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1. Owonikoko T, Agha M, Balassanian R, Smith R, Raptis A: Gemtuzumab therapy for isolated extramedullary AML relapse following allogeneic stem-cell transplant. Nat Clin Pract Oncol; 2007 Aug;4(8):491-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ten months following repeat transplant, the patient presented with an increasing number of extramedullary sites of biopsy-proven disease relapse (i.e. cranial and peripheral nerves, tongue, abdominal wall and chest wall).
  • INVESTIGATIONS: Physical examination, complete blood count, BM biopsy, flow cytometry, cytogenetic analysis, chimera study, tongue biopsy, abdominal-wall biopsy, cytology and immunohistochemistry, CT scan of the chest, abdomen and pelvis, MRI of the brain, and cerebrospinal fluid analysis.
  • DIAGNOSIS: Isolated extramedullary relapse of acute myeloid leukemia after stem-cell transplant.
  • [MeSH-major] Aminoglycosides / therapeutic use. Antibodies, Monoclonal / therapeutic use. Antineoplastic Agents / therapeutic use. Hematopoietic Stem Cell Transplantation / adverse effects. Neoplasm Recurrence, Local / drug therapy. Sarcoma, Myeloid / drug therapy

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  • (PMID = 17657254.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Aminoglycosides; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; 0 / gemtuzumab
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2. Zhang Y, Xie H, Zhu K: [Introduction and advantage analysis of the stepwise method for the construction of vascular trees]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2010 Aug;27(4):902-6
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  • In order to compare the CCO method and stepwise method proposed here, two 3D arterial trees of human tongue were grown with their vascular tree having a special structure.
  • Based on the corrosion casts of real arterial tree of human tongue, the data about the two trees constructed by different methods were compared and analyzed, including the averaged segment diameters at respective levels, the distribution and the diameters of the branches of first level at respective directions.
  • The results show that the vascular tree built by stepwise method is more similar to the true arterial of human tongue when compared against the tree built by CCO method.

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  • (PMID = 20842868.001).
  • [ISSN] 1001-5515
  • [Journal-full-title] Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
  • [ISO-abbreviation] Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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3. Bruening D, Richards JG: Optimal ankle axis position for articulated boots. Sports Biomech; 2005 Jul;4(2):215-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We also calculated the amount of anterior skin movement that a boot tongue must account for during a full range of ankle motion.
  • The expansion required by the boot tongue had a moderate association with foot length and low variability (r = 0.58, standard error of estimate = 0.07 mm).
  • An expandable tongue will accommodate full plantar flexion and reduce pressure on the anterior ankle during dorsiflexion, eliminating common pressure-related injuries.

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  • (PMID = 16138658.001).
  • [ISSN] 1476-3141
  • [Journal-full-title] Sports biomechanics
  • [ISO-abbreviation] Sports Biomech
  • [Language] ENG
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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4. Isayama R, Shiga K, Tanaka E, Itsukage M, Tokuda T, Nakagawa M: [A rare complication of dysarthria in a patient with inclusion body myositis: a case report]. Rinsho Shinkeigaku; 2010 Oct;50(10):695-9
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  • His neurological examination revealed muscle atrophy and weakness in the tongue, the forearm flexors, and the vastus medialis muscles.
  • A biopsy from vastus lateralis muscle showed variation in fiber size, infiltration of mononucleated cells, and numerous fibers with rimmed vacuoles, leading to the diagnosis of definite inclusion body myositis.
  • The EMG findings of the tongue demonstrated low amplitude motor unit potentials during voluntary contraction, abundant fibrillation potentials at rest, and preserved interference pattern at maximal contraction, implying myogenic changes.
  • We surmised the dysarthria seen in this patient, an atypical clinical feature in IBM, presumably caused by muscle involvement in the tongue muscle.

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  • (PMID = 21061547.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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5. Oliven A, Tov N, Geitini L, Steinfeld U, Oliven R, Schwartz AR, Odeh M: Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients. Eur Respir J; 2007 Oct;30(4):748-58
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  • The purpose of the present study was to quantify the mechanical effect of genioglossus stimulation on flow mechanics and pharyngeal cross-sectional area in patients with obstructive sleep apnoea, and to identify variables that determine the magnitude of the respiratory effect of tongue protrusion.
  • The pharyngeal response to genioglossus stimulation was related to the magnitude of advancement of the posterior side of the tongue, but not to the severity of sleep apnoea, critical pressure, compliance or the shape and other characteristics of the velopharynx.
  • The response to genioglossus stimulation depends upon the magnitude of tongue protrusion achieved rather than on inherent characteristics of the patient and their airway.
  • [MeSH-minor] Adult. Electric Stimulation Therapy. Electroencephalography / methods. Electrooculography / methods. Humans. Male. Middle Aged. Models, Anatomic. Muscles / pathology. Oxygen / metabolism. Pharyngeal Muscles / metabolism. Polysomnography / methods. Pressure. Tongue / anatomy & histology

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  • (PMID = 17567673.001).
  • [ISSN] 0903-1936
  • [Journal-full-title] The European respiratory journal
  • [ISO-abbreviation] Eur. Respir. J.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL37379; United States / NHLBI NIH HHS / HL / HL50381
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] S88TT14065 / Oxygen
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6. Adachi T, Huxtable AG, Fang X, Funk GD: Substance P modulation of hypoglossal motoneuron excitability during development: changing balance between conductances. J Neurophysiol; 2010 Aug;104(2):854-72
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  • Hypoglossal (XII) MNs innervate tongue protruder muscles and participate in several behaviors that must be functional from birth including swallowing, suckling and breathing.

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  • (PMID = 20538779.001).
  • [ISSN] 1522-1598
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Neurokinin-1; 0 / Sodium Channel Blockers; 33507-63-0 / Substance P; 4368-28-9 / Tetrodotoxin; 9NEZ333N27 / Sodium; EC 2.3.1.6 / Choline O-Acetyltransferase
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7. Medeiros AP, Ferreira JT, Felício CM: Correlation between feeding methods, non-nutritive sucking and orofacial behaviors. Pro Fono; 2009 Oct-Dec;21(4):315-9
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  • The duration of breastfeeding was positively correlated with the mobility of the tongue and jaw (p = 0.05).

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  • (PMID = 20098950.001).
  • [ISSN] 1809-399X
  • [Journal-full-title] Pró-fono : revista de atualização científica
  • [ISO-abbreviation] Pro Fono
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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8. Azman BZ, Ankathil R, Siti Mariam I, Suhaida MA, Norhashimah M, Tarmizi AB, Nor Atifah MA, Kannan TP, Zilfalil BA: Cytogenetic and clinical profile of Down syndrome in Northeast Malaysia. Singapore Med J; 2007 Jun;48(6):550-4
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  • The prominent craniofacial features noted were upslanting palpebral fissures (89.3 percent), flat facial profile (64.9 percent), low set ears (56.1 percent), epicanthic folds (17.5 percent) and protruding tongue (19.2 percent).
  • CONCLUSION: Efforts to establish early diagnosis and a proper screening for high association with systemic anomalies should be undertaken among the Down syndrome patients in this population.

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  • (PMID = 17538755.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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9. Rebol J: The vascularisation of oral cavity tumours and tumour shell tissue determined by three-dimensional power Doppler sonography. Ultrasound Med Biol; 2007 Apr;33(4):493-9
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  • [Title] The vascularisation of oral cavity tumours and tumour shell tissue determined by three-dimensional power Doppler sonography.
  • The investigation was carried out preoperatively on 49 patients with squamous carcinoma of the tongue and floor of the mouth.
  • The vascularity of oral cavity tumours was determined in 4 mm and 7 mm shells surrounding the tumour.
  • The difference between vascularity indices VI and VFI of peritumorous tissue and tumour was also varied significantly between N0 and N+ neck (p < 0.05) and was higher in N+ tumours.
  • Tumours which had metastasised showed richer vascularity in their shells and a greater difference in vascularity between the shell and tumour tissue.
  • [MeSH-minor] Adult. Aged. Female. Humans. Image Interpretation, Computer-Assisted. Lymphatic Metastasis. Male. Middle Aged. Neck. Neoplasm Staging. Statistics, Nonparametric. Ultrasonography, Doppler

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  • (PMID = 17316963.001).
  • [ISSN] 0301-5629
  • [Journal-full-title] Ultrasound in medicine & biology
  • [ISO-abbreviation] Ultrasound Med Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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10. Zaidi FN, Krimm RF, Whitehead MC: Exuberant neuronal convergence onto reduced taste bud targets with preservation of neural specificity in mice overexpressing neurotrophin in the tongue epithelium. J Neurosci; 2007 Dec 12;27(50):13875-81
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  • [Title] Exuberant neuronal convergence onto reduced taste bud targets with preservation of neural specificity in mice overexpressing neurotrophin in the tongue epithelium.

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  • (PMID = 18077699.001).
  • [ISSN] 1529-2401
  • [Journal-full-title] The Journal of neuroscience : the official journal of the Society for Neuroscience
  • [ISO-abbreviation] J. Neurosci.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC007176; United States / NIDCD NIH HHS / DC / R01 DC01091
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fluorescent Dyes; 0 / Nerve Growth Factors; 147336-22-9 / Green Fluorescent Proteins
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11. Breza JM, Nikonov AA, Contreras RJ: Response latency to lingual taste stimulation distinguishes neuron types within the geniculate ganglion. J Neurophysiol; 2010 Apr;103(4):1771-84
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  • EGG) from the anterior tongue to signal when the stimulus contacted the lingual epithelium.

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  • (PMID = 20107132.001).
  • [ISSN] 1522-1598
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC-00044; United States / NIDCD NIH HHS / DC / DC-004785
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 2968PHW8QP / Citric Acid; 451W47IQ8X / Sodium Chloride; 57-50-1 / Sucrose; 660YQ98I10 / Potassium Chloride; A7V27PHC7A / Quinine
  • [Other-IDs] NLM/ PMC2853290
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12. Lorier AR, Funk GD, Greer JJ: Opiate-induced suppression of rat hypoglossal motoneuron activity and its reversal by ampakine therapy. PLoS One; 2010 Jan 19;5(1):e8766
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  • BACKGROUND: Hypoglossal (XII) motoneurons innervate tongue muscles and are vital for maintaining upper-airway patency during inspiration.

