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Items 1 to 39 of about 39
1. Maheshwari R, Thool A: Orbital cavernous hemangioma of childhood. Indian J Ophthalmol; 2007 Jul-Aug;55(4):313-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital cavernous hemangioma of childhood.
  • Ocular and orbital tumors, both benign and malignant, occur relatively frequently in infants and children.
  • Benign masses are much more common than malignant in the orbital region.
  • However, childhood tumors show great variability and it is difficult to differentiate benign from malignant lesions.
  • Cavernous hemangioma is the most common benign neoplasm of the orbit in adults.
  • We report a case of orbital cavernous hemangioma in a four-year-old girl presenting as unilateral painless proptosis.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 17595488.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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2. Chanfi M: [Tuberous angioma in an infant: a case study]. J Fr Ophtalmol; 2005 Sep;28(7):774
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tuberous angioma of the orbit is the most frequent benign tumor of the orbit in children.
  • Angiomatous tumors in general, and more particularly tuberous angioma tumors, are classed among the primary tumors of the orbit.

  • Genetic Alliance. consumer health - Angioma.
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  • (PMID = 16208215.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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3. Zhou M, Xu G, Bojanowski CM, Song Y, Chen R, Sun X, Wang W, Chan CC: Differential diagnosis of anterior chamber cysts with ultrasound biomicroscopy: ciliary body medulloepithelioma. Acta Ophthalmol Scand; 2006 Feb;84(1):137-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential diagnosis of anterior chamber cysts with ultrasound biomicroscopy: ciliary body medulloepithelioma.
  • The patient was followed for 8 months without any metastasis in the orbit or elsewhere.
  • CONCLUSION: Intraocular medulloepithelioma is a rare embryonic benign or malignant neoplasm typically diagnosed in the first decade of life as a ciliary body mass.

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  • [Cites] Br J Ophthalmol. 1999 Mar;83(3):334-8 [10365043.001]
  • [Cites] Ophthalmology. 1996 Dec;103(12):1998-2006 [9003333.001]
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  • (PMID = 16445454.001).
  • [ISSN] 1395-3907
  • [Journal-full-title] Acta ophthalmologica Scandinavica
  • [ISO-abbreviation] Acta Ophthalmol Scand
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / / Z01 EY000222-22
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Other-IDs] NLM/ NIHMS54981; NLM/ PMC2441603
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4. Burduk PK, Seredyka-Burduk M, Olejarz E: [Giant tumor of the orbit--a case of hidradenoma]. Otolaryngol Pol; 2007;61(6):1017-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant tumor of the orbit--a case of hidradenoma].
  • Orbital tumors are very differential group of lesions.
  • More often a benign lesions is found than malignant.
  • We present a case of 62 years old man with large expansion of benign tumor of the orbit with exophthalmus, eye movement disability and complete blindness.
  • The authors performed radical surgery with removing of the orbit content.
  • Histopathology described a very rare tumor of the orbit-hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Orbital Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 18546956.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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5. Ray B, Bandyopadhyay SN, Das D, Adhikary B: A rare cause of nasolacrimal duct obstruction: dentigerous cyst in the maxillary sinus. Indian J Ophthalmol; 2009 Nov-Dec;57(6):465-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The secondary acquired obstructions may result from infection, inflammation, neoplasm, trauma or mechanical causes.
  • These cysts are benign odontogenic cysts which are associated with the crowns of unerupted teeth.
  • [MeSH-minor] Child. Dacryocystorhinostomy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Otorhinolaryngologic Surgical Procedures / methods. Tomography, X-Ray Computed

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  • [Cites] Orbit. 2003 Dec;22(4):289-92 [14685904.001]
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  • (PMID = 19861752.001).
  • [ISSN] 1998-3689
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2812769
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6. Coutinho-Camillo CM, Brentani MM, Nagai MA: Genetic alterations in juvenile nasopharyngeal angiofibromas. Head Neck; 2008 Mar;30(3):390-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm of the nasopharynx that accounts for 0.5% of all head and neck tumors.
  • Although histologically benign in appearance, JNAs are locally aggressive and destructive, spreading from the nasal cavity to the nasopharynx, paranasal sinuses, and orbit skull base with intracranial extension.
  • The gender selectivity of JNA and the relatively young age at diagnosis suggest hormone-dependent development.
  • Hormonal disorders have been reported in patients with JNA, and androgen and estrogen receptors have been identified in tumor tissue; however, a hormonal influence on JNA is controversial.
  • Understanding of the molecular mechanisms involved in JNA might improve prevention, prognosis, and treatment of this tumor.

