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1. Cao Y, Paner GP, Perry KT, Flanigan RC, Campbell SC, Picken MM: Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System. Arch Pathol Lab Med; 2005 Apr;129(4):487-91
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  • [Title] Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System.
  • Recent modification of the World Health Organization histologic classification and the American Joint Committee on Cancer staging system of adult renal tumors further highlighted the need for case analysis in this age group.
  • The tumors were reevaluated according to the 2004 World Health Organization classification and the 2002 American Joint Committee on Cancer staging system.
  • Seventeen percent of these tumors had multilocular cystic features involving more than 50% of the tumor volume (55%-85%).
  • The number of oncocytomas was also significantly lower in younger adults than in older adults (2% vs 11%, P < .001), and this presumably age-related benign neoplasm was not identified in patients younger than 40 years in this study.
  • In contrast, the miscellaneous tumor category showed a remarkable increase, from 4% in older adults to 26% in younger adults (P < .001).
  • Younger female adults tended to have more benign miscellaneous neoplasms than did their male counterparts (64% vs 36%, P < .001).
  • Malignant and benign renal neoplasms tend to have a contrasting sex distribution in younger adults.
  • [MeSH-minor] Adult. Age Distribution. Female. Humans. Male. Neoplasm Staging. Sex Distribution

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  • (PMID = 15794671.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. Unglaub F, Loos B, Wolf MB, Dragu A, Amann K, Horch RE: Malignant Natural-Killer cell neoplasm presenting as a mucous cyst on the distal interphalangeal joint of the finger. Arch Orthop Trauma Surg; 2009 Dec;129(12):1613-6
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  • [Title] Malignant Natural-Killer cell neoplasm presenting as a mucous cyst on the distal interphalangeal joint of the finger.
  • The analysis revealed the presence of a Natural-Killer cell neoplasm.
  • This case illustrates and stresses the importance of a pathohistological examination when doubts arise about the initial diagnosis of a benign tumorous lesion.
  • [MeSH-minor] Aged. Cysts / diagnosis. Fingers. Humans. Male

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  • (PMID = 19084980.001).
  • [ISSN] 1434-3916
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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3. Maceroli M, Uglialoro AD, Beebe KS, Benevenia J: Recurrent knee pain in an athletic adult: multiple schwannomas secondary to schwannomatosis: a case report. Am J Orthop (Belle Mead NJ); 2010 Nov;39(11):E119-22
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  • In our case, a 28-year-old athletic man underwent a right knee excisional biopsy for multifocal, benign schwannomatosis.
  • Excisional biopsy of discrete masses was performed and histologic examination revealed recurrent benign schwannomatosis.
  • To our knowledge, this is the second reported case of recurrent benign schwannomatosis.
  • [MeSH-major] Athletes. Neoplasm Recurrence, Local. Neurilemmoma / diagnosis. Neurofibromatoses / diagnosis. Pain / diagnosis. Peripheral Nervous System Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Humans. Ilium / pathology. Ilium / surgery. Knee Joint / pathology. Knee Joint / physiopathology. Knee Joint / surgery. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 21623424.001).
  • [ISSN] 1934-3418
  • [Journal-full-title] American journal of orthopedics (Belle Mead, N.J.)
  • [ISO-abbreviation] Am J. Orthop.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; Schwannomatosis
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4. Bahamonde L, Catalan J: Bone tumors around the knee: risks and benefits of arthroscopic procedures. Arthroscopy; 2006 May;22(5):558-64
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  • Although most primary bone tumors and soft tissue tumors arise around the knee joint, many patients with tumoral conditions attribute their symptoms to traumatic events.
  • Arthroscopy is the preferred method for diagnosis and treatment of knee joint disease, but even a minimally invasive procedure may have adverse consequences in the presence of an unsuspected neoplasm.
  • In addition, arthroscopy is a useful adjunct during surgical treatment of patients with certain juxta-articular benign bone tumors.
  • In this Current Concepts review, we consider the risks and benefits of arthroscopy in the presence of tumors about the knee joint.
  • [MeSH-major] Arthroscopy. Bone Neoplasms / surgery. Knee Joint
  • [MeSH-minor] Biopsy. Humans. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery

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  • (PMID = 16651168.001).
  • [ISSN] 1526-3231
  • [Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • [ISO-abbreviation] Arthroscopy
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
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5. Boriani S, Bandiera S, Donthineni R, Amendola L, Cappuccio M, De Iure F, Gasbarrini A: Morbidity of en bloc resections in the spine. Eur Spine J; 2010 Feb;19(2):231-41
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  • The study was set up to correlate diagnosis, staging and treatment with the outcome.
  • Oncological and functional results were recorded for all patients at periodic, diagnosis-related controls, until death or the latest follow-up examination (from 0 to 211 months, median 47 months, 25th-75th percentile 22-85 months).
  • Of the 35 patients with a recurrent or contaminated tumor, 16 (45.7%) suffered at least one complication; by contrast, complications arose in 31 (31.3%) of the 99 patients who had had no previous treatment and who underwent the whole of their treatment in the same center (P = 0.125).
  • Re-operations were mostly due to tumor recurrences, but also to hardware failures, wound dehiscence, hematomas and aortic dissection.
  • En bloc resection is able to improve the prognosis of aggressive benign and low-grade malignant tumors in the spine; however, complications are not rare and possibly fatal.
  • [MeSH-minor] Adult. Aged. Aortic Rupture / mortality. Equipment Failure. Female. Humans. Male. Middle Aged. Mortality. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Outcome Assessment (Health Care). Radiotherapy / adverse effects. Reoperation / mortality. Retrospective Studies. Surgical Wound Dehiscence / mortality. Surgical Wound Infection / mortality. Treatment Outcome

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  • (PMID = 19690899.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
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6. Singh S, Singh R, Singh UP, Rai SN, Novakovic KR, Chung LW, Didier PJ, Grizzle WE, Lillard JW Jr: Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines. Int J Cancer; 2009 Nov 15;125(10):2288-95
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  • While prostate tumor tissues with Gleason scores >or= 7, displayed predominantly nuclear CXCR5 expression patterns, PCa specimens with Gleason scores <or= 6 showed predominantly membrane and cytoplasmic expression patterns that were comparable to benign prostatic hyperplasia (BPH).

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  • (PMID = 19610059.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U54 CA118638; United States / NCRR NIH HHS / RR / G12 RR003034; United States / NCI NIH HHS / CA / U54 CA118623; United States / NCI NIH HHS / CA / U54 CA118948; United States / NIMHD NIH HHS / MD / P60 MD000525-03; United States / NIMHD NIH HHS / MD / MD00525; United States / NIMHD NIH HHS / MD / P60 MD000525; United States / NIAID NIH HHS / AI / AI057808; United States / NCI NIH HHS / CA / U54 CA118638-06; United States / NIGMS NIH HHS / GM / S06 GM008248; United States / NIGMS NIH HHS / GM / GM09248; United States / NIAID NIH HHS / AI / R01 AI057808; United States / NIDDK NIH HHS / DK / DK58967; United States / NIAID NIH HHS / AI / AI057808-05; United States / NCI NIH HHS / CA / U54 CA118638-07; United States / NCI NIH HHS / CA / U24 CA086359; United States / NIGMS NIH HHS / GM / GM08248; United States / NCI NIH HHS / CA / U56 CA092078; United States / NIAID NIH HHS / AI / R01 AI057808-05; United States / NCI NIH HHS / CA / CA086359; United States / NCI NIH HHS / CA / CA092078
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CXCL13 protein, human; 0 / CXCR5 protein, human; 0 / Chemokine CXCL13; 0 / RNA, Messenger; 0 / Receptors, CXCR5; EC 3.4.24.- / Matrix Metalloproteinases
  • [Other-IDs] NLM/ NIHMS137666; NLM/ PMC3600527
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7. Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Jr: Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett; 2009 Sep 28;283(1):29-35
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  • In this study, we present the first evidence that CXCL13, the only ligand for CXCR5, and IL-6 were significantly elevated in PCa patient serum compared to serum from subjects with benign prostatic hyperplasia (BPH), or high-grade prostatic intraepithelial neoplasia (HGPIN) as well as normal healthy donors (NHD).

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  • (PMID = 19375853.001).
  • [ISSN] 1872-7980
  • [Journal-full-title] Cancer letters
  • [ISO-abbreviation] Cancer Lett.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / G12 RR003034-27; United States / NCRR NIH HHS / RR / G12 RR003034-23; United States / NCRR NIH HHS / RR / G12 RR003034; United States / NCI NIH HHS / CA / U24 CA086359-10; United States / NIMHD NIH HHS / MD / P60 MD000525-03; United States / NIMHD NIH HHS / MD / MD00525; United States / NIMHD NIH HHS / MD / P60 MD000525; United States / NIAID NIH HHS / AI / AI057808; United States / NCRR NIH HHS / RR / RR003034-23; United States / NIGMS NIH HHS / GM / S06 GM008248; United States / NIGMS NIH HHS / GM / GM09248; United States / NCRR NIH HHS / RR / RR03034; United States / NIGMS NIH HHS / GM / GM008248-22; United States / NIAID NIH HHS / AI / R01 AI057808; United States / NIDDK NIH HHS / DK / DK58967; United States / NCI NIH HHS / CA / U24CA86359.; United States / NCI NIH HHS / CA / U24 CA086359; United States / NIGMS NIH HHS / GM / GM08248; United States / NIGMS NIH HHS / GM / S06 GM008248-22; United States / NCI NIH HHS / CA / U56 CA092078; United States / NCI NIH HHS / CA / CA086359-10; United States / NCI NIH HHS / CA / CA092078
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CXCL13 protein, human; 0 / CXCR5 protein, human; 0 / Chemokine CXCL13; 0 / Integrins; 0 / Interleukin-6; 0 / Receptors, CXCR5; EC 3.4.21.77 / Prostate-Specific Antigen
  • [Other-IDs] NLM/ NIHMS140687; NLM/ PMC3600557
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8. Eversole R, Su L, ElMofty S: Benign fibro-osseous lesions of the craniofacial complex. A review. Head Neck Pathol; 2008 Sep;2(3):177-202
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  • [Title] Benign fibro-osseous lesions of the craniofacial complex. A review.
  • Benign fibro-osseous lesions of the craniofacial complex are represented by a variety of disease processes that are characterized by pathologic ossifications and calcifications in association with a hypercellular fibroblastic marrow element.
  • The definitive diagnosis can rarely be rendered on the basis of histopathologic features alone; rather, procurement of a final diagnosis is usually dependent upon assessment of microscopic, clinical and imaging features together.
  • [MeSH-major] Cementoma / diagnosis. Fibroma, Ossifying / diagnosis. Fibrous Dysplasia of Bone / diagnosis. Osteitis Deformans / diagnosis. Skull Neoplasms / diagnosis
  • [MeSH-minor] DNA, Neoplasm / analysis. Humans. Mutation

