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1. Qin MJ: [Analysis of 12 puerile cases with serious cellulitis of floor of mouth]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2007 Aug;25(4):390-1
MedlinePlus Health Information. consumer health - Cellulitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of 12 puerile cases with serious cellulitis of floor of mouth].
  • OBJECTIVE: To discuss the diagnose and treatment of puerile cases with serious cellulitis of floor of mouth.
  • METHODS: The data of 12 cases with serious cellulitis of floor of mouth were retrospectively analyzed.
  • RESULTS: 12 cases with serious cellulitis of floor of mouth were all cured by systemic anti-infection and topical incision and drainage.
  • CONCLUSION: The key to treat serious cellulitis of floor of mouth is systemic anti-infection and topical incision and drainage.
  • [MeSH-major] Cellulitis. Mouth Floor

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  • (PMID = 17896500.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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2. Hamad AF, Alkureishi LW, Shoaib T: Sentinel node biopsy in floor of mouth cancers: the need to clear level I. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sentinel node biopsy in floor of mouth cancers: the need to clear level I.
  • Tumour lymphatic spread in head and neck squamous cell carcinomas is the single most important prognostic indicator.
  • We have previously highlighted the difficulties in locating sentinel nodes in the neck from floor of mouth primaries.
  • We also raised the question whether level I nodes should be cleared as part of sentinel node procedures in floor of mouth tumours.
  • We describe a case which illustrates the difficulties encountered when performing sentinel node biopsies in patients with floor of mouth cancers and the rationale behind asking such a question.

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  • (PMID = 21686503.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3029873
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3. Whitt JC, Schafer DR, Callihan MD: Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth. Head Neck Pathol; 2008 Mar;2(1):41-8
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth.
  • To have more than one tumor is unusual.
  • We report a case of an adult male who presented with a mucoepidermoid carcinoma involving the minor salivary glands of the palate at age 57 years, followed by an adenoid cystic carcinoma of the floor of mouth at age 63 years.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Mouth Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Palatal Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 20614341.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807610
  • [Keywords] NOTNLM ; Metachronous neoplasms / Multiple malignant salivary gland neoplasms / Salivary gland neoplasms / Salivary gland tumors / Synchronous neoplasms
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4. Zaleckas L, Rasteniene R, Rimkuviene J, Seselgyte R: Retrospective analysis of cellulitis of the floor of the mouth. Stomatologija; 2010;12(1):23-7
MedlinePlus Health Information. consumer health - Mouth Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retrospective analysis of cellulitis of the floor of the mouth.
  • OBJECTIVES: To analyze clinical data of patients treated for mouth floor cellulitis during 2003-2006 years at the Department of Maxillofacial Surgery, Vilnius University Hospital Zalgiris Clinic and to compare the results with existing data.
  • In 65% of cases primary diagnosis was incorrect.
  • 93.7% of mouth floor cellulites were odontogenic origin.
  • In 32.9% of the patients at the time of first examination the extension of inflammation into parapharyngeal, pterygomandibular spaces or neck together with mouth floor cellulitis was diagnosed.

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  • (PMID = 20440093.001).
  • [ISSN] 1392-8589
  • [Journal-full-title] Stomatologija
  • [ISO-abbreviation] Stomatologija
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Lithuania
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5. David D, Clayman L, Saleh H: Value of fine-needle aspiration biopsy in initial evaluation of floor of the mouth masses: report of a case of low-grade mucoepidermoid carcinoma. Diagn Cytopathol; 2010 Feb;38(2):81-4
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Value of fine-needle aspiration biopsy in initial evaluation of floor of the mouth masses: report of a case of low-grade mucoepidermoid carcinoma.
  • Low-grade mucoepidermoid carcinoma (LG MEC) is a rare tumor which can occur in the minor salivary glands as intraoral lesion, more frequently in the palate and very rarely in the floor of the mouth.
  • Traditionally, the diagnosis has been made on surgical resection specimens only.
  • In this article, we report a case of LG MEC of the floor of mouth diagnosed by FNA and confirmed by subsequent surgical resection.
  • [MeSH-major] Carcinoma, Mucoepidermoid / diagnosis. Mouth Neoplasms / diagnosis. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Middle Aged. Salivary Glands, Minor / pathology. Sialadenitis / pathology

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  • (PMID = 19688766.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Tsirevelou P, Papamanthos M, Chlopsidis P, Zourou I, Skoulakis C: Epidermoid cyst of the floor of the mouth: two case reports. Cases J; 2009;2:9360

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidermoid cyst of the floor of the mouth: two case reports.
  • INTRODUCTION: Epidermoid cysts that appear in the midline floor of the mouth are, usually, a result of entrapped ectodermal tissue of the first and second branchial arches, which fuse during the third and fourth weeks in utero.
  • The incidence in the floor of the mouth of the oral cavity is rare and development sites are the sublingual, submaxillary and submandibular spaces.
  • It was present two cases of epidermoid cyst of the floor of the mouth and discussed the different surgical approaches for this lesion.
  • CASES PRESENTATION: Two cases of midline epidermoid cysts of the floor of the mouth are presented, evaluating the different surgical approaches.
  • CONCLUSIONS: Surgery of epidermoid cyst of the floor of the mouth is the treatment of choice.

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  • (PMID = 20062607.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804007
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7. Ikeda C, Katakura A, Yamamoto N, Kamiyama I, Shibahara T, Onoda N, Tamura H: Nasolabial flap reconstruction of floor of mouth. Bull Tokyo Dent Coll; 2007 Nov;48(4):187-92
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasolabial flap reconstruction of floor of mouth.
  • The first patient was a 75-year-old man with mucoepidermoid carcinoma in the left-side floor of the mouth; requiring resection of the floor of the mouth, partial mandibulectomy, and left supraomohyoid neck dissection.
  • The second patient was a 74-year-old man with recurrent acinic cell carcinoma in the anterior oral floor infiltrating as far as the mandible.
  • After tumor resection, both cases had a nasolabial flap reconstruction.
  • [MeSH-major] Mouth Floor / surgery. Reconstructive Surgical Procedures / methods. Skin Transplantation / methods. Surgical Flaps
  • [MeSH-minor] Aged. Carcinoma, Acinar Cell / surgery. Carcinoma, Mucoepidermoid / surgery. Follow-Up Studies. Graft Survival. Humans. Male. Mandible / surgery. Mouth Neoplasms / surgery. Neck Dissection. Neoplasm Recurrence, Local / surgery

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  • (PMID = 18360105.001).
  • [ISSN] 0040-8891
  • [Journal-full-title] The Bulletin of Tokyo Dental College
  • [ISO-abbreviation] Bull. Tokyo Dent. Coll.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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8. Ko AB, Lavertu P, Rezaee RP: Double bilobed radial forearm free flap for anterior tongue and floor-of-mouth reconstruction. Ear Nose Throat J; 2010 Apr;89(4):177-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Double bilobed radial forearm free flap for anterior tongue and floor-of-mouth reconstruction.
  • We describe what is, to the best of our knowledge, the first use of a double bilobed radial forearm free flap in reconstructive surgery of the tongue and floor of the mouth following bilateral tumor resection.
  • Our patient was a 78-year-old man who had experienced tumor recurrence in the anterior floor of the mouth after previous resection and radiotherapy.
  • Although the use of a single bilobed radial forearm flap is widely used after hemiglossectomy, our double bilobed modification extends this technique to anterior tongue and floor-of-mouth defects.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Mouth Floor / surgery. Neoplasm Recurrence, Local / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue Neoplasms / surgery

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  • (PMID = 20397146.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Li JS, Pan CB, Chen WL, Wang JG, Huang HZ, Yang CH, Zhang B: [An island pectoralis major myocutaneous flap for the reconstruction of tongue and floor of mouth]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2005 Mar;21(2):112-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An island pectoralis major myocutaneous flap for the reconstruction of tongue and floor of mouth].
  • OBJECTIVE: To evaluate an island pectoralis major myocutaneous flap for immediate reconstruction of the total tongue body and the floor of the mouth after radical resection of bilateral tongue carcinoma involved.
  • METHODS: Form October 2000 to December 2002, seven patients with bilateral tongue carcinoma were selected to treat with salvage surgery, and an island pectoralis major myocutaneous flap were applied for immediate reconstruction of total body of tongue and floor of mouth.
  • The reconstructed tongue and floor of mouth worked well.
  • CONCLUSIONS: The island pectoralis major myocutaneous flap could be an ideal selection for the immediate reconstruction of the total tongue body and the floor of mouth.
  • [MeSH-major] Mouth Floor / surgery. Pectoralis Muscles / transplantation. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue / surgery

