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[Title] Surgical management of 121 benign proximal fibula tumors.

Patients with aggressive benign tumors in the proximal fibula may require en bloc resection.

QUESTIONS/PURPOSES: We therefore analyzed the incidence of peroneal nerve palsy, knee stability, and local recurrence following surgical treatment of benign proximal fibula tumors.

METHODS: We retrospectively reviewed the charts of 120 patients (121 tumors) with histologically confirmed aggressive benign tumors of the proximal fibula.

The most common diagnosis was osteochondroma (38%) followed by giant cell tumor (19%).

[MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Curettage / adverse effects. Female. Humans. Joint Instability / etiology. Joint Instability / physiopathology. Knee Joint / physiopathology. Male. Middle Aged. Neoplasm Recurrence, Local. Osteotomy / adverse effects. Peroneal Neuropathies / etiology. Range of Motion, Articular. Retrospective Studies. Surgical Wound Dehiscence / etiology. Time Factors. Treatment Outcome. Venous Thrombosis / etiology. Young Adult

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(PMID = 20625947.001).

[ISSN] 1528-1132

[Journal-full-title] Clinical orthopaedics and related research

[ISO-abbreviation] Clin. Orthop. Relat. Res.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2947668

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Curettage of benign bone tumors without grafts gives sufficient bone strength.

BACKGROUND AND PURPOSE: The defect that results after curettage of a bone tumor is usually filled in the same way.

We report the outcome in patients with benign bone tumors that were treated with curettage but no filling.

PATIENTS AND METHODS: We retrospectively studied 78 patients (mean age at the time of operation was 27 (6-73) years, 44 men) who had had a benign bone tumor curetted with no filling of the defect.

The commonest tumor types were giant cell tumor of bone (27), fibrous dysplasia (13), enchondroma (9), and simple bone cyst (7).

Local recurrence occurred in 9 patients; 7 of them had a giant cell tumor.

[MeSH-minor] Adolescent. Adult. Aged. Bone Cysts / surgery. Bone Remodeling / physiology. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Humans. Middle Aged. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Treatment Outcome. Young Adult

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[CommentIn] Acta Orthop. 2009 Feb;80(1):2-3 [19297784.001]

(PMID = 19234882.001).

[ISSN] 1745-3682

[Journal-full-title] Acta orthopaedica

[ISO-abbreviation] Acta Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] Sweden

[Other-IDs] NLM/ PMC2823236

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Benign fibro-osseous lesions of the craniofacial complex. A review.

Benign fibro-osseous lesions of the craniofacial complex are represented by a variety of disease processes that are characterized by pathologic ossifications and calcifications in association with a hypercellular fibroblastic marrow element.

The definitive diagnosis can rarely be rendered on the basis of histopathologic features alone; rather, procurement of a final diagnosis is usually dependent upon assessment of microscopic, clinical and imaging features together.

[MeSH-major] Cementoma / diagnosis. Fibroma, Ossifying / diagnosis. Fibrous Dysplasia of Bone / diagnosis. Osteitis Deformans / diagnosis. Skull Neoplasms / diagnosis

[MeSH-minor] DNA, Neoplasm / analysis. Humans. Mutation

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[Cites] Oral Surg Oral Med Oral Pathol. 1993 Nov;76(5):601-7 [8247501.001]

(PMID = 20614314.001).

[ISSN] 1936-0568

[Journal-full-title] Head and neck pathology

[ISO-abbreviation] Head Neck Pathol

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Chemical-registry-number] 0 / DNA, Neoplasm

[Other-IDs] NLM/ PMC2807558

[Keywords] NOTNLM ; Benign fibroosseous lesions / Cementoma / Cementoosseous dysplasia / Fibrous dysplasia / Ossifying fibroma / Osteitis deformans

   

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[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Benign parosteal osteochondromatous proliferation of the hand originally diagnosed as osteochondroma: a report of two cases and review.

Bizarre parosteal osteochondromatous proliferation (BPOP) is a rare cartilaginous neoplasm that often presents in the long bones of the hands and feet.

BPOP is a benign but locally aggressive fibro-osseous mass that has striking clinical, radiographic, and histologic similarities with osteochondroma.

This report presents two cases of BPOP where initial clinical diagnosis of osteochondroma was made even after appropriate imaging and histologic samples were evaluated.

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[Cites] Arch Orthop Trauma Surg. 1990;110(1):58-60 [2288809.001]

[Cites] Skeletal Radiol. 1987;16(6):481-3 [3659995.001]

[Cites] J Bone Joint Surg Am. 1985 Apr;67(4):648-50 [3980514.001]

[Cites] Am J Surg Pathol. 1983 Apr;7(3):245-50 [6837834.001]

[Cites] Skeletal Radiol. 2007 Sep;36(9):829-34 [17437102.001]

[Cites] Skeletal Radiol. 1999 Jan;28(1):1-20 [10068070.001]

[Cites] Skeletal Radiol. 2001 Jan;30(1):44-7 [11289634.001]

[Cites] Eur J Radiol. 2001 Dec;40(3):224-31 [11731211.001]

[Cites] Skeletal Radiol. 2006 Jul;35(7):497-502 [16602017.001]

[Cites] Am J Surg Pathol. 1993 Jul;17(7):691-7 [8317609.001]

(PMID = 19669236.001).

[ISSN] 1558-9455

[Journal-full-title] Hand (New York, N.Y.)

[ISO-abbreviation] Hand (N Y)

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2820629

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System.