  • MedlinePlus Health Information. consumer health - Paget's Disease of Bone.
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  • (PMID = 20614314.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ PMC2807558
  • [Keywords] NOTNLM ; Benign fibroosseous lesions / Cementoma / Cementoosseous dysplasia / Fibrous dysplasia / Ossifying fibroma / Osteitis deformans
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9. Kalish LH, Ng T, Kalnins I, Da Cruz MJ: Pseudogout mimicking an infratemporal fossa tumor. Head Neck; 2010 Jan;32(1):127-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pseudogout mimicking an infratemporal fossa tumor.
  • METHODS AND RESULTS: We present a case of a 71-year-old woman who presented with worsening facial pain, trismus, and a large mass in her infratemporal fossa with minimal associated temporomandibular joint destruction.
  • CONCLUSION: The clinical and radiological features of patients with tophaceous pseudogout frequently mimic those of a benign or malignant neoplasm of the infratemporal fossa, often resulting in more radical surgery.
  • [MeSH-major] Chondrocalcinosis / diagnosis. Chondrocalcinosis / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery. Temporal Bone / surgery
  • [MeSH-minor] Aged. Diagnosis, Differential. Facial Pain / etiology. Female. Humans. Otorhinolaryngologic Surgical Procedures / methods. Temporomandibular Joint / pathology. Treatment Outcome. Trismus / etiology

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  • (PMID = 19283846.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Carlson JA, Ross JS, Slominski AJ: New techniques in dermatopathology that help to diagnose and prognosticate melanoma. Clin Dermatol; 2009 Jan-Feb;27(1):75-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Routine light microscopy supplemented with immunohistochemistry in cases of metastatic or spindle cell melanoma are standards of care for the diagnosis and staging of melanoma.
  • Not all melanocytic tumors can be confidently classified as melanoma or benign nevus by histology, however.
  • In addition, tumor thickness and ulceration, the current American Joint Classification on Cancer prognosticators for primary cutaneous (stages I and II) melanoma used in clinical practice, do not perfectly predict an individual's clinical course.
  • Recent advances in molecular techniques and bioinformatics mandate testing and use of novel methods for the detection, diagnosis, and classification of melanocytic tumors that can accurately predict tumor behavior and help in selecting the most optimal and individualized therapy.
  • [MeSH-minor] Cytogenetic Analysis. Dermatology / methods. Humans. Immunohistochemistry. Molecular Diagnostic Techniques. Neoplasm Staging. Prognosis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
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  • (PMID = 19095155.001).
  • [ISSN] 1879-1131
  • [Journal-full-title] Clinics in dermatology
  • [ISO-abbreviation] Clin. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 288
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11. Suresh S, Saifuddin A: Unveiling the 'unique bone': a study of the distribution of focal clavicular lesions. Skeletal Radiol; 2008 Aug;37(8):749-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There is no study discussing the differential diagnosis of clavicular lesions based on the site of occurrence or age at presentation.
  • This study aims to determine whether the distribution of lesions affecting the clavicle and age at presentation aid in the differential diagnosis of focal clavicular lesions.
  • Virtually, all patients had been referred as suspected neoplasm.
  • Patients <20 years (n = 27) had non-neoplastic or benign lesions.
  • The lesions most commonly affected the medial third (n = 35) and were predominantly non-neoplastic or benign.
  • The middle third was affected in 15 patients and showed both benign and malignant lesions.
  • CONCLUSIONS: The clavicle is not a primary common site for any particular tumour; hence, diagnosis of the lesions can be challenging.
  • Our study has suggested that few factors like age and site of the lesions may be helpful in diagnosis.
  • [MeSH-major] Bone Diseases / diagnosis. Clavicle / pathology
  • [MeSH-minor] Adult. Biopsy. Bone Neoplasms / diagnosis. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Osteomyelitis / diagnosis. Tomography, X-Ray Computed / methods

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  • (PMID = 18483738.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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12. Lee JW, Kim BS, Lee DS, Chung JK, Lee MC, Kim S, Kang WJ: 18F-FDG PET/CT in mediastinal lymph node staging of non-small-cell lung cancer in a tuberculosis-endemic country: consideration of lymph node calcification and distribution pattern to improve specificity. Eur J Nucl Med Mol Imaging; 2009 Nov;36(11):1794-802
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  • Mediastinal node staging was determined using the American Joint Committee on Cancer (AJCC) staging system.
  • After lymph nodes with calcification and bilateral hilar distribution were considered benign, sensitivity and specificity of PET/CT were 75% and 89% on a per-patient basis and 66% and 96% on a per-node station basis.
  • [MeSH-minor] Contrast Media. Endemic Diseases. False Positive Reactions. Female. Humans. Male. Middle Aged. Neoplasm Staging. Positron-Emission Tomography. Radiography, Thoracic. Sensitivity and Specificity. Tomography, X-Ray Computed


13. Mackenzie H, Gulati V, Tross S: A rare case of a swollen knee due to disseminated synovial chondromatosis: a case report. J Med Case Rep; 2010;4:113
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  • INTRODUCTION: A synovial chondromatosis is a rare benign neoplasm on the synovium.
  • Although described as a benign disease, it can be very destructive and can cause severe osteoarthritis and pain.
  • To the best of our knowledge, we report the first known case of an extensive presentation of this intra-articular and extra-articular disease of the knee joint.
  • CONCLUSIONS: Although synovial chondromatosis is described as a benign disease, it can be very destructive and debilitating.

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  • (PMID = 20416049.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2873448
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14. Mentzel T, Toennissen J, Rütten A, Schaller J: Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location. Virchows Arch; 2005 Mar;446(3):300-4
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  • [Title] Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location.
  • Lipomatous tumours, both benign and malignant, arising on the hands are uncommon.
  • The neoplasm presented as a long-standing, exophytic neoplasm measuring 9 x 9 cm.
  • The well-circumscribed neoplasm was completely excised, and margins were tumour free.
  • Histologically, the neoplasm showed features closely resembling spindle cell lipoma, being composed of mature adipocytic cells associated with bland, neuroid spindle cells staining positively for CD34.
  • Aypical lipomatous tumour with spindle cell features may arise very rarely in palmar location and has to be distinguished from a number of benign and malignant mesenchymal neoplasms.
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 15719245.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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15. Zhang Q, Zhao H, Maheshwari AV, Cai L, Yu F, Niu X: Isolated cardiac metastasis from a histologically "benign" giant-cell tumor of the distal end of the femur: a case report. J Bone Joint Surg Am; 2010 Nov 17;92(16):2725-31
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  • [Title] Isolated cardiac metastasis from a histologically "benign" giant-cell tumor of the distal end of the femur: a case report.
  • [MeSH-major] Bone Neoplasms / pathology. Femur / pathology. Giant Cell Tumor of Bone / secondary. Heart Neoplasms / secondary
  • [MeSH-minor] Adult. Biopsy, Needle. Disease Progression. Fatal Outcome. Heart Failure / diagnosis. Humans. Immunohistochemistry. Male. Neoplasm Staging. Orthopedic Procedures / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 21084583.001).
  • [ISSN] 1535-1386
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Kim J, Takeuchi H, Lam ST, Turner RR, Wang HJ, Kuo C, Foshag L, Bilchik AJ, Hoon DS: Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival. J Clin Oncol; 2005 Apr 20;23(12):2744-53
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  • METHODS: CRC cell lines (n = 6) and tumor specimens (n = 139) from patients with different American Joint Committee on Cancer (AJCC) stages of CRC were assessed.
  • CXCR4 expression in tumor and benign specimens was assessed by quantitative real-time reverse transcription polymerase chain reaction and correlated with disease recurrence and overall survival.
  • RESULTS: High CXCR4 expression in tumor specimens (n = 57) from AJCC stage I/II patients was associated with increased risk for local recurrence and/or distant metastasis (risk ratio, 1.35; 95% CI, 1.09 to 1.68; P = .0065).
  • High CXCR4 expression in primary tumor specimens (n = 35) from AJCC stage IV patients correlated with worse overall median survival (9 months v 23 months; RR, 2.53; 95% CI, 1.19 to 5.40; P = .016).
  • [MeSH-major] Colorectal Neoplasms / genetics. Colorectal Neoplasms / pathology. Gene Expression Profiling. Liver Neoplasms / genetics. Liver Neoplasms / secondary. Neoplasm Recurrence, Local / genetics. Receptors, CXCR4 / biosynthesis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Metastasis / physiopathology. Prognosis. Risk Factors. Signal Transduction. Survival Analysis. Tumor Cells, Cultured

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  • (PMID = 15837989.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01-CA90848-02
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, CXCR4
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17. Aneiros-Fernandez J, Caba-Molina M, Arias-Santiago S, Ovalle F, Hernandez-Cortes P, Aneiros-Cachaza J: Myositis ossificans circumscripta without history of trauma. J Clin Med Res; 2010 May 19;2(3):142-4
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  • Myositis ossificans circumscripta is a form of heterotopic ossification that is benign in nature associated to a trauma, but may appear clinically and radiologically as a malignant neoplasm.
  • We discuss some of the difficulties of diagnosis and histological evolution of the lesion.
  • KEYWORDS: Myositis ossificans; Thigh; Differential diagnosis; Nontraumatic.