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  • (PMID = 16011197.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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10. Pino Rivero V, Pantoja Hernández CG, González Palomino A, Mora Santos ME, Barrantes Celaya G, Blasco Huelva A: [Phlegmons and abscesses in the floor of mouth. Report of 10 cases and review of the literature]. An Otorrinolaringol Ibero Am; 2006;33(6):599-606
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Phlegmons and abscesses in the floor of mouth. Report of 10 cases and review of the literature].
  • [Transliterated title] Flemones y abscesos del suelo de boca. Análisis de 10 casos y revisión de la literatura.
  • We report a review about 10 cases of phlegmons-abscesses in the floor of mouth (Ludwig's angina) treated by our Service analyzing the following variables: Age, sex, time of evolution, personal antecedents, E.N.T. exploration, clinical symptoms, type of treatment and clinical evolution.
  • This pathology represents one of the most severe forms of cervicofacial diffuse cellulitis; it requires an early diagnosis and therapy which can include an urgent tracheostomy ifthe airway is compromised.
  • [MeSH-minor] Adult. Anti-Bacterial Agents / therapeutic use. Drainage / methods. Female. Humans. Male. Middle Aged. Mouth Floor / microbiology. Retrospective Studies. Treatment Outcome

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  • (PMID = 17233275.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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11. Wu HL, Wang HM: [Sternocleidomastoid myocutaneous flap for reconstruction after resection of carcinoma in floor of mouth]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2005 Nov;34(6):574-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sternocleidomastoid myocutaneous flap for reconstruction after resection of carcinoma in floor of mouth].
  • OBJECTIVE: To evaluate the clinic outcome and indications of sternocleidomastoid (SCM) myocutaneous flap for reconstruction after resection of carcinoma in floor of mouth.
  • METHODS: Thirty-two patients underwent SCM myocutaneous flap for reconstruction of the floor of mouth were reviewed.
  • All patients had oral diet with good separation of the oral floor and the tongue, and had no difficulty in speech intelligibility.
  • CONCLUSION: The SCM myocutaneous flap appears to be easy to use and suitable for reconstruction of the defect after resection of oral floor carcinoma, the indications of this flap should be selected carefully.

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  • (PMID = 16331825.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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12. Clark JR, Franklin JH, Naranjo N, Odell MJ, Gullane PJ: Sublingual gland resection in squamous cell carcinoma of the floor of mouth: is it necessary? Laryngoscope; 2006 Mar;116(3):382-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sublingual gland resection in squamous cell carcinoma of the floor of mouth: is it necessary?
  • OBJECTIVES: Little evidence exists to guide surgeons in the management of the sublingual glands (SLG) not macroscopically involved by squamous cell carcinoma of the floor of mouth and oral tongue.
  • Clinical and pathological T stage (p = 0.023 and 0.005) and tumor thickness (p = 0.015) predicted for SLG invasion.
  • CONCLUSION: Total SLG resection in early stage and thin squamous cell carcinoma of the floor of mouth and oral tongue provides minimal oncologic benefit and is associated with increased perioperative morbidity due to neck wound complications.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Incidence. Male. Middle Aged. Mouth Floor. Neoplasm Invasiveness / pathology. Neoplasm Invasiveness / prevention & control. Neoplasm Recurrence, Local / epidemiology. Neoplasm Staging. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 16540894.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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13. Chen SL, Chen TM, Dai NT, Hsia YJ, Lin YS: Medial sural artery perforator flap for tongue and floor of mouth reconstruction. Head Neck; 2008 Mar;30(3):351-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medial sural artery perforator flap for tongue and floor of mouth reconstruction.
  • METHODS: We used 12 medial sural artery perforator flaps to reconstruct tongue and floor of mouth following cancer ablation.
  • [MeSH-major] Mouth Floor / surgery. Surgical Flaps / blood supply. Tongue / surgery

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  • [Copyright] (c) 2007 Wiley Periodicals, Inc. Head Neck, 2008.
  • (PMID = 17972307.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. MacNeil SD, Moxham JP: Review of floor of mouth dysontogenic cysts. Ann Otol Rhinol Laryngol; 2010 Mar;119(3):165-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Review of floor of mouth dysontogenic cysts.
  • OBJECTIVES: We report the common surgical approaches, incidence of sinus tracts, and recurrence rates of floor of mouth dysontogenic (epidermoid, dermoid, and teratoid) cysts in the pediatric population.
  • All English-language studies consisting of floor of mouth dysontogenic cysts were included.
  • RESULTS: There are 198 case reports, including those presented here, of floor of mouth dysontogenic cysts.
  • Most floor of mouth dysontogenic cysts can be excised by an intraoral approach.
  • There are 5 reported cases in the literature of recurrent dysontogenic cysts and 11 cases of multiple floor of mouth dysontogenic cysts.
  • CONCLUSIONS: Floor of mouth dysontogenic cysts most commonly present in the sublingual space, and most can be excised by an intraoral approach.
  • [MeSH-major] Cysts / diagnosis. Oral Surgical Procedures / methods. Teratoma / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Mouth Floor. Tomography, X-Ray Computed

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  • (PMID = 20392029.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 73
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15. Jiang YL, Li J, Sun J, Zhang FQ: [Application of palatal base combined with shield above floor of mouth for restoration of acquired mandibular defect with glossectomy: report of one case]. Shanghai Kou Qiang Yi Xue; 2010 Feb;19(1):16-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Application of palatal base combined with shield above floor of mouth for restoration of acquired mandibular defect with glossectomy: report of one case].
  • PURPOSE: To evaluate the prosthetic results of application of palatal base combined with shield above the floor of mouth for restoration of acquired mandibular defect with glossectomy.
  • Shield just above the floor of the mouth and buccal mucosa was fabricated to support the buccal mucosa and muscle.
  • CONCLUSIONS: Better prosthetic results could be obtained by using palatal base combined with shield above the floor of mouth for restoration of acquired mandibular defect with glossectomy.
  • [MeSH-major] Glossectomy. Mouth Floor
  • [MeSH-minor] Humans. Lip. Mandible. Mouth Mucosa

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  • (PMID = 20300686.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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16. Ayad T, Kolb F, De Monés E, Mamelle G, Temam S: Reconstruction of floor of mouth defects by the facial artery musculo-mucosal flap following cancer ablation. Head Neck; 2008 Apr;30(4):437-45
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reconstruction of floor of mouth defects by the facial artery musculo-mucosal flap following cancer ablation.
  • BACKGROUND: The purpose of this study is to review our experience with the use of the facial artery musculo-mucosal (FAMM) flap for floor of mouth (FOM) reconstruction following cancer ablation to assess its reliability, associated complications, and functional results.
  • METHODS: This was a retrospective analysis of 61 FAMM flaps performed for FOM reconstruction from 1997 to 2006.
  • CONCLUSION: The FAMM flap is well suited for FOM reconstruction because it is reliable, has few significant complications, and allows preservation of oral function.
  • [MeSH-major] Mouth Neoplasms / surgery. Surgical Flaps / blood supply

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  • (PMID = 17972306.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Gajewska B, Usarek E, Kaźmierczak B, Kukwa W, Kukwa A, Barańczyk-Kuźma A: [Expression of glutathione S-transferase isoenzymes in tongue and floor of mouth squamous cell carcinomas]. Pol Merkur Lekarski; 2007 Sep;23(135):196-9
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  • [Title] [Expression of glutathione S-transferase isoenzymes in tongue and floor of mouth squamous cell carcinomas].
  • It occurs in isoenzymes, expression of which changes in various pathological conditions including neoplasia.
  • The aim of the present study was to analyze the expression pattern of GST pi, mi4 and alpha in human tongue and floor of mouth squamous cell carcinomas.
  • RESULTS: Indicated statistically significant differences in GST pi mRNA expression in tumor and control tissues.
  • [MeSH-major] Carcinoma, Squamous Cell / enzymology. Glutathione Transferase / biosynthesis. Mouth Neoplasms / enzymology


18. Merkx MA, van Gulick JJ, Marres HA, Kaanders JH, Bruaset I, Verbeek A, de Wilde PC: Effectiveness of routine follow-up of patients treated for T1-2N0 oral squamous cell carcinomas of the floor of mouth and tongue. Head Neck; 2006 Jan;28(1):1-7
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  • [Title] Effectiveness of routine follow-up of patients treated for T1-2N0 oral squamous cell carcinomas of the floor of mouth and tongue.
  • The purpose of this study was to determine the benefit of our 10-year follow-up program in patients with stage I and II squamous cell carcinoma (SCC) of the floor of mouth and tongue.
  • METHODS: In a longitudinal cohort study involving 102 patients who were treated with curative intent for a pT1-2N0M0 SCC of the floor of mouth and tongue from 1989-1998 with a minimum follow-up of 5 years, we evaluated the effect of routine follow-up.
  • RESULTS: During the follow-up (mean, 61 months; SD, 4 months), 10 patients had a recurrence, and 20 patients had a second primary tumor.
  • Location, T classification of the primary tumor, choice of therapy, or measure of tumor-free margins in the resection did not significantly affect the occurrence of a secondary event (p >or= .1).
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Mouth Neoplasms / therapy. Neoplasm Recurrence, Local / therapy. Neoplasms, Second Primary / therapy
  • [MeSH-minor] Cohort Studies. Disease-Free Survival. Female. Humans. Longitudinal Studies. Male. Middle Aged. Mouth Floor. Retrospective Studies. Time Factors. Tongue Neoplasms / diagnosis. Tongue Neoplasms / therapy. Treatment Outcome

