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1. Karonidis A, Rigby HS, Orlando A: Collagenosis Nuchae: a case report of a rare and often misdiagnosed condition. J Plast Reconstr Aesthet Surg; 2007;60(3):320-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CN is a rare benign soft tissue tumour that arises from the posterior cervical subcutaneous tissue with predilection for the interscapular and paraspinal regions.
  • The true incidence of CN is probably higher than recognised and CN should be in the differential diagnosis of head and neck lesions.
  • Histological examination is required for the diagnosis.
  • Careful total excision provides cure and accurate diagnosis.
  • [MeSH-major] Fibroma / diagnosis. Head and Neck Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 17293293.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 10
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2. Ogundiran TO, Ademola SA, Oluwatosin OM, Akang EE, Adebamowo CA: Primary osteogenic sarcoma of the breast. World J Surg Oncol; 2006;4:90
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  • BACKGROUND: Primary extra-osseous osteogenic sarcomas have been reported in many tissues of the body but their occurrence in the breast is extremely rare.
  • It can arise as a result of osseous metaplasia in a pre-existing benign or malignant neoplasm of the breast or as non-phylloides sarcoma from the soft tissue of a previously normal breast.
  • The histology report of core-needle biopsy of the mass showed a malignant neoplasm comprising islands of chondroblastic and osteoblastic stromal cells.
  • This report changed the diagnosis from carcinoma to osteogenic sarcoma of the breast.
  • Sections from the mastectomy specimen confirmed the diagnosis of osteogenic sarcoma.
  • CONCLUSION: A diagnosis of osteogenic sarcoma of the breast was made based on histology report and after excluding an osteogenic sarcoma arising from underlying ribs and sternum.

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  • (PMID = 17156481.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
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3. Sarikcioglu L, Demirel BM, Ozsoy U, Gurer EI, Oguz N, Ucar Y: Angiolipoma located inside the obturator canal and supplied by the umbilical artery. Ann Anat; 2007;189(1):75-8
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  • Microscopically the benign soft tissue tumor was characterized by lobules of mature adipocytes and densely distributed networks of small and larger blood vessels, thus resembling typical histological features of an angiolipoma.

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  • (PMID = 17319612.001).
  • [ISSN] 0940-9602
  • [Journal-full-title] Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
  • [ISO-abbreviation] Ann. Anat.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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4. Agostini T, Catelani C, Acocella A, Franchi A, Bertolai R, Sacco R, Lazzeri D, Shokrollahi K: Spindle cell liposarcoma of the face: case report and literature review. Br J Dermatol; 2010 Sep;163(3):638-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Liposarcoma is a common soft tissue sarcoma accounting for approximately 20% of all mesenchymal tumours across all ages.
  • Recently, collaborative research in the specialties of pathology and genetics has led to the delineation of several tumour variants with different behaviours and prognoses, one of which includes the very rare spindle cell liposarcoma (SCL) subtype.
  • We present the first case of an SCL arising in the subcutaneous tissue of the forehead of a 78-year-old man.
  • In light of the rarity of this tumour, we describe the tumour and its clinical and pathological characteristics and undertake a literature review to clarify the surgical management and prognosis of SCL, and increase awareness to avoid misdiagnosis of a benign soft tissue neoplasm.
  • [MeSH-major] Facial Neoplasms / pathology. Liposarcoma / pathology

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  • [Copyright] © 2010 The Authors. Journal Compilation © 2010 British Association of Dermatologists.
  • (PMID = 20456346.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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5. Delaney D, Diss TC, Presneau N, Hing S, Berisha F, Idowu BD, O'Donnell P, Skinner JA, Tirabosco R, Flanagan AM: GNAS1 mutations occur more commonly than previously thought in intramuscular myxoma. Mod Pathol; 2009 May;22(5):718-24
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  • Mutation detection plays an important role in diagnostic pathology, not only in providing a tissue diagnosis, but also in predicting response to antitumourigenic agents.
  • Intramuscular myxoma is a rare benign soft tissue neoplasm that occurs sporadically and less commonly in association with fibrous dysplasia (Mazabraud's syndrome).
  • Mutations were detected in two cases where a diagnosis of low-grade myxofibrosarcoma had been favoured over intramuscular myxoma.
  • [MeSH-major] GTP-Binding Protein alpha Subunits, Gs / genetics. Myxoma / genetics. Polymerase Chain Reaction / methods. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Cold Temperature. DNA Mutational Analysis. Diagnosis, Differential. Fibrosarcoma / genetics. Fibrosarcoma / pathology. Humans. Mutation. Sensitivity and Specificity

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  • (PMID = 19287459.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.6.1.- / GNAS protein, human; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gs
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6. Diniz MB, Giro Elisa MA, Zuanon Angela CC, Costa CA, Hebling J: Congenital epulis: a rare benign tumor in the newborn. J Indian Soc Pedod Prev Dent; 2010 Jul-Sep;28(3):230-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital epulis: a rare benign tumor in the newborn.
  • Congenital epulis (CE) of the newborn is a rare benign soft tissue tumor that presents at birth.
  • A decisive diagnosis is made by histopathologic analysis as other newborn lesions can be incorrectly diagnosed as CE.
  • [MeSH-major] Gingival Neoplasms / congenital. Gingival Neoplasms / pathology

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  • (PMID = 21157060.001).
  • [ISSN] 0970-4388
  • [Journal-full-title] Journal of the Indian Society of Pedodontics and Preventive Dentistry
  • [ISO-abbreviation] J Indian Soc Pedod Prev Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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7. Naka N, Joyama S, Tsukamoto Y, Yoshioka K, Hashimoto N, Ujiiye T, Hayashi T, Kawase M, Mano M, Ishiguro S, Myoui A, Ueda T, Yoshikawa H, Araki N, Itoh K: Quantification of SSX mRNA expression in human bone and soft tissue tumors using nucleic acid sequence-based amplification. J Mol Diagn; 2005 May;7(2):187-97
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  • [Title] Quantification of SSX mRNA expression in human bone and soft tissue tumors using nucleic acid sequence-based amplification.
  • The SSX family proteins have been considered new members of the cancer/testis antigens because of the restricted expression in testis among normal tissues and the activation in a wide range of cancers.
  • We have developed a competitive nucleic acid sequence-based amplification (NASBA) assay to analyze SSX mRNA expression in 211 bone and soft tissue tumors.
  • The copy numbers of SSX mRNA per mug of total RNA in tumor tissues were widely distributed, ranging logarithmically from 0.6 to 6.6.
  • We found that malignant tumors showed significantly higher expression of SSX mRNA than benign tumors (P < 0.0001).
  • [MeSH-major] Bone Neoplasms / genetics. Neoplasm Proteins / genetics. RNA, Messenger / analysis. Repressor Proteins / genetics. Self-Sustained Sequence Replication. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Animals. COS Cells. Child. Female. Gene Expression. Humans. Male. Middle Aged. RNA, Neoplasm / analysis. RNA, Neoplasm / metabolism

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  • (PMID = 15858142.001).
  • [ISSN] 1525-1578
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Repressor Proteins; 164289-47-8 / synovial sarcoma X breakpoint proteins
  • [Other-IDs] NLM/ PMC1867521
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8. LeCorn DW, Bhattacharyya I, Vertucci FJ: Peripheral ameloblastoma: a case report and review of the literature. J Endod; 2006 Feb;32(2):152-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Peripheral ameloblastoma is a rare, benign odontogenic tumor that histologically resembles an intraosseous ameloblastoma but develops in the soft tissues of the gingiva and mucosa and exhibits an innocuous clinical behavior.
  • The peripheral ameloblastoma should be included in the differential diagnosis of a gingival lesion clinically resembling any of the myriads of entities seen on the gingiva including a pyogenic granuloma, peripheral giant cell granuloma, or parulis/gumboil.
  • We believe this case highlights the need for submitting excised tissue for microscopic examination.
  • [MeSH-major] Ameloblastoma / pathology. Gingival Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Maxilla. Middle Aged. Neoplasm Recurrence, Local

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  • (PMID = 16427467.001).
  • [ISSN] 0099-2399
  • [Journal-full-title] Journal of endodontics
  • [ISO-abbreviation] J Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 11
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9. Mentzel T, Dei Tos AP, Sapi Z, Kutzner H: Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol; 2006 Jan;30(1):104-13
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  • [Title] Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases.
  • Perivascular neoplasms comprise traditionally glomus tumor and hemangiopericytoma (HPC).
  • Whereas glomus tumor represents a well-defined entity, the existence of HPC as a separate entity has been questioned because a number of neoplasms of different lines of differentiation are characterized by a HPC-like vascular growth pattern.
  • A large series of myopericytoma of skin and soft tissues has been analyzed to further characterize the clinicopathologic spectrum of this entity.
  • Fifty-four cases of myopericytoma of skin and soft tissues were retrieved and the histology reviewed.
  • In 20 cases, the neoplasms were confined to the dermis, in 6 cases an extension into the subcutis was seen, and 24 as well as 4 cases arose in subcutaneous and deep soft tissue, respectively.
  • Histologically, in all cases, numerous thin-walled vessels and a concentric, perivascular arrangement of ovoid, plump spindled to round myoid tumor cells was seen.
  • However, a broad morphologic spectrum ranging from hypocellular, fibroma-like (3 cases), myofibroma-like (2 cases), angioleiomyoma-like (12 cases), and HPC-like neoplasms (13 cases) to classic myopericytomas (14 cases) and immature, cellular lesions (2 cases) was noted.
  • In addition, 2 neoplasms with focal glomoid features, 5 intravascular, and 1 malignant myopericytomas were found.
  • Despite marginal or incomplete excision in 23 of 46 cases, only 2 neoplasms (1 malignant and 1 intravascular myopericytoma) recurred locally (within 1 and 4 years, respectively).
  • Despite overlapping morphologic features to angioleiomyoma and myofibroma, myopericytoma represents a distinct perivascular, myoid neoplasm of skin and soft tissues, characterized by a broad morphologic spectrum of concentrically, perivascularly growing myoid tumor cells that stain positively for ASMA and often for h-caldesmon, whereas desmin is usually negative.
  • Most cases of myopericytoma behave in a benign fashion, but local recurrences and rarely metastases may occur in atypical and malignant neoplasms.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasms, Vascular Tissue / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Angiomyoma / pathology. Diagnosis, Differential. Female. Glomus Tumor / pathology. Hemangiopericytoma / metabolism. Hemangiopericytoma / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Myofibroma / pathology

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  • (PMID = 16330949.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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10. Klijanienko J, Caillaud JM, Lagacé R: Cytohistologic correlations in schwannomas (neurilemmomas), including "ancient," cellular, and epithelioid variants. Diagn Cytopathol; 2006 Aug;34(8):517-22
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  • Schwannoma accounts for one of the most common benign mesenchymal neoplasms of soft tissues.
  • Original cytologic diagnosis was schwannoma in 13 (38.2%) cases, benign soft tissue tumor in 11 (32.4%), pleomorphic adenoma in 2 (6%) cases, angioma in 1 (2.9%) case, nodular fasciitis in 1 (2.9%) case, suspicious in 3 (8.8%) cases, and not satisfactory in 3 (8.8%) cases.
  • Similarly, cyto-nuclear atypia was more frequent in classical subtype than in other subtypes.
  • Schwannoma should be differentiated from well-differentiated malignant peripheral nerve sheath tumor, neurofibroma, and pleomorphic adenoma, in the last instance particularly for head and neck lesions.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Reproducibility of Results

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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16850489.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Sargenti-Neto S, Brazão-Silva MT, do Nascimento Souza KC, de Faria PR, Durighetto-Júnior AF, Loyola AM, Cardoso SV: Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions. Br J Oral Maxillofac Surg; 2009 Jan;47(1):62-4
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  • [Title] Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions.
  • Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue.
  • [MeSH-major] Granular Cell Tumor / pathology. Lip Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Genital Neoplasms, Female / surgery. Humans. Neoplasm Recurrence, Local. Perineum / pathology. Perineum / surgery

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  • (PMID = 18976838.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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12. Dong MJ, Zhou GY: [Imaging diagnosis of hemangioma in infants]. Shanghai Kou Qiang Yi Xue; 2008 Apr;17(2):221-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Imaging diagnosis of hemangioma in infants].
  • Hemangioma is the most commonly benign tumor of soft tissue tumors in infants.
  • In this article, the current situation of application with all imaging examinations used in diagnosis of hemangioma is reviewed.
  • [MeSH-major] Hemangioma / diagnosis