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  • (PMID = 21629528.001).
  • [ISSN] 1918-3011
  • [Journal-full-title] Journal of clinical medicine research
  • [ISO-abbreviation] J Clin Med Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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18. Abdel MP, Papagelopoulos PJ, Morrey ME, Wenger DE, Rose PS, Sim FH: Surgical management of 121 benign proximal fibula tumors. Clin Orthop Relat Res; 2010 Nov;468(11):3056-62
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  • [Title] Surgical management of 121 benign proximal fibula tumors.
  • Patients with aggressive benign tumors in the proximal fibula may require en bloc resection.
  • QUESTIONS/PURPOSES: We therefore analyzed the incidence of peroneal nerve palsy, knee stability, and local recurrence following surgical treatment of benign proximal fibula tumors.
  • METHODS: We retrospectively reviewed the charts of 120 patients (121 tumors) with histologically confirmed aggressive benign tumors of the proximal fibula.
  • The most common diagnosis was osteochondroma (38%) followed by giant cell tumor (19%).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Curettage / adverse effects. Female. Humans. Joint Instability / etiology. Joint Instability / physiopathology. Knee Joint / physiopathology. Male. Middle Aged. Neoplasm Recurrence, Local. Osteotomy / adverse effects. Peroneal Neuropathies / etiology. Range of Motion, Articular. Retrospective Studies. Surgical Wound Dehiscence / etiology. Time Factors. Treatment Outcome. Venous Thrombosis / etiology. Young Adult

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  • (PMID = 20625947.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2947668
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19. Quaia E, Tona G, Gelain F, Lubin E, Pizzolato R, Boscolo E, Bussoli L: Integrated fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT compared to standard contrast-enhanced CT for characterization and staging of pulmonary tumors eligible for surgical resection. Acta Radiol; 2008 Nov;49(9):995-1004
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  • PURPOSE: To compare 18F-FDG PET/CT with standard contrast-enhanced CT for the diagnosis and staging of lung neoplasms eligible for surgical resection.
  • Seventy-three malignant (65 non-small-cell lung carcinomas, one small-cell lung cancer, two carcinoids, and five metastases) and 11 benign lung tumors (three hamartomas, two sarcoidosis, one amyloidosis, one Wegener granulomatosis, one tuberculosis, and three areas of scarring) were finally diagnosed by histology.
  • Tumor staging was based on the revised American Joint Committee on Cancer.
  • [MeSH-major] Fluorodeoxyglucose F18. Lung Neoplasms / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Contrast Media. Female. Humans. Image Enhancement. Lung Diseases / diagnosis. Male. Middle Aged. Neoplasm Staging / methods. Prospective Studies. Sensitivity and Specificity

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  • (PMID = 18651256.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Contrast Media; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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20. Milot L, Guindi M, Gallinger S, Moulton CA, Brock KK, Dawson LA, Haider MA: MR imaging correlates of intratumoral tissue types within colorectal liver metastases: a high-spatial-resolution fresh ex vivo radiologic-pathologic correlation study. Radiology; 2010 Mar;254(3):747-54
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  • This SI pattern is unusual for common benign liver lesions and may be helpful in the MR imaging diagnosis of colorectal liver metastases. (c) RSNA, 2010.
  • [MeSH-major] Colorectal Neoplasms / pathology. Liver Neoplasms / diagnosis. Liver Neoplasms / secondary. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. In Vitro Techniques. Linear Models. Male. Middle Aged. Neoplasm Staging. Prospective Studies


21. He H, Chen G, Zhou L, Liu Y: A joint detection of CEA and CA-50 levels in saliva and serum of patients with tumors in oral region and salivary gland. J Cancer Res Clin Oncol; 2009 Oct;135(10):1315-21
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  • [Title] A joint detection of CEA and CA-50 levels in saliva and serum of patients with tumors in oral region and salivary gland.
  • METHODS: The concentrations of salivary CEA and CA-50 were assayed in 80 patients of oral and salivary malignant tumors, 40 patients of benign tumors and 80 health controls.
  • RESULTS: Salivary CEA and CA-50 levels were significantly higher in malignant tumors than in benign tumors and in health controls, respectively (P < 0.001).
  • This may be more useful as prognostic indicators in early diagnosis of oral and salivary malignant tumors.
  • [MeSH-major] Adenoma / blood. Antigens, Tumor-Associated, Carbohydrate / analysis. Carcinoembryonic Antigen / analysis. Mouth Neoplasms / blood. Saliva / chemistry. Salivary Gland Neoplasms / blood
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. Enzyme-Linked Immunosorbent Assay. Female. Humans. Immunoradiometric Assay. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate. Young Adult

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  • (PMID = 19322585.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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22. Gaeta M, Mazziotti S, Minutoli F, Genitori A, Toscano A, Rodolico C, Blandino A: MR imaging findings of focal myositis: a pseudotumour that may mimic muscle neoplasm. Skeletal Radiol; 2009 Jun;38(6):571-8
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  • [Title] MR imaging findings of focal myositis: a pseudotumour that may mimic muscle neoplasm.
  • Dynamic enhancement pattern corresponded to the type usually seen in benign soft tissue lesions.
  • CONCLUSION: Focal myositis is an uncommon pseudotumour which should be considered in the differential diagnosis of muscular masses and myopathies.
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19255757.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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23. do Egito Vasconcelos BC, Porto GG, Bessa-Nogueira RV: Rare benign tumors of the mandibular condyle: report of 2 cases and literature review. J Oral Maxillofac Surg; 2007 Sep;65(9):1830-5
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  • [Title] Rare benign tumors of the mandibular condyle: report of 2 cases and literature review.
  • [MeSH-minor] Adult. Diagnosis, Differential. Dislocations / etiology. Dislocations / surgery. Facial Asymmetry / etiology. Facial Asymmetry / surgery. Female. Humans. Neoplasm Invasiveness. Rare Diseases. Temporomandibular Joint Disc / surgery. Temporomandibular Joint Disorders / etiology. Temporomandibular Joint Disorders / surgery

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  • (PMID = 17719407.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
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24. Miller IJ, Blank A, Yin SM, McNickle A, Gray R, Gitelis S: A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases. Diagn Pathol; 2010;5:62
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  • [Title] A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases.
  • Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis.
  • Vascular invasion outside the boundary of the tumor can be seen.
  • Metastasis, with identical morphology to the primary tumor, occurs in a few percent of cases, usually to the lung.
  • [MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local. Tibia / pathology

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  • (PMID = 20860830.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bone Cements
  • [Other-IDs] NLM/ PMC2954972
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25. Rubin G, Wolovelsky A, Rinott M, Rozen N: Osteoid osteoma of the hamate: an unusual cause of ulnar-sided wrist pain. Orthopedics; 2010 Jul;33(7):513
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  • Osteoid osteoma is a benign skeletal neoplasm of unknown etiology that is composed of osteoid and woven bone.
  • Its incidence is 11% of benign tumors and 3% of all primary bone tumors, with 6% to 13% of all cases occurring in the hand.
  • Osteoid osteoma of the hamate can produce ulnar-sided wrist pain in the dorsal or volar aspect of the wrist, depending on the location of the tumor in the bone.
  • A tumor located in the hook will produce volar pain.
  • [MeSH-major] Arthralgia / diagnosis. Bone Neoplasms / pathology. Hamate Bone / pathology. Osteoma, Osteoid / pathology. Ulna / pathology
  • [MeSH-minor] Humans. Male. Treatment Outcome. Wrist Joint / pathology. Wrist Joint / physiopathology. Wrist Joint / surgery. Young Adult

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20608627.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Mohler DG, Chiu R, McCall DA, Avedian RS: Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function. Clin Orthop Relat Res; 2010 Oct;468(10):2765-73
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  • Grade 1 chondrosarcomas have little or no metastatic potential and are often difficult to distinguish from painful benign enchondromas.
  • Patients were followed a minimum of 18 months (average, 47.2. months; range, 18-134 months) for evidence of recurrence and for assessment of Musculoskeletal Tumor Society (MSTS) functional score.
  • RESULTS: Two of the 46 patients had recurrences in the original tumor site (4.3% recurrence rate), which subsequently were removed by wide excision, and both patients were confirmed to be disease-free 36 and 30 months, respectively, after the second surgery.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Recovery of Function. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 20574801.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3049634
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27. Micheli A, Trapani S, Brizzi I, Campanacci D, Resti M, de Martino M: Myositis ossificans circumscripta: a paediatric case and review of the literature. Eur J Pediatr; 2009 May;168(5):523-9
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  • At onset, it is difficult to distinguish MOC from a musculoskeletal infection or neoplasm, particularly in absence of trauma, and a biopsy is frequently required.
  • Three months after diagnosis, surgical excision was performed.
  • Our case study confirms the good prognosis of MOC and underlines how this benign condition should be considered in children presenting a tender and painful soft-tissue swelling.
  • [MeSH-major] Bone and Bones. Musculoskeletal Diseases. Myositis Ossificans / diagnosis. Myositis Ossificans / physiopathology
  • [MeSH-minor] Anti-Bacterial Agents / therapeutic use. Anti-Inflammatory Agents / therapeutic use. Biopsy. Child. Diagnosis, Differential. Humans. Lymphadenitis / diagnosis. Magnetic Resonance Imaging. Male. Muscle, Skeletal / metabolism. Muscle, Skeletal / pathology. Necrosis / pathology. Osteoblasts / metabolism. Sarcoma / pathology. Soft Tissue Injuries / diagnosis. Soft Tissue Injuries / metabolism. Soft Tissue Injuries / pathology

