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1. Okuno M, Kawashima M, Miura K, Kadota E, Goto S, Kato M: Resection of giant mediastinal liposarcoma using the hemiclamshell incision. Gen Thorac Cardiovasc Surg; 2010 Dec;58(12):654-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resection of giant mediastinal liposarcoma using the hemiclamshell incision.
  • A computed tomography scan revealed a large well-defined mass in close relationship to the great vessels of the anterior mediastinum.
  • Magnetic resonance imaging showed the anterior mediastinal mass, which was about 25 cm in diameter, expanding to the left pleural cavity with heterogeneous intensity.
  • Because of the size and location of the mass, a combination of anterolateral thoracotomy and partial longitudinal median sternotomy--so-called hemiclamshell incision--was chosen, allowing excellent visualization and complete dissection of the giant tumor.
  • [MeSH-major] Liposarcoma / surgery. Mediastinal Neoplasms / surgery. Sternotomy. Thoracotomy

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  • (PMID = 21170639.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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2. Płachcińska A, Mikołajczak R, Kozak J, Rzeszutek K, Kuśmierek J: Comparative analysis of 99mTc-depreotide and 99mTc-EDDA/HYNIC-TOC thorax scintigrams acquired for the purpose of differential diagnosis of solitary pulmonary nodules. Nucl Med Rev Cent East Eur; 2006;9(1):24-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative analysis of 99mTc-depreotide and 99mTc-EDDA/HYNIC-TOC thorax scintigrams acquired for the purpose of differential diagnosis of solitary pulmonary nodules.
  • BACKGROUND: Aiming at comparison of diagnostic efficacy of 2 radiopharmaceuticals: 99mTc-depreotide (Neospect, Amersham) and 99mTc-EDDA/HYNIC-Tyr3-octreotide (Tektrotyd, Polatom), in differentiation between malignant and benign etiology of solitary pulmonary nodules (SPNs), radionuclide studies with 2 radiotracers were performed in 18 patients.
  • Additionally, uptake intensity of both radiotracers in nodules was assessed semiquantitatively, using a tumour-to-background ratio.
  • Verification of scintigraphic results was based in 14 cases upon a pathological examination of tumour samples (histopathology) and in the remaining 4 - on clinical observation and bacteriological studies.
  • In 6 patients a malignant etiology--lung cancer--was revealed (5--adenocarcinoma, 1--squamous cell) and the other 12 cases turned out to be benign (4 hamartomas, 3 tuberculomas, a tuberculous infiltrate, an alien body with inflammatory reaction, a hyperplasia of lymphatic tissue and 2 cases of unknown etiology, from which one had a stable size and the other resolved during a 6 month observation period).
  • Moreover, in 2 patients metastases in mediastinum could be observed on scintigrams obtained with both radiopharmaceuticals.
  • From among 12 cases of benign etiology 6 99mTc-depreotide scintigrams were true negative, 1--equivocal and 5--false positive, whereas 6 99mTc-EDDA/HYNIC-TOC scintigrams were true negative, 4--equivocal and 2 false positive.
  • Moreover, 99mTc-depreotide additionally revealed mediastinal and hilar lesions in 9 patients with benign lesions and 99mTc-EDDA/HYNIC-TOC - in 8.
  • However, mean values of tumour-to-lung-background ratio were equal for both radiotracers (2.2 in malignant and 1.4 in benign lesions, respectively).
  • A substantial number of false positive lesions in mediastinal and hilar regions in patients without a neoplastic process hamper the usefulness of both radiotracers for effective detection of lung cancer metastases to lymph nodes.
  • [MeSH-major] Edetic Acid / analogs & derivatives. Octreotide / analogs & derivatives. Organotechnetium Compounds. Radiopharmaceuticals. Solitary Pulmonary Nodule / diagnosis. Solitary Pulmonary Nodule / radionuclide imaging. Somatostatin / analogs & derivatives. Thorax / radionuclide imaging
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Radionuclide Imaging / methods

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  • (PMID = 16791800.001).
  • [ISSN] 1506-9680
  • [Journal-full-title] Nuclear medicine review. Central & Eastern Europe
  • [ISO-abbreviation] Nucl Med Rev Cent East Eur
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 0 / technetium Tc 99m hydrazinonicotinyl-Tyr(3)-octreotide; 51110-01-1 / Somatostatin; 5657-17-0 / EDDA; 9G34HU7RV0 / Edetic Acid; 9M48M2SF02 / technetium Tc 99m depreotide; RWM8CCW8GP / Octreotide
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3. Idress MT, Reid-Nicholson M, Unger P, Jaffer S: Subhepatic ciliated foregut cyst. Ann Diagn Pathol; 2005 Feb;9(1):54-6
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  • Foregut cyst derives from the primitive foregut and occurs in the tracheobronchial tree, mediastinum, liver, pancreas, tongue, and upper digestive tract.

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  • (PMID = 15692953.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Mucin-1; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / Vimentin; 0 / thyroid nuclear factor 1; 68238-35-7 / Keratins
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4. Schützner J, Tvrdon J, Lischke R, Smat V, Pafko P: [Our strategy in the therapy of myasthenia gravis]. Zentralbl Chir; 2005 Apr;130(2):114-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thymectomy combined with exenteration of fatty tissue from the front mediastinum belongs to basic MG surgery.
  • [MeSH-major] Myasthenia Gravis / surgery. Thymectomy. Thymoma / surgery. Thymus Neoplasms / surgery


5. Daskalakis G, Anastasakis E, Souka A, Manoli A, Koumpis C, Antsaklis A: First trimester ultrasound diagnosis of congenital diaphragmatic hernia. J Obstet Gynaecol Res; 2007 Dec;33(6):870-2
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  • [Title] First trimester ultrasound diagnosis of congenital diaphragmatic hernia.
  • We present here a case of left-sided diaphragmatic hernia diagnosed at 12 weeks of gestation and a short review of published reports on first trimester diagnosis of this defect.
  • Ultrasound diagnosis of congenital diaphragmatic hernia cases, with early herniation of the viscera in the thorax, is feasible during the first trimester.
  • Hallmarks of the diagnosis, in the first trimester as well as later in pregnancy, are the presence of the stomach, bowel or liver in the chest, and the shift of the mediastinum.
  • Early diagnosis of this defect is essential.


6. Bergmann T, Bölükbas S, Beqiri S, Schirren J: [Video-assisted diagnostic thoracoscopy]. Chirurg; 2006 Nov;77(11):998-1006
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Modern radiologic diagnostics show a variety of pathological changes in the mediastinum, pleura, and lung but no evidence on their histogenesis.
  • Video-assisted thoracoscopy allows safe and fast diagnosis of diffuse lung diseases, pleural diseases including malignant mesothelioma, indeterminate peripheral lung nodule, and mediastinal masses.
  • [MeSH-major] Lung Neoplasms / diagnosis. Mesothelioma / diagnosis. Pleural Effusion / etiology. Pleural Neoplasms / diagnosis. Pulmonary Fibrosis / diagnosis. Solitary Pulmonary Nodule / diagnosis. Thoracic Surgery, Video-Assisted / methods
  • [MeSH-minor] Diagnosis, Differential. Humans. Lung / pathology. Neoplasm Staging. Pleura / pathology

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  • (PMID = 17075713.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 39
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7. Steger C, Steiner HJ, Moser K, Fiechtl H, Moser P, Schmid T, Rieker RJ: A typical thymic carcinoid tumour within a thymolipoma: report of a case and review of combined tumours of the thymus. BMJ Case Rep; 2010;2010
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  • [Title] A typical thymic carcinoid tumour within a thymolipoma: report of a case and review of combined tumours of the thymus.
  • Thymolipomas are rare tumours located in the anterior mediastinum.
  • The following CT scan of the neck and chest showed a small tumour in the anterior mediastinum.
  • A robotic-assisted thymectomy was performed and histological examination revealed a neuroendocrine tumour of the thymus within a thymolipoma.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Lipoma / diagnosis. Neoplasms, Complex and Mixed / diagnosis. Thymus Neoplasms / diagnosis

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  • (PMID = 22791779.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028107
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8. Nicksa GA, Pigula FA, Giuffrida MJ, Buchmiller TL: Removal of a sewing needle from an occult esophageal ingestion in a 9-month-old. J Pediatr Surg; 2009 Jul;44(7):1450-3
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  • A chest x-ray showed a linear metallic foreign body (FB) lying transversely in the posterior mediastinum.
  • The patient underwent a right thoracotomy revealing a normal esophagus without mediastinitis and a 12-mm needle in the posterior mediastinum embedded in the pericardium with the sharp end abutting the left atrium.
  • The diagnosis and treatment for this case are discussed along with a review of the literature.
  • [MeSH-minor] Diagnosis, Differential. Eating. Humans. Infant. Male. Radiography, Thoracic. Tomography, X-Ray Computed

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  • (PMID = 19573678.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Kaira K, Endo M, Asakura K, Tsuya A, Nakamura Y, Naito T, Murakami H, Takahashi T, Yamamoto N: Ratio of standardized uptake value on PET helps predict response and outcome after chemotherapy in advanced non-small cell lung cancer. Ann Nucl Med; 2010 Dec;24(10):697-705
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The maximum standardized uptake value (SUV(max)) on (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET) within the primary tumor may predict outcome in patients with surgically resected non-small cell lung cancer (NSCLC).
  • However, it remains uncertain whether the SUV(max) of the primary tumor predicts outcome after chemotherapy in advanced NSCLC.
  • Thus, we evaluated the ratio of SUV(max) of the metastatic tumor to the primary tumor (M/P ratio) to determine whether it could be a useful marker in predicting response and outcome after chemotherapy in advanced NSCLC.
  • Response and survival were analyzed according to the SUV(max) of primary tumor, the ratio of the SUV(max) of the tumor to the mean SUV of the mediastinum (T/M ratio) and M/P ratio.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / drug therapy. Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Lung Neoplasms / drug therapy. Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biological Transport. Female. Fluorodeoxyglucose F18 / metabolism. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Metastasis. Neoplasm Staging. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 20824397.001).
  • [ISSN] 1864-6433
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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10. Varlotto JM, Recht A, Flickinger JC, Medford-Davis LN, Dyer AM, DeCamp MM: Varying recurrence rates and risk factors associated with different definitions of local recurrence in patients with surgically resected, stage I nonsmall cell lung cancer. Cancer; 2010 May 15;116(10):2390-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Local recurrence was defined either as 'radiation' (r-LR) (according to previously defined postoperative radiotherapy fields), including the bronchial stump, staple line, ipsilateral hilum, and ipsilateral mediastinum; or as 'comprehensive' (c-LR), including the same sites plus the ipsilateral lung and contralateral mediastinal and hilar lymph nodes.
  • Significant risk factors for c-LR on multivariate analysis were diabetes, lymphatic vascular invasion, and tumor size; and significant factors for r-LR were resection of less than a lobe and lymphatic vascular invasion.
  • Significant risk factors for distant failure were histology when using the c-LR definition and tumor size when using the r-LR definition.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / pathology. Lung Neoplasms / pathology. Neoplasm Recurrence, Local

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  • [Copyright] (c) 2010 American Cancer Society.
  • (PMID = 20225332.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Lu JC, Tao H, Zhang YQ, Zha WW, Qian PD, Li F, Xu KX: Extent of prophylactic postoperative radiotherapy after radical surgery of thoracic esophageal squamous cell carcinoma. Dis Esophagus; 2008;21(6):502-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SUMMARY: The aim of this study was to assess if the entire mediastinum (M), the bilateral supraclavicular area (S), and the left gastric area (L) should be all included in the irradiation volume.