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  • [Cites] Clin Exp Pharmacol Physiol. 2000 Jan-Feb;27(1-2):132-7 [10696542.001]
  • (PMID = 20098731.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCAAT-Binding Factor; 0 / Nfyb protein, mouse; 100929-53-1 / Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
  • [Other-IDs] NLM/ PMC2808240
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13. Larsen SR, Johansen J, Sørensen JA, Krogdahl A: The prognostic significance of histological features in oral squamous cell carcinoma. J Oral Pathol Med; 2009 Sep;38(8):657-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim was to assess the prognostic value of histological features related to the primary tumour.
  • RESULTS: The predominant sites were floor of mouth (FOM, 39%) and lateral tongue (35%).
  • Nodal involvement at diagnosis was observed in 36% which was significantly related to grade, neural and vascular invasion; surgical margins and increasing tumour depth.
  • A cut-off value of 2 mm (4 mm for FOM) separated patients without and with nodal metastasis at the time of diagnosis.
  • However, on multivariate analysis, neck disease was only associated with tumour depth and grade.
  • Cox analysis of local recurrence in the oral cavity over time showed that tumour diameter and surgical margins were significant predictors while cause-specific survival was related to diameter, depth of invasion, surgical margins and extracapsular spread (ECS).
  • CONCLUSIONS: Tumour depth and grade were strong prognostic factors for nodal metastasis, independently of other histological features.
  • Tumour diameter and margins independently predict local recurrences in the oral cavity as well as cause-specific survival.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Combined Modality Therapy. Female. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Predictive Value of Tests. Prognosis. Proportional Hazards Models. Sex Distribution. Statistics, Nonparametric. Survival Analysis. Young Adult


14. Patterson JM, Hildreth A, Wilson JA: Measuring edema in irradiated head and neck cancer patients. Ann Otol Rhinol Laryngol; 2007 Aug;116(8):559-64
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  • Lower levels of agreement were found for the tongue base, valleculae, pharyngeal walls, and anterior commissure.
  • [MeSH-major] Edema / diagnosis. Laryngeal Edema / diagnosis. Otorhinolaryngologic Neoplasms / radiotherapy. Pharyngeal Diseases / diagnosis. Radiation Injuries / diagnosis
  • [MeSH-minor] Adult. Aged. Dose Fractionation. Female. Follow-Up Studies. Humans. Laryngoscopy. Larynx / radiation effects. Male. Middle Aged. Neoplasm Staging. Observer Variation. Pharynx / radiation effects. Prospective Studies. Radioisotope Teletherapy. Reference Values. Video Recording

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  • (PMID = 17847721.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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15. Tanaka R, Ariyama H, Qin B, Takii Y, Baba E, Mitsugi K, Harada M, Nakano S: In vitro schedule-dependent interaction between paclitaxel and oxaliplatin in human cancer cell lines. Cancer Chemother Pharmacol; 2005 Jun;55(6):595-601
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  • PURPOSE: In order to define the most effective administration schedule of the combination of paclitaxel and oxaliplatin, we investigated the in vitro interaction between these drugs in a panel of three human cancer cell lines (AZ-521 gastric adenocarcinoma cell line, HST-1 tongue squamous carcinoma cell line, and KSE-1 esophageal squamous carcinoma cell line).
  • [MeSH-minor] Cell Line, Tumor. Cell Survival / drug effects. Drug Administration Schedule. Drug Screening Assays, Antitumor. Drug Synergism. Flow Cytometry. Humans

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  • (PMID = 15731917.001).
  • [ISSN] 0344-5704
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; P88XT4IS4D / Paclitaxel
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16. Giunta JL: Transient lingual papillitis: case reports. J Mass Dent Soc; 2009;58(2):26-7
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  • It describes a condition of the tongue that is relatively common but with few documented cases.
  • [MeSH-major] Glossitis / diagnosis. Taste Buds / pathology

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  • (PMID = 19774866.001).
  • [ISSN] 0025-4800
  • [Journal-full-title] Journal of the Massachusetts Dental Society
  • [ISO-abbreviation] J Mass Dent Soc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Papadimitrakopoulou VA, Brown EN, Liu DD, El-Naggar AK, Jack Lee J, Hong WK, Lee HY: The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis. Cancer Lett; 2006 Jul 28;239(1):136-43
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  • We examined the prognostic role of IGFBP-3 protein expression loss in 34 squamous cell carcinomas (SCC) of the tongue (stages II-IV) and 30 premalignant lesions of the oral cavity and the larynx.
  • Reduced IGFBP-3 expression was found in 11 (32%) of 34 tongue SCC cases, and was associated with significantly shorter disease-specific and disease-free survival (P=0.0002 and <0.0001 by Log-rank test).
  • Therefore, down-regulation of IGFBP-3 is an early event during head and neck carcinogenesis, that bears an adverse prognostic significance in tongue cancer and could serve as both a marker of aggressive disease and target for intervention.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Insulin-Like Growth Factor Binding Protein 3 / metabolism. Laryngeal Neoplasms / metabolism. Mouth Neoplasms / metabolism. Tongue Neoplasms / metabolism
  • [MeSH-minor] Aged. Aged, 80 and over. Down-Regulation. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate

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  • (PMID = 16181731.001).
  • [ISSN] 0304-3835
  • [Journal-full-title] Cancer letters
  • [ISO-abbreviation] Cancer Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Insulin-Like Growth Factor Binding Protein 3
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18. Mehta V, Yu GP, Schantz SP: Population-based analysis of oral and oropharyngeal carcinoma: changing trends of histopathologic differentiation, survival and patient demographics. Laryngoscope; 2010 Nov;120(11):2203-12
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  • To test the hypothesis that decreased histologic differentiation and increased disease-specific survival is related to a decline in smoking rates and an increased percentage of human papillomavirus (HPV)-related tumors.
  • Incidence rates, histologic tumor grade. and 5-year survival rates were analyzed over time.
  • RESULTS: In both OC and OP, well-differentiated (grade I) tumors decreased significantly over time, from 33% to 16% between 1975 and 2006 (P < .001).
  • In contrast, poorly differentiated tumors (grade III) significantly increased from 23% to 34% (P < .001).
  • Over time, 5-year survival rates of less differentiated tumors improved 57%, whereas survival of well-differentiated tumors improved only 15.5%.
  • Tonsil, posterior oropharynx and tongue subsites showed the greatest improvement in survival over time.
  • CONCLUSIONS: Comprehensive population-based analysis of oral cavity and oropharyngeal carcinoma from 1975 to 2006 demonstrated significant trends toward decreased tumor differentiation and increased survival over time.
  • [MeSH-minor] Adult. Age Distribution. Aged. Aged, 80 and over. Biopsy, Needle. Cause of Death. Cohort Studies. Databases, Factual. Disease-Free Survival. Forecasting. Humans. Immunohistochemistry. Incidence. Male. Middle Aged. Neoplasm Staging. Papillomavirus Infections / epidemiology. Prognosis. Retrospective Studies. Risk Assessment. SEER Program. Sex Distribution. Smoking / epidemiology. Survival Analysis. United States

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  • (PMID = 20938956.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Mark Taylor S, Drover C, Maceachern R, Bullock M, Hart R, Psooy B, Trites J: Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer? Oral Oncol; 2010 Jan;46(1):38-41
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  • [Title] Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer?
  • Studies have shown a strong correlation between histological tumor depth and the risk of nodal metastasis.
  • To determine if preoperative ultrasonography is an accurate measure of tumor depth in oral carcinoma.
  • To assess if preoperatively measured tumor depth predicts an increased risk of subclinical metastatic neck disease and thus the need for elective neck dissection.
  • Twenty one consecutive patients with biopsy proven squamous cell carcinoma of the tongue/floor of mouth were analyzed prospectively.
  • Each patient received a preoperative ultrasonography to assess tumor depth which was compared to histological measures.
  • Univariate analysis was used to correlate tumor thickness and T stage with neck metastasis.
  • There was a significant correlation between the preoperative ultrasonography and histological measures of tumor depth (correlation coefficient 0.981, P<0.001).
  • In the group with tumors<5mm in depth, the neck metastatic rate was 0%, as compared with 65% in the group 5mm.
  • Using univariate analysis tumor depth and T stage were significant predictors of cervical metastasis (P=0.0351 and P=0.0300, respectively).
  • Preoperative ultrasonography is an accurate measure of tumor depth in oral carcinoma.
  • Tumor thickness is a significant predictor of nodal metastasis and elective neck dissection should be considered when this thickness is 5mm.
  • [MeSH-minor] Aged. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neck Dissection / methods. Neoplasm Invasiveness. Prognosis. Prospective Studies. Tumor Burden

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  • [CommentIn] Oral Oncol. 2010 Nov;46(11):837 [20729135.001]
  • [CommentIn] Oral Oncol. 2010 Aug;46(8):627; author reply 628 [20371207.001]
  • (PMID = 19932047.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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20. Boon M, Pribitkin E, Spiegel J, Nazarian L, Herbison GJ: Lingual abscess from a grill cleaning brush bristle. Laryngoscope; 2009 Jan;119(1):79-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: This is a report of a patient who presented with severe tongue and ear pain, initially diagnosed with glossopharyngeal neuralgia.
  • Diagnosis may be difficult and as a consequence, when they occur, they may result in airway compromise or sepsis.
  • [MeSH-major] Abscess / radiography. Abscess / surgery. Foreign Bodies / radiography. Foreign Bodies / surgery. Tomography, X-Ray Computed. Tongue Diseases / radiography. Tongue Diseases / surgery
  • [MeSH-minor] Diagnosis, Differential. Household Articles. Humans. Male


21. Tagawa T, Tomita T, Yamaguchi H, Ozawa H, Sakamoto K, Ogawa K, Fujii M: [Clinical study of 28 cases of cervical lymph node metastasis from an unknown primary carcinoma]. Nihon Jibiinkoka Gakkai Kaiho; 2007 Jul;110(7):506-12
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  • In histological diagnosis, open biopsy was conducted in 11 patients and non-open biopsy (FNA or frozen section diagnosis during surgery) in 17.
  • Blind biopsy under general anesthesia was conducted in 10 patients, showing one primary tumor in the nasopharynx.
  • Tonsillectomy for diagnosis was not done.
  • The histopathological diagnosis of cervical lymph node was as follows: squamous cell carcinoma in 21, adenocarcinoma in 3, mucoepidermoid carcinoma in 2, and others in 2.
  • Seven patients were found to have a subsequent primary tumor.
  • Primary tumor sites were as follows: tonsils in 3 and upper gingiva, base of tongue, lung, and nasopharynx in 1 each.
  • FDG-PET was conducted in 7 patients but revealed no primary tumor.
  • We should pay particular attention to the tonsils for detecting primary tumors in patients with cervical metastasis from an unknown primary carcinoma.
  • [MeSH-major] Head and Neck Neoplasms / secondary. Lymph Nodes / pathology. Lymphatic Metastasis / diagnosis. Neoplasms, Unknown Primary / pathology

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  • (PMID = 17695298.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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22. Fehér E, Batbayar B, Vér A, Zelles T: Changes of the different neuropeptide-containing nerve fibers and immunocells in the diabetic rat's alimentary tract. Ann N Y Acad Sci; 2006 Nov;1084:280-95
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  • In this article we have quantified the different neuropeptide-containing nerve fibers and immunocells in the streptozotocin-induced diabetic rat's alimentary tract (tongue, duodenum, colon) using immunohistochemical and immunocytochemical methods.

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  • (PMID = 17151308.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neuropeptide Y; 0 / Neuropeptides; 33507-63-0 / Substance P; EC 1.14.16.2 / Tyrosine 3-Monooxygenase
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23. Peña-Garay M: [The linguistic skills of infants under the age of one year]. Rev Neurol; 2005 Sep 1-15;41(5):291-8
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  • [Transliterated title] Habilidades lingüísticas de los niños menores de un año.
  • In fact, during their early years, children will have to learn the properties that are relevant to their mother tongue, while at the same time ignoring those that are irrelevant.

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  • (PMID = 16138287.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Spain
  • [Number-of-references] 78
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24. Lee CH, Chen SG: Direct percutaneous ethanol instillation for treatment of venous malformation in the face and neck. Br J Plast Surg; 2005 Dec;58(8):1073-8
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  • Under general or local anaesthesia, one-third to one-quarter cavity volume of ethanol was injected percutaneously, directly into the malformation with under fluoroscopy [de Lorimier AA.
  • J Pediatr Surg 1995;30:188-93; Johnson PL, Eckard DA, Brecheisen MA, Girod DA, Tsue TT.
  • Percutaneous ethanol sclerotherapy of venous malformations of the tongue.

