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Items 1 to 52 of about 52
1. Nigam S, Gupta SK, Chaturvedi KU: Adenomatoid odontogenic tumor--a rare cause of jaw swelling. Braz Dent J; 2005;16(3):251-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor--a rare cause of jaw swelling.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, characterized histologically by the formation of ductlike structures with amyloid-like deposits.
  • Histogenesis of AOT is still uncertain and it is often considered as a hamartomatous lesion rather than a true neoplasm.
  • AOT has a benign behavior and conservative surgical enucleation or curettage is sufficient.
  • We report a case of AOT in a 15-year-old female who presented with left-sided jaw swelling with tooth resorption.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis
  • [MeSH-minor] Adolescent. Bicuspid / pathology. Biopsy, Fine-Needle. Cuspid / pathology. Diagnosis, Differential. Female. Humans. Incisor / pathology. Tooth Resorption / diagnosis. Tooth, Impacted / diagnosis

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  • (PMID = 16429194.001).
  • [ISSN] 1806-4760
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 8
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2. Mukhopadhyay S, Raha K, Mondal SC: Huge ameloblastoma of jaw-A case report. Indian J Otolaryngol Head Neck Surg; 2005 Jul;57(3):247-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Huge ameloblastoma of jaw-A case report.
  • Ameloblastoma is a tumor of odontogenic epithelium.
  • It is a tumour of intermediate malignant potential which lies in the gray zone between benign and malignant neoplasm.
  • A huge ameloblastoma revealing benign cytological features in FNAC is being reported.Ameloblastoma arises from odontogenic epithelium.
  • This tumor can occur at any age.
  • This tumor shows invasive property and a remarkable tendency of recurrence.
  • Ameloblastic carcinoma is a tumor with microscopic features of ameloblastoma that displays malignant features at cytological level.([2]) It usually has aggressive course.
  • A case of large ameloblastoma with slow clinical course and benign cytological as well as histological features is being reported.

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  • [Cites] Oral Surg Oral Med Oral Pathol. 1984 Feb;57(2):168-76 [6366686.001]
  • (PMID = 23120181.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3451340
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3. Lanza A, Laino L, Rossiello L, Perillo L, Ermo AD, Cirillo N: Clinical Practice: Giant Cell Tumour of the Jaw Mimicking Bone Malignancy on Three-Dimensional Computed Tomography (3D CT) Reconstruction. Open Dent J; 2008;2:73-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical Practice: Giant Cell Tumour of the Jaw Mimicking Bone Malignancy on Three-Dimensional Computed Tomography (3D CT) Reconstruction.
  • Periapical inflammation, cysts and benign tumours, bone malignancies, all of these conditions may show bone resorption on radiograph.
  • Features of the surrounding bone, margins of the lesion, and biological behaviour including tendency to infiltration and root resorption, may represent important criteria for distinguishing benign tumours from their malign counterpart, although the radiographic aspect of the lesion is not always predictive.
  • Therefore a critical differential diagnosis has to be reached to choose the best management.
  • Here, we report a case of giant cell tumour (GCT) whose radiological features by computed tomography (CT) suggested the presence of bone malignancy, whereas the evaluation of a routine OPT scan comforted us about the benign nature of the lesion.
  • A brief review of the literature on such a benign but locally aggressive neoplasm is also provided.

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  • (PMID = 19088886.001).
  • [ISSN] 1874-2106
  • [Journal-full-title] The open dentistry journal
  • [ISO-abbreviation] Open Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC2581533
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4. Singh M, Gupta KC: Surgical treatment of odontogenic keratocyst by enucleation. Contemp Clin Dent; 2010 Oct;1(4):263-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although odontogenic keratocysts (OKCs) are benign, they are often locally destructive and tend to recur after conservative surgical treatment.
  • They must therefore be distinguished from other cysts of the jaw.
  • Histologic examination is essential for diagnosis since the appearances on roentgenograms and at operation usually do not reveal the true nature of the lesion.

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  • (PMID = 22114435.001).
  • [ISSN] 0976-2361
  • [Journal-full-title] Contemporary clinical dentistry
  • [ISO-abbreviation] Contemp Clin Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3220151
  • [Keywords] NOTNLM ; Gorlin syndrome / benign cystic neoplasm / odontogenic keratocyst / radicular cyst
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5. Ruhin-Poncet B, Ghoul-Mazgar S, Hotton D, Capron F, Jaafoura MH, Goubin G, Berdal A: Msx and dlx homeogene expression in epithelial odontogenic tumors. J Histochem Cytochem; 2009 Jan;57(1):69-78

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Epithelial odontogenic tumors are rare jaw pathologies that raise clinical diagnosis and prognosis dilemmas notably between ameloblastomas and clear cell odontogenic carcinomas (CCOCs).
  • Although Msx1 expression imitates normal cell differentiation in these tumors, other genes showed a distinct pattern depending on the type of tumor and the tissue involved.
  • In benign ameloblastomas, ISH localized Dlx3 transcripts and inconstantly detected Msx2 transcripts in epithelial cells.
  • [MeSH-major] Homeodomain Proteins / biosynthesis. Jaw Neoplasms / metabolism. MSX1 Transcription Factor / biosynthesis. Odontogenic Tumors / metabolism. Transcription Factors / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Ameloblastoma / metabolism. Bone Morphogenetic Protein 2 / biosynthesis. Bone Morphogenetic Protein 4 / biosynthesis. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. In Situ Hybridization. Male. Middle Aged. Neoplasm Recurrence, Local. Reverse Transcriptase Polymerase Chain Reaction. Young Adult

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  • (PMID = 18854600.001).
  • [ISSN] 0022-1554
  • [Journal-full-title] The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • [ISO-abbreviation] J. Histochem. Cytochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BMP2 protein, human; 0 / BMP4 protein, human; 0 / Bone Morphogenetic Protein 2; 0 / Bone Morphogenetic Protein 4; 0 / Distal-less homeobox proteins; 0 / Homeodomain Proteins; 0 / MSX1 Transcription Factor; 0 / MSX2 protein; 0 / Transcription Factors
  • [Other-IDs] NLM/ PMC2605714
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6. Bornstein MM, Filippi A, Altermatt HJ, Lambrecht JT, Buser D: [The odontogenic keratocyst--odontogenic cyst or benign tumor?]. Schweiz Monatsschr Zahnmed; 2005;115(2):110-28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The odontogenic keratocyst--odontogenic cyst or benign tumor?].
  • [Transliterated title] Die odontogene Keratozyste--odontogene Zyste oder benigner Tumor?
  • Keratocysts most commonly occur as single lesions in the jaw of otherwise healthy persons.
  • This led to the tentative suggestion that the keratocyst might be a benign cystic neoplasm rather than simply an odontogenic cyst.

