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1. Mandal RV, Duncan LM, Austen WG Jr, Nielsen GP: Infiltrating intramuscular spindle cell lipoma of the face. J Cutan Pathol; 2009 Oct;36 Suppl 1:70-3
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  • Spindle cell lipoma is a benign lipomatous tumor, which usually arises on the back of the neck, shoulder or upper back of males in the third to seventh decade of life.
  • We report herein an unusual infiltrating intramuscular spindle cell lipoma arising in the nose of a 53-year-old man.
  • The patient presented with a 0.5-cm 'cyst' of the nose, just above the right alar crease, which was removed.
  • [MeSH-major] Lipoma / pathology. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19187113.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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2. Jack LS, Smith TL, Ng JD: Frontal sinus osteoma presenting with orbital emphysema. Ophthal Plast Reconstr Surg; 2009 Mar-Apr;25(2):155-7
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  • Osteoma is the most common neoplasm of the paranasal sinuses usually involving the frontal sinus.
  • Osteomas are benign, but can cause serious intracranial or orbital complications.
  • The authors report a frontal sinus osteoma with orbital emphysema in a 16-year-old boy with a history of right-eye swelling after nose blowing.
  • The osteoma facilitated entrance of sinus air in the orbit, resulting in recurrent orbital emphysema with nose blowing.

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  • (PMID = 19300171.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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3. Ceylan A, Celenk F, Poyraz A, Uslu S: Pleomorphic adenoma of the nasal columella. Pathol Res Pract; 2008;204(4):273-6
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  • [Title] Pleomorphic adenoma of the nasal columella.
  • Pleomorphic adenoma (mixed tumor) is the most common benign neoplasm of the salivary glands.
  • An external nose localization of this lesion is very rare.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasm Recurrence, Local. Neoplasm Seeding. Nose Neoplasms / pathology

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  • (PMID = 18295980.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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4. Orhan KS, Karaaltın MV, Demirel T, Polat B, Başaran B: Adenolipoma of the nose: a case report. Kulak Burun Bogaz Ihtis Derg; 2010 Sep-Oct;20(5):264-6
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  • [Title] Adenolipoma of the nose: a case report.
  • Adenolipoma is a rare benign neoplasm composed of both mature adipose tissue and glandular elements.
  • In this article we report a case of 19-year-old woman, who had nasal blockage and deformity.
  • On examination, a round, soft, nonpulsatile submucosal mass in the cartilagenous vault of the right nasal cavity was found.
  • Computed tomography revealed a clearly demarcated dense mass located at the right submucopericondrial level obstructing the nasal passage.
  • To our knowledge, this is the first case report of an adenolipoma of the nose in the English literature.
  • [MeSH-major] Adenoma / surgery. Lipoma / surgery. Nose Neoplasms / surgery

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  • (PMID = 20815806.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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5. Cansiz H, Güvenç MG, Sekercioğlu N: Surgical approaches to juvenile nasopharyngeal angiofibroma. J Craniomaxillofac Surg; 2006 Jan;34(1):3-8
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  • These lesions are benign histologically but they may become life-threatening with excessive bleeding or intracranial extension.
  • The complications encountered in the postoperative course include temporary facial palsy in one patient (following a Fisch C infratemporal resection), mild crusting in the nasal cavity in 8 patients, and facial paraesthesia in 6 patients whose tumours were resected via midfacial degloving, and rupture of the subpetrous part of the internal carotid artery in one patient.
  • [MeSH-minor] Adolescent. Adult. Carotid Artery Injuries / etiology. Carotid Artery, Internal / pathology. Child. Craniotomy / adverse effects. Endoscopy. Facial Paralysis / etiology. Frontal Bone / surgery. Humans. Male. Neoplasm Staging. Nose / surgery. Nose Diseases / etiology. Paresthesia / etiology. Postoperative Complications. Retrospective Studies. Rupture. Temporal Bone / surgery. Treatment Outcome

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  • (PMID = 16343920.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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6. Charous DD, Cunnane MF, Rosen MR, Keane WM: Recurrent polymorphous low-grade adenocarcinoma manifesting as a sinonasal mass: a case report. Ear Nose Throat J; 2005 Jun;84(6):354, 356-7
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  • Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm that tends to follow a benign clinical course.
  • We report a case of recurrent PLGA of the paranasal sinuses that manifested as a large mass that filled the entire nasal cavity and left maxillary sinus.

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  • (PMID = 16075858.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Livaoğlu M, Karacal N, Bektaş D, Bahadir O: Reconstruction of full-thickness nasal defect by free anterolateral thigh flap. Acta Otolaryngol; 2009 May;129(5):541-4
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  • [Title] Reconstruction of full-thickness nasal defect by free anterolateral thigh flap.
  • CONCLUSION: Because of minimal donor region morbidity, pliability, the presence of long and large caliber vessels, and lack of visible scar, the free anterolateral thigh flap provides an ideal option for restoration of full-thickness nasal defects.
  • OBJECTIVE: Full-thickness nasal defect reconstruction requires internal nasal lining and external cover.
  • In large defects, internal nasal lining replacement with traditional sources may not be expedient.
  • We describe reconstruction of full-thickness nasal defects with free anterolateral thigh flap.
  • PATIENTS AND METHODS: From August 2005 to July 2007, six patients with full-thickness nasal defects underwent nasal reconstruction using free anterolateral thigh flap.
  • [MeSH-major] Nose / surgery. Nose Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Female. Histiocytoma, Benign Fibrous / surgery. Humans. Length of Stay. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Thigh / surgery

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  • (PMID = 18607893.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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8. Nakaya K, Oshima T, Watanabe M, Hidaka H, Kikuchi T, Higashi K, Honkura Y, Hara Y, Kobayashi T: A case of myoepithelioma of the nasal cavity. Auris Nasus Larynx; 2010 Oct;37(5):640-3
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  • [Title] A case of myoepithelioma of the nasal cavity.
  • Case reports of extra-salivary myoepithelioma are sporadic, with only one case in the nasal cavity.
  • A 68-year-old male patient presented with a myoepithelioma of the nasal cavity manifesting as nasal obstruction and epistaxis, which was treated successfully with endoscopic excision.
  • The behavioral pattern is similar to if not identical with that of the mixed tumor, pleomorphic adenoma, which is benign, but the potential for recurrence is always present, especially if complete resection is not achieved.
  • [MeSH-major] Myoepithelioma / diagnosis. Nasal Cavity. Nose Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biopsy. Humans. Magnetic Resonance Imaging. Male. Maxillary Sinus / pathology. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20392578.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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9. Nemec SF, Formanek M, Noebauer-Huhmann IM, Krestan CR, Frühwald J, Peloschek P, Herneth AM, Czerny C: [Pathological changes of the hypopharynx in the focus of imaging]. Radiologe; 2009 Jan;49(1):36-42
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  • [Transliterated title] Pathologische Veränderungen des Hypopharynx im Brennpunkt der Bildgebung.
  • The spectrum of pathological changes in anatomical sections of the hypopharynx ranges from benign pathologies to hypopharyngeal carcinoma.
  • Beside the clinical status and the endoscopic evaluation performed by ear, nose and throat specialists, imaging techniques play an important role in pre-therapeutic and post-therapeutic diagnostics and in the follow-up of pharyngeal disease patterns, especially for malignant lesions.
  • [MeSH-minor] Contrast Media / administration & dosage. Humans. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Tomography, Spiral Computed. Zenker Diverticulum / diagnosis. Zenker Diverticulum / pathology

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  • (PMID = 19023556.001).
  • [ISSN] 1432-2102
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 36
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10. Bignami M, Pistochini A, Meloni F, Delehaye E, Castelnuovo P: A rare case of oncocytic Schneiderian papilloma with intradural and intraorbital extension with notes of operative techniques. Rhinology; 2009 Sep;47(3):316-9
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  • Epithelial cells of cylindrical cell papilloma are oncocytes, which arise from the sinonasal respiratory epithelium, hence the term Oncocytic Schneiderian papilloma.This is a rare and benign neoplasm of the nose and paranasal sinuses and it should be considered in the work-up of all unilateral nasal polypoid lesions.
  • Surgical therapy is the treatment of choice, the endonasal endoscopic approach can be used in most of the cases and this surgical technique is safe and suitable also in presence of an extra nasal extension.
  • [MeSH-major] Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Oxyphil Cells / pathology. Papilloma / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Aged. Female. Humans. Magnetic Resonance Imaging. Nasal Mucosa / pathology

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  • (PMID = 19839258.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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11. Simon Cypel TK, Vijayasekaran V, Somers GR, Zuker RM: Pilomatricoma: experience of the hospital for sick children. Can J Plast Surg; 2007;15(3):159-61
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  • BACKGROUND: Pilomatricoma (calcifying epithelioma of Malherbe) is a common skin neoplasm in the pediatric population that is often misdiagnosed as other skin conditions or tumours.
  • OBJECTIVES: The objective of the present retrospective study was to review the clinical and histopathological presentation of this neoplasm in children.
  • CONCLUSIONS: This entity should be considered with other benign or malignant conditions in the clinical differential diagnosis of solitary firm skin nodules, especially those on the face, neck and upper limbs.