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  • (PMID = 16055097.001).
  • [ISSN] 0007-1226
  • [Journal-full-title] British journal of plastic surgery
  • [ISO-abbreviation] Br J Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sclerosing Solutions; 3K9958V90M / Ethanol
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25. Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J: Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13. J Invest Dermatol; 2005 Mar;124(3):536-44
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  • Northern analysis of the new keratins K1b, K6l, K5b, and Kb20 using mRNA of major organs as well as of specific epithelial subtypes shows singular expression of these keratins in skin, hair follicles and, for K5b and Kb20, in tongue, respectively.

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  • [CommentIn] J Invest Dermatol. 2005 Mar;124(3):xv-xvii [15737184.001]
  • (PMID = 15737194.001).
  • [ISSN] 0022-202X
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AJ564103/ AJ564104/ AJ564105/ AJ628418/ AJ628419/ AJ628420/ AJ717743
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / Intermediate Filament Proteins; 0 / KRT20 protein, human; 0 / KRT5 protein, human; 0 / KRT71 protein, human; 0 / KRT77 protein, human; 0 / Keratin-1; 0 / Keratin-20; 0 / Keratin-5; 0 / Keratins, Hair-Specific; 68238-35-7 / Keratins
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26. Nicolaidis K: Aspects of spatio-temporal variability during consonant production by Greek speakers with hearing impairment. Clin Linguist Phon; 2007 Jun;21(6):405-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The technique of electropalatography was used to record tongue-palate contact patterns during consonant production in order to examine differences in articulatory variability among speakers and in V-to-C coarticulatory effects.
  • The study reports durational differences in consonant production between speakers with hearing impairment and normal hearing and investigates the relationship between token-to-token variability in tongue-palate contact patterns and duration.
  • The results indicate a negative relationship between duration and variability, i.e. as segmental duration decreases there is an increase in variability in tongue-palate contact patterns.
  • [MeSH-major] Articulation Disorders / diagnosis. Deafness / diagnosis. Language. Phonetics. Speech Intelligibility. Speech Production Measurement

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  • (PMID = 17516228.001).
  • [ISSN] 0269-9206
  • [Journal-full-title] Clinical linguistics & phonetics
  • [ISO-abbreviation] Clin Linguist Phon
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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27. Brown DJ, Jaffe JE, Henson JK: Advanced laceration management. Emerg Med Clin North Am; 2007 Feb;25(1):83-99
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  • Lacerations of the fingertip, ear, nose, lip, tongue, and eyelid can be complex and require advanced management techniques.

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  • (PMID = 17400074.001).
  • [ISSN] 0733-8627
  • [Journal-full-title] Emergency medicine clinics of North America
  • [ISO-abbreviation] Emerg. Med. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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28. Lai CC, Su CY: Free mucosa graft from the lateral tongue for reconstruction of intraoral buccal/lip mucosal defects after tumor resection. Laryngoscope; 2007 Aug;117(8):1368-72
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  • [Title] Free mucosa graft from the lateral tongue for reconstruction of intraoral buccal/lip mucosal defects after tumor resection.
  • OBJECTIVES: To develop a functional and morphologic reconstruction for intraoral buccal/lip mucosal defects after tumor resection.
  • METHODS: From November 2003 to July 2006, 32 patients underwent free tongue mucosa graft reconstruction after resection of buccal or lip tumors.
  • CONCLUSION: This study demonstrated that free mucosa grafts from the lateral tongue are an excellent alternative for reconstruction of buccal/lip mucosal defects after tumor resection.
  • [MeSH-major] Lip Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Tissue Transplantation / methods. Tongue / transplantation

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  • (PMID = 17592391.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Gibbons BG, Williams KE, Riegel KE: Reducing tube feeds and tongue thrust: combining an oral-motor and behavioral approach to feeding. Am J Occup Ther; 2007 Jul-Aug;61(4):384-91
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  • [Title] Reducing tube feeds and tongue thrust: combining an oral-motor and behavioral approach to feeding.
  • The participant exhibited a tongue thrust, resulting in the expulsion of all foods presented.
  • METHOD: An oral-motor procedure was used to reduce the tongue thrust and allow the food to be swallowed.
  • RESULTS: By the end of treatment, tube feedings were eliminated and tongue thrust was significantly reduced.
  • [MeSH-major] Feeding and Eating Disorders of Childhood / rehabilitation. Occupational Therapy / methods. Tongue Habits / adverse effects

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  • (PMID = 17685170.001).
  • [ISSN] 0272-9490
  • [Journal-full-title] The American journal of occupational therapy : official publication of the American Occupational Therapy Association
  • [ISO-abbreviation] Am J Occup Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Jiang L, Liu X, Chen Z, Jin Y, Heidbreder CE, Kolokythas A, Wang A, Dai Y, Zhou X: MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. Biochem J; 2010 Nov 15;432(1):199-205
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  • [Title] MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells.
  • miR-7 (microRNA-7) has been characterized as a tumour suppressor in several human cancers.
  • However, the mechanism(s) by which miR-7 suppresses tumorigenesis in TSCC (tongue squamous cell carcinoma) is unknown.

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  • (PMID = 20819078.001).
  • [ISSN] 1470-8728
  • [Journal-full-title] The Biochemical journal
  • [ISO-abbreviation] Biochem. J.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R03 CA135992-02; United States / NCI NIH HHS / CA / R03CA135992; United States / NCI NIH HHS / CA / R01 CA139596-03; United States / NIDCR NIH HHS / DE / K22DE014847; United States / NCI NIH HHS / CA / R01CA139596; United States / NCI NIH HHS / CA / R01 CA139596; United States / NCI NIH HHS / CA / R03 CA135992; United States / NIDCR NIH HHS / DE / K22 DE014847-05; United States / NCI NIH HHS / CA / CA139596-03; United States / NIDCR NIH HHS / DE / K22 DE014847
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / MIRN7 microRNA, human; 0 / MicroRNAs; 0 / RNA, Messenger; 67763-96-6 / Insulin-Like Growth Factor I; EC 1.13.12.- / Luciferases; EC 2.7.10.1 / Receptor, IGF Type 1; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt
  • [Other-IDs] NLM/ NIHMS302690; NLM/ PMC3130335
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31. Grigor'ian AS, Grigor'iants LA, Kasparov AS: [Experimental-morphological study of the effects of diode laser scalpel with different irradiation parameters (wave length 0.97 mm) on oral mucosa]. Stomatologiia (Mosk); 2006;85(1):8-13
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  • An experimental-morphologic study of the effects of diode laser scalpel with different irradiation parameters (wave length 0.97 mm) on oral mucosa of 12 rabbits showed that incisions on oral membrane of the tongue, cheek and palate made by diode laser scalpel in different modes of operation (diode laser scalpel LC-0.97-IRE-Polus: in continuous mode /4 W/; frequency modulated mode 2000 x 100 /5 W/; frequency modulated mode 1000 x 50 /6 W/) after 2 hours produced the effect of superficial tissues defects with consequent development in 1-2 days of necrotic changes, oedema and angiomatosis, as well as perifocal inflammatory and productive reactions in the defects walls.
  • In the continuous mode /4 W/ and frequency modulated mode 2000 x 100 /5 W/ to 10th day of the experiment there was epithelization of mucous defects on thr tongue, cheek and palate.
  • [MeSH-minor] Animals. Cheek / surgery. Inflammation. Male. Necrosis. Palate / surgery. Photography. Rabbits. Time Factors. Tongue / surgery

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  • (PMID = 16482020.001).
  • [ISSN] 0039-1735
  • [Journal-full-title] Stomatologii︠a︡
  • [ISO-abbreviation] Stomatologiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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32. Hong KS, Lee JI, Hong SC: Neurological picture. Cerebral proliferative angiopathy associated with haemangioma of the face and tongue. J Neurol Neurosurg Psychiatry; 2010 Jan;81(1):36-7
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  • [Title] Neurological picture. Cerebral proliferative angiopathy associated with haemangioma of the face and tongue.
  • [MeSH-minor] Face. Female. Humans. Magnetic Resonance Angiography. Tongue. Young Adult

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  • (PMID = 20019220.001).
  • [ISSN] 1468-330X
  • [Journal-full-title] Journal of neurology, neurosurgery, and psychiatry
  • [ISO-abbreviation] J. Neurol. Neurosurg. Psychiatry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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33. Lyons MJ, Khalil H, Kotecha BT: Surgical approaches to the tongue base in patients requiring radiofrequency treatment for snoring. Clin Otolaryngol; 2008 Apr;33(2):167-9
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  • [Title] Surgical approaches to the tongue base in patients requiring radiofrequency treatment for snoring.
  • [MeSH-major] Radiosurgery / instrumentation. Snoring / surgery. Tongue / anatomy & histology. Tongue / surgery

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  • (PMID = 18429895.001).
  • [ISSN] 1749-4486
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
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34. Locascio EJ, Mahler SA, Arnold TC: Intestinal angioedema misdiagnosed as recurrent episodes of gastroenteritis. West J Emerg Med; 2010 Sep;11(4):391-4
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  • Emergency physicians (EP) frequently encounter angioedema involving the lips and tongue.

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  • (PMID = 21079716.001).
  • [ISSN] 1936-9018
  • [Journal-full-title] The western journal of emergency medicine
  • [ISO-abbreviation] West J Emerg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2967696
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36. Prinz JF, de Wijk RA, Huntjens LA, Engelen L, Polet IA: Is fat perception a thermal effect? Percept Mot Skills; 2007 Apr;104(2):381-6
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  • The thermal sensitivity of the lips and oral mucosa of the anterior and middle one-third of the tongue were assessed using a Peltier device.
  • Subjects detected 0.5 Hz fluctuations in temperature of 0.08'C on the lower lip, 0.26 degrees C and 1.36 degrees C at the tip and dorsum of the tongue, demonstrating that the lips are sufficiently sensitive to detect small differences in temperature.

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  • (PMID = 17566427.001).
  • [ISSN] 0031-5125
  • [Journal-full-title] Perceptual and motor skills
  • [ISO-abbreviation] Percept Mot Skills
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dietary Fats
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37. Löfqvist A: Interarticulator programming: effects of closure duration on lip and tongue coordination in Japanese. J Acoust Soc Am; 2006 Nov;120(5 Pt 1):2872-83
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  • [Title] Interarticulator programming: effects of closure duration on lip and tongue coordination in Japanese.
  • This paper examines the coordination of lip and tongue movements in sequences of vowel-bilabial consonant-vowel where the duration of the oral closure for the consonant is varied for linguistic purposes.
  • Recordings were made of lip and tongue movements using a magnetometer system.
  • The tongue movement from the first to the second vowel had a longer duration in the long than in the short consonants, and its average speed was slower in the long consonant.
  • The size of the tongue movement path between the vowels did not consistently differ between the long and short consonants.
  • The tongue movement almost always started before the oral closure for the consonant, while the onset of the lip movement towards oral closure mostly started before that of the tongue movement.
  • The offset of the tongue movement occurred after the release of the closure, but there was no clear pattern for the long and short consonants.