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.
  • (PMID = 18228521.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Receptors, Steroid; 0 / beta Catenin; EC 2.5.1.18 / Glutathione Transferase
  • [Number-of-references] 103
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7. Dallaudiere B, Benayoun Y, Boncoeur-Martel M, Robert P, Adenis J, Maubon A: [Imaging features of cavernous hemangiomas of the orbit]. J Radiol; 2009 Sep;90(9 Pt 1):1039-45

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Imaging features of cavernous hemangiomas of the orbit].
  • Cavernous hemangioma is the most frequent benign tumor of the orbit.
  • The clinical presentation is that of a slowly progressive intra-orbital mass with variable degree of exophthalmos.
  • CT typically demonstrates the presence of a well defined oval or rounded shaped mass but MRI provides superior evaluation of the orbit.
  • The tumor is intra-conal in 80% of cases and usually shows T1W hypo-isointensity, T2W hyperintensity and heterogeneous contrast enhancement that becomes more homogeneous on delayed imaging (5 minutes).
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 19752807.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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8. Tam ES, Chen EC, Nijhawan N, Harvey JT, Howarth D, Oestreicher JH: Solitary fibrous tumor of the orbit: a case series. Orbit; 2008;27(6):426-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the orbit: a case series.
  • PURPOSE: Solitary fibrous tumor (SFT) occurs rarely in the orbit.
  • We present four such cases, representing one of the largest case series reported to date of this rare orbital tumor.
  • All four patients underwent CT scan to confirm the diagnosis of an orbital mass, which was then excised.
  • One of these cases demonstrated residual tumor on follow-up CT scan, which remained unchanged at one-year follow-up.
  • No evidence of residual tumor was found in the other three cases, despite one having malignant pathology.
  • CONCLUSION: SFT is a rare and generally benign tumor of the orbit.
  • Immunohistochemical testing with CD34 is necessary to confirm the diagnosis.
  • Although en bloc tumor resection is the definitive treatment, residual tumor may remain stable for some time.
  • [MeSH-major] Fibroma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Female. Humans. Male. Middle Aged. Neoplasm Proteins / analysis. Tomography, X-Ray Computed. Vimentin / analysis

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  • (PMID = 19085297.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Vimentin
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9. deSousa JL, Meligonis G, Malhotra R: Giant cell angiofibroma of the orbit with periosteal adherence. Clin Exp Ophthalmol; 2006 Dec;34(9):886-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cell angiofibroma of the orbit with periosteal adherence.
  • We report a case of orbital giant cell angiofibroma, an unusual, recently reported benign spindle cell neoplasm.
  • Preoperative clinical assessment and radiology suggested a benign mass and early operative findings were in concordance with this.
  • As with some lymphangiomas, this is another benign orbital tumour which may present difficulties in complete surgical excision that are not anticipated based on the preoperative findings.
  • [MeSH-major] Angiofibroma / diagnosis. Giant Cell Tumors / diagnosis. Orbital Neoplasms / diagnosis. Periosteum / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Ophthalmologic Surgical Procedures. Tissue Adhesions. Tomography, X-Ray Computed

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  • (PMID = 17181622.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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10. Scheckenbach K, Winterhalter S, Chaker A, Hoffmann TK, Ramp U, Wagenmann M: [MALT lymphoma of the orbit]. HNO; 2008 Feb;56(2):161-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MALT lymphoma of the orbit].
  • [Transliterated title] MALT-Lymphom der Orbita.
  • MALT lymphomas of the orbit are rare orbital tumors; the differential diagnosis needs to exclude inflammatory pseudotumors of the orbit, but also benign lymphoproliferations, pseudolymphomas, and other orbital neoplasms.
  • After histological confirmation of the diagnosis staging is necessary, and - as long as the disease is localized exclusively in the orbit - radiation therapy should be started.
  • The clinical picture of MALT lymphoma and its differential diagnosis and treatment are discussed with reference to an actual case.
  • [MeSH-major] Lymphoma, B-Cell, Marginal Zone / diagnosis. Orbital Neoplasms / diagnosis
  • [MeSH-minor] Aged. Antigens, CD20 / analysis. Antigens, CD3 / analysis. Biopsy. Chromosome Aberrations. Chromosome Deletion. Chromosomes, Human, Pair 11 / genetics. Diagnosis, Differential. Diplopia / etiology. Dose Fractionation. Endoscopy. Exophthalmos / etiology. Female. Follow-Up Studies. Humans. Ki-67 Antigen / analysis. Magnetic Resonance Imaging. Neoplasm Staging. Oculomotor Muscles / pathology. Orbit / pathology

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  • (PMID = 17143610.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD3; 0 / Ki-67 Antigen
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11. Jakobiec FA, Nguyen J, Bhat P, Fay A: MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):413-5
Genetic Alliance. consumer health - Liposarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit.
  • PURPOSE: To distinguish, in a 36-year-old man, an atypical lipomatous neoplasm/well-differentiated liposarcoma from a spindle cell lipoma in a recurrent orbital tumor.
  • RESULTS: MDM2 gene amplification was discovered in the CD34 tumor cells.
  • These findings established the diagnosis of a well-differentiated liposarcoma with lipoma-like and spindle cell features and ruled out a spindle cell lipoma.
  • CONCLUSION: Well-differentiated liposarcoma is a slow growing, infiltrative, and nonmetastasizing neoplasm that is microscopically and diagnostically challenging.
  • It can be reliably separated from a benign spindle cell or an atypical lipoma by using the markers MDM2 and Ki-67.
  • [MeSH-major] Biomarkers, Tumor / analysis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbital Neoplasms / diagnosis. Proto-Oncogene Proteins c-mdm2 / analysis