Recent modification of the World Health Organization histologic classification and the American Joint Committee on Cancer staging system of adult renal tumors further highlighted the need for case analysis in this age group.

The tumors were reevaluated according to the 2004 World Health Organization classification and the 2002 American Joint Committee on Cancer staging system.

Seventeen percent of these tumors had multilocular cystic features involving more than 50% of the tumor volume (55%-85%).

The number of oncocytomas was also significantly lower in younger adults than in older adults (2% vs 11%, P < .001), and this presumably age-related benign neoplasm was not identified in patients younger than 40 years in this study.

In contrast, the miscellaneous tumor category showed a remarkable increase, from 4% in older adults to 26% in younger adults (P < .001).

Younger female adults tended to have more benign miscellaneous neoplasms than did their male counterparts (64% vs 36%, P < .001).

Malignant and benign renal neoplasms tend to have a contrasting sex distribution in younger adults.

[MeSH-minor] Adult. Age Distribution. Female. Humans. Male. Neoplasm Staging. Sex Distribution

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(PMID = 15794671.001).

[ISSN] 1543-2165

[Journal-full-title] Archives of pathology & laboratory medicine

[ISO-abbreviation] Arch. Pathol. Lab. Med.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Malignant Natural-Killer cell neoplasm presenting as a mucous cyst on the distal interphalangeal joint of the finger.

The analysis revealed the presence of a Natural-Killer cell neoplasm.

This case illustrates and stresses the importance of a pathohistological examination when doubts arise about the initial diagnosis of a benign tumorous lesion.

[MeSH-minor] Aged. Cysts / diagnosis. Fingers. Humans. Male

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(PMID = 19084980.001).

[ISSN] 1434-3916

[Journal-full-title] Archives of orthopaedic and trauma surgery

[ISO-abbreviation] Arch Orthop Trauma Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Chondrosarcoma of the temporomandibular joint: a case report in a child.

This article reports a rare case of a temporomandibular joint (TMJ) chondrosarcoma in a child.

Chondrosarcoma is a malignant cartilaginous neoplasm that resembles synovial chondromatosis.

Microscopic findings showed a tumor exhibiting cartilaginous tissue proliferation with cellular pleomorphism, nuclear hyperchromasia, and mixoid changes in the matrix.

It is concluded that cartilaginous lesions in the jaws must be regarded with suspicion, since benign and malignant lesions may show similar clinical features.

[MeSH-major] Chondrosarcoma / pathology. Temporomandibular Joint Disorders / pathology

[MeSH-minor] Child. Cyclin B / analysis. Cyclin B1. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Mandibular Condyle / pathology. Temporomandibular Joint / pathology

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(PMID = 19639107.001).

[ISSN] 1064-6655

[Journal-full-title] Journal of orofacial pain

[ISO-abbreviation] J Orofac Pain

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / CCNB1 protein, human; 0 / Cyclin B; 0 / Cyclin B1; 0 / Ki-67 Antigen

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution.

From 1975 to 1997, 649 cases of benign giant cell tumours of the bone were treated at the Istituto Rizzoli.

The time interval between the diagnosis and the appearance of the lung metastases ranged from 3 months to 11.9 years.

In contrast to previous reports, we could not detect a predominance of the distal radius, but all of the patients had a stage III tumour according to the Enneking criteria of benign lesions.

We conclude that even metastatic benign giant cell tumours have an excellent prognosis after adequate resection.

[MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology

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[Cites] J Orthop Surg (Hong Kong). 2004 Jun;12(1):55-62 [15237123.001]

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(PMID = 16909252.001).

[ISSN] 0341-2695

[Journal-full-title] International orthopaedics

[ISO-abbreviation] Int Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

[Other-IDs] NLM/ PMC3172731

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Intra-articular recurrence of benign chondroblastoma with articular involvement at initial presentation--a case report.

[MeSH-minor] Adolescent. Curettage. Epiphyses / pathology. Humans. Knee Joint. Male. Neoplasm Recurrence, Local. Neoplasm Seeding. Soft Tissue Neoplasms / pathology

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(PMID = 16981100.001).

[ISSN] 0939-7248

[Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie

[ISO-abbreviation] Eur J Pediatr Surg

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A joint detection of CEA and CA-50 levels in saliva and serum of patients with tumors in oral region and salivary gland.

METHODS: The concentrations of salivary CEA and CA-50 were assayed in 80 patients of oral and salivary malignant tumors, 40 patients of benign tumors and 80 health controls.

RESULTS: Salivary CEA and CA-50 levels were significantly higher in malignant tumors than in benign tumors and in health controls, respectively (P < 0.001).

This may be more useful as prognostic indicators in early diagnosis of oral and salivary malignant tumors.

[MeSH-major] Adenoma / blood. Antigens, Tumor-Associated, Carbohydrate / analysis. Carcinoembryonic Antigen / analysis. Mouth Neoplasms / blood. Saliva / chemistry. Salivary Gland Neoplasms / blood

[MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. Enzyme-Linked Immunosorbent Assay. Female. Humans. Immunoradiometric Assay. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate. Young Adult

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(PMID = 19322585.001).

[ISSN] 1432-1335

[Journal-full-title] Journal of cancer research and clinical oncology

[ISO-abbreviation] J. Cancer Res. Clin. Oncol.

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Germany

[Chemical-registry-number] 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / CA-50 antigen; 0 / Carcinoembryonic Antigen

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Giant cell tumor of bone: a neoplasm or a reactive condition?

Giant cell tumor of bone (GCTB) is a benign but locally aggressive bone tumor of young adults.

