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Items 1 to 100 of about 1481
1. Ben Hamouda H, Ayat A, Elloumi I, Belaid L, Bouzaiène M, Korbi S, Soua H, Sfar MT: Obstructive congenital epulis. Eur Ann Otorhinolaryngol Head Neck Dis; 2010 May;127(2):86-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Congenital epulis, known as a congenital gingival granular cell tumor, is a benign tumor and very rare in newborns.
  • DISCUSSION: We report the clinical case of a female full-term newborn who presented a tumor on the upper gum obtruding into the oral cavity discovered at birth.
  • The pregnancy was followed normally with three prenatal ultrasounds, which did not show abnormalities.
  • Histological examination confirmed the diagnosis of gingival tumor with granular cells and absence of signs of malignancy.
  • CONCLUSION: Prenatal diagnosis is fundamental in the therapeutic approach to this rare lesion but remains difficult because the findings are non specific and the generally late development of the tumor.
  • [MeSH-major] Gingival Neoplasms / congenital. Granular Cell Tumor / congenital

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20822763.001).
  • [ISSN] 1879-730X
  • [Journal-full-title] European annals of otorhinolaryngology, head and neck diseases
  • [ISO-abbreviation] Eur Ann Otorhinolaryngol Head Neck Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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2. Chen X, Zhang X, Zhang S, Lü B: Angioleiomyomas in the bilateral broad ligaments. Int J Gynecol Pathol; 2010 Jan;29(1):39-43
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  • Immunostaining demonstrated that the tumor cells were positive for alpha-smooth muscle actin, desmin, estrogen receptor, and progesterone receptor.
  • This rare benign tumor should be differentiated from other mesenchymal neoplasms with prominent blood vessels.

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  • (PMID = 19952939.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Fukuma E: [Endoscopic breast surgery for breast cancer]. Nihon Geka Gakkai Zasshi; 2006 Mar;107(2):64-8
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  • With EBS technique, any kind breast surgery, sentinel node biopsy, reconstruction, augmentation, and benign tumor excision, could be performed through same skin incisions.

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  • (PMID = 16613205.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 17
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4. Pareja MJ, Vargas MT, Sánchez A, Ibáñez J, González-Cámpora R: Cytogenetic study of a pulmonary sclerosing hemangioma. Cancer Genet Cytogenet; 2009 Nov;195(1):80-4
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  • Pulmonary sclerosing hemangioma (PSH) is an uncommon benign tumor that presents as a solitary asymptomatic and slow-growing nodule.
  • Both sexes are affected by this tumor, but women more frequently than men.
  • PTEN (10q23) and IgH (14q32) probes were analyzed in interphase nuclei and paraffin-embedded tissues of tumor cells.

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  • (PMID = 19837274.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Lin TM, Chang HW, Wang KH, Kao AP, Chang CC, Wen CH, Lai CS, Lin SD: Isolation and identification of mesenchymal stem cells from human lipoma tissue. Biochem Biophys Res Commun; 2007 Oct 5;361(4):883-9
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  • Lipoma is a benign neoplasm of normal fat cells that appears as a soft, movable swelling, often with a slight yellowish coloration.

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  • (PMID = 17679141.001).
  • [ISSN] 0006-291X
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Chen YR, Chang CN, Tan YC: Craniofacial fibrous dysplasia: an update. Chang Gung Med J; 2006 Nov-Dec;29(6):543-9
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  • It is a bone tumor that, although benign, has the potential to cause significant cosmetic and functional disturbance, particularly in the craniofacial skeleton.

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  • (PMID = 17302216.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China (Republic : 1949- )
  • [Number-of-references] 50
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7. Chang KT, Chadha NK, Leung R, Shago M, Phillips MJ, Thorner PS: Lymphadenoma: case report of a rare salivary gland tumor in childhood. Pediatr Dev Pathol; 2010 Jul-Aug;13(4):331-7
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  • [Title] Lymphadenoma: case report of a rare salivary gland tumor in childhood.
  • Lymphadenoma of the salivary gland is a rare benign tumor with only 11 reported cases in the English language literature, most of which have occurred in adults.
  • The tumor was composed of variably sized cystic cavities within abundant reactive lymphoid tissue.
  • Tumor cells were not cycling as determined by MIB1 immunostaining, and the tumor karyotype was normal.
  • Although this tumor is rarely encountered by pediatric pathologists, awareness of its existence is important to distinguish it from possible malignant mimics, such as lymphoepithelial carcinoma and metastatic mucoepidermoid carcinoma in a lymph node.
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / secondary. Cytoplasmic Structures / ultrastructure. Diagnosis, Differential. Female. Humans. Keratins / metabolism. Lymphocytes / ultrastructure. Plasma Cells / ultrastructure. Proto-Oncogene Proteins c-kit / metabolism. Trans-Activators / metabolism. Transcription Factors. Treatment Outcome. Tumor Suppressor Proteins / metabolism

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  • (PMID = 20021220.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 68238-35-7 / Keratins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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8. Luo HY, Li TJ: Odontogenic tumors: a study of 1309 cases in a Chinese population. Oral Oncol; 2009 Aug;45(8):706-11
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  • Of the 1309 OTs, 94.04% were benign and 5.06% were malignant.
  • The most frequent benign tumor was keratocystic odontogenic tumor (38.73%), followed by ameloblastoma (36.52%) and odontomas (6.11%).

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  • (PMID = 19147397.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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9. Zheng LW, Li FB, Liu RZ, Ji RG, Zhao ZW: [Clinical analysis of 87 cases of testicular tumor]. Zhonghua Nan Ke Xue; 2005 Jun;11(6):445-7
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  • [Title] [Clinical analysis of 87 cases of testicular tumor].
  • OBJECTIVE: To improve the diagnosis and treatment of testicular tumor.
  • METHODS: Eighty-seven cases of testicular tumor were retrospectively studied.
  • RESULTS: Of the total number, 79 cases were pathologically diagnosed as germ cell tumor (90.1%), among which there were 44 cases of seminoma (55.7%) and 7 cases of benign tumor (8.1%).
  • Nonseminoma germ cell tumor (NSGCT) was found mainly among those under 5 and from 18 to 40 years of age, while seminoma chiefly among those beyond 17, and testis tumor was rare among those between 5 and 17 years old (1 case only).
  • (1) Testicular tumors are mostly germ cell tumors. (2) NSGCT develops mainly among those under the age of 5 and from 18 to 40. (3) Seminoma is rare in those under 18. (4) Testicular tumor rarely develops among those between 5 and 17 years old. (5)Three-year and 5-year survival rates for seminoma are higher than those for NSGCT.

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  • (PMID = 15999491.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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10. Notarnicola A, Moretti L, Cocca MP, Martucci A, Orsini U, Moretti B: Low-grade fibromyxoid sarcoma of the medial vastus: a case report. Musculoskelet Surg; 2010 Nov;94(2):109-12
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  • Low-grade fibromyxoid sarcoma (LGFMS) was first described by Evans in 1987, and since then, just over 150 cases have been reported, showing the rarity of this tumor.
  • Immuno-histological examination demonstrated the lesion to be a LGFMS, defined as a benign tumor but with a high incidence of local and distant recurrence (5-10%).
  • We recommend that the eventuality of observing this rare tumor be borne in mind, and that care be taken to perform a complete, ample excision.
  • [MeSH-minor] Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control

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  • (PMID = 20376587.001).
  • [ISSN] 2035-5114
  • [Journal-full-title] Musculoskeletal surgery
  • [ISO-abbreviation] Musculoskelet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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11. Ilie M, Hofman V, Pedeutour F, Attias R, Santini J, Hofman P: Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis. Pathol Res Pract; 2010 Jan 15;206(1):66-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Salivary gland oncocytic lipoadenoma is an exceptional benign tumor composed of mature adipose tissue associated with a mixture of oncocytes.
  • A 64-year-old male developed a left parotid gland, well-encapsulated tumor measuring 3.5 x 3 cm(2), showing mature fat cells associated with oncocytic changes of epithelial components.
  • [MeSH-minor] Disease-Free Survival. Humans. Immunohistochemistry. Lipoma / metabolism. Lipoma / pathology. Lipoma / surgery. Male. Middle Aged. Neoplasm Proteins / metabolism

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  • [Copyright] Copyright 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 19346081.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Neoplasm Proteins
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12. Fujiwaki R, Ohnuma H, Miura H, Sawada K: Uterine lipoleiomyoma in an elderly patient: a case report. Arch Gynecol Obstet; 2008 May;277(5):471-4
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  • BACKGROUND: Uterine lipoleiomyoma is a rare, fat-containing, benign tumor.
  • The clinical features and optimal treatment of this tumor remain unclear.
  • Magnetic resonance imaging demonstrated a uterine tumor with inhomogeneously high signal intensity.
  • CONCLUSION: In cases where the radiological appearance of a uterine tumor in an elderly patient is suspicious for liposarcoma, the possibility of a benign lipoleiomyoma should be considered.

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  • (PMID = 17987306.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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13. Lu R, Liang WW, Yang Z, Liu CH, Zhao YT: [A case report of giant cemento-ossifying fibroma]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2010 Dec;28(6):682-3
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  • Cemento-ossifying fibroma is a rare benign tumor from periodontium, which usually occurs in mandible body and mandible ramus.

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  • (PMID = 21365855.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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14. Hollowell ML, Goulart RA, Gang DL, Otis CN, Prior J, Sachs BF, Pantanowitz L: Cytologic features of müllerian papilloma of the cervix: mimic of malignancy. Diagn Cytopathol; 2007 Sep;35(9):607-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Müllerian papilloma is a rare benign tumor of the cervix and/or vagina that occurs predominantly in young children.
  • The cytologic features of benign müllerian papilloma have never been described.
  • We report for the first time, to our knowledge, the cytologic findings of a benign müllerian papilloma from the vaginal fluid specimen of a 15-mo-old girl using touch prep, ThinPrep, and cell block preparations.
  • The deceptive cytologic features of a cellular specimen with complex papillary fronds composed of overlapping and crowded small hyperchromatic cells, with a high nuclear:cytoplasmic ratio, and feathering in this case resembled a malignant neoplasm.
  • The clinical findings and cytomorphology of a benign müllerian papilloma can mimic those of malignant lesions of the female lower genital tract such as sarcoma botryoides and adenocarcinoma.