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  • (PMID = 19554149.001).
  • [ISSN] 1195-2199
  • [Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique
  • [ISO-abbreviation] Can J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2687500
  • [Keywords] NOTNLM ; Calcifying epithelioma of Malherbe / Pilomatricoma / Pilomatrixoma
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12. Karkos PD, Khoo LC, Leong SC, Lewis-Jones H, Swift AC: Computed tomography and/or magnetic resonance imaging for pre-operative planning for inverted nasal papilloma: review of evidence. J Laryngol Otol; 2009 Jul;123(7):705-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Computed tomography and/or magnetic resonance imaging for pre-operative planning for inverted nasal papilloma: review of evidence.
  • BACKGROUND: Inverted nasal papilloma is a benign tumour with variable biological behaviour.
  • It is a unique neoplasm and is often difficult to manage, being characterised by a tendency to recur following excision, an association with malignancy and an ability to destroy bone.
  • Radiological diagnosis has traditionally been based on computed tomography, but it is often impossible to differentiate between polyps with entrapped debris and inverted nasal papilloma.
  • Magnetic resonance imaging, especially T2-weighted images, is perhaps a better tool in differentiating inverted nasal papilloma from other nasal lesions, and has recently been advocated as the imaging modality of choice.
  • AIMS: To review the evidence on the ideal imaging modality for pre-operative planning of surgery for patients with histologically proven inverted nasal papilloma.
  • MATERIALS AND METHODS: A systematic review of studies was undertaken, focusing on radiological assessment of inverted nasal papilloma (primary and recurrent).
  • However, we excluded single case reports, case series, pictorial essays, 'teaching' reviews and reviews of inverted nasal papilloma not focusing on pre-operative imaging.
  • CONCLUSIONS: There is currently not enough evidence to suggest one sole modality as providing optimum imaging for inverted nasal papilloma.
  • Computed tomography remains the imaging modality of first choice for inverted nasal papilloma, despite certain disadvantages.
  • Evaluation of sinus tumours usually involves both imaging modalities, and inverted nasal papilloma should be included within this pathological group.
  • A well structured, prospective study is needed to evaluate the efficacy of magnetic resonance imaging versus computed tomography for pre-operative planning of histologically proven inverted nasal papilloma.
  • [MeSH-major] Nose Neoplasms / diagnosis. Papilloma, Inverted / diagnosis

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  • (PMID = 19216815.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 10
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13. Rajan KV, Santhi T: A case of solitary fibrous tumour of the nose and paranasal sinuses. Indian J Otolaryngol Head Neck Surg; 2006 Jul;58(3):316-8
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  • [Title] A case of solitary fibrous tumour of the nose and paranasal sinuses.
  • Solitary fibrous tumours (SFT), formerly known as benign fibrous mesothelioma, are rare mesenchymal spindle cell neoplasms, originally described in the pleura, but now found to arise in many other locations such as mediastinum, urogenital tract, face, nose, paranasal sinuses, orbit, meninges, ear, buccal mucosa, tongue, salivary gland etc.
  • It was first described as a distinct neoplasm in 1931 by Klemperer and Rabin.
  • On reviewing the literature, so far, 21 cases have been reported involving the nose and paranasal sinuses.
  • A case of solitary fibrous tumour of the nose and paranasal sinuses is presented.

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  • (PMID = 23120332.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450392
  • [Keywords] NOTNLM ; Solitary fibrous tumour / paranasal sinuses
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14. Acevedo-Henao CM, Talagas M, Marianowski R, Pradier O: Recurrent inverted papilloma with intracranial and temporal fossa involvement: A case report and review of the literature. Cancer Radiother; 2010 Jun;14(3):202-5
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  • Inverted papilloma (IP) is a rare nasosinusal benign tumour, with epithelium surface inversion to inside the stroma.
  • As a conclusion, inverted papilloma is a benign tumour with an aggressive course, tendency to recurrence and progression to malignancy.
  • [MeSH-major] Nose Neoplasms / pathology. Papilloma / pathology
  • [MeSH-minor] Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Combined Modality Therapy. Disease Progression. Ear, Middle / pathology. Facial Paralysis / etiology. Fatal Outcome. Hearing Loss, Conductive / etiology. Humans. Male. Middle Aged. Nasal Obstruction / etiology. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / surgery. Petrous Bone / pathology. Petrous Bone / surgery. Radiotherapy, Conformal. Reoperation. Temporal Lobe / pathology. Temporal Lobe / surgery

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  • [Copyright] 2010 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.
  • (PMID = 20418144.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 21
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15. Oukabli M, Akhaddar A, Qamouss O, Chahdi H, Rimani M, Albouzidi A: [Nasoethmoidal psammomatoid cemento-ossifiying fibroma with intraorbital extension]. Rev Stomatol Chir Maxillofac; 2010 Feb;111(1):43-5
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  • INTRODUCTION: Psammomatoid cemento-ossifying fibroma (PCOF) is a rare benign fibro-osseous lesion.
  • It affects the maxilla, the nasal cavity, paranasal sinuses, and the ethmoid.
  • It is slow-growing, progressive, and benign but it can be locally extended and mimic a malignant tumor.
  • OBSERVATION: We report the unusual case of a 36-year-old woman with a nasal and ethmoid PCOF with orbital and endocranial extension.
  • The tumor was revealed by exophthalmia and nasal obstruction.
  • [MeSH-major] Ethmoid Sinus / pathology. Fibroma, Ossifying / diagnosis. Nose Neoplasms / diagnosis. Orbital Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Exophthalmos / diagnosis. Female. Humans. Nasal Obstruction / diagnosis. Neoplasm Invasiveness. Skull Neoplasms / diagnosis

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  • (PMID = 19586648.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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16. Ganly I, Gross ND, Patel SG, Bilsky MH, Shah JP, Kraus DH: Outcome of craniofacial resection in patients 70 years of age and older. Head Neck; 2007 Feb;29(2):89-94
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  • Thirty-five patients had a malignant tumor and 1 patient a benign tumor; 15 (42%) had high-grade, 17 (47%) intermediate-grade, and 4 (11%) low-grade pathology.
  • [MeSH-major] Nose Neoplasms / surgery. Postoperative Complications. Salivary Gland Neoplasms / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Age Factors. Aged. Aged, 80 and over. Carcinoma / mortality. Carcinoma / pathology. Carcinoma / surgery. Cranial Fossa, Anterior / surgery. Cranial Fossa, Middle / surgery. Databases as Topic. Esthesioneuroblastoma, Olfactory / mortality. Esthesioneuroblastoma, Olfactory / pathology. Esthesioneuroblastoma, Olfactory / surgery. Female. Follow-Up Studies. Humans. Male. Melanoma / mortality. Melanoma / pathology. Melanoma / surgery. Neoplasm Recurrence, Local. Prospective Studies. Surgical Flaps. Survival Analysis


17. National Toxicology Program: Toxicology and carcinogenesis studies of isoeugenol (CAS No. 97-54-1) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser; 2010 Sep;(551):1-178
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  • The incidences of minimal atrophy of the olfactory epithelium of the nose were significantly increased in 150 mg/kg or greater males and in 300 or 600 mg/kg females.
  • Two male rats in the 300 mg/kg group had rare benign or malignant thymomas, while two other males in this group had rare mammary gland carcinomas.
  • There was a significant positive trend in the incidences of histiocytic sarcoma in females, and this neoplasm occurred in multiple tissues.
  • Exposure to isoeugenol resulted in nonneoplastic lesions of the nose in male and female rats; of the nose, forestomach, and glandular stomach in male and female mice; and of the kidney in female mice.

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  • (PMID = 21372857.001).
  • [ISSN] 0888-8051
  • [Journal-full-title] National Toxicology Program technical report series
  • [ISO-abbreviation] Natl Toxicol Program Tech Rep Ser
  • [Language] eng
  • [Publication-type] Journal Article; Technical Report
  • [Publication-country] United States
  • [Chemical-registry-number] 3T8H1794QW / Eugenol; 97-54-1 / isoeugenol
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18. Orita Y, Hamaya K, Miki K, Sugaya A, Hirai M, Nakai K, Nose S, Yoshino T: Satellite tumors surrounding primary pleomorphic adenomas of the parotid gland. Eur Arch Otorhinolaryngol; 2010 May;267(5):801-6
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  • The occasional local recurrence of benign pleomorphic adenoma (PA) has generally been attributed to the vulnerability of the tumor capsule.
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Genes, p53 / genetics. Humans. Immunohistochemistry. Infant. Infant, Newborn. Ki-67 Antigen / genetics. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Point Mutation / genetics. Preoperative Care

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  • (PMID = 19898859.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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19. Baradaranfar MH, Dabirmoghaddam P: Endoscopic endonasal surgery for resection of benign sinonasal tumors: experience with 105 patients. Arch Iran Med; 2006 Jul;9(3):244-9
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  • [Title] Endoscopic endonasal surgery for resection of benign sinonasal tumors: experience with 105 patients.
  • BACKGROUND: The use of endoscopic surgery for nasal and sinus pathologies has revolutionized our approaches towards the diseases of these areas.
  • OBJECTIVE: To report our experience with endoscopic surgery of benign tumors and tumor-like conditions of the nose and paranasal sinuses.
  • METHODS: The medical records of 105 patients with benign sinonasal tumor, who had undergone endoscopic surgery for removal of their neoplasm between 1997 and 2003, were retrospectively studied.
  • RESULTS: The studied patients included 32 with juvenile nasopharyngeal angiofibroma, 24 with inverted papilloma, 23 with benign fibroosseous lesions, 18 with pyogenic granuloma, 6 with intranasal hemangioma, and 2 with pleomorphic adenoma.
  • CONCLUSION: Endoscopic surgery is a valuable tool for removal of benign tumors of the nose and paranasal sinuses in the hands of an experienced surgeon.

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  • (PMID = 16859060.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Iran
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20. Borghei P, Baradaranfar MH, Borghei SH, Sokhandon F: Transnasal endoscopic resection of juvenile nasopharyngeal angiofibroma without preoperative embolization. Ear Nose Throat J; 2006 Nov;85(11):740-3, 746
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a benign, highly vascular, and locally invasive tumor.
  • [MeSH-minor] Adolescent. Adult. Balloon Occlusion. Blood Loss, Surgical / prevention & control. Child. Humans. Male. Nasal Cavity. Neoplasm Recurrence, Local / surgery. Preoperative Care. Reoperation. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17168151.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Pudszuhn A, Welzel C, Bloching M, Neumann K: Intralesional Cidofovir application in recurrent laryngeal papillomatosis. Eur Arch Otorhinolaryngol; 2007 Jan;264(1):63-70
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  • Recurrent laryngeal papillomatosis is a benign disease of the larynx often leading to organic and functional restrictions.
  • [MeSH-minor] Adult. Aged. Child, Preschool. Combined Modality Therapy. Female. Human papillomavirus 11 / isolation & purification. Human papillomavirus 6 / isolation & purification. Humans. Laryngeal Mucosa / pathology. Laryngeal Mucosa / virology. Laser Therapy. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Remission Induction