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  • (PMID = 17139745.001).
  • [ISSN] 0001-4966
  • [Journal-full-title] The Journal of the Acoustical Society of America
  • [ISO-abbreviation] J. Acoust. Soc. Am.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC000865-10; United States / NIDCD NIH HHS / DC / R01 DC000865; United States / NIDCD NIH HHS / DC / DC-00865; United States / NIDCD NIH HHS / DC / R01 DC000865-10
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS175250; NLM/ PMC2827773
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38. Carinci F, Lo Muzio L, Piattelli A, Rubini C, Chiesa F, Ionna F, Palmieri A, Maiorano E, Pastore A, Laino G, Dolci M, Pezzetti F: Potential markers of tongue tumor progression selected by cDNA microarray. Int J Immunopathol Pharmacol; 2005 Jul-Sep;18(3):513-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Potential markers of tongue tumor progression selected by cDNA microarray.
  • Squamous cell carcinoma (SCC), the most frequent malignant tumor of the oral cavity, generally exhibits a poor prognosis and metastases are the main cause of death.
  • This tumor often arises from pre-malignant lesions.
  • For these reasons, several studies are trying to identify markers useful in the progression of pre-malignant lesions and tumors.
  • To define the genetic expression profile of tongue tumor progression we compared 9 dysplasias (DS), 8 tumors without metastasis (TWM), 11 metastasizing SCCs (MT) of the tongue, and a baseline of 11 normal tissues by using cDNA microarray containing 19.2 K clones.
  • In conclusion, we identified several genes differentially expressed in tumor progression which can potentially help in better classifying pre-malignant lesions and tongue SCCs.
  • [MeSH-major] Biomarkers, Tumor / genetics. Carcinoma, Squamous Cell / genetics. Oligonucleotide Array Sequence Analysis. Tongue / pathology. Tongue Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Algorithms. DNA, Complementary / genetics. DNA, Neoplasm / genetics. Disease Progression. Female. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Precancerous Conditions / classification. Precancerous Conditions / genetics. Precancerous Conditions / metabolism. Software

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  • (PMID = 16164832.001).
  • [ISSN] 0394-6320
  • [Journal-full-title] International journal of immunopathology and pharmacology
  • [ISO-abbreviation] Int J Immunopathol Pharmacol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Complementary; 0 / DNA, Neoplasm
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39. Marie I, Proux A, Levesque H, Bony-Rerolle S, Chenal P: Tongue involvement revealing sarcoidosis. QJM; 2008 Nov;101(11):909-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tongue involvement revealing sarcoidosis.
  • [MeSH-major] Sarcoidosis / pathology. Tongue Diseases / pathology

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  • [CommentIn] QJM. 2009 Feb;102(2):149 [19028747.001]
  • (PMID = 18786978.001).
  • [ISSN] 1460-2393
  • [Journal-full-title] QJM : monthly journal of the Association of Physicians
  • [ISO-abbreviation] QJM
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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40. Kurtulmus H, Cotert HS: Management of obstructive sleep apnea with a mandibular and tongue advancement splint (MTAS) in a completely edentulous patient. A clinical report. J Prosthodont; 2009 Jun;18(4):348-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of obstructive sleep apnea with a mandibular and tongue advancement splint (MTAS) in a completely edentulous patient. A clinical report.
  • This clinical report describes a clinical and laboratory method for producing a functional splint combining an MAS and a tongue-retaining device with an individualized tongue tip housing and discusses the rationale for using such a device.
  • [MeSH-major] Mandibular Advancement / instrumentation. Mouth, Edentulous / complications. Sleep Apnea, Obstructive / therapy. Splints. Tongue / pathology

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  • (PMID = 19210308.001).
  • [ISSN] 1532-849X
  • [Journal-full-title] Journal of prosthodontics : official journal of the American College of Prosthodontists
  • [ISO-abbreviation] J Prosthodont
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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41. Bressmann T, Thind P, Uy C, Bollig C, Gilbert RW, Irish JC: Quantitative three-dimensional ultrasound analysis of tongue protrusion, grooving and symmetry: data from 12 normal speakers and a partial glossectomee. Clin Linguist Phon; 2005 Sep-Nov;19(6-7):573-88
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  • [Title] Quantitative three-dimensional ultrasound analysis of tongue protrusion, grooving and symmetry: data from 12 normal speakers and a partial glossectomee.
  • The functional determinants for a good speech outcome after a partial tongue resection and reconstruction are not well established.
  • The purpose of the present study was to assess the protrusion, grooving and symmetry of the tongue during sustained speech sound production using three-dimensional ultrasound.
  • The glossectomee's postoperative surface plots were characterized by asymmetry and convexity of the tongue surface.
  • The anteriority index illustrated that the glossectomee's ability to protrude her tongue was not affected by the operation.
  • The concavity index captured a decrease in midsagittal grooving in the glossectomee's tongue.
  • The asymmetry index demonstrated height differences in the elevation of the right and left side of the tongue.
  • [MeSH-major] Articulation Disorders / physiopathology. Glossectomy / adverse effects. Movement / physiology. Tongue / physiology. Tongue / ultrasonography
  • [MeSH-minor] Adult. Carcinoma, Squamous Cell / physiopathology. Carcinoma, Squamous Cell / surgery. Case-Control Studies. Female. Humans. Imaging, Three-Dimensional. Male. Middle Aged. Tongue Neoplasms / physiopathology. Tongue Neoplasms / surgery. Ultrasonography / methods

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  • (PMID = 16206485.001).
  • [ISSN] 0269-9206
  • [Journal-full-title] Clinical linguistics & phonetics
  • [ISO-abbreviation] Clin Linguist Phon
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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42. Tizzano M, Merigo F, Sbarbati A: Evidence of solitary chemosensory cells in a large mammal: the diffuse chemosensory system in Bos taurus airways. J Anat; 2006 Sep;209(3):333-7
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  • Using immunocytochemistry for alpha-gustducin, the taste buds of the tongue and arytenoid were visualized.
  • Immunoblotting confirmed the expression of alpha-gustducin in the tongue and in all the airway regions tested.
  • [MeSH-minor] Animals. Female. Immunohistochemistry / methods. Isoenzymes / analysis. Male. Phospholipase C beta. Taste. Tongue / cytology. Transducin / analysis. Type C Phospholipases / analysis

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  • (PMID = 16928202.001).
  • [ISSN] 0021-8782
  • [Journal-full-title] Journal of anatomy
  • [ISO-abbreviation] J. Anat.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Isoenzymes; 147979-21-3 / gustducin; EC 3.1.4.- / Type C Phospholipases; EC 3.1.4.11 / Phospholipase C beta; EC 3.1.4.11 / Plcb2 protein, rat; EC 3.6.1.- / Transducin
  • [Other-IDs] NLM/ PMC2100327
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43. Konitsiotis S, Tsironis C, Kiortsis DN, Evangelou A: Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias. Psychopharmacology (Berl); 2006 Apr;185(3):369-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: All the drugs tested, except dextrorphan, reduced VCMs and tongue protrusions with varying efficacies and side effects profiles.
  • Ro 25-6981 was found significantly more potent than amantadine and ifenprodil in reducing VCMs and tongue protrusions at all doses tested, and at the higher dose, it completely eliminated orofacial dyskinesia (p<0.05).

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  • (PMID = 16518645.001).
  • [ISSN] 0033-3158
  • [Journal-full-title] Psychopharmacology
  • [ISO-abbreviation] Psychopharmacology (Berl.)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antipsychotic Agents; 0 / NR2B NMDA receptor; 0 / Phenols; 0 / Piperidines; 0 / Receptors, N-Methyl-D-Aspartate; 0 / Ro 25-6981; 04B7QNO9WS / Dextrorphan; BF4C9Z1J53 / Amantadine; J6292F8L3D / Haloperidol; R8OE3P6O5S / ifenprodil
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44. Benamer MH, Elmangoush AM: Lingual Osseous Choristoma Case report and review of literature. Libyan J Med; 2007 Mar 01;2(1):46-8
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  • Monserrat in 1913 was the first to report this bony lesion on the dorsum of the tongue and it was labelled as lingual osteoma, the term that normally describes neoplastic pathology.

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  • (PMID = 21503232.001).
  • [ISSN] 1993-2820
  • [Journal-full-title] The Libyan journal of medicine
  • [ISO-abbreviation] Libyan J Med
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3078236
  • [Keywords] NOTNLM ; Lingual osteoma / Osseous choristoma Torus
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45. Simpson AP, Meinhold G: Compensatory articulations in a case of congenital aglossia. Clin Linguist Phon; 2007 Jul;21(7):543-56
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  • This paper examines the articulatory and phonatory strategies used by a German female born without a tongue.
  • [MeSH-major] Social Control, Informal. Speech Disorders / diagnosis. Tongue / abnormalities. Verbal Behavior

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  • (PMID = 17564856.001).
  • [ISSN] 0269-9206
  • [Journal-full-title] Clinical linguistics & phonetics
  • [ISO-abbreviation] Clin Linguist Phon
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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46. Strieth S, Berghaus A: [Piercing complications in the facial area]. MMW Fortschr Med; 2006 Oct 12;148(41):41-3
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  • From the ENT specialist's view, the wearing of piercing jewelry on the outer ear, the tongue, the lips, the nose or the eyebrows is the cause of many and sometimes serious local and also systemic complications.

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  • (PMID = 17190260.001).
  • [ISSN] 1438-3276
  • [Journal-full-title] MMW Fortschritte der Medizin
  • [ISO-abbreviation] MMW Fortschr Med
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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47. Rison RA, Beydoun SR: Teaching Video NeuroImages: tongue myokymia following head and neck radiotherapy for nasopharyngeal carcinoma. Neurology; 2009 Apr 7;72(14):e65
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  • [Title] Teaching Video NeuroImages: tongue myokymia following head and neck radiotherapy for nasopharyngeal carcinoma.
  • [MeSH-major] Myokymia / etiology. Nasopharyngeal Neoplasms / complications. Nasopharyngeal Neoplasms / radiotherapy. Radiotherapy / adverse effects. Tongue Diseases / etiology


48. Murthy J: Salvaging procedure for mutilated cleft palate by simultaneous tongue and pharyngeal flap surgery. Plast Reconstr Surg; 2008 Jul;122(1):29e-30e
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  • [Title] Salvaging procedure for mutilated cleft palate by simultaneous tongue and pharyngeal flap surgery.
  • [MeSH-minor] Adult. Child. Humans. Pharynx / surgery. Reoperation / adverse effects. Tongue / transplantation


49. Ong CK, Chong VF: Imaging of tongue carcinoma. Cancer Imaging; 2006;6:186-93
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  • [Title] Imaging of tongue carcinoma.
  • The tongue enables taste and plays a critical role in formation of food bolus and deglutition.
  • The tongue is also crucial for speech and the earliest sign of tongue paresis is a change in the quality of speech.
  • Given the importance of the tongue, tongue carcinoma should be accurately staged in order to optimise treatment options and preserve organ function.
  • The intent of this review is to familiarize radiologists with the pertinent anatomy of the tongue and the behaviour of tongue carcinoma so as to map malignant infiltration accurately.
  • [MeSH-major] Magnetic Resonance Imaging. Tongue / anatomy & histology. Tongue Neoplasms / diagnosis
  • [MeSH-minor] Humans. Neoplasm Staging. Tomography, X-Ray Computed

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  • [Copyright] (c) International Cancer Imaging Society.
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  • (PMID = 17208674.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 11
  • [Other-IDs] NLM/ PMC1766559
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50. Papaioannou W, Gizani S, Haffajee AD, Quirynen M, Mamai-Homata E, Papagiannoulis L: The microbiota on different oral surfaces in healthy children. Oral Microbiol Immunol; 2009 Jun;24(3):183-9
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  • The profiles of the tongue dorsum and saliva were also similar.
  • [MeSH-minor] Actinomyces / isolation & purification. Age Factors. Aggregatibacter actinomycetemcomitans / isolation & purification. Bacteroides / isolation & purification. Biofilms. Campylobacter rectus / isolation & purification. Child. Child, Preschool. Colony Count, Microbial. DNA, Bacterial / analysis. Dental Plaque / microbiology. Dentition, Mixed. Gingiva / microbiology. Humans. Mouth Mucosa / microbiology. Nucleic Acid Hybridization. Peptostreptococcus / isolation & purification. Porphyromonas gingivalis / isolation & purification. Prevotella melaninogenica / isolation & purification. Saliva / microbiology. Streptococcus / classification. Streptococcus mitis / isolation & purification. Streptococcus oralis / isolation & purification. Tongue / microbiology. Tooth, Deciduous / microbiology. Treponema denticola / isolation & purification

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  • (PMID = 19416446.001).
  • [ISSN] 1399-302X
  • [Journal-full-title] Oral microbiology and immunology
  • [ISO-abbreviation] Oral Microbiol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Bacterial
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51. Quezada S, Turner PL, Alexiev B, Daly B, Cross R: Severe refractory orofacial Crohn's disease: report of a case. Dig Dis Sci; 2009 Oct;54(10):2290-5
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  • Oral involvement is common in patients with Crohn's disease (CD) and can precede intestinal symptoms, making diagnosis difficult.
  • A 41-year-old woman presented with palate and tongue ulcers.
  • Treatment of orofacial CD includes topical or systemic steroids, immunomodulators, and anti-tumor necrosis factor (TNF) therapies.