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  • (PMID = 18840135.001).
  • [ISSN] 1442-2050
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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12. Laín A, Parente A, Cañiizo A, Fanjul M, García-Casillas MA, Matute JA, Vázquez J: [Modified "trap-door" thoracotomy for pediatric patients]. Cir Pediatr; 2008 Apr;21(2):111-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Toracotomía de "trap-door" modificada en pacientes pediátricos.
  • CONCLUSION. The modified "Trap-door" approach allows a good control of the brachiocephalic structures and a complete visualization of the upper thorax and posterior mediastinum.
  • [MeSH-minor] Child, Preschool. Cricoid Cartilage / abnormalities. Cricoid Cartilage / surgery. Esophagus / abnormalities. Esophagus / surgery. Female. Head and Neck Neoplasms / surgery. Humans. Infant. Infant, Newborn. Male. Retrospective Studies. Scoliosis / surgery. Thoracic Neoplasms / surgery

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  • (PMID = 18624282.001).
  • [ISSN] 0214-1221
  • [Journal-full-title] Cirugía pediátrica : organo oficial de la Sociedad Española de Cirugía Pediátrica
  • [ISO-abbreviation] Cir Pediatr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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13. Msaad S, Fouzi S, Ketata W, Ayedi L, Abdennadher M, Makni S, Yaich O, Abid T, Ayoub A: [An anterior mediastinal mass of rare etiology]. Rev Mal Respir; 2009 Mar;26(3):324-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An anterior mediastinal mass of rare etiology].
  • Hydatid cyst of the mediastinum is very uncommon.
  • The diagnosis, usually evident in endemic regions in the case of a typical clinical-radiological presentation, is rather more difficult in certain atypical forms.
  • We report a case of a 19-year-old man who presented with a mass of tumour like appearance in the anterior mediastinum.
  • The diagnosis of mediastinal hydatid cyst was established by transthoracic needle biopsy and endoscopic bronchial aspiration revealed hydatid membranous debris.
  • The diagnosis was confirmed when the mediastinal cyst ruptured into a bronchus.
  • This observation illustrates the diagnostic difficulties when a mediastinal hydatid cyst presents the appearances of a tumour.
  • This possibility must be included in the differential diagnosis of every mediastinal mass, particularly in endemic regions.
  • [MeSH-major] Echinococcosis / diagnosis. Mediastinal Diseases / diagnosis. Mediastinal Diseases / parasitology

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  • (PMID = 19367207.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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14. Watts KA, Watts JR Jr: Incidental discovery of an anterior mediastinal angiomyolipoma. J Thorac Imaging; 2007 May;22(2):180-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidental discovery of an anterior mediastinal angiomyolipoma.
  • Angiomyolipomas are benign mesenchymal tumors consisting of blood vessels, smooth muscle, and fat.
  • These noninvasive lesions characteristically manifest in renal tissue but may arise less frequently in extrarenal locations including the mediastinum.
  • Only 8 cases of mediastinal angiomyolipomas have been reported in the literature, 3 of which were reported in the English literature, and only 2 of which were located in the anterior mediastinum.
  • We report a surgically confirmed case of an anterior mediastinal angiomyolipoma incidentally discovered in an asymptomatic patient, in whom a screening breast magnetic resonance imaging revealed an incidental 5.7 cm anterior mediastinal mass.
  • Further characterization with contrast-enhanced chest computed tomography confirmed a heterogeneously enhancing anterior mediastinal mass, suggestive of thymoma or lymphoma.
  • [MeSH-major] Angiomyolipoma / diagnosis. Incidental Findings. Lymphoma / diagnosis. Mediastinal Neoplasms / diagnosis. Thymoma / diagnosis. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Contrast Media / administration & dosage. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging / methods. Mediastinum / pathology. Mediastinum / radiography. Middle Aged. Radiographic Image Enhancement / methods. Radiography, Thoracic / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 17527125.001).
  • [ISSN] 0883-5993
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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15. Mu JW, Xing XZ, Li J, Cheng GY, Sun KL, He J: [Primary soft tissue sarcomas of mediastinum: experience in 22 cases from a single institution]. Zhonghua Yi Xue Za Zhi; 2008 Feb 19;88(7):468-70
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  • [Title] [Primary soft tissue sarcomas of mediastinum: experience in 22 cases from a single institution].
  • OBJECTIVE: To assess the presentation, imaging features, and prognostic factors of primary soft tissue sarcoma of mediastinum.
  • METHODS: The clinical data of 22 patients with primary soft tissue sarcoma of mediastinum, 12 males and 10 females, aged 46 (28-69), hospitalized over 27 years were retrospectively reviewed, focusing on the clinical presentations, preoperative diagnosis, imaging features, immunohistochemical studies, treatment, and survival.
  • CONCLUSION: Tumor size and character of resection are important prognostic factors for primary soft tissue sarcoma of mediastinum.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Sarcoma / surgery
  • [MeSH-minor] Adult. Aged. Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Mediastinum / pathology. Mediastinum / surgery. Middle Aged. Retrospective Studies. Survival Analysis. Vimentin / analysis

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  • (PMID = 18642788.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Vimentin
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16. von Falck C, Boerner AR, Galanski M, Knapp WH: Neuroendocrine tumour of the mediastinum: fusion of 18F-FDG and 68Ga-DOTATOC PET/CT datasets demonstrates different degrees of differentiation. Eur J Nucl Med Mol Imaging; 2007 May;34(5):812
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  • [Title] Neuroendocrine tumour of the mediastinum: fusion of 18F-FDG and 68Ga-DOTATOC PET/CT datasets demonstrates different degrees of differentiation.
  • [MeSH-major] Fluorodeoxyglucose F18. Gallium Radioisotopes. Mediastinal Neoplasms / diagnostic imaging. Neuroendocrine Tumors / diagnostic imaging. Octreotide / analogs & derivatives. Organometallic Compounds. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • [Cites] J Nucl Med. 2005 Jan;46 Suppl 1:172S-8S [15653666.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2006 Oct;33(10 ):1115-22 [16763820.001]
  • [Cites] Eur J Nucl Med. 1998 Jan;25(1):79-83 [9396878.001]
  • (PMID = 17242919.001).
  • [ISSN] 1619-7070
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ga(III)-DOTATOC; 0 / Gallium Radioisotopes; 0 / Organometallic Compounds; 0Z5B2CJX4D / Fluorodeoxyglucose F18; RWM8CCW8GP / Octreotide
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17. Herth FJ, Ernst A, Eberhardt R: Restaging of the mediastinum. Curr Opin Pulm Med; 2009 Jul;15(4):308-12
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  • [Title] Restaging of the mediastinum.
  • RECENT FINDINGS: The question, how to reassess patients with stage IIIA non-small-cell lung cancer after neoadjuvant therapy, is broader than just looking at downstaging of mediastinal lymph nodes, but also involves prediction of partial or complete pathologic response on the primary tumor and long-term outcome prediction.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / pathology. Lung Neoplasms / pathology. Mediastinum / pathology
  • [MeSH-minor] Algorithms. Humans. Lymph Nodes / pathology. Neoadjuvant Therapy. Neoplasm Staging / methods

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  • (PMID = 19436205.001).
  • [ISSN] 1531-6971
  • [Journal-full-title] Current opinion in pulmonary medicine
  • [ISO-abbreviation] Curr Opin Pulm Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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18. Liu L, Mei J, Che G: Asymptomatic paraganglioma of the posterior mediastinum misdiagnosed until operation. Thorac Cardiovasc Surg; 2010 Aug;58(5):302-4
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  • [Title] Asymptomatic paraganglioma of the posterior mediastinum misdiagnosed until operation.
  • A 23-year-old female patient was treated for a posterior mediastinal tumor of unknown histology.
  • Her systemic blood pressure increased rapidly to a critical level immediately after starting surgical manipulation of the tumor, which was suggestive of a hyperfunctioning pheochromocytoma.
  • The tumor was removed after controlling the blood pressure and was histologically diagnosed as an extra-adrenal pheochromocytoma.
  • Further postoperative investigations showed the tumor to be a sporadic type through further postoperative investigations and the patient had subsequently an uneventful course.
  • [MeSH-major] Diagnostic Errors. Mediastinal Neoplasms / diagnosis. Paraganglioma, Extra-Adrenal / diagnosis. Thoracotomy

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  • [Copyright] Copyright (c) Georg Thieme Verlag KG Stuttgart-New York.
  • (PMID = 20680909.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antihypertensive Agents
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19. Kuwata T, Inadome A, Matsumoto K, Yoshida M, Ueda S: [Case report of calcifying fibrous pseudotumor of the adrenal grand]. Nihon Hinyokika Gakkai Zasshi; 2008 Jan;99(1):48-51
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  • Calcifying fibrous (pseudo) tumour (CFP) is an uncommon and distinct pathological entity, which is usually occurring in the soft tissue of the extremities, trunk, axilla, pleura, mediastinum and peritoneum.
  • Pathological findings of the left adrenal tumor showed dense hyalinized fibrous tissue containing bland spindle-shaped cells, calcifications, and lymphoplasmacytic infiltrate.
  • [MeSH-major] Adrenal Gland Neoplasms / surgery. Calcinosis / surgery. Granuloma, Plasma Cell / surgery. Neoplasms, Muscle Tissue / surgery

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  • (PMID = 18260349.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 13
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20. Thibodeau MP, Brigand C, Ferraro P, Martin J, Duranceau A: Esophagectomy for complications of esophageal intramural pseudodiverticulosis. Dis Esophagus; 2007;20(2):178-82
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  • The condition led to fistulization and abscess formation in the mediastinum.

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  • (PMID = 17439604.001).
  • [ISSN] 1120-8694
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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21. Ganti S, Milton R, Davidson L, Anikin V: Giant pulmonary hamartoma. J Cardiothorac Surg; 2006;1:19
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  • The tumour was arising from the medial border of the right lung and occupying most of the right chest extending in to the anterior mediastinum.
  • The tumour was compressing the right lung and there was no evidence of infiltration into the surrounding structures.
  • [MeSH-major] Hamartoma. Lung Neoplasms

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  • [Cites] Thorax. 1987 Oct;42(10):790-3 [3321538.001]
  • [Cites] Chest. 2002 Jul;122(1):202-5 [12114359.001]
  • [Cites] Chest. 1976 Sep;70(03):332-6 [954458.001]
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  • (PMID = 16887035.001).
  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1552053
  • [General-notes] NLM/ Original DateCompleted: 20070719
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22. Brearley WD Jr, Taylor L 3rd, Haley MW, Littmann L: Pneumomediastinum mimicking acute ST-segment elevation myocardial infarction. Int J Cardiol; 2007 Apr 25;117(2):e73-5
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  • Pneumomediastinum is characterized by dissecting air within the connective tissues supporting the mediastinum.
  • [MeSH-major] Electrocardiography. Mediastinal Emphysema / diagnosis. Myocardial Infarction / diagnosis
  • [MeSH-minor] Artifacts. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 17320223.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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23. Pegov RG, Aliasova AV, Novikov VV, Baryshnikov AIu: [The serum levels of a soluble form of HLA I molecules in patients with lung cancer]. Klin Lab Diagn; 2009 Feb;(2):38-40
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  • The serum concentration of sHLA-I molecules is decreased when the involvement foci are located in the lymph nodes of the lung root or in the mediastinum, but significantly increased when distant metastases emerge.
  • The different morphological variants of the structure of a tumor do not differ in the serum content of sHLA molecules in the patients.
  • [MeSH-major] HLA Antigens / blood. Lung Neoplasms / blood
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging / methods

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  • (PMID = 19338089.001).
  • [ISSN] 0869-2084
  • [Journal-full-title] Klinicheskaia laboratornaia diagnostika
  • [ISO-abbreviation] Klin. Lab. Diagn.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / HLA Antigens
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24. Orellana F, Cárdenas R, Manríquez ME, Ríos H, Suárez L, Videla D: [Retroperitoneal bronchogenic cyst: Report of one case]. Rev Med Chil; 2007 Jul;135(7):924-31
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  • Benign lesions include lipomas and leiomyomas, among others.
  • Bronchogenic cysts are congenital anomalies that result from an abnormal budding of the primitive foregut, and are most commonly found in the mediastinum.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Laparoscopy. Pancreatectomy / methods