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  • (PMID = 17058091.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / Organophosphonates; 8J337D1HZY / Cytosine; JIL713Q00N / cidofovir
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22. Durucu C, Baglam T, Karatas E, Mumbuc S, Kanlikama M: Surgical treatment of inverted papilloma. J Craniofac Surg; 2009 Nov;20(6):1985-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inverted papilloma (IP) is the most common benign tumor of the nose and the paranasal sinuses and constitutes almost 0.5% to 4% of the primary nasal tumors.
  • Nasal obstruction was the most frequent symptom observed in 50 patients (89%).
  • [MeSH-major] Maxillary Sinus Neoplasms / surgery. Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Endoscopy / methods. Ethmoid Sinus / surgery. Female. Humans. Male. Maxilla / surgery. Middle Aged. Nasal Obstruction / surgery. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 19881382.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. El Fakiri MM, Aderdour L, Nouri H, Hassani R, Maliki O, Raji A: [Pleomorphic adenoma of the nasal septum]. Rev Stomatol Chir Maxillofac; 2010 Jun;111(3):162-4
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  • [Title] [Pleomorphic adenoma of the nasal septum].
  • [Transliterated title] L'adénome pléomorphe du septum nasal.
  • INTRODUCTION: The pleomorphic adenoma is the most common benign neoplasm of primary salivary glands.
  • We report a case of pleomorphic adenoma of the nasal septum.
  • CASE REPORT: A 64-year-old man presented with a left rhinological syndrome with nasal obstruction.
  • A facial CT-scan showed a heterogeneous tumor of the nasal septum obstructing the left nasal vestibule.
  • DISCUSSION: The treatment of nasal pleomorphic adenomas must take into account lesion localization, esthetic complications, and evolutionary potential of the lesions.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Nasal Septum / pathology. Nose Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Nasal Obstruction / diagnosis. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20416914.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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24. Roberts J, Shores C, Rose AS: Surgical treatment is warranted in aggressive central giant cell granuloma: a report of 2 cases. Ear Nose Throat J; 2009 Mar;88(3):E8-E13
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  • Central giant cell granuloma (CGCG) is a benign but locally destructive lesion of the mandible or maxilla that presents most often in the second and third decades of life.
  • [MeSH-minor] Adolescent. Disease Progression. Facial Asymmetry. Female. Fibroblasts / pathology. Humans. Magnetic Resonance Imaging. Male. Nasal Cavity / pathology. Nasal Cavity / radiography. Nasal Cavity / surgery. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 19291624.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Ekşi E, Oztop I: Nerve sheath myxoma of the upper lip: a case report. Kulak Burun Bogaz Ihtis Derg; 2010 Nov-Dec;20(6):318-20
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  • Nerve sheath myxoma is a benign tumor that rarely occurs in the lip area.
  • [MeSH-minor] Adult. Cell Division. Female. Humans. Neoplasm Recurrence, Local / prevention & control. S100 Proteins / analysis. Treatment Outcome

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  • (PMID = 20961288.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / S100 Proteins
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26. De Gabory L, Deminière C, Stoll D: [Immunohistochemistry expression of 3 markers (CEA, UEA-I and Ki-67) in nasal inverted papillomas]. Rev Laryngol Otol Rhinol (Bord); 2008;129(3):159-65
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  • [Title] [Immunohistochemistry expression of 3 markers (CEA, UEA-I and Ki-67) in nasal inverted papillomas].
  • [Transliterated title] Expression immunohistochimique de l'ACE, de l'UEA-I et du Ki-67 dans les papillomes inversés naso-sinusiens.
  • OBJECTIVES: Immunohistochemistry evaluation of the expression of degeneration and proliferation markers of the benign form of Schneiderian inverted papillomas in the ORL sphere, in the nondysplastic, dysplastic and degenerated forms.
  • MATERIALS AND METHOD: 44 surgical specimens were analyzed in two groups: A= 33 benign and B= 11 degenerated.
  • A simultaneous bipolar localization belonged to the two groups (nasal, benign and otologic malignant).
  • But, no difference existed between groups A and B, the various sub-groups and the benign specific localizations.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Ki-67 Antigen / analysis. Nose Neoplasms / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology. Plant Lectins / analysis. Sphenoid Sinus / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Child. Diagnosis, Differential. Ear Neoplasms / pathology. Ear Neoplasms / surgery. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nasal Mucosa / pathology. Nasal Polyps / pathology. Nasal Polyps / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Prognosis. Reference Values

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  • (PMID = 19694158.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Plant Lectins; 0 / Ulex europaeus lectins
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27. Koshy S, George M, Gupta A, Daniel RT: Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma. Indian J Dent Res; 2008 Oct-Dec;19(4):366-9
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare vascular neoplasm occurring almost exclusively in adolescent males.
  • Although benign, it is often locally aggressive and can erode into surrounding tissues and structures resulting in significant morbidity and mortality.
  • [MeSH-major] Angiofibroma / surgery. Maxilla / surgery. Nasopharyngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Osteotomy / methods
  • [MeSH-minor] Adolescent. Cranial Fossa, Middle / surgery. Craniotomy / methods. Humans. Male. Neoplasm Invasiveness. Nose Neoplasms / surgery. Palate / surgery. Paranasal Sinus Neoplasms / surgery. Sphenoid Sinus / surgery

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  • (PMID = 19075445.001).
  • [ISSN] 0970-9290
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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28. Constantino Gde T, Abdo TT, Romano FR, Voegels RL, Butugan O: The role of endoscopic surgery in the treatment of nasal inverted papilloma. Braz J Otorhinolaryngol; 2007 Jan-Feb;73(1):65-8
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  • [Title] The role of endoscopic surgery in the treatment of nasal inverted papilloma.
  • The inverted papilloma is a benign neoplasm, prone to malignancy, and bearing a high rate of post-op recurrence.
  • [MeSH-major] Endoscopy / methods. Nose Neoplasms / surgery. Papilloma, Inverted / surgery
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Retrospective Studies. Time Factors. Treatment Outcome

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  • (PMID = 17505601.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Brazil
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29. Emodi O, El-Naaj IA, Gordin A, Akrish S, Peled M: Superficial parotidectomy versus retrograde partial superficial parotidectomy in treating benign salivary gland tumor (pleomorphic adenoma). J Oral Maxillofac Surg; 2010 Sep;68(9):2092-8
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  • [Title] Superficial parotidectomy versus retrograde partial superficial parotidectomy in treating benign salivary gland tumor (pleomorphic adenoma).
  • PURPOSE: Of all benign salivary gland tumors of the parotid gland, pleomorphic adenoma (mixed tumor) is the most common.
  • It accounts for 60% to 70% of all benign tumors of the parotid gland.
  • This neoplasm arises in patients in the fourth to sixth decade of life, with a female predominance.
  • The purpose of our study is to compare 2 surgical techniques performed at the Ear, Nose, and Throat and Maxillofacial Departments, Rambam Medical Center, Haifa, Israel, and determine which is preferable in treating this lesion.

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  • [Copyright] Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20728030.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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30. Miyazaki Y, Ikeda K, Uemura Y, Maehara M, Ohmura N, Sawada S: Non-necrotic invasive squamous cell carcinoma associated with an inverted papilloma: MRI features. Radiat Med; 2006 Feb;24(2):143-6
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  • We present the MRI findings of a carcinoma associated with an inverted papilloma located in the nasal cavity.
  • We found that MRI is unable to distinguish malignant and benign regions in a central mass with no gross necrosis, since this lesion does not alter the basic morphological pattern of inverted papilloma.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Magnetic Resonance Imaging. Nose Neoplasms / pathology. Papilloma, Inverted / pathology
  • [MeSH-minor] Fatal Outcome. Humans. Male. Middle Aged. Neoplasm Invasiveness. Tomography, X-Ray Computed


31. Hirshoren N, Weinberger JM, Neuman T, Ilan O, Ben-Yaakov A: Recurrent vascular leiomyoma of the larynx: clinical and histopathologic characteristics and treatment. Ear Nose Throat J; 2010 Aug;89(8):382-6
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  • Laryngeal vascular leiomyomas are uncommon benign tumors that seldom recur following complete excision.
  • [MeSH-major] Angiomyoma / surgery. Laryngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 20737377.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Eggers G, Eggers H, Sander N, Kössling F, Chilla R: Histological features and malignant transformation of inverted papilloma. Eur Arch Otorhinolaryngol; 2005 Apr;262(4):263-8
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  • Inverted papilloma (IP) is a primarily benign epithelial neoplasm with a propensity to transform to squamous cell carcinoma (SCC).
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / pathology. Papilloma, Inverted / pathology

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  • (PMID = 15258811.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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33. Iseh KR, Aliyu D: Surgical considerations in the management of tumours of the nose and paranasal sinuses in a Northern Nigerian Teaching Hospital. West Afr J Med; 2009 Nov-Dec;28(6):371-5
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  • [Title] Surgical considerations in the management of tumours of the nose and paranasal sinuses in a Northern Nigerian Teaching Hospital.
  • BACKGROUND: Tumours of the nose and paranasal sinuses in sub-Saharan Africa are generally characterised by late presentation posing management challenges to the otorhinolaryngologists in the sub-region.
  • OBJECTIVES: To appraise surgical considerations in the management of tumours of the nose and paranasal sinuses in a developing nation from the experiences of an Ear, Nose, and Throat Department of a Nigerian Teaching Hospital.
  • METHODS: This was a chart review of patients with tumours of the nose and paranasal sinuses who underwent various surgical operations over a period of four and a half years.The patients were referred by other physicians or health care workers.
  • In 46(83.6%) patients the tumours had extended beyond the nasal cavity or one sinus cavity to contiguous structures.
  • The surgical operations carried out were lateral rhinotomy in 37(57.8%), intranasal clearance and intranasal antrostomy in 16(25%), total maxillectomy in seven(11%), and anterior craniofacial resection in two (3.1%) patients.The histological examination showed that 43 (78.2%) cases were benign, while 12 (21.8%) cases were malignant.
  • Poverty, ignorance, inadequate funding and administration challenges of health resources are factors militating against proper clinical management of tumours of the nose and paranasal sinuses in developing nations.
  • [MeSH-major] Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Child. Child, Preschool. Female. Follow-Up Studies. Hospitals, Teaching. Humans. Male. Middle Aged. Neoplasm Staging. Nigeria / epidemiology. Otorhinolaryngologic Surgical Procedures / methods. Sex Distribution. Socioeconomic Factors. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 20486095.001).
  • [ISSN] 0189-160X
  • [Journal-full-title] West African journal of medicine
  • [ISO-abbreviation] West Afr J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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34. Becker S, Schön R, Gutwald R, Otten JE, Maier W, Hentschel R, Jüttner E, Gellrich NC: A congenital teratoma with a cleft palate: report of a case. Br J Oral Maxillofac Surg; 2007 Jun;45(4):326-7
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  • Teratomas are benign tumors containing cells from ectodermal, mesodermal and endodermal layers.
  • Size and location of the neoplasm in the oronasopharynx is variable.
  • [MeSH-minor] Female. Follow-Up Studies. Humans. Infant, Newborn. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / congenital. Nose Neoplasms / pathology

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  • (PMID = 16377040.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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35. Bozzo C, Garrel R, Meloni F, Stomeo F, Crampette L: Endoscopic treatment of antrochoanal polyps. Eur Arch Otorhinolaryngol; 2007 Feb;264(2):145-50
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  • The antrochoanal polyp (Killian polyp) is an infrequent, benign neoplasm, which arises from the maxillary sinus to reach the ipsilateral choana.
  • [MeSH-major] Endoscopy / methods. Nasal Polyps / surgery. Nose Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Eosinophilia / epidemiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