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  • (PMID = 20639786.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / S100 Proteins; 9013-56-3 / Factor XIII; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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12. Golub JS, Parikh SL, Budnick SD, Bernardino CR, DelGaudio JM: Inverted papilloma of the nasolacrimal system invading the orbit. Ophthal Plast Reconstr Surg; 2007 Mar-Apr;23(2):151-3
MedlinePlus Health Information. consumer health - Tears.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inverted papilloma of the nasolacrimal system invading the orbit.
  • This case illustrates the importance of including inverted papilloma, a benign but invasive neoplasm, in the differential diagnosis of nasolacrimal duct obstruction.
  • [MeSH-major] Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Nasolacrimal Duct / pathology. Orbital Neoplasms / pathology. Papilloma, Inverted / pathology
  • [MeSH-minor] Aged. Dacryocystorhinostomy. Humans. Male. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 17413635.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Krause E, Gürkov R, Klauss V: [Solitary fibrous tumor in the orbit. Case report and review of the literature]. HNO; 2009 Feb;57(2):169-72

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary fibrous tumor in the orbit. Case report and review of the literature].
  • [Transliterated title] Solitärer fibröser Tumor in der Orbita. Fallbericht und Literaturübersicht.
  • BACKGROUND: Solitary fibrous tumor (SFT) is a mesenchymal neoplasm with a benign growth behavior.
  • In the orbital cavity, SFT is rare.
  • Tumor growth over 7 years led to a severe exophthalmos with loss of vision.
  • CONCLUSION: SFT is a rare differential diagnosis of orbital lesions and can be appropriately treated by surgical resection.
  • [MeSH-major] Blindness / etiology. Blindness / prevention & control. Orbital Neoplasms / complications. Orbital Neoplasms / surgery. Solitary Fibrous Tumors / complications. Solitary Fibrous Tumors / surgery

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  • (PMID = 19221826.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 18
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14. Nagulić M, Nikolić I, Manojlović-Gacić E, Skender-Gazibara M: Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period. Vojnosanit Pregl; 2010 Jun;67(6):507-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period.
  • BACKGROUND: Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults.
  • Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare.
  • Tumor recurrence is supposed to develop from vasculature that is present already in response to a proliferate stimulus.
  • CASE REPORT: A 39-year-old female with painless proptosis of the right orbit was found to have four orbital tumors.
  • Six years later, another, the fifth one cavernous hemangioma was totally excised from the same orbit.
  • Nine years after the first operation, reorbitotomy was performed because of positive radiological and clinical signs of de novo tumor in the orbit.
  • CONCLUSION: This case show the possibility of cavernous hemangioma recurrence after a previously totally excised tumor, separated more than two decades.
  • A very long follow-up of the patients operated for these benign tumor lesions is recommended.
  • [MeSH-major] Hemangioma, Cavernous. Neoplasm Recurrence, Local. Neoplasms, Multiple Primary. Orbital Neoplasms

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  • (PMID = 20629431.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
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15. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • On radiologic examination, the mass was seen to extend into the anterior orbit.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.
  • It is important to consider it preoperatively because the vascular nature of this tumour may create problems with hemostasis during excision.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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16. Gündüz K, Catak E, Erden E: Optic nerve biopsy via a medial transconjunctival orbitotomy approach in the diagnosis of optic nerve and sheath tumors. Orbit; 2010 Aug;29(4):190-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optic nerve biopsy via a medial transconjunctival orbitotomy approach in the diagnosis of optic nerve and sheath tumors.
  • PURPOSE: To evaluate the role of optic nerve biopsy in the diagnosis and management of optic nerve and sheath tumors.
  • CONCLUSIONS: Many other benign and malignant optic nerve and sheath tumors have imaging features similar to those seen in JPA and ONSM.
  • Therefore, it is important to establish histopathologic diagnosis before embarking on treatment.
  • Furthermore, tissue diagnosis is required prior to EBRT in many institutions because of concerns about medicolegal liability.
  • [MeSH-minor] Adolescent. Astrocytoma / pathology. Astrocytoma / surgery. Child. Child, Preschool. Conjunctiva / surgery. Female. Follow-Up Studies. Humans. Male. Meningioma / pathology. Meningioma / surgery. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Ophthalmologic Surgical Procedures / methods. Orbit / surgery. Sampling Studies