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  • (PMID = 19082722.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Mikula I: [Craniofacial neuralgias]. Acta Med Croatica; 2008 May;62(2):163-72
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  • Idiopathic trigeminal neuralgia or tic douloureux has been recognized for centuries as an extremely painful disorder most commonly involving the maxillary nerve.
  • Recurrent lancinating, shocklike unilateral pain lasting for seconds to minutes is provoked by non noxious stimulation of the skin at specific sites around the face and less frequently by movement of the tongue.
  • Neurologic and neuroradiologic examination is advised in all cases to rule out diseases such as intracranical tumors, vascular malformations or multiple sclerosis.
  • [MeSH-minor] Glossopharyngeal Nerve Diseases / diagnosis. Glossopharyngeal Nerve Diseases / etiology. Glossopharyngeal Nerve Diseases / therapy. Herpes Zoster Oticus / diagnosis. Herpes Zoster Oticus / etiology. Herpes Zoster Oticus / therapy. Humans. Neuralgia / diagnosis. Neuralgia / etiology. Neuralgia / therapy. Trigeminal Neuralgia / diagnosis. Trigeminal Neuralgia / etiology. Trigeminal Neuralgia / therapy

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  • (PMID = 18710080.001).
  • [ISSN] 1330-0164
  • [Journal-full-title] Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti
  • [ISO-abbreviation] Acta Med Croatica
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Croatia
  • [Number-of-references] 20
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53. van Eijsden M, van der Wal MF, Bonsel GJ: Folic acid knowledge and use in a multi-ethnic pregnancy cohort: the role of language proficiency. BJOG; 2006 Dec;113(12):1446-51
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  • Language proficiency in Dutch was a major determinant of knowledge in all the ethnic groups with a mother tongue other than Dutch [adjusted odds ratios (OR): Western 3.2, non-Western (all countries combined) 7.5], while educational attainment was of secondary importance.

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  • (PMID = 17081188.001).
  • [ISSN] 1470-0328
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 12001-76-2 / Vitamin B Complex; 935E97BOY8 / Folic Acid
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54. Lin V, Jacobson M, Dorion J, Chen J, Nedzelski J: Global assessment of outcomes after varying reinnervation techniques for patients with facial paralysis subsequent to acoustic neuroma excision. Otol Neurotol; 2009 Apr;30(3):408-13
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  • OBJECTIVE: To determine whether there are objective and/or subjective differences in facial function, tongue function and quality of life in patients who have undergone 1) direct facial-to-facial (Primary, 4 patients), 2) direct facial-to-hypoglossal (End-to-End, 7 patients), 3) end-to-side facial-to-hypoglossal nerve anastomoses with sural nerve/greater auricular nerve interposition (End-to-Side with Interposition Graft, 7 patients), and 4) end-to-side facial-to-hypoglossal nerve anastomoses (End-to-Side, 7 patients) after acoustic neuroma excision.
  • Each patient was globally assessed using the Sunnybrook Facial Grading scale (objective), Facial Disability Index (subjective), Oral-Pharyngeal Disability Index (subjective), Tongue Movement/Muscle symmetry (objective), and short-form SF-36 quality-of-life index (subjective).
  • All of these patients had reduced lateral tongue movement as well as ipsilateral tongue atrophy.
  • [MeSH-minor] Adult. Anastomosis, Surgical. Disability Evaluation. Female. Functional Laterality / physiology. Humans. Hypoglossal Nerve / surgery. Male. Middle Aged. Quality of Life. Retrospective Studies. Surveys and Questionnaires. Tongue / innervation. Tongue / physiology. Treatment Outcome


55. Milosavljević N: Interrelationship between learning English language and students' medical education. Srp Arh Celok Lek; 2008 Jul-Aug;136(7-8):441-4
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  • The comparison analysis was done in order to determine the relation of writing and speaking skills in mother tongue and foreign language.
  • As for the English language, the relation of writing and speaking skills was very strong (Pearson C = 0.641, p < 0.01), while in the mother tongue it was slightly lower (Pearson C = 0.44, p < 0.01).
  • The writing and speaking skills in the mother tongue and in English were significantly positively associated with students' satisfaction with their social and economic status, while satisfaction with achievements at the Faculty was associated only with the ability of verbal expression in the mother tongue.

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  • (PMID = 18959184.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Serbia
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56. Hassan S, Sidek DS, Shah Jihan WD, Phutane G, Mutum SS: Massive lingual teratoma in a neonate. Singapore Med J; 2007 Aug;48(8):e212-4
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  • Teratoma of the tongue is a rare entity.
  • [MeSH-major] Teratoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17657368.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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57. Halli R, Kini R, Bither S: Ductal adenocarcinoma of ventral surface of the tongue: an unusual presentation. Indian J Cancer; 2008 Oct-Dec;45(4):176-8
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  • [Title] Ductal adenocarcinoma of ventral surface of the tongue: an unusual presentation.
  • There are very few cases reported of adenocarcinoma of the tongue.
  • We report an unusual case of a 60-year-old female having a large, pedunculated ductal adenocarcinoma that had arisen from ventral surface of the tongue.
  • [MeSH-major] Carcinoma, Ductal / pathology. Tongue Neoplasms / pathology

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  • [CommentIn] Indian J Cancer. 2009 Jul-Sep;46(3):254-5 [19574689.001]
  • (PMID = 19112208.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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58. Yu Y, Zhong Q, Li C, Jiang L, Yan F, Wang Z, Zhang Q: Isolation and characterization of Toll-like receptor 9 in half-smooth tongue sole Cynoglossus semilaevis. Fish Shellfish Immunol; 2009 Mar;26(3):492-9
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  • [Title] Isolation and characterization of Toll-like receptor 9 in half-smooth tongue sole Cynoglossus semilaevis.
  • In the current study, the TLR9 gene was isolated from one of flatfish species, half-smooth tongue sole (Cynoglossus semilaevis).

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  • (PMID = 19340952.001).
  • [ISSN] 1095-9947
  • [Journal-full-title] Fish & shellfish immunology
  • [ISO-abbreviation] Fish Shellfish Immunol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ FJ418072
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Toll-Like Receptor 9
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59. Yano K, Hosokawa K, Kubo T: Combined tongue flap and V-Y advancement flap for lower lip defects. Br J Plast Surg; 2005 Mar;58(2):258-62
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  • [Title] Combined tongue flap and V-Y advancement flap for lower lip defects.
  • A combined tongue flap and V-Y advanced flap were used for reconstruction of the lower lip after radical excision of squamous cell carcinoma.
  • The vermilion is reconstructed with a tongue flap, with almost no disturbance in the patients' speaking or eating and satisfactory cosmetic results.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Lip / surgery. Lip Neoplasms / surgery. Surgical Flaps. Tongue / surgery

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  • (PMID = 15710124.001).
  • [ISSN] 0007-1226
  • [Journal-full-title] British journal of plastic surgery
  • [ISO-abbreviation] Br J Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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60. Yunusova Y, Weismer G, Westbury JR, Lindstrom MJ: Articulatory movements during vowels in speakers with dysarthria and healthy controls. J Speech Lang Hear Res; 2008 Jun;51(3):596-611
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  • PURPOSE: This study compared movement characteristics of markers attached to the jaw, lower lip, tongue blade, and dorsum during production of selected English vowels by normal speakers and speakers with dysarthria due to amyotrophic lateral sclerosis (ALS) or Parkinson disease (PD).
  • The severity of dysarthria varied across individuals and between the 2 disorder groups.
  • Tongue movements in PD and ALS were more consistently different from healthy controls than jaw and lower lip movements.
  • These factors need to be carefully considered when describing the nature of speech disorder and developing empirically based evaluation and treatment strategies for dysarthria.

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  • (PMID = 18506038.001).
  • [ISSN] 1092-4388
  • [Journal-full-title] Journal of speech, language, and hearing research : JSLHR
  • [ISO-abbreviation] J. Speech Lang. Hear. Res.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC003723
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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61. Quitadamo C, Fabbretti E, Lamanauskas N, Nistri A: Activation and desensitization of neuronal nicotinic receptors modulate glutamatergic transmission on neonatal rat hypoglossal motoneurons. Eur J Neurosci; 2005 Dec;22(11):2723-34
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  • In the neonate the muscles of the tongue, which are exclusively innervated by the XII cranial nerves originating from the brainstem nucleus hypoglossus, must contract rhythmically in coincidence with breathing, suckling and swallowing.
  • These results highlight the role of tonic nAChR activity in shaping excitatory inputs to hypoglossal motoneurons, and suggest that nAChR desensitization by ambient nicotine could contribute to disorders of tongue muscle movements.

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  • (PMID = 16324106.001).
  • [ISSN] 0953-816X
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Glutamates; 0 / Nicotinic Agonists; 0 / Nicotinic Antagonists; 0 / Receptors, Nicotinic; 6M3C89ZY6R / Nicotine
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62. Nemes JA, Redl P, Boda R, Kiss C, Márton IJ: Oral cancer report from Northeastern Hungary. Pathol Oncol Res; 2008 Mar;14(1):85-92
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  • The most common sites of OSCC were the floor of the mouth (27.7%), the lip (26.9%) and the tongue (22.7%).
  • The majority of the patients was diagnosed with early stage (I-II) lesions and moderately differentiated tumors.
  • There was a significant correlation between survival and tumor size, lymph node involvement and clinical stage.
  • At the time of diagnosis 65.5% of the patients were smokers.
  • Drinking habit significantly correlated with younger age, male gender and tumor site i.e. gingiva, retromolar region, tongue.

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  • (PMID = 18351444.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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63. Wen HS, Wang JM, Zhou H, Xia R, Qiu HY, Gao L, Hu XX: [Migration and distribution of allogeneic T lymphocytes in organs of graft-versus-host disease mouse model]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2006 Oct;14(5):919-23
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  • The results indicated that GVHD clinical manifestation and pathological changes of organs appeared on day 8 post transplantation. eGFP-positive donor T cells in recipient organs were observed by inverted fluorescence microscope in frozen section, or by stereo-fluorescence microscopy in living organs, such as liver, spleen, skin, lungs, bowels, and tongue.
  • In this GVHD model, donor T cells proliferate and infiltrate in liver, skin, bowels, as well as lungs and tongue.