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  • (PMID = 18470434.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Ausmus GG, Piliang MP, Bergfeld WF, Goldblum JR: Soft-tissue perineurioma in a 20-year-old patient with neurofibromatosis type 1 (NF1): report of a case and review of the literature. J Cutan Pathol; 2007 Sep;34(9):726-30
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  • [Title] Soft-tissue perineurioma in a 20-year-old patient with neurofibromatosis type 1 (NF1): report of a case and review of the literature.
  • BACKGROUND: Perineurioma is a rare benign soft-tissue tumor composed of cells showing differentiation toward the perineurial cells of the nerve sheath.
  • Although mutations in the neurofibromatosis 2 (NF2) gene have been documented in this tumor, there is no known association between perineuriomas and type 1 or 2 NF.
  • METHODS: This is the first report of a case of soft-tissue perineurioma occurring in a patient with NF1.
  • RESULTS: Histopathologic examination revealed a 2.0-cm well-circumscribed, spindle-cell neoplasm with slender, elongated, bipolar, wavy cytoplasmic processes and wavy, elongated nuclei in a hyalinized stroma with focal myxoid areas.
  • Perineuriomas can be confused with other spindle-cell neoplasms, and relevant features and immunohistochemistry of these lesions are outlined.
  • [MeSH-major] Nerve Sheath Neoplasms / pathology. Neurofibromatosis 1 / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Female. Humans. Mucin-1 / metabolism. Thorax. Tomography, X-Ray Computed. Treatment Outcome


14. Manor E, Sion-Vardy N, Nash M, Bodner L: Angiomyoma of buccal vestibule: a rare case with a normal karyotype. J Laryngol Otol; 2007 Dec;121(12):1210-2
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  • Angiomyoma is an uncommon, benign, soft tissue tumour characterised by bundles of smooth muscle cells intermixed with numerous vascular channels, which usually develops in the lower extremities.
  • [MeSH-major] Angiomyoma / diagnosis. Mouth Neoplasms / diagnosis
  • [MeSH-minor] Adult. Cheek. Diagnosis, Differential. Humans. Male

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  • (PMID = 17524173.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Sherwani RK, Kumar A: Solitary fibrous tumour of the lower leg: an uncommon site with atypical histopathological features. BMJ Case Rep; 2010;2010
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  • [Title] Solitary fibrous tumour of the lower leg: an uncommon site with atypical histopathological features.
  • On local examination, the overlying skin was normal and the mass was soft to firm in consistency, non-tender and freely mobile with no fixity to underlying structures.
  • MRI revealed a lobulated mass with central areas of necrosis and no involvement of underlying muscles and neurovascular bundles suggesting a benign soft tissue tumour.
  • The tumour was totally excised and submitted for histopathological examination, which, along with immunopositivity for CD34, CD99 and focally for Bcl2, led to a confirmatory diagnosis of solitary fibrous tumour with atypical histopathological features of increased mitosis and necrosis.
  • [MeSH-major] Leg / pathology. Soft Tissue Neoplasms / pathology. Solitary Fibrous Tumors / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Male

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  • [Cites] Cancer. 2002 Feb 15;94(4):1057-68 [11920476.001]
  • [Cites] Am J Surg Pathol. 1998 Dec;22(12):1501-11 [9850176.001]
  • [Cites] BMC Surg. 2006;6:10 [16824225.001]
  • (PMID = 22791854.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC3027392
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16. Takahara M, Ichikawa R, Oda Y, Uchi H, Takeuchi S, Moroi Y, Kiryu H, Furue M: Desmoplastic fibroblastoma: a case presenting as a protruding nodule in the dermis. J Cutan Pathol; 2008 Oct;35 Suppl 1:70-3
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  • Desmoplastic fibroblastoma is a rare, benign, soft tissue tumor.
  • Histological examination from total excision showed a well-circumscribed tumor in the dermis, which comprised of spindle, oval and stellate cells arranged in a haphazard fashion, accompanied by abundant collagenous stroma and inconspicuous vasculature.
  • Immunohistochemically, the tumor cells were positive for vimentin, and focally positive for alpha-smooth muscle actin and muscle-specific actin, but negative for CD34, S-100 protein, desmin and beta-catenin.
  • We diagnosed this case as desmoplastic fibroblastoma arising in the dermis and superficial subcutaneous tissue.
  • [MeSH-major] Fibroma / pathology. Soft Tissue Neoplasms / pathology

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  • [Copyright] Copyright Blackwell Munksgaard 2008.
  • (PMID = 18544056.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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17. Laga AC, Tajirian AL, Islam MN, Bhattacharyya I, Cohen DM, Plamondon CJ, Robinson-Bostom L: Myopericytoma: report of two cases associated with trauma. J Cutan Pathol; 2008 Sep;35(9):866-70
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  • Myopericytoma is a rare, recently described tumor demonstrating a hemangiopericytoma-like vascular pattern.
  • We present two cases of myopericytoma associated with trauma: a 64-year-old man who developed several nodules on his nose four months after sustaining multiple abrasions to his forehead and nose, and a 72-year-old woman with a solitary growth in the alveolar ridge of unknown duration.
  • Despite sharing morphologic features with angioleiomyoma, myofibroma and glomus tumor, myopericytoma is thought to represent a distinct perivascular myoid neoplasm of skin and soft tissues.
  • The tumor is characterized by a radial and perivascular arrangement of ovoid, spindled to round neoplastic cells that are immunoreactive to alpha-smooth muscle actin, often for h-caldesmon as well as smooth muscle myosin-heavy chain, and usually negative for desmin antibodies.
  • Most cases of myopericytoma are benign, however, local recurrence and malignancy have recently been reported, Myopericytoma can be multifocal involving a single or multiple anatomic regions, and tends to occur in dermal and superficial soft tissues of adults primarily on the extremities.
  • Our cases are unusual examples of myopericytoma manifesting as multiple nodules on the nose, and a solitary growth on the buccal mucosa after trauma.
  • [MeSH-major] Hemangiopericytoma / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology. Wounds and Injuries / complications
  • [MeSH-minor] Actins / metabolism. Aged. Biomarkers, Tumor / metabolism. Calcium-Binding Proteins / metabolism. Female. Humans. Male. Microfilament Proteins / metabolism. Middle Aged. Mouth Mucosa / injuries. Myosin Heavy Chains / metabolism. Nose / injuries. Treatment Outcome

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  • (PMID = 18494828.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Microfilament Proteins; 0 / calponin; EC 3.6.4.1 / Myosin Heavy Chains
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18. Minagawa T, Matsushita K, Shimada R, Takayama H, Hiraga R, Uehara T, Murata Y: Aggressive angiomyxoma mimicking inguinal hernia in a man. Int J Clin Oncol; 2009 Aug;14(4):365-8
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  • Local excision was performed, with a preoperative diagnosis of benign soft tissue tumor.
  • Histopathological diagnosis revealed aggressive angiomyxoma (AAM), and no recurrence was observed 6 months after surgery.
  • AAM is a rare tumor which most commonly occurs in the pelvis or perineum of premenopausal women, with extremely rare cases in men.
  • The findings from previously reported cases and our case suggest that AAM should be considered in patients with an inguinal or scrotal swelling with a suspicious soft tissue tumor.
  • [MeSH-major] Hernia, Inguinal / diagnosis. Myxoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
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19. Murphy A, Williams J: Posterior interosseous nerve palsy caused by lipoma: A case report. Can J Plast Surg; 2009;17(4):e42-4
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  • Lipomas are benign soft tissue neoplasms that occur commonly in subcutaneous tissue.

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  • (PMID = 21119834.001).
  • [ISSN] 1918-1507
  • [Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique
  • [ISO-abbreviation] Can J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2827290
  • [Keywords] NOTNLM ; Forearm / Lipoma / Posterior interosseous nerve palsy
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20. Wu CW, Chi HP, Chiang FY, Hsu YC, Chan LP, Kuo WR: Giant lipoma arising from deep lobe of the parotid gland. World J Surg Oncol; 2006;4:28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Lipomas are common benign soft tissue neoplasms but they are found very rarely in the deep lobe of parotid gland.

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  • (PMID = 16740172.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1481629
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21. Nigri G, Dente M, Valabrega S, Beccaria G, Aurello P, D'Angelo F, Di Marzo F, Ramacciato G: Giant inframuscular lipoma disclosed 14 years after a blunt trauma: a case report. J Med Case Rep; 2008;2:318
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Lipoma is the most frequent benign tumor of the soft tissue.
  • Although the diagnosis is mostly clinical, imaging tools are useful to confirm the adipose nature of the lesion and to define its anatomic border.

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  • (PMID = 18826615.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2569952
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22. Ui M, Ogawa K: Subdeltoid lipoma: a case with symptoms mimicking glenohumeral instability and subacromial impingement. Orthopedics; 2010 Jun;33(6):443
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  • Lipoma is the most frequently occurring benign soft tissue tumor in the shoulder and the axillary region in middle-aged and older persons, yet few such lipoma cases have been associated with clinical symptoms.
  • A 38-year-old right-handed man presented with an enlarged feeling and a painful back-and-forth popping in his left shoulder.
  • Magnetic resonance imaging showed a homogenous tumor in the subdeltoid that was isointense relative to the subcutaneous fat and fluid collection in the hypertrophic subacromial bursa.
  • As the tumor was considered from the clinical and imaging findings to be attributable to all clinical symptoms, it was resected en bloc with a satisfactory result.
  • Histopathologically, the tumor showed typical features of a simple lipoma.
  • [MeSH-major] Lipoma / diagnosis. Muscle Neoplasms / diagnosis. Shoulder Dislocation / diagnosis. Shoulder Impingement Syndrome / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Shoulder

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20806760.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Lim KJ, Moon JH, Yoon DY, Cha JH, Lee IJ, Min SJ: Angiomyofibroblastoma arising from the posterior perivesical space: a case report with MR findings. Korean J Radiol; 2008 Jul-Aug;9(4):382-5
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  • Angiomyofibroblastoma is a rare benign soft tissue neoplasm that predominantly occurs in the genital region of middle-aged women.
  • [MeSH-major] Angiofibroma / diagnosis. Angiomyoma / diagnosis. Magnetic Resonance Imaging. Vaginal Neoplasms / diagnosis

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  • (PMID = 18682679.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627271
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24. Jani DR, Chawda J, Sundaragiri SK, Parmar G: Mucocele--a study of 36 cases. Indian J Dent Res; 2010 Jul-Sep;21(3):337-40
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  • BACKGROUND: Mucocele is one of the most common benign soft tissue tumor present in the oral cavity.
  • The clinical data were recorded and histopathologic diagnosis was made.
  • RESULTS: A diagnosis of mucocele was established in 36 cases with male-to-female ratio of 1.77:1.

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  • (PMID = 20930340.001).
  • [ISSN] 1998-3603
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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25. Eckardt AM, Kokemüller H, Flemming P, Schultze A: Recurrent ameloblastoma following osseous reconstruction--a review of twenty years. J Craniomaxillofac Surg; 2009 Jan;37(1):36-41
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  • BACKGROUND: The adequate therapy of ameloblastoma may require a compromise between the least destructive treatment possible of a benign tumour and a sufficiently radical method to prevent recurrences.
  • The primary reconstruction of bones and/or soft tissues, which is likely to be performed especially for benign processes is threatened by recurrences.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Reconstructive Surgical Procedures
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bone Transplantation. Child. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Mandibular Neoplasms / pathology. Mandibular Neoplasms / surgery. Maxillary Neoplasms / pathology. Maxillary Neoplasms / surgery. Middle Aged. Retrospective Studies. Surgical Flaps. Young Adult

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  • (PMID = 19022680.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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26. Sabah M, Cummins R, Leader M, Kay E: Leiomyosarcoma and malignant fibrous histiocytoma share similar allelic imbalance pattern at 9p. Virchows Arch; 2005 Mar;446(3):251-8
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  • Formalin-fixed, paraffin-embedded tissue from 45 soft tissue sarcomas was analysed for allelic imbalance/loss of heterozygosity (AI/LOH) of chromosome 9.
  • The specimens consisted of 17 cases of soft tissue leiomyosarcoma (LMS), 4 cases of cutaneous LMS, 22 cases of conventional malignant fibrous histiocytoma (MFH) and 2 cases of angiomatoid fibrous histiocytoma.
  • DNA was microdissected from normal and neoplastic tissues.
  • The frequency of allelic imbalance at different loci on chromosome 9p was analysed in LMS and MFH and then compared with values previously examined in synovial sarcoma and malignant peripheral nerve sheath tumour.
  • This locus may point to the existence of a genetically altered tumour suppressor gene involved in the pathogenesis of LMS and MFH.
  • Our results support the hypothesis that MFHs may represent a morphological pathway in tumour progression of LMSs.
  • [MeSH-major] Chromosomes, Human, Pair 9 / genetics. DNA, Neoplasm / genetics. Histiocytoma, Benign Fibrous / genetics. Leiomyosarcoma / genetics. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Allelic Imbalance. Humans. Immunohistochemistry. Loss of Heterozygosity. Microsatellite Repeats. Nerve Sheath Neoplasms / genetics. Polymerase Chain Reaction. Sarcoma, Synovial / genetics