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  • (PMID = 20812834.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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17. Asensio Sánchez VM, Alonso M, Sierra JM: [Positron emission tomography in the diagnosis of orbital relapse of choroidal melanoma]. Arch Soc Esp Oftalmol; 2005 Feb;80(2):113-5
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  • [Title] [Positron emission tomography in the diagnosis of orbital relapse of choroidal melanoma].
  • [Transliterated title] Tomografía por emisión de positrones en el diagnóstico de recidiva orbitaria de un melanoma de coroides.
  • Three years later MRI demonstrated images compatible with recurrent tumor in the orbit.
  • DISCUSSION: In patients after enucleation of choroidal melanoma, conventional imaging techniques can fail to establish differentiation between malignant from post-surgery and benign anatomic abnormalities in orbital tissue that can be detected by PET scanning.
  • [MeSH-major] Choroid Neoplasms / pathology. Melanoma / secondary. Neoplasm Recurrence, Local / diagnosis. Orbit / pathology. Orbital Neoplasms / secondary. Positron-Emission Tomography
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 15750891.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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18. Schmack I, Patel RM, Folpe AL, Wojno T, Zaldivar RA, Balzer B, Kang SJ, Weiss SW, Grossniklaus HE: Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. Am J Surg Pathol; 2007 Feb;31(2):193-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor.
  • Prolapse of subconjunctival intraconal orbital fat is a rare cause of an intraorbital mass lesion.
  • Over the past several years, we have seen a number of cases in which this prolapsed fat was confused pathologically with a neoplasm of adipocytic lineage, specifically pleomorphic lipoma and atypical lipomatous neoplasm (well-differentiated liposarcoma).
  • We report the clinical, histopathologic, and immunohistochemical findings in 21 specimens from 17 patients, all of whom presented with prolapsed intraconal orbital fat.
  • Subconjunctival prolapsed orbital fat was localized in the superotemporal quadrant or lateral canthus around the rectus muscle below the lacrimal gland.
  • "Control" sections of normal orbital fat showed occasional Lochkern cells but lacked floret cells.
  • We conclude that subconjunctival herniated orbital fat commonly contains multinucleated floretlike giant cells, fibrous septae, and Lochkern cells, features that may result in diagnostic confusion with pleomorphic lipoma and atypical lipomatous neoplasms.
  • Importantly, specific diagnostic features, such as aggregates of bland spindled cells associated with wiry collagen, as seen in pleomorphic lipoma, and enlarged hyperchromatic cells within fibrous septae, as in atypical lipomatous neoplasms, are entirely absent in herniated orbital fat.
  • Multinucleated floret cells present in prolapsed orbital fat likely represent a reactive phenomenon, as they are not present in normal orbital fat.
  • [MeSH-major] Adipose Tissue / pathology. Conjunctiva / pathology. Conjunctival Diseases / pathology. Eye Neoplasms / diagnosis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbit / pathology
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adult. Aged. Aged, 80 and over. Biomarkers / metabolism. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prolapse. Tomography, X-Ray Computed

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  • (PMID = 17255763.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30-EY06360
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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19. Lardinois D, Weder W, Roudas M, von Schulthess GK, Tutic M, Moch H, Stahel RA, Steinert HC: Etiology of solitary extrapulmonary positron emission tomography and computed tomography findings in patients with lung cancer. J Clin Oncol; 2005 Oct 1;23(28):6846-53
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  • A diagnosis was obtained in 69 of these patients, including 37 (54%) with solitary metastases and 32 (46%) with lesions unrelated to the lung primary.
  • Histopathologic examinations of these 32 lesions revealed a second clinically unsuspected malignancy or a recurrence of a previous diagnosed carcinoma in six patients (19%) and a benign tumor or inflammatory lesion in 26 patients (81%).
  • The six malignancies consisted of carcinoma of the breast in two patients, and carcinoma of the orbit, esophagus, prostate, and non-Hodgkin's lymphoma in one patient each.
  • Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture.
  • CONCLUSION: Solitary extrapulmonary FDG accumulations in patients with newly diagnosed lung cancer should be analyzed critically for correct staging and optimal therapy, given that up to half of the lesions may represent unrelated malignancies or benign disease.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Lung Neoplasms / radionuclide imaging. Neoplasm Metastasis / radionuclide imaging. Positron-Emission Tomography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Fluorodeoxyglucose F18. Humans. Inflammation. Male. Middle Aged. Neoplasm Staging. Prospective Studies. Radiopharmaceuticals. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 16192576.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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20. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They can occur in any part of the body including the orbital tissues.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • The rarity of the tumour makes its diagnosis and management a challenge.
  • Herein, the clinicopathological features of a case of malignant fibrous histiocytoma are presented and its management with wide excision and cryotherapy followed by ocular reconstruction with amniotic membrane transplant is discussed.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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21. Irace C, Davì G, Corona C, Candino M, Usai S, Gambacorta M: Isolated intraorbital schwannoma arising from the abducens nerve. Acta Neurochir (Wien); 2008 Nov;150(11):1209-10
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  • CASE REPORT: A case of isolated schwannoma of the orbit, arising from the terminal branches of the abducens nerve to the lateral rectus muscle, is reported.
  • DISCUSSION: Preoperative diagnosis of benign intraorbital neoplasm was made by means of CT and MR scans; the mass was radically excised through a microsurgical lateral orbitotomy and the pathological examination revealed a schwannoma.
  • Features of orbital schwannoma are described, together with some details concerning the surgical strategy and the history of the evolution of the lateral orbitotomy.
  • [MeSH-major] Abducens Nerve / pathology. Abducens Nerve Diseases / pathology. Cranial Nerve Neoplasms / pathology. Neurilemmoma / pathology. Orbit / pathology