  • MedlinePlus Health Information. consumer health - Jaw Injuries and Disorders.
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  • (PMID = 15771334.001).
  • [ISSN] 0256-2855
  • [Journal-full-title] Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia
  • [ISO-abbreviation] Schweiz Monatsschr Zahnmed
  • [Language] FRE; GER
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 68238-35-7 / Keratins
  • [Number-of-references] 69
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7. Dominguete PR, Meyer TN, Alves FA, Bittencourt WS: Juvenile ossifying fibroma of the jaw. Br J Oral Maxillofac Surg; 2008 Sep;46(6):480-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile ossifying fibroma of the jaw.
  • Juvenile ossifying fibroma is a benign lesion with aggressive local growth.
  • [MeSH-major] Fibroma, Ossifying / diagnosis. Mandibular Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 18206279.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Dental Implants
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8. Demicco EG, Deshpande V, Nielsen GP, Kattapuram SV, Rosenberg AE: Well-differentiated osteosarcoma of the jaw bones: a clinicopathologic study of 15 cases. Am J Surg Pathol; 2010 Nov;34(11):1647-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Well-differentiated osteosarcoma of the jaw bones: a clinicopathologic study of 15 cases.
  • Well-differentiated osteosarcoma of the jaw bones is rare, and is often confused with a variety of benign fibroosseous lesions.
  • The tumor cells were intimately related to the surfaces of elongated trabeculae of neoplastic woven bone that lacked osteoblastic rimming.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Oral Surgical Procedures. Radiotherapy, Adjuvant. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • (PMID = 20975343.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Stergiou GC, Zwahlen RA, Grätz KW: [Multiple cemento-ossifying fibromas of the jaw: a very rare diagnosis]. Schweiz Monatsschr Zahnmed; 2007;117(3):236-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multiple cemento-ossifying fibromas of the jaw: a very rare diagnosis].
  • The cemento-ossifying fibromas (COF) of the jaws are well circumscribed, generally slow-growing, benign lesions which enlarge in an expansive manner.
  • Although WHO and some authors regard the cementifying fibroma (CF) as an odontogenic tumor and consider ossifying fibroma (OF) separately as non-odontogenic neoplasm, there is general agreement that CF and OF represent only histologic variants of the same lesion.

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  • (PMID = 17425241.001).
  • [ISSN] 0256-2855
  • [Journal-full-title] Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia
  • [ISO-abbreviation] Schweiz Monatsschr Zahnmed
  • [Language] FRE; GER
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
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10. Said-Al-Naief N, Fernandes R, Louis P, Bell W, Siegal GP: Desmoplastic fibroma of the jaw: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Jan;101(1):82-94

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic fibroma of the jaw: a case report and review of literature.
  • Desmoplastic fibroma is a benign intraosseous neoplasm that is recognized as the intraosseous counterpart of soft tissue fibromatosis in both gnathic and extragnathic sites.
  • [MeSH-major] Fibroma, Desmoplastic / pathology. Jaw Neoplasms / pathology

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  • (PMID = 16360612.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Vimentin
  • [Number-of-references] 70
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11. Kreutzer R, Wohlsein P, Staszyk C, Nowak M, Sill V, Baumgärtner W: Dental benign cementomas in three horses. Vet Pathol; 2007 Jul;44(4):533-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dental benign cementomas in three horses.
  • Cementoma is a very rare odontogenic neoplasm of mesenchymal origin.
  • Clinically, in 3 horses, multiple bony enlargements of the upper and lower jaw extending into the oral cavity were observed.
  • Cells, resembling cementoblasts, lined irregularly shaped lacunae, which were present in the tumor tissue, and showed minimal cellular pleomorphism.
  • However, due to their high degree of differentiation, hypercementosis must be considered as a differential diagnosis.

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  • (PMID = 17606518.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Dos Santos JN, Oliveira GQ, Gurgel CA, de Souza RO, Sales CB, de Aguiar Pires Valença Neto A, Ramos EA: Altered expression of cytokeratins in primary, recurrent and syndrome keratocystic odontogenic tumors. J Mol Histol; 2009 Aug;40(4):269-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Keratocystic odontogenic tumor (KOT) is a benign cystic tumor that affects the jaw bones and may be associated with the nevoid basal cell carcinoma syndrome (NBCCS).
  • [MeSH-major] Basal Cell Nevus Syndrome / pathology. Jaw Neoplasms / pathology. Keratins / biosynthesis. Neoplasm Recurrence, Local / pathology. Odontogenic Cysts / pathology

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  • (PMID = 19915949.001).
  • [ISSN] 1567-2387
  • [Journal-full-title] Journal of molecular histology
  • [ISO-abbreviation] J. Mol. Histol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 68238-35-7 / Keratins
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13. Mintz S, Velez I: Central ossifying fibroma: an analysis of 20 cases and review of the literature. Quintessence Int; 2007 Mar;38(3):221-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Central ossifying fibroma is the most common benign fibro-osseous neoplasm of the jaw.
  • [MeSH-major] Fibroma, Ossifying / pathology. Jaw Neoplasms / pathology