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  • (PMID = 15731925.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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27. Nakashima K, Yamada N, Yoshida Y, Yamamoto O: Solitary sclerotic neurofibroma of the skin. Am J Dermatopathol; 2008 Jun;30(3):278-80
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  • Solitary neurofibroma of the skin is a benign soft tissue tumor.
  • Clinically, it is a flesh-colored, slow-growing, soft tumor and sometimes shows diverse histological patterns.
  • Our findings suggest that mast cells may have played a role in the formation of the sclerotic regions of the current tumor.
  • [MeSH-major] Neurofibroma / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Aged. Collagen / metabolism. Dermis / pathology. Female. Humans. Mast Cells / pathology. Sclerosis / metabolism. Sclerosis / pathology. Subcutaneous Tissue / pathology

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  • (PMID = 18496433.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
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28. Sari A, Tunakan M, Bolat B, Cakmakçi H, Ozer E: Lipofibromatosis in a two-year-old girl: a case report. Turk J Pediatr; 2007 Jul-Sep;49(3):319-21
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  • Lipofibromatosis is a recently described rare benign soft tissue tumor of childhood.
  • The tumor has a high rate of non-destructive recurrence, but there is no metastatic potential.
  • [MeSH-major] Fibroma / pathology. Neoplasm Recurrence, Local / surgery

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  • (PMID = 17990590.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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29. Bobbio A, Mazzeo A, Carbognani P, Rusca M: An unusual case of calcifying fibrous pseudotumour of the cervicothoracic junction. Eur J Cardiothorac Surg; 2008 Nov;34(5):1123-5
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  • Calcifying fibrous pseudotumour is a rare benign tumour of soft tissue origin, occasionally encountered in the thoracic cavity; surgical resection is considered the treatment of choice.
  • At surgery the tumour was found to circumferentially entrap the left subclavian artery and its removal involved segmental artery resection and reconstruction by autologous saphenous vein graft.

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  • (PMID = 18755598.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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30. Rohilla S, Yadav RK, Dhaulakhandi DB: Lipoma of Guyon's canal causing ulnar neuropathy. J Orthop Traumatol; 2009 Jun;10(2):101-3
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  • Lipoma is a benign soft tissue tumor which rarely causes neuropathy.

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31. Athwal GS, Bueno RA, Bansal M, Mintz DN, Athanasian EA: Intra-articular fibroma of tendon sheath involving the scapholunate and radiocarpal joints. Skeletal Radiol; 2006 Aug;35(8):599-602
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  • Fibroma of tendon sheath is an uncommon benign soft tissue tumor with a predilection for the hand.
  • Magnetic resonance imaging demonstrated a heterogeneous and lobulated mass with nonspecific signal characteristics closely associated with the scapholunate interval and the volar wrist soft tissues.
  • The tumor is discussed and the relevant literature is reviewed.
  • [MeSH-major] Fibroma / pathology. Soft Tissue Neoplasms / pathology. Wrist Joint / pathology

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  • (PMID = 16283174.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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32. Mentzel T, Kutzner H: Reticular and plexiform perineurioma: clinicopathological and immunohistochemical analysis of two cases and review of perineurial neoplasms of skin and soft tissues. Virchows Arch; 2005 Oct;447(4):677-82
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  • [Title] Reticular and plexiform perineurioma: clinicopathological and immunohistochemical analysis of two cases and review of perineurial neoplasms of skin and soft tissues.
  • Perineurioma represents a recently described and relatively rare neoplasm in the spectrum of benign peripheral nerve sheath tumours composed of perineurial cells staining immunohistochemically positive for epithelial membrane antigen (EMA).
  • In addition to intraneural, extraneural and sclerosing perineurioma, rare variants of perineurioma may occur, and their knowledge is important in the differential diagnosis of mesenchymal tumours of different lines of differentiation and clinically more aggressive neoplasms.
  • We present a case of deep-seated reticular perineurioma arising on the upper arm of a 34-year-old female and a case of a dermal plexiform perineurioma arising on the lower lip of a 60-year-old female.
  • The diagnosis was confirmed in both cases immunohistochemically; neoplastic cells stained positively for EMA and for the newly described perineurial markers, claudin-1 and glut-1.
  • The morphological spectrum and the differential diagnosis of perineurial neoplasms of skin and soft tissues are discussed.
  • [MeSH-major] Nerve Sheath Neoplasms / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Claudin-1. Diagnosis, Differential. Female. Fibroma / pathology. Glucose Transporter Type 1 / metabolism. Humans. Immunohistochemistry. Lipoma / pathology. Membrane Proteins / metabolism. Middle Aged. Mucin-1 / metabolism. S100 Proteins / metabolism. Sarcoma / pathology

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  • (PMID = 16133356.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CLDN1 protein, human; 0 / Claudin-1; 0 / Glucose Transporter Type 1; 0 / Membrane Proteins; 0 / Mucin-1; 0 / S100 Proteins
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33. Rau T, Soeder S, Olk A, Aigner T: Parosteal lipoma of the thigh with cartilaginous and osseous differentiation: an osteochondrolipoma. Ann Diagn Pathol; 2006 Oct;10(5):279-82
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  • Lipomas are very common benign soft tissue neoplasms.
  • Mature cartilage and bone arising in a lipoma is a rare event and is mostly associated with a parosteal localization of the neoplasm.
  • The occurrence of at least 4 distinct directions of mesenchymal cell differentiation within a benign neoplasia underlines the concept of multilineage differentiation of pluripotent mesenchymal stem cells.
  • Such a multidirectional potential was recently well established in vitro in stem cells present in adult adipocytic tissue.
  • [MeSH-major] Bone and Bones / pathology. Cartilage / pathology. Lipoma / pathology. Periosteum / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adipocytes / pathology. Aged. Cell Differentiation. Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Humans. Male. Mesenchymal Stromal Cells / pathology. Ossification, Heterotopic / pathology. Thigh

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  • (PMID = 16979520.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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34. Domanski HA, Mertens F, Panagopoulos I, Akerman M: Low-grade fibromyxoid sarcoma is difficult to diagnose by fine needle aspiration cytology: a cytomorphological study of eight cases. Cytopathology; 2009 Oct;20(5):304-14
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  • BACKGROUND: Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon neoplasm with bland morphology and an indolent clinical course, although metastases may develop in approximately 5-10% of the cases.
  • The diagnosis of LGFMS can be difficult to render from fine needle aspiration cytology (FNAC) alone because of morphological overlap with other spindle cell and myxoid lesions.
  • Tumours arose in the deep soft tissues of the thigh (n = 5), shoulder girdle (n = 1) or upper arm (n = 1) and one in the subcutaneous tissue of the abdominal wall.
  • Cytological features included clusters of bland spindle and round/polygonal cells embedded in a collagenous and myxoid matrix along with dissociated, uniform or slightly/moderately pleomorphic spindle cells, bare nuclei and fragments of collagen and myxoid tissue in varying proportions.
  • In three cases, the diagnosis was inconclusive with regard to benignity or malignancy, while three were erroneously diagnosed as benign spindle cell lesions.
  • Although the diagnosis was suggested on three of six CNB, these presented similar diagnostic problems.
  • CONCLUSIONS: There were no cytomorphological findings in FNAC to allow for a clear cut separation of LGFMS from other spindle cell or myxoid lesions, but high-grade sarcoma could be excluded.
  • Surgical (incisional or excisional) biopsy or, alternatively, examination of RT-PCR for the FUS/CREB3L or FUS/CREB3L1 fusion transcripts may be necessary to obtain a correct diagnosis.
  • [MeSH-major] Biopsy, Fine-Needle. Fibroma. Sarcoma. Soft Tissue Neoplasms

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  • (PMID = 18637810.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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35. Ritchie DA, Aniq H, Davies AM, Mangham DC, Helliwell TR: Hibernoma--correlation of histopathology and magnetic-resonance-imaging features in 10 cases. Skeletal Radiol; 2006 Aug;35(8):579-89
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  • OBJECTIVE, DESIGN AND PATIENTS: Hibernoma is an uncommon, slow-growing, benign soft-tissue tumour resembling brown adipose tissue.
  • [MeSH-major] Magnetic Resonance Imaging. Neoplasms, Adipose Tissue / pathology

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  • (PMID = 16642344.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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36. Pichi B, Manciocco V, Marchesi P, Pellini R, Ruscito P, Vidiri A, Covello R, Spriano G: Rhabdomyoma of the parapharyngeal space presenting with dysphagia. Dysphagia; 2008 Jun;23(2):202-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rhabdomyoma is an exceedingly rare soft tissue benign tumor of skeletal muscle origin classified into cardiac and extracardiac types based on location.
  • Adult rhabdomyomas are rare, but morphologically characteristic, benign mesenchymal tumors with mature skeletal muscle differentiation that in 90% of cases arise in the head and neck region, mainly in the mucosa of the oropharynx, nasopharynx, and larynx, from the branchial musculature of third and fourth branchial arches.
  • [MeSH-major] Deglutition Disorders / etiology. Oropharyngeal Neoplasms / complications. Oropharyngeal Neoplasms / pathology. Rhabdomyoma / complications. Rhabdomyoma / pathology

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  • (PMID = 17965913.001).
  • [ISSN] 0179-051X
  • [Journal-full-title] Dysphagia
  • [ISO-abbreviation] Dysphagia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Moretti VM, de la Cruz M, Lackman RD, Fox EJ: Fibroma of tendon sheath in the knee: a report of three cases and literature review. Knee; 2010 Aug;17(4):306-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fibroma of tendon sheath (FTS) is a rare and benign soft-tissue tumor.
  • Physical exam for knee FTS commonly reveals painful range of motion (50%), decreased range of motion (42%), and a palpable non-tender mass (33%).
  • MRI of FTS usually reveals a well-defined soft-tissue mass, with low signal on T1, variable signal on T2, and variable enhancement.
  • Despite its rarity, this lesion should be included in the differential diagnosis of a knee mass on physical exam or imaging, especially if it is painful, benign appearing, and present in a middle-aged male.
  • [MeSH-major] Fibroma / pathology. Knee Joint / pathology. Soft Tissue Neoplasms / pathology. Tendons / pathology

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20347314.001).
  • [ISSN] 1873-5800
  • [Journal-full-title] The Knee
  • [ISO-abbreviation] Knee
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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38. Nuruddin M, Osmani M, Mudhar HS, Fernando M: Orbital lipofibromatosis in a child: a case report. Orbit; 2010 Dec;29(6):360-2
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  • PURPOSE: Lipofibromatosis is a rare, benign, soft tissue tumor that typically involves extremities particularly in children.
  • Orbital imaging showed a soft tissue mass superolateral to the globe with possible infiltration into the lacrimal gland and lateral rectus muscle.
  • Histopathological examination revealed that the lesion consisted of adipose tissue with fibroblastic elements, being consistent with a diagnosis of lipofibromatosis.
  • Diagnosis can be confirmed by histopathological analysis.
  • [MeSH-major] Fibroma / pathology. Lipoma / pathology. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery
  • [MeSH-minor] Biopsy, Needle. Blepharoptosis / diagnosis. Blepharoptosis / etiology. Child. Female. Follow-Up Studies. Humans. Immunohistochemistry. Ophthalmologic Surgical Procedures / methods. Rare Diseases. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 21158580.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Xu Y, Jing Y, Ma S, Ma F, Wang Y, Ma W, Li Q: Primary angioleiomyoma in the sellar region: a case report and literature review. Clin Neuropathol; 2010 Jan-Feb;29(1):21-5
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  • OBJECTIVE: Angioleiomyoma (vascular leiomyomas, angiomyoma) is a rare, benign soft tissue tumor which consists of a mixture of well-differentiated smooth muscle cells and thick-walled vessels.
  • Gross total resection of the tumor was then performed.
  • The pertinent literature regarding the features of this tumor was reviewed and discussed.
  • CONCLUSIONS: Intracranial angioleiomyoma is a benign soft tissue tumor with excellent prognosis.
  • Early diagnosis of this tumor is difficult.
  • [MeSH-major] Angiomyoma / pathology. Brain / pathology. Brain Neoplasms / pathology
  • [MeSH-minor] Adrenocorticotropic Hormone / metabolism. Early Diagnosis. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neurologic Examination. Prognosis

