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Items 1 to 28 of about 28
1. Vandergriff TW, Reed JA, Orengo IF: An unusual presentation of atypical fibroxanthoma. Dermatol Online J; 2008;14(1):6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atypical fibroxanthoma (AFX) is a rare cutaneous spindle-cell neoplasm.
  • The tumor occurs most commonly in sun-damaged skin of the head and neck in elderly patients.
  • We report an unusual case of AFX of the lower leg in an 81-year-old woman with extensive actinic damage.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Female. Humans. Lower Extremity / pathology

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  • (PMID = 18319023.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Liao KS, Huang WT, Yang SF, Chien SH, Hsieh TJ, Chai CY, Wu CC: Intramuscular low-grade fibromyxoid sarcoma: a case report. Kaohsiung J Med Sci; 2009 Aug;25(8):448-54

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Low-grade fibromyxoid sarcoma (LGFMS) is a rare neoplasm that commonly arises in the deep soft tissues of the lower extremities, particularly in the thigh.
  • Although LGFMS has a deceptively benign histologic appearance, local recurrence and late metastases have frequently been reported.
  • Diagnosis of LGFMS is still difficult because of its characteristic bland-looking histologic features that can be confused with other benign or low-grade fibromyxoid lesions.
  • We report a 29-year-old female who presented with a LGFMS located in the soleus muscle of her left lower leg.

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  • (PMID = 19605340.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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3. Ko JY, Kim JE, Kim YH, Ro YS: Cutaneous plexiform schwannomas in a patient with neurofibromatosis type 2. Ann Dermatol; 2009 Nov;21(4):402-5

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  • Plexiform schwannoma is a rare benign neoplasm of the neural sheath characterized by a multinodular plexiform growth pattern.
  • The tumor usually occurs as an isolated finding, although rare cases have been reported in association with neurofibromatosis type 2 (NF2).
  • His medical history included local excision of a plexiform schwannoma on his left leg in our dermatology clinic 6 years prior.

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  • (PMID = 20523833.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861261
  • [Keywords] NOTNLM ; Neurofibromatosis type 2 / Plexiform / Schwannoma
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4. King R, Googe PB, Page RN, Mihm MC Jr: Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ. Mod Pathol; 2005 Aug;18(8):1043-7
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  • There were nine females and five males ranging in age from 30 to 64 years and anatomic sites included back (five), arm (six), flank (two), and leg (one).
  • Melanocytic neoplasia may appear in association with dermatofibromas.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanocytes / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, Neoplasm. Factor XIIIa / analysis. Female. Humans. Immunohistochemistry. MART-1 Antigen. Male. Melanoma / metabolism. Melanoma / pathology. Middle Aged. Neoplasm Proteins / analysis. Nevus / metabolism. Nevus / pathology. Proto-Oncogene Proteins c-kit / analysis. S100 Proteins / analysis

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  • (PMID = 15803191.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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5. Avninder S, Ramesh V, Vermani S: Benign nerve sheath myxoma (myxoid neurothekeoma) in the leg. Dermatol Online J; 2007;13(2):14
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  • [Title] Benign nerve sheath myxoma (myxoid neurothekeoma) in the leg.
  • Myxoid neurothekeoma is a rare benign cutaneous neoplasm of nerve sheath origin and is also called as benign nerve sheath myxoma.
  • This entity is seen in head, neck and upper extremity and seldom on the lower limb.
  • A myxoid neurothekeoma in the lower leg of a 33-year-old woman is described.
  • [MeSH-major] Lower Extremity. Neurothekeoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17498433.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. El Ibrahimi A, Daoudi A, Znati K, Elmrini A, Boutayeb F: [Insulated leg pilomatrixoma: a rare localization]. Ann Chir Plast Esthet; 2009 Aug;54(4):388-91
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  • [Title] [Insulated leg pilomatrixoma: a rare localization].
  • [Transliterated title] Pilomatricome isolé de la jambe. Une rare localisation.
  • Pilomatrixoma is a benign skin neoplasm of the hair follicle.
  • Through an observation of a pilomatrixoma of the leg in an adult patient treated surgically without recurrence, different diagnostic and therapeutic aspects of this pathology will be recalled.
  • [MeSH-major] Hair Diseases. Leg. Pilomatrixoma. Skin Neoplasms