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  • (PMID = 18941708.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers; 0 / S100 Proteins
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22. George JL, Marchal JC: [Orbital tumors in children: clinical examination, imaging, specific progression]. Neurochirurgie; 2010 Apr-Jun;56(2-3):244-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Orbital tumors in children: clinical examination, imaging, specific progression].
  • [Transliterated title] Les tumeurs d'orbite de l'enfant : examen clinique, paraclinique, diagnostic et particularités évolutives.
  • "Orbital tumors (OT) are neoplasms of the bony orbit and contents except for the eyeball."
  • Examination must be careful: measurement, direction of proptosis, impairment of ocular motility, compressive optic neuropathy, strabismus, etc.
  • Benign tumors such as dermoid cysts or hemangiomas grow slowly, whereas rapid growth suggests a malignant tumor.
  • When a metastatic tumor is suspected, abdominal palpation and ultrasonography must be performed.
  • Ultrasonography leaves the posterior third of the orbit inaccessible to exploration.
  • The depth to which it can penetrate the orbit is limited (20mm).
  • Most of the time, standard x-rays, CT, and MR imaging allow for an adequate assessment and usually provide a diagnosis.
  • [MeSH-major] Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adult. Age Factors. Child. Disease Progression. Emotions. Exophthalmos / etiology. Humans. Leukemia / diagnosis. Leukemia / epidemiology. Leukemia / pathology. Neoplasm Metastasis / pathology. Neuroblastoma / diagnosis. Neuroblastoma / epidemiology. Neuroblastoma / pathology. Palpation. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / epidemiology. Rhabdomyosarcoma / pathology

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20303555.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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23. Rodríguez-Velasco A, Fermán-Cano F, Cerecedo-Díaz F: Rare tumor of the tongue in a child: alveolar soft part sarcoma. Pediatr Dev Pathol; 2009 Mar-Apr;12(2):147-51
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  • [Title] Rare tumor of the tongue in a child: alveolar soft part sarcoma.
  • Alveolar soft part sarcoma (ASPS) is a rare, malignant tumor of uncertain histogenesis that has no benign counterpart.
  • The neoplasm occurs most frequently in female adolescents and young adults, where it arises predominantly in the extremities.
  • In contrast, the most common sites of occurrence in infants and children are the orbit (41%) and the tongue (25%).
  • Because of the indolent growth and lack of pain associated with the mass, 20% of patients have metastases at the time of initial diagnosis.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Child, Preschool. Cyclophosphamide / therapeutic use. Dactinomycin / therapeutic use. Disease-Free Survival. Female. Humans. Vimentin / analysis. Vincristine / therapeutic use

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  • (PMID = 18630993.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin; 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; VAC protocol
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24. Giudice C, Marco R, Mirko R, Luca M, Giorgio C: Zygomatic gland adenoma in a dog: histochemical and immunohistochemical evaluation. Vet Ophthalmol; 2005 Jan-Feb;8(1):13-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Orbital epithelial tumors in dogs are rare and most frequently malignant.
  • Distinguishing their origin from the lacrimal or zygomatic gland is often challenging and is based mostly on tumor location.
  • A case of adenoma involving the orbit in a 13-year-old, female, standard Schnauzer is reported.
  • Histologically, the neoplasm was characterized by nests and cords of epithelial cells mostly forming small glandular structures.
  • The origin of the tumor from the zygomatic gland was determined by histochemical characteristics (alcian blue pH 1 positive staining) of a small remnant of normal gland included within the tumor capsule.
  • The benign nature of our finding was confirmed by follow-up information: 2 years after complete surgical removal of the mass no tumor recurrence or metastases was recorded.
  • [MeSH-major] Adenoma / veterinary. Dog Diseases / diagnosis. Lacrimal Apparatus. Orbital Neoplasms / veterinary
  • [MeSH-minor] Animals. Diagnosis, Differential. Dogs. Female. Immunohistochemistry / veterinary