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  • (PMID = 20040329.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 9002-60-2 / Adrenocorticotropic Hormone
  • [Number-of-references] 14
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40. Adnani A, Chellaoui M, Chat L, Dafiri R: [Unusual appearance of axillary lipoblastoma of infancy]. J Radiol; 2005 Sep;86(9 Pt 1):1043-5
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  • Lipoblastoma is an uncommon benign soft tissue tumor of infancy and early childhood with a predilection for the extremities.
  • CT and MRI can confirm the presence of fat components in the tumor.
  • By showing lipoblastoma proliferation, histology confirms the diagnosis.
  • [MeSH-major] Axilla / pathology. Lipoma / congenital. Soft Tissue Neoplasms / congenital
  • [MeSH-minor] Biopsy. Female. Humans. Infant. Magnetic Resonance Imaging. Neoplasm Recurrence, Local / pathology. Tomography, X-Ray Computed

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  • (PMID = 16224347.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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41. Woźniak AW, Nowaczyk MT, Osmola K, Golusinski W: Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol; 2010 Jun;267(6):845-9
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  • Benign osteoblastoma is a rarely seen tumor of the facial bones.
  • The authors present a case of a 30-year-old man with a tumor of the mandibular body and ramus.
  • The histopathological diagnosis was one of osteoblastoma.
  • Postoperative recurrence with soft tissue infiltration suggested an osteosarcoma radiologically, but the histological examination again revealed the presence of an osteoblastoma.
  • A second recurrence occured in the pharyngo-glossal region and this time the tumor was histologically diagnosed as an osteoblastoma, but with foci of well-differentiated osteosarcoma.
  • While osteoblastomas are rare, and their sarcomatous change even rarer, our experience with this case lead us to suggest that a therapeutic preventative approach, involving both chemotherapy and total excision of the tumor, is the regime to adopt with osteoblastomas which involve soft tissues and have radiological features suggesting malignancy.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Mandibular Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Osteoblastoma / pathology. Osteosarcoma / pathology
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Lung Neoplasms / pathology. Lung Neoplasms / secondary. Male. Mandible / pathology. Mandible / surgery. Radiography, Panoramic. Radiotherapy, Adjuvant. Reoperation

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  • (PMID = 20012077.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
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42. Archontaki M, Korkolis DP, Arnogiannaki N, Hatzijiannis S, Dendrinos P, Megapanos C, Kassotakis D, Kokkalis G: Histologically malignant solitary fibrous tumour of the anterior thoracic wall: a case report and review of the literature. Case Rep Med; 2010;2010:257167
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  • [Title] Histologically malignant solitary fibrous tumour of the anterior thoracic wall: a case report and review of the literature.
  • Solitary fibrous tumour (SFT) is a rare oncological entity that most often arises in the pleura.
  • Over the past 10 years, the tumour has been described at numerous extrapleural locations.
  • Although extrapleural SFT usually behaves as a benign soft tissue tumour, it can also present with a more aggressive local behavior, including locoregional recurrence or metastasis.
  • In that case, a multidisciplinary approach is required for accurate diagnosis and proper management.

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  • (PMID = 20589090.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2892660
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43. Frison L, Goudot P, Yachouh J: [Soft tissue myxoma of the face]. Rev Stomatol Chir Maxillofac; 2010 Feb;111(1):21-4
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  • [Title] [Soft tissue myxoma of the face].
  • [Transliterated title] Tumeurs myxoïdes des tissus mous de la face.
  • Myxoid tumors are a group of heterogeneous lesions with a voluminous myxoid matrix, which may affect any tissue in the body.
  • Localization in facial soft tissues is very rare.
  • These tumors are benign but with a high potential for local aggressiveness and recurrence.
  • [MeSH-major] Facial Neoplasms / diagnosis. Myxoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Diagnostic Imaging. Facial Bones / pathology. Humans. Neoplasm Recurrence, Local / pathology. Odontogenic Tumors / diagnosis. Skull Neoplasms / diagnosis

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  • (PMID = 20060989.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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44. Thomas S, Revadi PS, Jeyachandran P, Muley PR: Painless angioleiomyoma: a case report with review of literature. Indian J Pathol Microbiol; 2006 Jul;49(3):440-1
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  • A 55 year old male, who presented with a painless swelling of six months duration on his thigh, was clinically diagnosed to have a benign soft tissue neoplasm.
  • Histological examination of the excision biopsy specimen revealed a benign tumour of the vascular smooth muscle, which was diagnosed as angioleiomyoma.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 17001916.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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45. Bennani L, Amine B, Aktaou S, Hajjaj-Hassouni N: [True intra-articular lipoma in a rheumatoid knee]. Presse Med; 2008 Apr;37(4 Pt 1):610-3
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  • INTRODUCTION: Lipoma is a frequent benign tumor of the soft tissue, but intra-articular locations are rare.
  • DISCUSSION: True intra-articular lipoma, found mostly in the knee, is extremely rare and usually occurs de novo.
  • MRI can provide a positive and differential diagnosis, but nonetheless requires histologic confirmation.
  • [MeSH-minor] Female. Humans. Lipoma / diagnosis. Lipoma / surgery. Middle Aged. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery. Synovitis / complications

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  • (PMID = 18191369.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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46. Cyran CC, Fu Y, Raatschen HJ, Rogut V, Chaopathomkul B, Shames DM, Wendland MF, Yeh BM, Brasch RC: New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues. J Magn Reson Imaging; 2008 Mar;27(3):581-9
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  • [Title] New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues.
  • PURPOSE: To compare three new macromolecular polyethylene glycol (PEG) -core dendrimeric gadolinium(Gd)-based MRI contrast agents for their applicability in quantitative assays of endothelial leakiness and tissue vascular density for the differentiation of cancer from normal soft tissues.
  • 100 cm(3)) and tumor fractional plasma volumes (%) based on a two-compartment kinetic model were performed for skeletal muscle and tumors.
  • 100 cm(3)) in normal soft tissue microvessels allowing successful differentiation (P < 0.05) of cancers from normal muscle.
  • PEG(12,000)-Gen4-(Gd-DOTA) leaked in tumors and in normal muscle (K(PS) = 51 +/- 26 and K(PS) = 21 +/- 18 microL/min .
  • CONCLUSION: MRI assays of vascular endothelial leakiness using new PEG-core, (Gd-DOTA)-conjugated macromolecular contrast agents proved applicable for the differentiation of human breast cancer from normal soft tissue.
  • [MeSH-major] Contrast Media. Gadolinium. Heterocyclic Compounds. Magnetic Resonance Imaging. Neoplasms, Experimental / diagnosis. Organometallic Compounds
  • [MeSH-minor] Animals. Breast Neoplasms / diagnosis. Endothelium, Vascular. Female. Humans. Neoplasm Transplantation. Rats. Rats, Nude. Transplantation, Heterologous

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  • (PMID = 18219614.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 082923; United States / NCI NIH HHS / CA / R01 CA 103850
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Heterocyclic Compounds; 0 / Organometallic Compounds; 92923-44-9 / gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; AU0V1LM3JT / Gadolinium
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47. Klenke FM, Merkle T, Fellenberg J, Abdollahi A, Huber PE, Gebhard MM, Ewerbeck V, Sckell A: A novel model for the investigation of orthotopically growing primary and secondary bone tumours using intravital microscopy. Lab Anim; 2005 Oct;39(4):377-83
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  • Although up to 85% of the most frequently occurring malignant solid tumours, such as lung and prostate carcinomas, metastasize into the bone, and despite the knowledge that a tumour's course may be altered by its surrounding tissue, there is no adequate experimental model available enabling the investigation of orthotopically grown bone tumours in vivo.
  • Intravital microscopy is an internationally accepted experimental method, used in various acute and chronic animal models, that enables qualitative and quantitative analysis of the angiogenesis, microcirculation, growth behaviour, etc. of various benign and malignant tissues.
  • Additionally, tissue samples can be taken after termination of the in vivo experiments for further ex vivo investigation (histology, immunohistochemistry, molecular biology, etc.
  • Severe combined immunodeficient mice were fitted with a cranial window preparation where the calvaria served as the site for orthotopic implantation of the solid human tumours Saos-2 osteosarcoma (primary) and A 549 lung carcinoma and PC-3 prostate carcinoma (secondary).
  • Histological assessment confirmed the data obtained in vivo, showing typical tumour growth with infiltration of the surrounding osseous and soft tissues.
  • This novel model serves as a valuable tool in understanding the biology of primary and secondary bone tumours in physiological and pathophysiological situations, with implications for the most areas of tumour therapy such as chemotherapy, radiation and antiangiogenesis.
  • [MeSH-major] Bone Neoplasms / pathology. Osteosarcoma / pathology
  • [MeSH-minor] Animals. Lung Neoplasms / pathology. Male. Mice. Mice, SCID. Microscopy, Fluorescence. Microscopy, Video. Neoplasm Transplantation. Neovascularization, Pathologic / pathology. Prostatic Neoplasms / pathology

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  • (PMID = 16197704.001).
  • [ISSN] 0023-6772
  • [Journal-full-title] Laboratory animals
  • [ISO-abbreviation] Lab. Anim.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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48. Liao KS, Huang WT, Yang SF, Chien SH, Hsieh TJ, Chai CY, Wu CC: Intramuscular low-grade fibromyxoid sarcoma: a case report. Kaohsiung J Med Sci; 2009 Aug;25(8):448-54
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  • Low-grade fibromyxoid sarcoma (LGFMS) is a rare neoplasm that commonly arises in the deep soft tissues of the lower extremities, particularly in the thigh.
  • Although LGFMS has a deceptively benign histologic appearance, local recurrence and late metastases have frequently been reported.
  • Diagnosis of LGFMS is still difficult because of its characteristic bland-looking histologic features that can be confused with other benign or low-grade fibromyxoid lesions.
  • Although immunohistochemical staining can offer an overview of the differential diagnosis of myxoid tumors of soft tissue, it is sometimes limited for diagnosis of LGFMS.
  • However, recent cytogenetic and molecular analyses have provided significant improvements in the diagnosis of LGFMS.
  • In conclusion, diagnosis of LGFMS can be challenging in routine practice in surgical pathology because of its bland-looking features.
  • [MeSH-major] Fibrosarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 19605340.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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49. Capodiferro S, Maiorano E, Scarpelli F, Favia G: Fibrolipoma of the lip treated by diode laser surgery: a case report. J Med Case Rep; 2008;2:301
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  • INTRODUCTION: Several neoplasms of the adipose tissue can involve the soft tissues of the head and neck region.
  • These neoplasms are mainly treated surgically and an accurate histological examination is mandatory for a precise diagnosis.
  • This approach allowed adequate resection of the neoplasm with minimal damage to the adjacent tissues, thus reducing post-surgical scarring.
  • CONCLUSION: Diode laser surgery for the treatment of benign lesions of the oral mucosa appears to be a convenient alternative to conventional blade surgery and has proved to be effective for the excision of fibrolipoma of the lip.