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc. Head Neck 27: XXX-XXX, 2005.
  • (PMID = 16155911.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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19. Luna-Ortiz K, Carmona-Luna T, Herrera-Gómez A, Pasche P, Jaques B: [Reconstruction of the floor of the mouth with double free flap: report of three cases]. Cir Cir; 2008 May-Jun;76(3):247-52
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  • [Title] [Reconstruction of the floor of the mouth with double free flap: report of three cases].
  • [Transliterated title] Reconstrucción con doble colgajo libre del piso anterior de la boca. Informe de tres casos.
  • BACKGROUND: We undertook this study to describe three cases of reconstruction of the floor of the mouth with two simultaneous free flaps.
  • METHODS: Three patients with cancer of the anterior floor of the mouth were subjected to segmental resection of the mandible and resection of the floor of the mouth with subsequent reconstruction using two simultaneous osseous and fasciocutaneous free flaps.
  • CONCLUSIONS: If a tumor involves osseous structures of the anterior floor of the mouth, it is best to perform surgery with wide margins with segmental resection of the mandible.
  • Surgical technique is the decision of the surgeon: how many and which types of flaps will be used for reconstruction of the anterior floor of mouth.
  • [MeSH-major] Mouth Floor / surgery. Mouth Neoplasms / surgery. Surgical Flaps

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  • (PMID = 18647559.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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20. Xie WX, Gao L, Chen MF, Feng ZK: [Malignant tumor of the floor of mouth in a patient with membranous nephrosis: Report of one case]. Shanghai Kou Qiang Yi Xue; 2009 Oct;18(5):559-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant tumor of the floor of mouth in a patient with membranous nephrosis: Report of one case].
  • The tumor-relevant antigen holds an important position in the elder's membranous nephropathy.
  • This article reported a case of malignant tumor of mouth floor complicated with membranous nephropathy, and discussed some problems that were encountered during clinical care.
  • It's believed that only radical resection of the malignant tumor of the mouth floor for this kind of patient can achieve good results from the therapy of membranous nephropathy.
  • [MeSH-major] Glomerulonephritis, Membranous. Mouth Floor. Nephrosis

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  • (PMID = 19907870.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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21. Wallwork BD, Anderson SR, Coman WB: Squamous cell carcinoma of the floor of the mouth: tumour thickness and the rate of cervical metastasis. ANZ J Surg; 2007 Sep;77(9):761-4
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  • [Title] Squamous cell carcinoma of the floor of the mouth: tumour thickness and the rate of cervical metastasis.
  • There are few studies that have examined solely carcinoma of the floor of the mouth and these studies differ in the thickness of tumour that is associated with significantly increased rates of cervical metastasis.
  • METHODS: Patients with SCC of the floor of the mouth of all stages who were treated with excision and neck dissection were identified.
  • Primary tumour thickness and other pathological features were determined in the pathological specimens and were correlated to the incidence of pathological cervical lymph node metastasis.
  • The median tumour thickness in patients with lymph node metastases (14.6 mm) differed significantly from those without metastases (8.6 mm) (P = 0.004).
  • When T1 and T2 cases were looked at in isolation, the median tumour thickness of cases with lymph node metastases (11.1 mm) again was significantly greater than those without metastases (4.6 mm) (P = 0.04).
  • There was no statistically significant association between perineural invasion or tumour differentiation and the presence of lymph node metastases.
  • CONCLUSION: Tumour thickness has been shown to be directly related to rates of cervical lymph node metastasis in floor of mouth SCC.
  • The primary tumour thickness associated with significantly increased rates of metastasis is similar to that shown in previous studies examining SCC of the oral tongue.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neck. Neoplasm Staging. Oral Surgical Procedures

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  • (PMID = 17685954.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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22. Menezes MB, Lehn CN, Gonçalves AJ: Epidemiological and histopathological data and E-cadherin-like prognostic factors in early carcinomas of the tongue and floor of mouth. Oral Oncol; 2007 Aug;43(7):656-61
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  • [Title] Epidemiological and histopathological data and E-cadherin-like prognostic factors in early carcinomas of the tongue and floor of mouth.
  • Despite recent advances in diagnosis and treatment, overall survival of people with squamous cell carcinomas of the tongue and mouth floor continues to be low.
  • We searched for epidemiological and pathological behaviors that could be involved in tumor recurrence and the influence of cellular adhesion loss in patient outcome.
  • Significant prognostic variables included age, daily alcohol intake, neural invasion and maximum tumor thickness.
  • [MeSH-major] Cadherins / metabolism. Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Age Factors. Alcohol Drinking / adverse effects. Female. Humans. Male. Mouth Floor / pathology. Mutation. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / pathology. Prognosis

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  • (PMID = 17350325.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cadherins
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23. Palmer PM, Jaffe DM, McCulloch TM, Finnegan EM, Van Daele DJ, Luschei ES: Quantitative contributions of the muscles of the tongue, floor-of-mouth, jaw, and velum to tongue-to-palate pressure generation. J Speech Lang Hear Res; 2008 Aug;51(4):828-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quantitative contributions of the muscles of the tongue, floor-of-mouth, jaw, and velum to tongue-to-palate pressure generation.
  • Activation of the floor-of-mouth, tongue, and jaw closing muscles increased tongue-to-palate pressure.
  • These findings support the use of a tongue-press exercise to strengthen floor-of-mouth muscles, tongue, and jaw-closing muscles.
  • [MeSH-major] Mandible / physiology. Mouth Floor / physiology. Muscle, Skeletal / physiology. Palate, Soft / physiology. Pressure. Tongue / physiology

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  • (PMID = 18658054.001).
  • [ISSN] 1092-4388
  • [Journal-full-title] Journal of speech, language, and hearing research : JSLHR
  • [ISO-abbreviation] J. Speech Lang. Hear. Res.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / DC 00040; United States / NIDCD NIH HHS / DC / P60-DC00976
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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24. Wein RO, Lewis AF: Synchronous reconstruction of the floor of mouth and chin with a single skin island fibular free flap. Microsurgery; 2008;28(4):223-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous reconstruction of the floor of mouth and chin with a single skin island fibular free flap.
  • RESULTS: A 70-year old male with an anterior floor of mouth squamous cell carcinoma underwent composite resection that included resection of a 5-cm ovoid component of overlying chin skin.
  • [MeSH-major] Chin / surgery. Fibula / transplantation. Mouth Floor / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps
  • [MeSH-minor] Aged. Humans. Male. Mandibular Neoplasms / secondary. Mandibular Neoplasms / surgery. Mouth Neoplasms / secondary. Mouth Neoplasms / surgery. Neoplasms, Squamous Cell / surgery. Tonsillar Neoplasms / pathology. Tonsillar Neoplasms / surgery

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  • [Copyright] (c) 2008 Wiley-Liss, Inc. Microsurgery, 2008
  • (PMID = 18335456.001).
  • [ISSN] 1098-2752
  • [Journal-full-title] Microsurgery
  • [ISO-abbreviation] Microsurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. El-Hakim IE, Alyamani A: Alternative surgical approaches for excision of dermoid cyst of the floor of mouth. Int J Oral Maxillofac Surg; 2008 May;37(5):497-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alternative surgical approaches for excision of dermoid cyst of the floor of mouth.
  • [MeSH-major] Dermoid Cyst / surgery. Mouth Floor / surgery. Mouth Neoplasms / surgery. Oral Surgical Procedures / methods

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  • (PMID = 18272345.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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26. Shi ZP, Wang CC, Lee JC, Lin YS: Post-tonsillectomy hematoma of the mouth floor. Eur Arch Otorhinolaryngol; 2006 Nov;263(11):1041-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Post-tonsillectomy hematoma of the mouth floor.
  • Hematoma of the mouth floor, an unusual complication, was reported.
  • A 21-year-old man presented with a soft, dark-red swelling of the mouth floor three days after undergoing tonsillectomy.
  • The hematoma of the mouth floor subsided spontaneously 2 weeks later.
  • The complication in this case was most likely caused by the blood vessel insult, which resulted from suspension of the mouth with tongue retraction during surgery.
  • Hematoma of the mouth floor can cause airway obstruction, and if present, health providers should be alert to the possibility of airway compromise.
  • [MeSH-major] Hematoma / etiology. Mouth Diseases / etiology. Tonsillectomy / adverse effects

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  • (PMID = 16816936.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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27. Al-Omran MK, Al-Khamis AN, Malik AK: Solitary neurofibroma of the floor of the mouth. Neurosciences (Riyadh); 2006 Jan;11(1):53-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary neurofibroma of the floor of the mouth.
  • We present a case of neurofibroma in the floor of the mouth.
  • A 74-year-old female complained of painless swelling in the right side of the floor of the mouth for 3 months.
  • Clinical examination and CT revealed a tumor involving the right side of the floor of the mouth.
  • Such a tumor arising in the area of the mouth is very rare.
  • We review the clinical and pathological features of a neurofibroma arising in the mouth.