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  • (PMID = 19195758.001).
  • [ISSN] 1768-319X
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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7. Collina G, Reggiani C: Recurrence of nevoid melanoma originally diagnosed as benign nevus. Pathologica; 2009 Jun;101(3):112-4
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  • [Title] Recurrence of nevoid melanoma originally diagnosed as benign nevus.
  • We report the case of a 27 year-old woman who had a pigmented lesion in her left leg in 2004.
  • [MeSH-major] Melanoma / pathology. Neoplasm Recurrence, Local / pathology. Nevus, Intradermal / diagnosis. Skin Neoplasms / pathology

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  • (PMID = 19886544.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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8. Ramirez RN, Otsuka NY, Apel DM, Bowen RE: Desmoid tumor in the pediatric population: a report of two cases. J Pediatr Orthop B; 2009 May;18(3):141-4
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  • [Title] Desmoid tumor in the pediatric population: a report of two cases.
  • Desmoid tumors are benign tumors that cause considerable morbidity and are prone to recurrence.
  • We present the report of two cases of desmoid tumor in the pediatric population.
  • The first patient had tumor that necessitated removal of most of the anterior compartment of his leg.
  • The tumor in the second case was intimately involved with neurovascular structures and, therefore adjuvant treatment including chemotherapy and repeat surgery was necessary.
  • [MeSH-minor] Child. Combined Modality Therapy. Humans. Infant. Leg / surgery. Male. Neoplasm Recurrence, Local. Tendon Transfer. Treatment Outcome

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  • (PMID = 19322113.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Manduch M, Oliveira AM, Nascimento AG, Folpe AL: Massive localised lymphoedema: a clinicopathological study of 22 cases and review of the literature. J Clin Pathol; 2009 Sep;62(9):808-11
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  • Most lesions involved the thigh, but also occurred in the posterior calf and lower leg.
  • Clinically, most lesions were regarded as representing benign processes, including pedunculated lipoma, lymphocoele or recurrent cellulites, although soft tissue sarcoma was also suspected in two cases.
  • Multinucleated fibroblastic cells, marked vascular proliferation, moderate stromal cellularity and fascicular growth raised concern among referring pathologists for atypical lipomatous tumour/well differentiated liposarcoma, angiosarcoma, and a fibroblastic neoplasm such as fibromatosis in 10, 2 and 1 case, respectively.
  • [MeSH-minor] Adult. Aged. Cellulitis / diagnosis. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Leg / pathology. Lipoma / diagnosis. Lymphocele / diagnosis. Male. Middle Aged. Obesity, Morbid / complications. Retrospective Studies. Sarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 19734477.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 23
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12. Garrido-Ruiz MC, Carrillo R, Enguita AB, Peralto JL: Signet-ring cell dermatofibroma. Am J Dermatopathol; 2009 Feb;31(1):84-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dermatofibroma or cutaneous fibrous histiocytoma is a common benign skin lesion with multiple, distinct histologic variants, including cellular, aneurismal, epithelioid, atypical, lipidized "ankle-type," palisading, and cholesterotic.
  • Although dermatofibromas are considered benign neoplasms, certain variants including cellular and aneurismal ones have shown to have a notable tendency to locally recur after excision.
  • The finding of signet-ring cells in a skin neoplasm always raises the suspicion of metastatic adenocarcinoma, although a number of reports have shown their occurrence in primitive cutaneous neoplasms as well.
  • We present, for the first time, a new, distinctive variant of dermatofibroma, so-called signet-ring cell dermatofibroma, in a 16-year-old man with a slowly growing skin tumor on the lateral side of his right leg.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19155733.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Requena L, Luis Díaz J, Manzarbeitia F, Carrillo R, Fernández-Herrera J, Kutzner H: Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases. J Cutan Pathol; 2008 Feb;35(2):225-30
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  • The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas).
  • The latter is a vascular neoplasm showing varying combinations of benign, low-grade malignant and malignant vascular components.
  • The neoplasm showed a more aggressive behavior than other reported cases of composite hemangioendothelioma and it developed satellitosis and metastases to the inguinal lymph nodes.
  • [MeSH-major] Foot Diseases / pathology. Hemangioendothelioma / pathology. Leg / pathology. Lymphatic Metastasis / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Homeodomain Proteins / metabolism. Humans. Immunohistochemistry. Male. Middle Aged. Tumor Suppressor Proteins / metabolism