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  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2547114
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50. Kumazoe H, Nagamatsu Y, Nishi T, Kimura YN, Nakazono T, Kudo S: Dumbbell-shaped thoracic hibernoma: computed tomography and magnetic resonance imaging findings. Jpn J Radiol; 2009 Jan;27(1):37-40
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  • Hibernoma is an uncommon, benign soft tissue tumor that arises in brown adipose tissue.
  • We report the unique appearance of a rare thoracic wall hibernoma, which appeared as a dumbbell-shaped lipomatous tumor across an intercostal region.
  • [MeSH-major] Lipoma / diagnostic imaging. Soft Tissue Neoplasms / diagnostic imaging

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  • [ISSN] 1867-1071
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
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51. Laskin WB, Fetsch JF, Lasota J, Miettinen M: Benign epithelioid peripheral nerve sheath tumors of the soft tissues: clinicopathologic spectrum of 33 cases. Am J Surg Pathol; 2005 Jan;29(1):39-51
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  • [Title] Benign epithelioid peripheral nerve sheath tumors of the soft tissues: clinicopathologic spectrum of 33 cases.
  • Benign epithelioid peripheral nerve sheath tumors (BEPNSTs) have not been fully characterized, and their relationship to conventional schwannoma and neurofibroma has not been satisfactorily established.
  • Tumors consisted of trabeculae, loosely arranged nodules, and cohesive nests of epithelioid tumor cells immersed in collagenous, myxohyaline, or chiefly myxoid stroma.
  • A bland spindled cell component comprising 5% to 40% of the tumor was noted in 15 cases.
  • Immunohistochemical reactivity for Schwann cell-related markers in tumor cells included S-100 protein (20 of 20 cases), collagen type IV (10 of 10), laminin (8 of 8), nerve growth factor receptor, p75(7 of 8), CD57 (6 of 9), and glial fibrillary acidic protein (8 of 15).
  • CD34-positive fibroblast-like cells were identified in all 12 neoplasms tested.
  • Follow-up for 18 patients (median interval, 13.5 years), including 4 patients with tumors exhibiting cytologic atypia, revealed a nondestructive recurrence or persistent disease in 3 patients whose tumors lacked atypia, but no evidence of metastatic spread or tumor-related death.
  • BEPNSTs are usually small neoplasms located in superficial soft tissue and have an excellent prognosis after complete local excision.
  • [MeSH-major] Epithelioid Cells / pathology. Nerve Sheath Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / metabolism. Child. Child, Preschool. DNA, Neoplasm / analysis. Female. Humans. Immunoenzyme Techniques. Loss of Heterozygosity. Male. Middle Aged. Mitotic Index. Neurofibromin 1 / genetics. Neurofibromin 1 / metabolism. Neurofibromin 2 / genetics. Neurofibromin 2 / metabolism. Polymerase Chain Reaction

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  • (PMID = 15613855.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Neurofibromin 1; 0 / Neurofibromin 2
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52. Wang Y, Yang J, Gao Y, Zhao XL, Li HZ, Yao Z: [Relationship between raf kinase inhibitor protein and metastasis of ovarian carcinoma]. Zhonghua Fu Chan Ke Za Zhi; 2009 Jul;44(7):522-8
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  • Assays of cell proliferation, soft-agar colony formation, cell adhesion, and cell invasion in vitro were used to examine the malignant phenotypes of the transfected cells.
  • (1) The expression levels of RKIP protein in ovarian carcinoma tissues from patients were found to be reduced than those in ovarian benign tumor and borderline tumor.
  • CONCLUSION: RKIP could inhibits the metastasis, but also the growth of ovarian cancer cells. patients were found to be reduced than those in ovarian benign tumor and borderline tumor.
  • [MeSH-major] Extracellular Signal-Regulated MAP Kinases / metabolism. Mitogen-Activated Protein Kinase Kinases / metabolism. Ovarian Neoplasms / metabolism. Ovarian Neoplasms / pathology. Phosphatidylethanolamine Binding Protein / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Cell Line, Tumor. Cell Proliferation. Female. Genes, Tumor Suppressor. Genetic Vectors. Humans. Immunohistochemistry. Middle Aged. Neoplasm Invasiveness. Neoplasm Metastasis. Phosphorylation. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Transfection. Young Adult

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  • (PMID = 19957553.001).
  • [ISSN] 0529-567X
  • [Journal-full-title] Zhonghua fu chan ke za zhi
  • [ISO-abbreviation] Zhonghua Fu Chan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Phosphatidylethanolamine Binding Protein; 0 / RNA, Messenger; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 2.7.12.2 / Mitogen-Activated Protein Kinase Kinases
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53. Ramirez RN, Otsuka NY, Apel DM, Bowen RE: Desmoid tumor in the pediatric population: a report of two cases. J Pediatr Orthop B; 2009 May;18(3):141-4
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  • [Title] Desmoid tumor in the pediatric population: a report of two cases.
  • Desmoid tumors are benign tumors that cause considerable morbidity and are prone to recurrence.
  • They tend to extensively infiltrate surrounding tissues, complicating the treatment.
  • We present the report of two cases of desmoid tumor in the pediatric population.
  • The first patient had tumor that necessitated removal of most of the anterior compartment of his leg.
  • The tumor in the second case was intimately involved with neurovascular structures and, therefore adjuvant treatment including chemotherapy and repeat surgery was necessary.
  • [MeSH-major] Fibromatosis, Aggressive / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Child. Combined Modality Therapy. Humans. Infant. Leg / surgery. Male. Neoplasm Recurrence, Local. Tendon Transfer. Treatment Outcome

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  • (PMID = 19322113.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Weber KL, Peabody T, Frassica FJ, Mott MP, Parsons TW 3rd: Tumors for the general orthopedist: how to save your patients and practice. Instr Course Lect; 2010;59:579-91
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  • It is likely that most orthopaedic surgeons will see a patient with a benign or malignant musculoskeletal tumor sometime during their career.
  • However, because of the rarity of these entities, many surgeons may benefit from a review of how to evaluate a patient with a bone lesion or soft-tissue mass.
  • A logical approach is necessary in evaluating imaging studies as well as in the workup of children and adults with a possible tumor.
  • If the treatment algorithms lead to a conclusive diagnosis of a benign bone tumor, benign soft-tissue mass, or metastatic bone disease, the orthopaedic surgeon may choose to definitively treat the patient.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Cysts / diagnosis. Joint Diseases / pathology. Orthopedics. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 20415407.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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55. Hondar Wu HT, Chen W, Lee O, Chang CY: Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review. Clin Imaging; 2006 Jan-Feb;30(1):32-6
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  • [Title] Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review.
  • The imaging findings (X-ray and MRI) and patterns of calcification of five patients with pathologically proven soft-tissue chondroma were correlated with histopathology.
  • Four showed calcifications: curvilinear, punctuate, mixed curvilinear, and punctuate patterns, and the other one with a dystrophic or homogenous dense pattern showed hypointensity on T1- and T2-weighted MR imaging.
  • Soft-tissue chondroma is a rare, benign soft-tissue tumor.
  • It should be differentiated from other soft-tissue masses, especially malignancy.
  • [MeSH-major] Chondroma / pathology. Finger Phalanges / pathology. Soft Tissue Neoplasms / pathology. Toe Phalanges / pathology. Wrist Joint / pathology

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  • (PMID = 16377482.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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56. Hsieh TJ, Wang CK, Tsai KB, Chen YW: Pilomatricoma: magnetic resonance imaging and pathological evaluation. J Comput Assist Tomogr; 2008 Mar-Apr;32(2):320-3
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  • Pilomatricoma is an asymptomatic, slowly growing, benign skin tumor that is typically located in the regions of head and neck.
  • Our case revealed late enhancement in the dynamic magnetic resonance imaging study that is a common pattern more in a benign soft tissue tumor and caused dramatic uptake in the bone scintigraphy.
  • [MeSH-major] Hair Diseases / diagnosis. Magnetic Resonance Imaging / methods. Pilomatrixoma / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18379325.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Al-Daraji WI: Granular perineurioma: the first report of a rare distinctive subtype of perineurioma. Am J Dermatopathol; 2008 Apr;30(2):163-8
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  • Perineurioma represents a relatively recently described neoplasm in the spectrum of benign peripheral nerve sheath tumors composed of perineurial cells staining immunohistochemically positive for epithelial membrane antigen.
  • Although intraneural, extraneural and sclerosing perineurioma, rare variants of perineurioma, do occur, and knowledge of them is important in the differential diagnosis of mesenchymal tumors of different lines of differentiation and more importantly if their clinical course differs from that of other perineuriomas.
  • We report herein the first case in the world literature of granular perineurioma arising in the dermal and subcutaneous tissues of the trunk of a 28-year-old female.
  • The diagnosis was confirmed morphologically and immunohistochemically.
  • Interestingly, the granular component of this large tumor (4.5 cm in maximum diameter) was negative for S100, but positive for NKI-C3.
  • The morphology, immunohistochemistry, and the clinical behavior for this tumor and the differential diagnoses are discussed.
  • [MeSH-major] Lipoma / pathology. Nerve Sheath Neoplasms / pathology. Peripheral Nervous System Neoplasms / pathology. Sciatic Nerve / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Rare Diseases. Risk Assessment. Thoracic Wall

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  • [CommentIn] Am J Dermatopathol. 2008 Dec;30(6):636 [19033949.001]
  • (PMID = 18360122.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Li G, Wu YT, Chen Y, Li TJ, Gao Y, Zhang J, Zhang ZY, Ma XC: Soft-tissue osteoma in the pterygomandibular space: report of a rare case. Dentomaxillofac Radiol; 2009 Jan;38(1):59-62
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  • [Title] Soft-tissue osteoma in the pterygomandibular space: report of a rare case.
  • Osteoma is a slow-growing, benign and uncommon neoplasm located primarily in the region of the maxillofacial skeleton.
  • An extraskeletal soft-tissue osteoma is exceedingly rare.
  • Here, we report a case of soft-tissue osteoma occurring in the pterygomandibular space in a 66-year-old woman.
  • Intraoperatively, the masses were completely surrounded by soft tissues with no attachment to the bone.
  • Histological examination indicated the diagnosis of cancellous osteoma.
  • [MeSH-major] Head and Neck Neoplasms / radiography. Osteoma / radiography. Soft Tissue Neoplasms / radiography

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  • (PMID = 19114426.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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59. Keser S, Bayar A, Numanoğlu G: An unusual cause for anterior knee pain: strangulated intra-articular lipoma. Knee Surg Sports Traumatol Arthrosc; 2005 Oct;13(7):585-8
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  • Lipoma is the most frequently encountered benign soft tissue tumor.
  • Magnetic resonance imaging revealed an intra-articular tumor of the knee joint.
  • Arthroscopic intervention and subsequent histological examination resulted in the diagnosis of strangulated lipoma originating from infrapatellar fat pad.
  • [MeSH-major] Knee Joint / pathology. Lipoma / diagnosis
  • [MeSH-minor] Adult. Arthroscopy. Female. Humans. Joint Diseases / diagnosis. Joint Diseases / surgery. Magnetic Resonance Imaging. Pain / etiology. Patella / pathology

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  • [Cites] Knee Surg Sports Traumatol Arthrosc. 1996;4(3):154-6 [8961230.001]
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  • (PMID = 16208424.001).
  • [ISSN] 0942-2056
  • [Journal-full-title] Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
  • [ISO-abbreviation] Knee Surg Sports Traumatol Arthrosc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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60. Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J: Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour. Surgeon; 2006 Dec;4(6):378-83
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  • [Title] Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour.
  • BACKGROUND: The Buschke-Löwenstein tumour (BLT) or giant condyloma acuminata is a rare disease which affects the anogenital region.
  • Although histologically benign, it behaves in a malignant fashion, infiltrating the surrounding tissues.
  • The morbidity and mortality from this tumour is high, as is the risk of recurrence following treatment.
  • It lies on the continuum between the benign condylomata acuminata and squamous cell carcinoma.
  • CONCLUSION: Pre-operative chemoradiation has proved to be useful in management for histologically proven benign BLT
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Condylomata Acuminata / therapy. Neoadjuvant Therapy. Perineum / pathology. Perineum / surgery. Soft Tissue Neoplasms / therapy
  • [MeSH-minor] Abdominal Neoplasms / secondary. Abdominal Neoplasms / therapy. Adult. Anus Neoplasms / secondary. Anus Neoplasms / therapy. Carcinoma in Situ / pathology. Carcinoma in Situ / therapy. Carcinoma, Squamous Cell / therapy. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Fatal Outcome. Fluorouracil / administration & dosage. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Rectal Neoplasms / secondary. Rectal Neoplasms / therapy

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  • (PMID = 17152203.001).
  • [ISSN] 1479-666X
  • [Journal-full-title] The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
  • [ISO-abbreviation] Surgeon
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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61. Liu P, Ramachandran S, Ali Seyed M, Scharer CD, Laycock N, Dalton WB, Williams H, Karanam S, Datta MW, Jaye DL, Moreno CS: Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells. Cancer Res; 2006 Apr 15;66(8):4011-9
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  • Prostate cancer is the most commonly diagnosed noncutaneous neoplasm and second most common cause of cancer-related mortality in western men.
  • To investigate the mechanisms of prostate cancer development and progression, we did expression profiling of human prostate cancer and benign tissues.
  • We show that the SOX4 is overexpressed in prostate tumor samples compared with benign tissues by microarray analysis, real-time PCR, and immunohistochemistry.
  • We also show that SOX4 expression is highly correlated with Gleason score at the mRNA and protein level using tissue microarrays.
  • Stable transfection of SOX4 into nontransformed prostate cells enabled colony formation in soft agar, suggesting that, in the proper cellular context, SOX4 can be a transforming oncogene.
  • [MeSH-major] Cell Transformation, Neoplastic / genetics. High Mobility Group Proteins / genetics. Oncogenes. Prostatic Neoplasms / genetics. Trans-Activators / genetics
  • [MeSH-minor] Apoptosis / genetics. Cell Growth Processes / physiology. Cell Line, Transformed. Cell Line, Tumor. Gene Expression Profiling. Humans. Male. RNA, Small Interfering / genetics. Reverse Transcriptase Polymerase Chain Reaction. SOXC Transcription Factors. Transfection