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  • (PMID = 19130083.001).
  • [ISSN] 1432-1076
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Anti-Inflammatory Agents
  • [Number-of-references] 35
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28. Sailhan F, Chotel F, Parot R, SOFOP: Chondroblastoma of bone in a pediatric population. J Bone Joint Surg Am; 2009 Sep;91(9):2159-68
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  • BACKGROUND: Chondroblastoma is a rare benign bone lesion that occurs in young patients and has a high rate of recurrence.
  • METHODS: We retrospectively reviewed eighty-seven cases of chondroblastoma in patients with open physes at the time of diagnosis and treatment.
  • [MeSH-major] Bone Neoplasms / epidemiology. Chondroblastoma / epidemiology. Femur. Neoplasm Recurrence, Local / epidemiology. Tibia

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  • (PMID = 19723993.001).
  • [ISSN] 1535-1386
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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29. Jones KB, DeYoung BR, Morcuende JA, Buckwalter JA: Ethanol as a local adjuvant for giant cell tumor of bone. Iowa Orthop J; 2006;26:69-76
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  • [Title] Ethanol as a local adjuvant for giant cell tumor of bone.
  • Giant cell tumor is an aggressive benign neoplasm of bone.
  • No report on its use in a group of patients with giant cell tumor is available.
  • [MeSH-major] Bone Neoplasms / therapy. Ethanol / therapeutic use. Giant Cell Tumor of Bone / therapy

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  • (PMID = 16789453.001).
  • [ISSN] 1541-5457
  • [Journal-full-title] The Iowa orthopaedic journal
  • [ISO-abbreviation] Iowa Orthop J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 3K9958V90M / Ethanol
  • [Other-IDs] NLM/ PMC1888590
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30. Sailon AM, Cappuccino G, Hameed M, Fleegler EJ: Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report. Eplasty; 2008;8:e38
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  • [Title] Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report.
  • OBJECTIVE: This study describes a case of nodular fasciitis involving the hand and reviews the neoplasm's pertinent clinical, histologic, and pathologic features.
  • CONCLUSIONS: Nodular fasciitis is a self-limited, benign soft tissue tumor composed of fibroblasts and myofibroblasts that typically afflicts younger patients and rarely presents in the hand.
  • Because of its presentation, it can be easily mistaken for a malignant neoplasm.

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  • (PMID = 18725954.001).
  • [ISSN] 1937-5719
  • [Journal-full-title] Eplasty
  • [ISO-abbreviation] Eplasty
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2491338
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31. Li JM, Yang ZP, Li ZF, Li X, Carter SR: Knee reconstruction with preservation of the meniscus in tibial giant cell tumor. Clin Orthop Relat Res; 2008 Dec;466(12):3101-7
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  • [Title] Knee reconstruction with preservation of the meniscus in tibial giant cell tumor.
  • Giant cell tumor of bone sometimes is an aggressive benign skeletal tumor.
  • Thus, maintaining joint function and achieving adequately wide resection introduces contradictory surgical goals.
  • We reconstructed 13 knees preserving the meniscus and reconstructing the tibial plateau with an iliac plate autograft after resection of a giant cell tumor involving one tibial plateau.
  • While resecting the tumor, the normal anatomic structures of the knee can be preserved or restored in many patients.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Reconstructive Surgical Procedures / methods
  • [MeSH-minor] Adult. Bone Transplantation. Female. Humans. Ilium / transplantation. Male. Menisci, Tibial. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Tibia. Transplantation, Autologous. Young Adult

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  • (PMID = 18830792.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2628220
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32. Zhou WQ, Yin HL, Zhang ZY, Yi XM, Ge JP, Zhou SG, Cheng W, Wei W, Ma HQ, Ma HH, Gao JP: [Expression of VEGF in prostate cancer and its correlation with ET-1]. Zhonghua Nan Ke Xue; 2008 Nov;14(11):987-92
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  • OBJECTIVE: To investigate the expressions of VEGF in prostate cancer (PCa) and benign prostatic hyperplasia (BPH), their clinical significance and their relationship with that of ET-1.
  • VEGF and ET-1 may play a joint role in its development and progression.
  • [MeSH-minor] Aged. Aged, 80 and over. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Prostatic Hyperplasia / metabolism. Prostatic Hyperplasia / pathology

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  • (PMID = 19102498.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Endothelin-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1
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33. Batra PS, Luong A, Kanowitz SJ, Sade B, Lee J, Lanza DC, Citardi MJ: Outcomes of minimally invasive endoscopic resection of anterior skull base neoplasms. Laryngoscope; 2010 Jan;120(1):9-16
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  • Malignant and benign tumors were managed in 25 (80.6%) and six (19.4%) cases, respectively.
  • American Joint Committee on Cancer tumor staging was T3N0M0 and T4N0M0 in 14 (56%) and 11 (44%) of the malignant cases, respectively.
  • CONCLUSIONS: This study validated technical feasibility of MIER for diversity of benign and malignant ASB histopathology.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / surgery. Carcinoma, Squamous Cell / surgery. Esthesioneuroblastoma, Olfactory / surgery. Feasibility Studies. Female. Follow-Up Studies. Humans. Male. Melanoma / surgery. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 19877265.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Sim IW, Tse LF, Ek ET, Powell GJ, Choong PF: Salvaging the limb salvage: management of complications following endoprosthetic reconstruction for tumours around the knee. Eur J Surg Oncol; 2007 Aug;33(6):796-802
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  • Tumour types included 38 primary musculoskeletal malignancies, 8 metastatic tumours, 2 bony lymphomas and 2 benign lesions.
  • [MeSH-major] Arthroplasty, Replacement, Knee. Joint Diseases / surgery. Knee Joint / surgery. Limb Salvage. Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Amputation. Bone Neoplasms / surgery. Female. Follow-Up Studies. Humans. Intraoperative Complications. Joint Prosthesis. Male. Middle Aged. Muscle Neoplasms / surgery. Neoplasm Metastasis. Popliteal Artery / injuries. Postoperative Complications. Prosthesis Failure. Reoperation. Retrospective Studies. Surgical Wound Infection / etiology. Survival Rate. Treatment Outcome

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  • (PMID = 17291709.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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35. Balke M, Streitbuerger A, Budny T, Henrichs M, Gosheger G, Hardes J: Treatment and outcome of giant cell tumors of the pelvis. Acta Orthop; 2009 Oct;80(5):590-6
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  • METHODS: 20 patients with histologically benign GCT of the pelvis were included in this study.
  • RESULTS: 1 patient with a pubic tumor developed a local recurrence 1 year after intralesional resection and additional curettage of the margins.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Pelvic Bones
  • [MeSH-minor] Adult. Aged. Bone Cements. Bone Transplantation. Curettage. Embolization, Therapeutic / methods. Female. Follow-Up Studies. Humans. Ilium / pathology. Ilium / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 19916695.001).
  • [ISSN] 1745-3682
  • [Journal-full-title] Acta orthopaedica
  • [ISO-abbreviation] Acta Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bone Cements
  • [Other-IDs] NLM/ PMC2823344
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36. Schwartz AJ, Kabo JM, Eilber FC, Eilber FR, Eckardt JJ: Cemented distal femoral endoprostheses for musculoskeletal tumor: improved survival of modular versus custom implants. Clin Orthop Relat Res; 2010 Aug;468(8):2198-210
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  • [Title] Cemented distal femoral endoprostheses for musculoskeletal tumor: improved survival of modular versus custom implants.
  • We excluded two patients with cementless implants, 27 with expandable prostheses, and 39 who had a nontumor diagnosis.
  • The tumor was classified as Stage IIA/IIB in 122 patients, Stage IA/IB or benign in 43, and Stage III or metastatic in 21.
  • [MeSH-major] Bone Neoplasms / surgery. Femur / surgery. Joint Prosthesis. Prosthesis Failure. Reconstructive Surgical Procedures / instrumentation
  • [MeSH-minor] Adolescent. Adult. Aged. Cementation. Child. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prosthesis Design. Reoperation. Retrospective Studies. Young Adult

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  • (PMID = 20033359.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2895832
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37. Al Yami A, Griffin AM, Ferguson PC, Catton CN, Chung PW, Bell RS, Wunder JS, O'Sullivan B: Positive surgical margins in soft tissue sarcoma treated with preoperative radiation: is a postoperative boost necessary? Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):1191-7
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  • There was no difference in baseline tumor characteristics between the two groups.
  • Given that higher radiation doses placed patients at greater risk for late complications such as fracture, fibrosis, edema, and joint stiffness, judicious avoidance of the postoperative boost while maintaining an equivalent rate of local control can reduce the risk of these difficult-to-treat morbidities.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Amputation. Female. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / prevention & control. Histiocytoma, Benign Fibrous / radiotherapy. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / pathology. Leiomyosarcoma / prevention & control. Leiomyosarcoma / radiotherapy. Leiomyosarcoma / surgery. Limb Salvage. Liposarcoma / pathology. Liposarcoma / prevention & control. Liposarcoma / radiotherapy. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Neoplasm, Residual. Postoperative Care. Radiotherapy Dosage. Retreatment. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):959; author reply 959-60 [21621120.001]
  • (PMID = 20056340.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Puhaindran ME, Healey JH, Athanasian EA: Single ray amputation for tumors of the hand. Clin Orthop Relat Res; 2010 May;468(5):1390-5
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  • The role of this procedure in the management of aggressive benign or malignant hand tumors has been described only in case reports and small case series.
  • The other was treated with radiotherapy alone, as local tumor control would have required a hand amputation.
  • Functional assessment based on the Musculoskeletal Tumor Society staging system showed an average of 27.5 (range, 21-30).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
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  • [Other-IDs] NLM/ PMC2853661
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39. Jeys LM, Suneja R, Chami G, Grimer RJ, Carter SR, Tillman RM: Impending fractures in giant cell tumours of the distal femur: incidence and outcome. Int Orthop; 2006 Apr;30(2):135-8
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  • Giant cell tumours are rare bone tumours that are characteristically benign but locally aggressive, most frequently occurring in the distal femur with pathological fractures being common.
  • [MeSH-major] Femoral Fractures / epidemiology. Femoral Fractures / physiopathology. Femoral Neoplasms / physiopathology. Giant Cell Tumor of Bone / physiopathology
  • [MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Female. Humans. Incidence. Male. Middle Aged. Neoplasm Recurrence, Local. Prospective Studies. Risk Factors

