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1. Unroe MA, Shofer SL, Wahidi MM: Training for endobronchial ultrasound: methods for proper training in new bronchoscopic techniques. Curr Opin Pulm Med; 2010 Jul;16(4):295-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE OF REVIEW: The field of pulmonary medicine has experienced a rapid growth in innovative new technologies aimed at both diagnosis and treatment of airway, mediastinal and parenchymal disorders.
  • Endobronchial ultrasound (EBUS) has emerged as an extremely useful tool in real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures.
  • A growing body of evidence has demonstrated the efficacy of EBUS-TBNA in the diagnosis and staging of lung cancer, as well as the diagnosis of benign causes of mediastinal and hilar lymphadenopathy.
  • This has increased the demand for EBUS among general pulmonologists and thoracic surgeons and is presenting a challenge in establishing teaching venues and training guidelines to gain competence in EBUS.
  • SUMMARY: Evidence-based protocols for teaching EBUS-guided TBNA and other advanced bronchoscopic procedures are necessary as these technologies continue to expand into general pulmonary practice.
  • [MeSH-major] Bronchoscopy / standards. Education, Medical / methods. Endosonography / standards. Pulmonary Medicine / education. Respiratory Tract Diseases / ultrasonography. Ultrasonography, Interventional / standards
  • [MeSH-minor] Biopsy, Needle / standards. Clinical Competence. Computer Simulation. Evidence-Based Medicine. Humans. Lymph Nodes / pathology. Neoplasm Staging. Teaching / methods

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  • (PMID = 20531196.001).
  • [ISSN] 1531-6971
  • [Journal-full-title] Current opinion in pulmonary medicine
  • [ISO-abbreviation] Curr Opin Pulm Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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2. Hofman MS, Smeeton NC, Rankin SC, Nunan T, O'Doherty MJ: Observer variation in FDG PET-CT for staging of non-small-cell lung carcinoma. Eur J Nucl Med Mol Imaging; 2009 Feb;36(2):194-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Error and variation in reporting remains one of the weakest features of clinical imaging despite enormous technological advances in nuclear medicine and radiology.
  • Individual mediastinal lymph node stations were assessed as benign/inflammatory, equivocal or malignant, and AJCC N and M stage were also assigned.
  • RESULTS: Both intra- and interobserver agreement for N and M staging were high.
  • For M staging there was almost perfect intra- and interobserver agreement (kappa = 0.90-0.93).
  • For N staging, agreement was either almost perfect or substantial (intraobserver kappa(w) = 0.79, 0.91; interobserver kappa(w) = 0.75-0.81).
  • Agreement for inferior and superior mediastinal nodes (stations 1, 2, 3, 7, 8, 9) was either almost perfect or substantial (kappa(w) = 0.71-0.88), but lower for hilar nodes (10; kappa(w) = 0.56-0.71).
  • Interreporter variability was greatest for aortopulmonary nodes (5, 6; kappa(w) = 0.48-0.55).
  • CONCLUSION: Amongst experienced reporters in a single centre, there was a very high level of agreement for both mediastinal nodal stage and detection of distant metastases with PET-CT.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnosis. Carcinoma, Non-Small-Cell Lung / pathology. Fluorodeoxyglucose F18. Neoplasm Staging / methods. Positron-Emission Tomography / statistics & numerical data. Tomography, X-Ray Computed / statistics & numerical data
  • [MeSH-minor] Humans. Neoplasm Metastasis. Observer Variation. Referral and Consultation

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  • (PMID = 18828012.001).
  • [ISSN] 1619-7089
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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3. Mercier GA, Alavi A, Fraker DL: FDG positron emission tomography in isolated limb perfusion therapy in patients with locally advanced melanoma: preliminary results. Clin Nucl Med; 2001 Oct;26(10):832-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Eighty lesions (74 malignant, 6 benign) were detected with FDG PET and the SP combined.
  • The six benign lesions included three false-positive mediastinal lymph nodes in one patient.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Antineoplastic Agents, Alkylating / therapeutic use. Chemotherapy, Cancer, Regional Perfusion / methods. Fluorodeoxyglucose F18. Melanoma / drug therapy. Melanoma / radionuclide imaging. Melphalan / therapeutic use. Radiopharmaceuticals. Tomography, Emission-Computed / methods. Tumor Necrosis Factor-alpha / therapeutic use
  • [MeSH-minor] Adult. Aged. Drug Therapy, Combination. Female. Humans. Image Processing, Computer-Assisted. Likelihood Functions. Male. Middle Aged. Neoplasm Metastasis / radionuclide imaging. Sensitivity and Specificity. Whole-Body Counting

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  • (PMID = 11564919.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32CA65442-01A2
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antineoplastic Agents, Alkylating; 0 / Radiopharmaceuticals; 0 / Tumor Necrosis Factor-alpha; 0Z5B2CJX4D / Fluorodeoxyglucose F18; Q41OR9510P / Melphalan
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