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  • (PMID = 17333999.001).
  • [ISSN] 0033-6572
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 13
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14. Sedghizadeh PP, Wong D, Shuler CF, Linz V, Kalmar JR, Allen CM: Multifocal calcifying epithelial odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Aug;104(2):e30-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal calcifying epithelial odontogenic tumor.
  • The calcifying epithelial odontogenic tumor (CEOT), or Pindborg tumor, is a rare and benign odontogenic neoplasm that affects the jaw.
  • The most common manifestation of CEOT is a unifocal or localized lesion of the involved jaw, which may appear clinically as a hard tissue swelling and radiographically as a mixed radiolucent-radiopaque mass.
  • [MeSH-major] Jaw Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Rare Diseases

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  • (PMID = 17630096.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Ledesma-Montes C, Gorlin RJ, Shear M, Prae Torius F, Mosqueda-Taylor A, Altini M, Unni K, Paes de Almeida O, Carlos-Bregni R, Romero de León E, Phillips V, Delgado-Azañero W, Meneses-García A: International collaborative study on ghost cell odontogenic tumours: calcifying cystic odontogenic tumour, dentinogenic ghost cell tumour and ghost cell odontogenic carcinoma. J Oral Pathol Med; 2008 May;37(5):302-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • (iii) ameloblastomatous proliferating; and (iv) CCOT associated with benign odontogenic tumours other than odontomas.
  • [MeSH-major] Jaw Neoplasms / classification. Jaw Neoplasms / pathology. Odontogenic Cyst, Calcifying / classification. Odontogenic Cyst, Calcifying / pathology. Odontogenic Tumors / classification. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Cell Transformation, Neoplastic. Child. Female. Humans. International Cooperation. Keratins. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Sex Distribution. Tooth, Unerupted / complications

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  • (PMID = 18221328.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 68238-35-7 / Keratins
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16. Hyun HK, Hong SD, Kim JW: Recurrent keratocystic odontogenic tumor in the mandible: a case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Aug;108(2):e7-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent keratocystic odontogenic tumor in the mandible: a case report and literature review.
  • Keratocystic odontogenic tumor is characterized by benign intraosseous neoplasm of odontogenic origin with high recurrence rates.
  • Conservative approaches have some advantages in that they avoid adverse effects on the development of involved teeth and the jaw when the patient is young, although aggressive methods, including surgical resection, can be recommended considering the nature of the neoplasm.
  • Here we report a case of a 7-year-old patient with a recurrent keratocystic odontogenic tumor treated by marsupialization for normal development of the involved teeth.
  • [MeSH-major] Mandibular Neoplasms / surgery. Neoplasm Recurrence, Local / pathology. Odontogenic Cysts / surgery. Odontogenic Tumors / surgery

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  • (PMID = 19615649.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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17. Mortellaro C, Berrone M, Turatti G, Rimondini L, Brach Del Prever A, Canavese F, Pucci A, Farronato G: Odontogenic tumors in childhood: a retrospective study of 86 treated cases. Importance of a correct histopathologic diagnosis. J Craniofac Surg; 2008 Jul;19(4):1173-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic tumors in childhood: a retrospective study of 86 treated cases. Importance of a correct histopathologic diagnosis.
  • The odontogenic tumors grow in the jaw, through the haversian system, without metastasis but with and high probability of relapse.
  • The percent of diagnosed cases that were benign was 98.8%, and just one case of malign neoplasm is reported.
  • The most frequent tumor accounted for in the reported sample was odontoma (39.5%) followed by odontogenic fibroma (12.8%).
  • Early diagnosis, together with a correct histologic diagnosis, allows a preservative and effective surgical treatment and is necessary to reduce the risk of relapse.
  • [MeSH-minor] Adolescent. Age Distribution. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Male. Retrospective Studies. Sex Factors

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  • (PMID = 18650755.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Lardinois D, Weder W, Roudas M, von Schulthess GK, Tutic M, Moch H, Stahel RA, Steinert HC: Etiology of solitary extrapulmonary positron emission tomography and computed tomography findings in patients with lung cancer. J Clin Oncol; 2005 Oct 1;23(28):6846-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A diagnosis was obtained in 69 of these patients, including 37 (54%) with solitary metastases and 32 (46%) with lesions unrelated to the lung primary.
  • Histopathologic examinations of these 32 lesions revealed a second clinically unsuspected malignancy or a recurrence of a previous diagnosed carcinoma in six patients (19%) and a benign tumor or inflammatory lesion in 26 patients (81%).
  • Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture.
  • CONCLUSION: Solitary extrapulmonary FDG accumulations in patients with newly diagnosed lung cancer should be analyzed critically for correct staging and optimal therapy, given that up to half of the lesions may represent unrelated malignancies or benign disease.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Lung Neoplasms / radionuclide imaging. Neoplasm Metastasis / radionuclide imaging. Positron-Emission Tomography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Fluorodeoxyglucose F18. Humans. Inflammation. Male. Middle Aged. Neoplasm Staging. Prospective Studies. Radiopharmaceuticals. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 16192576.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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19. Pimenta FJ, Gontijo Silveira LF, Tavares GC, Silva AC, Perdigão PF, Castro WH, Gomez MV, Teh BT, De Marco L, Gomez RS: HRPT2 gene alterations in ossifying fibroma of the jaws. Oral Oncol; 2006 Aug;42(7):735-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ossifying fibroma (OF) is a benign neoplasm related to bone characterized by a progressive enlargement of the affected jaw.
  • Recently, the candidate tumor suppressor gene HRPT2 was identified and alterations in this gene were related with the Hyperparathyroidism-jaw tumor syndrome that is characterized by parathyroid adenoma or carcinoma, fibro-osseous lesions (mainly OF) of the jaws, and renal lesions.
  • [MeSH-major] Fibroma, Ossifying / genetics. Genes, Tumor Suppressor. Mandibular Neoplasms / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Female. Gene Expression. Humans. Male. Middle Aged. Mutation. RNA, Messenger / genetics. RNA, Neoplasm / genetics. Reverse Transcriptase Polymerase Chain Reaction / methods