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40. Yanagawa T, Watanabe H, Shinozaki T, Takagishi K: Curettage of benign bone tumors without grafts gives sufficient bone strength. Acta Orthop; 2009 Feb;80(1):9-13
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  • [Title] Curettage of benign bone tumors without grafts gives sufficient bone strength.
  • BACKGROUND AND PURPOSE: The defect that results after curettage of a bone tumor is usually filled in the same way.
  • We report the outcome in patients with benign bone tumors that were treated with curettage but no filling.
  • PATIENTS AND METHODS: We retrospectively studied 78 patients (mean age at the time of operation was 27 (6-73) years, 44 men) who had had a benign bone tumor curetted with no filling of the defect.
  • The commonest tumor types were giant cell tumor of bone (27), fibrous dysplasia (13), enchondroma (9), and simple bone cyst (7).
  • Local recurrence occurred in 9 patients; 7 of them had a giant cell tumor.
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Cysts / surgery. Bone Remodeling / physiology. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Humans. Middle Aged. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19234882.001).
  • [ISSN] 1745-3682
  • [Journal-full-title] Acta orthopaedica
  • [ISO-abbreviation] Acta Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  • [Other-IDs] NLM/ PMC2823236
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41. Lehnhardt M, Daigeler A, Homann HH, Hauser J, Langer S, Steinsträsser L, Soimaru C, Puls A, Steinau HU: [Importance of specialized centers in diagnosis and treatment of extremity-soft tissue sarcomas. Review of 603 cases]. Chirurg; 2009 Apr;80(4):341-7
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  • [Title] [Importance of specialized centers in diagnosis and treatment of extremity-soft tissue sarcomas. Review of 603 cases].
  • Correct histopathologic diagnosis is essential for adequate treatment of soft tissue sarcomas.
  • Due to the disorder's rarity, multitude of subgroups, sometimes varying histopathologic appearance, and occasionally inadequate biopsy specimens, diagnosis and grading are challenging.
  • The records of 603 patients with soft tissue tumors of the extremities were reviewed concerning mismatches in primary and definite diagnoses relating to entity, evaluation of primary or recurrent tumor specimens, and the diagnosing pathology institution.
  • In the eight most frequent sarcoma types, malignant peripheral nerve sheath tumors and leiomyosarcoma had the highest rates of false primary diagnosis, 78.4% and 74.2% of cases, respectively.
  • [MeSH-major] Cancer Care Facilities. Extremities / surgery. Hospitals, Special. Hospitals, University. Sarcoma / diagnosis. Sarcoma / surgery. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Diagnostic Errors. Female. Germany. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / diagnosis. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / diagnosis. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Staging. Nerve Sheath Neoplasms / diagnosis. Nerve Sheath Neoplasms / pathology. Nerve Sheath Neoplasms / surgery. Radiotherapy, Adjuvant. Referral and Consultation. Retrospective Studies. Young Adult

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  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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42. Jawad MU, Scully SP: In brief: classifications in brief: enneking classification: benign and malignant tumors of the musculoskeletal system. Clin Orthop Relat Res; 2010 Jul;468(7):2000-2
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  • [Title] In brief: classifications in brief: enneking classification: benign and malignant tumors of the musculoskeletal system.
  • [MeSH-minor] Humans. Neoplasm Metastasis. Neoplasm Staging

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  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
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  • [Other-IDs] NLM/ PMC2882012
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43. Skubitz KM, Manivel JC: Giant cell tumor of the uterus: case report and response to chemotherapy. BMC Cancer; 2007;7:46
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  • [Title] Giant cell tumor of the uterus: case report and response to chemotherapy.
  • BACKGROUND: Giant cell tumor (GCT) is usually a benign but locally aggressive primary bone neoplasm in which monocytic macrophage/osteoclast precursor cells and multinucleated osteoclast-like giant cells infiltrate the tumor.
  • The etiology of GCT is unknown, however the tumor cells of GCT have been reported to produce chemoattractants that can attract osteoclasts and osteoclast precursors.
  • [MeSH-minor] Angiogenesis Inhibitors / administration & dosage. Antibiotics, Antineoplastic / administration & dosage. Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Humanized. Antineoplastic Agents, Alkylating / administration & dosage. Bevacizumab. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Humans. Hysterectomy. Ifosfamide / administration & dosage. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Middle Aged. Treatment Outcome

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  • (PMID = 17359524.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibiotics, Antineoplastic; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents, Alkylating; 2S9ZZM9Q9V / Bevacizumab; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
  • [Number-of-references] 57
  • [Other-IDs] NLM/ PMC1832205
  •  go-up   go-down


44. Brisse H, Orbach D, Klijanienko J, Fréneaux P, Neuenschwander S: Imaging and diagnostic strategy of soft tissue tumors in children. Eur Radiol; 2006 May;16(5):1147-64
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  • The diagnosis of a soft tissue mass in children is a common clinical situation.
  • Most of the lesions are benign and can be treated conservatively or by non-mutilating surgery.
  • Nevertheless, the possibility of a malignant soft tissue tumor must be systematically considered.
  • The most frequent benign soft tissue lesions in children are vascular lesions, fibrous and fibrohistiocytic tumors and pseudotumors, whereas rhabdomyosarcomas account for 50% of all soft tissue sarcomas.
  • A child presenting an atypical soft tissue mass should be managed by a multidisciplinary centre, and primary resection must be proscribed until a definite diagnosis has been established.
  • The role of imaging is essential either to confirm the benign nature of the mass or to give arguments to perform a diagnostic biopsy.
  • Clinical examination, conventional radiography and ultrasound with Doppler represent the first-line examinations and are sometimes sufficient to assess a diagnosis.
  • [MeSH-major] Diagnostic Imaging. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Age Factors. Child. Child, Preschool. Decision Trees. Humans. Infant. Infant, Newborn. Neoplasm Staging

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  • (PMID = 16411083.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 108
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45. Bakotic B, Ackerman AB: Staging of melanoma: a critique in historical perspective: part I. Am J Dermatopathol; 2005 Apr;27(2):160-4
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  • That the method employed for achieving that desideratum, which had as its animating force a longing to determine prognosis for an individual patient with that malignant neoplasm, failed miserably can be inferred from the fact that successive efforts every few years by teams of supposed authorities, such as those of the American Joint Committee on Cancer (AJCC), resulted in a new system for staging that bore little resemblance to the one immediately before it or the one that was to come after it.
  • The job of a pathologist is to render an accurate diagnosis (which, in itself, has implications prognostic for a patient, eg, "benign" or "malignant"), not to speculate about prognosis.
  • [MeSH-major] Melanoma / history. Melanoma / pathology. Neoplasm Staging / history. Skin Neoplasms / history. Skin Neoplasms / pathology

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  • (PMID = 15798444.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
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46. Song JW, DU LL, Zhao XW, Jing JX, Han CZ, Cui Y, Liu JW, Hao HL, Wang ZG, Mi ZG: [Expression and clinical significance of nuclear matrix protein 22 and cytokeratin 18 in transitional cell carcinoma of the bladder]. Zhonghua Zhong Liu Za Zhi; 2009 Apr;31(4):274-7
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  • METHODS: Urinary NMP22 and CK18 levels of 293 patients with transitional cell carcinoma of the bladder, 400 patients with non-transitional cell carcinoma of the bladder, and 105 bladder benign disease were analysed by enzyme-linked-immunosorbent assay (ELISA).
  • RESULTS: The levels of urinary NMP22 and CK18 in the patients with transitional cell carcinoma of the bladder (M = 17.3 U/ml, M(CK18) = 484.2 U/L) were significantly higher than those in the non-transitional cell carcinoma of the bladder (M = 6.8 U/ml, M(CK18) = 156.0 U/L) and the benign disease group (M(NMP22) = 2.3 U/ml, M(CK18) = 66.6 U/L) (P < 0.001).
  • The joint sensitivity of the two markers was 91.7%.
  • CONCLUSION: NMP22 and CK18 are useful tumor marker for diagnosis of transitional cell carcinoma of the bladder and for monitoring the state of illness.
  • The joint use of the two markers can improve the sensitivity of cancer detection.
  • NMP22 and CK18 may become a new class of tumor markers, and to be the basis for development of a new assay with an increased efficacy for the detection and treatment of bladder cancer.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / urine. Carcinoma, Renal Cell / urine. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local / urine. Neoplasm Staging. Prognosis. Sensitivity and Specificity. Young Adult

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  • (PMID = 19615282.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-18; 0 / Nuclear Proteins; 0 / nuclear matrix protein 22
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47. Gelabert-González M, García-Allut A: Spinal extradural angiolipoma: report of two cases and review of the literature. Eur Spine J; 2009 Mar;18(3):324-35
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  • Spinal angiolipomas are benign uncommon neoplasm composed of mature lipocytes admixed with abnormal blood vessels.
  • Prior to diagnosis 40.6% of the patients had weakness of the lower limbs.
  • The interval between the initial symptoms and tumor diagnosis ranged from 1 day to 17 years (mean 20.2 months).