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  • (PMID = 18190450.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Tumor Suppressor Proteins; 0 / prospero-related homeobox 1 protein
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14. Hod N, Levi Y, Fire G, Cohen I, Ayash D, Somekh M, Horne T: Scintigraphic characteristics of non-ossifying fibroma in military recruits undergoing bone scintigraphy for suspected stress fractures and lower limb pains. Nucl Med Commun; 2007 Jan;28(1):25-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scintigraphic characteristics of non-ossifying fibroma in military recruits undergoing bone scintigraphy for suspected stress fractures and lower limb pains.
  • INTRODUCTION: Non-ossifying fibroma (NOF) is the most common fibrous bone lesion in children and young adults.
  • This benign lesion is not a true neoplasm but is considered a developmental defect.
  • NOF that ossify can show increased uptake on bone scintigraphy.
  • AIM: To document the scintigraphic features of NOF in a group of military recruits undergoing bone scintigraphy for suspected stress fractures.
  • MATERIALS AND METHODS: Eighty-three military recruits, 67 male and 16 female, aged 18 to 22 years (mean, 19.4 years), who underwent Tc-methylene diphosphonate bone scans for suspected stress fractures or because of pain of the lower limbs had 91 focal lesions on bone scan which on further evaluation demonstrated characteristic radiographic findings of NOF.
  • We evaluated the anatomical site of the lesions, documented the intensity of uptake on bone scan and compared the findings with the radiographic description of the lesions.
  • All the NOF showed variable degrees of focal increased tracer uptake on bone scan.
  • The bone scan appearance of the focal lesions was: faint uptake in 29 (31.9%), mild uptake in 27 (29.7%), moderate uptake in 28 (30.7%) and intensely increased uptake in seven (7.7%).
  • CONCLUSIONS: Military recruits undergoing bone scan for suspected stress fracture might have incidental findings which require further evaluation.
  • Focal lesions on bone scan located about the knee in the lateral aspect of the distal femur or lateral aspect of the proximal tibia in the metaphyseal region of these bones are not compatible with the characteristic scintigraphic features of stress fracture.
  • During the healing phase of the NOF which commonly occur in the age range of this group, the lesion shows mild-to-moderate increased tracer uptake on bone scan.
  • Some NOF lesions are still indistinguishable from stress fracture or splints on bone scan.
  • [MeSH-minor] Adolescent. Adult. Bone Diseases, Developmental / radiography. Bone and Bones / pathology. Female. Humans. Leg Bones / pathology. Male. Military Personnel. Pain. Radiopharmaceuticals / pharmacology. Technetium / pharmacology

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  • (PMID = 17159546.001).
  • [ISSN] 0143-3636
  • [Journal-full-title] Nuclear medicine communications
  • [ISO-abbreviation] Nucl Med Commun
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 7440-26-8 / Technetium
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15. de Koning HD, Bovenschen HJ: Two adjacent nodules on the leg. Dermatol Online J; 2010;16(6):13

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  • [Title] Two adjacent nodules on the leg.
  • Poroma is a rare benign neoplasm (derived from the intraepidermal part of the eccrine or apocrine duct), which may clinically mimic malignant tumors such as (amelanotic) malignant melanoma and porocarcinoma.
  • Despite a clinical differential diagnosis of melanoma, histopathology showed the typical characteristics of a poroma, a rare but much more favorable tumor.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Leg. Poroma / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 20579468.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Ech-Cherif El Kettani N, Nassar I, Bouklata S, Hammani L, Kabbaj N, Gueddari FZ, Lola N, Ajana A, Imani F: [Glomus tumor of the leg: a case report]. J Radiol; 2005 May;86(5 Pt 1):493-5