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  • (PMID = 17013627.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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36. Łukomski M, Obrebka R, Starska K, Pietruszewska W, Durko M, Pajor A, Gryczyński M, Józefowicz-Korczyńska M: [Results of treatment papilloma of nasal cavity and paranasal sinuses]. Otolaryngol Pol; 2008;62(5):574-7
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  • [Title] [Results of treatment papilloma of nasal cavity and paranasal sinuses].
  • INTRODUCTION: Papilloma of the nose and paranasal sinuses is a benign tumor originated from nose mucosa.
  • The aim of the study was the analysis of clinical and treatment outcomes of patients with papilloma of the nose and paranasal sinuses.
  • MATERIAL AND METHODS: The retrospective analysis was curried out on 41 patients--16 with papiloma of the nasal vestibule and 25 with inverted papilloma the nose and paranasal sinuses surgically treated in I ENT Clinic Medical University in Lodz between 1998-2004 years.
  • RESULTS: The most frequent complains was increasing unilateral nasal obstruction and rhinorhea.
  • Nasal vestibule papilloma were intranasal removed in all cases.
  • In extended tumor nose and paranasal sinuses in 14 cases intranasal procedures, in 7 sublabial approached, in 4 lateral rhynothomy were performed.
  • [MeSH-major] Neoplasm Recurrence, Local. Nose Neoplasms / surgery. Papilloma / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 19004260.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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37. Czecior E, Namysłowski G, Misiołek M, Scierski W, Polok A, Lisowska G, Mrówka-Kata K, Orecka B, Pawlas P: [Strategy of the sinonasal tumors treatment]. Otolaryngol Pol; 2007;61(4):559-61
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  • RESULTS: In the histological examination in 4 patients the benign neoplasm and in 22 patients malignant tumors were diagnosed.
  • On the basis of the CT and MRI examination as well as the description of the surgical procedure we stated that in 13 cases the primary localization of neoplasm was the maxillary sinus, in 5 cases ethmoidal cells, in 3 nasal cavity.
  • In one patient the estimation of primary tumor localization was not possible, because of the very large extension of the neoplasm.
  • In 8 patients with the infiltration of lateral nasal wall the medial maxillectomy were performed.
  • [MeSH-major] Nose Neoplasms / diagnosis. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18260251.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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38. Pośpiech L, Gawron W, Rak J, Bochnia M: [Nasal glioma--case report]. Otolaryngol Pol; 2005;59(5):767-9
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  • [Title] [Nasal glioma--case report].
  • Benign congenital lesions resulting from the deficient regression of neuroglial tissue in normal embryonic development are called gliomas.
  • We present a case of the 9-year-old boy treated in the ENT Department of Wroclaw Medical University with the initial diagnosis of nasal polyposis or tumour which appeared to be glioma in the postoperative histological evaluation.
  • We conclude that each doctor has to be aware of possible neoplasm even in the youngest groups of the patients.
  • [MeSH-major] Glioma / diagnosis. Glioma / surgery. Nose Neoplasms / diagnosis. Nose Neoplasms / surgery
  • [MeSH-minor] Child. Diagnosis, Differential. Humans. Male. Nasal Obstruction / etiology. Nasal Obstruction / surgery. Nasal Polyps / diagnosis. Treatment Outcome

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  • (PMID = 16471200.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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39. Prasad K, Rao SG, Harish K: Giant cell tumor of the temporal bone--a case report. BMC Ear Nose Throat Disord; 2005 Sep 15;5:8
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  • BACKGROUND: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull.

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  • (PMID = 16162299.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1253509
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40. Dave SP, Bared A, Casiano RR: Surgical outcomes and safety of transnasal endoscopic resection for anterior skull tumors. Otolaryngol Head Neck Surg; 2007 Jun;136(6):920-7
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  • There were 17 malignant and two benign lesions.
  • [MeSH-major] Carcinoma / surgery. Cranial Fossa, Anterior / surgery. Endoscopy. Esthesioneuroblastoma, Olfactory / surgery. Hemangiopericytoma / surgery. Meningeal Neoplasms / surgery. Meningioma / surgery. Nose Neoplasms / surgery. Postoperative Complications / etiology. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Survival Rate

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  • (PMID = 17547980.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Heathcote KJ, Nair SB: The impact of modern techniques on the recurrence rate of inverted papilloma treated by endonasal surgery. Rhinology; 2009 Dec;47(4):339-44
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  • Sinonasal inverted papilloma (IP) is a benign epithelial tumour which displays aggressive local behaviour, has a high local recurrence rate and the potential for malignant transformation.
  • [MeSH-major] Neoplasm Recurrence, Local / epidemiology. Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Papilloma, Inverted / surgery
  • [MeSH-minor] Endoscopy. Humans. Nasal Cavity. Neoplasm Staging

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  • (PMID = 19936355.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 54
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42. Sołtys J, Pietniczka-Załeska M, Młyńczyk-Budzynowska K, Majkowski J: [Neoplasms of paranasal sinuses in material of ENT Department MSS Hospital in Warsaw between 2006-2007]. Otolaryngol Pol; 2008;62(4):451-4
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  • THE RESULTS: We detected the following:--benign neoplasms: 2 cases of angiofibroma, 3 cases of inverted papilloma;--malignant tumors: 4 cases of Ca planoepitheliale, 1 instance of adenocarcinoma, 1 instance of Ca anaplasticum, 1--melanoma, 1--esthesioneuroblastoma, 1--lymphoma malignum, 1--metastatic tumor.
  • [MeSH-major] Carcinoma / diagnosis. Nose Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Hospitals, Public. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Otorhinolaryngologic Surgical Procedures / methods. Poland. Retrospective Studies. Treatment Outcome

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  • (PMID = 18837222.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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43. Han Z, Lin GJ, Chi FL, Wang SY, Huang JM, Liu HJ, Zhang LR: The relationship between the extracellular matrix and the angiogenesis and metastasis of laryngeal carcinoma. ORL J Otorhinolaryngol Relat Spec; 2008;70(6):352-8
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  • METHODS: Thirty-three cases of benign and malignant laryngeal tumors were included.
  • RESULTS: The expression of ECM1 (p = 0.004) and HA (p = 0.036) was significantly different between benign and malignant tumors.
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Metastasis. Neoplasm Staging. Probability. Prognosis. Risk Assessment. Sampling Studies. Sensitivity and Specificity. Statistics, Nonparametric. Survival Analysis

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18984970.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ECM1 protein, human; 0 / Extracellular Matrix Proteins
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44. Ridder GJ, Behringer S, Kayser G, Pfeiffer J: [Malignancies arising in sinonasal inverted papillomas]. Laryngorhinootologie; 2008 Nov;87(11):783-90
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  • [Transliterated title] Malignome auf dem Boden invertierter Papillome der Nase und Nasennebenhöhlen *
  • BACKGROUND: Inverted papillomas are primarily benign neoplasms that occur in the nasal cavity and paranasal sinuses.
  • Comparison was made between the group of patients with inverted papillomas and associated squamous cell carcinomas and the group of patients with benign inverted papillomas.
  • Our data suggest, that the association between carcinoma and inverted papilloma is indirect and that the gradual progression from inverted papilloma to a malignant neoplasm is if at all infrequent.
  • [MeSH-major] Carcinoma, Squamous Cell. Neoplasms, Multiple Primary. Neoplasms, Second Primary. Nose Neoplasms. Papilloma, Inverted. Paranasal Sinus Neoplasms. Sphenoid Sinus
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Maxillary Sinus / pathology. Maxillary Sinus Neoplasms / pathology. Maxillary Sinus Neoplasms / surgery. Middle Aged. Neoplasm Staging. Nose / pathology. Retrospective Studies. Risk Factors. Time Factors

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  • (PMID = 18633858.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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45. Durden FL Jr, Moore CE, Muller S: Verrucous carcinoma of the paranasal sinuses: a case report. Ear Nose Throat J; 2010 Jul;89(7):E21-3
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  • The tumor grows locally invasive but is histologically benign and metastasizes rarely.
  • To date, 22 cases of verrucous carcinoma involving the nasal cavity and/or the paranasal sinuses have been reported.
  • We present a case of verrucous carcinoma involving the paranasal sinuses, nasal cavity, cranium, and orbit.
  • [MeSH-minor] Biopsy. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiation effects. Nasal Cavity / surgery. Neoplasm Invasiveness. Neoplasm Staging. Orbital Neoplasms / pathology. Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Skull / pathology. Skull / radiation effects. Skull / surgery. Skull Neoplasms / pathology. Skull Neoplasms / radiotherapy. Skull Neoplasms / surgery

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  • (PMID = 20628974.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Silkiss RZ, Mudvari SS, Shetlar D: Ophthalmologic presentation of nasal chondromesenchymal hamartoma in an infant. Ophthal Plast Reconstr Surg; 2007 May-Jun;23(3):243-4
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  • [Title] Ophthalmologic presentation of nasal chondromesenchymal hamartoma in an infant.
  • Pathologic examination confirmed the diagnosis of nasal chondromesenchymal hamartoma.
  • Ophthalmologists may be among the first medical practitioners to encounter nasal chondromesenchymal hamartoma, a rare, benign neoplasm of the nasal and paranasal sinuses.

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  • (PMID = 17519672.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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47. Kohl SK, Simpson RJ, Wisecarver J: Chondroid metaplasia mimicking recurrent squamous cell carcinoma of the head and neck. Ear Nose Throat J; 2009 Jan;88(1):E4
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  • The tongue lesion was excised, and pathologic examination identified a submucosal focus of benign-appearing cartilage.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Neoplasm Recurrence, Local / pathology. Tongue Neoplasms / secondary. Tonsillar Neoplasms / pathology

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  • (PMID = 19172559.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Biswas D, Saha S, Bera SP: Relative distribution of the tumours of ear, nose and throat in the paediatric patients. Int J Pediatr Otorhinolaryngol; 2007 May;71(5):801-5
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  • [Title] Relative distribution of the tumours of ear, nose and throat in the paediatric patients.
  • RESULTS: Forty-three patients of above age group with a neoplasm of the otolaryngological region were managed in our department, the incidence was 0.5%.
  • The ratio of benign to malignant lesion was 7.6:1.
  • The commonest site of neoplasm was the nose and paranasal sinuses (13 cases, 30%).