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  • (PMID = 22266505.001).
  • [ISSN] 1319-6138
  • [Journal-full-title] Neurosciences (Riyadh, Saudi Arabia)
  • [ISO-abbreviation] Neurosciences (Riyadh)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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28. Zapater Latorre E, Jiménez Roig JP, Pérez Vallés A, Martínez Sanjuan V, Armengot Carceller M: [Cyst and pseudocyst lesions of the floor of the mouth with submental affectation]. An Otorrinolaringol Ibero Am; 2005;32(4):373-87
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  • [Title] [Cyst and pseudocyst lesions of the floor of the mouth with submental affectation].
  • [Transliterated title] Lesiones quísticas y pseudoquísticas del suelo de la boca con afectación submentoniana. Diagnóstico diferencial y tratamiento.
  • There are several lesions which can present as a cyst or pseudocyst of the floor of the mouth with submental repercussion.
  • The aim of this paper is to review the diagnosis methods which can help us to differentiate these lesions such as the surgical peculiarities of every tumour.
  • We are reporting two cases of cystic/pseudocystic lesions of the floor of the mouth with submental repercussion.
  • Ranulas, lipomas and lymphangiomas should be considered in the differential diagnosis.
  • Imaging diagnosis, fine needle aspiration and adequate treatment in all of the tumours are reviewed.
  • Differential diagnosis of cystic lesions of the floor of the mouth is important because the recommended surgery technique is not exactly the same in all of them.
  • [MeSH-major] Epidermal Cyst / diagnosis. Mouth Diseases / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Mouth Floor / pathology. Mouth Floor / surgery

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  • (PMID = 16156367.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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29. Zehlicke T, Lessle M, Gramer L: [The "ancient schwannoma". A rare tumor of the mouth floor]. HNO; 2006 Apr;54(4):307-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The "ancient schwannoma". A rare tumor of the mouth floor].
  • "Ancient schwannomas" of the mouth floor are rare, benign neoplasms derived from the nerve sheath of peripheral nerves.
  • B-scan sonography for the mouth floor and MRT imaging may be helpful in differential diagnosis.
  • Here, we report on a patient with ancient schwannoma of the floor of the mouth.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Hypoglossal Nerve Diseases / diagnosis. Mouth Floor. Mouth Neoplasms / diagnosis. Neurilemmoma / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Ki-67 Antigen / analysis. Lymph Nodes / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Prognosis. Ultrasonography

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  • (PMID = 15951994.001).
  • [ISSN] 0017-6192
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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30. Shine N, nor nurul Khasri M, Fitzgibbon J, O'Leary G: Solitary fibrous tumor of the floor of the mouth: case report and review of the literature. Ear Nose Throat J; 2006 Jul;85(7):437-9
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the floor of the mouth: case report and review of the literature.
  • Solitary fibrous tumor is an uncommon spindle cell neoplasm that is believed to be of mesenchymal origin.
  • Rarely does it originate in the oral cavity, and only 1 case of this lesion in the floor of the mouth has been previously reported.
  • We describe a new case of solitary fibrous tumor arising from the soft tissues of the floor of the mouth.
  • [MeSH-major] Fibroma / diagnosis. Mouth Neoplasms / diagnosis

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  • (PMID = 16909814.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Proto-Oncogene Proteins c-bcl-2
  • [Number-of-references] 19
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31. Akarslan ZZ, Akar V, Gültekin SE, Erten H: A fatty tissue lesion of the floor of the mouth mimicking an odontogenic lesion. Dentomaxillofac Radiol; 2008 Dec;37(8):470-3
MedlinePlus Health Information. consumer health - Mouth Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A fatty tissue lesion of the floor of the mouth mimicking an odontogenic lesion.
  • The floor of the mouth is a rare location for fatty tissue lesions.
  • In this case report, a non-capsulated lesion composed of mature adipose tissue located on the floor of the mouth causing a well-circumscribed oval radiolucent lesion close to the roots of the molar teeth due to resorption of mandible in a 33-year-old woman is reported.
  • [MeSH-major] Adipose Tissue / radiography. Connective Tissue Diseases / radiography. Mouth Diseases / radiography. Mouth Floor / radiography. Odontogenic Cysts / radiography
  • [MeSH-minor] Adult. Bone Resorption / radiography. Diagnosis, Differential. Female. Humans. Mandibular Diseases / radiography

  • MedlinePlus Health Information. consumer health - Connective Tissue Disorders.
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  • (PMID = 19033433.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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32. Morita N, Yabuta T, Todo K, Taenaka Y: A metastatic haemangiopericytoma of the floor of the mouth. Int J Oral Maxillofac Surg; 2006 Jun;35(6):563-5
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A metastatic haemangiopericytoma of the floor of the mouth.
  • A case of metastatic haemangiopericytoma in the floor of the mouth is described.
  • Haemangiopericytoma is a relatively rare slow-growing vascular tumour with variable malignant potential.
  • This tumour has been identified in almost every region of the body, but its occurrence in the oral cavity has been rarely reported.
  • The rate of regional and distant metastasis of the tumour is low.
  • [MeSH-major] Hemangiopericytoma / secondary. Mouth Floor / pathology. Mouth Neoplasms / secondary

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  • (PMID = 16472988.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Vimentin
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33. Barlow ST, Drage NA, Thomas DW: Ectopic submandibular gland presenting as a swelling in the floor of mouth. J Laryngol Otol; 2005 Nov;119(11):928-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic submandibular gland presenting as a swelling in the floor of mouth.
  • Ultrasonic and sialographic investigation showed no salivary tissue in the expected left submandibular region, but a large salivary gland in the left floor of the mouth deep to the mylohyoid muscle.
  • [MeSH-major] Choristoma / ultrasonography. Mouth Diseases / ultrasonography. Submandibular Gland
  • [MeSH-minor] Adult. Female. Humans. Mouth Floor / ultrasonography

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  • (PMID = 16354351.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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34. Puvaneswary M, Cassey J: Magnetic resonance imaging findings of a foregut duplication cyst of the floor of the mouth in a fetus. Australas Radiol; 2005 Feb;49(1):66-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnetic resonance imaging findings of a foregut duplication cyst of the floor of the mouth in a fetus.
  • The MRI findings are described in a case of foregut duplication cyst arising from the floor of the mouth in a fetus.
  • [MeSH-major] Cysts / congenital. Magnetic Resonance Imaging. Mouth Diseases / congenital. Mouth Floor / pathology
  • [MeSH-minor] Adult. Female. Humans. Pregnancy. Prenatal Diagnosis. Ultrasonography, Prenatal

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  • (PMID = 15727613.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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35. Frenken JW, Zijderveld SA, van den Bergh JP, Huisman FW, Cune MS: [Haematoma of the floor of the mouth following implant surgery]. Ned Tijdschr Tandheelkd; 2010 Jan;117(1):17-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Haematoma of the floor of the mouth following implant surgery].
  • [Transliterated title] Hematoom in de mondbodem na een implantaatbehandeling.
  • A patient experienced severe bleeding in the floor of the mouth as a consequence of the placement of 2 implants in the resorbed anterior segment of the mandible.
  • The resulting swelling of the floor of the mouth caused a life-threatening obstruction of the trachea.
  • [MeSH-minor] Humans. Intubation, Intratracheal. Male. Mandible / blood supply. Mandible / pathology. Mandible / surgery. Middle Aged. Mouth Floor / blood supply. Mouth Floor / pathology

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  • (PMID = 20180345.001).
  • [ISSN] 0028-2200
  • [Journal-full-title] Nederlands tijdschrift voor tandheelkunde
  • [ISO-abbreviation] Ned Tijdschr Tandheelkd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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36. Ramchandani PL, Sabesan T, Peters WJ, Wilson AW: Another use of the Foley catheter: retraction for operations on the floor of mouth and ventral aspect of the tongue. Br J Oral Maxillofac Surg; 2005 Feb;43(1):83-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Another use of the Foley catheter: retraction for operations on the floor of mouth and ventral aspect of the tongue.
  • A Foley catheter that is passed through the nose and sutured to the tip of the tongue can be used to facilitate retraction for operations on lesions on the ventral aspect of the tongue and the floor of the mouth.
  • [MeSH-minor] Humans. Mouth Floor / surgery. Tongue / surgery

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  • (PMID = 15620784.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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37. Mortellaro C, Dall'oca S, Greco Lucchina A, Palumbo RR, Longobardi A, Romeo A, Marenzi G, Sammartino G: Clinical difficulties in diagnosis: a rare case of lipoma of the floor of the mouth. Minerva Stomatol; 2009 Mar;58(3):107-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical difficulties in diagnosis: a rare case of lipoma of the floor of the mouth.
  • Their incidence in the floor of the mouth is very low.
  • The authors present the case of a lipoma of the floor of the mouth, the diagnosis of this lesion was challenging as many clinical signs mimicked the appearance of a common ranula.
  • Histopathologically, the lesion was classified as a lipoma, a diagnosis based on the presence of mature adipose tissue with no cytologic atypia, subdivided by rare and thin septa of fibrous tissue with the presence of few blood vessels.
  • The case reported highlights the difficulties in diagnosing lesions in the floor of the mouth and the necessity of including rare conditions like lipoma in the differential diagnosis.
  • [MeSH-major] Diagnostic Errors. Lipoma / diagnosis. Mouth Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Middle Aged. Ranula / diagnosis