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  • (PMID = 16618720.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / T32 GM008169; United States / NCI NIH HHS / CA / CA91435; United States / NCI NIH HHS / CA / K22-CA96560; United States / NIDDK NIH HHS / DK / DK60647; United States / NIGMS NIH HHS / GM / T32 GM008490; United States / NCI NIH HHS / CA / R01-CA106826
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / High Mobility Group Proteins; 0 / RNA, Small Interfering; 0 / SOX4 protein, human; 0 / SOXC Transcription Factors; 0 / Trans-Activators
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62. Bandyopadhyay S, Basturk O, Coban I, Thirabanjasak D, Liang H, Altinel D, Adsay NV: Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate. Am J Surg Pathol; 2009 Mar;33(3):425-9
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  • [Title] Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate.
  • The glandular units of invasive carcinoma are often well formed with well-polarized cells, appearing deceptively benign.
  • We recently noted isolated solitary ductal units (ISDs) in adipose tissue to be a reliable indicator of adenocarcinoma.
  • ISD was defined as a solitary gland lying individually in adipose tissue, either directly abutting adipocytes or separated from them by only a thin rim of fibromuscular tissue.
  • ISDs were often located in histologic sections taken for the evaluation of the retroperitoneal margin and pancreatic-free surfaces where adipose tissue is more abundant.
  • In conclusion, ISD lying in adipose tissue unaccompanied by other elements, present in 47.6% of pancreatic resections when peripancreatic soft tissues away from the tumor are sampled, is a very specific finding for carcinoma that may be instrumental in the diagnosis and staging of carcinoma as well as margin evaluation.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Pancreatitis / pathology

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  • (PMID = 19092633.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases.
  • BACKGROUND: The diagnosis of retroperitoneal lesions is one of the most difficult areas in surgical pathology.
  • Fine needle aspiration cytology has shown promising role in establishing the diagnosis in this region.
  • OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.
  • RESULTS: Out of 85 cases, 32 were of kidney, 27 of lymph nodes, 24 of retroperitoneal soft tissues, and two were of the adrenals.
  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).
  • CONCLUSIONS: USG-guided FNAC is an inexpensive, rapid, safe, and accurate procedure for the diagnosis of retroperitoneal masses.

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  • (PMID = 21938165.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168018
  • [Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum
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64. Oh JT, Choi SH, Ahn SG, Kim MJ, Yang WI, Han SJ: Vulvar lipomas in children: an analysis of 7 cases. J Pediatr Surg; 2009 Oct;44(10):1920-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Vulvar lipomas are a type of rare benign soft tissue tumor.
  • It is necessary to differentiate this tumor from an inguinal hernia.
  • Radiologic studies such as ultrasonography, computed tomography, and magnetic resonance imaging are useful for making the proper diagnosis.
  • [MeSH-major] Lipoma / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Age Factors. Child. Diagnosis, Differential. Female. Functional Laterality. Hernia, Inguinal / diagnosis. Humans. Korea / epidemiology. Magnetic Resonance Imaging / statistics & numerical data. Retrospective Studies. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery. Tomography, X-Ray Computed / statistics & numerical data. Treatment Outcome. Ultrasonography / statistics & numerical data

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  • (PMID = 19853747.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Sailon AM, Cappuccino G, Hameed M, Fleegler EJ: Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report. Eplasty; 2008;8:e38
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  • OBJECTIVE: This study describes a case of nodular fasciitis involving the hand and reviews the neoplasm's pertinent clinical, histologic, and pathologic features.
  • CONCLUSIONS: Nodular fasciitis is a self-limited, benign soft tissue tumor composed of fibroblasts and myofibroblasts that typically afflicts younger patients and rarely presents in the hand.
  • Because of its presentation, it can be easily mistaken for a malignant neoplasm.

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  • [Cites] Orthop Clin North Am. 2006 Jan;37(1):53-63 [16311111.001]
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  • (PMID = 18725954.001).
  • [ISSN] 1937-5719
  • [Journal-full-title] Eplasty
  • [ISO-abbreviation] Eplasty
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2491338
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66. Chadha M, Singh AP: Unusual knee swelling: a diagnostic dilemma. Arch Orthop Trauma Surg; 2007 Sep;127(7):593-6
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  • Haemangioma is a common benign soft tissue tumour.
  • An intramuscular haemangioma can be confused with other soft tissue swellings including abscess.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Muscle Neoplasms / diagnosis
  • [MeSH-minor] Child. Diagnosis, Differential. Edema / diagnosis. Humans. Knee. Male

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  • (PMID = 17165037.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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67. Tzanakis NE, Giannopoulos GA, Efstathiou SP, Rallis GE, Nikiteas NI: Angiomyofibroblastoma of the spermatic cord: a case report. J Med Case Rep; 2010;4:79
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  • INTRODUCTION: Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva.
  • At operation, a 4.5 cm well-circumscribed solid tumor was found adherent to the spermatic cord.
  • The tumor consisted of spindle-shaped cells proliferating in short fascicles between numerous medium-sized blood vessels with thin and hyalinized walls.
  • CONCLUSION: This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential.

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  • (PMID = 20202207.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2838917
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68. Ponce-Camacho MA, Diaz de Leon-Medina R, Miranda-Maldonado I, Garza-Guajardo R, Hernandez-Salazar J, Barboza-Quintana O: A 5-year-old girl with a congenital ganglioneuroma diagnosed by fine needle aspiration biopsy: a case report. Cytojournal; 2008;5:5
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  • INTRODUCTION: Ganglioneuroma is a rare, benign, neuroblastic tumor arising mainly from the central or peripheral autonomic nervous system, especially the sympathetic system.
  • The most affected anatomical sites are the posterior mediastinum, retroperitoneum, adrenal gland and head and neck soft tissue.
  • Laboratory routine tests were within normal limits, ultrasonography demonstrated a solid and well-circumscribed lesion in the soft tissues of the cervical region.
  • A diagnosis of ganglioneuroma was suggested.
  • Core biopsy and surgical resection confirmed this diagnosis.
  • CONCLUSION: Congenital ganglioneuroma of the cervical region is an uncommon soft tissue benign neoplasm of neuroblastic origin, and it should be considered in the differential diagnosis of head and neck pediatric soft tissue tumors.
  • Fine needle aspiration biopsy technique is a reliable method that can be used with confidence when dealing with pediatric soft tissue tumors.

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  • (PMID = 18373875.001).
  • [ISSN] 1742-6413
  • [Journal-full-title] CytoJournal
  • [ISO-abbreviation] Cytojournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2359765
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69. Kazakov DV, Hes O, Hora M, Sima R, Michal M: Primary intranodal cellular angiolipoma. Int J Surg Pathol; 2005 Jan;13(1):99-101
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  • Angiolipoma is a distinct, benign soft tissue tumor that most commonly occurs in young males as multiple small, subcutaneous, tender to painful nodules with predilection for the forearms.
  • Microscopically, the major portion of the lymph node was replaced by mature metaplastic adipose tissue.
  • Focally, areas with increased cellularity and a suggestion of solid growth of the endothelial cells were seen.
  • Lymph nodes are known to be a rare primary site of various tumors usually occurring in other organs.
  • The most recognized examples are pigmented nevi, palisading myofibroblastoma, various benign epithelial inclusions, serous cystic tumors of borderline malignancy, and hyperplastic mesothelial inclusions.
  • As we present in this report, angiolipoma is another neoplasm whose primary occurrence in the lymph node should not be misinterpreted as a metastatic tumor or malignant vascular tumor.
  • [MeSH-major] Angiolipoma / pathology. Lymph Nodes / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adipose Tissue / pathology. Aged. Antigens, CD31 / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Lymphatic Metastasis / diagnosis. Male. Metaplasia / pathology

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  • (PMID = 15735863.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor
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70. Tomihama RT, Lindskog DM, Ahrens W, Haims AH: Hibernoma: a case report demonstrating usefulness of MR angiography in characterizing the tumor. Skeletal Radiol; 2007 Jun;36(6):541-5
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  • [Title] Hibernoma: a case report demonstrating usefulness of MR angiography in characterizing the tumor.
  • Hibernoma is a rare, benign soft-tissue tumor composed of brown fat.
  • However, recent reports have focused upon the tumor vascularity of hibernomas.
  • We describe the only case in the literature which utilizes state of the art contrast enhanced MR angiography to clearly characterize the surface and intratumoral vessels to help confirm the diagnosis of a hibernoma and aid in the preoperative planning.
  • [MeSH-major] Lipoma / diagnosis. Magnetic Resonance Angiography
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Humans. Thigh

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  • (PMID = 17221278.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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71. Tavusbay C, Genç H, Haciyanli M, Gür OS, Ekinci N: [Glomus tumor of the stomach: a rare cause of upper gastrointestinal bleeding]. Ulus Travma Acil Cerrahi Derg; 2009 Jan;15(1):85-7
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  • [Title] [Glomus tumor of the stomach: a rare cause of upper gastrointestinal bleeding].
  • Glomus tumors are benign soft tissue neoplasms that usually arise in the skin of the extremities; however, those tumors are sometimes located in other sites such as gastrointestinal (GIS), respiratory, and genital tracts.
  • Herein, we report a case of a glomus tumor of the stomach in a 31-year-old female patient who presented with intermittent nausea, vomiting, hematemesis and melena for 2 months.
  • Immunohistochemical examination showed the glomus tumor.
  • Since the glomus tumor is essentially benign and does not need a radical surgical procedure, the most important aspect of this tumor is its histologic identification and differentiation from more common gastric lesions, especially from malignant tumors.
  • [MeSH-major] Gastrointestinal Hemorrhage / etiology. Glomus Tumor / complications. Soft Tissue Neoplasms / complications. Stomach Neoplasms / complications
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 19130345.001).
  • [ISSN] 1306-696X
  • [Journal-full-title] Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • [ISO-abbreviation] Ulus Travma Acil Cerrahi Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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72. Patsiaoura K, Anagnostou E, Benis N: Intramuscular myxoma of the nasal vestibule. Auris Nasus Larynx; 2010 Feb;37(1):100-2
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  • Intramuscular myxoma is an uncommon benign soft tissue neoplasm and a distinct histopathological entity within the heterogeneous group of myxomas.
  • The tumor was surgically removed and the patient is free of recurrence or complications 8 months after treatment.
  • To the very best of our knowledge, there is no report of this neoplasm located within the nasal and oral mimetic muscles.
  • [MeSH-major] Muscle, Skeletal / pathology. Myxoma / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Humans. Male. Middle Aged. Nasal Cavity. Otorhinolaryngologic Surgical Procedures. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery. Treatment Outcome

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19414229.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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73. Liu ZJ, Zhao Q, Zhang LJ: Extraskeletal osteochondroma near the hip: a pediatric case. J Pediatr Orthop B; 2010 Nov;19(6):524-8
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  • Extraskeletal osteochondroma near the hip is rare and its pathological diagnosis is based on radiological and histopathological examination.
  • It is vital that such a diagnosis be considered when a discrete, ossified mass is localized in soft tissues, even at atypical sites.
  • Differential diagnoses include myositis ossificans, a lipomatous lesion, a pseudomalignant osseous tumour, an ossifying fibromyxoid tumour, an extraskeletal chondroma with endochondral ossification, synovial (osteo) chondromatosis, tumoural calcinosis, a synovial sarcoma and an extraskeletal osteosarcoma.
  • Clinical awareness of this benign entity is important as no malignant transformation or metastasis has been reported.
  • [MeSH-major] Osteochondroma / pathology. Osteochondroma / surgery. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Biopsy, Needle. Child. Follow-Up Studies. Hip. Humans. Immunohistochemistry. Lumbosacral Region. Male. Neoplasm Staging. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20802344.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Ang WM, Yates P, Robbins P, Wood D: Recurrent benign solitary intraosseous schwannoma of the tibia. Orthopedics; 2008 Feb;31(2):176
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  • [Title] Recurrent benign solitary intraosseous schwannoma of the tibia.
  • Schwannomas (neurilemmomas) are benign neoplasms composed of well-differentiated Schwann cells and are usually found in the soft tissues.
  • We report the first case of a recurrent benign solitary intraosseous schwannoma of the tibia, and detail the clinical, radiological and histological findings.
  • [MeSH-major] Bone Neoplasms / radiography. Bone Neoplasms / surgery. Neoplasm Recurrence, Local / radiography. Neoplasm Recurrence, Local / surgery. Neurilemmoma / radiography. Neurilemmoma / surgery. Tibia / surgery

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  • (PMID = 19292192.001).
  • [ISSN] 0147-7447
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Lin TM, Chang HW, Wang KH, Kao AP, Chang CC, Wen CH, Lai CS, Lin SD: Isolation and identification of mesenchymal stem cells from human lipoma tissue. Biochem Biophys Res Commun; 2007 Oct 5;361(4):883-9
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  • [Title] Isolation and identification of mesenchymal stem cells from human lipoma tissue.
  • Lipoma is a benign neoplasm of normal fat cells that appears as a soft, movable swelling, often with a slight yellowish coloration.
  • Human mesenchymal stem cells (MSCs) that have been isolated from bone marrow, blood, and other adult tissues including adipose tissue have the potential to be useful candidates for therapy.
  • No literature had reported about stem cells from lipoma tissue.
  • Cells produced in early cultures display characteristics similar to those previously reported for multipotential stem cells, including a high frequency of anchorage-independent growth in soft agar and a lack of gap junctional intercellular communication in cell types with serpiginous morphology.