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  • (PMID = 17914551.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
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25. Tanaka H, Sasayama T, Nishihara M, Arai A, Kawamura A, Kanomata N, Itoh T, Kohmura E: Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report. Neurol Med Chir (Tokyo); 2010;50(8):689-93
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  • Magnetic resonance (MR) imaging demonstrated multiple tumors in the brain, subcutaneous soft tissue, and mediastinum.
  • The histological diagnosis was undifferentiated high-grade sarcoma.
  • Promoter hypermethylation in the O(6)-methylguanine-deoxyribonucleic acid methyltransferase (MGMT) genes was detected and MGMT protein expression was negative in the recurrent tumor, so temozolomide (TMZ) salvage chemotherapy was given, and follow-up MR imaging showed tumor reduction.
  • [MeSH-major] Antineoplastic Agents, Alkylating / therapeutic use. Brain Neoplasms / therapy. Dacarbazine / analogs & derivatives. Neoplasm Recurrence, Local / therapy. Sarcoma / therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. DNA Modification Methylases / genetics. DNA Modification Methylases / metabolism. DNA Repair Enzymes / genetics. DNA Repair Enzymes / metabolism. Female. Gene Silencing. Humans. Salvage Therapy. Soft Tissue Neoplasms / enzymology. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / therapy. Tumor Suppressor Proteins / genetics. Tumor Suppressor Proteins / metabolism

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  • (PMID = 20805657.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Tumor Suppressor Proteins; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
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26. Ishibashi H, Akamatsu H, Kojima K, Usui H, Akashi T, Sunamori M: Good syndrome with thymic adenosquamous carcinoma--report of a case. Ann Thorac Cardiovasc Surg; 2007 Feb;13(1):50-2
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  • An extended thymo-thymectomy with lymph nodes dissection was performed for an irregular shaped anterior mediastinum mass.
  • The tumor was mainly composed of type C, adenosquamous carcinoma, and found to have a small area of types B2 and B3 thymoma.
  • History and laboratory findings were compatible with the diagnosis of Good syndrome.
  • [MeSH-major] Carcinoma, Adenosquamous. Paraneoplastic Syndromes. Thymoma. Thymus Neoplasms
  • [MeSH-minor] Aged. Humans. Lymph Node Excision. Male. Mediastinal Neoplasms / secondary. Mediastinal Neoplasms / surgery. Neoplasm Invasiveness. Thymectomy

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  • (PMID = 17392673.001).
  • [ISSN] 1341-1098
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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27. Tang M, Liu QM, Zhou SH, Chai XP: [Analysis on an early diagnosis grading model for acute aortic dissection]. Zhonghua Xin Xue Guan Bing Za Zhi; 2010 May;38(5):425-8
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  • [Title] [Analysis on an early diagnosis grading model for acute aortic dissection].
  • OBJECTIVE: To investigate the value of an early diagnosis grading model derived from the clinical manifestation, laboratory and imaging data for the diagnosis of aortic dissection (AD).
  • METHODS: An early diagnosis grading model was established based on the clinical manifestation, laboratory and imaging data from 182 AD patients who admitted to our department during the last 3 years, 184 patients with chest and back pain served as controls.
  • CONCLUSION: The emergency diagnose of AD could be improved based on the established early grading model based on the stabbing and severe pain, rapid blood pressure increase, asymmetry of the blood pressure and/or the pulse, widened aortic knob, mediastinum or descending aorta on X-ray, and significantly increased D-dimmer level.
  • [MeSH-major] Aneurysm, Dissecting / diagnosis. Aortic Aneurysm / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Aorta, Thoracic / pathology. Back Pain. Chest Pain. Diagnostic Imaging. Early Diagnosis. Female. Humans. Male. Middle Aged. Sensitivity and Specificity

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  • (PMID = 20654102.001).
  • [ISSN] 0253-3758
  • [Journal-full-title] Zhonghua xin xue guan bing za zhi
  • [ISO-abbreviation] Zhonghua Xin Xue Guan Bing Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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28. Nakamoto M, Aburaya N, Sato Y, Konishi K, Yoshino I, Hashizume M, Tamura S: Thoracoscopic surgical navigation system for cancer localization in collapsed lung based on estimation of lung deformation. Med Image Comput Comput Assist Interv; 2007;10(Pt 2):68-76
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  • In our system, the thoracic cage and mediastinum are localized using rigid registration between the intraoperatively digitized surface points and the preoperative CT surface model, and then the lung deformation field is estimated using nonrigid registration between the registered and digitized point datasets on the collapsed lung surface and the preoperative CT lung surface model to predict cancer locations.
  • [MeSH-major] Imaging, Three-Dimensional / methods. Lung Neoplasms / diagnosis. Lung Neoplasms / surgery. Pattern Recognition, Automated / methods. Radiographic Image Interpretation, Computer-Assisted / instrumentation. Radiography, Interventional / instrumentation. Thoracoscopes

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  • (PMID = 18044554.001).
  • [Journal-full-title] Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
  • [ISO-abbreviation] Med Image Comput Comput Assist Interv
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
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29. Allen TC, Bag R, Zander DS, Cagle PT: Cytomegalovirus infection masquerading as carcinoma in a lung transplant patient. Arch Pathol Lab Med; 2005 Jan;129(1):e1-3
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  • Solitary nodules suggesting neoplasm may arise in lung transplant patients with lung infections.
  • Five months later, a solitary mass was identified on chest radiograph in the left upper lobe and left superior mediastinum.
  • [MeSH-major] Carcinoma / diagnosis. Cytomegalovirus / isolation & purification. Cytomegalovirus Infections / diagnosis. Lung Neoplasms / diagnosis. Lung Transplantation / adverse effects
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged


30. Best-Aguilera CR, Vazquez-Del Mercado M, Muñoz-Valle JF, Herrera-Zarate L, Navarro-Hernandez RE, Martin-Marquez BT, Oregon-Romero E, Ruiz-Quezada S, Bonilla GM, Lomeli-Guerrero A: Massive myeloid sarcoma affecting the central nervous system, mediastinum, retroperitoneum, liver, and rectum associated with acute myeloblastic leukaemia: a case report. J Clin Pathol; 2005 Mar;58(3):325-7
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  • [Title] Massive myeloid sarcoma affecting the central nervous system, mediastinum, retroperitoneum, liver, and rectum associated with acute myeloblastic leukaemia: a case report.
  • This report describes a myeloid sarcoma associated with AML with tumour formation at five anatomical sites.
  • The anatomical sites affected were: the rectum, the right lobe of the liver, the mediastinum, the retroperitoneum, and the central nervous system.


31. Debray MP, Marchand-Adam S, Soufan R, Ostinelli J, Brillet PY, Schouman-Claeys E, Crestani B: Retrosternal and pleural "bridging" fibrosis mimicking malignancy in a patient exposed to asbestos. Eur Respir Rev; 2010 Jun;19(116):158-60
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  • Mediastinal fibrosis is a rare, benign disorder characterised by proliferation of fibrous tissue within the mediastinum.
  • It can present as diffuse mediastinal infiltration or, more frequently, as a localised soft tissue mass, usually in the right paratracheal or subcarinal areas.
  • Herein, we present an unusual pattern of mediastinal fibrosis, presenting as a thick retrosternal mass contiguous with pleural thickening.
  • Histopathological proof of benign fibrosis was obtained by surgery.
  • [MeSH-major] Asbestosis / pathology. Mediastinal Neoplasms / pathology. Mediastinum / pathology. Pleura / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Fibrosis. Humans. Male. Middle Aged. Positron-Emission Tomography. Sternum. Tomography, X-Ray Computed

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  • (PMID = 20956185.001).
  • [ISSN] 1600-0617
  • [Journal-full-title] European respiratory review : an official journal of the European Respiratory Society
  • [ISO-abbreviation] Eur Respir Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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32. Gupta R, Park HY, Kim H, Um SW: Endobronchial inflammatory polyp as a rare complication of endobronchial ultrasound-transbronchial needle aspiration. Interact Cardiovasc Thorac Surg; 2010 Sep;11(3):340-1
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  • Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) offers a minimally invasive option for staging the mediastinum in suspected lung cancer but also in the diagnosis of mediastinal lesions accessible from the airways.
  • EBUS-TBNA has been widely used for the evaluation of mediastinal and hilar lesions for several reasons, such as its minimally invasive nature, high diagnostic accuracy, needle aspiration under real-time visualization and excellent safety profile.
  • [MeSH-major] Biopsy, Needle / adverse effects. Bronchial Diseases / etiology. Endosonography / adverse effects. Inflammation / etiology. Polyps / etiology. Tuberculosis, Lymph Node / diagnosis

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  • (PMID = 20591893.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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33. Hasegawa Y, Tomita K, Hashimoto K, Shigeoka Y, Watanabe M, Yamasaki A, Shimizu E: Des-gamma-carboxy prothrombin (PIVKA-II)-producing mediastinal embryonal carcinoma with features of hepatoid differentiation. Anticancer Res; 2005 Nov-Dec;25(6C):4569-71
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  • [Title] Des-gamma-carboxy prothrombin (PIVKA-II)-producing mediastinal embryonal carcinoma with features of hepatoid differentiation.
  • The case of a 48-year-old man with primary nonseminomatous embryonal carcinoma at the posterior mediastinum is described.
  • The patient displayed extremely high plasma levels of Des-gamma-carboxy prothrombin (PIVKA-II) (4040 mAU/ml).
  • After preoperative systemic chemotherapy, total tumor resection was performed.
  • These results indicate that tumor cells, which are manifested as hepatoid differentiation, may produce PIVKA-II.
  • This case seems to be the first case reported in which PIVKA-II was produced by nonseminomatous mediastinal embryonal carcinoma without HCC or liver metastasis.
  • [MeSH-major] Biomarkers / blood. Carcinoma, Embryonal / blood. Carcinoma, Hepatocellular / pathology. Liver Neoplasms / pathology. Mediastinal Neoplasms / blood. Protein Precursors / blood
  • [MeSH-minor] Cell Differentiation / physiology. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. Prothrombin

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  • (PMID = 16334143.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Protein Precursors; 53230-14-1 / acarboxyprothrombin; 9001-26-7 / Prothrombin
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34. Cheng MF, Tsai CS, Chiang PC, Lee HS: Cardiac tamponade as manifestation of advanced thymic carcinoma. Heart Lung; 2005 Mar-Apr;34(2):136-41
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  • Thymic carcinoma, a malignant thymoma, is rare in the anterior mediastinum.
  • Typically it occurs after age 40 years, presents as an asymptomatic disorder for prolonged periods of time, and is incidentally detected by chest radiograph.
  • We now report the case of a 47-year-old man who experienced sudden onset syncope because of cardiac tamponade and massive pleural and pericardial effusions resulting from a huge thymic tumor.
  • The tumor and lung lesion were resected.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Cardiac Tamponade / etiology. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Antimetabolites, Antineoplastic / therapeutic use. Antineoplastic Agents / therapeutic use. Cisplatin / therapeutic use. Combined Modality Therapy. Echocardiography. Electrocardiography. Female. Fluorouracil. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Male. Middle Aged. Pericardial Effusion / etiology. Pericardial Effusion / surgery. Pericardial Effusion / ultrasonography. Pericardiocentesis. Postoperative Care. Radiography, Thoracic. Radiotherapy Dosage. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15761459.001).
  • [ISSN] 0147-9563
  • [Journal-full-title] Heart & lung : the journal of critical care
  • [ISO-abbreviation] Heart Lung
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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35. Sakao Y, Miyamoto H, Yamazaki A, Ou S, Shiomi K, Sonobe S, Sakuraba M: The spread of metastatic lymph nodes to the mediastinum from left upper lobe cancer: results of superior mediastinal nodal dissection through a median sternotomy. Eur J Cardiothorac Surg; 2006 Sep;30(3):543-7
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  • [Title] The spread of metastatic lymph nodes to the mediastinum from left upper lobe cancer: results of superior mediastinal nodal dissection through a median sternotomy.
  • BACKGROUND: This study endeavored to clarify the location, frequency, and prognostic value of metastatic lymph nodes in the mediastinum among patients with left upper lung cancer who underwent complete dissection of the superior mediastinal lymph node through a median sternotomy.
  • METHODS: Forty-four patients with left upper lobe cancer underwent extended radical mediastinal nodal dissection (ERD), all of whom were analyzed in this retrospective study.
  • Mediastinal nodal status was assessed according to the systems of Mountain/Dresler 7 and Naruke 8.
  • The clinicopathological records of each patient were examined for prognostic factors, including age, sex, histology, tumor size, c-N number, preoperative serum CEA level, metastatic stations and distribution of metastatic nodes according to Naruke's system 8.
  • The superior mediastinal lymph nodes which cannot be dissected through a left thoracotomy (bilateral #1 and #2, #3, right #3a, and right #4 according to Naruke's map 8 were defined as extra-superior mediastinal nodes for left lung cancer (ESMD).
  • RESULTS: Fourteen patients had one or more metastases to mediastinal lymph nodes, among whom the most common metastatic station was the aortic nodes: 71.4% had metastasis to #5 or #6 (57.1% to #5 and 50% to #6).
  • Metastasis to the ESMD occurred in 7 of the 44 study subjects (16%), representing a 50% rate of occurrence (7/14) among those with mediastinal nodal involvement.
  • [MeSH-major] Lung Neoplasms / pathology. Mediastinal Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Aorta / pathology. Bronchial Neoplasms / pathology. Bronchial Neoplasms / secondary. Dissection / methods. Female. Humans. Lymphatic Metastasis. Male. Mediastinum / pathology. Mediastinum / surgery. Middle Aged. Prognosis. Retrospective Studies. Sternum / surgery. Survival Analysis. Thoracic Surgical Procedures. Tracheal Neoplasms / pathology. Tracheal Neoplasms / secondary