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  • (PMID = 19357617.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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38. Massarelli O, Gobbi R, Raho MT, Tullio A: Three-dimensional primary reconstruction of anterior mouth floor and ventral tongue using the 'trilobed' buccinator myomucosal island flap. Int J Oral Maxillofac Surg; 2008 Oct;37(10):917-22
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Three-dimensional primary reconstruction of anterior mouth floor and ventral tongue using the 'trilobed' buccinator myomucosal island flap.
  • Three-dimensional reconstruction of the anterior mouth floor and ventral tongue after ablative surgery can be achieved using several techniques.
  • The flap provided the correct anatomical oral reconstruction for the anterior mouth floor and ventral tongue.
  • The trilobed buccinator myomucosal island flap is a suitable option for the three-dimensional reconstruction of the anterior mouth floor and ventral tongue.
  • [MeSH-major] Mouth Floor / surgery. Mouth Mucosa / transplantation. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Arteries / surgery. Carcinoma, Squamous Cell / surgery. Cheek / blood supply. Eating / physiology. Facial Muscles / blood supply. Female. Humans. Male. Mastication / physiology. Maxillary Artery / surgery. Middle Aged. Mouth Neoplasms / surgery. Neck Dissection

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  • (PMID = 18835756.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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39. Golusinski W, Waśniewska E, Jarmołowska-Jurczyszyn D, Majewski P, Golusinski P: [Histological charakteristics of tongue and floor of the mouth neoplasms and their clinical prognostic value]. Otolaryngol Pol; 2006;60(6):823-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Histological charakteristics of tongue and floor of the mouth neoplasms and their clinical prognostic value].
  • Four of them concerning tumor cell population and another four describe relation to the adjacent tissues.
  • MATERIAL AND METHODS: The material comprised tissue specimens from 80 patients with squamous cell carcinoma of the tongue and floor of the mouth who underwent the primary surgery.
  • Nevertheless statistically significant correlation between Jakobsson classification and T of the tumor, nodal metastases and local and nodal relapse has been recorded.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Mouth Floor. Mouth Neoplasms / pathology. Mouth Neoplasms / surgery. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Cohort Studies. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging / methods. Prognosis. Treatment Outcome

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  • (PMID = 17357657.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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40. El-Okeily M, El-Bouihi M, Ricard AS, Lefebvre-Majoufre C, Deminière C, Siberchicot F, Zwetyenga N: [Mouth floor and mobile tongue epidermoid carcinomas thickness: prognostic value]. Rev Stomatol Chir Maxillofac; 2008 Apr;109(2):81-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Mouth floor and mobile tongue epidermoid carcinomas thickness: prognostic value].
  • [Transliterated title] Epaisseur de l'infiltration tumorale des carcinomes épidermoïdes du plancher buccal et de la langue mobile : valeur pronostique.
  • But this classification in oral epidermoid carcinomas does not include the tumor thickness (except for T4 tumors).
  • Several studies demonstrated that tumor thickness could influence the prognosis in epidermoid carcinoma and other types of cancers.
  • The aim of our retrospective study was to assess the prognostic value of tumor thickness in oral epidermoid carcinoma.
  • PATIENTS AND METHODS: The study included patients with mouth floor or mobile tongue epidermoid carcinoma classified T1N0, T2N0 and T3N0 between 1985 and 2005.
  • A pathologist analysed the tumor thickness and cervical lymph nodes.
  • All the slides were examined to measure tumor thickness in millimetres.
  • The mean and median tumor thickness were respectively 7.7 and 6.5 mm (0.4-30).
  • The median tumor thickness was chosen for the study.
  • There was a statistically significant link between the five-year probability of global survival and the initial tumor thickness and between neck node invasion and tumor thickness (p<0.05).
  • DISCUSSION: This study suggests that tumor thickness should be taken in consideration in T1N0, T2N0 and T3N0 mouth floor and mobile tongue epidermoid carcinomas.
  • In the future, the clinical evaluation of tumor thickness will help determine the therapeutic management.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Floor / pathology. Mouth Neoplasms / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Lymph Nodes / pathology. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 18328517.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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41. Hu YJ, Su T, Qu XZ, Liu L, Fu JY, Zhang CP: [Application of individualized free anterolateral thigh combined flap for tongue and mouth floor defects resulted from tongue carcinoma]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2009 Sep;25(5):332-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Application of individualized free anterolateral thigh combined flap for tongue and mouth floor defects resulted from tongue carcinoma].
  • OBJECTIVE: To investigate the application of individualized free anterolateral thigh combined flap (ALTCF) for tongue and mouth floor defect resulted from tongue carcinoma.
  • METHODS: From 2006 to 2008, individualized ALTCFs were used in 31 cases of tongue and mouth floor defects resulted from tongue carcinoma.
  • CONCLUSIONS: Individualized ALTCF is a reliable flap for the tongue and month floor defects resulted from tongue carcinoma.
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Mouth Floor / pathology. Reconstructive Surgical Procedures / methods

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  • (PMID = 20030107.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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42. Breugem CC, Olesen PR, Fitzpatrick DG, Courtemanche DJ: Subperiosteal release of the floor of the mouth in airway management in Pierre Robin sequence. J Craniofac Surg; 2008 May;19(3):609-15
MedlinePlus Health Information. consumer health - Choking.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subperiosteal release of the floor of the mouth in airway management in Pierre Robin sequence.
  • We performed a retrospective study to determine the usefulness of subperiosteal release of the floor of the mouth in PRS with airway problems.
  • Between 1991 and 2005, 14 consecutive patients with PRS were treated with subperiosteal release of the floor of the mouth performed at the British Columbia's Children's Hospital.
  • If conservative measures fail to relieve supraglottic airway obstruction seen in patients with PRS, a subperiosteal release of the floor of the mouth can be an effective intervention in certain patients.
  • [MeSH-major] Airway Obstruction / surgery. Mouth Floor / surgery. Oral Surgical Procedures / methods. Pierre Robin Syndrome / surgery

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  • (PMID = 18520372.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Chimona TS, Papadakis CE, Hatzidakis AA, Velegrakis GA: Arteriovenous malformation of the floor of the mouth: a case report. Eur Arch Otorhinolaryngol; 2005 Nov;262(11):939-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Arteriovenous malformation of the floor of the mouth: a case report.
  • The case of a patient with an arteriovenous malformation of the floor of the mouth diagnosed late in her adulthood and its management are presented.
  • [MeSH-major] Arteriovenous Malformations / pathology. Mouth Floor / blood supply

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  • [Cites] AJR Am J Roentgenol. 1991 Sep;157(3):559-64 [1872245.001]
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  • (PMID = 15895290.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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44. Del Castillo-Pardo de Vera JL, López-Arcas Calleja JM, Burgueño-García M: Hematoma of the floor of the mouth and airway obstruction during mandibular dental implant placement: a case report. Oral Maxillofac Surg; 2008 Dec;12(4):223-6
MedlinePlus Health Information. consumer health - Choking.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hematoma of the floor of the mouth and airway obstruction during mandibular dental implant placement: a case report.
  • BACKGROUND: Hematoma of the floor of the mouth during mandibular dental implant placement is a rare but potentially life-threatening complication.
  • REPORT: A 53-year-old man developed a hematoma of the floor of the mouth following a dental implant procedure, requiring admission to the hospital.
  • SUMMARY: The floor of the mouth is richly vascularized by a number of branches of the submental and sublingual arteries.
  • During a dental implant procedure in the anterior zone of the mandible, perforation of the lingual cortex may invade the floor of the mouth and therefore damage structures within the sublingual space.
  • [MeSH-major] Airway Obstruction / etiology. Dental Implantation, Endosseous / adverse effects. Hematoma / etiology. Mouth Floor / injuries. Oral Hemorrhage / etiology

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  • (PMID = 18825423.001).
  • [ISSN] 1865-1550
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