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  • (PMID = 17368816.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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49. Yazdani N, Khorsandi-Ashtiani M, Rabbani-Anari M, Bassam A, Kouhi A: Nasal vestibular huge keratoacanthoma: an unusual site. Pak J Biol Sci; 2009 Oct 15;12(20):1385-7
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  • [Title] Nasal vestibular huge keratoacanthoma: an unusual site.
  • Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence.
  • In this study, we excised a mass of nasal vestibule, a site far away sun-exposure.
  • To our knowledge, this is the first case of nasal vestibular keratoacanthoma.
  • For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management.
  • [MeSH-major] Keratoacanthoma / pathology. Nasal Cavity / pathology. Nose Diseases / pathology. Skin Diseases / pathology


50. Chmielik LP, Frackiewicz M, Krajewski R, Woloszczuk-Gebicka B, Chmielik M: Perioperative problems and treatment of a teenager with a juvenile angiofibroma refusing blood transfusion. Int J Pediatr Otorhinolaryngol; 2009 May;73(5):689-92
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  • OBJECTIVES: Juvenile angiofibroma is a benign, non-encapsulated neoplasm, consisting of vascular and connective tissue.
  • [MeSH-major] Angiofibroma / surgery. Blood Transfusion. Neoplasms, Connective Tissue / surgery. Nose Neoplasms / surgery. Postoperative Care. Preoperative Care. Treatment Refusal. Vascular Neoplasms / surgery
  • [MeSH-minor] Adolescent. Female. Gonads / physiopathology. Hemodilution. Humans. Magnetic Resonance Imaging. Male. Monitoring, Intraoperative. Nasal Cavity. Pituitary Gland / physiopathology

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  • (PMID = 19230984.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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51. Benbenisty KM, Andea A, Metcalf J, Cook J: Atypical cellular neurothekeoma treated with Mohs micrographic surgery. Dermatol Surg; 2006 Apr;32(4):582-7; discussion 587
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  • BACKGROUND: Atypical cellular neurothekeoma is a rare neoplasm generally regarded as a benign tumor with locally aggressive behavior.
  • OBJECTIVE: The objective was to report a case of atypical cellular neurothekeoma of the nasal ala in a young woman treated by Mohs micrographic surgery.
  • RESULTS: The neoplasm was extirpated in a three-stage, five section Mohs surgery procedure.
  • [MeSH-major] Mohs Surgery. Neurothekeoma / surgery. Nose Neoplasms / surgery

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  • [CommentIn] Dermatol Surg. 2008 Mar;34(3):428 [18248473.001]
  • (PMID = 16681671.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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52. Depondt J, Shabana el-H, Walker F, Pibouin L, Lezot F, Berdal A: Nasal inverted papilloma expresses the muscle segment homeobox gene Msx2: possible prognostic implications. Hum Pathol; 2008 Mar;39(3):350-8
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  • [Title] Nasal inverted papilloma expresses the muscle segment homeobox gene Msx2: possible prognostic implications.
  • Nasal inverted papilloma is a rare benign tumor of epithelial origin with aggressive evolution, bone destruction, recurrence, and malignant transformation.
  • Using reverse transcriptase-polymerase chain reaction and immunohistochemistry, Msx2 expression was examined in nasal inverted papilloma and in nontumorigenic tissue counterparts.
  • For the first time, Msx2 was detected in all inverted papillomas but not in the nasal polyps or in the normal mucosa.
  • [MeSH-major] Biomarkers, Tumor / analysis. DNA-Binding Proteins / biosynthesis. Homeodomain Proteins / biosynthesis. Nose Neoplasms / genetics. Nose Neoplasms / metabolism. Papilloma, Inverted / genetics. Papilloma, Inverted / metabolism
  • [MeSH-minor] Acid Phosphatase / metabolism. Adult. Aged. Female. Gene Expression. Genes, Homeobox / physiology. Humans. Immunohistochemistry. Isoenzymes / metabolism. Male. Middle Aged. Neoplasm Recurrence, Local / genetics. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / pathology. Prognosis. RANK Ligand / biosynthesis. RNA, Messenger / analysis. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 18187185.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Homeodomain Proteins; 0 / Isoenzymes; 0 / MSX2 protein; 0 / RANK Ligand; 0 / RNA, Messenger; 0 / TNFSF11 protein, human; EC 3.1.3.- / tartrate-resistant acid phosphatase; EC 3.1.3.2 / Acid Phosphatase
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53. Eggers G, Mühling J, Hassfeld S: Inverted papilloma of paranasal sinuses. J Craniomaxillofac Surg; 2007 Jan;35(1):21-9
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  • INTRODUCTION: Inverted papilloma (Schneiderian papilloma) is a primarily benign lesion that occurs in the nasal cavity and paranasal sinuses.
  • STUDY DESIGN: This is a review including a short introduction to the different histological types of nasal papilloma, their pathogenesis and the clinical and histopathological diagnosis.
  • [MeSH-minor] Cell Transformation, Neoplastic / pathology. Humans. Nasal Cavity / pathology. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / pathology. Prognosis

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  • (PMID = 17267229.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Scotland
  • [Number-of-references] 109
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54. Holsinger FC, Hafemeister AC, Hicks MJ, Sulek M, Huh WW, Friedman EM: Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review. Ear Nose Throat J; 2010 Nov;89(11):534-40
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  • [Title] Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review.
  • We conducted a retrospective case-series review to identify the various diagnoses of neoplasms of the nasal cavity and paranasal sinuses in a pediatric population.
  • All patients had been diagnosed with a tumor of the nasal cavity or paranasal sinuses between Jan.
  • Lesions included adnexal neoplasm, ameloblastic fibro-odontoma, basal cell carcinoma, benign fibrous histiocytoma, blue nevus, chondrosarcoma, compound nevus, epithelioma adenoides cysticum, esthesioneuroblastoma, Ewing sarcoma, fibrosarcoma, giant cell granuloma, granulocytic sarcoma, hemangioma, hemangiopericytoma, Langerhans cell histiocytosis, lymphangioma, lymphoma, melanoma, neuroblastoma, neurofibroma, ossifying osteofibroma, osteochondroma, osteosarcoma, port wine stain, rhabdomyosarcoma, Spitz nevus, and xanthogranuloma.
  • We believe that the large size of this study and the data on disease incidence will allow clinicians to be better informed of the differential diagnosis of neoplasms of the nasal cavity and paranasal sinuses in the pediatric population.
  • [MeSH-major] Nasal Cavity. Nose Neoplasms / epidemiology. Paranasal Sinus Neoplasms / epidemiology


55. Eversole R, Su L, ElMofty S: Benign fibro-osseous lesions of the craniofacial complex. A review. Head Neck Pathol; 2008 Sep;2(3):177-202
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  • [Title] Benign fibro-osseous lesions of the craniofacial complex. A review.
  • Benign fibro-osseous lesions of the craniofacial complex are represented by a variety of disease processes that are characterized by pathologic ossifications and calcifications in association with a hypercellular fibroblastic marrow element.
  • [MeSH-minor] DNA, Neoplasm / analysis. Humans. Mutation

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  • (PMID = 20614314.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ PMC2807558
  • [Keywords] NOTNLM ; Benign fibroosseous lesions / Cementoma / Cementoosseous dysplasia / Fibrous dysplasia / Ossifying fibroma / Osteitis deformans
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56. Lane AP, Bolger WE: Endoscopic management of inverted papilloma. Curr Opin Otolaryngol Head Neck Surg; 2006 Feb;14(1):14-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE OF REVIEW: Inverted papillomas are uncommon benign tumors that may occur in the sinonasal tract.
  • [MeSH-major] Endoscopy. Nose Neoplasms / surgery. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Cell Transformation, Neoplastic / pathology. Clinical Competence. Cohort Studies. Follow-Up Studies. Humans. Outcome and Process Assessment (Health Care). Serpins / analysis

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  • (PMID = 16467632.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Serpins; 0 / squamous cell carcinoma-related antigen
  • [Number-of-references] 30
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57. Schmidt M, Dietlein M, Schröder U, Schicha H: False-positive uptake of I-131 in a laryngocele mimicking thyroid remnant after thyroidectomy for papillary thyroid carcinoma. Clin Nucl Med; 2006 Nov;31(11):716-7
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  • Further examination of the patient in the ear, nose and throat department confirmed the finding of a laryngocele and biopsies demonstrated benign tissue.
  • [MeSH-major] Carcinoma, Papillary / radionuclide imaging. Iodine Radioisotopes. Laryngeal Diseases / radionuclide imaging. Neoplasm Recurrence, Local / radionuclide imaging. Thyroid Neoplasms / radionuclide imaging

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  • (PMID = 17053394.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals
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58. Derin AT, Güney K, Turhan M, Erdoğan A, Ağirdir BV: Giant cervical lipoma invading carotid artery: a case report. Kulak Burun Bogaz Ihtis Derg; 2009 Jan-Feb;19(1):28-31
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  • Lipomas are one of the most frequently encountered benign tumors in any location.
  • [MeSH-minor] Blood Vessel Prosthesis. Humans. Male. Middle Aged. Neoplasm Invasiveness. Treatment Outcome

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  • (PMID = 19793044.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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59. Mansueto G, Falleti J, De Cecio R, Papa F, De Rosa G: Synchronous bilateral multifocal canalicular adenoma: a case report of an unusual finding. Clin Exp Dermatol; 2009 Dec;34(8):e587-9
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  • Canalicular adenoma is a benign neoplasm of the minor salivary glands.
  • We report a case of a 78-year-old woman with CA of the nasolabial wrinkle on both sides of the nose, which occurred at the same time.
  • [MeSH-major] Adenoma / pathology. Nose Neoplasms / pathology. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Female. Humans. Neoplasm Recurrence, Local. Salivary Glands, Minor / pathology

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  • (PMID = 19486066.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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60. Kim CW, Oh SJ, Rho YS, Cho SJ, Koh ES: A case of dysplastic nevus of the external auditory canal presenting with conductive hearing loss. Yonsei Med J; 2009 Dec 31;50(6):845-7
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  • A nevus which is a benign melanocytic neoplasm rarely occurs within the external auditory canal (EAC).

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  • (PMID = 20046428.001).
  • [ISSN] 1976-2437
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2796414
  • [Keywords] NOTNLM ; External auditory canal / conductive hearing loss / dysplastic nevus / intradermal nevus
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61. Vranic S, Caughron SK, Djuricic S, Bilalovic N, Zaman S, Suljevic I, Lydiatt WM, Emanuel J, Gatalica Z: Hamartomas, teratomas and teratocarcinosarcomas of the head and neck: Report of 3 new cases with clinico-pathologic correlation, cytogenetic analysis, and review of the literature. BMC Ear Nose Throat Disord; 2008;8:8
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  • METHODS: We describe here two new cases of multilineage tumors including sinonasal teratocarcinosarcoma [SNTCS], and congenital oronasopharyngeal teratoma (epignathus) and compare their features with those of a new case of a rare salivary gland anlage tumor [SGAT], an entity for which the pathogenesis is unclear (i.e. hamartoma versus neoplasm).
  • Both cytogenetic abnormalities are characteristically present in malignant germ cell tumors providing for the first time evidence that this rare tumor type indeed might represent a variant of a germ cell neoplasm.
  • The SGAT and epignathus carried no such cytogenetic abnormalities, in keeping with their limited and benign biologic potential.
  • Malignant tumors of germ cell origins are more likely to affect adults with insidious symptom development, while benign tumors can nevertheless cause dramatic clinical symptoms which, under certain circumstances, can be fatal.