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  • (PMID = 19127373.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 99
  • [Other-IDs] NLM/ PMC2899409
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48. Sanatkumar S, Rajagopalan N, Mallikarjunaswamy B, Srinivasalu S, Sudhir NP, Usha K: Benign fibrous histiocytoma of the distal radius with congenital dislocation of the radial head: a case report. J Orthop Surg (Hong Kong); 2005 Apr;13(1):83-7
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  • [Title] Benign fibrous histiocytoma of the distal radius with congenital dislocation of the radial head: a case report.
  • Benign fibrous histiocytoma is such a rare tumour that only a few cases have been reported in the literature.
  • A patient with an apparently benign lesion of the distal radius, along with congenital dislocation of the radial head, was presented at St. John's Medical College Hospital in Bangalore, India.
  • [MeSH-major] Amputation. Bone Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Neoplasm Recurrence, Local / surgery. Orthopedic Procedures / adverse effects
  • [MeSH-minor] Adolescent. Fibula / transplantation. Humans. Joint Dislocations. Male. Radius. Reoperation. Upper Extremity

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  • (PMID = 15872408.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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49. McGough RL, Rutledge J, Lewis VO, Lin PP, Yasko AW: Impact severity of local recurrence in giant cell tumor of bone. Clin Orthop Relat Res; 2005 Sep;438:116-22
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  • [Title] Impact severity of local recurrence in giant cell tumor of bone.
  • We retrospectively reviewed 183 consecutive patients diagnosed with giant cell tumor at the three most common sites (distal femur, proximal tibia, and distal radius) to determine the pattern of local tumor recurrence and the impact severity of the recurrence on adjacent joint function.
  • The primary tumor was treated in all patients with intralesional excision of tumor by curettage.
  • Incomplete initial surgery, a delay in diagnosis of the recurrence of greater than 6 months, and subchondral recurrence of tumor were contributing factors in the failure to salvage the joint.
  • Despite its benign histology, giant cell tumor of bone is an aggressive tumor that demands meticulous attention to surgical detail and close postoperative surveillance for successful local tumor control and durable, joint-preserving function.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / pathology. Neoplasm Recurrence, Local

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  • (PMID = 16131879.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Hauptmann K, Melcher I, Schaser KD: [Differential diagnosis of intramedullary osteosarcomas]. Pathologe; 2008 Nov;29 Suppl 2:240-4
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  • [Title] [Differential diagnosis of intramedullary osteosarcomas].
  • The many subtypes and variants of these tumors often make the differential diagnosis difficult.
  • Low-grade central osteosarcomas are a completely different tumor group.
  • Due to their strong similarity to benign bone tumors they are frequently misdiagnosed as such.
  • The correct diagnosis followed by radical surgery, however, is essential to reduce the high risk of local recurrences, typically seen for of these lesions.
  • [MeSH-minor] Biopsy. Bone and Bones / diagnostic imaging. Bone and Bones / pathology. Diagnosis, Differential. Humans. Neoplasm Recurrence, Local / diagnostic imaging. Neoplasm Recurrence, Local / pathology. Prognosis. Radiography

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  • [Language] ger
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51. Naka N, Joyama S, Tsukamoto Y, Yoshioka K, Hashimoto N, Ujiiye T, Hayashi T, Kawase M, Mano M, Ishiguro S, Myoui A, Ueda T, Yoshikawa H, Araki N, Itoh K: Quantification of SSX mRNA expression in human bone and soft tissue tumors using nucleic acid sequence-based amplification. J Mol Diagn; 2005 May;7(2):187-97
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  • The copy numbers of SSX mRNA per mug of total RNA in tumor tissues were widely distributed, ranging logarithmically from 0.6 to 6.6.
  • We found that malignant tumors showed significantly higher expression of SSX mRNA than benign tumors (P < 0.0001).
  • [MeSH-major] Bone Neoplasms / genetics. Neoplasm Proteins / genetics. RNA, Messenger / analysis. Repressor Proteins / genetics. Self-Sustained Sequence Replication. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Animals. COS Cells. Child. Female. Gene Expression. Humans. Male. Middle Aged. RNA, Neoplasm / analysis. RNA, Neoplasm / metabolism

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  • (PMID = 15858142.001).
  • [ISSN] 1525-1578
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Repressor Proteins; 164289-47-8 / synovial sarcoma X breakpoint proteins
  • [Other-IDs] NLM/ PMC1867521
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52. de Prado Prieto L, García Olmos L, Rodríguez Salvanés F, Otero Puime A: [Evaluation of referrals in primary care]. Aten Primaria; 2005 Feb 28;35(3):146-51
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  • The most common conditions referred, 25.6% of all referrals, are gynecologist check, blindness, other illnesses of subcutaneous cellular tissue, arthrosis, joint pain, diabetes, benign neoplasm of skin, depression and hypoacusis.

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  • (PMID = 15737271.001).
  • [ISSN] 0212-6567
  • [Journal-full-title] Atencion primaria
  • [ISO-abbreviation] Aten Primaria
  • [Language] SPA
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Spain
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53. Weber K, Damron TA, Frassica FJ, Sim FH: Malignant bone tumors. Instr Course Lect; 2008;57:673-88
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  • The primary symptom of a patient with a malignant bone tumor is pain, which often occurs at rest or at night.
  • There are also characteristic findings on physical examination such as swelling or decreased joint range of motion.
  • Patients with a likely malignancy require thorough staging to determine the extent of disease and a well-planned biopsy for accurate diagnosis.
  • Knowledge of specific tumor characteristics and treatment options for osteosarcoma, Ewing's sarcoma, chondrosarcoma, malignant fibrous histiocytoma, chordoma, and adamantinoma is important.
  • Secondary sarcomas can occur in previously benign bone lesions and require aggressive treatment.
  • [MeSH-minor] Global Health. Humans. Morbidity. Neoplasm Staging / methods. Prognosis

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  • (PMID = 18399615.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 42
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54. Mitra R: Osteitis Condensans Ilii. Rheumatol Int; 2010 Jan;30(3):293-6
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  • Osteitis Condensans Ilii (OCI) is a benign cause of axial low back pain.
  • The location of the sclerosis has been traditionally confined to the ilium and may give the false impression of sacro-iliac joint involvement.
  • [MeSH-major] Ilium / pathology. Ilium / physiopathology. Low Back Pain / etiology. Low Back Pain / physiopathology. Osteitis / diagnosis. Osteitis / physiopathology
  • [MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Diagnosis, Differential. Humans. Neoplasm Metastasis / diagnosis. Radiography. Radiology. Sacroiliac Joint / diagnostic imaging. Sacroiliac Joint / pathology. Sacroiliac Joint / physiopathology. Spondylitis, Ankylosing / diagnosis. Steroids / therapeutic use

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  • (PMID = 19711079.001).
  • [ISSN] 1437-160X
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Steroids
  • [Number-of-references] 24
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55. Orhan Z, Oktas B, Yildirim U: An unusual presentation of peroneal neuropathy secondary to pigmented villonodular synovitis: a case report. Knee Surg Sports Traumatol Arthrosc; 2009 May;17(5):518-20
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  • Pigmented villonodular synovitis (PVS) is a benign proliferative disorder of unknown origin that affects synovial joints, most commonly the knee.
  • The joint knee can be affected by localized or diffuse form.
  • Although this disease is categorized as an inflammatory process rather than a neoplasm, it may be locally destructive and involve muscles, tendons, bone and skin.
  • [MeSH-major] Peroneal Neuropathies / diagnosis. Peroneal Neuropathies / etiology. Synovitis, Pigmented Villonodular / complications. Synovitis, Pigmented Villonodular / diagnosis
  • [MeSH-minor] Humans. Knee Joint / pathology. Knee Joint / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Orthopedic Procedures / methods. Peroneal Nerve / pathology. Peroneal Nerve / surgery

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  • (PMID = 19205665.001).
  • [ISSN] 1433-7347
  • [Journal-full-title] Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
  • [ISO-abbreviation] Knee Surg Sports Traumatol Arthrosc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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56. Zustin J, Akpalo H, Gambarotti M, Priemel M, Rueger JM, Luebke AM, Reske D, Lange C, Pueschel K, Lohmann C, Rüther W, Amling M, Alberghini M: Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study. Am J Pathol; 2010 Sep;177(3):1072-8
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  • [Title] Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.
  • Chondromyxoid fibroma represents a rare benign cartilaginous tumor of young patients occurring in a subcortical metaphyseal location.
  • Based on the observed substantial morphological similarity between the cartilage canals and chondromyxoid fibroma, we suggest that the chondromyxoid fibroma represents a neoplasm originating from or mimicking the fetal cartilage canals within the immature cartilage.