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  • (PMID = 17096889.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 147336-22-9 / Green Fluorescent Proteins
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64. Green BG, Alvarez-Reeves M, George P, Akirav C: Chemesthesis and taste: evidence of independent processing of sensation intensity. Physiol Behav; 2005 Nov 15;86(4):526-37
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  • In experiment 1, subjects identified as 'thermal tasters' (TTs) or 'thermal non-tasters' (TnTs) used the general Labeled Magnitude Scale to rate the intensity of sensations produced on the tongue tip by capsaicin, menthol, sucrose, NaCl, citric acid, and QSO4.
  • In experiment 2, testing with capsaicin on both the front and back of the tongue confirmed there was no difference in ratings of burning/stinging/pricking when subjects were grouped according to the ability to perceive thermal taste.

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  • (PMID = 16199067.001).
  • [ISSN] 0031-9384
  • [Journal-full-title] Physiology & behavior
  • [ISO-abbreviation] Physiol. Behav.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC05002
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 1490-04-6 / Menthol; 451W47IQ8X / Sodium Chloride; 57-50-1 / Sucrose; S07O44R1ZM / Capsaicin
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65. Noguchi T, Jinbu Y, Itoh H, Matsumoto K, Sakai O, Kusama M: Epignathus combined with cleft palate, lobulated tongue, and lingual hamartoma: report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Apr;101(4):481-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epignathus combined with cleft palate, lobulated tongue, and lingual hamartoma: report of a case.
  • A case of epignathus combined with cleft palate, lobulated tongue, and lingual hamartoma is reported.
  • A newborn female presented with a large skin-covered mass arising from the palate, cleft palate, and lobulated tongue with a soybean-sized lingual lesion.
  • The mass of the tongue dorsum was diagnosed as hamartoma.
  • [MeSH-major] Cleft Palate / complications. Hamartoma / complications. Palatal Neoplasms / complications. Teratoma / complications. Tongue Neoplasms / complications
  • [MeSH-minor] Abnormalities, Multiple. Female. Humans. Infant, Newborn. Palate, Hard / abnormalities. Tongue / abnormalities

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  • (PMID = 16545713.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Tamam L, Annagur BB: Black hairy tongue associated with olanzapine treatment: a case report. Mt Sinai J Med; 2006 Oct;73(6):891-4
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  • [Title] Black hairy tongue associated with olanzapine treatment: a case report.
  • Olanzapine is an atypical antipsychotic drug approved for acute and long-term treatment of bipolar disorder.
  • Although there are several cases in which the tongue was affected in conjunction with stomatitis or pharyngitis, we could not find a case report indicating a direct relationship between olanzapine use and a tongue lesion.
  • We present here the case of a patient with bipolar disorder, who developed recurrent black hairy tongue on two different occasions following the addition of olanzapine to lithium treatment.
  • In the present case, xerostomia (dry mouth), which is an adverse reaction of both olanzapine and lithium, may have played a role in the development of black hairy tongue.
  • All agents with a possible side effect of xerostomia may predispose patients to black hairy tongue, especially when they are administered in combination.
  • [MeSH-major] Antipsychotic Agents / adverse effects. Serotonin Uptake Inhibitors / adverse effects. Tongue, Hairy / chemically induced
  • [MeSH-minor] Adult. Benzodiazepines / adverse effects. Bipolar Disorder / drug therapy. Female. Humans


67. Vaglio A, Milunsky A, Quadrelli A, Huang XL, Maher T, Mechoso B, Martínez S, Pagano S, Bellini S, Costabel M, Quadrelli R: Clinical, cytogenetic, and molecular characterization of a girl with some clinical features of Down syndrome resulting from a pure partial trisomy 21q22.11-qter due to a de novo intrachromosomal duplication. Genet Test Mol Biomarkers; 2010 Feb;14(1):57-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical, cytogenetic, and molecular characterization of a girl with some clinical features of Down syndrome resulting from a pure partial trisomy 21q22.11-qter due to a de novo intrachromosomal duplication.
  • We report a girl with a de novo pure partial trisomy 21 with some clinical features of Down syndrome.
  • Her mouth was wide with downturned corners, prominent lower lip, narrow and furrowed tongue, and short palate.
  • Subtelomeric fluorescent in situ hybridization (FISH) analyses, LSI 13 (retinoblastoma 1 [RB1])/LSI 21(21q22.13-q22.2), and whole chromosome painting probes specific for chromosome 21 showed trisomy for the segment 21q22.13-21q22.2 due to a de novo intrachromosomal duplication.
  • The karyotype was provisionally defined as 46,XX,add(21)(p12).ish der (21)t(21;21)(p12;q22.11)(WCP21q+,PCP21q++,D215259/D21S341/D21S342++)dn.


68. Kovács AF, Eberlein K, Hülsmann T: Organ preservation treatment using TPF-a pilot study in patients with advanced primary and recurrent cancer of the oral cavity and the maxillary sinus. Oral Maxillofac Surg; 2009 Jun;13(2):87-93
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  • Reasons for incomplete treatment were tumor progression, edema, seizure, bad general condition, sepsis, pneumonia (each once).
  • A target for organ preservation could be the maxillary sinus; due to tumor regression in advanced oral tongue cancer, consecutively, a reduced function has to be encountered.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Squamous Cell / drug therapy. Maxillary Sinus Neoplasms / drug therapy. Mouth Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy
  • [MeSH-minor] Aged. Antimetabolites, Antineoplastic / administration & dosage. Antimetabolites, Antineoplastic / adverse effects. Antineoplastic Agents / administration & dosage. Antineoplastic Agents / adverse effects. Cisplatin / administration & dosage. Cisplatin / adverse effects. Cisplatin / therapeutic use. Disease Progression. Feasibility Studies. Female. Fluorouracil / administration & dosage. Fluorouracil / adverse effects. Fluorouracil / therapeutic use. Follow-Up Studies. Humans. Leukopenia / chemically induced. Male. Middle Aged. Neoplasm Staging. Neutropenia / chemically induced. Opportunistic Infections / etiology. Pilot Projects. Prospective Studies. Radiotherapy, Adjuvant. Remission Induction. Stomatitis / chemically induced. Survival Rate. Taxoids / administration & dosage. Taxoids / adverse effects. Taxoids / therapeutic use

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  • (PMID = 19430823.001).
  • [ISSN] 1865-1550
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Taxoids; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil; TPF protocol
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69. Lähteenmäki PM, Sankila R, Pukkala E, Kyyrönen P, Harila-Saari A: Scholastic achievement of children with lymphoma or Wilms tumor at the end of comprehensive education--a nationwide, register-based study. Int J Cancer; 2008 Nov 15;123(10):2401-5
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  • [Title] Scholastic achievement of children with lymphoma or Wilms tumor at the end of comprehensive education--a nationwide, register-based study.
  • School report grades after childhood lymphomas and Wilms tumor have not been previously reported.
  • All Finnish patients with Wilms tumor (N = 74), Hodgkin lymphoma (HL) (N = 99) and non-Hodgkin lymphoma (NHL) (N = 94) who were born in 1974-1986 and had achieved the age of 16 years were identified from the Finnish cancer registry.
  • The overall average and grades for mother tongue, first foreign language, mathematics and physical education were compared between the patients and their controls.
  • Irradiation or age at diagnosis did not explain this difference in NHL patients.
  • In mother tongue, girls with irradiation had greatest difference (-0.66, 95% CI -0.99, -0.34) to their controls.
  • Patients with HL and Wilms tumor performed similarly or even better than their controls in all academic subjects.
  • Grades for physical education were impaired in Wilms tumor patients (-0.20; 95% CI -0.33, -0.06).
  • The patients with HL and Wilms tumor, who had not received any central nervous system directed therapy, achieved equally good grades as their controls in all the academic subjects.
  • [MeSH-major] Educational Status. Hodgkin Disease / psychology. Lymphoma, Non-Hodgkin / psychology. Registries. Wilms Tumor / psychology

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18651572.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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70. Neo M, Asato R, Honda K, Kataoka K, Fujibayashi S, Nakamura T: Transmaxillary and transmandibular approach to a C1 chordoma. Spine (Phila Pa 1976); 2007 Apr 1;32(7):E236-9
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  • SUMMARY OF BACKGROUND DATA: Although aggressive surgical resection has been recommended for the treatment of chordomas, wide exposure of the tumors in the upper cervical region is a challenge.
  • Ten days after the fusion, the tumor was resected using a mandible and tongue midsplitting approach combined with a Le Fort I (transmaxillary) osteotomy, which allowed us to expose the entire tumor.
  • The tumor was hard and immovable because of ossification.
  • The main part of the tumor was resected from the anterior arch of C1, and then the C1 anterior arch was resected en bloc.
  • This enabled us to resect totally the tumor into 2 pieces without major complications or sequelae.
  • This approach is useful for the resection of large tumors located in the median upper cervical spine.
  • [MeSH-minor] Adult. Humans. Male. Osteotomy / methods. Spinal Fusion / methods. Tongue / surgery. Treatment Outcome


71. Rajendran R, Rani V, Shaikh S: Pentoxifylline therapy: a new adjunct in the treatment of oral submucous fibrosis. Indian J Dent Res; 2006 Oct-Dec;17(4):190-8
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  • Significant comparisons with regard to improvement were recorded as objective criteria of mouth opening (t=11.285, p= 0.000), tongue protrusion (t= 3.898, p = 0.002), and relief from perioral fibrotic bands (p = 0.0001554).
  • [MeSH-minor] Adult. Case-Control Studies. Deglutition Disorders / physiopathology. Female. Follow-Up Studies. Humans. Male. Mandible / physiopathology. Mouth Mucosa / drug effects. Movement. Pilot Projects. Prospective Studies. Salivation / drug effects. Tinnitus / physiopathology. Tongue / drug effects. Treatment Outcome. Voice Disorders / physiopathology

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  • (PMID = 17217216.001).
  • [ISSN] 0970-9290
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Vasodilator Agents; SD6QCT3TSU / Pentoxifylline
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72. De Zinis LO, Bolzoni A, Piazza C, Nicolai P: Prevalence and localization of nodal metastases in squamous cell carcinoma of the oral cavity: role and extension of neck dissection. Eur Arch Otorhinolaryngol; 2006 Dec;263(12):1131-5
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  • Moreover, ND should always encompass level IV due to the possibility of skip metastases, particularly in tumors involving the oral tongue.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neck Dissection. Neoplasm Invasiveness. Neoplasm Staging. Prevalence. Retrospective Studies

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  • (PMID = 17004089.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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73. Steenland HW, Liu H, Sood S, Liu X, Horner RL: Respiratory activation of the genioglossus muscle involves both non-NMDA and NMDA glutamate receptors at the hypoglossal motor nucleus in vivo. Neuroscience; 2006;138(4):1407-24
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  • Brainstem respiratory neurons innervate the hypoglossal motor nucleus which in turn transmits this respiratory drive signal to the genioglossus muscle of the tongue.
  • [MeSH-major] Hypoglossal Nerve / physiology. Medulla Oblongata / physiology. Motor Neurons / physiology. Receptors, N-Methyl-D-Aspartate / metabolism. Respiratory Physiological Phenomena / drug effects. Tongue / innervation