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  • (PMID = 17679141.001).
  • [ISSN] 0006-291X
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Rousseau A, Kujas M, van Effenterre R, Boch AL, Carpentier A, Leroy JP, Poirier J: Primary intracranial myopericytoma: report of three cases and review of the literature. Neuropathol Appl Neurobiol; 2005 Dec;31(6):641-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myopericytoma is a benign tumour generally arising in the subcutaneous and superficial soft tissues of the extremities.
  • Very few cases have been reported in other locations and intracranial examples are exceptional.
  • The tumour involved, respectively, the anterior cranial fossa, the orbital apex and the pineal region.
  • The other two are alive and well at 9 and 12 month follow-up respectively.
  • Myopericytoma is a recently described neoplasm, and it is likely that reappraisal of intracranial haemangiopericytoma with which it shares many histopathologic features will lead to more case reports of primary intracranial myopericytoma.
  • [MeSH-major] Brain Neoplasms / pathology. Hemangiopericytoma / pathology. Myofibromatosis / pathology

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  • (PMID = 16281913.001).
  • [ISSN] 0305-1846
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 24
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77. Wang W, Tavora F, Sharma R, Eisenberger M, Netto GJ: PSMA expression in Schwannoma: a potential clinical mimicker of metastatic prostate carcinoma. Urol Oncol; 2009 Sep-Oct;27(5):525-8
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  • OBJECTIVES: Radioimmunoscintigraphy using a radiolabeled antibody against prostate-specific membrane antigen (PSMA) is frequently used to detect prostate carcinoma (PCa) recurrence and metastasis to lymph nodes, soft tissues, and bone.
  • PSMA expression has been shown in occasional nonprostatic neoplasms (e.g., urothelial adenocarcinoma) and in the vasculatures of other malignancies.
  • PSMA expression has not been described in benign neoplasms.
  • PSMA expression was evaluated in tumor cells and lesional vessels.
  • RESULTS: All 11 SCH showed tumoral and or vascular staining; 7 (7/11) displayed both vascular and tumoral cell staining; the remaining 4 had only vascular staining (2/11) or tumor cell staining (2/11).
  • The extent of tumoral cell and vascular staining varied widely among lesions (tumor cells: focal in 8 and diffuse in 1; vascular: focal in 7, multifocal in 1, and diffuse in 1 lesion).
  • CONCLUSION: This is the first report of PSMA expression in a benign neoplasm.
  • Given our finding of frequent expression of PSMA in Schwannomas, they should be clinically considered in the differential diagnosis of a lesion that is positive on PSMA radioimmunoscintigraphy study performed during a metastatic work-up of PCa patient.
  • [MeSH-major] Antigens, Surface / biosynthesis. Biomarkers, Tumor / analysis. Glutamate Carboxypeptidase II / biosynthesis. Neurilemmoma / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Prostatic Neoplasms / diagnosis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / radionuclide imaging. Radionuclide Imaging

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  • (PMID = 18534872.001).
  • [ISSN] 1873-2496
  • [Journal-full-title] Urologic oncology
  • [ISO-abbreviation] Urol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / Biomarkers, Tumor; EC 3.4.17.21 / Glutamate Carboxypeptidase II; EC 3.4.17.21 / glutamate carboxypeptidase II, human
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78. Hsu TL, Changchien CC, Huang CC, Lin H: Angioleiomyoma originating from the ovary of an eleven-year-old premenarchal girl. Gynecol Obstet Invest; 2008;65(4):262-5
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  • BACKGROUND: Angioleiomyoma (ALM) is a rare, benign neoplasm involving the peripheral soft tissues.
  • The final pathologic report of the resected tumor was consistent with an ALM.
  • [MeSH-major] Angiomyoma / diagnosis. Angiomyoma / surgery. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / surgery

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  • [Copyright] (c) 2008 S. Karger AG, Basel
  • [CommentIn] Gynecol Obstet Invest. 2010;70(1):8-10 [20130412.001]
  • (PMID = 18196910.001).
  • [ISSN] 1423-002X
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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79. Majeski J: Elastofibroma: a subscapular mass. Am J Surg; 2008 Jul;196(1):93-4
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  • The tumor is situated under the inferior angle of the scapula when the arm and scapula are in the neutral position.
  • A chest computed tomography scan with contrast showed bilateral soft-tissue opacities below each scapula.
  • The radiologic diagnosis of a typical subscapular elastofibroma was confirmed by core-needle biopsy of each mass.
  • The radiologic and clinical diagnosis and surgical treatment of this benign soft-tissue tumor are discussed.
  • [MeSH-major] Fibroma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 18513699.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Holzheimer RG: Adverse events of sutures: possible interactions of biomaterials? Eur J Med Res; 2005 Dec 7;10(12):521-6
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  • Tissue reactions which might be associated with suture material have rarely been reported in the past.
  • After a long period without complications caused by suture material we observed 12 cases of unexpected tissue reactions after clean operations.
  • Our patients 3-8 weeks after uneventful elective clean operations (varicose vein, hernia, benign soft tissue tumor) had unexpected tissue reactions (inflammation, granuloma, extrusion, fistula, abscess) in the vicinity of Vicryl, suture material (8 cases with Vicryl, 4 cases with Vicryl plus.
  • After removal of the suture material and the granulomatous tissue wounds healed without any further disturbance.
  • These tissue reactions have been observed in patients with subcuticular sutures as well as in patients with deeper located vein ligatures.
  • For clarification evaluation of the tissue reactions of these biomaterials including possible interactions or combined reactions should be done.
  • [MeSH-major] Cyanoacrylates / adverse effects. Polyglactin 910 / adverse effects. Postoperative Complications / etiology. Sutures. Tissue Adhesives / adverse effects

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  • (PMID = 16356867.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Cyanoacrylates; 0 / Tissue Adhesives; 34346-01-5 / Polyglactin 910; 6701-17-3 / octyl 2-cyanoacrylate
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81. Nishiguchi T, Mochizuki K, Nakayama T, Inoue Y, Ohata K, Wakasa K: A case of synovial sarcoma in the perivertebral space of the neck: clinical presentation, radiological findings and histopathological description. Br J Radiol; 2008 Mar;81(963):e72-4
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  • We report a case of synovial sarcoma in the neck that was initially considered to be a benign soft-tissue tumour.
  • The mass also encased the right vertebral artery and this suggested a malignant soft-tissue tumour.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Sarcoma, Synovial / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Contrast Media. Diagnosis, Differential. Fatal Outcome. Female. Humans. Lung Neoplasms / secondary. Lymph Nodes. Magnetic Resonance Imaging. Neck. Neurofibroma / pathology. Tomography, X-Ray Computed

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  • (PMID = 18270287.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
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82. Ghazali N, Cascarini L, Norris P, Barrett AW, Lavery KM: Perivascular epithelioid cell tumor (PEComa) of the cheek. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jul;110(1):e26-31
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  • [Title] Perivascular epithelioid cell tumor (PEComa) of the cheek.
  • We present the unusual case of a perivascular epithelioid cell tumor (PEComa) occurring within the cheek of a 32-year-old woman.
  • It mainly affects the abdominopelvic region and rarely occurs in somatic soft tissue or skin.
  • To our knowledge, this is the first reported case of PEComa occurring in the facial cutaneous tissues.
  • Other possible diagnoses considered included benign mesenchymal tumors of smooth muscle or neural origin.
  • The tumor was completely excised, but in view of uncertainty as to how this entity would behave in an unusual location, lifelong follow up is recommended.
  • [MeSH-major] Cheek / pathology. Facial Neoplasms / diagnosis. Perivascular Epithelioid Cell Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Actins / analysis. Adult. Antigens, Neoplasm / analysis. Arterioles / pathology. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Follow-Up Studies. Humans. MART-1 Antigen. Muscle, Smooth, Vascular / pathology. Neoplasm Proteins / analysis

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20610292.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins
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83. Roebuck MM, Helliwell TR, Chaudhry IH, Kalogrianitis S, Carter S, Kemp GJ, Ritchie DA, Jane MJ, Frostick SP: Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities. Am J Clin Pathol; 2005 Mar;123(3):405-14
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  • [Title] Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
  • We defined the immunocytochemical expression of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in benign soft tissue neoplasms, fibromatoses, and sarcomas, together with the activity of gelatinase MMPs and TIMPs measured by zymography and reverse zymography in a subset of cases.
  • Fibromatoses and high-grade sarcomas showed greater MMP-1 expression than other groups, and endothelial MMP-2 expression was more extensive in sarcomas.
  • Differences in MMP and TIMP expression might be linked to the biologic behavior of soft tissue neoplasms.
  • [MeSH-major] Extremities / pathology. Fibroma / pathology. Matrix Metalloproteinases / metabolism. Neovascularization, Pathologic / pathology. Sarcoma / pathology. Soft Tissue Neoplasms / pathology. Tissue Inhibitor of Metalloproteinases / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cell Proliferation. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 15716237.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tissue Inhibitor of Metalloproteinases; EC 3.4.24.- / Matrix Metalloproteinases
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84. Rehders A, Stoecklein NH, Poremba C, Alexander A, Knoefel WT, Peiper M: Reexcision of soft tissue sarcoma: sufficient local control but increased rate of metastasis. World J Surg; 2009 Dec;33(12):2599-605
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  • [Title] Reexcision of soft tissue sarcoma: sufficient local control but increased rate of metastasis.
  • BACKGROUND: Assuming a benign tumor, soft tissue sarcomas are often treated by inadequate resection.
  • Therefore, it was our goal to evaluate the results of this treatment with particular respect to residual tumor.
  • The assessed endpoints were local recurrence-free survival, distant metastasis-free survival, and tumor-related mortality.
  • Residual tumor was detected in 43 patients (31%) and was significantly associated with reduced relapse-free and overall survival.
  • CONCLUSIONS: Despite an incomplete initial resection, reexcision enables local control similar to that in patients without residual tumor.
  • Still, these patients have a worse prognosis owing to an increased rate of distant metastasis; therefore, patients with soft tissue masses of unknown identity should be transferred to centers that specialize in treating sarcomas for adequate initial resection.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery. Sarcoma / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Reoperation. Survival Analysis. Young Adult

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  • [ErratumIn] World J Surg. 2010 Aug;34(8):1991
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  • (PMID = 19838751.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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85. Stone DU, Chodosh J: Epibulbar nodular fasciitis associated with floppy eyelids. Cornea; 2005 Apr;24(3):361-2
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  • CONCLUSIONS: Nodular fasciitis is a rare, benign, soft-tissue tumor that has not been previously reported in association with floppy eyelids.
  • [MeSH-major] Eyelid Diseases / diagnosis. Eyelids / pathology. Fasciitis / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 15778617.001).
  • [ISSN] 0277-3740
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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86. Menditti D, Laino L, Mezzogiorno A, Sava S, Bianchi A, Caruso G, Di Maio L, Baldi A: Oral benign fibrous histiocytoma: two case reports. Cases J; 2009;2:9343
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  • [Title] Oral benign fibrous histiocytoma: two case reports.
  • Fibrous histiocytoma is a benign soft tissue tumour arising as a fibrous mass everywhere in the human body.
  • We report two cases of benign fibrous histiocytoma that localized in the oral cavity.