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  • (PMID = 20671262.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2928941
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57. Arroud M, Afifi MA, Chbani L, Riffi AA, Bouabdallah Y: Giant-cell tumor of the fourth metacarpal bone in children: case report. J Pediatr Orthop B; 2010 Jan;19(1):86-9
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  • [Title] Giant-cell tumor of the fourth metacarpal bone in children: case report.
  • Giant-cell tumor is a rare benign tumor that generally arises in long bones of the lower extremity in adults.
  • We highlight the rarity of this neoplasm in childhood and discuss epidemiological, clinical, radiological, and therapeutical characteristics of this pathology.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / pathology. Metacarpal Bones / pathology
  • [MeSH-minor] Child. Humans. Male. Metacarpophalangeal Joint / physiopathology. Metacarpophalangeal Joint / surgery. Range of Motion, Articular / physiology. Reconstructive Surgical Procedures. Treatment Outcome

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  • [CommentIn] J Pediatr Orthop B. 2010 May;19(3):285-6 [20375665.001]
  • (PMID = 19898253.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Meller I, Weinbroum A, Bickels J, Dadia S, Nirkin A, Merimsky O, Issakov J, Flusser G, Marouani N, Cohen N, Kollender Y: Fifteen years of bone tumor cryosurgery: a single-center experience of 440 procedures and long-term follow-up. Eur J Surg Oncol; 2008 Aug;34(8):921-7
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  • [Title] Fifteen years of bone tumor cryosurgery: a single-center experience of 440 procedures and long-term follow-up.
  • BACKGROUND: This summary of a single center's extensive cumulative experience in bone tumor cryosurgery assesses the long-term outcome of bone conservation surgery in which adjuvant cryosurgery plays a pivotal role.
  • Two-thirds of the series comprised a variety of primary benign-aggressive and low-grade malignant lesions, and one-third were primary high-grade and metastatic bone tumors.
  • There were three cases of transient nerve palsies in areas other than the sacrum, and four cases of late osteoarthritis of an adjacent joint.
  • The functional outcome for the 372 patients with no evidence of disease was almost 100% "good" and "excellent" (American Musculo-skeletal Tumor Society System).
  • CONCLUSIONS: Bone cryosurgery is a safe and effective limb-, joint- and even epiphysis-sparing surgical technique in suitable types of bone tumors, temporarily or permanently obviating the need for resection surgery.
  • [MeSH-major] Bone Neoplasms / surgery. Cryosurgery. Neoplasm Recurrence, Local

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  • (PMID = 18158228.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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59. Wang Z, Guo Z, Li J, Li XD, Sang HX: Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection. Orthop Surg; 2010 Feb;2(1):19-26
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  • [Title] Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.
  • OBJECTIVE: To evaluate functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.
  • METHODS: Twenty-five patients who underwent Malawer I type resection and reconstruction of the proximal humerus for treatment of malignant or invasive benign tumors from August 1999 to August 2005 were evaluated.
  • A variety of reconstructive procedures, including modular tumor prosthesis, osteoarticular allograft, and allograft-prosthetic composite (APC), were performed after resection of tumor.
  • The modified Musculoskeletal Tumor Society (MSTS) evaluation system was used to assess limb functional outcome.
  • RESULTS: The study group consisted of 10 male and 15 female patients, among which there were 20 malignant and 5 benign tumors.
  • Joint instability and subluxation were serious complications affecting shoulder function in 10 patients.
  • [MeSH-major] Arthroplasty, Replacement / methods. Bone Neoplasms / surgery. Humerus / surgery. Neoplasms, Connective Tissue / surgery. Shoulder Joint / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Lymphoma / mortality. Lymphoma / pathology. Lymphoma / surgery. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Postoperative Complications / epidemiology. Recovery of Function. Retrospective Studies. Treatment Outcome. Young Adult

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  • [Copyright] © 2010 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.
  • (PMID = 22009903.001).
  • [ISSN] 1757-7861
  • [Journal-full-title] Orthopaedic surgery
  • [ISO-abbreviation] Orthop Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Australia
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60. Oliveira RC, Marques KD, Mendonça AR, Mendonça EF, Silva MR, Batista AC, Ribeiro-Rotta RF: Chondrosarcoma of the temporomandibular joint: a case report in a child. J Orofac Pain; 2009;23(3):275-81
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  • [Title] Chondrosarcoma of the temporomandibular joint: a case report in a child.
  • This article reports a rare case of a temporomandibular joint (TMJ) chondrosarcoma in a child.
  • Chondrosarcoma is a malignant cartilaginous neoplasm that resembles synovial chondromatosis.
  • Microscopic findings showed a tumor exhibiting cartilaginous tissue proliferation with cellular pleomorphism, nuclear hyperchromasia, and mixoid changes in the matrix.
  • It is concluded that cartilaginous lesions in the jaws must be regarded with suspicion, since benign and malignant lesions may show similar clinical features.
  • [MeSH-major] Chondrosarcoma / pathology. Temporomandibular Joint Disorders / pathology
  • [MeSH-minor] Child. Cyclin B / analysis. Cyclin B1. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Mandibular Condyle / pathology. Temporomandibular Joint / pathology


61. Donthineni R, Boriani L, Ofluoglu O, Bandiera S: Metastatic behaviour of giant cell tumour of the spine. Int Orthop; 2009 Apr;33(2):497-501
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  • When there is a recurrence of GCT, with or without metastases, the local and possibly the metastases should be biopsied to confirm the original diagnosis.
  • Progression of benign GCT into an aggressive sarcoma has been documented, and the method of management should be altered.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adolescent. Adult. Biopsy, Needle. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Prognosis. Retrospective Studies. Risk Assessment. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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62. Toy PC, White JR, Scarborough MT, Enneking WF, Gibbs CP: Distal femoral osteoarticular allografts: long-term survival, but frequent complications. Clin Orthop Relat Res; 2010 Nov;468(11):2914-23
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  • METHODS: We retrospectively reviewed 26 patients who had osteoarticular allograft reconstruction of the distal femur after resection of a malignant or aggressive benign tumor of bone.
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  • (PMID = 20645036.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
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63. Ozcan C, Apaydin FD, Görür K, Apa DD: Peripheral giant cell granuloma of the mandibular condyle presenting as a preauricular mass. Eur Arch Otorhinolaryngol; 2005 Mar;262(3):178-81
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  • Some rare extraparotid lesions, originating from the temporomandibular joint and the mandible itself, also share the same localization and therefore are to be taken into consideration for the differential diagnosis with parotid lesions.
  • Central GCG (CGCG) is an uncommon benign fibro-osseous lesion generally presenting as an expansible mass with cortical bone defect.
  • The brown tumor of hyperparathyroidism and giant cell tumor must be ruled out because of the microscopic similarities of these lesions.
  • The first case of PGCG of the mandible condyle is presented, and attention is drawn to mandibular diseases for the differential diagnosis of the preauricular mass.
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Tomography, X-Ray Computed

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64. Haque AU, Moatasim A: Giant cell tumor of bone: a neoplasm or a reactive condition? Int J Clin Exp Pathol; 2008;1(6):489-501
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  • [Title] Giant cell tumor of bone: a neoplasm or a reactive condition?
  • Giant cell tumor of bone (GCTB) is a benign but locally aggressive bone tumor of young adults.
  • Malignancy usually does not occur in GCTB and when discover, it usually represents primary bone sarcomas missed at original diagnosis.

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  • (PMID = 18787633.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2480584
  • [Keywords] NOTNLM ; Giant cell tumor / aneurysmal bone cyst / bone / bone matrix / hemorrhage / osteoclast / osteoclastoma / telomerase
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65. Dominkus M, Ruggieri P, Bertoni F, Briccoli A, Picci P, Rocca M, Mercuri M: Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution. Int Orthop; 2006 Dec;30(6):499-504
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  • [Title] Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution.
  • From 1975 to 1997, 649 cases of benign giant cell tumours of the bone were treated at the Istituto Rizzoli.
  • The time interval between the diagnosis and the appearance of the lung metastases ranged from 3 months to 11.9 years.
  • In contrast to previous reports, we could not detect a predominance of the distal radius, but all of the patients had a stage III tumour according to the Enneking criteria of benign lesions.
  • We conclude that even metastatic benign giant cell tumours have an excellent prognosis after adequate resection.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology

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  • (PMID = 16909252.001).
  • [ISSN] 0341-2695
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC3172731
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66. Valdivielso-Ortiz A, Barber I, Soldado F, Aguirre-Canyadell M, Enriquez G: Solitary osteochondroma: spontaneous regression. Pediatr Radiol; 2010 Oct;40(10):1699-701
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  • Osteochondromas are the most common benign bone tumours.
  • [MeSH-major] Bone Neoplasms / diagnostic imaging. Femur / diagnostic imaging. Neoplasm Regression, Spontaneous. Osteochondroma / diagnostic imaging

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  • (PMID = 20714716.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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67. Rehders A, Stoecklein NH, Poremba C, Alexander A, Knoefel WT, Peiper M: Reexcision of soft tissue sarcoma: sufficient local control but increased rate of metastasis. World J Surg; 2009 Dec;33(12):2599-605
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  • BACKGROUND: Assuming a benign tumor, soft tissue sarcomas are often treated by inadequate resection.
  • Therefore, it was our goal to evaluate the results of this treatment with particular respect to residual tumor.
  • The assessed endpoints were local recurrence-free survival, distant metastasis-free survival, and tumor-related mortality.
  • Residual tumor was detected in 43 patients (31%) and was significantly associated with reduced relapse-free and overall survival.
  • CONCLUSIONS: Despite an incomplete initial resection, reexcision enables local control similar to that in patients without residual tumor.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery. Sarcoma / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Reoperation. Survival Analysis. Young Adult

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  • [ErratumIn] World J Surg. 2010 Aug;34(8):1991
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  • (PMID = 19838751.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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68. Nogueira Drumond JM: EFFICACY OF THE ENNEKING STAGING SYSTEM IN RELATION TO TREATING BENIGN BONE TUMORS AND TUMOR-LIKE BONE LESIONS. Rev Bras Ortop; 2010 Jan;45(1):46-52
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  • [Title] EFFICACY OF THE ENNEKING STAGING SYSTEM IN RELATION TO TREATING BENIGN BONE TUMORS AND TUMOR-LIKE BONE LESIONS.
  • OBJECTIVE: To evaluate the efficacy of the Enneking staging system for determining the prognosis, planning surgical treatment and indicating adjuvant therapy for benign bone tumors (BBT) and tumor-like bone lesions (TBL).
  • METHODS: A retrospective multicenter, descriptive, nonrandomized study was carried out on a representative sample comprising a large series of 165 patients with a total of 168 benign bone tumors and tumor-like bone lesions.
  • Tumor recurrence was significantly more frequent (p < 0.001) in the aggressive stage.