Malignancy usually does not occur in GCTB and when discover, it usually represents primary bone sarcomas missed at original diagnosis.

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(PMID = 18787633.001).

[ISSN] 1936-2625

[Journal-full-title] International journal of clinical and experimental pathology

[ISO-abbreviation] Int J Clin Exp Pathol

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2480584

[Keywords] NOTNLM ; Giant cell tumor / aneurysmal bone cyst / bone / bone matrix / hemorrhage / osteoclast / osteoclastoma / telomerase

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report.

OBJECTIVE: This study describes a case of nodular fasciitis involving the hand and reviews the neoplasm's pertinent clinical, histologic, and pathologic features.

CONCLUSIONS: Nodular fasciitis is a self-limited, benign soft tissue tumor composed of fibroblasts and myofibroblasts that typically afflicts younger patients and rarely presents in the hand.

Because of its presentation, it can be easily mistaken for a malignant neoplasm.

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[Cites] Orthop Clin North Am. 2006 Jan;37(1):53-63 [16311111.001]

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(PMID = 18725954.001).

[ISSN] 1937-5719

[Journal-full-title] Eplasty

[ISO-abbreviation] Eplasty

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2491338

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases.

Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis.

Vascular invasion outside the boundary of the tumor can be seen.

Metastasis, with identical morphology to the primary tumor, occurs in a few percent of cases, usually to the lung.

[MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local. Tibia / pathology

MedlinePlus Health Information. consumer health - Bone Cancer.

MedlinePlus Health Information. consumer health - Lung Cancer.

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[Cites] J Bone Miner Res. 2000 Apr;15(4):640-9 [10780856.001]

[Cites] Ann Surg Oncol. 2010 Mar;17(3):694-701 [19902306.001]

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(PMID = 20860830.001).

[ISSN] 1746-1596

[Journal-full-title] Diagnostic pathology

[ISO-abbreviation] Diagn Pathol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Bone Cements

[Other-IDs] NLM/ PMC2954972

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Although most primary bone tumors and soft tissue tumors arise around the knee joint, many patients with tumoral conditions attribute their symptoms to traumatic events.

Arthroscopy is the preferred method for diagnosis and treatment of knee joint disease, but even a minimally invasive procedure may have adverse consequences in the presence of an unsuspected neoplasm.

In addition, arthroscopy is a useful adjunct during surgical treatment of patients with certain juxta-articular benign bone tumors.

In this Current Concepts review, we consider the risks and benefits of arthroscopy in the presence of tumors about the knee joint.

[MeSH-major] Arthroscopy. Bone Neoplasms / surgery. Knee Joint

[MeSH-minor] Biopsy. Humans. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery

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(PMID = 16651168.001).

[ISSN] 1526-3231

[Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

[ISO-abbreviation] Arthroscopy

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 29

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Giant cell tumor of the thumb proximal phalanx: resection-iliac graft and double arthrodesis].

Giant cell tumours (GCT) of bone are frequent, with variable behaviour, high risk of recurrence and an often benign histological appearance.

After a surgical biopsy, we performed an "en bloc" resection of the first phalanx, with an iliac crest graft reconstruction and a double arthrodesis of the metacarpophalangeal and interphalangeal joint.

[MeSH-major] Bone Neoplasms. Giant Cell Tumor of Bone. Thumb

[MeSH-minor] Arthrodesis. Biopsy. Bone Nails. Bone Transplantation. Finger Joint. Follow-Up Studies. Fracture Fixation, Internal / instrumentation. Fractures, Spontaneous / etiology. Fractures, Spontaneous / surgery. Humans. Male. Metacarpophalangeal Joint. Middle Aged. Neoplasm Staging. Patient Satisfaction. Time Factors. Treatment Outcome

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(PMID = 18248835.001).

[ISSN] 1297-3203

[Journal-full-title] Chirurgie de la main

[ISO-abbreviation] Chir Main

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] France

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

METHODS: Two hundred four patients with tumors of the foot and ankle were analyzed (163 benign and 41 malignant).

RESULTS: The most frequent tumors were exostosis, bone cyst, and osteoid osteoma for benign tumors and metastases and chondrosarcoma and Ewing's sarcoma for malignant tumors.

In more than 90% of the benign tumors, local resection could be carried out, whereas in malignant tumors, ablative procedures and arthrodeses were almost as common as limb- and joint-sparing techniques.

[MeSH-major] Ankle Joint / surgery. Bone Neoplasms / surgery. Foot / surgery. Foot Diseases / surgery. Soft Tissue Neoplasms / surgery

[MeSH-minor] Adolescent. Adult. Aged. Amputation. Arthrodesis. Bone Transplantation. Child. Child, Preschool. Female. Follow-Up Studies. Fracture Fixation, Internal. Fractures, Spontaneous / diagnosis. Fractures, Spontaneous / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging. Retrospective Studies

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(PMID = 15526178.001).

[ISSN] 0009-4722

[Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

[ISO-abbreviation] Chirurg

[Language] ger

[Publication-type] English Abstract; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Pigmented villonodular synovitis (PVS) is a benign proliferative disorder of unknown origin that affects synovial joints, most commonly the knee.

The joint knee can be affected by localized or diffuse form.

Although this disease is categorized as an inflammatory process rather than a neoplasm, it may be locally destructive and involve muscles, tendons, bone and skin.