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  • (PMID = 16870462.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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36. von der Weid NX: Adult life after surviving lymphoma in childhood. Support Care Cancer; 2008 Apr;16(4):339-45
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  • Large enough prospective cohort studies like the CCSS in the USA were able to show an increased risk of second malignant neoplasms, especially brain tumors in patients formerly treated with cranial irradiation.
  • Cardiac function must be serially evaluated over the long to very long-term because of potential cardiomyopathy after high anthracycline doses and/or mediastinal irradiation.
  • Radiation therapy to the neck and mediastinum (mantle field) induces a 50% risk of developing hypothyroidism and a 20% risk of developing thyroid nodules at 20 years.
  • Other structures affected by mediastinal irradiation are the heart (pericardial, myocardial and endocardial structures), the great arteries (fibrosis, stenosis, aneurysms) and the central portion of the lungs (diffusion troubles, restrictive pneumopathy).
  • [MeSH-minor] Adult. Child. Cognition Disorders / etiology. Endocrine System / physiopathology. Follow-Up Studies. Humans. Neoplasms, Radiation-Induced. Neoplasms, Second Primary

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  • (PMID = 18196290.001).
  • [ISSN] 0941-4355
  • [Journal-full-title] Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
  • [ISO-abbreviation] Support Care Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 41
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37. Tachibana M, Hirahara N, Kinugasa S, Yoshimura H: Clinicopathologic features of superficial esophageal cancer: results of consecutive 100 patients. Ann Surg Oncol; 2008 Jan;15(1):104-16
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  • BACKGROUND: The depth of tumor penetration is a crucial factor in determining the prognosis of patients with esophageal carcinoma.
  • Patient and tumor characteristics of those 100 patients were studied.
  • Among 17 patients with nodal involvement, 4 patients with upper thoracic SEC had upper mediastinum and/or cervical nodal metastases, 11 patients with middle thoracic SEC had widespread upper and lower mediastinal and abdominal metastases, and 2 patients with lower thoracic SEC had lower and abdominal lymph node metastases.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Squamous Cell / pathology. Esophageal Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Epithelium / pathology. Esophagectomy. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Mucous Membrane / pathology. Neoplasm Staging. Prognosis. Survival Rate

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  • (PMID = 17891442.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Mabuchi M, Imamura M, Kubo N, Morita K, Noriyasu K, Tsukamoto T, Yasuda K, Tamaki N: Sympathetic denervation and reinnervation after the maze procedure. J Nucl Med; 2005 Jul;46(7):1089-94
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  • All patients underwent cardiac 123I-MIBG imaging preoperatively and 10 d and 1 y after surgery to assess 123I-MIBG uptake (heart-to-mediastinum count ratio of early planar images [H/M]) and the washout rate (WR).

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  • (PMID = 16000276.001).
  • [ISSN] 0161-5505
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 35MRW7B4AD / 3-Iodobenzylguanidine
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39. Nakamura Y, Matsumura A, Katsura H, Sakaguchi M, Ito N, Kitahara N, Ose N, Kitaichi M: Cisplatin-based chemotherapy followed by surgery for malignant nonseminomatous germ cell tumor of mediastinum: one institution's experience. Gen Thorac Cardiovasc Surg; 2009 Jul;57(7):363-8
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  • [Title] Cisplatin-based chemotherapy followed by surgery for malignant nonseminomatous germ cell tumor of mediastinum: one institution's experience.
  • OBJECTIVE: The objective of this study was to evaluate the efficacy and safety of cisplatin-based chemotherapy followed by surgery for patients with a malignant nonseminomatous germ cell tumor (NSGCT) of the mediastinum.
  • Each patient underwent complete surgical resection of the residual tumor following chemotherapy.
  • A yolk sac tumor was detected in one patient and malignant teratoma along with a yolk sac tumor in one patient postoperatively.
  • CONCLUSION: Postchemotherapy surgical resection of the residual tumor plays an integral role in the management of patients with NSGCT.
  • The presence of viable tumor cells in the resected specimens is associated with poor survival.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Mediastinal Neoplasms / drug therapy. Neoadjuvant Therapy. Neoplasms, Germ Cell and Embryonal / drug therapy
  • [MeSH-minor] Bleomycin / administration & dosage. Bleomycin / therapeutic use. Cisplatin / administration & dosage. Cisplatin / therapeutic use. Combined Modality Therapy. Etoposide / administration & dosage. Etoposide / therapeutic use. Humans. Male. Neoplasm, Residual. Prognosis. Survival Analysis

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  • (PMID = 19597926.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; BEP protocol
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40. Krüger S, Kratochwil C, Schumann C, Wibmer T, Pauls S, Merk T: [Primitive neuroectodermal tumour of the mediastinum as a rare cause of pericardial effusion]. Pneumologie; 2007 Dec;61(12):801-2
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  • [Title] [Primitive neuroectodermal tumour of the mediastinum as a rare cause of pericardial effusion].
  • [Transliterated title] Primitiver neuroektodermaler Tumor des Mediastinums als seltene Ursache eines Perikardergusses.
  • [MeSH-major] Mediastinal Neoplasms / complications. Mediastinal Neoplasms / diagnosis. Neuroectodermal Tumors / complications. Neuroectodermal Tumors / diagnosis. Pericardial Effusion / diagnosis. Pericardial Effusion / etiology
  • [MeSH-minor] Adult. Humans. Male. Positron-Emission Tomography. Rare Diseases / complications. Rare Diseases / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 18098071.001).
  • [ISSN] 1438-8790
  • [Journal-full-title] Pneumologie (Stuttgart, Germany)
  • [ISO-abbreviation] Pneumologie
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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41. Asilsoy S, Apa H, Ağin H, Can D, Kayserili E, Karasoy I, Hizarcioğlu M, Gülez P: [Pneumomediastinum and subcutaneous emphysema during asthmatic attacks in three patients]. Tuberk Toraks; 2009;57(2):218-22
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  • Pneumomediastinum is defined as free air or other gases contained within the mediastinum.
  • [MeSH-major] Asthma / complications. Mediastinal Emphysema / etiology. Subcutaneous Emphysema / etiology

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  • (PMID = 19714516.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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42. Yuzbasioglu MF, Ozkaya M, Ezberci F, Senoglu N, Kizildag B: Eggshell calcification after intrathyroidal hemorrhage of retrosternal thyroid. Cases J; 2008;1(1):11
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  • A 67-year-old man with chronic cough and recent dysphagia was found to have a retrosternal mass extending into the visceral mediastinum on chest roentgenogram.
  • A computed tomographic (CT) scan confirmed eggshell callcification, which was 53 x 53 x 80 mm in size a retrosternal thyroid mass and revealed significant tracheal deviation to the right due to an extensive mass surrounded by a calcificated capsule in the left lobe of the thyroid gland with extension to the upper mediastinum.

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  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
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  • [Other-IDs] NLM/ PMC2438315
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43. Koskinas KC, Oikonomou K, Karapatsoudi E, Makridis P: Echocardiographic manifestation of hiatus hernia simulating a left atrial mass: case report. Cardiovasc Ultrasound; 2008;6:46
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  • A subsequent computed tomography scan visualized a hiatus hernia in the posterior mediastinum, impinging on the posterior left atrial wall.
  • Physicians should be aware of the clinical and sonographic findings to facilitate the differential diagnosis from similarly presenting cardiac entities.
  • [MeSH-major] Echocardiography. Heart Neoplasms / ultrasonography. Hernia, Hiatal / radiography. Hernia, Hiatal / ultrasonography. Tomography, X-Ray Computed
  • [MeSH-minor] Aged, 80 and over. Barium. Diagnosis, Differential. Female. Heart Atria. Humans. Radiography, Thoracic

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  • (PMID = 18793386.001).
  • [ISSN] 1476-7120
  • [Journal-full-title] Cardiovascular ultrasound
  • [ISO-abbreviation] Cardiovasc Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 24GP945V5T / Barium
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44. Gill KR, Wallace MB: Endoscopic ultrasound and staging of non-small cell lung cancer. Minerva Med; 2007 Aug;98(4):323-30
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  • In the case of non small-cell lung cancer (NSCLC), the most important parameters for optimal treatment and prognosis are the presence of cancer spread to the lymph nodes within the mediastinum, and to distant organs.
  • Endoscopic ultrasound (EUS) has become a significant tool for the assessment of mediastinal lymph nodes, and in some cases, distant organ metastases because of its minimally invasive access to these sites through a trans-esophageal or trans-gastric approach.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Carcinoma, Non-Small-Cell Lung / ultrasonography. Endosonography / methods. Lung Neoplasms / ultrasonography. Neoplasm Staging / methods
  • [MeSH-minor] Humans. Lung / pathology. Lung / ultrasonography. Lymphatic Metastasis. Mediastinum / pathology. Mediastinum / ultrasonography


45. Teixeira M, Gil F, Vazquez JM, Cardoso L, Arencibia A, Ramirez-Zarzosa G, Agut A: Helical computed tomographic anatomy of the canine abdomen. Vet J; 2007 Jul;174(1):133-8
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  • All sections were imaged with soft-tissue window settings and the cranial abdomen was also imaged with mediastinum-vascular window settings.

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  • (PMID = 16766214.001).
  • [ISSN] 1090-0233
  • [Journal-full-title] Veterinary journal (London, England : 1997)
  • [ISO-abbreviation] Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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46. Anandasabapathy S: Endoscopic ultrasound: indications and applications. Mt Sinai J Med; 2006 Jul;73(4):702-7
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  • It is a safe and accurate method of diagnosing and staging a variety of benign and malignant lesions.
  • Additionally, EUS-guided fine-needle aspiration can be performed on areas surrounding the gastrointestinal tract, including adjacent organs (pancreas, liver, etc.) and the mediastinum.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / ultrasonography. Endosonography. Gastrointestinal Neoplasms / ultrasonography

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  • (PMID = 16878276.001).
  • [ISSN] 0027-2507
  • [Journal-full-title] The Mount Sinai journal of medicine, New York
  • [ISO-abbreviation] Mt. Sinai J. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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47. Gagua PO, Macharashvili LI, Kuchava VO, Gzirishvili LM, Lomidze ZT: [Diagnosis and results of surgical treatment of rare giant intrathoracic tumors]. Khirurgiia (Mosk); 2005;(12):21-4
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  • [Title] [Diagnosis and results of surgical treatment of rare giant intrathoracic tumors].
  • The tumor located in the mediastinum in 8 patients, in the lungs -- in 6, in the chest wall with intrathoracic growth -- in 5 patients.
  • Computed tomography and CT-assisted puncture biopsy improve the quality of preoperative diagnosis.
  • Radical surgery is the method of choice in surgical treatment of giant benign intrathoracic tumors.
  • [MeSH-major] Hemangiosarcoma / radiography. Hemangiosarcoma / surgery. Liposarcoma / radiography. Liposarcoma / surgery. Thoracic Neoplasms / radiography. Thoracic Neoplasms / surgery. Thoracic Surgical Procedures / methods
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 16353021.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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48. Barczyński M, Cichoń S, Konturek A, Cichoń W: A randomised study on a new cost-effective algorithm of quick intraoperative intact parathyroid hormone assay in secondary hyperparathyroidism. Langenbecks Arch Surg; 2005 Apr;390(2):121-7
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  • The assay was helpful in identifying patients with supranumerary hyperfunctioning parathyroid tissue (5.9% vs 7.8% in group A and B, respectively), patients with fewer than four parathyroid glands (3.9% vs 5.9% in group A and B, respectively) and patients with remaining hyperfunctioning parathyroid tissue suspected to be located within the mediastinum in cases of negative bilateral neck exploration who benefit from transcervical thymectomy.