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  • (PMID = 15644095.001).
  • [ISSN] 1463-5216
  • [Journal-full-title] Veterinary ophthalmology
  • [ISO-abbreviation] Vet Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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25. Durden FL Jr, Moore CE, Muller S: Verrucous carcinoma of the paranasal sinuses: a case report. Ear Nose Throat J; 2010 Jul;89(7):E21-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor grows locally invasive but is histologically benign and metastasizes rarely.
  • We present a case of verrucous carcinoma involving the paranasal sinuses, nasal cavity, cranium, and orbit.
  • This case highlights the difficulty of pathologic diagnosis and management options for a rare neoplastic lesion.
  • [MeSH-minor] Biopsy. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiation effects. Nasal Cavity / surgery. Neoplasm Invasiveness. Neoplasm Staging. Orbital Neoplasms / pathology. Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Skull / pathology. Skull / radiation effects. Skull / surgery. Skull Neoplasms / pathology. Skull Neoplasms / radiotherapy. Skull Neoplasms / surgery

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  • (PMID = 20628974.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Segal A, Segal N, Gal A, Tumuluri K: Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor. Orbit; 2010 Dec;29(6):334-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor.
  • In 12(21.8%) patients a lesion with a benign diagnosis was previously excised from the same location.
  • In 2 of them histological re-examination resulted in a diagnosis of MSA.
  • Recurrence of the tumor was reported in 14(30%) patients.
  • CONCLUSIONS: MSA is a rare tumor of the eyelid with no clinically distinguishing features.
  • The tumor may extend into the orbit and metastasize regionally.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eyelid Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Mohs Surgery / methods. Neoplasm Staging. Rare Diseases. Risk Assessment. Treatment Outcome

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  • (PMID = 21158574.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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27. Kaur A, Agrawal A, Agrawal PK, Goel MM: Lacrimal canalicular obstruction by cysticercus cellulosae. Orbit; 2006 Jun;25(2):163-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ocular adnexal infestation in cysticercosis is unusual.
  • The diagnosis was established by histopathological examination of the cyst, surgically removed from the above patient with a suspected benign neoplasm in the lacrimal passage.

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  • (PMID = 16754231.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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28. Wilde F, Neid M, Schulz T, Sterker I, Hemprich A, Frerich B: [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases]. Mund Kiefer Gesichtschir; 2005 Nov;9(6):404-8
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  • [Title] [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases].
  • [Transliterated title] Hämangioperizytom (extrapleuraler solitärer fibröser Tumor). Dargestellt und diskutiert anhand zweier Patientenbeispiele.
  • It is a very uncommon potentially malignant vascular tumour which can occur at every site of the body.
  • The diagnosis of "hemangiopericytoma" is now only determined if a constant histological picture of hemangiopericytoma is present.
  • The tumour can lead to lymphogenous or hematogenous metastasis.
  • CASE REPORTS: Patient 1: 60 years, female; diagnosis: malignant suboccipital hemangiopericytoma; size: 4.9 x 4.5 x 4.2 cm; pT1bNXMX L0 V0 Pn0; stage IA; grading G1; R0.Patient 2: 38 years, male; diagnosis: benign hemangiopericytoma infraorbital left; size 1.5 x 1.5 x 1.5 cm.
  • The slow and painless growth carries the danger of a clinically wrong diagnosis and thus delayed therapy.
  • The histological diagnosis of hemangiopericytoma is determined by biopsy.
  • The therapy of choice is the complete tumour-resection with a safety margin of 1 cm.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangiopericytoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Orbit / pathology. Orbital Neoplasms / diagnosis. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 16220316.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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29. Kashkouli MB, Khalatbari MR, Yahyavi T, Borghei Razavi H, Shayanfar N, Parvaresh MM: Primary endo-orbital osteoid osteoma. Orbit; 2008;27(3):211-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary endo-orbital osteoid osteoma.
  • Osteiod osteoma is a small, benign, osteoblastic tumor, which usually affects the long bone of the lower extremities and vertebrae.
  • Herein, we report the first case of endo-orbital osteoid osteoma.
  • Imaging studies showed a small (15 x 11 mm in size) lesion on the roof of the left orbit with contrast enhancement.
  • [MeSH-major] Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Osteoma, Osteoid / pathology. Osteoma, Osteoid / surgery
  • [MeSH-minor] Adult. Biopsy, Needle. Exophthalmos / diagnosis. Exophthalmos / etiology. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18569832.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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30. Maroldi R, Ravanelli M, Borghesi A, Farina D: Paranasal sinus imaging. Eur J Radiol; 2008 Jun;66(3):372-86
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  • Endonasal surgery is currently extending its application beyond inflammatory sinonasal lesions to successfully treat both benign and malignant neoplasms.
  • CT provides excellent details about the thin bony sinonasal walls separating the ethmoid from the anterior skull base and the orbit.
  • Benign and malignant neoplasms are the "domain" of MRI because the tumor is more easily separated from adjacent structures, the periosteal linings (periorbita, dura mater) and perineural spread can be accurately shown.
  • Whereas MRI precisely assess pre-treatment tumor extent, early submucosal local recurrences are difficult to demonstrate because of post-treatment changes of the anatomy and of the signal of treated tissues.
  • [MeSH-major] Diagnostic Imaging. Paranasal Sinus Diseases / diagnosis
  • [MeSH-minor] Contrast Media. Humans. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 18375083.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 67
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31. Leoncini G, Maio V, Puccioni M, Franchi A, De Giorgi V, Ucci F, Santucci M, Massi D: Orbital solitary fibrous tumor: a case report and review of the literature. Pathol Oncol Res; 2008 Jun;14(2):213-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital solitary fibrous tumor: a case report and review of the literature.
  • Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm typically arising in the pleura and involving the orbit as its most common extra-pleural location.
  • We herein describe a well documented case of orbital SFT arising in a 62-year-old woman presenting with progressive swelling of the right upper eyelid and proptosis.
  • The tumor had a benign clinical course, with radical surgical excision followed by regression of the clinical symptoms.
  • We review the clinical, histopathological, and immunohistochemical features of the orbital SFT described so far, with particular emphasis on differential diagnosis with other spindle cell orbital neoplasms.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / surgery. Solitary Fibrous Tumors / diagnosis. Solitary Fibrous Tumors / surgery
  • [MeSH-minor] Diagnosis, Differential. Exophthalmos / etiology. Female. Humans. Immunohistochemistry. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18493869.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 26
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32. Livaoĝlu M, Cakir E, Karaçal N: Large orbital osteoma arising from orbital roof: Excision through an upper blepharoplasty incision. Orbit; 2009;28(2-3):200-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large orbital osteoma arising from orbital roof: Excision through an upper blepharoplasty incision.
  • Osteoma is the most common benign tumor of facial bony structure.
  • We report a case of intraorbital, pedicled osteoma originating from the left orbital roof.
  • There were not any postoperative complications and all ocular symptoms in the left eye were resolved after 1 month.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / surgery. Osteoma / diagnosis. Osteoma / surgery
  • [MeSH-minor] Biopsy, Needle. Blepharoplasty / methods. Blepharoptosis / diagnosis. Blepharoptosis / etiology. Follow-Up Studies. Humans. Imaging, Three-Dimensional. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Ophthalmologic Surgical Procedures / methods. Risk Assessment. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19839914.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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33. Meli GA, Meli L, Chiaramonte R, Riva G, Pero G: Osteoblastoma of the orbit. A case report and review of the literature. Neuroradiol J; 2008 Feb 18;21(1):71-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteoblastoma of the orbit. A case report and review of the literature.
  • We describe a case of benign orbital tumour involving the frontal sinus and ethmoidal cells.
  • CT findings were typical of "bone tumour of the orbit", histological analysis yielded a diagnosis of benign osteoblastoma.
  • The orbit is rarely involved by bone tumours, but all bone tumours may theoretically involve the orbit, often making it difficult to establish the right differential diagnosis by imaging.
  • Even though many literature reports suggest CT is the landmark in bone tumour diagnosis, we think it should always be accompanied by MRI.
  • MRI is known to overestimate local staging, but its contribution to differential diagnosis among various tumours may be decisive.