[MeSH-major] Peroneal Neuropathies / diagnosis. Peroneal Neuropathies / etiology. Synovitis, Pigmented Villonodular / complications. Synovitis, Pigmented Villonodular / diagnosis

[MeSH-minor] Humans. Knee Joint / pathology. Knee Joint / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Orthopedic Procedures / methods. Peroneal Nerve / pathology. Peroneal Nerve / surgery

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[Cites] Knee. 2007 Oct;14 (5):390-4 [17600720.001]

[Cites] Arthroscopy. 2001 May;17(5):527-31 [11337722.001]

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[Cites] J Clin Neurosci. 2007 Apr;14 (4):386-8 [17240150.001]

[Cites] Knee. 2007 Mar;14(2):99-106 [17161949.001]

[Cites] Clin Orthop Relat Res. 1996 Apr;(325):174-80 [8998871.001]

(PMID = 19205665.001).

[ISSN] 1433-7347

[Journal-full-title] Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

[ISO-abbreviation] Knee Surg Sports Traumatol Arthrosc

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

That the method employed for achieving that desideratum, which had as its animating force a longing to determine prognosis for an individual patient with that malignant neoplasm, failed miserably can be inferred from the fact that successive efforts every few years by teams of supposed authorities, such as those of the American Joint Committee on Cancer (AJCC), resulted in a new system for staging that bore little resemblance to the one immediately before it or the one that was to come after it.

The job of a pathologist is to render an accurate diagnosis (which, in itself, has implications prognostic for a patient, eg, "benign" or "malignant"), not to speculate about prognosis.

[MeSH-major] Melanoma / history. Melanoma / pathology. Neoplasm Staging / history. Skin Neoplasms / history. Skin Neoplasms / pathology

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(PMID = 15798444.001).

[ISSN] 0193-1091

[Journal-full-title] The American Journal of dermatopathology

[ISO-abbreviation] Am J Dermatopathol

[Language] eng

[Publication-type] Historical Article; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

INTRODUCTION: A synovial chondromatosis is a rare benign neoplasm on the synovium.

Although described as a benign disease, it can be very destructive and can cause severe osteoarthritis and pain.

To the best of our knowledge, we report the first known case of an extensive presentation of this intra-articular and extra-articular disease of the knee joint.

CONCLUSIONS: Although synovial chondromatosis is described as a benign disease, it can be very destructive and debilitating.

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[Cites] J Arthroplasty. 2008 Apr;23(3):395-400 [18358378.001]

[Cites] J Bone Joint Surg Am. 1973 Dec;55(8):1747-8 [4804995.001]

[Cites] J Bone Joint Surg Am. 2007 Jun;89(6):1321-8 [17545437.001]

(PMID = 20416049.001).

[ISSN] 1752-1947

[Journal-full-title] Journal of medical case reports

[ISO-abbreviation] J Med Case Rep

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC2873448

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Pseudogout mimicking an infratemporal fossa tumor.

METHODS AND RESULTS: We present a case of a 71-year-old woman who presented with worsening facial pain, trismus, and a large mass in her infratemporal fossa with minimal associated temporomandibular joint destruction.

CONCLUSION: The clinical and radiological features of patients with tophaceous pseudogout frequently mimic those of a benign or malignant neoplasm of the infratemporal fossa, often resulting in more radical surgery.

[MeSH-major] Chondrocalcinosis / diagnosis. Chondrocalcinosis / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery. Temporal Bone / surgery

[MeSH-minor] Aged. Diagnosis, Differential. Facial Pain / etiology. Female. Humans. Otorhinolaryngologic Surgical Procedures / methods. Temporomandibular Joint / pathology. Treatment Outcome. Trismus / etiology

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(PMID = 19283846.001).

[ISSN] 1097-0347

[Journal-full-title] Head & neck

[ISO-abbreviation] Head Neck

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.

OBJECTIVE: To evaluate functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.

METHODS: Twenty-five patients who underwent Malawer I type resection and reconstruction of the proximal humerus for treatment of malignant or invasive benign tumors from August 1999 to August 2005 were evaluated.

A variety of reconstructive procedures, including modular tumor prosthesis, osteoarticular allograft, and allograft-prosthetic composite (APC), were performed after resection of tumor.

The modified Musculoskeletal Tumor Society (MSTS) evaluation system was used to assess limb functional outcome.

RESULTS: The study group consisted of 10 male and 15 female patients, among which there were 20 malignant and 5 benign tumors.

Joint instability and subluxation were serious complications affecting shoulder function in 10 patients.

[MeSH-major] Arthroplasty, Replacement / methods. Bone Neoplasms / surgery. Humerus / surgery. Neoplasms, Connective Tissue / surgery. Shoulder Joint / surgery

[MeSH-minor] Adolescent. Adult. Child. Female. Humans. Lymphoma / mortality. Lymphoma / pathology. Lymphoma / surgery. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Postoperative Complications / epidemiology. Recovery of Function. Retrospective Studies. Treatment Outcome. Young Adult

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[Copyright] © 2010 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.

(PMID = 22009903.001).

[ISSN] 1757-7861

[Journal-full-title] Orthopaedic surgery

[ISO-abbreviation] Orthop Surg

[Language] eng

[Publication-type] Evaluation Studies; Journal Article

[Publication-country] Australia

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Knee reconstruction with preservation of the meniscus in tibial giant cell tumor.

Giant cell tumor of bone sometimes is an aggressive benign skeletal tumor.

Thus, maintaining joint function and achieving adequately wide resection introduces contradictory surgical goals.

We reconstructed 13 knees preserving the meniscus and reconstructing the tibial plateau with an iliac plate autograft after resection of a giant cell tumor involving one tibial plateau.