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  • (PMID = 15711996.001).
  • [ISSN] 1435-2443
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Germany
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49. Rückbeil O, Burghardt J, Gellert K: Thoracoscopic removal of a transesophageal ingested mediastinal foreign body. Interact Cardiovasc Thorac Surg; 2009 Sep;9(3):556-7
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  • [Title] Thoracoscopic removal of a transesophageal ingested mediastinal foreign body.
  • Transesophageal migration of a foreign body into the mediastinum in human adults is rare.
  • The authors describe the case of a successfully performed thoracoscopic approach to remove an ingested needle from the mediastinum posterior of a 69-year-old patient.
  • [MeSH-major] Esophagus. Foreign-Body Migration / surgery. Mediastinum. Needles. Thoracoscopy

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  • (PMID = 19541692.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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50. Kosaka T, Nakagawa M, Ishida M, Iino K, Watanabe H, Hasegawa H, Ito H: Cardioprotective effect of an L/N-type calcium channel blocker in patients with hypertensive heart disease. J Cardiol; 2009 Oct;54(2):262-72
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  • Cardiac sympathetic activity was assessed as early and delayed heart to mediastinum (H/M) ratios and a washout rate (WR), using (123)I-MIBG imaging.

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  • (PMID = 19782264.001).
  • [ISSN] 1876-4738
  • [Journal-full-title] Journal of cardiology
  • [ISO-abbreviation] J Cardiol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Calcium Channel Blockers; 0 / Dihydropyridines; 97T5AZ1JIP / cilnidipine; CZ5312222S / Nicardipine
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51. Malagón HD, Valdez AM, Moran CA, Suster S: Germ cell tumors with sarcomatous components: a clinicopathologic and immunohistochemical study of 46 cases. Am J Surg Pathol; 2007 Sep;31(9):1356-62
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  • Twenty-three tumors arose in the mediastinum, 2 in the retroperitoneum, and 21 in the gonads.
  • The germ cell component consisted of pure mature or immature teratoma (23 cases), teratoma mixed with other seminomatous or nonseminomatous components (17), pure seminoma (2), intratubular germ cell neoplasia (1), and yolk sac tumor (1).
  • The SC included embryonal rhabdomyosarcoma (29), angiosarcoma (6), leiomyosarcoma (4), undifferentiated sarcoma (3), myxoid liposarcoma (1), malignant peripheral nerve sheath tumor (1), malignant "triton" tumor (1), and epithelioid hemangioendothelioma (1).
  • Thirty-two of 40 patients either died of tumor (25/40; 62.5%) or were alive with advanced, progressive disease (7/40; 17.5%), and only 8/40 (20%) were alive and free of disease between 5 to 40 months (mean=18 mo).
  • [MeSH-major] Immunohistochemistry. Mediastinal Neoplasms / diagnosis. Neoplasms, Germ Cell and Embryonal / diagnosis. Ovarian Neoplasms / diagnosis. Retroperitoneal Neoplasms / diagnosis. Sarcoma / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Orchiectomy. Ovariectomy. Time Factors. Treatment Outcome

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  • (PMID = 17721191.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Anslot C, Hulin S, Durandy Y: Postoperative mediastinitis in children: improvement of simple primary closed drainage. Ann Thorac Surg; 2007 Aug;84(2):423-8
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  • Mediastinal effluents were cultured every day, and the catheters were withdrawn when the effluent culture was negative for microorganisms.
  • The time to mediastinal sterilization was 4 days (range, 1 to 14 days), and the antibiotic course was 11 days (range, 7 to 28 days), with a hospital stay of 13 days (range, 10 to 30 days).
  • The time to mediastinal sterilization was 8 days (range, 3 to 10 days), and the antibiotic course was 30 days (range, 26 to 37 days), with a hospital stay of 37 days (range, 20 to 54 days).
  • The time to mediastinal sterilization was 6 days (range, 1 to 10 days), and the antibiotic course was 15 days (range, 10 to 31 days), with a hospital stay of 20 days (range, 18 to 36 days).
  • None of the deaths was directly related to mediastinitis, as the mediastinum was sterile in all 3 patients before death.
  • CONCLUSIONS: This simple treatment was efficient and reliable in achieving mediastinal sterilization.

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  • (PMID = 17643610.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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53. Chen PY, Chen WY, Ho DM, Pan CC: Malignant ganglioneuroma arising from mediastinal mixed germ cell tumor. J Chin Med Assoc; 2007 Feb;70(2):76-9
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  • [Title] Malignant ganglioneuroma arising from mediastinal mixed germ cell tumor.
  • Mixed germ cell tumors with non-germ cell malignant components rarely occur in the anterior mediastinum.
  • We report a case of a 34-year-old man who presented with an anterior mediastinum mass.
  • Mixed germ cell tumor was initially diagnosed based on the pathologic findings of germinoma on thoracoscopic biopsy and clinical findings of elevated serum alpha-fetoprotein and beta-human chorionic gonadotropin.
  • The patient received preoperative chemotherapy and subsequent complete resection of the residual tumor.
  • To our knowledge, this is the first reported case of a malignant ganglioneuroma arising from mediastinal mixed germ cell tumor.
  • [MeSH-major] Ganglioneuroma / etiology. Mediastinal Neoplasms / complications. Neoplasms, Germ Cell and Embryonal / complications

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  • (PMID = 17339149.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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54. Lerut T, De Leyn P, Coosemans W, Decaluwé H, Decker G, Nafteux P, Van Raemdonck D: Cervical videomediastinoscopy. Thorac Surg Clin; 2010 May;20(2):195-206
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  • Cervical mediastinoscopy is a frequently used technique to assess the mediastinum, in particular the mediastinal lymph nodes in patients presenting with non-small cell lung cancer (NSCLC).
  • This article discusses the current deployment of videomediastinoscopy in the diagnosis and management of NSCLC.
  • [MeSH-minor] Bronchi / blood supply. Carcinoma, Non-Small-Cell Lung / diagnosis. Carcinoma, Non-Small-Cell Lung / surgery. Endosonography. Humans. Intraoperative Complications / prevention & control. Lung Neoplasms / diagnosis. Lung Neoplasms / surgery. Lymph Node Excision / methods. Mediastinoscopes

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20451130.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
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55. Melo IA, Camargo Jde J, Gomes Bde M, Cabrera GA, Machuca TN: [Isolated mediastinal cystic lymphangioma]. Rev Port Pneumol; 2009 Jul-Aug;15(4):697-703
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  • [Title] [Isolated mediastinal cystic lymphangioma].
  • [Transliterated title] Linfangioma cístico isolado do mediastino.
  • A 59 years old female patient, asymptomatic, with the incidental finding of an ovarian tumor in her routine gynecological evaluation, and during the preoperative examinations it was incidentally found an isolated mediastinal tumor, and then routed to diagnostic evaluation of the lesion, which later proved to be a cystic lymphangioma.
  • The cystic hygroma of the mediastinum is a benign tumor and very infrequent, representing only 0.7 to 4.5% of all mediastinal tumors, and of these, only 1% is exclusively mediastinal in location.
  • The definitive diagnosis is only possible by pathological examination, and the recommended treatment consists of complete surgical resection.
  • [MeSH-major] Lymphangioma, Cystic. Mediastinal Neoplasms

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  • (PMID = 19547899.001).
  • [ISSN] 2172-6825
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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56. Cvijanović V, Stanić V, Ristanović A, Gulić B, Durković S, Stamenović D, Marić N, Kovacević S: [Thoracic surgery in solving enormous elevation of the left hemidiaphragm]. Vojnosanit Pregl; 2007 Apr;64(4):279-82
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  • After thoracotomy and plication of the bulging diaphragm, lung compression did not exist any more and mediastinum went back in the normal position.

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  • (PMID = 17580540.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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57. Murakawa T, Yoshida Y, Fukami T, Nakajima J: Life-threatening tracheal perforation secondary to descending necrotizing mediastinitis. Interact Cardiovasc Thorac Surg; 2010 Mar;10(3):454-6
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  • Survival from destruction of the mediastinal structures secondary to descending necrotizing mediastinitis (DNM) is very rare.
  • A 34-year-old man with a history of type 1 diabetes mellitus, diagnosed as pharyngeal abscess and subsequent DNM affecting the anterior mediastinum and paratracheal space, was referred to our institute.
  • The patient underwent cervico-mediastinal drainage for DNM.


58. Olgun H, Türkyilmaz A, Aydin Y, Ceviz N: Spontaneous pneumomediastinum in a child as a rare cause of chest pain. Turk Kardiyol Dern Ars; 2009 Jan;37(1):51-2
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  • Spontaneous pneumomediastinum is a rare disorder in children occurring mostly due to some triggering events.
  • On the chest radiogram, suspected mediastinal air was noted.
  • A left lateral chest X-ray revealed apparent presence of air in the anterior mediastinum.
  • [MeSH-major] Chest Pain / etiology. Mediastinal Emphysema / diagnosis
  • [MeSH-minor] Child. Diagnosis, Differential. Electrocardiography. Heart Auscultation. Humans. Male. Pericardial Effusion / diagnosis. Radiography, Thoracic

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  • (PMID = 19225255.001).
  • [ISSN] 1016-5169
  • [Journal-full-title] Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır
  • [ISO-abbreviation] Turk Kardiyol Dern Ars
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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59. Hosaka Y, Tsuchida M, Umezu H, Eimoto T, Hashimoto T, Shinohara H, Hayashi J: Primary thymic adenocarcinoma coexisting with type AB thymoma: a rare case with long-term survival. Gen Thorac Cardiovasc Surg; 2010 Sep;58(9):488-91; discussion 491-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thymic carcinoma is a rare tumor.
  • The patient was found to have an abnormal mediastinal shadow on chest X-ray.
  • A computed tomography scan revealed a round, 6.5-cm-diameter mass in the right anterior mediastinum.
  • The preoperative diagnosis was thymoma, and thymothymectomy was performed.
  • [MeSH-major] Adenocarcinoma, Papillary / complications. Thymoma / complications. Thymus Neoplasms / complications

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  • (PMID = 20859731.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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60. Thomas PA, Gilardoni A, Trousse D, D'Journo XB, Avaro JP, Doddoli C, Giudicelli R, Fuentes P: Colon interposition for oesophageal replacement. Multimed Man Cardiothorac Surg; 2009 Jan 1;2009(603):mmcts.2007.002956
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  • However, given its durability and function, colon interposition keeps elective indications in patients with benign or malignant oesophageal disease who are potential candidates for long survival.
  • Transposition through the posterior mediastinum in the oesophageal bed is the shortest one and thereby offers the best functional results.