15. Wu JK, Adepoju O, De Silva D, Baribault K, Boscolo E, Bischoff J, Kitajewski J: A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma. Angiogenesis; 2010 Mar;13(1):15-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Infantile hemangioma (IH) is the most common benign tumor of infancy, yet its pathogenesis is poorly understood.
  • Notch family members are known to play a role in vascular development during embryogenesis and postnatal tumor angiogenesis, yet the role of Notch signaling in the pathogenesis of IH has not been investigated.

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  • (PMID = 20069356.001).
  • [ISSN] 1573-7209
  • [Journal-full-title] Angiogenesis
  • [ISO-abbreviation] Angiogenesis
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL096384-01; United States / NCI NIH HHS / CA / R01 CA136673; United States / NHLBI NIH HHS / HL / R01 HL096384; United States / NHLBI NIH HHS / HL / R01 HL096384-01
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / RNA, Messenger; 0 / Receptors, Notch; 134324-36-0 / Serrate proteins
  • [Other-IDs] NLM/ NIHMS176679; NLM/ PMC2846229
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16. Hong KH, Yang YS: Intraoral approach for the treatment of submandibular salivary gland mixed tumors. Oral Oncol; 2008 May;44(5):491-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pleomorphic adenoma represents a most common benign neoplasm of major salivary glands.
  • Most occurrences of this benign tumor in the submandibular gland have been treated surgically without difficulty via transcervical approach.
  • In this study, we introduced the intraoral approach for the removal of the submandibular mixed tumor.
  • During surgery the tumor and submandibular gland are easily dissected from surrounding tissue and removed through intraoral incision.
  • All patients were followed up for the recurrence of the tumor from 20 months to 10 years.
  • One patient showed a tumor recurrence at the early stage of this approach.
  • We propose that the benign mixed tumor of the submandibular gland could be removed easily via intraoral route without an external scar or nerve injury.

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  • (PMID = 17827052.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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17. Biswas PK, Niu J, Frederico T, Gogonea V: Numerical simulation and graphical analysis of in vitro benign tumor growth: application of single-particle state bosonic matter equation with length scaling. J Mol Model; 2006 Jul;12(5):641-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Numerical simulation and graphical analysis of in vitro benign tumor growth: application of single-particle state bosonic matter equation with length scaling.
  • We describe the application of a non-linear single-particle state bosonic condensate equation to simulate multicellular tumor growth by treating it as a coupling of two classical wave equations with real components.
  • The features of quiescent and necrotic cells, which result from poor nutrient diffusion into a tumor, have been found to correspond quite well to experimental data when they are modeled as depending on higher cell density.
  • Classical hallmarks of benign tumor growth, such as the initial rapid growth, followed by a dramatic collapse in the proliferating cell count and a strong re-growth thereafter appear quite encouragingly in the theoretical results.
  • A tool for graphical analysis of the tumor simulation results has been developed to provide morphological information about tumors at various growth stages.
  • The model and the graphical analysis can be extended further to create an effective tool to predict/monitor tumor growth.

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  • [Cites] In Silico Biol. 2002;2(3):393-406 [12542422.001]
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  • (PMID = 16555065.001).
  • [ISSN] 0948-5023
  • [Journal-full-title] Journal of molecular modeling
  • [ISO-abbreviation] J Mol Model
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Germany
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18. Yu YH, Son BK, Jun DW, Kim SH, Jo YJ, Park YS, Hong BW, Joo JE: [A case of desmoid tumor presenting as intra-abdominal abscess]. Korean J Gastroenterol; 2009 May;53(5):315-9
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  • [Title] [A case of desmoid tumor presenting as intra-abdominal abscess].
  • Desmoid tumor is a rare benign tumor derived from fibrous sheath or musculoaponeurotic structure.
  • The tumor is benign histologically but considered as malignant clinically because it has high propensity on infiltrative growth with local invasion and tendency to recurrence after local excision.
  • Especially, when this tumor happens to be in the intra-abdomen, the prognosis is worse because it can cause intestinal obstruction, ureter obstruction and, fistula formation.
  • This tumor occurs more frequently in patients with familial adenomatous polyposis (FAP), in post-partume women, and at old surgical incision site.
  • We report a rare case of the young male patient who presented with an acute abdomen and underwent laparotomy and was found to have an intra-abdominal desmoid tumor with abscess formation.

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  • (PMID = 19458469.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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19. Liess BD, Horst JA, Zitsch RP 3rd: Sphenoid sinus paraganglioma: first reported case. Am J Otolaryngol; 2007 Sep-Oct;28(5):347-9
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  • Rarely, this benign tumor may occur in the nose and paranasal sinus.
  • We report a case of paraganglioma involving the sphenoid sinus, discuss histologic characteristics, and review this tumor.

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  • [CommentIn] Am J Otolaryngol. 2009 Jan-Feb;30(1):70; author reply 71 [19027520.001]
  • (PMID = 17826539.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Onuki T, Iguchi K, Inagaki M, Suzuki K: [Lipofibroadenoma of the thymus]. Kyobu Geka; 2009 May;62(5):395-8
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  • The patient was a 32-year-old male who displayed an anterior mediastinal tumor on a chest computed tomography (CT) scan while being treated for pneumonia.
  • The tumor was localized within the thymus, and the diameter was 3 cm.
  • No significant change was observed in the tumor on a CT scan taken 6 months after the 1st scan.
  • Lymphocytes were scarce within the tumor with abundant interstitial stroma, and the tumor epithelial cells displayed restiform and dendritic structures.
  • A very small amount of calcification was detected within the tumor using alizarin red staining.
  • Based on the histopathological findings, it was considered to be a benign tumor with little growth potential, and which had been present for a long period of time.

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  • (PMID = 19425382.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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21. Romano A, Chibbaro S, Makiese O, Marsella M, Mainini P, Benericetti E: Endoscopic removal of a central neurocytoma from the posterior third ventricle. J Clin Neurosci; 2009 Feb;16(2):312-6
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  • Central neurocytoma is a rare benign tumor that most commonly arises within the ventricular system of young adults.
  • The patient underwent endoscopic assisted gross total resection of the tumor with the aid of intraoperative laser followed by standard third ventriculostomy; no further treatment was required.
  • Serial post-operative MRIs show neither residual nor recurrent tumor.
  • Thus, posterior third ventricle central neurocytomas are relatively benign tumors that can be successfully removed using a minimally invasive approach, thereby avoiding both the morbidity related to conventional open craniotomy and the potential toxicity of any adjuvant treatment.

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  • (PMID = 19084413.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Technical Report
  • [Publication-country] Scotland
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22. Del Gobbo A, Bimbatti M, Ferrero S: A case report of mesenteric mucinous cystoadenoma with review of the literature. BMC Gastroenterol; 2010;10:105
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  • BACKGROUND: Few cases of primary retroperitoneal mucinous cystoadenoma, a rare benign tumor, have been reported in the literature so far.
  • Unless biologically benign, this tumour can cause relevant clinical symptoms related to the size and site (compression or obstruction of organs).
  • Surgical resection is the only way to treat mucinous cystoadenomas, and to have the histological confirmation that the removed mass is a benign tumor.

  • Archivio Istituzionale della Ricerca Unimi. Full text from AIR - Univ. Milan .
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  • [Cites] Pathol Int. 2004 Feb;54(2):132-8 [14720145.001]
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  • (PMID = 20840746.001).
  • [ISSN] 1471-230X
  • [Journal-full-title] BMC gastroenterology
  • [ISO-abbreviation] BMC Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2944338
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23. Abdollahi A, Folkman J: Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy. Drug Resist Updat; 2010 Feb-Apr;13(1-2):16-28
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  • [Title] Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy.
  • The universality of this approach is demonstrated by the broad spectrum of malignant and benign tumor entities, as well as non-neoplastic diseases, that are currently treated with anti-angiogenic agents.
  • In contrast to tumor cell targeting therapies, the development of acquired drug resistance (e.g., via mutations in growth factor receptor signaling genes) has not been described yet for the principal target of anti-angiogenic therapy--the tumor endothelium.
  • Moreover, the tumor endothelium has emerged as a critical target of conventional cancer therapies, such as chemotherapy and radiotherapy.
  • The presumption that tumor growth and metastasis are angiogenesis-dependent implies that the number of potential targets of an anti-cancer therapy could be reduced to those that stimulate the angiogenesis process.
  • Direct targeting of tumor endothelium via, e.g., endogenous angiogenesis inhibitors poses another promising but clinically less explored therapeutic strategy.
  • Indeed, the majority of current anti-angiogenic approaches block the activity of a single or at most a few pro-angiogenic proteins secreted by tumor cells or the tumor stroma.
  • Here, we discuss current concepts and propose novel strategies to overcome tumor evasion of anti-angiogenic therapy.
  • We believe that early detection of tumors, prediction of tumor evasive mechanisms and rational design of anti-angiogenic combinations will direct anti-angiogenic therapy towards its ultimate goal--the conversion of cancer to a dormant, chronic, manageable disease.
  • [MeSH-major] Angiogenesis Inhibitors / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Drug Delivery Systems / methods. Drug Resistance, Neoplasm. Neoplasm Invasiveness / prevention & control. Neoplasm Metastasis / prevention & control. Neoplasms / drug therapy

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  • [Copyright] 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20061178.001).
  • [ISSN] 1532-2084
  • [Journal-full-title] Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
  • [ISO-abbreviation] Drug Resist. Updat.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors
  • [Number-of-references] 152
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24. Robles R, Abellán B, Marín C, Fernández JA, Ramírez P, Morales D, Ramírez M, Sánchez F, Parrilla P: [Laparoscopic resection of solid liver tumors. Presentation of our experience]. Cir Esp; 2005 Oct;78(4):238-45
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  • Preoperative diagnosis was liver metastases from colorectal carcinoma in 11 patients and benign tumor in the remaining five patients.
  • VII) and two local resections of benign tumors.
  • CONCLUSION: LLR of benign SLTs shows all the advantages of laparoscopy.