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  • (PMID = 16476523.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Excitatory Amino Acid Antagonists; 0 / Receptors, N-Methyl-D-Aspartate; 3KX376GY7L / Glutamic Acid; 6OTE87SCCW / 6-Cyano-7-nitroquinoxaline-2,3-dione; 76726-92-6 / 2-Amino-5-phosphonovalerate
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74. Chung JC, Ng RW: A huge tongue lipoma. Otolaryngol Head Neck Surg; 2007 Nov;137(5):830-1
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  • [Title] A huge tongue lipoma.
  • [MeSH-major] Lipoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17967655.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Hiraba H, Sato T, Nakayama E, Yamaoka M, Inoue M, Sato M, Iida T, Wada S, Ueda K: Changes in localized arrangement into the hypoglossal nucleus after the neurectomy of unilateral hypoglossal nerve (medial branch) in cats. Somatosens Mot Res; 2010;27(3):93-9
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  • After nerve cutting, the cats' tongue deviated toward the cut side when they licked food, and bilateral activities of EMGs in the genioglossus muscles became stable in about 1 month.
  • [MeSH-major] Hypoglossal Nerve Injuries. Medulla Oblongata / physiology. Motor Neurons / physiology. Tongue / innervation

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  • (PMID = 20653500.001).
  • [ISSN] 1369-1651
  • [Journal-full-title] Somatosensory & motor research
  • [ISO-abbreviation] Somatosens Mot Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Fluorescent Dyes
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76. Dahl K, Karlsson M, Marits P, Hoffstedt A, Winqvist O, Thörn M: Metinel node--the first lymph node draining a metastasis--contains tumor-reactive lymphocytes. Ann Surg Oncol; 2008 May;15(5):1454-63
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  • [Title] Metinel node--the first lymph node draining a metastasis--contains tumor-reactive lymphocytes.
  • BACKGROUND: We previously identified tumor-reactive lymphocytes in the first lymph nodes that drain the primary tumor.
  • In this study, we performed lymphatic mapping to investigate the possibility of finding the first lymph nodes that drain metastases, and of learning whether these lymph nodes contained tumor-reactive lymphocytes suitable for adoptive immunotherapy.
  • The primary tumor site was colorectal cancer in seven patients, malignant melanoma in four, ovarian cancer and breast cancer in two, and one each with pancreatic cancer, cholangiocarcinoma, leiomyosarcoma, and squamous cellular cancer of the tongue.
  • Lymphocytes from the metinel nodes proliferated, showed clonal expansion, and produced interferon gamma (via in vitro expansions on stimulation with tumor homogenate) and interleukins, all of which demonstrate the characteristics of tumor-reactive lymphocytes.
  • Eight of the nineteen patients received immunotherapy on the basis of tumor-reactive T cells derived from the metinel nodes.
  • [MeSH-major] Liver Neoplasms / secondary. Lymph Nodes / pathology. Lymphocytes, Tumor-Infiltrating / pathology
  • [MeSH-minor] Adult. Aged. Cells, Cultured. Female. Humans. Immunoenzyme Techniques. Immunotherapy. Interferon-gamma / secretion. Lymphatic Metastasis / diagnosis. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / prevention & control. Preoperative Care. Prognosis. Radiopharmaceuticals. Rosaniline Dyes. Technetium Tc 99m Sulfur Colloid

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  • (PMID = 18299934.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Rosaniline Dyes; 129-17-9 / patent blue violet; 556Q0P6PB1 / Technetium Tc 99m Sulfur Colloid; 82115-62-6 / Interferon-gamma
  • [Other-IDs] NLM/ PMC2277445
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77. Preyde M: Mothers of very preterm infants:perspectives on their situation and a culturally sensitive intervention. Soc Work Health Care; 2007;44(4):65-83
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  • The intervention was delivered in a metropolitan city in Canada with a considerably diverse population, for example, 41% spoke a mother tongue other than one of the two official languages (English and French) and 37% were a visible minority.

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  • (PMID = 17804342.001).
  • [ISSN] 0098-1389
  • [Journal-full-title] Social work in health care
  • [ISO-abbreviation] Soc Work Health Care
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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78. Frank-Raue K, Rondot S, Schulze E, Raue F: Change in the spectrum of RET mutations diagnosed between 1994 and 2006. Clin Lab; 2007;53(5-6):273-82
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  • Medullary thyroid carcinoma (MTC) is a rare calcitonin producing tumor.
  • Hereditary MTC is divided into three clinical subtypes: multiple endocrine neoplasia (MEN) type 2A is characterized by MTC, pheochromocytoma and primary hyperparathyroidism.
  • MEN 2B is characterized by aggressive MTC, pheochromocytoma, marfanoid habitus and the presence of distinctive mucosal neuromas on the tongue, lips and subconjunctival areas as well as ganglioneuromatosis of the gastrointestinal tract.
  • [MeSH-major] Carcinoma, Medullary / genetics. Multiple Endocrine Neoplasia Type 2a / genetics. Multiple Endocrine Neoplasia Type 2b / genetics. Mutation / genetics. Proto-Oncogene Proteins c-ret / genetics. Thyroid Neoplasms / genetics

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  • (PMID = 17605401.001).
  • [ISSN] 1433-6510
  • [Journal-full-title] Clinical laboratory
  • [ISO-abbreviation] Clin. Lab.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA Primers; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human
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79. Saif MW: Hypersensitivity reactions associated with oxaliplatin. Expert Opin Drug Saf; 2006 Sep;5(5):687-94
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  • HSR to oxaliplatin may manifest as facial flushing, rash/hives, tachycardia, dyspnoea, erythema, pruritus, fever, tongue swelling, headache, chills, weakness, vomiting, burning sensations, dizziness and oedema.

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  • (PMID = 16907658.001).
  • [ISSN] 1744-764X
  • [Journal-full-title] Expert opinion on drug safety
  • [ISO-abbreviation] Expert Opin Drug Saf
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin
  • [Number-of-references] 33
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80. Martinez Calixto LE, Suresh L, Matsumura E, Aguirre A, Radfar L: Oral pityriasis rubra pilaris. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 May;101(5):604-7
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  • A case of a 68-year-old man with pityriasis rubra pilaris with involvement of tongue and palate is presented.
  • [MeSH-minor] Aged. Anti-Inflammatory Agents / administration & dosage. Dexamethasone / administration & dosage. Humans. Male. Mouthwashes / administration & dosage. Palate, Hard / pathology. Retinoids / therapeutic use. Tongue / pathology. Vitamins / therapeutic use

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  • (PMID = 16632271.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Mouthwashes; 0 / Retinoids; 0 / Vitamins; 7S5I7G3JQL / Dexamethasone
  • [Number-of-references] 28
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81. Totan C, Dincă O, Negureanu M, Vlădan C, Bucur A: [Distant metastases of malignant tumors of head and neck]. Chirurgia (Bucur); 2010 Sep-Oct;105(5):673-6
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  • [Title] [Distant metastases of malignant tumors of head and neck].
  • [Transliterated title] Metastazele la distanţă ale tumorilor maligne ale capului si gâtului.
  • The overall incidence of distant metastases was 27.84%, varying from 10.52% for buccal mucosa to 63.63% for tongue and floor of the mouth (p < 0.05).
  • [MeSH-minor] Humans. Medical Records. Mouth Neoplasms / secondary. Neck Dissection. Neoplasm Metastasis. Neoplasm Staging. Retrospective Studies. Tongue Neoplasms / secondary. Treatment Outcome

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  • (PMID = 21141093.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
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82. Singer C, Papapetropoulos S: A comparison of jaw-closing and jaw-opening idiopathic oromandibular dystonia. Parkinsonism Relat Disord; 2006 Mar;12(2):115-8
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  • Male gender, orobuccolingual dyskinesias (facial grimacing, lip biting, tongue dyskinesias, platysma contractions and bruxism) and better response to botulinum toxin injections were more frequent in C-OMD but remained a trend.

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  • (PMID = 16271495.001).
  • [ISSN] 1353-8020
  • [Journal-full-title] Parkinsonism & related disorders
  • [ISO-abbreviation] Parkinsonism Relat. Disord.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neuromuscular Agents; EC 3.4.24.69 / Botulinum Toxins, Type A
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83. Sidhu MK, Perkins JA, Shaw DW, Bittles MA, Andrews RT: Ultrasound-guided endovenous diode laser in the treatment of congenital venous malformations: preliminary experience. J Vasc Interv Radiol; 2005 Jun;16(6):879-84
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  • One patient had a self-limited mucosal tongue base ulcer.

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  • (PMID = 15947054.001).
  • [ISSN] 1051-0443
  • [Journal-full-title] Journal of vascular and interventional radiology : JVIR
  • [ISO-abbreviation] J Vasc Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Xu H, Delling M, Jun JC, Clapham DE: Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci; 2006 May;9(5):628-35
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  • When applied to the tongue, these flavors elicit a warm sensation.
  • The transient receptor potential channel (TRPV3) is a warm-sensitive Ca2+-permeable cation channel highly expressed in the skin, tongue and nose.
  • Tongue and skin epithelial cells respond to carvacrol and eugenol with an increase in intracellular Ca2+ levels.
  • [MeSH-minor] Animals. Animals, Newborn. Cells, Cultured. Dose-Response Relationship, Drug. Enzyme-Linked Immunosorbent Assay / methods. Gene Expression / drug effects. Green Fluorescent Proteins / metabolism. Humans. In Situ Hybridization / methods. Indoles. Interleukin-1 / metabolism. Membrane Potentials / drug effects. Membrane Potentials / physiology. Membrane Potentials / radiation effects. Mice. Nasal Mucosa / cytology. Patch-Clamp Techniques / methods. Rats. Rats, Sprague-Dawley. Tongue / cytology. Transfection / methods


85. ter Horst M, Tjiang GC, Luitwieler RL, van Velzen C, Stolker RJ, de Quelerij M: [Antidote against local anaesthetic intoxication: new use of lipid emulsion for intravenous administration]. Ned Tijdschr Geneeskd; 2010;154:A1302
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  • [Transliterated title] Tegengif voor intoxicatie door lokale anesthetica: nieuwe toepassing van vetemulsie voor intraveneuze toediening.
  • The symptoms include numbness of the tongue, dizziness, tinnitus, visual disturbances, muscle spasms, convulsions, coma, and respiratory and cardiac arrest.

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  • (PMID = 20977791.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anesthetics, Local; 0 / Fat Emulsions, Intravenous
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86. Kremer MJ, Blair T: Ludwig angina: forewarned is forearmed. AANA J; 2006 Dec;74(6):445-51
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  • Accurate diagnosis, airway control, antibiotic therapy, and, occasionally, surgical management are essential for patient safety.
  • Ludwig angina is caused by a rapidly expanding cellulitis of the floor of the mouth and is characterized by hardened induration of the floor and suprahyoid region bilaterally with an elevation of the tongue potentially obstructing the airway.

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  • (PMID = 17236391.001).
  • [ISSN] 0094-6354
  • [Journal-full-title] AANA journal
  • [ISO-abbreviation] AANA J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
  • [Number-of-references] 17
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87. Liu ZJ, Yamamura B, Shcherbatyy V, Green JR: Regional volumetric change of the tongue during mastication in pigs. J Oral Rehabil; 2008 Aug;35(8):604-12
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  • [Title] Regional volumetric change of the tongue during mastication in pigs.
  • Structure and movement of the tongue have been studied extensively, but little study has been carried on its 3D deformation and ensuing volumetric changes during various functions.
  • The purpose of this study is to investigate the volumetric changes of a regional section of the tongue during feeding.
  • During natural mastication and water drinking, the width, length, thickness and volumetric changes were measured using six implanted ultrasonic crystals, which circumscribed a wedge-shaped volume in the region of the tongue body.
  • These results revealed that regional volumetric change of the tongue occurs during feeding and chewing requires larger volumetric changes than do ingestion and drinking.
  • The results further suggested that the regional volumetric expansion may play the determinant role in functional load production on its surrounding tissues, and may also imply that neuromuscular control of the tongue is region-specific, a notion incompatible with traditional scheme of categorizing muscle function in the tongue.