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  • (PMID = 27019838.001).
  • [ISSN] 2255-4971
  • [Journal-full-title] Revista brasileira de ortopedia
  • [ISO-abbreviation] Rev Bras Ortop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC4799048
  • [Keywords] NOTNLM ; Bone diseases / Bone neoplasms/diagnosis/epidemiology/pathology/radiography/surgery / Neoplasm staging
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69. Zafatayeff-Hasbani S, Ducou Le Pointe H, Josset P, Damsin JP, Montagne JP: Intra-articular recurrence of benign chondroblastoma with articular involvement at initial presentation--a case report. Eur J Pediatr Surg; 2006 Aug;16(4):291-3
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  • [Title] Intra-articular recurrence of benign chondroblastoma with articular involvement at initial presentation--a case report.
  • [MeSH-minor] Adolescent. Curettage. Epiphyses / pathology. Humans. Knee Joint. Male. Neoplasm Recurrence, Local. Neoplasm Seeding. Soft Tissue Neoplasms / pathology

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  • (PMID = 16981100.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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70. Chamberlain AM, Anderson KL, Hoch B, Trumble TE, Weisstein JS: Benign parosteal osteochondromatous proliferation of the hand originally diagnosed as osteochondroma: a report of two cases and review. Hand (N Y); 2010 Mar;5(1):106-10
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  • [Title] Benign parosteal osteochondromatous proliferation of the hand originally diagnosed as osteochondroma: a report of two cases and review.
  • Bizarre parosteal osteochondromatous proliferation (BPOP) is a rare cartilaginous neoplasm that often presents in the long bones of the hands and feet.
  • BPOP is a benign but locally aggressive fibro-osseous mass that has striking clinical, radiographic, and histologic similarities with osteochondroma.
  • This report presents two cases of BPOP where initial clinical diagnosis of osteochondroma was made even after appropriate imaging and histologic samples were evaluated.

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  • (PMID = 19669236.001).
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  • [ISO-abbreviation] Hand (N Y)
  • [Language] eng
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  • [Publication-country] United States
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71. Siösteen AK, Celsing F, Jacobsson H: FDG uptake in a catheter-related thrombus simulating relapse of lymphoma. Clin Nucl Med; 2005 May;30(5):338-9
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  • There was an area of increased activity posterior to the left sternoclavicular joint, suspected of being a relapse.
  • Focal activity in relation to the tip of a venous catheter is very likely to have a benign etiology.
  • [MeSH-major] Catheterization / adverse effects. Fluorodeoxyglucose F18 / pharmacokinetics. Lymphoma / metabolism. Lymphoma / radionuclide imaging. Neoplasm Recurrence, Local / radionuclide imaging. Venous Thrombosis / etiology. Venous Thrombosis / radionuclide imaging
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Humans. Male. Positron-Emission Tomography / methods. Radiopharmaceuticals / pharmacokinetics

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  • (PMID = 15827407.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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72. Sohn SH, Koh SA, Kim DG, Park SW, Lee KH, Kim MK, Choi JH, Hyun MS: A case of spine origin chondroblastoma metastasis to lung. Cancer Res Treat; 2009 Dec;41(4):241-4
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  • Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur.
  • Unlike previously published examples of metastatic chondroblastoma, these metastasis developed before any operative manipulation of the primary tumor.
  • And primary tumor site was also unusual.

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  • (PMID = 20057972.001).
  • [ISSN] 2005-9256
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2802843
  • [Keywords] NOTNLM ; Chondroblastoma / Lung metastasis / Spine origin
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73. Badar F, Moid I, Waheed F, Zaidi A, Naqvi B, Yunus S: Variables associated with recurrence in breast cancer patients-the Shaukat Khanum Memorial experience. Asian Pac J Cancer Prev; 2005 Jan-Mar;6(1):54-7
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  • Those who presented with benign tumors, carcinoma in situ, or metastases were excluded from the analyses.
  • Age, tumor size, nodal status, menopause, estrogen receptor (ER), and progesterone receptor (PR) status, at the time of presentation, were determined.
  • Tumors were classified according to the TNM classification (American Joint Commission on Cancer (AJCC)-sixth edition), and subsequently, grouped into T1/T2 and T3/T4.
  • [MeSH-major] Breast Neoplasms / pathology. Neoplasm Recurrence, Local
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chi-Square Distribution. Female. Follow-Up Studies. Humans. Logistic Models. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Pakistan / epidemiology. Registries. Risk Factors

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  • (PMID = 15780033.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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74. Fnini S, Labsaili N, Messoudi A, Largab A: [Giant cell tumor of the thumb proximal phalanx: resection-iliac graft and double arthrodesis]. Chir Main; 2008 Feb;27(1):54-7
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  • [Title] [Giant cell tumor of the thumb proximal phalanx: resection-iliac graft and double arthrodesis].
  • Giant cell tumours (GCT) of bone are frequent, with variable behaviour, high risk of recurrence and an often benign histological appearance.
  • After a surgical biopsy, we performed an "en bloc" resection of the first phalanx, with an iliac crest graft reconstruction and a double arthrodesis of the metacarpophalangeal and interphalangeal joint.
  • [MeSH-major] Bone Neoplasms. Giant Cell Tumor of Bone. Thumb
  • [MeSH-minor] Arthrodesis. Biopsy. Bone Nails. Bone Transplantation. Finger Joint. Follow-Up Studies. Fracture Fixation, Internal / instrumentation. Fractures, Spontaneous / etiology. Fractures, Spontaneous / surgery. Humans. Male. Metacarpophalangeal Joint. Middle Aged. Neoplasm Staging. Patient Satisfaction. Time Factors. Treatment Outcome

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  • (PMID = 18248835.001).
  • [ISSN] 1297-3203
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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75. Singh J, James SL, Kroon HM, Woertler K, Anderson SE, Jundt G, Davies AM: Tumour and tumour-like lesions of the patella--a multicentre experience. Eur Radiol; 2009 Mar;19(3):701-12
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  • Of the 59 cases, 46% were non neoplastic, 39% were benign and 15% were malignant.
  • The commonest benign neoplasm was giant cell tumour (GCT) (11 cases).
  • Younger patients were more likely to have a benign neoplasm.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Diagnosis, Differential. Female. Humans. Male. Medical Oncology / methods. Middle Aged. Neoplasm Metastasis. Radiology / methods

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  • [ErratumIn] Eur Radiol. 2010 Mar;20(3):763. Jundt, G [added]
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  • (PMID = 18815789.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
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76. Zhang Y, Forootan SS, Liu D, Barraclough R, Foster CS, Rudland PS, Ke Y: Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients. Prostate Cancer Prostatic Dis; 2007;10(3):293-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The relative levels of AGR2 expression in the malignant cell lines PC-3 and PC-3M were, respectively, 5.3+/-0.1 and 3.8+/-0.2 times that detected in the benign cell line PNT-2.
  • Amongst 34 benign prostate hyperplastic (BPH) cases, 12 (35.3%) were unstained, 18 (52.9%) stained weakly positive and four (11.8%) stained moderately positive.
  • Increased joint Gleason score (GS) was significantly (log rank test, P=0.001) associated with poor patient survival.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / mortality. Biomarkers, Tumor / analysis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / mortality. Proteins / metabolism
  • [MeSH-minor] Aged. Blotting, Western. Cell Line, Tumor. Gene Expression. Humans. Immunohistochemistry. Kaplan-Meier Estimate. Male. Neoplasm Staging. Prostate-Specific Antigen / blood


77. Arbeitsgemeinschaft Knochentumoren, Becker WT, Dohle J, Bernd L, Braun A, Cserhati M, Enderle A, Hovy L, Matejovsky Z, Szendroi M, Trieb K, Tunn PU: Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapy. J Bone Joint Surg Am; 2008 May;90(5):1060-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapy.
  • BACKGROUND: The use of adjuvants after curettage has been well established for the treatment of giant cell tumor of bone.
  • The purpose of this study was to analyze the rates of recurrence following different types of treatment as well as the influence of various factors of tumor presentation on those rates.
  • METHODS: The data regarding benign giant cell tumors of the appendicular skeleton from ten bone tumor centers were evaluated.
  • The recurrence rates associated with the different treatment modalities were analyzed, and hazard ratios for a recurrence were calculated for multiple factors of tumor presentation.
  • The recurrence rate following curettage of a primary tumor without the use of adjuvants (55%) was higher than that following the same treatment of a recurrent tumor (39%) (p = 0.033).
  • CONCLUSIONS: Use of polymethylmethacrylate as an adjuvant significantly reduces the recurrence rate following intralesional treatment of benign giant cell tumors, and it appears to be the therapy of choice for primary as well as recurrent giant cell tumors of bone.
  • The significantly better results following treatment of recurrent tumors without adjuvants compared with the results of the same treatment of primary tumors were probably related to increased surgical thoroughness brought about by the surgeon's awareness of dealing with a riskier tumor.
  • [MeSH-major] Bone Cements / therapeutic use. Bone Neoplasms / therapy. Giant Cell Tumor of Bone / therapy. Neoplasm Recurrence, Local / prevention & control. Polymethyl Methacrylate / therapeutic use
  • [MeSH-minor] Antineoplastic Agents / administration & dosage. Cautery. Combined Modality Therapy. Curettage. Female. Humans. Kaplan-Meier Estimate. Male. Neoplasm, Residual / prevention & control. Phenol / administration & dosage. Proportional Hazards Models. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • Hazardous Substances Data Bank. PHENOL .
  • Hazardous Substances Data Bank. SODIUM PHENOLATE .
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  • (PMID = 18451399.001).
  • [ISSN] 1535-1386
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Bone Cements; 339NCG44TV / Phenol; 9011-14-7 / Polymethyl Methacrylate
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78. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases.
  • BACKGROUND: The diagnosis of retroperitoneal lesions is one of the most difficult areas in surgical pathology.
  • Fine needle aspiration cytology has shown promising role in establishing the diagnosis in this region.
  • OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.
  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).
  • CONCLUSIONS: USG-guided FNAC is an inexpensive, rapid, safe, and accurate procedure for the diagnosis of retroperitoneal masses.

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  • [Cites] Scand J Urol Nephrol. 1974;8(3):223-6 [