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  • (PMID = 24256752.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Wakefield MJ, Ross AH, Damato EM, Salvi SM, Baker GR: Review of lateral orbital wall ossifying fibroma. Orbit; 2010 Dec;29(6):317-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Review of lateral orbital wall ossifying fibroma.
  • Significant histological overlap exists between fibro-osseous lesions and diagnosis is made on a clinicopathological basis.
  • Ossifying fibroma is a benign fibro-osseous neoplasm of the jaw and craniofacial complex that has generated a degree of controversy regarding diagnosis and classification, especially with respect to the psammomatoid variant.
  • Orbital lesions mainly arise from the paranasal sinuses affecting the medial or inferior orbital wall.
  • Lateral orbital wall ossifying fibroma is, therefore, a rare condition with only a single previous case report.
  • We present a second case of lateral orbital wall ossifying fibroma and a review of the associated literature.
  • [MeSH-major] Fibroma, Ossifying / pathology. Fibroma, Ossifying / radiography. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography

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  • (PMID = 21158572.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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35. Lindegaard J, Heegaard S, Toft PB, Nysom K, Prause JU: Malignant transformation of a medulloepithelioma of the optic nerve. Orbit; 2010 Jun;29(3):161-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A 3-year-old boy presented with right-sided proptosis, swollen eyelids, restricted ocular movements, pain and nausea.
  • A benign non-teratoid medulloepithelioma of the optic nerve was surgically removed.
  • Due to relapse in the orbit 10 months postoperatively enucleation and partial orbital exenteration were performed.
  • This is the first case described of a benign medulloepithelioma of the optic nerve, later transforming into a malignant tumour.
  • Furthermore; it should be considered as a differential diagnosis when observing a tumour of the optic nerve in a child.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Neoplasm Recurrence, Local / pathology. Neuroectodermal Tumors, Primitive / pathology. Optic Nerve Neoplasms / pathology
  • [MeSH-minor] Biopsy, Needle. Chemotherapy, Adjuvant. Child, Preschool. Exophthalmos / diagnosis. Exophthalmos / etiology. Eye Enucleation / methods. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging / methods. Male. Orbit Evisceration / methods. Radiotherapy, Adjuvant. Risk Assessment. Stem Cell Transplantation. Treatment Outcome