While resecting the tumor, the normal anatomic structures of the knee can be preserved or restored in many patients.

[MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Reconstructive Surgical Procedures / methods

[MeSH-minor] Adult. Bone Transplantation. Female. Humans. Ilium / transplantation. Male. Menisci, Tibial. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Tibia. Transplantation, Autologous. Young Adult

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(PMID = 18830792.001).

[ISSN] 1528-1132

[Journal-full-title] Clinical orthopaedics and related research

[ISO-abbreviation] Clin. Orthop. Relat. Res.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2628220

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Giant cell tumour (GCT) is a benign, but aggressive, primary tumour of the bone.

In addition to curettage, various adjuvant procedures and packing materials have been advocated in order to control and reconstruct long bone defects secondary to this neoplasm.

[MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / methods. Giant Cell Tumor of Bone / surgery

[MeSH-minor] Adolescent. Adult. Aged. Child. Cohort Studies. Developing Countries. Female. Humans. Iran. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Retrospective Studies

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[Cites] Clin Orthop Relat Res. 2002 Apr;(397):259-70 [11953617.001]

[Cites] Clin Orthop Relat Res. 2002 Apr;(397):248-58 [11953616.001]

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(PMID = 16896875.001).

[ISSN] 0341-2695

[Journal-full-title] International orthopaedics

[ISO-abbreviation] Int Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

[Other-IDs] NLM/ PMC3172751

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur.

Unlike previously published examples of metastatic chondroblastoma, these metastasis developed before any operative manipulation of the primary tumor.

And primary tumor site was also unusual.

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(PMID = 20057972.001).

[ISSN] 2005-9256

[Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association

[ISO-abbreviation] Cancer Res Treat

[Language] eng

[Publication-type] Journal Article

[Publication-country] Korea (South)

[Other-IDs] NLM/ PMC2802843

[Keywords] NOTNLM ; Chondroblastoma / Lung metastasis / Spine origin

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Myositis ossificans circumscripta is a form of heterotopic ossification that is benign in nature associated to a trauma, but may appear clinically and radiologically as a malignant neoplasm.

We discuss some of the difficulties of diagnosis and histological evolution of the lesion.

KEYWORDS: Myositis ossificans; Thigh; Differential diagnosis; Nontraumatic.

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(PMID = 21629528.001).

[ISSN] 1918-3011

[Journal-full-title] Journal of clinical medicine research

[ISO-abbreviation] J Clin Med Res

[Language] eng

[Publication-type] Journal Article

[Publication-country] Canada

[Other-IDs] NLM/ PMC3104644

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Osteoid osteoma is a benign skeletal neoplasm of unknown etiology that is composed of osteoid and woven bone.

Its incidence is 11% of benign tumors and 3% of all primary bone tumors, with 6% to 13% of all cases occurring in the hand.

Osteoid osteoma of the hamate can produce ulnar-sided wrist pain in the dorsal or volar aspect of the wrist, depending on the location of the tumor in the bone.

A tumor located in the hook will produce volar pain.

[MeSH-major] Arthralgia / diagnosis. Bone Neoplasms / pathology. Hamate Bone / pathology. Osteoma, Osteoid / pathology. Ulna / pathology

[MeSH-minor] Humans. Male. Treatment Outcome. Wrist Joint / pathology. Wrist Joint / physiopathology. Wrist Joint / surgery. Young Adult

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[Copyright] Copyright 2010, SLACK Incorporated.

(PMID = 20608627.001).

[ISSN] 1938-2367

[Journal-full-title] Orthopedics

[ISO-abbreviation] Orthopedics

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Giant-cell tumor of the fourth metacarpal bone in children: case report.

Giant-cell tumor is a rare benign tumor that generally arises in long bones of the lower extremity in adults.

We highlight the rarity of this neoplasm in childhood and discuss epidemiological, clinical, radiological, and therapeutical characteristics of this pathology.

[MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / pathology. Metacarpal Bones / pathology

[MeSH-minor] Child. Humans. Male. Metacarpophalangeal Joint / physiopathology. Metacarpophalangeal Joint / surgery. Range of Motion, Articular / physiology. Reconstructive Surgical Procedures. Treatment Outcome

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[CommentIn] J Pediatr Orthop B. 2010 May;19(3):285-6 [20375665.001]

(PMID = 19898253.001).

[ISSN] 1473-5865

[Journal-full-title] Journal of pediatric orthopedics. Part B

[ISO-abbreviation] J Pediatr Orthop B

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Tumour types included 38 primary musculoskeletal malignancies, 8 metastatic tumours, 2 bony lymphomas and 2 benign lesions.

[MeSH-major] Arthroplasty, Replacement, Knee. Joint Diseases / surgery. Knee Joint / surgery. Limb Salvage. Neoplasms / surgery

[MeSH-minor] Adolescent. Adult. Aged. Amputation. Bone Neoplasms / surgery. Female. Follow-Up Studies. Humans. Intraoperative Complications. Joint Prosthesis. Male. Middle Aged. Muscle Neoplasms / surgery. Neoplasm Metastasis. Popliteal Artery / injuries. Postoperative Complications. Prosthesis Failure. Reoperation. Retrospective Studies. Surgical Wound Infection / etiology. Survival Rate. Treatment Outcome

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(PMID = 17291709.001).

[ISSN] 0748-7983

[Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

[ISO-abbreviation] Eur J Surg Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Osteitis Condensans Ilii (OCI) is a benign cause of axial low back pain.

The location of the sclerosis has been traditionally confined to the ilium and may give the false impression of sacro-iliac joint involvement.