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  • (PMID = 24413178.001).
  • [Journal-full-title] Multimedia manual of cardiothoracic surgery : MMCTS
  • [ISO-abbreviation] Multimed Man Cardiothorac Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
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61. Sánchez-Lázaro IJ, Almenar L, Blanes M, Martínez-Dolz L, Portolés M, Roselló E, Rivera M, Salvador A: Timing, etiology, and location of first infection in first year after heart transplantation. Transplant Proc; 2010 Oct;42(8):3017-9
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  • Etiologic diagnosis was established at microbiological culture.
  • Locations considered were systemic, pulmonary, genitourinary, cutaneous, oropharyngeal, mediastinal, sternal, gastrointestinal, and other.
  • Early-onset infections occur in critical care units, are caused by nosocomial organisms, and involve the sternum or mediastinum, whereas late- onset infections have a more varied etiology and preferentially affect the skin and genitourinary tract.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20970597.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Bhasin DK, Rana SS, Chandail VS, Nanda M, Sinha SK, Nagi B: Successful resolution of a mediastinal pseudocyst and pancreatic pleural effusion by endoscopic nasopancreatic drainage. JOP; 2005 Jul;6(4):359-64
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  • [Title] Successful resolution of a mediastinal pseudocyst and pancreatic pleural effusion by endoscopic nasopancreatic drainage.
  • CONTEXT: A mediastinal pseudocyst is an unusual complication of acute and chronic pancreatitis.
  • Successful resolution of a mediastinal pseudocyst with endoscopic transpapillary stent placement has been described in fewer than five cases.
  • CASE REPORT: We report a case of chronic pancreatitis with complete pancreas divisum together with a mediastinal pseudocyst and pancreatic pleural effusion in which magnetic resonance imaging and endoscopic retrograde pancreatography demonstrated communication of the abdominal pseudocyst with the posterior mediastinum through the diaphragmatic hiatus.
  • CONCLUSION: A communicating mediastinal pseudocyst can be successfully treated by endoscopic transpapillary nasopancreatic drainage alone.
  • [MeSH-major] Mediastinal Cyst / diagnosis. Mediastinal Cyst / therapy. Pancreatic Pseudocyst / diagnosis. Pancreatic Pseudocyst / therapy. Pancreatitis / complications. Pleural Effusion / therapy

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  • (PMID = 16006688.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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63. Zhou ZT, Wang JW, Yang L, Wang J, Zhang W: [Primary germ cell tumor in the mediastinum-report of 47 cases]. Zhonghua Zhong Liu Za Zhi; 2006 Nov;28(11):863-6
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  • [Title] [Primary germ cell tumor in the mediastinum-report of 47 cases].
  • OBJECTIVE: To investigate the clinical characterstics, effective treatment and prognosis in patients with primary germ cell tumors in the mediastinum.
  • CONCLUSION: Primary mediastinal serminoma is sensitive to radiotherapy or chemotherapy with a good prognosis, but the prognosis of primary mediastinal non-seminoma is poor.
  • Cisplatin-based chemotherapy still plays a key role in the treatment of primary mediastinal non-seminoma as the survival of those has been improved.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Mediastinal Neoplasms / therapy. Neoplasms, Germ Cell and Embryonal / therapy. Seminoma / therapy

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  • (PMID = 17416013.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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64. Lu SH, Hou YY, Tan YS, Xu JF, Zeng HY, Sujie AK, Wang XD, Bai CX: Clinical and histopathological alterations of lymphangioleiomyomatosis in 14 Chinese patients. Chin Med J (Engl); 2009 Aug 20;122(16):1895-900
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  • LAM can arise sporadically or in association with tuberous sclerosis complex (TSC), an autosomal inherited syndrome characterized by hamartoma-like tumor growth and pathologic features that are distinct from manifestations of pulmonary LAM.
  • There were some surprises in the autopsy case as several LAM cell emboli were found in the veins of mediastinum lymph nodes; LAM cells were found to be disseminated in soft tissues adjacent to the ilium.
  • CONCLUSIONS: Women with unexplained recurrent pneumothorax, tuberous sclerosis, or a diagnosis of primary spontaneous pneumothorax or emphysema in the setting of limited or absent tobacco use should undergo high-resolution computed tomography (HRCT) scan screening for LAM.
  • [MeSH-major] Lymphangioleiomyomatosis / diagnosis. Lymphangioleiomyomatosis / pathology

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  • (PMID = 19781367.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Contraceptives, Oral, Synthetic; 0 / Progestins; 4G7DS2Q64Y / Progesterone; HSU1C9YRES / Medroxyprogesterone
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65. Balci AE, Ozyurtkan MO: Clinical and surgical specifications of adult unilateral diaphragmatic eventration according to their aetiology in 28 patients. Importance of using diaphragmatic patch and minimal thoracotomy incision. Eur J Cardiothorac Surg; 2010 Mar;37(3):606-12
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  • OBJECTIVE: This study aims to determine the differences among various diaphragmatic eventration (DE) aetiologies and to compare the outcomes of the operation relative to the use of a diaphragmatic patch.
  • METHODS: Between 2003 and 2009, 28 patients with a DE who underwent surgery were classified according to the following aetiology: (a) previous operation or disease, (b) congenital/idiopathic and (c) trauma.
  • A high hemi-diaphragm (alone or associated with a blunt sinus or a wide mediastinum) was the most prominent chest X-ray (CXR) finding in 19 patients (68%).
  • CONCLUSIONS: Buttressing the diaphragm by patch after the plication can protect from recurrence of a DE or any diaphragmatic insufficiency.
  • Previous abdominal interventions may increase the complication rate after a DE operation.

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  • [Copyright] Copyright (c) 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
  • (PMID = 19699653.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Germany
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66. Di Monaco A, Bruno I, Sestito A, Lamendola P, Barone L, Bagnato A, Nerla R, Pisanello C, Giordano A, Lanza GA, Crea F: Cardiac adrenergic nerve function and microvascular dysfunction in patients with cardiac syndrome X. Heart; 2009 Apr;95(7):550-4
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  • Compared to controls, CSX patients showed a lower heart/mediastinum (H/M) ratio of MIBG uptake (1.69 (0.24) vs 2.2 (0.3), p<0.001) and a higher cardiac MIBG defect score (25 (22) vs 4 (2), p = 0.002).

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  • [CommentIn] Heart. 2009 Apr;95(7):521 [19164331.001]
  • (PMID = 19164330.001).
  • [ISSN] 1468-201X
  • [Journal-full-title] Heart (British Cardiac Society)
  • [ISO-abbreviation] Heart
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Vasodilator Agents; 35MRW7B4AD / 3-Iodobenzylguanidine; K72T3FS567 / Adenosine
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67. Dose-Schwarz J, Mahner S, Schirrmacher S, Jenicke L, Müller V, Habermann CR, Brenner W: [Detection of metastases in breast cancer patients: comparison of FDG PET with chest X-ray, bone scintigraphy and ultrasound of the abdomen]. Nuklearmedizin; 2008;47(3):97-103
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  • Distant metastases at primary diagnosis are a prognostic key factor in breast cancer patients and play a central role in therapeutic decisions.
  • Regarding different locations of metastases the sensitivity of FDG PET was superior in the detection of pulmonary metastases and lymph node metastases of the mediastinum in comparison to chest x-ray, whereas the sensitivity of FDG PET in the detection of bone and liver metastases was comparable with bone scintigraphy and ultrasound of the abdomen.
  • [MeSH-major] Abdomen / ultrasonography. Breast Neoplasms / radiography. Breast Neoplasms / radionuclide imaging. Breast Neoplasms / secondary. Fluorodeoxyglucose F18. Positron-Emission Tomography / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Humans. Middle Aged. Neoplasm Metastasis / radiography. Neoplasm Metastasis / radionuclide imaging. Radiography, Thoracic. Retrospective Studies

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  • (PMID = 18493688.001).
  • [ISSN] 0029-5566
  • [Journal-full-title] Nuklearmedizin. Nuclear medicine
  • [ISO-abbreviation] Nuklearmedizin
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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68. Ganz RA, Rydell M, Termin P: Accurate localization of tissue layers in the esophagus by using a double-lumen injection catheter: implications for the Enteryx procedure. Gastrointest Endosc; 2006 Mar;63(3):468-72
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  • The mediastinal cavity was searched for extravasated Enteryx material, and the esophagus was examined grossly for Enteryx adherent to the outside wall.
  • RESULTS: No extravasated Enteryx was found in the mediastinum in 60 injected sites.
  • CONCLUSIONS: By using a new injection device without fluoroscopy, Enteryx can be deposited consistently into the deep esophageal wall with a high degree of accuracy, avoiding mediastinal extravasation.

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  • (PMID = 16500398.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Polyvinyls; 142M471B3J / Carbon Dioxide; 25067-34-9 / ethylene-vinyl alcohol copolymer
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69. Elbl L, Vasova I, Kral Z, Navratil M, Smardova L, Vorlicek J: Echocardiographic evaluation of early and chronic cardiotoxicity in adult patients treated for Hodgkin's disease with ABVD regimen. Neoplasma; 2006;53(1):62-6
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  • Radiotherapy of the mediastinum was delivered to 27 (52%) patients with a mean dose 41+/-4 Gy (range 30-46; median 42).

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  • (PMID = 16416015.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5V9KLZ54CY / Vinblastine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin
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70. Thomson LE, Goodman MP, Naqvi TZ, Feldman R, Buchbinder NA, Waxman A, D'Agnolo A: Aortic root infection in a prosthetic valve demonstrated by gallium-67 citrate SPECT. Clin Nucl Med; 2005 Apr;30(4):265-8
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  • Gallium planar imaging demonstrated increased activity in the lumbar spine, suspicious for the presence of infection, and activity was noted in the mid mediastinum as well.

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  • (PMID = 15764887.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Citrates; 0 / Radiopharmaceuticals; 27905-02-8 / gallium citrate; CH46OC8YV4 / Gallium
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71. Telusca N, Le K, Palacios E, Friedlander PA: An unusual recurrent intrathoracic goiter: Case report. Ear Nose Throat J; 2010 Oct;89(10):E41-2
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  • Most intrathoracic goiters are located in the anterior mediastinum, frontal to the recurrent laryngeal nerve and anterolateral to the trachea.
  • Posterior mediastinal goiters account for only 10 to 15% of all intrathoracic goiters and arise from the posterolateral portion of the thyroid gland.
  • We present a case involving a 59-year-old man with history of gradual-onset dyspnea who was referred to us for evaluation of a large mediastinal mass.
  • Contrast-enhanced computed tomography demonstrated a large, well-circumscribed mass extending paratracheally from the thoracic inlet to the posterior mediastinum.

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  • (PMID = 20981652.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Ioncica AM, Malos A, Crisan E, Popescu C, Saftoiu A, Ciurea T: State-of-the art endoscopic imaging in lung cancer: should specialties collide or concur? J Gastrointestin Liver Dis; 2010 Mar;19(1):93-7
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  • Transesophageal endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) represents a method which not only allows the visualization of the upper gastrointestinal tract, but also offers good visualisation of the posterior and inferior mediastinum.
  • Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) permits the assessment of the tumors in the anterior mediastinum.
  • Based on previously published literature, it is obvious that this minimally invasive procedure now offers the possibility of tissue diagnosis in mediastinal masses including primary tumours or secondary lesions from both benign and malignant diseases.
  • [MeSH-major] Biopsy, Fine-Needle. Bronchoscopy. Echocardiography, Transesophageal. Endosonography. Lung Neoplasms / diagnosis. Ultrasonography, Interventional
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Staging. Predictive Value of Tests

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  • (PMID = 20361084.001).
  • [ISSN] 1841-8724
  • [Journal-full-title] Journal of gastrointestinal and liver diseases : JGLD
  • [ISO-abbreviation] J Gastrointestin Liver Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
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73. Turgut B, Elagoz S, Erselcan T, Koyuncu A, Dokmetas HS, Hasbek Z, Ozdemir S, Aydin C: Preoperative localization of parathyroid adenomas with technetium-99m methoxyisobutylisonitrile imaging: relationship with P-glycoprotein expression, oxyphilic cell content, and tumoral tissue volume. Cancer Biother Radiopharm; 2006 Dec;21(6):579-90
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  • In addition to tumor size, it has been suggested that P-glycoprotein (P-gp) expression and/or oxyphilic cell content in parathyroid adenomas has an important influence on the results of technetium 99m methoxyisobutylisonitrile (Tc-99m MIBI) parathyroid imaging.
  • Preoperatively, "double phase" parathyroid scintigraphy with Tc-99m MIBI (including imaging of the neck and mediastinum) was performed in all patients.
  • [MeSH-major] Organotechnetium Compounds. Oxyphil Cells / metabolism. Oxyphil Cells / pathology. P-Glycoproteins / metabolism. Parathyroid Neoplasms / metabolism. Parathyroid Neoplasms / radiography