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  • (PMID = 16458039.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CDC73 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Tumor Suppressor Proteins
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20. Ritwik P, Brannon RB: Peripheral odontogenic fibroma: a clinicopathologic study of 151 cases and review of the literature with special emphasis on recurrence. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Sep;110(3):357-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: The peripheral odontogenic fibroma (POdF) is a rare benign neoplasm of odontogenic origin with limited data on recurrence.
  • RESULTS: POdF should be considered a mixed odontogenic tumor because it is composed of active odontogenic epithelial and ectomesenchymal components.
  • [MeSH-major] Fibroma / pathology. Jaw Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Child. Child, Preschool. Follow-Up Studies. Humans. Infant. Infant, Newborn. Logistic Models. Male. Middle Aged. Mixed Tumor, Malignant / pathology. Sex Distribution. Time Factors. Young Adult

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20674403.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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21. Bradley KJ, Cavaco BM, Bowl MR, Harding B, Cranston T, Fratter C, Besser GM, Conceição Pereira M, Davie MW, Dudley N, Leite V, Sadler GP, Seller A, Thakker RV: Parafibromin mutations in hereditary hyperparathyroidism syndromes and parathyroid tumours. Clin Endocrinol (Oxf); 2006 Mar;64(3):299-306
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To investigate two patients with the hyperparathyroidism-jaw tumour (HPT-JT) syndrome and three patients with familial isolated hyperparathyroidism (FIHP), together with 31 parathyroid tumours (2 HPT-JT, 2 FIHP and 27 sporadic) for HRPT2 mutations.
  • DESIGN: Leukocyte and tumor DNA was used with HRPT2-specific primers for polymerase chain reaction amplification of the 17 exons and their splice junctions, and the DNA sequences of the polymerase chain reaction products determined.
  • The 27 sporadic benign parathyroid tumours did not harbour any HRPT2 somatic mutations.
  • [MeSH-major] Hyperparathyroidism / genetics. Jaw Neoplasms / genetics. Parathyroid Neoplasms / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adult. Child. DNA, Neoplasm / genetics. Family Health. Female. Gene Frequency. Humans. Loss of Heterozygosity / genetics. Male. Middle Aged. Mutation / genetics. Pedigree. Polymorphism, Genetic / genetics. Syndrome

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  • (PMID = 16487440.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G9825289
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CDC73 protein, human; 0 / DNA, Neoplasm; 0 / Tumor Suppressor Proteins
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22. Jones AC, Prihoda TJ, Kacher JE, Odingo NA, Freedman PD: Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Nov;102(5):639-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoblastoma is a benign neoplasm of bone characterized by a proliferation of osteoblasts forming bone trabeculae set in a vascularized fibrous connective tissue stroma.
  • We report 24 examples of this neoplasm arising in the maxilla and mandible and compare the clinical and radiographic characteristics of this neoplasm to 53 previously reported examples of osteoblastoma and osteoid osteoma in the jaws.
  • We also provide a rationale for use of the term "osteoblastoma" for any benign osteoblastic neoplasm arising in the jaws.
  • [MeSH-major] Jaw Neoplasms / pathology. Osteoblastoma / pathology. Osteoma, Osteoid / pathology

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  • (PMID = 17052641.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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23. Shekarkhar MJ, Tabei SZ, Kumar PV, Hashemi SB: Cytologic findings in calcifying epithelial odontogenic tumor: a case report. Acta Cytol; 2005 Sep-Oct;49(5):533-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic findings in calcifying epithelial odontogenic tumor: a case report.
  • BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT), or Pindborg's tumor, is a rare, benign, odontogenic neoplasm first described by Pindborg in 1955.
  • CONCLUSION: FNA findings of calcifying epithelial odontogenic tumor have been described rarely.
  • The clusters of epithelial cells with prominent nucleoli are mistaken for features of a malignant tumor.
  • [MeSH-major] Calcinosis / pathology. Epithelial Cells / pathology. Jaw Neoplasms / pathology. Maxillary Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology. Palatal Neoplasms / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Diagnostic Errors / prevention & control. Female. Humans. Maxilla / pathology. Maxilla / radiography. Maxillary Sinus / pathology. Maxillary Sinus / radiography. Middle Aged. Palate, Hard / pathology. Palate, Hard / radiography

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  • (PMID = 16334032.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Mendes RA, Carvalho JF, van der Waal I: Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol; 2010 Apr;46(4):219-25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features.
  • Keratocystic odontogenic tumor (KCOT), formerly referred to as odontogenic keratocyst, is a benign neoplasm of odontogenic origin which may present an aggressive and infiltrative behavior leading to high recurrence rates.
  • Although prognostic factors based on clinico-pathologic and immunohistochemical findings for determining the potential for recurrence of KCOT still remains unclear, its use for determining the potential for recurrence of KCOT after surgical treatment may become important to successfully manage this neoplasm's aggressive behavior.
  • The key element for future management of KCOTs will probably be based on thorough knowledge of the biological basis of this tumor, thereby enabling a more tailored treatment approach.
  • [MeSH-major] Jaw Neoplasms. Neoplasm Recurrence, Local. Odontogenic Cysts. Odontogenic Tumors
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male. Prognosis

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20189443.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
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25. Baumhoer D, Pförtner R, Mohr C, Jundt G: Tubulopapillary hidradenoma-like tumor of the mandible. Int J Oral Maxillofac Surg; 2009 Aug;38(8):903-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tubulopapillary hidradenoma-like tumor of the mandible.
  • Tubulopapillary hidradenomas are uncommon benign tumors of the dermis, most commonly occurring in the skin of the head or of the extremities.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Mandibular Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Curettage. Diagnosis, Differential. Epithelial Cells / pathology. Follow-Up Studies. Humans. Jaw Cysts / diagnosis. Male. Mandible / surgery. Mandibular Diseases / diagnosis. Neoplasm Recurrence, Local / pathology. Osteolysis / diagnosis. Osteotomy

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  • (PMID = 19375892.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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26. Matijević M, Leović D, Popić B, Zubcić V, Kopić V, Prlić A, Siber S, Dinjar K: The importance of thorough preoperative diagnostics of maxillary ameloblastoma: report of three cases. Coll Antropol; 2010 Dec;34(4):1445-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma, especially maxillary, is a rare benign neoplasm of odontogenic origin.
  • Diagnosis of significant number of lesions is usually established postoperatively, because ameloblastoma, especially the unicystic form, mimics wide range of more frequent jaw lesions.
  • [MeSH-major] Ameloblastoma / diagnosis. Maxillary Neoplasms / diagnosis

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  • (PMID = 21874736.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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27. Chaudhry J, Rawal SY, Anderson KM, Rawal YB: Cancellous osteoma of the maxillary tuberosity: case report. Gen Dent; 2009 Jul-Aug;57(4):427-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The osteoma is a benign, bone-forming lesion that is not considered a true neoplasm.
  • Jaw lesions may cause facial deformity and impair oral function.
  • This article describes a cancellous osteoma of the left maxillary molar and tuberosity area and differentiates it from other benign and malignant lesions, including the parosteal osteosarcoma.