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  • (PMID = 20066060.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804724
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87. Craig WD, Fanburg-Smith JC, Henry LR, Guerrero R, Barton JH: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics; 2009 Jan-Feb;29(1):261-90
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  • Retroperitoneal lesions represent a broad, diverse collection of entities; when they contain fat, the differential diagnosis, which ranges from benign to fully malignant lesions, substantially narrows.
  • Hibernoma is a rare benign soft-tissue tumor composed of brown fat.
  • Teratomas are neoplasms that originate in pluripotent cells--benign or malignant germ cells--that give rise to a wide spectrum of mature or immature tissues that are foreign to the location in which they arise and which demonstrate varying amounts of organ formation.
  • Myelolipoma, a benign tumor composed of mature fat and interspersed hematopoietic elements that resemble bone marrow, typically originate in an otherwise normal adrenal gland.
  • Angiomyolipoma is composed of varying admixtures of blood vessels, smooth muscle cells, and adipose tissue; any one or two of these elements may predominate.
  • [MeSH-major] Intra-Abdominal Fat / pathology. Intra-Abdominal Fat / radiography. Lipomatosis / diagnosis. Lipomatosis / pathology. Neoplasms, Adipose Tissue / diagnosis. Neoplasms, Adipose Tissue / pathology. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Neoplasms / pathology

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  • (PMID = 19168848.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Bernstein ML, Chung KC: Desmoplastic fibroma of the hand: case report. J Hand Surg Am; 2008 Oct;33(8):1405-8
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  • Desmoplastic fibroma is a benign tumor of the soft tissue and rarely of the bone.
  • We present a rare case of desmoplastic fibroma of the soft tissues of the hand that presented as a slow-growing, painless, well-encapsulated mass.
  • [MeSH-major] Fibroma, Desmoplastic / pathology. Hand. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Amputation / methods. Biopsy, Needle. Bone Neoplasms / pathology. Bone Neoplasms / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Fingers / surgery. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Rare Diseases. Risk Assessment. Treatment Outcome

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  • (PMID = 18929210.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / K42 AR053120
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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89. Patti R, Almasio PL, Di Vita G: Granular cell tumor of stomach: a case report and review of literature. World J Gastroenterol; 2006 Jun 7;12(21):3442-5
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  • [Title] Granular cell tumor of stomach: a case report and review of literature.
  • Granular cell tumor (GCT) was described for the first time by Abrikosoff in 1926.
  • It is a relatively rare neoplasm that may occur at many sites, but most commonly in the skin or soft tissues.
  • Gastric GCTs can be solitary or, more frequently, associated with other gastrointestinal localization.
  • Although GCTs are usually clinically and histologically benign, some malignant cases have been reported.
  • A correct preoperative diagnosis of this tumor can only be made in 50% of all patients and it is always based on endoscopic biopsy.
  • In this study, the authors reported a case of a 49-year-old woman with a solitary granular cell tumor of the stomach with infiltrative pattern, successfully treated with surgical resection.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery

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  • (PMID = 16733867.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC4087881
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90. Gupta SP, Agarwal A: Intraosseous neurilemmoma of L2 vertebra--a case report. Indian J Pathol Microbiol; 2005 Jul;48(3):367-9
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  • Intraosseous neurilemmoma (schwannoma) is a rare bone tumor with incidence less than 0.2% of all primary bone tumors.
  • It is a benign neoplasm arising from the schwann cells of the nerve sheath.
  • Computed tomograph revealed a large soft tissue component of the tumor mass with thecal sac compression.
  • A computed tomograph assisted needle biopsy revealed the tumor to be neurilemmoma.
  • Subsequently, during decompression, it was possible to shell out tumor from surrounding tissues.
  • Remaining tumor was curettedfrom bone and the cavity packed with autograft.
  • The aim of this article is to highlight intraosseous neurilemmoma as a possible differential diagnosis in bony tumors.
  • [MeSH-major] Lumbar Vertebrae / pathology. Neurilemmoma. Spinal Neoplasms

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  • (PMID = 16761755.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 4
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91. Rabban JT, Dal Cin P, Oliva E: HMGA2 rearrangement in a case of vulvar aggressive angiomyxoma. Int J Gynecol Pathol; 2006 Oct;25(4):403-7
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  • The histogenesis of aggressive angiomyxoma, an uncommon mesenchymal neoplasm of the vulvar, pelvic, and perineal soft tissues, is poorly understood, although the neoplastic cells exhibit a myofibroblastic phenotype.
  • HMGA2 involvement has also been described in a variety of benign gynecologic mesenchymal neoplasms.
  • [MeSH-major] HMGA2 Protein / genetics. Myxoma / genetics. Vulvar Neoplasms / genetics

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  • (PMID = 16990720.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HMGA2 Protein
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92. Miettinen M, Makhlouf HR, Sobin LH, Lasota J: Plexiform fibromyxoma: a distinctive benign gastric antral neoplasm not to be confused with a myxoid GIST. Am J Surg Pathol; 2009 Nov;33(11):1624-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plexiform fibromyxoma: a distinctive benign gastric antral neoplasm not to be confused with a myxoid GIST.
  • A great majority of gastric mesenchymal tumors are gastrointestinal stromal tumor (GIST).
  • A rare group of non-GISTs include myxoid mesenchymal neoplasms.
  • In this report, we describe 12 cases of a distinctive gastric tumor, named here as plexiform fibromyxoma.
  • All tumors were located in the gastric antrum and 6 of them also extended into extragastric soft tissues or into the duodenal bulb.
  • The tumor cells varied from oval to spindled and had limited atypia and mitotic activity < 5/50 high-power fields.
  • Immunohistochemically, the tumor cells were positive for alpha smooth muscle actin, and variably for CD10, and were consistently negative for KIT, DOG1, CD34, desmin, and S100 protein.
  • Additional 3 patients survived 14 to 25 years with unknown tumor status.
  • Plexiform fibromyxoma is a distinctive benign gastric antral neoplasm that should be separated from GIST, nerve sheath tumors, and other fibromyxoid neoplasms.
  • [MeSH-major] Fibroma / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. Pyloric Antrum / pathology. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Child. Diagnosis, Differential. Disease-Free Survival. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Invasiveness. Young Adult

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  • (PMID = 19675452.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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93. Dhingra KK, Mandal S, Roy S, Khurana N: Malignant peripheral nerve sheath tumor of the breast: case report. World J Surg Oncol; 2007;5:142
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  • [Title] Malignant peripheral nerve sheath tumor of the breast: case report.
  • BACKGROUND: Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma of ectomesenchymal origin.
  • It is the malignant counterpart of benign soft tissue tumors like neurofibromas and schwannomas and may often follow them.
  • Common sites include deeper soft tissues, usually in the proximity of a nerve trunk.
  • Breast is an extremely rare location of this lesion and presentation as a breast lump in the absence of pain or previous benign neural tumor is even rarer.
  • Histopathology revealed a malignant spindle cell tumor which was confirmed to be malignant peripheral nerve sheath tumor on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.
  • The differential diagnosis of malignant peripheral nerve sheath tumor should be considered by the clinician as well as the pathologists in the work-up of a breast neoplasm as treatment and prognosis of this rare malignancy is different.
  • [MeSH-major] Breast Neoplasms / pathology. Nerve Sheath Neoplasms / pathology. Peripheral Nervous System Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Vimentin / metabolism

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  • [Cites] Orv Hetil. 1998 Jan 18;139(3):137-9 [9467297.001]
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  • (PMID = 18154670.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
  • [Other-IDs] NLM/ PMC2246134
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94. Ucak A, Inan K, Onan B, Yilmaz AT: Resection of intrapericardial hibernoma associated with constrictive pericarditis. Interact Cardiovasc Thorac Surg; 2009 Oct;9(4):717-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hibernoma is a benign soft-tissue tumor, which arises from the remnants of fetal brown adipose tissue.
  • When the tumor increases in size, this benign pathology can lead to compression of cardiac chambers and cause life-threatening complications in an asymptomatic patient.
  • The tumor was excised and diagnosed as hibernoma.

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  • (PMID = 19596706.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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95. Varras M, Akrivis Ch, Tsoukalos G, Plis Ch, Karadaglis S, Ladopoulos I: Tubal ectopic pregnancy associated with an extraskeletal chondroma of the fallopian tube: case report. Clin Exp Obstet Gynecol; 2008;35(1):83-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extraskeletal chondroma is a relatively uncommon benign soft tissue tumor, which usually occurs in the hands and feet.
  • The tumor may also occur around the tendon, synovium, or joint capsule.
  • [MeSH-major] Chondroma / complications. Fallopian Tube Neoplasms / complications. Pregnancy, Tubal / etiology

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  • (PMID = 18390091.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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96. Canavese F, Soo BC, Chia SK, Krajbich JI: Surgical outcome in patients treated for hemangioma during infancy, childhood, and adolescence: a retrospective review of 44 consecutive patients. J Pediatr Orthop; 2008 Apr-May;28(3):381-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Hemangiomas are the most common tumors in infancy and childhood and account for 7% of benign soft tissue tumors.
  • Diagnosis is usually made in infancy or childhood.
  • There are only a few reports on the surgical treatment of these lesions, likely because the lesions are quite vascular, have a tendency to infiltrate into the muscle and other tissues, and the recurrence rate is quite high.
  • Asymptomatic lesions should be monitored to confirm the diagnosis and to look for signs of progression.
  • A marginal resection may be used to treat most superficial soft tissue tumors.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Child. Child, Preschool. Female. Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Treatment Outcome

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  • (PMID = 18362808.001).
  • [ISSN] 0271-6798
  • [Journal-full-title] Journal of pediatric orthopedics
  • [ISO-abbreviation] J Pediatr Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Koksel O, Demir Apaydin F, Ayan E, Demir M, Ozdulger A: Elastofibroma dorsi: Review of eight cases. Surg Today; 2010 May;40(5):423-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Elastofibroma dorsi (ED) is a rare, benign soft tissue tumor arising from connective tissue and usually found in the subscapular region.
  • We conducted this retrospective study to contribute to a better understanding of this tumor, the pathogenesis of which is still unclear.
  • The tumor was located on the right in two patients, on the left in one, and bilaterally in five.
  • CONCLUSIONS: We could not establish a relationship between the side of the dominant hand and the tumor location.
  • If this tumor becomes symptomatic, local excision is the best treatment; however, as malignant transformation has not been reported, follow-up is recommended for asymptomatic lesions.
  • [MeSH-major] Fibroma / surgery. Soft Tissue Neoplasms / surgery. Thoracic Neoplasms / surgery

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  • (PMID = 20425544.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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98. Azevedo-Pereira AE, Rigueiro MP, Abrão FC: Bronchial glomus tumor with right upper lobe atelectasis. J Bras Pneumol; 2010 May-Jun;36(3):390-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bronchial glomus tumor with right upper lobe atelectasis.
  • Glomus tumors are uncommon benign soft tissue neoplasms.
  • We report the case of a 32-year-old male who presented with right upper lobe atelectasis due to an endobronchial tumor.
  • The pathological diagnosis was bronchial glomus tumor.
  • Glomus tumor should be considered in the differential diagnosis of endobronchial lesions causing lobar atelectasis.
  • [MeSH-major] Bronchial Neoplasms / complications. Glomus Tumor / complications. Pulmonary Atelectasis / etiology
  • [MeSH-minor] Adult. Bronchial Diseases / diagnosis. Diagnosis, Differential. Humans. Male

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  • (PMID = 20625678.001).
  • [ISSN] 1806-3756
  • [Journal-full-title] Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • [ISO-abbreviation] J Bras Pneumol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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99. Dias PF, Pedro Rde L, Janine ME, Maia LC: Congenital epulis: an unusual case of spontaneous regression. Gen Dent; 2008 Jul-Aug;56(5):e25-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Congenital epulis is a rare benign neoplasm of the soft tissues.
  • [MeSH-major] Gingival Neoplasms / congenital. Neoplasm Regression, Spontaneous / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Follow-Up Studies. Humans. Infant

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  • (PMID = 21444268.001).
  • [ISSN] 0363-6771
  • [Journal-full-title] General dentistry
  • [ISO-abbreviation] Gen Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Kloboves-Prevodnik VV, Us-Krasovec M, Gale N, Lamovec J: Cytological features of lipoblastoma: a report of three cases. Diagn Cytopathol; 2005 Sep;33(3):195-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma is a rare benign neoplasm occurring mostly in children under the age of three.
  • Accurate preoperative diagnosis is mandatory for planning the treatment.
  • The main aim of this study is to establish the cytological features of lipoblastoma and to answer the question: "Is cytological diagnosis of lipoblastoma reliable?
  • "Preoperative fine-needle aspiration biopsy (FNAB) and tissue sections of three children treated for lipoblastoma at the Division of Pediatrics, University Medical Center, Ljubljana, Slovenia, in the period from 1997 to 2004 were reexamined.
  • The tumor cells were in clusters and tissue fragments or as single cells.
  • Thin branching capillaries were observed in most of the clusters and tissue fragments.
  • In the first case, the cytological diagnosis was benign soft-tissue tumor, in the second the diagnosis was not conclusive and the last case was correctly diagnosed as lipoblastoma.
  • In the differential diagnosis of the second case, both lipoblastoma and liposarcoma were considered cytologically as well as histologically.
  • [MeSH-major] Lipoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Infant. Male

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16078242.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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