, Naftaliev E, Nossek E, Kesler A: Orbital tumors treated using transcranial approaches: surgical technique and neuroophthalmogical results in 41 patients. Neurosurg Focus; 2007;23(5):E11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital tumors treated using transcranial approaches: surgical technique and neuroophthalmogical results in 41 patients.
  • OBJECT: Orbital tumors can be divided schematically into primary lesions, originating from the orbit itself, and secondary lesions, extending to the orbit from neighboring structures.
  • The authors evaluate 41 cases of benign and malignant tumors involving the orbit and discuss the surgical challenge, which involves tumor removal, preserving visual function and cosmetic reconstruction.
  • METHODS: The authors performed a retrospective analysis of a series of all cases involving patients who underwent surgery for treatment of orbital tumors in their hospital between December 2003 and December 2006.
  • Two patients had metastases to the orbit.
  • Maxillectomy through a Weber-Ferguson approach or a facial degloving approach was added in 5 cases to complete tumor removal.
  • Excluding the patients who underwent orbital exenteration, none of the patients had visual deterioration following surgery, and most had no change in their visual condition.
  • Two patients had temporary diplopia, 1 had a cerebrospinal fluid leak, and 1 had enophthalmos following removal of an orbital osteosarcoma.
  • CONCLUSIONS: Orbital tumors can be treated safely using transcranial approaches in many cases.
  • Preoperative imaging can accurately define the compartments involved and the surgical approach needed for tumor removal.
  • A multidisciplinary team of surgeons facilitates optimal tumor removal and skull base sealing as well as good cosmetic results.
  • [MeSH-major] Ophthalmologic Surgical Procedures / methods. Orbital Neoplasms / surgery. Reconstructive Surgical Procedures / methods


98. Durden FL Jr, Moore CE, Muller S: Verrucous carcinoma of the paranasal sinuses: a case report. Ear Nose Throat J; 2010 Jul;89(7):E21-3
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  • The tumor grows locally invasive but is histologically benign and metastasizes rarely.
  • We present a case of verrucous carcinoma involving the paranasal sinuses, nasal cavity, cranium, and orbit.
  • This case highlights the difficulty of pathologic diagnosis and management options for a rare neoplastic lesion.
  • [MeSH-minor] Biopsy. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiation effects. Nasal Cavity / surgery. Neoplasm Invasiveness. Neoplasm Staging. Orbital Neoplasms / pathology. Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Skull / pathology. Skull / radiation effects. Skull / surgery. Skull Neoplasms / pathology. Skull Neoplasms / radiotherapy. Skull Neoplasms / surgery

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  • (PMID = 20628974.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Ganly I, Gross ND, Patel SG, Bilsky MH, Shah JP, Kraus DH: Outcome of craniofacial resection in patients 70 years of age and older. Head Neck; 2007 Feb;29(2):89-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thirty-five patients had a malignant tumor and 1 patient a benign tumor; 15 (42%) had high-grade, 17 (47%) intermediate-grade, and 4 (11%) low-grade pathology.
  • Complications were classified into overall, local, central nervous system (CNS), systemic, and orbital.
  • Local wound complications occurred in 11 (30%), CNS in 12 (33%), systemic in 6 (17%), and orbital in 1 (3%).
  • [MeSH-minor] Age Factors. Aged. Aged, 80 and over. Carcinoma / mortality. Carcinoma / pathology. Carcinoma / surgery. Cranial Fossa, Anterior / surgery. Cranial Fossa, Middle / surgery. Databases as Topic. Esthesioneuroblastoma, Olfactory / mortality. Esthesioneuroblastoma, Olfactory / pathology. Esthesioneuroblastoma, Olfactory / surgery. Female. Follow-Up Studies. Humans. Male. Melanoma / mortality. Melanoma / pathology. Melanoma / surgery. Neoplasm Recurrence, Local. Prospective Studies. Surgical Flaps. Survival Analysis


100. Banhiran W, Casiano RR: Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm. Curr Opin Otolaryngol Head Neck Surg; 2005 Feb;13(1):50-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm.
  • In the recent literature, emphasis has been on the endoscopic surgery of benign tumors, especially inverted papilloma and nasopharyngeal angiofibroma.
  • Other benign neoplasms have also been reported, but only in small case reports.
  • Especially for the more common benign neoplasms, such as inverted papilloma and early stage angiofibroma.
  • Large tumor size, intracranial or orbital extension, and extensive frontal or infratemporal fossa involvement are relative, but not absolute limitations.

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  • (PMID = 15654216.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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