45. Ricard AS, Rivel J, Demeaux H, Majoufre-Lefebvre C, Siberchicot F, Zwetyenga N: [Prognostic value of infiltration of squamous cell carcinoma of the floor of the mouth]. Ann Otolaryngol Chir Cervicofac; 2008 Jun;125(3):134-8
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognostic value of infiltration of squamous cell carcinoma of the floor of the mouth].
  • [Transliterated title] Valeur pronostique de l'infiltration des carcinomes épidermoïdes du plancher buccal.
  • OBJECTIVE: The aim of this preliminary retrospective study was to evaluate the prognostic value of tumor thickness in squamous cell carcinoma of the floor of the mouth.
  • MATERIALS AND METHODS: A total of 61 patients with previously untreated T1N0, T2N0 or T3N0 squamous cell carcinoma of the floor of the mouth were included in this preliminary study.
  • An optical micrometer was used to determine the maximum of tumor thickness.
  • We studied the relation between the overall survival at two and five years and tumor thickness.
  • CONCLUSION: The prognostic value of tumor thickness was not demonstrated in this preliminary study.
  • We are currently conducting a study involving a larger patient population in our unit and we believe that tumor thickness should be considered in the management plan for patients with oral carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Floor / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Prognosis

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  • (PMID = 18539260.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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46. Fillies T, Buerger H, Gaertner C, August C, Brandt B, Joos U, Werkmeister R: Catenin expression in T1/2 carcinomas of the floor of the mouth. Int J Oral Maxillofac Surg; 2005 Dec;34(8):907-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Catenin expression in T1/2 carcinomas of the floor of the mouth.
  • Eighty-five patients with histologically proven T1/2 squamous cell carcinoma of the oral floor who underwent surgical treatment were eligible for the study.
  • Loss of alpha-catenin expression in carcinoma of the floor of the mouth correlated significantly with poor prognosis (P=0.05).
  • Catenin expression in carcinomas of the floor of the mouth seems to be a predictive parameter in the prognosis of T1 and T2 SSCs.
  • [MeSH-major] Biomarkers, Tumor / biosynthesis. Carcinoma, Squamous Cell / metabolism. Catenins / biosynthesis. Mouth Floor / pathology. Mouth Neoplasms / metabolism

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  • (PMID = 15916880.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Catenins
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47. Gadre S, Ryan MW, Logroño R: MALT lymphoma of the floor of the mouth: a case report. Ear Nose Throat J; 2009 Aug;88(8):E1-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MALT lymphoma of the floor of the mouth: a case report.
  • Here we report a case of a MALT lymphoma of the floor of the mouth that likely arose in the sublingual gland.
  • [MeSH-major] Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / radiotherapy. Mouth Neoplasms / diagnosis. Mouth Neoplasms / radiotherapy. Tomography, X-Ray Computed
  • [MeSH-minor] Biomarkers / metabolism. Biopsy. Female. Flow Cytometry. Follow-Up Studies. Humans. Middle Aged. Mouth Floor. Neoplasm Staging. Staining and Labeling. Sublingual Gland. Treatment Outcome

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  • (PMID = 19688701.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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48. Simonato LE, Garcia JF, Sundefeld ML, Mattar NJ, Veronese LA, Miyahara GI: Detection of HPV in mouth floor squamous cell carcinoma and its correlation with clinicopathologic variables, risk factors and survival. J Oral Pathol Med; 2008 Nov;37(10):593-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection of HPV in mouth floor squamous cell carcinoma and its correlation with clinicopathologic variables, risk factors and survival.
  • The purpose of this study was to investigate the prevalence of HPV in mouth floor squamous cell carcinoma and correlate it with clinicopathologic variables, risk factors and survival.
  • HPV presence was evaluated by nested polymerase chain reaction (nPCR) in 29 paraffin-embedded specimens of mouth floor squamous cell carcinoma.
  • The relatively low incidence of HPV DNA present in these tumors suggests that this virus does not, by itself, have a significant role in the development of mouth floor squamous cell carcinoma.
  • [MeSH-major] Alphapapillomavirus / isolation & purification. Carcinoma, Squamous Cell / virology. Mouth Floor / virology. Mouth Neoplasms / virology
  • [MeSH-minor] DNA, Viral / analysis. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Staging. Papillomavirus Infections / virology. Polymerase Chain Reaction / methods. Retrospective Studies. Risk Factors

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  • (PMID = 19012621.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Viral
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49. Clark S, Greenwood M, Fullarton M, Russell JS: An unusual case of floor of mouth swelling: case report, differential diagnosis and a review of the literature. Dent Update; 2005 Dec;32(10):617-9
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  • [Title] An unusual case of floor of mouth swelling: case report, differential diagnosis and a review of the literature.
  • A case of an intra-oral spindle cell lipoma in a 55-year-old female is reported, a differential diagnosis is presented and the histopathology is discussed.
  • [MeSH-major] Lipoma / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Diagnosis, Differential. Female. Humans. Middle Aged. Mouth Floor / pathology. Ranula / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 16379439.001).
  • [ISSN] 0305-5000
  • [Journal-full-title] Dental update
  • [ISO-abbreviation] Dent Update
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 11
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50. Alsharif MJ, Zhao Y: Teratoid cyst of floor of the mouth: a clinicopathologic study of 20 Chinese patients. Int J Surg Pathol; 2009 Apr;17(2):111-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Teratoid cyst of floor of the mouth: a clinicopathologic study of 20 Chinese patients.
  • The aim of this study is to document the clinicopathologic features of teratoid cyst of the floor of the mouth in 20 Chinese patients, who were treated in Wuhan University.
  • The age at diagnosis ranged from 25 days to 34 years, and the greatest frequency was within the first decade.
  • [MeSH-major] Mouth Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18480388.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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51. Aarts MC, Hogen Esch TT, Terhaard CH, Koole R, Hordijk GJ: Guidelines in head and neck oncology compliance and consequences of deviations from the standard protocol for tongue and floor of mouth squamous carcinoma. Clin Otolaryngol; 2005 Oct;30(5):444-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Guidelines in head and neck oncology compliance and consequences of deviations from the standard protocol for tongue and floor of mouth squamous carcinoma.
  • OBJECTIVES: To investigate the extent of violation of a regional guideline for the treatment of patients with carcinoma of the tongue/floor of mouth (ICD0 C02, C04).
  • PARTICIPANTS: A total of 217 patients treated between 1991 and 2001 for a stage II and stage III carcinoma of the tongue/floor of mouth.
  • MAIN OUTCOME MEASURES: Protocol violation, tumour recurrence.
  • There was no statistically significant difference in tumour recurrence between the two groups for stage II (P=0.68) or stage III (P=0.97) disease, or between undertreatment and overtreatment of patients with stage II (P=0.47) or stage III (P=0.90) disease.
  • CONCLUSIONS: Although protocol violation occurs in as many as 45% of patients, this does not result in a worse tumour recurrence.
  • Neither overtreatment nor undertreatment appears to affect the overall tumour recurrence.
  • [MeSH-major] Mouth Neoplasms / therapy. Tongue Neoplasms / therapy
  • [MeSH-minor] Female. Humans. Male. Middle Aged. Mouth Floor. Practice Guidelines as Topic. Retrospective Studies. Treatment Outcome

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  • (PMID = 16232249.001).
  • [ISSN] 1749-4478
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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52. Calabrese L, Garusi C, Giugliano G, Ansarin M, Bruschini R, Chiesa F: Composite reconstruction in advanced cancer of the mouth floor: autogenous frozen-thawed mandibular bone and free flaps. Microsurgery; 2007;27(1):21-6
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  • [Title] Composite reconstruction in advanced cancer of the mouth floor: autogenous frozen-thawed mandibular bone and free flaps.
  • Seven patients with advanced squamous cell carcinoma of the floor of the mouth underwent block resection with immediate reconstruction, using the removed mandible treated with liquid nitrogen and covered with a free forearm flap.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Glossectomy. Mandible / surgery. Mouth Neoplasms / surgery. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Adult. Aged. Dissection. Female. Humans. Lymph Node Excision. Male. Middle Aged. Mouth Floor. Pilot Projects. Reconstructive Surgical Procedures. Surgical Flaps

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17205573.001).
  • [ISSN] 0738-1085
  • [Journal-full-title] Microsurgery
  • [ISO-abbreviation] Microsurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Weijers M, Snow GB, Bezemer PD, van der Waal I: Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients. J Oral Pathol Med; 2009 Apr;38(4):343-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients.
  • In a retrospective study on 128 previously untreated patients with a T1 or T2 squamous cell carcinoma of the tongue and the floor of the mouth, the value of the classical Broders' grading system and the malignancy grading system were compared with regard to various outcome measures such as regional metastasis, local recurrence and 5-year survival.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Male. Middle Aged. Mouth Floor / pathology. Neoplasm Metastasis. Neoplasm Recurrence, Local. Neoplasms, Second Primary. Prognosis. Retrospective Studies. Tongue Neoplasms / classification. Tongue Neoplasms / pathology

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  • (PMID = 19222711.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Denmark
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54. Coimbra F, Lopes JM, Figueiral H, Scully C: Spindle cell lipoma of the floor of the mouth. A case report. Med Oral Patol Oral Cir Bucal; 2006 Aug;11(5):E401-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spindle cell lipoma of the floor of the mouth. A case report.
  • A sessile swelling in the floor of the mouth appeared three years ago in a 29-year old Caucasian female located laterally to the opening of the right duct of Wharton.
  • After excision, histological examination revealed the presence of a tumor formed by areas of mature adipose cells interspersed with extensions of tightly disposed fusiform fibroblasts immunoreactive for vimentin and CD-34.
  • These features led to the diagnosis of a spindle cell lipoma with chondrous metaplasia.
  • The relative rarity of such a tumor in this location, especially in the chondrous variety, was considered worth of presentation, while the differential diagnosis with other intraoral tumors, namely mucoceles, dermoid cysts, mesenchymomas, fibromas and myxomas of the floor of the mouth, is discussed.
  • [MeSH-major] Lipoma / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Mouth Floor / pathology