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  • (PMID = 19903627.001).
  • [ISSN] 0363-6771
  • [Journal-full-title] General dentistry
  • [ISO-abbreviation] Gen Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Perdigão PF, Stergiopoulos SG, De Marco L, Matyakhina L, Boikos SA, Gomez RS, Pimenta FJ, Stratakis CA: Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas. Genes Chromosomes Cancer; 2005 Oct;44(2):204-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Odontogenic myxomas are rare benign neoplasms affecting the jaw.
  • Myxomas of bones and other sites occur as part of Carney complex (CNC), a multiple neoplasia syndrome caused by mutations in the PRKAR1A gene, which codes for the regulatory subunit of protein kinase A (PKA).
  • Mutations of the coding region of the PRKAR1A gene were identified in 2 tumors; both these lesions showed no or significantly decreased immunostaining of PRKAR1A in the tumor compared to that in the surrounding normal tissue.
  • Of the remaining tumors, 7 of the 15 without mutations showed almost no PRKAR1A in the tumor cells, whereas IHC showed that the protein was abundant in nontumorous cells.
  • [MeSH-minor] Cyclic AMP-Dependent Protein Kinase RIalpha Subunit. Cyclic AMP-Dependent Protein Kinases. DNA, Neoplasm / genetics. Humans. Immunohistochemistry. Mutation

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  • (PMID = 16001434.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / DNA, Neoplasm; 0 / PRKAR1A protein, human; 0 / Proteins; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
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29. Sioud S, Bertolus C, Gruffaz F, Ghoul S, Menard P, Bertrand JC, Ruhin B: [Giant-cell tumors: three recurrent cases in young patients]. Rev Stomatol Chir Maxillofac; 2007 Apr;108(2):131-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Tumeurs à cellules géantes: à propos de trois cas récidivants chez des sujets jeunes.
  • INTRODUCTION: True giant-cell tumor is a rare jaw osteolytic benign tumor belonging to the larger family of giant-cell tumors.
  • We emphasize the importance of early definitive diagnosis based on rigorous clinical and radiological confrontations.
  • Because of its benign nature, the most conservative surgical treatment (tumorectomy-curettage) is generally proposed for the young patient.
  • [MeSH-major] Giant Cell Tumor of Bone / pathology. Jaw Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Male. Neoplasm Recurrence, Local

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  • (PMID = 17320127.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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30. Black CC, Addante RR, Mohila CA: Intraosseous ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Nov;110(5):585-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastomas are benign slow-growing aggressive neoplasms with a poorly understood potential for rare metastasis.
  • Treatment planning for a given tumor includes consideration of location, primary versus recurrent, size, presence of cortical perforation, and age and health of the patient.
  • [MeSH-major] Ameloblastoma / diagnosis. Jaw Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Age Factors. Ameloblasts / pathology. Child. Dental Enamel / pathology. Epithelium / pathology. Humans. Mesoderm / pathology. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Patient Care Planning. Young Adult

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • [CommentIn] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 May;111(5):536; author reply 536-8 [21306924.001]
  • (PMID = 20580278.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Zhang B, Zhang J, Huang HZ, Chen WL, Tao Q, Zeng DL, Zhang LT, Xu JH: Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity. J Oral Pathol Med; 2009 Oct;38(9):731-6
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  • BACKGROUND: Ameloblastoma is an odontogenic benign tumor characterized by local invasiveness and most of its local recurrences clinically result from local invasion.
  • In vitro, the invasive activity of tumor cells was assayed in transwell cell culture chamber.
  • Accordingly, potential of in vitro cell invasion, adhesion and in vivo tumor invasion were also significantly lower in the treatment group than in the control group.
  • [MeSH-major] Ameloblastoma / enzymology. Jaw Neoplasms / enzymology. Matrix Metalloproteinase Inhibitors. Tissue Inhibitor of Metalloproteinase-2 / pharmacology
  • [MeSH-minor] Animals. Humans. Matrix Metalloproteinase 2 / physiology. Mice. Mice, Inbred BALB C. Mice, Nude. Neoplasm Invasiveness. Neoplasm Transplantation. Tumor Cells, Cultured

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  • (PMID = 19473446.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Matrix Metalloproteinase Inhibitors; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; EC 3.4.24.24 / Matrix Metalloproteinase 2
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32. Mikou A, Al Bouzidi A, Kabbaj R, Chahdi H, Kamous W, Zoubeir Y, Rharrassi I, Rimani M, Labraimi A, El Khatib M, Rzin A, Nassih M: [Desmoplastic ameloblastoma in a 7 year old child]. Rev Laryngol Otol Rhinol (Bord); 2008;129(4-5):341-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Améoblastome desmoplastique chez un enfant de 7 ans.
  • Desmoplastic ameloblastoma is a benign, locally aggressive neoplasm of proliferating odontogenic epithelial origin.
  • A curetting of the lesion was carried out and the anatomopathologic examination retained the diagnosis of desmoplastic ameloblastoma.
  • [MeSH-major] Ameloblastoma. Jaw Neoplasms