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  • (PMID = 16420832.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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25. Gupta R, Khurana N, Singh DK, Singh S: Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):447-8
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  • [Title] Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm.

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  • (PMID = 18723990.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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26. Ravindra S, Suguna BV: Cytomorphology of tubular adenoma breast--a case report. Indian J Pathol Microbiol; 2006 Apr;49(2):267-8
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  • Tubular adenoma a 'pure adenoma' is a benign neoplasm of breast presenting clinically like fibroadenoma.

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  • (PMID = 16933735.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 7
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27. Sivakumar S: Pilomatrixoma as a diagnostic pitfall in fine needle aspiration cytology: a case report. Acta Cytol; 2007 Jul-Aug;51(4):583-5
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  • BACKGROUND: Pilomatrixoma (pilomatrixoma, calcifying epithelioma of Malherbe) is a relatively uncommon, benign neoplasm arising from the skin adnexa.
  • The tumor can cause diagnostic difficulty not only for the clinician but also for the cytologist.
  • Three preliminary differential diagnoses were offered: mucoepidermoid carcinoma of the submandibular salivary gland, squamous cell carcinomatous deposit in a submandibular lymph node and calcifying odontogenic tumor.
  • CONCLUSION: The cytologic presentation of pilomatrixoma of the right submandibular region can masquerade as that of a malignant tumor, in this case mucoepidermoid carcinoma, squamous cell carcinoma or odontogenic tumor.

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  • (PMID = 17718128.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Algin C, Hacioğlu A, Aydin T, Ihtiyar E: Esophagectomy in esophageal lipoma: report of a case. Turk J Gastroenterol; 2006 Jun;17(2):110-2
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  • Lipoma is an uncommon benign tumor of the alimentary tract and its overall incidence is 4.1%, but that of the esophagus is extremely rare, with an incidence of only 0.4%.
  • Computed tomography and abdominal ultrasonography were performed because of endoscopic suspicion of submucosal tumor, and the mass was confirmed to be a lipoma in the wall of the esophagus.
  • Surgical excision by enucleation of the tumor is the preferred treatment of esophageal lipoma, but opening of the esophageal mucosa during this procedure is a rare cause for esophageal resection.

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  • (PMID = 16830292.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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29. Schulz R, Horstmann S, Jokeit H, Woermann FG, Ebner A: Epilepsy surgery in professional musicians: subjective and objective reports of three cases. Epilepsy Behav; 2005 Nov;7(3):552-8
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  • We describe a small series of three professional musicians who had right (two patients) and left (one patient) temporal lobe epilepsy surgery with the histological diagnoses of hippocampal sclerosis (two patients) and benign tumor (one patient, xanthoastrocytoma).

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  • (PMID = 16143569.001).
  • [ISSN] 1525-5050
  • [Journal-full-title] Epilepsy & behavior : E&B
  • [ISO-abbreviation] Epilepsy Behav
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hypnotics and Sedatives; GWH6IJ239E / Amobarbital
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30. Wang SM, Huang DM, Li B, Ruan JD: [Association of CK20 expression with the progression, metastasis and prognosis of breast cancer]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2009 Aug;25(8):706-7
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  • AIM: To analyze the expression of CK20 in human breast cancer, and to evaluate the association between its expression and tumor's progression and prognosis.
  • METHODS: 86 cases with breast cancer, 20 cases of benign tumor tissues were examined for the expression of CK20 by immunohistochemical staining.
  • RESULTS: The positive rate of CK20 expression in breast cancer was 80.23% (69/86), which was significantly higher than that in benign tumor tissues of breast [20.00% (4/20), P<0.01].
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Neoplasm Staging. Prognosis

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  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 19664394.001).
  • [ISSN] 1007-8738
  • [Journal-full-title] Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
  • [ISO-abbreviation] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Keratin-20
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31. Sojka P, Pogrzebielski A, Orłowska-Heitzman J, Romanowska-Dixon B: [Mesectodermal leiomyoma of the ciliary body--case report]. Klin Oczna; 2009;111(10-12):350-3
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  • MATERIAL AND METHODS: In the left eye of the 15 years old female patient presenting 2 months history of deterioration of visual acuity a medium-pigmented, dome-shaped tumor at the inferotemporal side was detected.
  • Due to the size of the tumor and the impossibility of conducting conservative treatment the globe was eventually enucleated.
  • CONCLUSIONS: Mesectodermal leiomyoma of the ciliary body is an extremely rare benign tumor, which originates from neural crests.

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  • (PMID = 20169895.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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32. Ozcan C, Apa DD, Aslan G, Gülhan S, Görür K: Mycobacterium tuberculosis infection within parotid gland Warthin tumor. J Craniofac Surg; 2008 Nov;19(6):1561-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mycobacterium tuberculosis infection within parotid gland Warthin tumor.
  • The second is a chronic, slow-growing, painless, and firm parotid mass mimicking a neoplasm.
  • Warthin tumor is a well-known benign neoplasm of the salivary glands.
  • It is the second most common tumor of the parotid gland.
  • Mycobacterium tuberculosis within Warthin tumor is also unusual.
  • Five cases with parotid gland tuberculosis within Warthin tumor were reported in the literature.
  • In this report, we present a new patient with parotid gland tuberculosis within the Warthin tumor.
  • We also discussed the possible mechanisms of development of infection within Warthin tumor.

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  • (PMID = 19098552.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents; 0 / Contrast Media; 0 / DNA, Bacterial
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33. Pancholi V, Munjal K, Jain M, Munjal S, Agrawal R, Nandedkar S: Preoperative diagnosis of renal angiomyolipoma with fine needle aspiration cytology: a report of 3 cases. Acta Cytol; 2006 Jul-Aug;50(4):466-8
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  • BACKGROUND: Angiomyolipoma is a rare benign neoplasm, commonly involving the kidney.

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  • (PMID = 16901016.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Liao Y, Zeng H, Wang X, Huang Y, Chen N, Ge B, Tang L, Luo Q: Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland. Exp Eye Res; 2009 Jan;88(1):4-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenoid cystic carcinoma (ACC) of lachrymal gland is a malignant tumor with a poor prognosis, while, pleomorphic adenoma (PA) is the benign tumor of lachrymal gland epithelia.
  • Livin expression was almost undetectable in both malignancy and benign lesion of lachrymal gland.
  • Survivin expression in lachrymal tumors was localized in cytoplasm exclusively, and its expression was related to T staging and proliferative index in ACC, multivariate analysis demonstrated that Survivin was the only factor that could independently predict poor prognosis of ACC (RR = 3.681, 95%CI: 1.068-12.688, p = 0.039).
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Inhibitor of Apoptosis Proteins / metabolism. Lacrimal Apparatus Diseases / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Gene Expression. Humans. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Staging. Paraffin Embedding. Prognosis. RNA, Messenger / genetics. Reverse Transcriptase Polymerase Chain Reaction / methods. Survival Analysis. Young Adult

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  • (PMID = 18955046.001).
  • [ISSN] 1096-0007
  • [Journal-full-title] Experimental eye research
  • [ISO-abbreviation] Exp. Eye Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Inhibitor of Apoptosis Proteins; 0 / Neoplasm Proteins; 0 / RNA, Messenger
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35. Sirohi D, Sharma R, Sinha R, Suresh Menon P: Salivary gland neoplasms: an analysis of 74 cases. J Maxillofac Oral Surg; 2009 Jun;8(2):164-6
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  • Between 2006 and 2009, 74 cases of salivary gland neoplasms were analyzed retrospectively, of which 44 (60%) were benign and 30 (40%) malignant.
  • The most common benign neoplasm was pleomorphic adenoma (64%), and the most common malignant neoplasm were adenoid cystic carcinoma (17%) and mucoepidermoid carcinoma (23%).

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  • [Cites] J Craniomaxillofac Surg. 2000 Feb;28(1):56-61 [10851675.001]
  • [Cites] Int J Oral Maxillofac Surg. 2002 Jun;31(3):257-61 [12190130.001]
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  • (PMID = 23139498.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453927
  • [Keywords] NOTNLM ; Parotid / Pleomorphic adenoma / Sublingual / Submandibular / mucoepidermoid carcinoma
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36. Venkatesh K, Saini ML, Rangaswamy R, Murthy S: Neural fibrolipoma without macrodactyly: a subcutaneous rare benign tumor. J Cutan Pathol; 2009 May;36(5):594-6
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  • [Title] Neural fibrolipoma without macrodactyly: a subcutaneous rare benign tumor.
  • Neural fibrolipoma, also known as lipofibromatous hamartoma of nerves and neurolipomatosis, is a rare subcutaneous benign lesion involving the upper extremity with a marked predilection for median nerve.

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  • (PMID = 19476532.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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37. Vasconcelos BC, Andrade ES, Rocha NS, Morais HH, Carvalho RW: Treatment of large ameloblastic fibroma: a case report. J Oral Sci; 2009 Jun;51(2):293-6
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  • Ameloblastic fibroma (AF) is an extremely rare true mixed benign tumor that can occur in either the mandible or the maxilla, but is most frequently found in the posterior region of the mandible.