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  • (PMID = 16878055.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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55. Svetitskiĭ PV, Islamova EF: [About surgical treatment of mucous membrane of mouth floor and tongue cancer]. Stomatologiia (Mosk); 2005;84(5):55-7
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  • [Title] [About surgical treatment of mucous membrane of mouth floor and tongue cancer].
  • In the department of head and neck tumors of Rostov Research Oncological Institute the operation on advanced mouth floor and tongue cancer is proposed comprising removement of the regional lymph nodes and resection of the tongue and mouth floor.
  • [MeSH-major] Glossectomy / methods. Mouth Floor / surgery. Mouth Neoplasms / surgery. Tongue Neoplasms / surgery
  • [MeSH-minor] Disease-Free Survival. Follow-Up Studies. Humans. Mouth Mucosa / pathology. Mouth Mucosa / surgery. Retrospective Studies. Treatment Outcome

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  • (PMID = 16247395.001).
  • [ISSN] 0039-1735
  • [Journal-full-title] Stomatologii︠a︡
  • [ISO-abbreviation] Stomatologiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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56. Kokong DD, Ibekwe TS, Okolo CA, Kodiya AM, Fasunla JA, Nwaorgu OG, Akang EE: Amyloid angiopathy of the floor of the mouth: a case report and review of the literature. J Med Case Rep; 2007;1:117

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  • [Title] Amyloid angiopathy of the floor of the mouth: a case report and review of the literature.
  • Diagnosis has remained mostly at autopsy.A case of amyloid angiopathy involving the submandibular gland and floor of the mouth with an associated fatal bleed is reported.

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  • [Cites] Mt Sinai J Med. 1996 Jan;63(1):16-23 [8935845.001]
  • [Cites] N Engl J Med. 1997 Sep 25;337(13):898-909 [9302305.001]
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  • (PMID = 17967184.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2147018
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57. Umeda M, Minamikawa T, Shigeta T, Oguni A, Kataoka T, Takahashi H, Shibuya Y, Komori T: Metastasis to the lingual lymph node in patients with squamous cell carcinoma of the floor of the mouth: a report of two cases. Kobe J Med Sci; 2009;55(3):E67-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis to the lingual lymph node in patients with squamous cell carcinoma of the floor of the mouth: a report of two cases.
  • Cancer of the tongue or the floor of the mouth sometimes metastasizes to the lingual lymph node.
  • We present two patients with squamous cell carcinoma of the floor of the mouth who developed metastases to the lateral lingual lymph nodes.
  • Case 1, a 62-year old male, had squamous cell carcinoma of the floor of the mouth (T3N2cM0).
  • He underwent tumor resection and bilateral neck dissection, and histological examination revealed five metastatic nodes including the lateral lingual node near the hyoid bone.
  • Case 2, a 62-year old male, had squamous cell carcinoma of the floor of the mouth (T2N2cM0).
  • He underwent tumor resection and bilateral neck dissection, and histological examination revealed three metastatic nodes including the lateral lingual node near the sublingual gland.
  • Metastasis to the lingual lymph node may cause a recurrence of oral cancer in the neck, since conventional neck dissection cannot remove this node even in the case of en bloc resection of the primary tumor and the neck.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Lymphatic Metastasis / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Humans. Lymph Nodes / pathology. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neoplasm Metastasis. Palpation. Tomography, X-Ray Computed

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  • (PMID = 20847593.001).
  • [ISSN] 1883-0498
  • [Journal-full-title] The Kobe journal of medical sciences
  • [ISO-abbreviation] Kobe J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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58. Suzuki H, Matsuura K, Hiraki N, Kadokawa Y, Hashida K, Udaka T, Nagatani G: Digastric muscle sew-up procedure for the repair of the floor of the mouth following pull-through operation for oral cancers. Ann Otol Rhinol Laryngol; 2008 Oct;117(10):745-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Digastric muscle sew-up procedure for the repair of the floor of the mouth following pull-through operation for oral cancers.
  • OBJECTIVES: We report the digastric muscle sew-up procedure for the repair of the floor of the mouth following the pull-through operation for advanced oral cancers.
  • METHODS: Eleven patients with advanced oral cancers (of the tongue in 8 cases and of the floor of the mouth in 3 cases) were retrospectively analyzed.
  • One-third glossectomy and hemiglossectomy were performed in 4 patients each; the other 3 patients underwent tumor resection on the floor of the mouth.
  • After neck dissection and tumor resection via the pull-through approach, the floor of the mouth was repaired simply by sewing the digastric muscle to the mandibular base.
  • The surfaces of the transected musculature of the tongue and the floor of the mouth were left uncovered and exposed to the oral cavity.
  • Neck infection or the formation of a fistula on the floor of the mouth was not seen.
  • CONCLUSIONS: We believe that the digastric muscle sew-up procedure is a simple, safe, and timesaving method for the repair of small to medium-sized defects of the floor of the mouth created by ablative surgery in patients with advanced oral cancers.
  • [MeSH-major] Mouth Floor / surgery. Mouth Neoplasms / surgery. Muscle, Skeletal / surgery. Oral Surgical Procedures / methods. Reconstructive Surgical Procedures / methods. Suture Techniques

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  • (PMID = 18998502.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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59. Reychler H, Mahy P: [Cancer of the floor of the mouth in a ninety-four year old female patient: a record and its justification]. Rev Stomatol Chir Maxillofac; 2007 Apr;108(2):143-5
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  • [Title] [Cancer of the floor of the mouth in a ninety-four year old female patient: a record and its justification].
  • [Transliterated title] Cancer du plancher oral chez une nonagénaire: un record et sa justification.
  • OBSERVATION: A 94-year old female patient, with a squamous cell carcinoma of the floor of the mouth, stage pT1pN0cM0, was classically treated by surgical tumor resection, selective neck dissection and immediate surgical reconstruction with a vascularized radial flap.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Floor / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Female. Humans. Neck Dissection. Neoplasm Staging. Surgical Flaps

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  • (PMID = 17275052.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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60. Song XM, Ye JH, Yuan Y, Zhang SY, Jiang HB, Wu YN: Radial forearm free flap for reconstruction of a large defect after radical ablation of carcinoma of the tongue and floor of the mouth: some new modifications. ORL J Otorhinolaryngol Relat Spec; 2010;72(2):106-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radial forearm free flap for reconstruction of a large defect after radical ablation of carcinoma of the tongue and floor of the mouth: some new modifications.
  • METHODS: Between 2003 and 2007, 15 patients with infiltrating squamous cell carcinoma (T(3)-T(4)) of the tongue and/or floor of the mouth underwent hemiglossectomy and resection of the floor of the mouth with microvascular reconstruction using a modified radial forearm flap.
  • The mean size of the forearm flap was 7.5 x 14 cm, and the de-epithelialized area was 7 x 6 cm, requiring no skin graft from the abdomen.
  • CONCLUSIONS: The modified flap used for reconstructing large defects of the tongue and floor of the mouth might be a valid substitute for pectoralis major myocutaneous flap to improve the outcome in individuals with significant oral carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Glossectomy / methods. Mouth Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue Neoplasms / surgery

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20453547.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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61. Hitter A, Soriano E, Bettega G, Karkas A, Reyt E, Righini CA: [Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation of oncological control and treatment related morbidity]. Rev Laryngol Otol Rhinol (Bord); 2007;128(3):155-62
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  • [Title] [Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation of oncological control and treatment related morbidity].
  • [Transliterated title] Traitement par chirurgie et radiothérapie des carcinomes epidermoïdes T3-T4 du plancher buccal: résultats carcinologiques et etude de la morbidité liée au traitement.
  • OBJECTIVE: The aims of this study were to evaluate the therapeutic outcome and morbidity associated with management of squamous cell carcinoma (SCC) T3-T4 of the floor of the mouth.
  • 1) Presence of a locally advanced (T3-T4) lesion of the floor of the mouth;.
  • 3) No previous treatment of the floor of the mouth;.
  • The majority of patients (93.6%) presented with a stage IVa tumour and no clinical evidence of cervical lymphadenopathy in 60% of cases.
  • CONCLUSION: T3-T4 tumours of the floor of the mouth are managed by surgical resection and adjuvant radiotherapy.
  • The prognosis of locally advanced tumours of the floor of the mouth remains humble.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Mouth Floor / surgery. Mouth Neoplasms / surgery
  • [MeSH-minor] Adult. Age Factors. Aged. Bone Transplantation. Disease-Free Survival. Female. Follow-Up Studies. Hospitalization. Humans. Male. Mandible / surgery. Middle Aged. Neck Dissection. Neoplasm Recurrence, Local / prevention & control. Neoplasm Staging. Postoperative Complications. Radiotherapy, Adjuvant. Reconstructive Surgical Procedures / methods. Retrospective Studies. Surgical Flaps. Survival Rate. Treatment Outcome