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  • (PMID = 17257073.001).
  • [ISSN] 1084-9785
  • [Journal-full-title] Cancer biotherapy & radiopharmaceuticals
  • [ISO-abbreviation] Cancer Biother. Radiopharm.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organotechnetium Compounds; 0 / P-Glycoproteins
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74. Kozuki A, Shinozaki H, Tajima A, Kase K: Successful treatment for descending necrotizing mediastinitis with severe thoracic emphysema using video-assisted thoracoscopic surgery. Gen Thorac Cardiovasc Surg; 2010 Nov;58(11):584-7
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  • Descending necrotizing mediastinitis (DNM) is a rare, highly fatal disease that occurs as a complication of a cervical or odontogenic infection spreading into the mediastinum.
  • Chest enhanced computed tomography on admission revealed massive left pleural effusion, pneumothorax, absolute collapse of the left lung, and a mediastinal shift to the right side with emphysema.
  • We urgently performed left thoracic and mediastinal drainage using VATS.
  • Retropharyngeal and upper mediastinal drainage was performed transcervically on the third hospital day.
  • We believe that VATS is a less invasive, effective modality for draining the posterior mediastinum.
  • [MeSH-major] Drainage / methods. Mediastinal Emphysema / surgery. Mediastinitis / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 21069499.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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75. Haga T, Nakajima Y, Kitamura A, Kuroda F, Takiguchi Y, Tatsumi K: [A rare case of large cell neuroendocrine carcinoma of the thymus]. Nihon Kokyuki Gakkai Zasshi; 2010 Oct;48(10):755-8
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  • Chest computed tomography (CT) showed a 48-mm mass in the anterior mediastinum.
  • CT-guided percutaneous tumor biopsy demonstrated large cell neuroendocrine carcinoma of the thymus.
  • Because the tumor had already progressed to stage IVb according to the Masaoka classification of thymic epithelial tumors, the patient was treated with combination chemotherapy of cisplatin and irinotecan, which achieved a partial response.
  • However, the tumor relapsed in February 2008.
  • [MeSH-major] Carcinoma, Neuroendocrine / drug therapy. Thymus Neoplasms / drug therapy

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  • (PMID = 21066864.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 7673326042 / irinotecan; Q20Q21Q62J / Cisplatin; XT3Z54Z28A / Camptothecin
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76. Saitoh H, Enomoto T, Narato R, Shibuya Y, Tanaka M, Nakamura S: [A case of sarcoidosis with an endobronchial polypoid lesion]. Nihon Kokyuki Gakkai Zasshi; 2010 Aug;48(8):589-94
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  • Chest radiography and CT showed lymphadenopathy in the mediastinum and bilateral hilum.

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  • (PMID = 20803976.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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77. Bagaturiia GO: [Two-stage surgical method of treatment of locally disseminated cancer of the thyroid]. Vestn Khir Im I I Grek; 2010;169(2):48-51
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  • It was shown that in elderly patients having many coexisting diseases with vast dissemination of the primary tumor with invasion to the surrounding organs and tissues and involvement of lymph nodes on the neck on both sides and in the mediastinum the operations should be divided into 2 stages.
  • [MeSH-major] Neck Dissection / methods. Thyroid Neoplasms / secondary. Thyroid Neoplasms / surgery. Thyroidectomy / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Treatment Outcome. Young Adult

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  • (PMID = 20552790.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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78. Akutsu Y, Kaneko K, Kodama Y, Li HL, Kawamura M, Asano T, Tanno K, Shinozuka A, Gokan T, Kobayashi Y: The significance of cardiac sympathetic nervous system abnormality in the long-term prognosis of patients with a history of ventricular tachyarrhythmia. J Nucl Med; 2009 Jan;50(1):61-7
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  • SNS activity was assessed using the heart-to-mediastinum ratio on delayed imaging.
  • SNS abnormality, defined as a heart-to-mediastinum ratio of less than 2.8, and left ventricular dysfunction, defined as a left ventricular ejection fraction of less than 50%, were associated with sudden cardiac death or recurrent ventricular tachyarrhythmic events (18/40 patients [45%] with SNS abnormality, vs. 6/46 patients [13%] without, P=0.004; 9/15 patients [60%] with left ventricular dysfunction, vs. 15/71 patients [21.1%] without, P=0.008).
  • [MeSH-major] Autonomic Nervous System Diseases / complications. Heart / innervation. Tachycardia, Ventricular / complications. Tachycardia, Ventricular / diagnosis

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  • (PMID = 19091900.001).
  • [ISSN] 0161-5505
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Yomono HS, Kurisaki H, Hebisawa A, Sakiyama Y, Saito Y, Murayama S: [Autopsy case of SCA2 with Parkinsonian phenotype]. Rinsho Shinkeigaku; 2010 Mar;50(3):156-62
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  • HVA and 5-HIAA were reduced in the cerebrospinal fluid, and the heart-mediastinum (H/M) ratio in myocardial 123I-MIBG cintigram was decreased, which suggested Lewy body pathology.

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  • (PMID = 20235484.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Ataxins; 0 / Nerve Tissue Proteins
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80. Vallejo E, Martinez I, Tejero A, Hernandez S, Jimenez L, Bialostozky D, Sanchez G, Ilarraza H, Ferro-Flores G: Clinical utility of 99mTc-labeled ubiquicidin 29-41 antimicrobial peptide for the scintigraphic detection of mediastinitis after cardiac surgery. Arch Med Res; 2008 Nov;39(8):768-74
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  • Semiquantitative analysis showed a higher mediastinum uptake of the (99m)Tc-UBI 29-41 in patients with mediastinitis than that derived from patients without mediastinitis.

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  • (PMID = 18996290.001).
  • [ISSN] 1873-5487
  • [Journal-full-title] Archives of medical research
  • [ISO-abbreviation] Arch. Med. Res.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Antimicrobial Cationic Peptides; 0 / Organotechnetium Compounds; 0 / Peptide Fragments; 0 / technetium 99m ubiquicidin(29-41)
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81. Innasimuthu AL, Rao GK, Wong P: Persistent left-sided superior vena cava--a pacing challenge. Acute Card Care; 2007;9(4):252
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  • After accessing the subclavian vein, the pacing leads were advanced into the LSVC, which was situated to the left of the vertebral column in the mediastinum.

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  • (PMID = 18030627.001).
  • [ISSN] 1748-2941
  • [Journal-full-title] Acute cardiac care
  • [ISO-abbreviation] Acute Card Care
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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82. Oudoux A, Salaun PY, Bournaud C, Campion L, Ansquer C, Rousseau C, Bardet S, Borson-Chazot F, Vuillez JP, Murat A, Mirallié E, Barbet J, Goldenberg DM, Chatal JF, Kraeber-Bodéré F: Sensitivity and prognostic value of positron emission tomography with F-18-fluorodeoxyglucose and sensitivity of immunoscintigraphy in patients with medullary thyroid carcinoma treated with anticarcinoembryonic antigen-targeted radioimmunotherapy. J Clin Endocrinol Metab; 2007 Dec;92(12):4590-7
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  • CONTEXT: Patients with progressive medullary thyroid carcinoma (MTC) undergo multiple imaging procedures for diagnosis of relapse and staging.
  • Sensitivity of FDG-PET/CT was 83% for neck, 85% for mediastinal, 75% for lung, 60% for liver, and 67% for bone metastases; overall sensitivity was 76%.
  • CONCLUSIONS: These results demonstrate the value of FDG-PET/CT for staging of patients with progressive MTC, especially in the neck and mediastinum, with possible prognostication by SUV quantification.
  • [MeSH-major] Carcinoembryonic Antigen / immunology. Carcinoma, Medullary / immunology. Carcinoma, Medullary / radionuclide imaging. Fluorodeoxyglucose F18. Radiopharmaceuticals. Thyroid Neoplasms / immunology. Thyroid Neoplasms / radionuclide imaging

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  • (PMID = 17878252.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Carcinoembryonic Antigen; 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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83. Graham PH, Clark C, Abell F, Browne L, Capp A, Clingan P, De Sousa P, Fox C, Links M: Concurrent end-phase boost high-dose radiation therapy for non-small-cell lung cancer with or without cisplatin chemotherapy. Australas Radiol; 2006 Aug;50(4):342-8
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  • For those who had the mediastinum included in the volume, grade > or = 3 oesophagitis occurred in 0, 11 and 22% (n = 110, P = 0.001), respectively, for treatment groups 1-3.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radiotherapy. Lung Neoplasms / radiotherapy


84. Tubbs RS, Frykman PK, Harmon CM, Oakes WJ, Wellons JC 3rd: An unusual sequelae of an infected persistent dermal sinus tract. Childs Nerv Syst; 2007 May;23(5):569-71
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  • Subsequent lower extremity pain resulted in imaging studies that revealed a spinal mass with extension into the posterior mediastinum.
  • To our knowledge, this is the first reported case of an infected dermal sinus tract with extension into the posterior mediastinum.
  • [MeSH-minor] Bacteroides Infections / etiology. Bacteroides Infections / microbiology. Epidural Abscess / pathology. Fever of Unknown Origin / diagnosis. Fever of Unknown Origin / microbiology. Hemangioma / complications. Hemangioma / pathology. Humans. Infant. Magnetic Resonance Imaging. Male. Mediastinal Diseases / pathology. Spine / diagnostic imaging. Staphylococcal Infections / etiology. Staphylococcal Infections / microbiology. Tomography, X-Ray Computed

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  • [Cites] Pediatr Infect Dis. 1983 Sep-Oct;2(5):385-7 [6634468.001]
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  • (PMID = 16944171.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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85. Frickmann H, Jungblut S, Motherby H, Bargon J: [Gastrointestinal tuberculosis as the main manifestation of systemic tuberculosis]. Pneumologie; 2006 Nov;60(11):667-71
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  • Tissue samples were taken from the mucosa of the colon, the inflammatory altered peritoneum, the left bronchus of the upper lobe and the confluating lymphoid nodes in the mediastinum during colonoscopy, diagnostic laparoscopy and bronchoscopy.
  • Mycobacterium tuberculosis was detected by PCR in the tissue samples from the lymphoid tissue of the mediastinum.

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  • [CommentIn] Pneumologie. 2007 Mar;61(3):170 [17419101.001]
  • (PMID = 17109264.001).
  • [ISSN] 0934-8387
  • [Journal-full-title] Pneumologie (Stuttgart, Germany)
  • [ISO-abbreviation] Pneumologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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86. Tomita H, Matsubayashi H, Sasaki K, Takizawa K, Ikehara H, Kakushima N, Tanaka M, Yamaguchi Y, Ono H: [A case of autoimmune pancreatitis accompanied with Mikulicz's disease]. Nihon Shokakibyo Gakkai Zasshi; 2010 May;107(5):775-83
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  • She was given a diagnosis of autoimmune pancreatitis because of a marked elevation of serum IgG and IgG4 levels and diffuse swelling of the pancreas with stenosis of the main pancreatic duct.
  • Biopsy obtained from the lachrymal gland revealed aggregated IgG4-positive plasma cells, leading to the diagnosis of Mikulicz's disease.
  • PET-CT revealed an accumulation of FDG in the pancreas, lachrymal glands and submandibular glands, and lymph nodes in the mediastinum, hepatic hilium, bile duct and retroperitoneum.