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  • (PMID = 19025657.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2611960
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62. Salem F, Rosenblum MK, Jhanwar SC, Kancherla P, Ghossein RA, Carlson DL: Teratocarcinosarcoma of the nasal cavity and paranasal sinuses: report of 3 cases with assessment for chromosome 12p status. Hum Pathol; 2008 Apr;39(4):605-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Teratocarcinosarcoma of the nasal cavity and paranasal sinuses: report of 3 cases with assessment for chromosome 12p status.
  • Sinonasal teratocarcinosarcoma (SNTCS) is a rare malignant neoplasm with 63 reported cases to date.
  • Microscopic examination revealed admixed epithelial and mesenchymal elements in all 3 cases; benign squamous and glandular epithelium and neuroepithelial tissue were identified, the squamous epithelium demonstrating "fetal-like" cytoplasmic clearing.
  • Our findings suggest that 12p amplification, if it occurs at all in this setting, is exceptional and that SNTCS is a somatic-type neoplasm exhibiting divergent differentiation rather than a germ cell tumor.
  • [MeSH-major] Carcinosarcoma / etiology. Chromosome Aberrations. Chromosomes, Human, Pair 12 / genetics. Nasal Cavity. Nose Neoplasms / etiology. Paranasal Sinus Neoplasms / etiology. Teratocarcinoma / etiology

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  • (PMID = 18284932.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Marzano AV, Ghislanzoni M, Gianelli U, Caputo R, Alessi E, Berti E: Fatal CD8+ epidermotropic cytotoxic primary cutaneous T-cell lymphoma with multiorgan involvement. Dermatology; 2005;211(3):281-5
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  • A 70-year-old woman presented with a 3-month history of two ulcerated erythematous-violaceous nodular lesions over the nose and forehead, respectively.
  • At that time, despite the diagnosis of a benign disease, an adequate staging was performed, ruling out any extracutaneous involvement.
  • [MeSH-minor] Aged. Antigens, CD8 / immunology. Fatal Outcome. Female. Femoral Artery. Humans. Neoplasm Metastasis. Thrombosis / etiology

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 16205076.001).
  • [ISSN] 1018-8665
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antigens, CD8
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64. Hadar T, Shvero J, Yaniv E, Shvili I, Leabu M, Koren R: Human topoisomerase II-alpha is highly expressed in sinonasal-inverted papilloma, but not in inflammatory polyp. J Cell Mol Med; 2008 Sep-Oct;12(5A):1551-8
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  • Sinonasal-inverted papilloma is a benign tumour with a high rate of recurrence, but possible malignant transformation.
  • Our goal was to investigate by immunochemistry the expression level of topoII-in inverted papilloma, inflammatory nasal polyp and normal sinonasal epithelium and to compare it with expression level of Ki67.
  • In inflammatory nasal polyp group, topoII-alpha index was 2.4 +/- 2.1, and the difference in the topoII-alpha index between inverted papilloma and inflammatory polyp group was also statistically significant.
  • In the inflammatory nasal polyp group Ki67 index was 5.9 +/- 3.4.
  • The difference in th Ki67 index between inverted papilloma and inflammatory nasal polyp groups was statistically significant.
  • [MeSH-major] Antigens, Neoplasm / metabolism. DNA Topoisomerases, Type II / metabolism. DNA-Binding Proteins / metabolism. Nose Neoplasms / enzymology. Nose Neoplasms / pathology. Papilloma, Inverted / enzymology. Papilloma, Inverted / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Epithelium / enzymology. Female. Humans. Inflammation / enzymology. Inflammation / pathology. Ki-67 Antigen / metabolism. Male. Middle Aged. Nasal Polyps / enzymology. Nasal Polyps / pathology

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  • (PMID = 18544048.001).
  • [ISSN] 1582-1838
  • [Journal-full-title] Journal of cellular and molecular medicine
  • [ISO-abbreviation] J. Cell. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / DNA-Binding Proteins; 0 / Ki-67 Antigen; EC 5.99.1.3 / DNA Topoisomerases, Type II; EC 5.99.1.3 / DNA topoisomerase II alpha
  • [Other-IDs] NLM/ PMC3918071
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65. Laga AC, Tajirian AL, Islam MN, Bhattacharyya I, Cohen DM, Plamondon CJ, Robinson-Bostom L: Myopericytoma: report of two cases associated with trauma. J Cutan Pathol; 2008 Sep;35(9):866-70
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  • We present two cases of myopericytoma associated with trauma: a 64-year-old man who developed several nodules on his nose four months after sustaining multiple abrasions to his forehead and nose, and a 72-year-old woman with a solitary growth in the alveolar ridge of unknown duration.
  • Despite sharing morphologic features with angioleiomyoma, myofibroma and glomus tumor, myopericytoma is thought to represent a distinct perivascular myoid neoplasm of skin and soft tissues.
  • Most cases of myopericytoma are benign, however, local recurrence and malignancy have recently been reported, Myopericytoma can be multifocal involving a single or multiple anatomic regions, and tends to occur in dermal and superficial soft tissues of adults primarily on the extremities.
  • Our cases are unusual examples of myopericytoma manifesting as multiple nodules on the nose, and a solitary growth on the buccal mucosa after trauma.
  • [MeSH-minor] Actins / metabolism. Aged. Biomarkers, Tumor / metabolism. Calcium-Binding Proteins / metabolism. Female. Humans. Male. Microfilament Proteins / metabolism. Middle Aged. Mouth Mucosa / injuries. Myosin Heavy Chains / metabolism. Nose / injuries. Treatment Outcome

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  • (PMID = 18494828.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Microfilament Proteins; 0 / calponin; EC 3.6.4.1 / Myosin Heavy Chains
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66. Banhiran W, Casiano RR: Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm. Curr Opin Otolaryngol Head Neck Surg; 2005 Feb;13(1):50-4
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  • [Title] Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm.
  • With increased skill with endoscopic surgical technique, advanced technologies such as intraoperative imaging systems, and a better understanding of the complex anatomy of the paranasal sinuses and surrounding vital structures, many otolaryngologists have increasingly applied their expertise in endoscopic sinus surgery to the resection of nasal and sinus neoplasms.
  • The following represents a review of the recent literature on the latest trends regarding endoscopic resection of nasal and paranasal sinus neoplasms.
  • RECENT FINDINGS: There has been an increasing popularity in the removal of nasal and paranasal sinus neoplasms through an endoscopic approach.
  • In the recent literature, emphasis has been on the endoscopic surgery of benign tumors, especially inverted papilloma and nasopharyngeal angiofibroma.
  • Other benign neoplasms have also been reported, but only in small case reports.
  • Especially for the more common benign neoplasms, such as inverted papilloma and early stage angiofibroma.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 15654216.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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67. Jurkiewicz D, Syryło A, Chomicki A, Koktysz R: [Endoscopic surgery in treatment of inverted papilloma nose et paranasal sinuses in the older patient]. Otolaryngol Pol; 2007;61(2):198-202
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  • [Title] [Endoscopic surgery in treatment of inverted papilloma nose et paranasal sinuses in the older patient].
  • Inverted papilloma is a benign neoplasm of uncertain ethiology.
  • In this work was described one case of 102 year's old patient with unilateral nasal obstruction since 5 month and headache.
  • [MeSH-major] Endoscopy. Nasal Cavity / surgery. Nose Neoplasms / surgery. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 17668811.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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68. Díaz Molina JP, Llorente Pendas JL, Rodrigo Tapia JP, Alvarez Marcos C, Obeso Agüera S, Suárez Nieto C: [Inverted sinonasal papillomas. Review of 61 cases]. Acta Otorrinolaringol Esp; 2009 Nov-Dec;60(6):402-8
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  • [Transliterated title] Papilomas invertidos rinosinusales. Revisión de 61 casos.
  • INTRODUCTION: Inverted papillomas are benign sinonasal lesions that arise primarily from the lateral nasal wall which are characterized by their tendency to recur and propensity to be associated with malignancy.
  • The most common symptom was unilateral nasal obstruction in 91% of the cases, followed by rhinorrhea in 46%.
  • The most frequent location was the ethmoid region in 51% of cases, followed by the maxillary sinus in 28% and the lateral nasal wall in 21% of the cases.
  • [MeSH-major] Nose Neoplasms / epidemiology. Papilloma, Inverted / epidemiology. Paranasal Sinus Neoplasms / epidemiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / epidemiology. Comorbidity. Diagnostic Imaging. Disease Progression. Female. Humans. Male. Middle Aged. Nasal Polyps / epidemiology. Neoplasm Recurrence, Local. Neoplasm Staging. Retrospective Studies. Sinusitis / epidemiology. Spain / epidemiology. Young Adult

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  • (PMID = 19909715.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 24
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69. Liu FH, Hsueh C, Chao TC, Lin JD: Neck nodule and thyroid cancer in young without radiation exposure history. Pediatr Surg Int; 2009 Sep;25(9):785-8
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  • RESULTS: Of the 234 cases, 187 (79.9%) were surgically confirmed to be benign lesions, including four cases that were diagnosed as atypical adenoma.
  • Except in cases of follicular thyroid neoplasm, neck ultrasonography with FNAC could effectively identify the thyroid or non-thyroid origin of these masses with high-diagnostic accuracy.