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  • [Title] [Glomus tumor of the leg: a case report].
  • [Transliterated title] A propos d'une tumeur glomique de la jambe.
  • Glomus tumor is an uncommon benign neuromyoarterial tumor.
  • The clinical, imaging and therapeutic considerations regarding a glomangioma of the leg in a 65-year-old-man are reviewed.
  • [MeSH-major] Glomus Tumor / radiography. Leg / radiography. Soft Tissue Neoplasms / radiography
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Recurrence, Local / radiography. Tomography, X-Ray Computed

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  • (PMID = 16114206.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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17. Plesinac-Karapandzic V, Perisic Z, Milovanovic Z, Vukicevic D, Mileusnic D, Stevanovic J, Rakocevic Z, Saric M: Invasive inflammatory pseudotumor of the pelvis: a case report with review of the literature. J BUON; 2009 Apr-Jun;14(2):301-6

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  • Inflammatory pseudotumor (IPT) is a rare benign lesion of unknown etiology, which mimics malignant neoplasm and may arise from various organs.
  • A 53-year-old woman was submitted to diagnostic evaluation because of bilateral, hydroureteronephrosis and oedema of the left leg after a 3-month history of fever of unknown origin.
  • The last follow-up CT, 20 months after laparotomy, revealed no evidence of tumor.

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  • (PMID = 19650182.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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18. Chiang ER, Chen TH: Multiple glomus tumors in gastrocnemius muscle: a case report. Arch Orthop Trauma Surg; 2008 Jan;128(1):29-31

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  • Glomus tumors are rare benign tumors that account 1-5% of soft tissue tumors of the hand.
  • We describe an unusual case of recurrent glomus tumor located in lower leg.
  • [MeSH-major] Glomus Tumor / diagnosis. Muscle Neoplasms / diagnosis. Muscle, Skeletal. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17624538.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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19. Tsubota S, Higaki N, Nagaro T: [A case of neuropathic cancer pain in the lower extremities successfully treated with spinal cord stimulation]. Masui; 2009 Nov;58(11):1460-1
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  • [Title] [A case of neuropathic cancer pain in the lower extremities successfully treated with spinal cord stimulation].
  • A 76-year-old man was referred to our pain clinic for the treatment of bilateral lower extremity pain due to metastasis of renal cell carcinoma to the sacrum.
  • The characteristics of pain were like those of benign disease, being spontaneous, not exacerbated by body movement, and having a dysesthetic nature with chill sensations.
  • This case shows the usefulness of SCS for neuropathic cancer pain that shows signs similar to those of benign disease.
  • [MeSH-minor] Aged. Carcinoma, Renal Cell / pathology. Humans. Kidney Neoplasms / pathology. Leg / innervation. Male. Neoplasm Metastasis

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  • (PMID = 19928521.001).
  • [ISSN] 0021-4892
  • [Journal-full-title] Masui. The Japanese journal of anesthesiology
  • [ISO-abbreviation] Masui
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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20. Brenn T, Fletcher CD: Radiation-associated cutaneous atypical vascular lesions and angiosarcoma: clinicopathologic analysis of 42 cases. Am J Surg Pathol; 2005 Aug;29(8):983-96
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  • Atypical post-radiation vascular lesions (AVLs) with a benign course have been described recently, but few cases with limited follow-up have been studied so far.
  • Presentation ranged from small erythematous/violaceous papules or nodules to large plaques with discoloration located on the chest wall (35), abdomen (2), shoulder, groin, flank, axilla, and lower leg (1 each).
  • No adverse outcome has been observed so far in this more benign subset of cases, but longer-term follow-up is necessary.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Breast Neoplasms / radiotherapy. Female. Follow-Up Studies. Humans. Middle Aged. Neoplasm Recurrence, Local. Neoplasms / radiotherapy. Time Factors

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  • (PMID = 16006792.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Pinto Blázquez J, Velasco Alonso J, Menendez CL, Alonso de la Campa J, Astudillo Gonzalez A: Fine needle aspiration cytology of focal myositis: a case report. Acta Cytol; 2005 Nov-Dec;49(6):653-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is a benign condition and usually involves the muscles of the limbs.
  • CASE: A man presented with a palpable mass in the left leg of 6 months' duration.
  • Nuclear magnetic resonance of the leg showed a mass in the tibial muscle; the presumptive diagnosis was sarcoma of the muscle.
  • CONCLUSION: Focal myositis should always he considered when aspirating muscle masses because it is a clinical mimic of a neoplasm.