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  • (PMID = 20460852.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 20
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87. Chatti-Dey S, Saïji E, Zidi-Mouaffak Y, Ben Brahim-Negra E, Ben Slimane S, Tangour M, Meddeb N, Maamouri M: [Primary synovialosarcoma: a case of unusual location]. Tunis Med; 2008 Oct;86(10):921-3
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  • Various explorations carried out, in particular thoracic scanner and imagery by magnetic resonance, showed a multilocular cystic formation of the seat and the clavicle reaching the mediastinum.
  • This diagnosis was validated by the immunohistochemistry study and the detection of transcribed specific fusion of the synovialosarcoma, SYT-SSX1.
  • CONCLUSION: The unusual locations of the primitive SS must be known because the diversity of their microscopic aspects may cause confusion in the diagnosis.
  • The immunohistochemistry, and more recently the cytogenetic studies, helps to solve these problems of differential diagnosis.
  • [MeSH-major] Sarcoma, Synovial / pathology. Soft Tissue Neoplasms / pathology. Thoracic Neoplasms / pathology

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  • (PMID = 19472813.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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88. Ngernsritrakul T, Sathirapanya P: Type A aortic dissection presenting as acute ischemic stroke caution for thrombolytic therapy: a case report and literatures review. J Med Assoc Thai; 2008 Aug;91(8):1302-7
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  • Initial chest x-ray revealed widening of the mediastinum.
  • [MeSH-major] Aortic Aneurysm, Thoracic / diagnosis. Brain Ischemia / diagnosis. Fibrinolytic Agents / adverse effects. Stroke / diagnosis

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  • (PMID = 18788707.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Fibrinolytic Agents
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89. Lee PH, Kim JW, Bang OY, Joo IS, Yoon SN, Huh K: Cardiac 123I-MIBG scintigraphy in patients with essential tremor. Mov Disord; 2006 Aug;21(8):1235-8
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  • The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001).
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Female. Heart Diseases / epidemiology. Heart Diseases / radionuclide imaging. Humans. Male. Middle Aged. Radiopharmaceuticals

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  • [Copyright] (c) 2006 Movement Disorder Society
  • (PMID = 16671077.001).
  • [ISSN] 0885-3185
  • [Journal-full-title] Movement disorders : official journal of the Movement Disorder Society
  • [ISO-abbreviation] Mov. Disord.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals; 35MRW7B4AD / 3-Iodobenzylguanidine
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90. Agarwal G, Kar DK: Teratoma of the anterior mediastinum presenting as a cystic neck mass: a case report. J Med Case Rep; 2008;2:23
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  • [Title] Teratoma of the anterior mediastinum presenting as a cystic neck mass: a case report.
  • INTRODUCTION: Teratomas of anterior mediastinum are rare tumors and are often slow growing, asymptomatic and detected incidentally on chest imaging.
  • The mediastinal structures did not show any features of compression or infiltration.
  • In view of the extent and uncertain pathological nature of the tumor, it was excised via a combined cervical and trans-sternal route.
  • Histo-pathology of the resected specimen confirmed the diagnosis of a mature cystic teratoma.
  • We discuss the role of imaging and the need for surgical treatment to avoid possible catastrophic complications in patients with cervical and mediastinal masses of uncertain histological nature.
  • CONCLUSION: A mediastinal teratoma may rarely present as a cystic neck swelling due to its cephalad extension.

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  • (PMID = 18221571.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2259367
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91. Shinkawa T, Nakajima M, Kishimoto T, Inagaki J, Park YD, Kushibe K, Taniguchi S, Nakagawa A, Yoshioka A: A case of idiopathic sclerosing mediastinitis in a 7-year-old Japanese boy. Eur J Pediatr; 2005 May;164(5):302-5
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  • Sclerosing mediastinitis is a very rare benign disorder characterised by the development of dense fibrous tissue within the mediastinum.
  • 67Ga-scintigraphy demonstrated an accumulation in the mediastinal region and an open biopsy revealed a hard fibrous mass in the anteriosuperior mediastinum.
  • Thus, a diagnosis of idiopathic sclerosing mediastinitis was made.
  • CONCLUSION: To the best of our knowledge, this case is the youngest patient reported with this disorder.
  • In patients with mediastinal mass lesions the diagnosis of sclerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.
  • [MeSH-major] Mediastinitis / diagnosis. Mediastinum / pathology

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  • (PMID = 15726406.001).
  • [ISSN] 0340-6199
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Immunoglobulin G; 9007-41-4 / C-Reactive Protein
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92. Kang N, Chung JW, Jung SN: Rare location of Castleman disease in the temporal region. J Craniofac Surg; 2009 May;20(3):830-2
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  • It occurs mainly in the mediastinum but rarely in the face.
  • [MeSH-major] Giant Lymph Node Hyperplasia / diagnosis. Muscular Diseases / diagnosis. Temporal Muscle / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Follow-Up Studies. Humans. Lymphocytes / pathology. Male. Tomography, X-Ray Computed

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  • (PMID = 19349907.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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93. Challapalli A, Howell L, Farrier M, Kelsey A, Birch J, Eden T: Cervical paraganglioma--a case report and review of all cases reported to the Manchester Children's Tumour Registry 1954-2004. Pediatr Blood Cancer; 2007 Jan;48(1):112-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervical paraganglioma--a case report and review of all cases reported to the Manchester Children's Tumour Registry 1954-2004.
  • Seven years later he developed recurrent symptoms and was found to have a recurrence in the anterior mediastinum.
  • We also report on all cases of cervical paragangliomas registered with the Manchester Children's Tumour Registry (MCTR) for the 50-year period 1954-2004.
  • Paragangliomas are very rare tumours in the head and neck but should be considered in the differential diagnosis of neck masses especially when presenting with Horner syndrome.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Mediastinal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Paraganglioma / surgery. Registries
  • [MeSH-minor] Adolescent. Child. Diagnosis, Differential. Female. Humans. Infant. Male

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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16767719.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 34
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94. Shami VM, Waxman I: Technology insight: Current status of endoscopic ultrasonography. Nat Clin Pract Gastroenterol Hepatol; 2005 Jan;2(1):38-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In addition, new non-gastrointestinal applications are being evaluated, such as the role of EUS-FNA for the staging of non-small-cell lung cancer and exploration of the posterior mediastinum.
  • [MeSH-major] Endosonography. Gastrointestinal Neoplasms / ultrasonography
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Neoplasm Staging / methods. Neoplasm Staging / trends

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  • (PMID = 16265099.001).
  • [ISSN] 1743-4378
  • [Journal-full-title] Nature clinical practice. Gastroenterology & hepatology
  • [ISO-abbreviation] Nat Clin Pract Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 67
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95. Machała W, Smiechowicz K, Gaszyński T: [Severe sepsis as a complication of descending necrotizing mediastinitis due to a peritonsillar abscess. A case study]. Otolaryngol Pol; 2006;60(2):211-5
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  • The process originally placed in the peritonsillar area spreads along the cervical fascia engulfs mediastinum.
  • Inflammatory process of the mediastinum considerably worsens the prognosis and obligates to decisive surgical (mediastinum drainage) and pharmacological (antibiotic therapy) treatments.
  • The administration of the treatment within 48 days of hospitalization (antibiotic therapy, thoracotomy, flow drainage of the mediastinum, tracheotomy, respirotherapy) brought about the effect of complete recovery.
  • [MeSH-major] Mediastinitis / microbiology. Mediastinum / pathology. Peritonsillar Abscess / microbiology. Sepsis / microbiology

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  • (PMID = 16903340.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Anti-Infective Agents
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96. Cakir E, Demirag F, Gulhan E, Oz G, Tastepez I: Mediastinal composite hemangioendothelioma. A rare tumor at an unusual location. Tumori; 2009 Jan-Feb;95(1):98-100
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  • [Title] Mediastinal composite hemangioendothelioma. A rare tumor at an unusual location.
  • Composite hemangioendothelioma is a rare vascular tumor; only 12 cases have been previously described in the extremities, tongue and axilla.
  • We report the first case of composite hemangioendothelioma of the mediastinum in a 50-year-old woman.
  • Her chest roentgenogram and computed tomography showed a 6 x 4 x 3 cm mass in the middle mediastinum compressing the trachea.
  • This case is presented not only for the rarity of the tumor type but also for its unusual location.
  • [MeSH-major] Hemangioendothelioma / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 19366065.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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97. Gallego J, Cruz J, Mendes S, Caldeira J, Nobre A, Cravino J: [Surgery of mediastinal tumors: 11-years experience]. Rev Port Cir Cardiotorac Vasc; 2005 Apr-Jun;12(2):73-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgery of mediastinal tumors: 11-years experience].
  • [Transliterated title] Cirurgia dos tumores do mediastino: experiência de 11 anos.
  • Between 1993 and 2004, 70 operations on patients with the diagnosis of mediastinal tumors were performed in the Cardiothoracic Surgery Department of Santa Maria Hospital.
  • In this study we did not include diagnostic surgery of mediastinal tumors.
  • In 70 patients treated, 63 p (90%) had the tumor located in the anterior mediastinum, 21 p with thymoma, 6 p with lymphoma, 4 p with carcinoid tumors, 1 p with sarcoma and 1 p with adenocarcinoma.
  • 3 patients had tumors located in the medium and 4 patients in the posterior mediastinum.
  • We analysed the results of the mediastinal tumors surgery during the 11-years period.
  • [MeSH-major] Mediastinal Neoplasms / surgery
  • [MeSH-minor] Carcinoid Tumor / surgery. Female. Humans. Lymphoma / surgery. Male. Retrospective Studies. Thymoma / pathology. Thymoma / surgery. Thymus Neoplasms / pathology. Thymus Neoplasms / surgery

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  • (PMID = 16077878.001).
  • [ISSN] 0873-7215
  • [Journal-full-title] Revista portuguesa de cirurgia cardio-torácica e vascular : órgão oficial da Sociedade Portuguesa de Cirurgia Cardio-Torácica e Vascular
  • [ISO-abbreviation] Rev Port Cir Cardiotorac Vasc
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
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98. Marini C, Bandettini di Poggio M, Pomposelli E, Marchese R, Nobili F, Morbelli SD, Villa G, Abbruzzese G, Sambuceti G: Whole body and cardiac metaiodobenzylguanidine kinetics in Parkinson disease and multiple system atrophy: implications for the diagnostic role of imaging. Clin Nucl Med; 2010 May;35(5):311-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE OF THE REPORT: This study investigates whether combined analysis of I-123 metaiodobenzylguanidine (MIBG) kinetics in the heart and in the whole body can improve the accuracy of differential diagnosis between idiopathic Parkinson disease (PD) and a Parkinson variant of multiple system atrophy (MSA-P).
  • Final diagnosis was confirmed at follow-up.
  • Myocardial uptake was evaluated by measuring heart/mediastinum (H/M) ratio and the percent fraction of the injected dose retained by the heart (calculated by whole-body counts).
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Injections, Intravenous. Kinetics. Male. Middle Aged

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  • (PMID = 20395701.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 35MRW7B4AD / 3-Iodobenzylguanidine
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99. Tartaglia F, Salvatori FM, Pichelli D, Sgueglia M, Blasi S, Custureri F: Preoperative embolization of thyroid arteries in a patient with a large cervicomediastinal hyperfunctioning goiter. Thyroid; 2007 Aug;17(8):787-92
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  • The preoperative computed tomographic (CT) scan showed the right thyroid lobe very deeply rooted in the mediastinum, below the horizontal plane passing through the aortic arch.
  • [MeSH-minor] Angiography. Combined Modality Therapy. Humans. Male. Mediastinum / radiography. Mediastinum / surgery. Middle Aged. Neck / radiography. Neck / surgery. Preoperative Care. Tomography, X-Ray Computed

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  • (PMID = 17725437.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Gorschlüter M, Mey U, Glasmacher A, Schwerdtfeger R, Schmidt-Wolf IG: Acute myeloid leukemia with near-triploid karyotype and extramedullary involvement of mediastinum. Bone Marrow Transplant; 2005 Dec;36(12):1107
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acute myeloid leukemia with near-triploid karyotype and extramedullary involvement of mediastinum.
  • [MeSH-major] Karyotyping / methods. Leukemia, Myeloid, Acute / genetics. Mediastinal Neoplasms / genetics. Mediastinum / pathology. Polyploidy

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  • (PMID = 16247438.001).
  • [ISSN] 0268-3369
  • [Journal-full-title] Bone marrow transplantation
  • [ISO-abbreviation] Bone Marrow Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 04079A1RDZ / Cytarabine; 6PLQ3CP4P3 / Etoposide; ZRP63D75JW / Idarubicin
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