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  • (PMID = 19629501.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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70. Sharma V, Koirala K: Lateral rhinotomy vs mid-facial degloving for T3 inverted papilloma of nose and paranasal sinus. Nepal Med Coll J; 2009 Jun;11(2):115-7
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  • [Title] Lateral rhinotomy vs mid-facial degloving for T3 inverted papilloma of nose and paranasal sinus.
  • Inverted papillomas are rare, benign epithelial tumours of the nasal cavity and paranasal sinuses.
  • All patients initially underwent nasal biopsy for confirmation of the diagnosis and pre-operative C.T. scan for tumour staging.
  • Commonest presenting complaint was unilateral nasal obstruction (60.0% in group I, 80.0% in group II).
  • [MeSH-major] Nose Neoplasms / surgery. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Aged. Biopsy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 19968152.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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71. de Ru JA, van Leeuwen MS, van Benthem PP, Velthuis BK, Sie-Go DM, Hordijk GJ: Do magnetic resonance imaging and ultrasound add anything to the preoperative workup of parotid gland tumors? J Oral Maxillofac Surg; 2007 May;65(5):945-52
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  • PATIENTS AND METHODS: Prospectively, 99 patients with 77 benign and 22 malignant lesions were included; 82 underwent parotidectomy.
  • Cytology correctly predicted the benign or malignant nature of the tumor in all cases.
  • CONCLUSION: FNAC is the only accurate investigation for classifying a parotid gland tumor as benign or malignant.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Facial Nerve / anatomy & histology. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neoplasm Staging / methods. Parotid Gland / anatomy & histology. Parotid Gland / innervation. Physical Examination. Reference Standards. Single-Blind Method

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  • (PMID = 17448846.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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72. Kung B, Aftab S, Wood M, Rosen D: Malignant melanoma metastatic to the thyroid gland: a case report and review of the literature. Ear Nose Throat J; 2009 Jan;88(1):E7
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  • Patients who present with a thyroid nodule and who have a history of malignancy present a diagnostic dilemma: Is the nodule benign, a new primary, or a distant metastasis?
  • [MeSH-major] Melanoma / secondary. Neoplasm Invasiveness / pathology. Thyroid Neoplasms / secondary. Thyroid Nodule / pathology
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Follow-Up Studies. Humans. Immunohistochemistry. Lymph Nodes / pathology. Male. Neck Dissection. Neoplasm Staging. Risk Assessment. Thyroidectomy / methods. Treatment Outcome

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  • (PMID = 19172560.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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73. Dao LN, Scheithauer BW, Erlandson RA, Young WF Jr, Aidan Carney J: Divergent myoid, neuroendocrine, and perineural differentiation in a nasal tumor of a patient with Carney complex. Am J Surg Pathol; 2008 Jan;32(1):167-71
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  • [Title] Divergent myoid, neuroendocrine, and perineural differentiation in a nasal tumor of a patient with Carney complex.
  • Computed tomography showed bilateral thalamic infarctions and also an unsuspected multicompartmental cystic neoplasm that had eroded the anterior clivus and extended forward into the nasopharynx.
  • Histologically, the mass appeared benign and was composed of spindle cells and multiple foci of striated muscle.
  • [MeSH-major] Neoplasms, Muscle Tissue / ultrastructure. Neoplastic Syndromes, Hereditary / pathology. Nose Neoplasms / ultrastructure. Perineum / pathology


74. Xue Q, Wang H, Wang J: Recurrent respiratory papillomatosis: an overview. Eur J Clin Microbiol Infect Dis; 2010 Sep;29(9):1051-4
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  • Recurrent respiratory papillomatosis (RRP) primarily caused by human papillomas virus is a rare and benign neoplasm, primarily involving the epithelium mucosae of the respiratory tract.

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  • (PMID = 20517629.001).
  • [ISSN] 1435-4373
  • [Journal-full-title] European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
  • [ISO-abbreviation] Eur. J. Clin. Microbiol. Infect. Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
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75. Bhalla RK, Wright ED: Predicting the site of attachment of sinonasal inverted papilloma. Rhinology; 2009 Dec;47(4):345-8
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  • STATEMENT OF PROBLEM: Sinonasal inverted papilloma is a benign, epithelial neoplasm, which has a propensity for malignant transformation and recurrence.
  • The evolution of endoscopic trans-nasal surgery has facilitated less destructive and, more functionally and cosmetically acceptable approaches to this tumour.
  • [MeSH-major] Nose Neoplasms / epidemiology. Osteitis / epidemiology. Papilloma, Inverted / pathology

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  • (PMID = 19936356.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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76. Ooi BS, Quah HM, Fu CW, Eu KW: Laparoscopic high anterior resection with natural orifice specimen extraction (NOSE) for early rectal cancer. Tech Coloproctol; 2009 Mar;13(1):61-4
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  • [Title] Laparoscopic high anterior resection with natural orifice specimen extraction (NOSE) for early rectal cancer.
  • This procedure may be applicable to benign tumours and early colorectal cancer, and serves as an intermediate step between laparoscopic and natural orifice surgery.
  • [MeSH-minor] Anastomosis, Surgical. Colonoscopy. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 19288243.001).
  • [ISSN] 1128-045X
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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77. Shekarkhar MJ, Tabei SZ, Kumar PV, Hashemi SB: Cytologic findings in calcifying epithelial odontogenic tumor: a case report. Acta Cytol; 2005 Sep-Oct;49(5):533-6
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  • BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT), or Pindborg's tumor, is a rare, benign, odontogenic neoplasm first described by Pindborg in 1955.
  • CASE: A 62-year-old woman was referred to the ear, nose and throat clinic with a right maxillary mass.

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  • (PMID = 16334032.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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78. Saliba I, Evrard AS: Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. Cases J; 2009;2:6508
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  • Herein, we present a new case of a middle ear glandular neoplasm.
  • Our objective is to review all cases described in the literature in order to identify the clinical features, the gross pathology, the histopathology, the immunohistochemistry, to discuss the differential diagnosis, the treatment, the rate of recurrence, the follow-up, the incidence of metastasis, the prognosis and to present a new classification of middle ear glandular neoplasm.
  • CONCLUSIONS: Our study and the review of the literature showed adenomas and carcinoid tumors of the middle ear to be essentially indistinguishable benign tumors with metastatic potential.

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  • (PMID = 20111612.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2812983
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79. Vujevich JJ, Goldberg LH, Kimyai-Asadi A, Law R: Recurrent nodule on the nasal columella: a good reason to re-biopsy. Int J Dermatol; 2008 Jul;47(7):728-31
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  • [Title] Recurrent nodule on the nasal columella: a good reason to re-biopsy.
  • BACKGROUND: A 15-year-old Caucasian male presented with 9-month history of a recurrent nodule on the nasal columella.
  • METHODS: Frozen sections revealed a spindle cell neoplasm.
  • Re-biopsy of a "benign" growth may be necessary if clinicopathological correlation does not match with the clinical behavior of the tumor in question.
  • Finally, Mohs micrographic surgery is a useful treatment modality for leiomyosarcomas, particularly those located in cosmetically-sensitive regions of the body such as the nose.
  • [MeSH-major] Leiomyosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Neurofibroma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biopsy, Needle. Diagnosis, Differential. Follow-Up Studies. Frozen Sections. Humans. Immunohistochemistry. Male. Mohs Surgery / methods. Nasal Septum / pathology. Nasal Septum / surgery. Treatment Outcome

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  • (PMID = 18613884.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Spielmann PM, Adamson R, Cheng K, Sanderson RJ: Juvenile nasopharyngeal angiofibroma: spontaneous resolution. Ear Nose Throat J; 2008 Sep;87(9):521-3
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  • Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males.
  • We report the case of a 17-year-old male who presented in 1995 with a mass filling the left posterior nasal cavity.
  • [MeSH-minor] Adolescent. Biopsy, Needle. Humans. Immunohistochemistry. Magnetic Resonance Imaging / methods. Male. Nasal Obstruction / diagnosis. Nasal Obstruction / etiology. Neoplasm Staging. Remission, Spontaneous. Risk Assessment. Tomography, X-Ray Computed / methods

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  • (PMID = 18800325.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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81. Otoh EC, Johnson NW, Olasoji H, Danfillo IS, Adeleke OA: Salivary gland neoplasms in Maiduguri, north-eastern Nigeria. Oral Dis; 2005 Nov;11(6):386-91
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  • OBJECTIVE: To document the pattern of salivary gland neoplasia in Maiduguri, Nigeria.
  • RESULTS: The palatal (71.9%) and parotid (78.3%) glands were the most common minor and major salivary glands involved, with a benign-malignant ratio of 1:1 and 1.4:1, respectively.
  • Pleomorphic adenoma (44.3%) was the most common salivary gland neoplasm recorded.
  • Ectopic lesions (17.1%) were reported in the neck, nose and cervical nodes.
  • CONCLUSION: Pleomorphic adenoma and mucoepidermoid carcinoma were the most commonly reported benign and malignant neoplasia in this series.

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  • (PMID = 16269031.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Denmark
  • [Number-of-references] 30
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82. Ethmoidal osteoid osteoma with orbital and intracranial extension - a case report. BMC Ear Nose Throat Disord; 2005 Mar 11;5:2
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  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton.
  • CONCLUSION: Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures.

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  • (PMID = 15760476.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC555567
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83. Gupta R, Khurana N, Singh DK, Singh S: Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):447-8
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  • [Title] Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm.
  • [MeSH-major] Nasal Cavity / pathology. Neurilemmoma / diagnosis. Neurilemmoma / pathology. Nose Neoplasms / diagnosis. Nose Neoplasms / pathology

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  • (PMID = 18723990.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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84. Kaptanoglu AF, Kutluay L: Keratoacanthoma developing in previous cryotherapy site for solar keratosis. J Eur Acad Dermatol Venereol; 2006 Feb;20(2):197-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Keratoacanthoma is a relatively common benign squamous neoplasm that may show spontaneous clearing.
  • [MeSH-minor] Cicatrix / pathology. Diagnosis, Differential. Humans. Keratosis / surgery. Male. Middle Aged. Nose / pathology. Sunlight

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  • (PMID = 16441631.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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86. Ayers LS, Depasquale K, Marlowe FI, Ghaderi M: Pleomorphic adenoma of the external auditory canal: a case report and review of the literature. Ear Nose Throat J; 2010 Mar;89(3):E1-3
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  • Pleomorphic adenomas of the external auditory canal (EAC) are benign tumors of the ceruminal glands; they are a rare entity.
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Invasiveness

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  • (PMID = 20229463.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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87. Scurry WC Jr, McGinn JD: Recurrent respiratory papillomatosis in pregnancy: a case of emergent airway management. Ear Nose Throat J; 2008 Jun;87(6):E8-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Recurrent respiratory papillomatosis is a benign neoplastic process involving squamous epithelium of the respiratory tract, typically the vocal folds.
  • [MeSH-major] Laryngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Papilloma / surgery. Pregnancy Complications, Neoplastic / surgery. Pregnancy Outcome