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  • (PMID = 16450907.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Campos WK, Linhares MN: Sporadic intramedullary spinal cord hemangioblastoma in a newborn. Pediatr Neurosurg; 2010;46(5):385-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They are highly vascular, benign tumors that occur either sporadically or in the presence of von Hippel-Lindau disease.
  • METHODS: We present a case of a 1-month-old male with a back deformity and left leg hypomotility.
  • MRI of the spine revealed an intramedullary tumor extending from level T6 to T12.
  • RESULTS: The tumor was excised completely, using standard microsurgical techniques via a posterior approach.
  • CONCLUSION: A review of the literature revealed that this neoplasm is composed of 3 major cell types: endothelial cells, pericytes and stromal cells.
  • Complete microsurgical removal is the treatment of choice for spinal cord HB because the tumor is benign.

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  • [Copyright] Copyright © 2011 S. Karger AG, Basel.
  • (PMID = 21389752.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
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23. Fukunaga M, Suzuki K, Saegusa N, Folpe AL: Composite hemangioendothelioma: report of 5 cases including one with associated Maffucci syndrome. Am J Surg Pathol; 2007 Oct;31(10):1567-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Composite hemangioendothelioma (HE) is a low-grade malignant vascular tumor showing varying combinations of benign, low-grade malignant, and malignant vascular components.
  • The tumors arose in the foot or lower leg in 3 patients, in the jaw in 1 patient, and as multiple tumors in the left upper extremity in 1 patient.
  • Two patients had congenital tumors, in the lower thigh and foot, and upper extremity, respectively.
  • Of 4 cases with follow up (median duration, 8.6 y), 1 tumor recurred locally.
  • We conclude that composite HE should continue to be regarded as a low-grade malignant vascular tumor (HE), with significant potential for local recurrence, but little if any potential for distant metastasis.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Female. Humans. Immunoenzyme Techniques. Male. Neoplasm Recurrence, Local

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  • (PMID = 17895759.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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24. Monson E, Vancourt R, Dawson J: Myxoinflammatory fibroblastic sarcoma: a case report and review of the literature. J Foot Ankle Surg; 2010 Jan-Feb;49(1):86.e1-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The majority of soft tissue masses seen in the lower extremity are benign tumors caused by degenerative, reactive, or inflammatory processes.
  • We present a case of a myxoinflammatory fibroblastic sarcoma of the leg and review the literature on this topic.
  • This is a rare tumor that predominately involves the distal extremities.
  • It often presents as a painless mass within the subcutaneous tissue and can easily be confused with benign lesions.
  • A high rate of local recurrence means patients must be followed up closely after resection of the tumor.
  • [MeSH-minor] Amputation. Humans. Leg. Male. Middle Aged. Muscle, Skeletal / pathology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / surgery. Postoperative Complications. Surgical Flaps

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  • [Copyright] Copyright 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20123295.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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25. Yalniz E, Alicioglu B, Yalcin O, Yilmaz B: Non specific magnetic resonance features of chondromyxoid fibroma of the iliac bone. J BUON; 2007 Jul-Sep;12(3):407-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non specific magnetic resonance features of chondromyxoid fibroma of the iliac bone.
  • Chondromyxoid fibroma is a benign cartilaginous neoplasm.
  • The tumor is rare, perhaps the rarest of all bone tumors.
  • We report a case of a 31-year-old woman with chondromyxoid fibroma arising from the iliac bone and presenting with leg pain due to compression on the femoral nerve.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chondroma / diagnosis. Fibroma / diagnosis. Ilium. Magnetic Resonance Imaging