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  • (PMID = 19550100.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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38. Wang WH, Lee SS, Wang LF, Lai CS: Repair oronasal fistula in a treated juvenile nasopharyngeal angiofibroma patient. J Plast Reconstr Aesthet Surg; 2007;60(10):1148-51
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  • OBJECTIVE: The juvenile nasopharyngeal angiofibroma (JNA) is a benign neoplasm that affects mostly young males.

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  • (PMID = 17825778.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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39. Venturi A, Piscaglia F, Vidili G, Flori S, Righini R, Golfieri R, Bolondi L: Diagnosis and management of hepatic focal nodular hyperplasia. J Ultrasound; 2007 Sep;10(3):116-27
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  • Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver, after hemangioma.

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  • (PMID = 23396642.001).
  • [ISSN] 1971-3495
  • [Journal-full-title] Journal of ultrasound
  • [ISO-abbreviation] J Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3478711
  • [Keywords] NOTNLM ; Contrast-enhanced ultrasonography / Diagnosis / Focal nodular hyperplasia / Management / Ultrasonology
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40. Schemmer P, Decker F, Dei-Anane G, Henschel V, Buhl K, Herfarth C, Riedl S: The vital threat of an upper gastrointestinal bleeding: Risk factor analysis of 121 consecutive patients. World J Gastroenterol; 2006 Jun 14;12(22):3597-601
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  • UGI bleeding occurred due to duodenal ulcer (n = 36; 30%), gastric ulcer (n = 35; 29%), esophageal varicosis (n = 12; 10%), Mallory-Weiss syndrome (n = 8; 7%), erosive lesions of the mucosa (n = 20; 17%), cancer (n = 5; 4%), coagulopathy (n = 4; 3%), lymphoma (n = 2; 2%), benign tumor (n = 2; 2%) and unknown reason (n = 1; 1%).

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  • (PMID = 16773718.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4087577
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41. Rubod C, Mubiayi N, Verhulst P, Robert Y, Vinatier D: [Uterine intravenous leiomyomatosis. A case report]. Gynecol Obstet Fertil; 2005 Dec;33(12):991-3
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  • Uterine intravenous leiomyomatosis is a rare benign tumor.
  • The specificity of this tumor is hormonodependency and potential vascular extension.
  • [MeSH-minor] Adult. Female. Humans. Hysterectomy. Neoplasm Invasiveness

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  • (PMID = 16324869.001).
  • [ISSN] 1297-9589
  • [Journal-full-title] Gynécologie, obstétrique & fertilité
  • [ISO-abbreviation] Gynecol Obstet Fertil
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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42. Pata F, Orsini V, Lucisano AM, Pafundi DP, Sacco R: Solitary fibrous tumor of the pelvis: an uncommon soft-tissue tumor. A case report. Ann Ital Chir; 2010 Nov-Dec;81(6):457-60
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  • [Title] Solitary fibrous tumor of the pelvis: an uncommon soft-tissue tumor. A case report.
  • A rare case of Solitary fibrous tumor (SFT) of the pelvis is reported.
  • En bloc excision of tumor and rectum (because of strong adhesions) was performed.
  • SFT is, usually, benign tumor with slow growth and excellent prognosis.

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  • (PMID = 21456483.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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43. Dominical VM, Cavellani CL, Rocha LP, Corrêa RR, Pereira Gde A, Teixeira Vde P: Chagas disease and gynecologic neoplasias. Ann Diagn Pathol; 2010 Oct;14(5):337-40
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  • [Title] Chagas disease and gynecologic neoplasias.
  • The most common benign neoplasm was uterine leiomyoma, and malignant, carcinoma of the cervix.


44. Mackenzie H, Gulati V, Tross S: A rare case of a swollen knee due to disseminated synovial chondromatosis: a case report. J Med Case Rep; 2010;4:113
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  • INTRODUCTION: A synovial chondromatosis is a rare benign neoplasm on the synovium.
  • Although described as a benign disease, it can be very destructive and can cause severe osteoarthritis and pain.
  • CONCLUSIONS: Although synovial chondromatosis is described as a benign disease, it can be very destructive and debilitating.

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  • (PMID = 20416049.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2873448
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45. Liu Y: Benign ovarian and endometrial uptake on FDG PET-CT: patterns and pitfalls. Ann Nucl Med; 2009 Feb;23(2):107-12
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  • [Title] Benign ovarian and endometrial uptake on FDG PET-CT: patterns and pitfalls.
  • Knowledge of benign FDG uptake of the ovaries and uterus is important for daily practice of nuclear medicine radiologists.
  • Benign functional uptake of premenopausal ovaries or uterus is related to the menstrual cycle; therefore, information about the patient's menstrual status is crucial for interpretation.
  • Increased ovarian uptake may also be identified in histologically different benign tumor entities.
  • Nonmenstrual-related endometrial uptake may be present in many benign diseases as well.

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  • (PMID = 19225932.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 41
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46. Biswas D, Crank S: Aetiopathology of maxillary swelling--a 3-year prospective study. Eur Arch Otorhinolaryngol; 2007 Nov;264(11):1295-9
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  • The awareness of the spectrum of pathology related to maxillary swelling is essential for correct diagnosis and treatment.
  • Maxillary swelling was found to be caused by malignant tumours in 54.2%, benign neoplasms in 22.9% and non-neoplastic lesions in 22.9%.
  • Overall squamous cell carcinoma (22.9%) was the commonest lesion, tumour of vascular origin was the commonest benign neoplasm and odontogenic cyst was the commonest among the non-neoplastic lesions.

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  • (PMID = 17611767.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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47. Lersundi A, Mankin HJ, Mourikis A, Hornicek FJ: Chondromyxoid fibroma: a rarely encountered and puzzling tumor. Clin Orthop Relat Res; 2005 Oct;439:171-5
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  • [Title] Chondromyxoid fibroma: a rarely encountered and puzzling tumor.
  • Chondromyxoid fibroma is an uncommon bone neoplasm, accounting in our series for less than 1% of all connective tissue tumors.
  • The tumor is more common in males, and located mostly in the metaphyseal areas of the lower extremity.
  • The tumor is benign and there have been no reports of metastases.
  • The method of treatment that has been used since the initial identification of the tumor has been curettage, which has a 20-25% recurrence rate.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Femur / pathology. Femur / radiography. Femur / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Pelvic Bones / pathology. Pelvic Bones / radiography. Pelvic Bones / surgery. Tibia / pathology. Tibia / radiography. Tibia / surgery. Transplantation, Homologous

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  • (PMID = 16205156.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Klopfleisch R, Klose P, Gruber AD: The combined expression pattern of BMP2, LTBP4, and DERL1 discriminates malignant from benign canine mammary tumors. Vet Pathol; 2010 May;47(3):446-54
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  • [Title] The combined expression pattern of BMP2, LTBP4, and DERL1 discriminates malignant from benign canine mammary tumors.
  • However, their association with tumor malignancy applies only for mean values of large groups of tumors, but no single marker identified to date can be used to reliably predict malignancy for individual tumors.
  • A quantitative real-time reverse transcription polymerase chain reaction array was established to quantify the expression levels of 49 genes relevant to carcinogenesis in laser-microdissected tumor cells of 10 benign and 13 metastatic canine mammary tumors.
  • Seventeen genes with significant (P < .05) differences in gene expression levels between benign and malignant tumors were identified--including ERBB1, SLIT2, progesterone receptor, MIG6, SATB1, and SMAD6--but correct classification of each tumor as benign or malignant was impossible on the basis of any of these genes alone.
  • However, the combined expression patterns of BMP2, LTBP4, and DERL1 (Derlin-1) correctly classified each individual tumor as benign or malignant.
  • This pilot study identified a complex mRNA expression pattern of 3 genes that was able to identify malignancy in laser-microdissected tumor cells for each individual tumor, instead of group means as used in previous studies.
  • [MeSH-minor] Animals. Antigens, Surface / metabolism. BRCA1 Protein / genetics. BRCA1 Protein / metabolism. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Bone Morphogenetic Proteins / genetics. Bone Morphogenetic Proteins / metabolism. Dogs. Female. Gene Expression. Glycoproteins / genetics. Glycoproteins / metabolism. Osteopontin / genetics. Osteopontin / metabolism. Proliferating Cell Nuclear Antigen / genetics. Proliferating Cell Nuclear Antigen / metabolism. Proto-Oncogene Proteins p21(ras) / genetics. Proto-Oncogene Proteins p21(ras) / metabolism. Rad51 Recombinase / genetics. Rad51 Recombinase / metabolism. Receptors, Estrogen / genetics. Receptors, Estrogen / metabolism. Receptors, Progesterone / genetics. Receptors, Progesterone / metabolism. Serpins / genetics. Serpins / metabolism. Telomerase / genetics. Telomerase / metabolism. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Protein p53 / metabolism

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  • (PMID = 20375427.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / BRCA1 Protein; 0 / Biomarkers, Tumor; 0 / Bone Morphogenetic Protein 2; 0 / Bone Morphogenetic Proteins; 0 / Glycoproteins; 0 / Latent TGF-beta Binding Proteins; 0 / Membrane Proteins; 0 / Proliferating Cell Nuclear Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / SERPIN-B5; 0 / Serpins; 0 / Tumor Suppressor Protein p53; 0 / p27 antigen; 106441-73-0 / Osteopontin; 76687-96-2 / teleocalcin; EC 2.7.7.- / Rad51 Recombinase; EC 2.7.7.49 / Telomerase; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras)
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49. Bush LA, Gayle RB, Berkey BD: Multicentric Osteoid Osteoma Presenting a Diagnostic Dilemma. Radiol Case Rep; 2008;3(3):217
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  • We present a case of a relatively common benign tumor that was a diagnostic dilemma because of its atypical appearance in multiple imaging modalities.
  • After biopsy achieved a definite diagnosis, this tumor was successfully treated with radiofrequency ablation of all nidi in one session.