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  • (PMID = 20497085.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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36. Wang HY, Fan QH, Gong QX, Wang Z: [Clinicopathologic characteristics of hemangiopericytoma/solitary fibrous tumor with giant cells]. Zhonghua Bing Li Xue Za Zhi; 2009 Mar;38(3):169-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic characteristics of hemangiopericytoma/solitary fibrous tumor with giant cells].
  • OBJECTIVE: To study the pathological characteristics, diagnosis and differential diagnoses of hemangiopericytoma-solitary fibrous tumor with giant cells.
  • METHODS: Pathological characteristics of seven cases of orbital and extraorbital hemangiopericytoma-solitary fibrous tumors with giant cells were evaluated by HE and immunohistochemistry (EnVision method).
  • RESULTS: Two cases were located in the orbit, one of which had recurred.
  • Seven patients underwent tumor excision and were well and without tumor recurrence upon the clinical follow-up.
  • CONCLUSIONS: Hemangiopericytoma-solitary fibrous tumor with giant cells is an intermediate soft tissue tumor.
  • It typically involves the orbital or extraorbital regions.
  • Histologically, the tumor should be distinguished from giant cell fibroblastoma, pleomorphic hyalinzing angiectatic tumor of soft part and angiomatoid fibrous histiocytoma.
  • [MeSH-major] Hemangiopericytoma / pathology. Orbital Neoplasms / pathology. Solitary Fibrous Tumors / pathology
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Antigens, CD34 / metabolism. Cell Adhesion Molecules / metabolism. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Female. Follow-Up Studies. Histiocytoma, Benign Fibrous / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local. Proto-Oncogene Proteins c-bcl-2 / metabolism. Soft Tissue Neoplasms / pathology. Solitary Fibrous Tumor, Pleural / metabolism. Solitary Fibrous Tumor, Pleural / pathology. Solitary Fibrous Tumor, Pleural / surgery. Young Adult

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  • (PMID = 19575851.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Proto-Oncogene Proteins c-bcl-2
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37. Bajaj MS, Pushker N, Kashyap S, Sen S, Vengayil S, Chaturvedi A: Fibrous histiocytoma of the lacrimal gland. Ophthal Plast Reconstr Surg; 2007 Mar-Apr;23(2):145-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fibrous histiocytoma, a primary mesenchymal tumor of the orbit, is known to arise from various ocular and adnexal tissues.
  • We are unable to find a published report of this tumor originating from the lacrimal gland.
  • We report a case of a benign fibrous histiocytoma of the lacrimal gland in an 11 year old girl who presented with painless, progressive eyelid swelling and mild proptosis.
  • The tumor was completely excised by anterolateral orbitotomy.
  • Light microscopy showed a spindle cell tumor arising from the lacrimal gland.
  • The tumor cells were arranged in a characteristic storiform (cartwheel) pattern with no pleomorphism or mitotic figures.
  • Immunohistochemically, the tumor cells were focally positive for CD-68 and negative for S-100, smooth muscle actin, vimentin, and CD-34, which ruled out neurofibroma, leiomyoma, solitary fibrous tumor, and hemangiopericytoma.
  • Based on these features, a diagnosis of benign fibrous histiocytoma was made.
  • [MeSH-major] Eye Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Lacrimal Apparatus Diseases / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Child. Female. Humans. Neoplasm Proteins / analysis. Tomography, X-Ray Computed

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  • (PMID = 17413632.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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38. Subramanian N, Rambhatia S, Mahesh L, Menon SV, Krishnakumar S, Biswas J, Noronha OV: Cystic schwannoma of the orbit-a case series. Orbit; 2005 Jun;24(2):125-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic schwannoma of the orbit-a case series.
  • A schwannoma is an uncommon benign orbital tumor that arises from Schwann cells in the peripheral nervous system.
  • Clinical examination alone is inadequate for the diagnosis.
  • Radiological examination, like computed tomography (CT) scans, can help in the diagnosis; however, the diagnosis can only be confirmed by histopathological examination (HPE) after excision biopsy.
  • Here, the authors report four cases of orbital schwannoma with cystic degeneration that presented with proptosis and decreased vision.
  • The histopathological examination was diagnostic for orbital schwannoma with cystic degeneration.
  • Schwannoma should be included in the differential diagnosis of cystic orbital lesions.
  • [MeSH-major] Blepharoptosis / etiology. Neurilemmoma / pathology. Orbital Neoplasms / pathology. Vision Disorders / etiology

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  • (PMID = 16191802.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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39. Kumar S, Kumar S, Kulshrestha R: Cystic schwannoma of eyelid in an Indian male: a rare presentation. Orbit; 2008;27(6):407-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eyelid schwannoma (neurilemmomas) is an extremely rare, benign neoplasm.
  • Histopathological diagnosis of cystic schwannoma was made.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 19085294.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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