[MeSH-major] Ilium / pathology. Ilium / physiopathology. Low Back Pain / etiology. Low Back Pain / physiopathology. Osteitis / diagnosis. Osteitis / physiopathology

[MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Diagnosis, Differential. Humans. Neoplasm Metastasis / diagnosis. Radiography. Radiology. Sacroiliac Joint / diagnostic imaging. Sacroiliac Joint / pathology. Sacroiliac Joint / physiopathology. Spondylitis, Ankylosing / diagnosis. Steroids / therapeutic use

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[Cites] Chir Organi Mov. 1989 Jul-Dec;74(3-4):101-7 [2635651.001]

[Cites] Lancet. 1975 May 17;1(7916):1135-6 [49487.001]

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[Cites] Semin Musculoskelet Radiol. 2008 Mar;12(1):72-82 [18382946.001]

(PMID = 19711079.001).

[ISSN] 1437-160X

[Journal-full-title] Rheumatology international

[ISO-abbreviation] Rheumatol. Int.

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] Germany

[Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Steroids

[Number-of-references] 24

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.

Chondromyxoid fibroma represents a rare benign cartilaginous tumor of young patients occurring in a subcortical metaphyseal location.

Based on the observed substantial morphological similarity between the cartilage canals and chondromyxoid fibroma, we suggest that the chondromyxoid fibroma represents a neoplasm originating from or mimicking the fetal cartilage canals within the immature cartilage.

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[Cites] Am J Clin Pathol. 2001 Aug;116(2):271-7 [11488075.001]

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[Cites] Am J Pathol. 2001 Sep;159(3):1009-20 [11549593.001]

(PMID = 20671262.001).

[ISSN] 1525-2191

[Journal-full-title] The American journal of pathology

[ISO-abbreviation] Am. J. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2928941

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

BACKGROUND: Chondroblastoma is a rare benign bone lesion that occurs in young patients and has a high rate of recurrence.

METHODS: We retrospectively reviewed eighty-seven cases of chondroblastoma in patients with open physes at the time of diagnosis and treatment.

[MeSH-major] Bone Neoplasms / epidemiology. Chondroblastoma / epidemiology. Femur. Neoplasm Recurrence, Local / epidemiology. Tibia

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(PMID = 19723993.001).

[ISSN] 1535-1386

[Journal-full-title] The Journal of bone and joint surgery. American volume

[ISO-abbreviation] J Bone Joint Surg Am

[Language] eng

[Publication-type] Journal Article; Multicenter Study

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Impact severity of local recurrence in giant cell tumor of bone.

We retrospectively reviewed 183 consecutive patients diagnosed with giant cell tumor at the three most common sites (distal femur, proximal tibia, and distal radius) to determine the pattern of local tumor recurrence and the impact severity of the recurrence on adjacent joint function.

The primary tumor was treated in all patients with intralesional excision of tumor by curettage.

Incomplete initial surgery, a delay in diagnosis of the recurrence of greater than 6 months, and subchondral recurrence of tumor were contributing factors in the failure to salvage the joint.

Despite its benign histology, giant cell tumor of bone is an aggressive tumor that demands meticulous attention to surgical detail and close postoperative surveillance for successful local tumor control and durable, joint-preserving function.

[MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / pathology. Neoplasm Recurrence, Local

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(PMID = 16131879.001).

[ISSN] 0009-921X

[Journal-full-title] Clinical orthopaedics and related research

[ISO-abbreviation] Clin. Orthop. Relat. Res.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

We report the case of a young adult who presented with a painful foot due to chondroblastoma associated with an aneurismal bone cyst.Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur.

Association of chondroblastoma with aneurysmal bone cyst is well documented however this association has only once been reported in the cuboid.Imaging techniques should be supplemented with an open biopsy for the final diagnosis.

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[Cites] J Bone Joint Surg Am. 1985 Jun;67(5):748-55 [3997927.001]

[Cites] Clin Orthop Relat Res. 1973 Sep;(95):300-12 [4585180.001]

[Cites] J Bone Joint Surg Br. 1970 May;52(2):205-26 [5445403.001]

[Cites] Clin Orthop Relat Res. 1996 Aug;(329):300-9 [8769465.001]

[Cites] J Bone Joint Surg Am. 2000 Aug;82-A(8):1140-5 [10954104.001]

[Cites] Tohoku J Exp Med. 2001 Aug;194(4):251-7 [11725841.001]

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[Cites] J Foot Ankle Surg. 2005 Jan-Feb;44(1):64-7 [15704086.001]

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[Cites] Foot Ankle Int. 1997 Apr;18(4):236-42 [9127115.001]

(PMID = 17999776.001).

[ISSN] 1752-1947

[Journal-full-title] Journal of medical case reports

[ISO-abbreviation] J Med Case Rep

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Other-IDs] NLM/ PMC2194702

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

PURPOSE: To compare 18F-FDG PET/CT with standard contrast-enhanced CT for the diagnosis and staging of lung neoplasms eligible for surgical resection.

Seventy-three malignant (65 non-small-cell lung carcinomas, one small-cell lung cancer, two carcinoids, and five metastases) and 11 benign lung tumors (three hamartomas, two sarcoidosis, one amyloidosis, one Wegener granulomatosis, one tuberculosis, and three areas of scarring) were finally diagnosed by histology.

Tumor staging was based on the revised American Joint Committee on Cancer.