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  • (PMID = 19408524.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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33. Tao Q, Lv B, Qiao B, Zheng CQ, Chen ZF: Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics. Oral Oncol; 2009 Dec;45(12):e239-44
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  • Ameloblastoma (AM) is recognized as a benign tumour but locally invasive with a high risk of recurrence.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology. Neoplasm Proteins / metabolism. Telomerase / metabolism
  • [MeSH-minor] Blotting, Western. Cell Culture Techniques. Cell Line, Transformed / virology. Cell Line, Tumor. Cell Proliferation. Cell Transformation, Viral. Enzyme Activation. Epigenesis, Genetic. Human papillomavirus 16. Humans. Male. Middle Aged. Reverse Transcriptase Polymerase Chain Reaction. Transfection / methods

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  • (PMID = 19833545.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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34. Wakefield MJ, Ross AH, Damato EM, Salvi SM, Baker GR: Review of lateral orbital wall ossifying fibroma. Orbit; 2010 Dec;29(6):317-20

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  • Significant histological overlap exists between fibro-osseous lesions and diagnosis is made on a clinicopathological basis.
  • Ossifying fibroma is a benign fibro-osseous neoplasm of the jaw and craniofacial complex that has generated a degree of controversy regarding diagnosis and classification, especially with respect to the psammomatoid variant.

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  • (PMID = 21158572.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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35. Shigeishi H, Yamaguchi S, Mizuta K, Nakakuki K, Fujimoto S, Amagasa T, Kamata N: Amphiregulin induces proliferative activities in osseous dysplasia. J Dent Res; 2009 Jun;88(6):563-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Human osseous dysplasia (OD) is a benign fibro-osseous neoplasm of periodontal ligament origin in which normal bone is replaced with fibrous connective tissue containing abnormal bone or cementum.
  • Therefore, we established immortalized cell lines (OD-1) from OD lesions of the jaw from an individual with gnathodiaphyseal dysplasia (GDD).

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  • (PMID = 19587163.001).
  • [ISSN] 1544-0591
  • [Journal-full-title] Journal of dental research
  • [ISO-abbreviation] J. Dent. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AREG protein, human; 0 / Amphiregulin; 0 / EGF Family of Proteins; 0 / Glycoproteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Recombinant Proteins
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36. Mendenhall WM, Werning JW, Fernandes R, Malyapa RS, Mendenhall NP: Ameloblastoma. Am J Clin Oncol; 2007 Dec;30(6):645-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma is an uncommon benign, locally aggressive odontogenic neoplasm that usually occurs in the vicinity of the mandibular molars or ramus.
  • Radiotherapy may improve the likelihood of local control in the occasional patient with incompletely resectable tumor.
  • [MeSH-major] Ameloblastoma / radiotherapy. Ameloblastoma / surgery. Jaw Neoplasms / radiotherapy. Jaw Neoplasms / surgery

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  • (PMID = 18091060.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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37. Łapienis M, Kaczmarczyk D, Zimmer-Nowicka J, Niedźwiecka I, Jesionek-Kupnicka D, Morawiec-Bajda A: [Ameloblastoma of the maxillary sinus--a case report]. Otolaryngol Pol; 2008;62(6):784-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma (adamantinoma) is a benign neoplasm deriving from the enamel organ.
  • About 20% of described cases of ameloblastoma relate to the jaw, its very rare location is gingiva or cheak tunica mucosa.

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  • (PMID = 19205533.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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38. Eckardt AM, Kokemüller H, Flemming P, Schultze A: Recurrent ameloblastoma following osseous reconstruction--a review of twenty years. J Craniomaxillofac Surg; 2009 Jan;37(1):36-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The adequate therapy of ameloblastoma may require a compromise between the least destructive treatment possible of a benign tumour and a sufficiently radical method to prevent recurrences.
  • The primary reconstruction of bones and/or soft tissues, which is likely to be performed especially for benign processes is threatened by recurrences.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Reconstructive Surgical Procedures

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  • (PMID = 19022680.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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39. Jundt G, Reichart PA: [Malignant odontogenic tumors]. Pathologe; 2008 May;29(3):205-13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • As with benign odontogenic tumors, malignant epithelial odontogenic tumors or odontogenic carcinomas are distinguished from the even rarer mesenchymal ones, the odontogenic sarcomas.
  • [MeSH-major] Jaw Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Ameloblastoma / classification. Ameloblastoma / pathology. Carcinoma / classification. Carcinoma / pathology. Carcinosarcoma / classification. Carcinosarcoma / pathology. Diagnosis, Differential. Humans. Jaw / pathology. Neoplasm Invasiveness. Sarcoma / classification. Sarcoma / pathology

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  • (PMID = 18392827.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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40. Driemel O, Berndt A, Hartmann A, Mueller-Richter UD, Bauer R, Reichert TE, Kosmehl H: [Clinical and immunohistochemical findings of intra- and extraoral angiosarcomas]. Mund Kiefer Gesichtschir; 2006 Jul;10(4):239-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: A clinico-pathologic study of typical symptoms of intra- and extraoral angiosarcomas and clinical course under therapy is presented as well as an analysis of the immunohistochemical differential diagnosis of the tumour specific formed spaces.
  • PATIENTS AND METHODS: Four male patients aged 63-78 years suffered from angiosarcomas of the maxillary sinus, the bucca (two patients) and the alveolar ridge of the lower jaw.
  • RESULTS: While the benign appearance of the lesions resulted primarily in wrong diagnoses the histopathologic examination of the biopsies revealed the characteristic pattern of angiosarcomas.
  • Wide surgical excision, radiotherapy and/or antiangiogenic chemotherapy could not prevent tumour progression and death within two and a half years after primary diagnosis.
  • ) The variable presentation and the benign appearance of oral and perioral angiosarcomas may often delay diagnosis.
  • [MeSH-major] Alveolar Process. Biomarkers, Tumor / analysis. Cheek. Hemangiosarcoma / pathology. Mandibular Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Aged. Humans. Male. Middle Aged. Neoplasm Invasiveness. Prognosis. Retrospective Studies