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  • (PMID = 18482351.001).
  • [ISSN] 1365-2842
  • [Journal-full-title] Journal of oral rehabilitation
  • [ISO-abbreviation] J Oral Rehabil
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / R01 DE015659-03; United States / NIDCR NIH HHS / DE / R01 DE015659-01A1; United States / NIDCR NIH HHS / DE / T32DE007132; United States / NIDCR NIH HHS / DE / R01DE15659; United States / NIDCR NIH HHS / DE / T32 DE007132; United States / NIDCR NIH HHS / DE / R01 DE015659-02; United States / NIDCR NIH HHS / DE / R01 DE015659
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS34540; NLM/ PMC2574535
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88. Di Marco P, Della Rocca G, Iannuccelli F, Pompei L, Reale C, Pietropaoli P: Knowledge of residual curarization: an Italian survey. Acta Anaesthesiol Scand; 2010 Mar;54(3):307-12
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  • The main clinical tests cited for the evaluation of residual paralysis were keeping the head lifted up for 5 s, protruding the tongue and opening the eyes.
  • [MeSH-minor] Adult. Anesthesia Recovery Period. Anesthesiology. Electric Stimulation. Female. Health Care Surveys. Humans. Italy. Male. Monitoring, Physiologic. Postoperative Complications / diagnosis. Postoperative Complications / epidemiology. Surveys and Questionnaires

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  • (PMID = 19839947.001).
  • [ISSN] 1399-6576
  • [Journal-full-title] Acta anaesthesiologica Scandinavica
  • [ISO-abbreviation] Acta Anaesthesiol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neuromuscular Nondepolarizing Agents
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89. Marioni G, Savastano M, Mattiello L, Koussis H, Carpenè S, Marino F, Staffieri A: Tongue base metastasis from neuroendocrine endometrial small cell carcinoma. Am J Otolaryngol; 2007 Jul-Aug;28(4):284-7
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  • [Title] Tongue base metastasis from neuroendocrine endometrial small cell carcinoma.
  • Although the most common presenting sign of ESCC is definitely a peri- or postmenopausal vaginal bleeding, we report for the first time the occurrence of tongue base bleeding as first manifestation of disseminated neuroendocrine ESCC.
  • From a clinical viewpoint, tongue metastasis from primary endometrial carcinoma is a manifestation of widespread disease.
  • Albeit, our patient underwent complete hysterectomy and postoperative chemotherapy, she died of disseminated disease 3 months after ESCC diagnosis.
  • [MeSH-major] Carcinoma, Small Cell / secondary. Endometrial Neoplasms / pathology. Tongue Neoplasms / secondary

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  • (PMID = 17606050.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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90. Sabolek M, Bayerle M: [Rabbit syndrome due to olanzapine]. Psychiatr Prax; 2005 May;32(4):202-4
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  • It is characterized by involuntary, rhythmic dyskinesias of mouth and lips excluding the tongue, and is most common under typical neuroleptics.
  • We report a 74 year-old patient suffering from a bipolar affective disorder, who developed a rabbit syndrome following the intake of 20 mg/d olanzapine.
  • [MeSH-major] Antipsychotic Agents / adverse effects. Bipolar Disorder / drug therapy. Dyskinesia, Drug-Induced / etiology

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  • (PMID = 15852213.001).
  • [ISSN] 0303-4259
  • [Journal-full-title] Psychiatrische Praxis
  • [ISO-abbreviation] Psychiatr Prax
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antipsychotic Agents; 12794-10-4 / Benzodiazepines; 132539-06-1 / olanzapine
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91. Karahan S, Kul BC: Ankyloglossia in dogs: a morphological and immunohistochemical study. Anat Histol Embryol; 2009 Apr;38(2):118-21
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  • Ankyloglossia is a congenital anomaly of the tongue that is usually characterized by a short and thick lingual frenulum.
  • Grossly, the lingual frenulum was observed as it extended up to the tip or near the tip of the tongue.
  • The tip of the tongue was often notched and appeared in 'W' shape.
  • [MeSH-major] Dog Diseases / pathology. Tongue / abnormalities. Tongue Diseases / veterinary

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  • (PMID = 19007356.001).
  • [ISSN] 1439-0264
  • [Journal-full-title] Anatomia, histologia, embryologia
  • [ISO-abbreviation] Anat Histol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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92. Mehndiratta MM: Trigeminal motor neuropathy with tongue fasciculations in a patient with chronic inflammatory demyelinating polyradiculoneuropathy. J Clin Neurosci; 2010 Oct;17(10):1355-6
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  • [Title] Trigeminal motor neuropathy with tongue fasciculations in a patient with chronic inflammatory demyelinating polyradiculoneuropathy.

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  • (PMID = 20615708.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Scotland
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93. Cheng C, Huo X, Ghovanloo M: Towards a magnetic localization system for 3-D tracking of tongue movements in speech-language therapy. Conf Proc IEEE Eng Med Biol Soc; 2009;2009:563-6
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  • [Title] Towards a magnetic localization system for 3-D tracking of tongue movements in speech-language therapy.
  • This paper presents a new magnetic localization system based on a compact triangular sensor setup and three different optimization algorithms, intended for tracking tongue motion in the 3-D oral space.
  • A small permanent magnet, secured on the tongue by tissue adhesives, will be used as a tracer.
  • The magnetic field variations due to tongue motion are detected by a 3-D magneto-inductive sensor array outside the mouth and wirelessly transmitted to a computer.
  • [MeSH-major] Communication Aids for Disabled. Magnetics / instrumentation. Movement / physiology. Signal Processing, Computer-Assisted / instrumentation. Telemetry / instrumentation. Tongue / physiology. Transducers

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  • (PMID = 19964478.001).
  • [ISSN] 1557-170X
  • [Journal-full-title] Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
  • [ISO-abbreviation] Conf Proc IEEE Eng Med Biol Soc
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / RC1 EB010915
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS698842; NLM/ PMC4470905
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94. Terzis JK, Konofaos P: Novel use of C7 spinal nerve for Moebius. Plast Reconstr Surg; 2010 Jul;126(1):106-17
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  • Tongue neurotization was performed in two instances.
  • Postoperatively, the patients' speech intelligibility improved as well as tongue motility and bulk.

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  • (PMID = 20595861.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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95. Okano J, Suzuki S, Shiota K: Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice. Toxicol Appl Pharmacol; 2007 May 15;221(1):42-56
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  • It was found that apoptotic cell death increased not only in the epithelium of the palatal shelves but also in the tongue primordium, which might affect tongue withdrawal movement during palatogenesis and impair the horizontal elevation of palatal shelves.
  • [MeSH-minor] Animals. Antineoplastic Agents / administration & dosage. Antineoplastic Agents / toxicity. Blotting, Western. Cell Cycle Proteins / metabolism. Embryo, Mammalian / abnormalities. Embryo, Mammalian / metabolism. Embryo, Mammalian / ultrastructure. Epithelial Cells / drug effects. Epithelial Cells / pathology. Epithelial Cells / ultrastructure. Female. Fetal Development / drug effects. In Situ Nick-End Labeling. Intubation, Gastrointestinal. Jaw / drug effects. Jaw / physiopathology. Male. Maxilla / abnormalities. Maxilla / ultrastructure. Mice. Mice, Inbred ICR. Microscopy, Electron, Scanning. Movement / drug effects. Palate / abnormalities. Palate / ultrastructure. Pregnancy. Tongue / abnormalities. Tongue / drug effects


96. Borges L, Rex KL, Chen JN, Wei P, Kaufman S, Scully S, Pretorius JK, Farrell CL: A protective role for keratinocyte growth factor in a murine model of chemotherapy and radiotherapy-induced mucositis. Int J Radiat Oncol Biol Phys; 2006 Sep 1;66(1):254-62
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  • Palifermin administration suppressed weight loss and resulted in increased organ weight (salivary glands and small intestine), epithelial thickness (esophagus and tongue), and cellular proliferation (tongue and salivary glands).

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  • (PMID = 16904525.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Radiation-Sensitizing Agents; 126469-10-1 / Fibroblast Growth Factor 7; EC 2.7.1.- / keratinocyte growth factor receptor; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 2; Q20Q21Q62J / Cisplatin
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97. Eberhard ML, Mathison B, Bishop H, Handoo NQ, Hellstein JW: Zoonotic anatrichosomiasis in an Illinois resident. Am J Trop Med Hyg; 2010 Aug;83(2):342-4
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  • A 44-year-old immigrant from Mexico originally presented with a history of multiple oral ulcers and two submucosal nodules on the dorsal surface of the tongue.
  • An incisional biopsy was taken to assist with diagnosis.
  • The location of the worm within the oral mucosal epithelium also facilitated the diagnosis.

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  • (PMID = 20682879.001).
  • [ISSN] 1476-1645
  • [Journal-full-title] The American journal of tropical medicine and hygiene
  • [ISO-abbreviation] Am. J. Trop. Med. Hyg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Antunes LA, Kuchler EC, de Andrade Risso P, Maia LC: Oral chemical burns caused by self-medication in a child: case report. J Burn Care Res; 2009 Jul-Aug;30(4):740-3
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  • Some chemicals can cause burning in the mucosa of cheeks, lips, tongue, and palate.

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  • (PMID = 19506514.001).
  • [ISSN] 1559-047X
  • [Journal-full-title] Journal of burn care & research : official publication of the American Burn Association
  • [ISO-abbreviation] J Burn Care Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 1490-04-6 / Menthol; 339NCG44TV / Phenol; 3T8H1794QW / Eugenol; 4Z8Y51M438 / Procaine
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99. Kato IT, Pellegrini VD, Prates RA, Ribeiro MS, Wetter NU, Sugaya NN: Low-level laser therapy in burning mouth syndrome patients: a pilot study. Photomed Laser Surg; 2010 Dec;28(6):835-9
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  • MATERIALS AND METHODS: Eleven subjects with a total of 25 sites (tongue, lower lip, upper lip, and palate) affected by a burning sensation were selected.
  • There was no statistical difference between the end of the treatment and the 6-week follow-up, except for the tongue site.

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  • (PMID = 21142725.001).
  • [ISSN] 1557-8550
  • [Journal-full-title] Photomedicine and laser surgery
  • [ISO-abbreviation] Photomed Laser Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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100. Schwarz EC, Thompson JM, Connor NP, Behan M: The effects of aging on hypoglossal motoneurons in rats. Dysphagia; 2009 Mar;24(1):40-8
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  • If present, these changes might help explain alterations at the neuromuscular junction and changes in the contractile properties of tongue muscle that have been reported in older rats.
  • Hypoglossal motoneurons were retrograde-labeled with injections of Cholera Toxin beta into the genioglossus muscle of the tongue and visualized using immunocytochemistry.

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  • (PMID = 18716837.001).
  • [ISSN] 1432-0460
  • [Journal-full-title] Dysphagia
  • [ISO-abbreviation] Dysphagia
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC005935; United States / NIDCD NIH HHS / DC / R01DC008149; United States / NIDCD NIH HHS / DC / R01 DC008149-02; United States / NIA NIH HHS / AG / R01 AG018760; United States / NIDCD NIH HHS / DC / R01DC005935; United States / NIDCD NIH HHS / DC / R01 DC008149-01A1; United States / NIDCD NIH HHS / DC / DC008149-02; United States / NIDCD NIH HHS / DC / DC008149-01A1; United States / NIA NIH HHS / AG / R01AG18760; United States / NIDCD NIH HHS / DC / R01 DC008149
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS51391; NLM/ PMC2644735
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