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  • (PMID = 27303550.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4897034
  • [Keywords] NOTNLM ; CT, computed tomography / ESR, ertythrocyte sedimentation rate / MRI, magnetic resonance imaging / WBC, white blood cell
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50. Chen JY, Zeng DS, Yu D, Jin K: [The use of kidney-shaped pressure bandage to prevent postoperative salivary fistula]. Shanghai Kou Qiang Yi Xue; 2010 Apr;19(2):144-6
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  • METHODS: One hundred and ninety-six patients with parotid benign tumor or tumor-like lesions were randomly divided into two groups, 100 cases in the kidney-shaped cotton pad group and 96 cases in the traditional management group.

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  • (PMID = 20485975.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Qi ZH, Li CF, Ma XX, Li ZF, Zhang K, Yu DX: [Changes of 3-tesla 31P-MR spectroscopy of bone and soft tissue tumors]. Zhonghua Zhong Liu Za Zhi; 2009 Jun;31(6):442-6
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  • METHODS: 41 patients were examined by phosphorus surface coil of 3 tesla MR machine, including 18 benign tumor foci and 28 malignant foci, and adjacent normal muscles.
  • RESULTS: The ratios of Pcr/PME and PME/NTP in benign and malignant tumor groups were significantly different from those of the normal group (P<0.05).
  • Between benign and malignant tumor groups, the ratios of PME/beta-ATP and PME/NTP were significantly different (P<0.05).


52. López-Carriches C, Baca-Pérez-Bryan R, Montalvo-Montero S: Schwannoma located in the palate: clinical case and literature review. Med Oral Patol Oral Cir Bucal; 2009 Sep;14(9):e465-8
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  • Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves.

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  • (PMID = 19415055.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 15
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53. Al-Khashnam H, Burezq H, Al-Aradi I, Al-Sabah H, Al-Abdulhadi K: Unusual malignant transformation of recurrent sebaceoma. A case report. Clin Med Oncol; 2008;2:389-92
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  • Sebaceoma is a benign tumor composed of incompletely differentiated sebaceous cells of varying degrees of maturity.
  • The patient had an uneventful postoperative period apart from distal marginal necrosis of the flap, which healed nicely with conservative measures and daily dressing and was sent to our cancer centre to start his adjuvant radiotherapy.Previous literature stated that sebaceoma is a distinctive benign tumor.

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  • [Cites] J Am Acad Dermatol. 2001 Jun;44(6):1004-9 [11369914.001]
  • [Cites] Am J Dermatopathol. 2001 Oct;23(5):456-62 [11801780.001]
  • [Cites] Dermatol Surg. 2003 Jan;29(1):105-7 [12534523.001]
  • [Cites] J Dermatol. 1978 Aug;5(4):139-47 [361778.001]
  • [Cites] Am J Dermatopathol. 2007 Jun;29(3):242-8 [17519621.001]
  • [Cites] Cancer. 1985 Jun 15;55(12):2868-73 [3158388.001]
  • [Cites] Am J Dermatopathol. 1984 Feb;6(1):7-13 [6703260.001]
  • (PMID = 21892304.001).
  • [ISSN] 1177-9314
  • [Journal-full-title] Clinical medicine. Oncology
  • [ISO-abbreviation] Clin Med Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3161692
  • [Keywords] NOTNLM ; malignancy / recurrence / sebaceoma
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54. Gheith S, Boulay R, Cornfield D: Small lymphocytic lymphoma/chronic lymphocytic leukemia in a pelvic myelolipoma. Int J Clin Exp Pathol; 2009;2(1):95-8
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  • Myelolipoma is a rare benign tumor composed of mature adipose tissue and normal hematopoietic elements.
  • The likeliest scenario is that an unusual benign tumor (myelolipoma) was colonized by a relatively common systemic hematopoietic neoplasm SLL/CLL, producing a collision tumor.

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  • [Cites] Ann Clin Lab Sci. 2006 Spring;36(2):208-11 [16682520.001]
  • [Cites] Eur Radiol. 2005 Aug;15(8):1757-9 [15503042.001]
  • [Cites] Diagn Cytopathol. 1999 Jan;20(1):47-51 [9884828.001]
  • [Cites] Am J Clin Pathol. 1992 Mar;97(3):402-4 [1543165.001]
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  • [Cites] Am J Surg Pathol. 1982 Jun;6(4):363-74 [7051876.001]
  • (PMID = 18830383.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Extra adrenal myelolipoma / chronic lymphocytic leukemia / lymphoma / non-Hodgkin lymphoma / small lymphocytic lymphoma
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55. Torres PU: [What are the actual indications for a surgical parathiroidectomy?]. Nephrol Ther; 2005 Dec;1 Suppl 4:S342-50
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  • The chronic stimulation of PTH by these anomalies causes progressive hyperplasia of the parathyroid cells which may be transformed into a benign tumor with a monoclonal appearance.

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  • (PMID = 17373206.001).
  • [ISSN] 1769-7255
  • [Journal-full-title] Néphrologie & thérapeutique
  • [ISO-abbreviation] Nephrol. Ther.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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56. Schlottmann K: [Reader's letter concerning the article by H. Strunk et al. (Fortschr Röntgenstr 2005, 177:900-904). Erroneous diagnosis of liver metastasis as benign tumor in the contrast media aided "Low-MI-Real-Time" sonography with SonoVue]. Rofo; 2005 Dec;177(12):1722-3; author reply 1723
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  • [Title] [Reader's letter concerning the article by H. Strunk et al. (Fortschr Röntgenstr 2005, 177:900-904). Erroneous diagnosis of liver metastasis as benign tumor in the contrast media aided "Low-MI-Real-Time" sonography with SonoVue].
  • [Transliterated title] Leserbrief zum Beitrag H. Strunk et al. (Fortschr Röntgenstr 2005; 177: 900-904). Fehldiagnose einer Lebermetastase als benigner Tumor in der kontrastmittelgestützten "Low-MI-Real-Time"--Sonographie mit SonoVue.

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  • [CommentOn] Rofo. 2005 Jun;177(6):900-2 [15902642.001]
  • (PMID = 16382508.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Comment; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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57. Guzzo M, Locati LD, Prott FJ, Gatta G, McGurk M, Licitra L: Major and minor salivary gland tumors. Crit Rev Oncol Hematol; 2010 May;74(2):134-48
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  • The most common tumor site is the parotid.
  • Nutrition may be a risk factor, as well as irradiation or a long-standing histologically benign tumor that occurs at youth.
  • Signs and symptoms related to major salivary gland tumors differ from those concerning minor salivary gland tumors, as they depend on the different location of the salivary gland.
  • [MeSH-minor] Animals. Digestive System Surgical Procedures / adverse effects. Digestive System Surgical Procedures / methods. Humans. Neoplasm Metastasis. Neoplasm Staging / methods. Prognosis. Recurrence. Salivary Glands, Minor / pathology. Salivary Glands, Minor / surgery

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  • [Copyright] 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19939701.001).
  • [ISSN] 1879-0461
  • [Journal-full-title] Critical reviews in oncology/hematology
  • [ISO-abbreviation] Crit. Rev. Oncol. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 149
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58. Trindade F, Haro R, Requena L: Giant angiolymphoid hyperplasia with eosinophilia on the chest. J Cutan Pathol; 2009 Apr;36(4):493-6
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  • This rare benign process occurs with a female predominance.
  • Whether angiolymphoid hyperplasia with eosinophilia represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, the etiology remains unclear.
  • The lesion is benign but may be persistent and is difficult to eradicate.
  • We report on a case of a 58-year-old Caucasian man who presented a purplish pink dome-shaped tumor of size up to 8 cm in diameter located on the chest.

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  • (PMID = 19278439.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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59. Sakai T, Fujimori M, Tominaga Y, Kanai T, Ito K, Shingu K, Amano J, Kushima H, Tsuchiya S: A case of unilateral gravid macromastia in 23-year-old Japanese woman associated with elevated serum CA19-9. Breast Cancer; 2005;12(3):238-42
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  • This benign tumor is sometimes difficult to distinguish from malignant tumors since it shows few histological characteristics and grows rapidly.
  • Attention is necessary to diagnose tumors of the breast during pregnancy.
  • [MeSH-major] Breast Neoplasms / diagnosis. CA-19-9 Antigen / biosynthesis. Pregnancy Complications, Neoplastic / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Pregnancy

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  • (PMID = 16110297.001).
  • [ISSN] 1340-6868
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / CA-19-9 Antigen
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60. Bewtra C: Fibroadenoma in women in Ghana. Pan Afr Med J; 2009;2:11
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  • BACKGROUND: Fibroadenoma is the commonest benign tumor of female breast.

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  • [Cites] Clin Cancer Res. 2000 Apr;6(4):1422-31 [10778973.001]
  • [Cites] Oncologist. 2006 May;11(5):435-49 [16720843.001]
  • [Cites] Breast J. 2006 Sep-Oct;12(5):451-61 [16958965.001]
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  • (PMID = 21532907.001).
  • [ISSN] 1937-8688
  • [Journal-full-title] The Pan African medical journal
  • [ISO-abbreviation] Pan Afr Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Uganda
  • [Other-IDs] NLM/ PMC2984278
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61. Jung SN, Yim Y, Kwon H: Symmetric lipofibromatous hamartoma affecting digital nerves. Yonsei Med J; 2005 Feb 28;46(1):169-72
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  • Lipofibromatous hamartoma of the nerve is a benign tumor, which affects the major nerves and their branches in the human body.
  • This tumor is often found in young adults and may go through a self- limiting course.
  • However, operation is indicated when the tumor size is large or when the associated nerve compressive symptoms are present.
  • With the aid of a microscope, we dissected and removed the tumor as much as possible without sacrificing the nerve.