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  • (PMID = 16788797.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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41. DeVilliers P, Liu H, Suggs C, Simmons D, Daly B, Zhang S, Raubenheimer E, Larsson A, Wright T: Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol; 2008 Feb;32(2):256-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor.
  • Ameloblastoma is a benign, locally aggressive epithelial odontogenic tumor that has the potential to become malignant and produce metastasis to distant sites such as lungs and kidneys.
  • The histologic presentation can be, in some instances, mistaken for keratocystic odontogenic tumor (KCOT) (formerly known as odontogenic keratocyst).
  • Taken together, the results of this study strongly support calretinin as a useful immunohistochemical marker for ameloblastoma and malignant ameloblastoma and it can also be used in the differential diagnosis of KCOT.
  • [MeSH-major] Ameloblastoma / diagnosis. Biomarkers, Tumor / metabolism. Jaw Neoplasms / diagnosis. Odontogenic Cysts / diagnosis. Odontogenic Tumors / diagnosis. S100 Calcium Binding Protein G / metabolism
  • [MeSH-minor] Calbindin 2. Diagnosis, Differential. Gene Expression. Gene Expression Profiling. Humans. RNA, Messenger / metabolism. RNA, Neoplasm / analysis

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  • (PMID = 18223328.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / DE016079
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / S100 Calcium Binding Protein G
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42. Saghafi S, Zare-Mahmoodabadi R, Salehinejad J, Kadeh H, Afzal-Aghaee M: Immunohistochemical analysis of p53 and PCNA expression in calcifying odontogenic cyst. J Oral Sci; 2010 Dec;52(4):609-13
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  • Calcifying odontogenic cyst (COC) is a developmental odontogenic cyst in the jaw.
  • Because of its diverse histopathologic features and biological behavior, there has long been confusion with regard to its nature as a cyst or neoplasm.
  • This study evaluated the proliferative activity of 57 COC samples, including simple cyst (10 cases), cystic neoplasm (34 cases), solid neoplasm (6 cases) and combined lesion (7 cases) by p53 and PCNA immunohistochemical staining.
  • For assessment of p53 and PCNA positivity, the number of positively stained cells with brown-stained nuclei was counted in 1000 cells from each sample. p53 and PCNA expression in the solid neoplasm subtype were significantly higher when compared to cystic neoplasm and simple cyst (P < 0.05).
  • The results demonstrated that within benign types of COC, the amount of p53 and PCNA in proliferative epithelium is significantly higher when compared to non-proliferative epithelium. p53 and PCNA markers are possible parameters for differentiation of COC subtypes.
  • [MeSH-major] Jaw Neoplasms / metabolism. Odontogenic Cyst, Calcifying / metabolism. Proliferating Cell Nuclear Antigen / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 21206164.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Tumor Suppressor Protein p53
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43. Howell VM, Gill A, Clarkson A, Nelson AE, Dunne R, Delbridge LW, Robinson BG, Teh BT, Gimm O, Marsh DJ: Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma. J Clin Endocrinol Metab; 2009 Feb;94(2):434-41
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  • [Title] Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma.
  • CONTEXT: Parafibromin, encoded by HRPT2, is the first marker with significant benefit in the diagnosis of parathyroid carcinoma.
  • OBJECTIVE: We sought to determine the efficacy of increased expression of protein gene product 9.5 (PGP9.5), encoded by ubiquitin carboxyl-terminal esterase L1 (UCHL1) as an additional marker to loss of parafibromin immunoreactivity for the diagnosis of parathyroid carcinoma.
  • These samples included six hyperparathyroidism-jaw tumor syndrome-related tumors and 24 sporadic carcinomas.
  • PGP9.5 was positive in a tumor with the HRPT2 mutation L64P that expressed parafibromin.
  • Furthermore, UCHL1 was highly expressed in the carcinoma/hyperparathyroidism-jaw tumor syndrome group compared to normal (P < 0.05) and benign specimens (P < 0.001).
  • [MeSH-major] Carcinoma / diagnosis. Parathyroid Neoplasms / diagnosis. Tumor Suppressor Proteins / metabolism. Ubiquitin Thiolesterase / metabolism
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry / methods. Models, Biological. Mutation / physiology. Neoplasm Staging. Sensitivity and Specificity


44. Daskala I, Kalyvas D, Kolokoudias M, Vlachodimitropoulos D, Alexandridis C: Central odontogenic fibroma of the mandible: a case report. J Oral Sci; 2009 Sep;51(3):457-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Central odontogenic fibroma (COF) is a rare tumor that accounts for 0.1% of all odontogenic tumors.
  • It has been defined as a benign neoplasm, which appears in the jaw.
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Root Resorption / etiology

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  • (PMID = 19776515.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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45. Edwards PC, Fantasia JE, Saini T, Rosenberg TJ, Sachs SA, Ruggiero S: Clinically aggressive central giant cell granulomas in two patients with neurofibromatosis 1. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Dec;102(6):765-72
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  • BACKGROUND: Neurofibromatosis 1 (NF1) is an autosomal dominantly inherited disorder caused by a spectrum of mutations affecting the Nf1 gene.
  • Affected patients develop benign and malignant tumors at an increased frequency.
  • Clinical findings include multiple cutaneous café-au-lait pigmentations, neurofibromas, axillary freckling, optic gliomas, benign iris hamartomas (Lisch nodules), scoliosis, and poorly defined soft tissue lesions of the skeleton.
  • Alternatively, the CGCG in NF1 patients could represent a true neoplasm, resulting from additional, as of yet unidentified, genetic alterations to Nf1-haploinsufficient bone.
  • [MeSH-major] Granuloma, Giant Cell / complications. Jaw Diseases / complications. Neurofibromatosis 1 / complications
  • [MeSH-minor] Adult. Child. Female. Humans. Jaw / pathology. Jaw / surgery. Male. Palate, Hard / pathology. Palate, Hard / surgery. Recurrence

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  • (PMID = 17138179.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Gümgüm S, Hoşgören B: Clinical and radiologic behaviour of ameloblastoma in 4 cases. J Can Dent Assoc; 2005 Jul-Aug;71(7):481-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma is a benign but locally aggressive epithelial odontogenic neoplasm.
  • It represents 1% of all tumours of the jaw bone.