[MeSH-major] Fluorodeoxyglucose F18. Lung Neoplasms / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed

[MeSH-minor] Contrast Media. Female. Humans. Image Enhancement. Lung Diseases / diagnosis. Male. Middle Aged. Neoplasm Staging / methods. Prospective Studies. Sensitivity and Specificity

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(PMID = 18651256.001).

[ISSN] 1600-0455

[Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)

[ISO-abbreviation] Acta Radiol

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] Sweden

[Chemical-registry-number] 0 / Contrast Media; 0Z5B2CJX4D / Fluorodeoxyglucose F18

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases.

BACKGROUND: The diagnosis of retroperitoneal lesions is one of the most difficult areas in surgical pathology.

Fine needle aspiration cytology has shown promising role in establishing the diagnosis in this region.

OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.

In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).

Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).

CONCLUSIONS: USG-guided FNAC is an inexpensive, rapid, safe, and accurate procedure for the diagnosis of retroperitoneal masses.

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[Cites] Scand J Urol Nephrol. 1974;8(3):223-6 [4428186.001]

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[Cites] Cytojournal. 2007;4:20 [17973999.001]

[Cites] Indian J Pathol Microbiol. 1992 Oct;35(4):333-9 [1344223.001]

(PMID = 21938165.001).

[ISSN] 0970-9371

[Journal-full-title] Journal of cytology

[ISO-abbreviation] J Cytol

[Language] ENG

[Publication-type] Journal Article

[Publication-country] India

[Other-IDs] NLM/ PMC3168018

[Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The role of this procedure in the management of aggressive benign or malignant hand tumors has been described only in case reports and small case series.

The other was treated with radiotherapy alone, as local tumor control would have required a hand amputation.

Functional assessment based on the Musculoskeletal Tumor Society staging system showed an average of 27.5 (range, 21-30).

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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[Cites] J Hand Surg Br. 2005 Oct;30(5):504-6 [15992973.001]

[Cites] J Pediatr Surg. 1997 May;32(5):698-702 [9165454.001]

[Cites] Arch Orthop Trauma Surg. 2008 Oct;128(10):1017-21 [17876592.001]

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[Cites] J Hand Surg Am. 1997 Jan;22(1):91-8 [9018620.001]

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(PMID = 19655212.001).

[ISSN] 1528-1132

[Journal-full-title] Clinical orthopaedics and related research

[ISO-abbreviation] Clin. Orthop. Relat. Res.

[Language] eng

[Publication-type] Comparative Study; Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC2853661

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

METHODS: Urinary NMP22 and CK18 levels of 293 patients with transitional cell carcinoma of the bladder, 400 patients with non-transitional cell carcinoma of the bladder, and 105 bladder benign disease were analysed by enzyme-linked-immunosorbent assay (ELISA).

RESULTS: The levels of urinary NMP22 and CK18 in the patients with transitional cell carcinoma of the bladder (M = 17.3 U/ml, M(CK18) = 484.2 U/L) were significantly higher than those in the non-transitional cell carcinoma of the bladder (M = 6.8 U/ml, M(CK18) = 156.0 U/L) and the benign disease group (M(NMP22) = 2.3 U/ml, M(CK18) = 66.6 U/L) (P < 0.001).

The joint sensitivity of the two markers was 91.7%.

CONCLUSION: NMP22 and CK18 are useful tumor marker for diagnosis of transitional cell carcinoma of the bladder and for monitoring the state of illness.

The joint use of the two markers can improve the sensitivity of cancer detection.

NMP22 and CK18 may become a new class of tumor markers, and to be the basis for development of a new assay with an increased efficacy for the detection and treatment of bladder cancer.

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / urine. Carcinoma, Renal Cell / urine. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local / urine. Neoplasm Staging. Prognosis. Sensitivity and Specificity. Young Adult

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(PMID = 19615282.001).

[ISSN] 0253-3766

[Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]

[ISO-abbreviation] Zhonghua Zhong Liu Za Zhi

[Language] chi

[Publication-type] English Abstract; Journal Article

[Publication-country] China

[Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-18; 0 / Nuclear Proteins; 0 / nuclear matrix protein 22

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Giant cell tumours are rare bone tumours that are characteristically benign but locally aggressive, most frequently occurring in the distal femur with pathological fractures being common.

[MeSH-major] Femoral Fractures / epidemiology. Femoral Fractures / physiopathology. Femoral Neoplasms / physiopathology. Giant Cell Tumor of Bone / physiopathology

[MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Female. Humans. Incidence. Male. Middle Aged. Neoplasm Recurrence, Local. Prospective Studies. Risk Factors

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[Cites] Clin Orthop Relat Res. 2002 Apr;(397):248-58 [11953616.001]

[Cites] J Bone Joint Surg Br. 2004 Jan;86(1):5-12 [14765857.001]

[Cites] J Bone Joint Surg Am. 1970 Jun;52(4):619-64 [5479455.001]

[Cites] J Bone Joint Surg Am. 1975 Mar;57(2):167-73 [1112843.001]

[Cites] J Bone Joint Surg Am. 1976 Dec;58(8):1047-55 [1002744.001]

[Cites] J Bone Joint Surg Am. 1982 Jun;64(5):755-61 [7045129.001]

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[Cites] Chir Organi Mov. 1990;75(1 Suppl):241-3 [2249540.001]

[Cites] J Bone Joint Surg Am. 1986 Feb;68(2):235-42 [3511063.001]

(PMID = 16474936.001).

[ISSN] 0341-2695

[Journal-full-title] International orthopaedics

[ISO-abbreviation] Int Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

[Other-IDs] NLM/ PMC2532068

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Fifteen years of bone tumor cryosurgery: a single-center experience of 440 procedures and long-term follow-up.