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  • [Cites] Pathol Int. 2002 Nov;52(11):730-3 [12685550.001]
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  • (PMID = 15744823.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 11
  • [Other-IDs] NLM/ PMC2823046
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62. Welborn J, Fenner S, Parks R: Angioleiomyoma: a benign tumor with karyotypic aberrations. Cancer Genet Cytogenet; 2010 Jun;199(2):147-8
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  • [Title] Angioleiomyoma: a benign tumor with karyotypic aberrations.

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  • (PMID = 20471520.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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63. Kawata R, Lee K, Araki M, Takenaka H: Safety and usefulness of an electric knife during surgery for parotid benign tumor: postoperative facial paresis and its risk factors. Acta Otolaryngol; 2007 Sep;127(9):966-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Safety and usefulness of an electric knife during surgery for parotid benign tumor: postoperative facial paresis and its risk factors.
  • PATIENTS AND METHODS: In this study, the safety and usefulness of an electric knife in parotid surgery were confirmed by evaluating patients with parotid benign tumor who underwent surgery using an electric knife.
  • The subjects were 135 patients with parotid benign tumors.
  • Depending on the tumor site, transient paresis was observed in 8 of the 13 patients with tumors in the deep lobe but in 28 (22.9%) of the 122 patients with tumors in the superficial lobe.

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  • (PMID = 17712677.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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64. Manjunatha BS, Nagarajappa D: Osteoid osteoma. Indian J Dent Res; 2009 Oct-Dec;20(4):514-5
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  • Osteoid osteoma is a benign tumor of the bone which arises from osteoblasts and is extremely rare in jaws.

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  • (PMID = 20139585.001).
  • [ISSN] 1998-3603
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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65. Huang P, Staerkel G, Sneige N, Gong Y: Fine-needle aspiration of pancreatic serous cystadenoma: cytologic features and diagnostic pitfalls. Cancer; 2006 Aug 25;108(4):239-49
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  • BACKGROUND: The preoperative diagnosis of pancreatic serous cystadenoma (SCA) is important because as a typically benign tumor it can be treated expectantly, whereas many other cystic tumors require excision.
  • This study examines the cytology, clinical and radiologic features, diagnostic accuracy of fine-needle aspiration (FNA), and potential pitfalls associated with this rare tumor.
  • Tumor cells formed loose clusters or monolayered sheets composed of cuboidal cells with indistinct cell borders and granular or clear cytoplasm that was often stripped from the nucleus.
  • Seven (25%) of the aspirates were initially classified as "consistent with SCA," 6 (21%) as "no malignant cells," 3 (11%) as "nondiagnostic specimen," 3 (11%) as "suspicious for malignancy," 3 (11%) as "rare atypical cells," and 6 (21%) as "probably or consistent with mucinous cystic neoplasm."
  • Contaminating GI epithelium and mucin should be distinguished from components of a mucinous neoplasm.

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16691573.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Dilsiz A, Aydin T, Gursan N: Capillary hemangioma as a rare benign tumor of the oral cavity: a case report. Cases J; 2009;2:8622
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  • [Title] Capillary hemangioma as a rare benign tumor of the oral cavity: a case report.
  • INTRODUCTION: Hemangioma is a relatively common benign proliferation of blood vessels that primarily develops during childhood.
  • Early detection and biopsy is necessary to determine the clinical behavior of the tumor and potential dentoalveolar complications.

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  • [Cites] Arch Ophthalmol. 1992 Dec;110(12):1743-7 [1463416.001]
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  • (PMID = 20181211.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827094
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67. Chronopoulos E, Xypnitos FN, Nikolaou VS, Efstathopoulos N, Korres D: Osteoid osteoma of a metacarpal bone: a case report and review of the literature. J Med Case Rep; 2008;2:285
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  • INTRODUCTION: Osteoid osteoma is a benign tumor of the growing skeleton.
  • CONCLUSION: Physicians should be aware of the unusual presence and the atypical clinical presentation of this benign lesion in the metacarpal bones of the hand.

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  • (PMID = 18752665.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2533345
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68. Hayakawa M: [Pleural lipoma: report of a case]. Kyobu Geka; 2005 Dec;58(13):1185-8
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  • Although lipomas are the most common form of the benign neoplasm, occurrence within the thoracic cage is uncommon, and lipomas originating from the pleura are very rare.
  • A chest wall tumor was suspected based on the findings of computed tomography (CT) of the thorax.
  • The tumor was resected by video-assisted thoracoscopic surgery and the patient remains well with no recurrence 4 years postoperatively.
  • The resected tumor was a yellowish pleural mass and the pathological diagnosis was a benign lipoma.

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  • (PMID = 16359024.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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69. Klintworth N, Zenk J, Koch M, Iro H: Postoperative complications after extracapsular dissection of benign parotid lesions with particular reference to facial nerve function. Laryngoscope; 2010 Mar;120(3):484-90
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  • [Title] Postoperative complications after extracapsular dissection of benign parotid lesions with particular reference to facial nerve function.
  • OBJECTIVES/HYPOTHESIS: The desirable extent of surgical intervention for benign parotid tumors remains a matter of controversy.
  • METHODS: We performed a retrospective analysis of the data from patients in whom extracapsular dissection of a benign parotid tumor had been performed under facial nerve monitoring and as a primary intervention in our department between 2000 and 2008.
  • RESULTS: A total of 934 patients were operated on for a newly diagnosed benign tumor of the parotid gland.
  • CONCLUSIONS: Extracapsular dissection of benign parotid tumors is associated with a low rate of postoperative complications, a fact that is confirmed by the available literature.
  • We therefore recommend that use of this technique always be considered as a means of treating benign parotid tumors as conservatively, that is, as uninvasively, as possible.

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  • (PMID = 20112414.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Gupta N, Rajwanshi A, Mohindra S, Vasishta RK, Batra C, Gupta AK: Diagnosis of adult rhabdomyoma by fine needle aspiration cytology: a report of 2 cases. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):968-72
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  • BACKGROUND: Adult rhabdomyoma (ARh) is a rare, benign tumor originating in striated muscle cells.
  • The preoperative correct diagnosis of this tumor is important as it can help in deciding on management.
  • Case 1 was a 43-year-old male who presented with a recurrent tumor in the region of the floor of the mouth.
  • On cytology in both cases, the smears showed numerous large tissue fragments of tumor cells, which were large, polygonal cells with abundant, vacuolated cytoplasm and bland, eccentrically placed nuclei.
  • CONCLUSION: ARh has characteristic cytomorphologic features, which are described in detail in the present report, and they can help in diagnosing this tumor on FNAC.

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  • (PMID = 21053579.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Gajanayake I, Priestnall SL, Benigni L, English K, Summers BA, Garden OA: Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma. J Vet Diagn Invest; 2010 Sep;22(5):775-80
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  • [Title] Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma.
  • Diagnostic investigations revealed total and ionized hypercalcemia and an increased concentration of parathyroid hormone-related peptide.
  • A minority of the neoplastic spindle cells showed positive cytoplasmic parathyroid hormone-related peptide immunostaining.
  • The hypercalcemia resolved following surgery, and the parathyroid hormone-related peptide concentration returned to within the reference interval.
  • The present report describes a previously unreported renal neoplasm causing paraneoplastic hypercalcemia and highlights the possibility of paraneoplastic hypercalcemia being caused by a benign neoplasm.

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  • (PMID = 20807942.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Hayashi T, Kawahara H, Yoshimoto K, Kashiwagi H, Yanaga K, Komine K: Early cystoadenocarcinoma of vermiform appendix simulating submucosal tumor of the cecum. Int J Surg; 2008 Dec;6(6):e15-7
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  • [Title] Early cystoadenocarcinoma of vermiform appendix simulating submucosal tumor of the cecum.
  • A submucosal tumor with a maximum diameter of 5cm was detected in the cecum.
  • The tissue of the submucosal tumor was not obtained by endoscopic biopsy, and tumor diagnosis could not be confirmed by this method.
  • Because the tumor was too large to be a benign tumor, we were able to conclude it was malignant.
  • As the swollen vermiform appendix pressed the cecum extraluminally, endoscopic examination indicated the possibility of submucosal tumor.
  • Postoperative pathological diagnosis was cystoadenocarcinoma, the tumor was extended within the mucosal layer, and no lymph node metastasis was detected.

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  • (PMID = 19059125.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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73. Rodallec MH, Feydy A, Larousserie F, Anract P, Campagna R, Babinet A, Zins M, Drapé JL: Diagnostic imaging of solitary tumors of the spine: what to do and say. Radiographics; 2008 Jul-Aug;28(4):1019-41
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  • Hemangioma is the most common benign tumor of the spine.
  • The diagnosis of spinal tumors is based on patient age, topographic features of the tumor, and lesion pattern as seen at CT and MR imaging.
  • In the remaining cases, the differential diagnosis may include other primary spinal tumors, vertebral metastases and major nontumoral lesions simulating a vertebral tumor, Paget disease, spondylitis, echinococcal infection, and aseptic osteitis.


74. Gasparre G, Hervouet E, de Laplanche E, Demont J, Pennisi LF, Colombel M, Mège-Lechevallier F, Scoazec JY, Bonora E, Smeets R, Smeitink J, Lazar V, Lespinasse J, Giraud S, Godinot C, Romeo G, Simonnet H: Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet; 2008 Apr 1;17(7):986-95
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  • [Title] Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
  • Here we show a benign tumor type in which mtDNA mutations that lead to complex I (CI) enzyme deficiency are found in all tumors and are the only genetic alteration detected.