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  • (PMID = 17918298.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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26. Fassina A, Fedeli U, Corradin M, Da Frè M, Fabbris L: Accuracy and reproducibility of pleural effusion cytology. Leg Med (Tokyo); 2008 Jan;10(1):20-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nine pathologists and eight residents from seven institutions in north-east Italy blindly examined 45 smears of MM (17), metastases (14) and benign effusions (14), in two rounds.
  • Diagnostic accuracy, interobserver and intraobserver agreement in the distinction of benign vs malignant cases, and in the differentiation of primary from metastatic malignancies, were evaluated.
  • The distinction of benign from malignant smears resulted rather satisfactory (k=0.514), but markedly decreased in differentiation of MM from metastases (overall agreement: k=0.343), as well as when readings from residents were analyzed (k=0.132).
  • [MeSH-major] Mesothelioma / diagnosis. Neoplasm Metastasis / diagnosis. Pleural Effusion / pathology. Pleural Neoplasms / diagnosis

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  • (PMID = 17702624.001).
  • [ISSN] 1344-6223
  • [Journal-full-title] Legal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Leg Med (Tokyo)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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27. de Wind A, Meert V, Chahidi N, Theunis A, Somerhausen Nde S: [Retiform haemangioendothelioma: a case report]. Ann Pathol; 2009 Dec;29(6):491-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present an additional case, in the leg of a 64-year-old patient.
  • Spindle cell hemangio(endothelio)ma is currently regarded as a benign reactive lesion.
  • The vascular lesions fulfilling the strict definition of hemangioendothelioma include retiform hemangioendothelioma, papillary intralymphatic angioendothelioma "Dabska's tumor", composite hemangioendothelioma and perhaps the controversial polymorphic hemangioendothelioma.
  • [MeSH-minor] Antigens, CD / analysis. Antigens, CD31 / analysis. Antigens, CD34 / analysis. Endothelium, Vascular / pathology. Humans. Male. Middle Aged. Neoplasm Metastasis. Tibia / pathology. Vascular Neoplasms / pathology

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  • (PMID = 20005438.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, CD34
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28. Kok PJ, van Eerd JE, Boerman OC, Corstens FH, Oyen WJ: Biodistribution and imaging of FDG in rats with LS174T carcinoma xenografts and focal Escherichia coli infection. Cancer Biother Radiopharm; 2005 Jun;20(3):310-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The dynamic distribution of FDG was studied in Rowett nude (RNU) rats with a LS174T carcinoma xenograft in the left front leg and an Escherichia coli-induced focal infection in the right front leg.
  • RESULTS: Dynamic positron emission tomography (PET) visualized both the tumor and the infection.
  • The ROI analysis showed that FDG uptake in the infections was faster and higher, as compared to the tumor lesions.
  • FDG uptake in the tumor reached a standardized uptake value (SUV) of 0.8 +/- 0.3 at 60 minutes and in the infectious lesions a SUV of 1.6 +/- 0.2 at 45 minutes, both remaining constant until 4 hours postinjection (p.i.).
  • In the biodistribution study with ex vivo tissue counting, FDG had accumulated up to 1.1 +/- 0.1 %ID/g and 0.8 +/- 0.1 %ID/g at 1 hour in the tumor and infection, respectively, and remained constant until 4 hours for both lesions without significantly different wash-out from the 2 lesions.
  • The tumor/blood and abscess/ blood ratios increased with time to 57 +/- 17 and 48 +/- 14, respectively.
  • CONCLUSION: Although in this model differences in absolute FDG uptake and initial kinetics between tumor and infection were observed, the wash-out rate of FDG from the lesions was similar over time.
  • The retention of FDG in the inflammatory lesion indicated that dual time-point imaging does not necessarily resolve diagnostic pitfalls for FDG-PET in oncology in order to discriminate between malignant tumorous and benign infectious lesions.
  • [MeSH-minor] Animals. Cell Line, Tumor. Escherichia coli / physiology. Humans. Neoplasm Transplantation. Positron-Emission Tomography. Rats. Rats, Nude. Tissue Distribution

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  • (PMID = 15989476.001).
  • [ISSN] 1084-9785
  • [Journal-full-title] Cancer biotherapy & radiopharmaceuticals
  • [ISO-abbreviation] Cancer Biother. Radiopharm.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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