BACKGROUND: This summary of a single center's extensive cumulative experience in bone tumor cryosurgery assesses the long-term outcome of bone conservation surgery in which adjuvant cryosurgery plays a pivotal role.

Two-thirds of the series comprised a variety of primary benign-aggressive and low-grade malignant lesions, and one-third were primary high-grade and metastatic bone tumors.

There were three cases of transient nerve palsies in areas other than the sacrum, and four cases of late osteoarthritis of an adjacent joint.

The functional outcome for the 372 patients with no evidence of disease was almost 100% "good" and "excellent" (American Musculo-skeletal Tumor Society System).

CONCLUSIONS: Bone cryosurgery is a safe and effective limb-, joint- and even epiphysis-sparing surgical technique in suitable types of bone tumors, temporarily or permanently obviating the need for resection surgery.

[MeSH-major] Bone Neoplasms / surgery. Cryosurgery. Neoplasm Recurrence, Local

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(PMID = 18158228.001).

[ISSN] 1532-2157

[Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

[ISO-abbreviation] Eur J Surg Oncol

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Malignant and benign tumors were managed in 25 (80.6%) and six (19.4%) cases, respectively.

American Joint Committee on Cancer tumor staging was T3N0M0 and T4N0M0 in 14 (56%) and 11 (44%) of the malignant cases, respectively.

CONCLUSIONS: This study validated technical feasibility of MIER for diversity of benign and malignant ASB histopathology.

[MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / surgery. Carcinoma, Squamous Cell / surgery. Esthesioneuroblastoma, Olfactory / surgery. Feasibility Studies. Female. Follow-Up Studies. Humans. Male. Melanoma / surgery. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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(PMID = 19877265.001).

[ISSN] 1531-4995

[Journal-full-title] The Laryngoscope

[ISO-abbreviation] Laryngoscope

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

When there is a recurrence of GCT, with or without metastases, the local and possibly the metastases should be biopsied to confirm the original diagnosis.

Progression of benign GCT into an aggressive sarcoma has been documented, and the method of management should be altered.

[MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology

[MeSH-minor] Adolescent. Adult. Biopsy, Needle. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Prognosis. Retrospective Studies. Risk Assessment. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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[Cites] Clin Orthop Relat Res. 2002 Aug;(401):202-8 [12151897.001]

[Cites] Int Orthop. 2006 Dec;30(6):499-504 [16909252.001]

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(PMID = 18461324.001).

[ISSN] 1432-5195

[Journal-full-title] International orthopaedics

[ISO-abbreviation] Int Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] Germany

[Other-IDs] NLM/ PMC2899057

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Giant cell tumor of the uterus: case report and response to chemotherapy.

BACKGROUND: Giant cell tumor (GCT) is usually a benign but locally aggressive primary bone neoplasm in which monocytic macrophage/osteoclast precursor cells and multinucleated osteoclast-like giant cells infiltrate the tumor.

The etiology of GCT is unknown, however the tumor cells of GCT have been reported to produce chemoattractants that can attract osteoclasts and osteoclast precursors.

[MeSH-minor] Angiogenesis Inhibitors / administration & dosage. Antibiotics, Antineoplastic / administration & dosage. Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Humanized. Antineoplastic Agents, Alkylating / administration & dosage. Bevacizumab. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Humans. Hysterectomy. Ifosfamide / administration & dosage. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Middle Aged. Treatment Outcome

MedlinePlus Health Information. consumer health - Uterine Cancer.

COS Scholar Universe. author profiles.

Hazardous Substances Data Bank. DOXORUBICIN .

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(PMID = 17359524.001).

[ISSN] 1471-2407

[Journal-full-title] BMC cancer

[ISO-abbreviation] BMC Cancer

[Language] eng

[Publication-type] Case Reports; Journal Article; Review

[Publication-country] England

[Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibiotics, Antineoplastic; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents, Alkylating; 2S9ZZM9Q9V / Bevacizumab; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide

[Number-of-references] 57

[Other-IDs] NLM/ PMC1832205

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Some rare extraparotid lesions, originating from the temporomandibular joint and the mandible itself, also share the same localization and therefore are to be taken into consideration for the differential diagnosis with parotid lesions.

Central GCG (CGCG) is an uncommon benign fibro-osseous lesion generally presenting as an expansible mass with cortical bone defect.

The brown tumor of hyperparathyroidism and giant cell tumor must be ruled out because of the microscopic similarities of these lesions.

The first case of PGCG of the mandible condyle is presented, and attention is drawn to mandibular diseases for the differential diagnosis of the preauricular mass.

[MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Tomography, X-Ray Computed

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[ISSN] 0937-4477

[Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

[ISO-abbreviation] Eur Arch Otorhinolaryngol

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

METHODS: 20 patients with histologically benign GCT of the pelvis were included in this study.

RESULTS: 1 patient with a pubic tumor developed a local recurrence 1 year after intralesional resection and additional curettage of the margins.

[MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Pelvic Bones

[MeSH-minor] Adult. Aged. Bone Cements. Bone Transplantation. Curettage. Embolization, Therapeutic / methods. Female. Follow-Up Studies. Humans. Ilium / pathology. Ilium / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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(PMID = 19916695.001).

[ISSN] 1745-3682

[Journal-full-title] Acta orthopaedica

[ISO-abbreviation] Acta Orthop

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

[Chemical-registry-number] 0 / Bone Cements

[Other-IDs] NLM/ PMC2823344