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  • (PMID = 18156159.001).
  • [ISSN] 1460-2083
  • [Journal-full-title] Human molecular genetics
  • [ISO-abbreviation] Hum. Mol. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / Electron Transport Chain Complex Proteins; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / RNA, Messenger; EC 1.6.5.3 / Electron Transport Complex I; EC 1.6.99.3 / NADH Dehydrogenase; EC 2.3.3.1 / Citrate (si)-Synthase; EC 2.7.7.- / POLG protein, human; EC 2.7.7.7 / DNA-Directed DNA Polymerase; IY9XDZ35W2 / Glucose
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75. Saetti R, Silvestrini M, Narne S: Ethmoid osteoma with frontal and orbital extension: endoscopic removal and reconstruction. Acta Otolaryngol; 2005 Oct;125(10):1122-5
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  • Endoscopy provides a safe and effective way of treating craniofacial bony benign lesions.
  • It is the most frequent benign neoplasm of the nose and paranasal sinuses.
  • [MeSH-minor] Adult. Endoscopy. Female. Frontal Bone / pathology. Frontal Bone / surgery. Humans. Neoplasm Invasiveness. Orbit / pathology. Orbit / surgery. Reconstructive Surgical Procedures

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  • (PMID = 16298798.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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76. Paşaoğlu O, Ciftçi E, Tel N, Ozalp S, Acikalin MF: Benign clear cell adenofibroma of the ovary. A case report with literature review. Gynecol Obstet Invest; 2007;64(1):36-9
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  • [Title] Benign clear cell adenofibroma of the ovary. A case report with literature review.
  • Most clear cell neoplasms of the ovaries are carcinomas; benign and borderline clear cell tumors are uncommon.
  • To date, only 12 cases of benign clear cell adenofibroma have been reported in the literature.
  • Here we report a case of benign clear cell adenofibroma of the left ovary in a 51-year-old postmenopausal woman.
  • In this article we discussed the criteria for the diagnosis of benign and borderline clear cell adenofibromas and reviewed the literature.
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Humans. Hysterectomy / methods. Immunohistochemistry. Middle Aged. Neoplasm Staging. Ovariectomy / methods. Pelvic Pain / diagnosis. Pelvic Pain / etiology. Postmenopause. Risk Assessment. Treatment Outcome. Uterine Hemorrhage / diagnosis. Uterine Hemorrhage / etiology


77. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.
  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).

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  • (PMID = 21938165.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168018
  • [Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum
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78. Liess BD, Lane RV, Frazier S, Zitsch RP 3rd: Bilateral canalicular adenoma of the parotid gland. Arch Otolaryngol Head Neck Surg; 2006 Mar;132(3):339-41
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  • Canalicular adenoma is a rare benign salivary gland tumor that occurs almost exclusively in the upper lip.
  • Rarely, this benign tumor may occur multifocally in the oral cavity.
  • We report a case of canalicular adenoma in bilateral parotid glands, discuss histological characteristics, and review this tumor.

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  • (PMID = 16549756.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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79. Lee SY, Lee SJ, Lee CS, Lee KR: Aneurysmal bone cyst originating from the first rib. Am J Surg; 2008 Jan;195(1):104-5
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  • Aneurysmal bone cyst is a benign tumor of the skeletal system and rare in the ribs.
  • The first rib containing tumor was removed.

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  • (PMID = 18082549.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Slesarenko YA, Sampson SP, Gould ES, Dagum AB: Recurrent enchondroma protuberans: a case report. J Hand Surg Am; 2005 Nov;30(6):1318-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Enchondroma protuberans is a rare benign tumor.
  • [MeSH-major] Bone Neoplasms / pathology. Chondroma / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 16344196.001).
  • [ISSN] 0363-5023
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Swamy GG, Satyanarayana N: Clinicopathological analysis of ovarian tumors--a study on five years samples. Nepal Med Coll J; 2010 Dec;12(4):221-3
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  • Among 120 cases, majority 86 (71.6%) were benign, but alarming number 30 (25.0%) were malignant, remaining 4 cases were borderline.
  • The commonest benign tumor was serous cyst adenoma, while; the commonest malignant tumors were granulosa cell tumor and endometrial carcinoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Cystadenoma, Serous / pathology. Epithelium / surgery. Female. Granulosa Cell Tumor / pathology. Humans. Middle Aged. Young Adult

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  • (PMID = 21744762.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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82. Zaravinos A, Spandidos DA: Yin yang 1 expression in human tumors. Cell Cycle; 2010 Feb 1;9(3):512-22
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  • The mechanisms of YY1 action are related to its ability to initiate, activate or repress transcription depending on the context in which it binds.
  • Moreover, we concentrate on the most relevant studies that have focused on YY1 regulation. we performed computational analysis on thirty-six publicly available Gene expression Omnibus (GeO) datasets, to further understand whether differences in YY1 transcript levels occur in different cancer types when compared with relative normal tissue, benign tumor or its metastatic counterpart.
  • Our results suggest a dual role of YY1 in cancer development, either through overexpression or under-expression, depending on the tumor type.

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  • (PMID = 20081375.001).
  • [ISSN] 1551-4005
  • [Journal-full-title] Cell cycle (Georgetown, Tex.)
  • [ISO-abbreviation] Cell Cycle
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / YY1 Transcription Factor
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83. Martins MD, Anunciato de Jesus L, Fernandes KP, Bussadori SK, Taghloubi SA, Martins MA: Intra-oral schwannoma: case report and literature review. Indian J Dent Res; 2009 Jan-Mar;20(1):121-5
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  • Schwannoma is a relatively uncommon, slow-growing benign tumor that is derived apparently from the Schwann cells.
  • Usually, this lesion is not taken into account during clinical practice and the differential diagnosis includes numerous benign neoformations based on epithelial and connective tissues.

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  • (PMID = 19336874.001).
  • [ISSN] 1998-3603
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 23
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84. Akhaddar A, Albouzidi A, Elmostarchid B, Gazzaz M, Boucetta M: Sudden onset of paraplegia caused by hemorrhagic spinal epidural angiolipoma. A case report. Eur Spine J; 2008 Sep;17 Suppl 2:S296-8
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  • Spinal epidural angiolipoma is a rare benign tumor containing vascular and mature adipose elements.
  • A slow progressive clinical course was mostly presented and rarely a fluctuating course during pregnancy.
  • A bilateral T2-T4 laminectomy was performed to achieve resection of a lipomatous tumor containing area of spontaneous hemorrhage.
  • Histologic examination revealed the tumor as an angiolipoma.

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  • [Cites] Neurochirurgie. 2000 Dec;46(6):523-533 [11148405.001]
  • [Cites] Acta Neurochir (Wien). 2004 Mar;146(3):299-302; discussion 302 [15015054.001]
  • [Cites] Neurosurgery. 1985 Mar;16(3):406-11 [3982624.001]
  • [Cites] J Neurosurg. 2005 Aug;103(2 Suppl):166-9 [16370284.001]
  • [Cites] J Neurosurg. 1993 Feb;78(2):280-6 [8421211.001]
  • [Cites] Spine (Phila Pa 1976). 1997 Oct 1;22(19):2304-8 [9346153.001]
  • [Cites] AJNR Am J Neuroradiol. 1999 Aug;20(7):1365-72 [10472999.001]
  • [Cites] Surg Neurol. 1990 Sep;34(3):173-8 [2201098.001]
  • (PMID = 18228054.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2525899
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85. Utermark T, Kaempchen K, Antoniadis G, Hanemann CO: Reduced apoptosis rates in human schwannomas. Brain Pathol; 2005 Jan;15(1):17-22
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  • Schwannomas, tumors originating from Schwann cells, represent a frequent neurological tumor and can occur both in a genetic disorder called neurofibromatosis type 2 (NF2) and sporadically.
  • In both cases the genetic background is identical as all schwannomas are caused by biallelic mutations in the tumor suppressor gene NF2 coding for merlin.
  • Here, we report in vivo and in vitro evidence that the basal apoptosis rate of primary human schwannoma cells is reduced in comparison to that of normal Schwann cells, supporting the idea that in this benign tumor type, apoptosis has a role in tumorigenesis.

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  • (PMID = 15779232.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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86. Chen JF, Zhang LJ, Zhao AL, Wang Y, Wu N, Xiong HC, Liang Z, Li JY, Huang XF, Yang Y: [Abnormal expression of Thy-1 as a novel tumor marker in lung cancer and its prognostic significance]. Zhonghua Yi Xue Za Zhi; 2005 Jul 20;85(27):1921-5
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  • [Title] [Abnormal expression of Thy-1 as a novel tumor marker in lung cancer and its prognostic significance].
  • METHODS: In this study, we used anti-Thy-1/CD90 antibody to detect the expression pattern of Thy-1 in different lung tumor sections, which were embedded in paraffin blocks.
  • CONCLUSION: There is a significant overexpressed Thy-1 located in lung cancer cell nucleus as compared to the normal tissue or benign tumor cells of lung, and it is one of the factors effected on the prognosis of NSCLC patients.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Female. Humans. Lung / metabolism. Lung / pathology. Male. Middle Aged. Neoplasm Staging. Prognosis. Tumor Suppressor Protein p53 / metabolism

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  • (PMID = 16255990.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Thy-1; 0 / Biomarkers, Tumor; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53
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87. Brodsky JR, Kim DY, Jiang Z: Cervical lipoblastoma: case report, review of literature, and genetic analysis. Head Neck; 2007 Nov;29(11):1055-60
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  • BACKGROUND: Lipoblastoma is a rare, benign tumor of infants and children, usually occurring in the extremities and trunk, with only a few cases reported in the neck.
  • MRI can be helpful in identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor.

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  • (PMID = 17427967.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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88. Choi SW, Song SH: Intrapelvic lipoblastoma with massive spinal canal invasion. Childs Nerv Syst; 2007 May;23(5):581-5
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  • OBJECTS: The lipoblastoma is a rare benign pediatric neoplasm that derives from embryonic white fat cells.
  • However, this tumor with spinal invasion in children is extremely rare.
  • CONCLUSION: Lipoblastoma is a rare benign neoplasm and lumbosacral invasion is unique.