88. Joo D, Chhetri DK, Wang MB: Endoscopic removal of juvenile nasopharyngeal angiofibromas: a video presentation. Laryngoscope; 2008 Jun;118(6):e1-3
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  • OBJECTIVES/HYPOTHESIS: Juvenile nasal angiogibroma (JNA) is a relatively rare, benign neoplasm generally seen in prepubertal and adolescent males.
  • Our presentation demonstrates an endoscopic approach to excision of JNAs that are limited to the nasal cavity, nasopharynx, and paranasal sinuses.
  • [MeSH-major] Angiofibroma / surgery. Endoscopy / methods. Nasal Cavity. Nasopharyngeal Neoplasms / surgery. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18391769.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Percodani J, Rose X, Vergez S, Pessey JJ, Serrano E: [Endonasal endoscopic approach in the treatment of sino-nasal inverted papillomas]. Ann Otolaryngol Chir Cervicofac; 2006 Dec;123(6):312-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endonasal endoscopic approach in the treatment of sino-nasal inverted papillomas].
  • [Transliterated title] Voie endonasale endoscopique dans le traitement des papillomes inversés naso-sinusiens.
  • INTRODUCTION: Sino-nasal inverted papilloma is a rare benign tumor of the nasal fossa and the paranasal sinuses for which the successful surgical treatment by an endonasal approach has been corroborated in the literature.
  • MATERIAL AND METHODS: 42 patients presenting with a sino-nasal inverted papilloma and treated surgically over a ten year period were included in this retrospective study.
  • Fourteen patients were operated using a combined approach, associating either a vestibular (9 cases), a paralateral nasal (3 cases) or a fronto-orbital (2 cases) approach with endonsal endoscopy.
  • CONCLUSIONS: Endoscopic endonasal surgery is a validated surgical approach for the treatment of sino-nasal inverted papilloma in that total tumor removal is possible.
  • [MeSH-major] Endoscopy / methods. Ethmoid Sinus. Frontal Sinus. Maxillary Sinus Neoplasms / surgery. Nose Neoplasms / surgery. Papilloma, Inverted / surgery. Paranasal Sinus Neoplasms / surgery. Sphenoid Sinus
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors

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  • (PMID = 17202989.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] France
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90. Wang WH, Lee SS, Wang LF, Lai CS: Repair oronasal fistula in a treated juvenile nasopharyngeal angiofibroma patient. J Plast Reconstr Aesthet Surg; 2007;60(10):1148-51
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  • OBJECTIVE: The juvenile nasopharyngeal angiofibroma (JNA) is a benign neoplasm that affects mostly young males.
  • [MeSH-major] Angiofibroma / surgery. Fistula / surgery. Nasopharyngeal Neoplasms / surgery. Nose Diseases / surgery. Oral Fistula / surgery

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  • (PMID = 17825778.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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91. Tasca RA, Clarke RW: Recurrent respiratory papillomatosis. Arch Dis Child; 2006 Aug;91(8):689-91
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  • Recurrent respiratory papillomatosis (RRP) is a benign, often multi-focal neoplasm.
  • [MeSH-major] Neoplasm Recurrence, Local. Papilloma. Papillomavirus Infections. Respiratory Tract Neoplasms

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  • (PMID = 16861486.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antiviral Agents
  • [Number-of-references] 31
  • [Other-IDs] NLM/ PMC2083023
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92. Jezewska E, Tulibacki M, Tomaszewska M, Nowaczewska K, Oledzka I, Kukwa A: [Removing illness changes related with ORL in laser-clinic in 2005]. Otolaryngol Pol; 2007;61(1):25-8
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  • There are 47 cases presented in article (28 women and 19 men) from who pieces of nasal cavity, oral cavity or throat were taken or illness changes have been curing.
  • Group No 1 containing 11 men and 10 women with removing changes in nasal cavity.
  • RESULTS: Among majority patients removed pices were proliferation of neoplasm - benign type (20 patients).
  • In 2 cases were papilloma and 4 causes were malignant neoplasm.
  • 8 patients had chronic state with metaplasia and displasia within nose.
  • Control visits did not show the increase of illness (except malignant neoplasm).
  • CONCLUSIONS: Laser ND-YAG may be used to remove egzofitical changes and to take some pices in case of neoplasm.
  • Using laser technology high precision is possible and deep penetration of laser make the operations safer in case of neoplasm.

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  • (PMID = 17605414.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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93. Yaşar H, Ozkul H, Verim A, Ilhan E, Kökten N, Dereci G: [An evaluation of parotid gland masses]. Kulak Burun Bogaz Ihtis Derg; 2007;17(2):70-4
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  • Histopathological diagnoses were benign in 33 patients (66%), malignant in nine patients (18%), and tumor-like pathologies in eight patients (16%), the most common being pleomorphic adenoma (n=28, 56%), Warthin's tumor (n=4, 8%), and squamous cell carcinoma (n=4, 8%).
  • [MeSH-major] Neoplasm Recurrence, Local / epidemiology. Parotid Diseases / epidemiology

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  • (PMID = 17527056.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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94. Eloy P, Watelet JB, Hatert AS, de Wispelaere J, Bertrand B: Endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma. Rhinology; 2007 Mar;45(1):24-30
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  • Juvenile angiofibroma (JNA) is a rare benign but locally aggressive tumour of the nasopharynx that primarily occurs in adolescent males.
  • [MeSH-minor] Adolescent. Adult. Blood Loss, Surgical. Child. Embolization, Therapeutic. Follow-Up Studies. Humans. Male. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / surgery. Palate / surgery. Paranasal Sinus Neoplasms / surgery. Reoperation. Skull Base Neoplasms / surgery. Sphenoid Bone / surgery. Sphenoid Sinus / surgery. Time Factors

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  • (PMID = 17432065.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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95. Pata YS, Akbaş Y, Unal M, Tataroğlu C: A case of intranasal schwannoma with bilateral nasal polyposis. Kulak Burun Bogaz Ihtis Derg; 2005;15(1-2):45-8
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  • [Title] A case of intranasal schwannoma with bilateral nasal polyposis.
  • Schwannoma is a benign neoplasm originating from schwann cells of the peripheral nerve sheath, and its occurrence in the nasal cavity and paranasal sinuses is rare.
  • We present a case of nasal schwannoma originating from the left nasal cavity, accompanied by bilateral nasal polyposis.
  • A 66-year-old man presented with complaints of progressive left nasal obstruction, hyposmia, and headache.
  • Anterior rhinoscopic and endoscopic examinations revealed a mass that almost completely filled the left nasal cavity.
  • A polypoid mass was present in the right nasal cavity, as well.
  • On computed tomography, the mass occupied the left ethmoidal cells, left maxillary sinus, left sphenoid sinus, and posterior area of the left nasal cavity.
  • Endoscopic anterior ethmoidectomy was also performed in the right nasal cavity for nasal polyposis.
  • Histopathological diagnosis of the left nasal mass was schwannoma.
  • [MeSH-major] Nasal Polyps / diagnosis. Neurilemmoma / diagnosis. Nose Neoplasms / diagnosis

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  • (PMID = 16340292.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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96. Saetti R, Silvestrini M, Narne S: Ethmoid osteoma with frontal and orbital extension: endoscopic removal and reconstruction. Acta Otolaryngol; 2005 Oct;125(10):1122-5
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  • Endoscopy provides a safe and effective way of treating craniofacial bony benign lesions.
  • It is the most frequent benign neoplasm of the nose and paranasal sinuses.
  • We report the case of a bulky fronto-ethmo-orbital osteoma that was treated using an endoscopic trans-nasal approach.
  • [MeSH-minor] Adult. Endoscopy. Female. Frontal Bone / pathology. Frontal Bone / surgery. Humans. Neoplasm Invasiveness. Orbit / pathology. Orbit / surgery. Reconstructive Surgical Procedures

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  • (PMID = 16298798.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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97. Fei Z, Zhang X, Jiang XF, Liu WP, Wang XL, Xie L: Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation. J Craniomaxillofac Surg; 2007 Jan;35(1):30-4
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  • [Title] Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation.
  • The tumours were located in the anterior or middle skull base, the paranasal sinus, and/or the nasal cavity.
  • CONCLUSION: Transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation is a particularly useful technique for resecting large benign cephalonasal tumours.
  • [MeSH-minor] Abducens Nerve Diseases / etiology. Adolescent. Adult. Child. Child, Preschool. Deglutition Disorders / etiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nasal Cavity / surgery. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / pathology. Nose Neoplasms / surgery. Olfaction Disorders / etiology. Ophthalmoplegia / etiology. Paralysis / etiology. Paranasal Sinus Neoplasms / surgery. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Skull Base Neoplasms / surgery

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  • (PMID = 17261369.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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98. Mendenhall WM, Olivier KR, Lynch JW Jr, Mendenhall NP: Lethal midline granuloma-nasal natural killer/T-cell lymphoma. Am J Clin Oncol; 2006 Apr;29(2):202-6
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  • [Title] Lethal midline granuloma-nasal natural killer/T-cell lymphoma.
  • PURPOSE: The purpose of this paper is to discuss lethal midline granuloma (LMG)-nasal natural killer (NK) T-cell lymphoma (LMG-NTL).
  • RESULTS: LMG is a rare entity that usually arises in the nasal cavity, exhibits a male preponderance, and has a wide age range.
  • CONCLUSIONS: LMG-NTL is a rare nasal NK/T-cell lymphoma that can be difficult to distinguish from other benign and malignant entities.
  • [MeSH-major] Granuloma, Lethal Midline / pathology. Lymphoma, T-Cell / pathology. Nose Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Killer Cells, Natural. Neoplasm Staging. Prognosis. Sex Factors. Survival Analysis


99. Bignami M, Dallan I, Battaglia P, Lenzi R, Pistochini A, Castelnuovo P: Endoscopic, endonasal management of sinonasal haemangiopericytoma: 12-year experience. J Laryngol Otol; 2010 Nov;124(11):1178-82
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  • MATERIALS AND METHODS: Retrospective review of the medical records of 10 patients undergoing endoscopic, endonasal surgery for sinonasal haemangiopericytoma of the nose and paranasal sinuses, between 1997 and 2008.
  • CONCLUSIONS: Sinonasal haemangiopericytomas are rare tumours that are usually benign.
  • [MeSH-major] Endoscopy / methods. Hemangiopericytoma / surgery. Neoplasm Recurrence, Local / surgery. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Length of Stay. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging. Reoperation. Retrospective Studies. Treatment Outcome

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  • (PMID = 20438660.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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100. Sabir Husin Athar PP, Yahya Z, Mat Baki M, Abdullah A: Facial nerve paralysis: a rare complication of parotid abscess. Malays J Med Sci; 2009 Apr;16(2):38-9
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  • Benign parotid neoplasm and inflammatory processes of the parotid resulting in facial paralysis are extremely rare.

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  • (PMID = 22589657.001).
  • [ISSN] 1394-195X
  • [Journal-full-title] The Malaysian journal of medical sciences : MJMS
  • [ISO-abbreviation] Malays J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Other-IDs] NLM/ PMC3336167
  • [Keywords] NOTNLM ; facial nerve injuries / neurosciences / parotid neoplasms / parotitis
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