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  • (PMID = 16026635.001).
  • [ISSN] 1488-2159
  • [Journal-full-title] Journal (Canadian Dental Association)
  • [ISO-abbreviation] J Can Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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47. Cakur B, Miloglu O, Yolcu U, Göregen M, Gürsan N: Keratocystic odontogenic tumor invading the right maxillary sinus: a case report. J Oral Sci; 2008 Sep;50(3):345-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Keratocystic odontogenic tumor invading the right maxillary sinus: a case report.
  • Keratocystic odontogenic tumor (KCOT) is a benign intraosseous neoplasm of the jaw.
  • The clinical, radiological, and histological features of this tumor and its surgical management are discussed.
  • [MeSH-minor] Humans. Keratins. Male. Molar, Third. Neoplasm Invasiveness. Tomography, X-Ray Computed. Tooth, Impacted / complications. Young Adult

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  • (PMID = 18818473.001).
  • [ISSN] 1343-4934
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 68238-35-7 / Keratins
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48. Fukunaga M, Suzuki K, Saegusa N, Folpe AL: Composite hemangioendothelioma: report of 5 cases including one with associated Maffucci syndrome. Am J Surg Pathol; 2007 Oct;31(10):1567-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Composite hemangioendothelioma (HE) is a low-grade malignant vascular tumor showing varying combinations of benign, low-grade malignant, and malignant vascular components.
  • The tumors arose in the foot or lower leg in 3 patients, in the jaw in 1 patient, and as multiple tumors in the left upper extremity in 1 patient.
  • Of 4 cases with follow up (median duration, 8.6 y), 1 tumor recurred locally.
  • We conclude that composite HE should continue to be regarded as a low-grade malignant vascular tumor (HE), with significant potential for local recurrence, but little if any potential for distant metastasis.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Female. Humans. Immunoenzyme Techniques. Male. Neoplasm Recurrence, Local

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  • (PMID = 17895759.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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49. Oliveira-Neto HH, Spíndula-Filho JV, Dallara MC, Silva CM, Mendonça EF, Batista AC: Unicystic ameloblastoma in a child: a differential diagnosis from the dentigerous cyst and the inflammatory follicular cyst. J Dent Child (Chic); 2007 Sep-Dec;74(3):245-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unicystic ameloblastoma in a child: a differential diagnosis from the dentigerous cyst and the inflammatory follicular cyst.
  • Unicystic ameloblastoma (UA) is a benign epithelial odontogenic tumor of the jaws with an aggressive potential that commonly occurs in children.
  • This cystic odontogenic neoplasm is generally asymptomatic and found during routine radiographs.
  • The purposes of this report were to describe a case of UA involving the crown of the unerupted right mandibular second premolar in an 11-year-old girl under orthodontic treatment, and discuss its diagnosis and radiographic and microscopic findings, emphasizing its distinction from the dentigerous cyst and the inflammatory follicular cyst.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Cysts / pathology. Mandibular Neoplasms / pathology
  • [MeSH-minor] Bicuspid / physiopathology. Child. Dentigerous Cyst / diagnosis. Diagnosis, Differential. Female. Follicular Cyst / diagnosis. Humans. Tooth, Unerupted / etiology

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  • (PMID = 18482524.001).
  • [ISSN] 1935-5068
  • [Journal-full-title] Journal of dentistry for children (Chicago, Ill.)
  • [ISO-abbreviation] J Dent Child (Chic)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Mendes RA, Carvalho JF, van der Waal I: Biological pathways involved in the aggressive behavior of the keratocystic odontogenic tumor and possible implications for molecular oriented treatment - an overview. Oral Oncol; 2010 Jan;46(1):19-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biological pathways involved in the aggressive behavior of the keratocystic odontogenic tumor and possible implications for molecular oriented treatment - an overview.
  • In the classification of Head and Neck Tumors, published in 2005 by the World Health Organization Classification, the odontogenic keratocyst has been reclassified as a benign intraosseous neoplasm, calling it "keratocystic odontogenic tumor" (KCOT).
  • A review of the biological behavior of this recognized aggressive pathological entity of the jaws and a contemporary outline of the molecular (growth factors, p53, PCNA and Ki-67, bcl-2) and genetic (PTCH, SHH) alterations associated with this odontogenic neoplasm provides a better understanding of the mechanisms involved in its development and strengthen the current concept that the KCOT should, indeed, be regarded as a neoplasm.
  • Furthermore, markers known to be rapidly induced in response to growth factors, tumor promoters, cytokines, bacterial endotoxins, oncogenes, hormones and shear stress, such as COX-2, may also shed new light on the biological mechanisms involved in the development of these benign but sometimes aggressive neoplasms of the jaws.
  • [MeSH-major] Jaw Neoplasms. Odontogenic Cysts. Odontogenic Tumors

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  • (PMID = 20004133.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
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51. Chrcanovic BR, do Amaral MB, Marigo Hde A, Freire-Maia B: An expanded odontogenic myxoma in maxilla. Stomatologija; 2010;12(4):122-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Odontogenic myxomas are considered to be a benign odontogenic tumor with locally aggressive behavior, non-metastasizing neoplasm of the jaw bones.
  • Despite the benign nature of these lesions, there is a high rate of local recurrence after curettage alone and in certain cases requires adequate resection.
  • This paper describes a case of a large odontogenic myxoma in the maxilla, emphasizing a discussion on the differential diagnosis related to radiological findings and the surgical treatment.

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  • (PMID = 21266837.001).
  • [ISSN] 1392-8589
  • [Journal-full-title] Stomatologija
  • [ISO-abbreviation] Stomatologija
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lithuania
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52. De Corso E, Politi M, Marchese MR, Pirronti T, Ricci R, Paludetti G: Advanced giant cell reparative granuloma of the mandible: radiological features and surgical treatment. Acta Otorhinolaryngol Ital; 2006 Jun;26(3):168-72

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Giant cell reparative granuloma accounts for 1%-7% of all benign lesions of the jaw.
  • [MeSH-minor] Adult. Female. Humans. Ilium / transplantation. Neoplasm Staging

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  • (PMID = 17063987.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2639959
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