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  • [Cites] Pediatr Surg Int. 2000;16(5-6):458-61 [10955594.001]
  • [Cites] Am J Surg Pathol. 1997 Oct;21(10):1131-7 [9331284.001]
  • [Cites] Pediatrics. 2000 Jan;105(1 Pt 1):123-8 [10617716.001]
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  • (PMID = 17143644.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Coloring Agents
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89. Loo WT, Tong JM, Cheung MN, Chow LW: A new predictive and prognostic marker (ATP bioluminescence and positron emission tomography) in vivo and in vitro for delivering adjuvant treatment plan to invasive breast tumor patients. Biomed Pharmacother; 2006 Jul;60(6):285-8
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  • [Title] A new predictive and prognostic marker (ATP bioluminescence and positron emission tomography) in vivo and in vitro for delivering adjuvant treatment plan to invasive breast tumor patients.
  • In this preliminary study, the cell proliferation rate of normal (N=45), benign (N=29) and invasive breast tumor tissue (N=70) has been quantified in vitro by ATP bioluminescence assay.
  • Next, individual prognostic factor (tumor grades, lymph node involvement, estrogen and progesterone receptor and HER-2 status) has been correlated with the level of metabolic rate (ATP).
  • The results showed that invasive tumor had the highest level of ATP bioluminescence compared with that of benign tumor (mean difference=1.97) and the normal breast tissue (mean difference=2.75).

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  • (PMID = 16860527.001).
  • [ISSN] 0753-3322
  • [Journal-full-title] Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie
  • [ISO-abbreviation] Biomed. Pharmacother.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 8L70Q75FXE / Adenosine Triphosphate; EC 2.7.10.1 / Receptor, ErbB-2
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90. Xu AM, Zhang SH, Zheng JM, Zheng WQ, Wu MC: Pathological and molecular analysis of sporadic hepatic angiomyolipoma. Hum Pathol; 2006 Jun;37(6):735-41
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  • We sought to better define the morphological variations and immunohistochemical and molecular features of this unusual tumor.
  • Most of the tumor cells were positive for HMB-45 (100%) and SMA (100%).
  • Hepatic AML is a benign neoplasm with varied morphology and monoclonal growth.
  • Neither LOH nor MSI appears to play an important role in the pathogenesis of this tumor.
  • [MeSH-major] Angiomyolipoma / genetics. Angiomyolipoma / pathology. Biomarkers, Tumor / analysis. Liver Neoplasms / genetics. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antigens, Neoplasm / analysis. Chromosomes, Human, X. Clone Cells. DNA, Neoplasm / analysis. Female. Hepatectomy. Humans. Immunohistochemistry. Lasers. Male. Melanoma-Specific Antigens. Microdissection. Middle Aged. Muscle, Smooth / cytology. Muscle, Smooth / metabolism. Neoplasm Proteins / analysis. Prospective Studies. Receptors, Androgen / metabolism. Sex Chromosome Aberrations. Tumor Burden

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  • (PMID = 16733215.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Receptors, Androgen
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91. Albisinni U, Rimondi E, Malaguti MC, Ciminari R, Bianchi G, Mercuri M: Radiofrequency thermal ablation of non spinal osteoid osteoma: remarks on method. Radiol Med; 2005 May-Jun;109(5-6):555-62
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  • Osteoid osteoma is a small benign tumor, with a ''nidus'' that rarely exceeds 15 mm in diameter.

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  • (PMID = 15973230.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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92. Birman MV, McHugh JB, Hayden RJ, Jebson PJ: Pilomatrixoma of the forearm: a case report. Iowa Orthop J; 2009;29:121-3
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  • Pilomatrixoma is a benign neoplasm derived from hair follicle matrix cells.

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  • [Cites] Int J Pediatr Otorhinolaryngol. 2001 Feb;57(2):123-8 [11165649.001]
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  • (PMID = 19742099.001).
  • [ISSN] 1555-1377
  • [Journal-full-title] The Iowa orthopaedic journal
  • [ISO-abbreviation] Iowa Orthop J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC2723706
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93. Lü J, Zou J, Wu H, Cai L: Compensative shuttling of merlin to phosphorylation on serine 518 in vestibular schwannoma. Laryngoscope; 2008 Jan;118(1):169-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Vestibular schwannoma (VS) is a benign tumor with malignant biological consequence because of its special location, and its occurrence is highly related to merlin.
  • METHODS: To confirm endogenous merlin protein expression in abiogenous VS cells, in situ hybridization, immunohistochemistry, and Western blot was performed in tumor tissues surgically resected from patients.
  • CONCLUSION: In line with the pathologic characteristic of VS as a benign tumor, merlin compensates for the malignant effect of S518 phosphorylation by limiting the loss of contact inhibition of growth and controlling proliferation.


94. Magro G: Mammary myofibroblastoma: a tumor with a wide morphologic spectrum. Arch Pathol Lab Med; 2008 Nov;132(11):1813-20
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  • [Title] Mammary myofibroblastoma: a tumor with a wide morphologic spectrum.
  • CONTEXT: Myofibroblastoma (MFB) of the breast is an unusual benign tumor that belongs to the family of the "benign spindle cell tumors of the mammary stroma."
  • Since MFB may show alarming morphologic features, which can lead to a misdiagnosis of malignancy, histologic figures of this tumor, including its more unusual variants, are provided to offer pathologists a practical approach to a correct diagnosis.
  • Histogenesis and pathogenesis of this tumor are also proposed.
  • Accordingly, this unusual benign tumor may represent a potential diagnostic pitfall, especially when interpreting fine-needle aspiration and/or needle core biopsy.

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  • (PMID = 18976021.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 109
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95. Miyake M, Tateishi U, Maeda T, Arai Y, Hasegawa T, Sugimura K: Bronchial granular cell tumor: a case presenting secondary obstructive changes on CT. Radiat Med; 2006 Feb;24(2):154-7
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  • [Title] Bronchial granular cell tumor: a case presenting secondary obstructive changes on CT.
  • Bronchial granular cell tumor is an uncommon benign tumor that causes pulmonary complications due to obstruction of the airways.
  • [MeSH-major] Bronchial Neoplasms / complications. Granular Cell Tumor / complications. Lung Diseases, Obstructive / etiology

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  • (PMID = 16715680.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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96. Ahmad R, Ishlah W, Azilah N, Rahman JA: Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Asian J Surg; 2008 Oct;31(4):174-8
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males.

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  • (PMID = 19010758.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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97. Sakamoto A, Yoshida T, Matsuura S, Tanaka K, Matsuda S, Oda Y, Hori Y, Yokomizo A, Iwamoto Y: Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features. World J Surg Oncol; 2007;5:88
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  • Metastatic RCC must be differentiated from benign primary soft-tissue tumors because aggressive surgical resection is necessary.
  • Because the growth of the lesion was slow, benign tumor was a differential diagnosis.
  • CONCLUSION: MRI features of metastatic RCC may be beneficial in differentiating it from primary soft-tissue tumor.

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  • [Cites] AJR Am J Roentgenol. 2000 Jun;174(6):1623-8 [10845496.001]
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  • (PMID = 17683570.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1976113
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98. Bozzo C, Garrel R, Meloni F, Stomeo F, Crampette L: Endoscopic treatment of antrochoanal polyps. Eur Arch Otorhinolaryngol; 2007 Feb;264(2):145-50
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  • The antrochoanal polyp (Killian polyp) is an infrequent, benign neoplasm, which arises from the maxillary sinus to reach the ipsilateral choana.
  • [MeSH-minor] Adolescent. Adult. Child. Eosinophilia / epidemiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

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  • (PMID = 17013627.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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99. Yamaguchi M, Yagi K, Ikeya E, Fujimura T, Taguchi J, Shibuya M, Inamura S, Kanabuchi K: A case report of papillary fibroelastoma attached to chorda tendineae of mitral valve. Tokai J Exp Clin Med; 2006 Jul;31(2):56-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We diagnosed him as ischemic heart disease and doubt of heart tumor.
  • We dissected the tumor together with one chorda tendineae of mitral valve, and a performed aorta - coronary bypass surgery.
  • We diagnosed the tumor as papillary fibroelastoma by pathological diagnosis.
  • Papillary fibroelastoma is extremely rare with 7-9% of benign tumor of heart primary.
  • The tumor is benign, but there is a problem to cause embolism.
  • Therefore, when we discovered papillary fibroelastoma, surgical resection of the tumor is the first-line therapy.
  • Papillary fibroelastoma is benign tumor, but the pathological characteristic is still unidentified.

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  • (PMID = 21302223.001).
  • [ISSN] 2185-2243
  • [Journal-full-title] The Tokai journal of experimental and clinical medicine
  • [ISO-abbreviation] Tokai J. Exp. Clin. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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100. Li NY, Zhou XJ, Jin XZ, Meng K, Ma HH, Zheng XG, Jiang SJ, Sun GQ: [A clinicopathologic study of dysembryoplstic neuroepithelial tumor]. Zhonghua Bing Li Xue Za Zhi; 2005 Sep;34(9):561-5
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  • [Title] [A clinicopathologic study of dysembryoplstic neuroepithelial tumor].
  • OBJECTIVE To study the clinicopathologic features, radiologic findings, treatment modalities and prognosis of dysembryoplastic neuroepithelial tumor (DNT).
  • On magnetic resonance imaging (MRI) study, the tumor was hypodense on T1 and hyperdense on T2.
  • None of the cases showed tumor recurrence after operation.
  • The tumor was formed by an admixture of oligodendrocyte-like cells, mature neurons and astrocytes, with obvious microcystic changes.
  • CONCLUSIONS: DNT is a benign tumor (corresponding to WHO grade I) that can be cured by surgical excision, despite sometimes incomplete tumor removal.

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
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  • (PMID = 16468305.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Neurofilament Proteins; 0 / S100 Proteins; 0 / Synaptophysin
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