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  • (PMID = 18323327.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] France
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62. Nishioka S, Nishioka T: Carcinoma of the floor of the mouth: a case treated with precisely controlled external beam radiotherapy. Jpn J Clin Oncol; 2007 Jan;37(1):62-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoma of the floor of the mouth: a case treated with precisely controlled external beam radiotherapy.
  • A new external radiotherapy system has been developed for head and neck cancer and a case with T2 oral floor carcinoma treated with this system is presented in this report.
  • The system consists of real-time tumor-tracking equipment and a gold-marker implanted mouthpiece.
  • A confluent fibrinous mucositis developed in the oral floor mucosa that corresponded to 90% dose area.
  • The patient is currently free from both tumor and complication during a follow-up period of 48 months.
  • External radiotherapy can be an option as a curative treatment for early stage carcinoma of the floor of the mouth provided that patient set-up is rigid and reproducible.
  • [MeSH-major] Mouth Neoplasms / radiotherapy

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  • (PMID = 17095523.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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63. Pal K, Abdulla AM: Congenital imperforate submandibular duct in a newborn. Indian J Pediatr; 2007 Jul;74(7):687-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Varried conditions such as ranula, epidermal/dermal inclusion cyst, lymphatic cyst, thyroglossal cyst, sialolithiasis, branchial cleft cyst are known to produce swelling in the floor of mouth.
  • Rarely imperforate or duplication anomaly of submandiblar duct may produce cystic lesion in the floor of mouth.
  • [MeSH-minor] Cysts / congenital. Cysts / diagnosis. Diagnosis, Differential. Humans. Infant, Newborn. Male

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  • [Cites] Br J Oral Maxillofac Surg. 2001 Dec;39(6):480-2 [11735147.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1992 Sep;24(2):161-9 [1428595.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1984 Dec;58(6):656-8 [6594655.001]
  • (PMID = 17699979.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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64. Moergel M, Jahn-Eimermacher A, Krummenauer F, Reichert TE, Wagner W, Wendt TG, Werner JA, Al-Nawas B: Effectiveness of adjuvant radiotherapy in patients with oropharyngeal and floor of mouth squamous cell carcinoma and concomitant histological verification of singular ipsilateral cervical lymph node metastasis (pN1-state)--a prospective multicenter randomized controlled clinical trial using a comprehensive cohort design. Trials; 2009 Dec 23;10:118
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effectiveness of adjuvant radiotherapy in patients with oropharyngeal and floor of mouth squamous cell carcinoma and concomitant histological verification of singular ipsilateral cervical lymph node metastasis (pN1-state)--a prospective multicenter randomized controlled clinical trial using a comprehensive cohort design.
  • However, no clinical studies have been published addressing the effectiveness of postoperative radiotherapy in patients with small tumor (pT1, pT2) and concomitant ipsilateral metastasis of a single lymph node (pN1), which would provide a basis for a general treatment recommendation.
  • Since patients with small tumor (T1/T2) but singular lymph node metastasis are rare and the amount of patients consenting to randomization is not predictable in advance, all patients rejecting randomization will be treated as preferred and enrolled in a prospective observational study (comprehensive cohort design) after giving informed consent.
  • Secondary clinical endpoints are as follows: incidence and time to tumor relapse (locoregional relapse, lymph node involvement and distant metastatic spread), Quality of life as reported by EORTC (QLQ-C30 with H&N 35 module), and time from operation to orofacial rehabilitation.

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  • [Cites] J Craniomaxillofac Surg. 1999 Oct;27(5):275-88 [10717829.001]
  • [Cites] Ann Surg. 2008 Aug;248(2):180-8 [18650626.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2002 Jul;128(7):751-8 [12117328.001]
  • [Cites] N Engl J Med. 2004 May 6;350(19):1937-44 [15128893.001]
  • [Cites] Head Neck Surg. 1984 Jan-Feb;6(3):724-9 [6693288.001]
  • [Cites] Int J Oral Maxillofac Surg. 1994 Jun;23(3):140-8 [7930766.001]
  • [Cites] Surgery. 1995 Sep;118(3):459-67 [7652679.001]
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  • (PMID = 20028566.001).
  • [ISSN] 1745-6215
  • [Journal-full-title] Trials
  • [ISO-abbreviation] Trials
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00964977
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804680
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65. Broćić M, Kozomara R, Cerović S, Jović N, Vukelić-Marković S, Stosić S: Clinical significance of vascular endothelial growth factor expression in patients with carcinoma of the mouth floor and tongue. Vojnosanit Pregl; 2009 Jun;66(6):440-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical significance of vascular endothelial growth factor expression in patients with carcinoma of the mouth floor and tongue.
  • Angiogenesis is a cascade-like mechanism which is essential for tumor growth and metastasis.
  • METHODS: This retrospective study analysed 40 patients who had been operated for OSCC of their tongue and the mouth floor.
  • The value of VEGF expression of 20% was rated as significant expression, whereas tumor cells reactivation less than 20% was considered very low or no expression at all.
  • No statistical correlation was found between the level of VEGF expression and histological and nuclear grade, tumor size, disease relapse or patients overall survival.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Mouth Neoplasms / metabolism. Tongue Neoplasms / metabolism. Vascular Endothelial Growth Factor A / metabolism
  • [MeSH-minor] Adult. Aged. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Mouth Floor. Neoplasm Recurrence, Local. Prognosis

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  • (PMID = 19583141.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Serbia
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A
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66. Kawano K, Yanagisawa S: Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth. Head Neck; 2006 Jun;28(6):525-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth.
  • BACKGROUND: Laminin-5 (Ln-5) cleaved by membrane type 1-matrix metalloproteinase (MT1-MMP) enhances the migration of tumor cells.
  • The purpose of this study was to determine whether or not enhanced expression of both Ln-5 and MT1-MMP was associated with lymph node metastasis in patients with T1 and T2 squamous cell carcinoma (SCC) of the tongue and floor of the mouth.
  • Multivariate analysis identified tumor thickness (odds ratio, 4.751; p = .0152) and Ln-5/ MT1-MMP expression (odds ratio, 3.795, p = .0304) as independent factors of node metastasis.
  • CONCLUSION: These results suggest that immunohistochemical evaluation of Ln-5 and MT1-MMP expression is useful for identifying patients with T1 and T2 SCC of the tongue and floor of the mouth who should be treated with elective neck dissection.

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  • (PMID = 16619276.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Adhesion Molecules; 0 / kalinin; EC 3.4.24.80 / Matrix Metalloproteinase 14
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67. Ikeda K, Koseki T, Maehara M, Ohmura N, Kurokawa H, Shimizutani K, Sawada S: Hourglass-shaped sublingual dermoid cyst: MRI features. Radiat Med; 2007 Jul;25(6):306-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dermoid cysts located in the floor of the mouth are classified as submental or sublingual based on their location with respect to the mylohyoid muscle.
  • An hourglass-shaped cyst of the floor of mouth was seen.
  • [MeSH-major] Dermoid Cyst / diagnosis. Magnetic Resonance Imaging. Mouth Floor. Mouth Neoplasms / diagnosis

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  • [Cites] AJR Am J Roentgenol. 1983 Dec;141(6):1239-40 [6606323.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1955 Nov;8(11):1149-64 [13266349.001]
  • [Cites] J Oral Maxillofac Surg. 1993 Jul;51(7):790-2 [8509922.001]
  • [Cites] Dentomaxillofac Radiol. 1992 May;21(2):102-4 [1397456.001]
  • [Cites] AJR Am J Roentgenol. 1993 Jul;161(1):183-6 [8517299.001]
  • [Cites] Radiology. 1987 Apr;163(1):211-6 [3823437.001]
  • [Cites] J Laryngol Otol. 1997 Dec;111(12):1179-82 [9509113.001]
  • (PMID = 17634886.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


68. Henson B, Li F, Coatney DD, Carey TE, Mitra RS, Kirkwood KL, D'Silva NJ: An orthotopic floor-of-mouth model for locoregional growth and spread of human squamous cell carcinoma. J Oral Pathol Med; 2007 Jul;36(6):363-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An orthotopic floor-of-mouth model for locoregional growth and spread of human squamous cell carcinoma.
  • Floor-of-the-mouth murine models have been developed to study tumor growth, invasion, and metastasis of murine squamous cell carcinoma (SCC) cells in immunocompetent mice and invasion and metastasis of human SCC cells in nude mice.
  • However, there are tumor cell lines that do not produce tumors in mice, using standard techniques, thus reducing the utility of the model to study specific genetic or treatment conditions.
  • Furthermore, these techniques require large tumor volumes raising the possibility of airway compromise.
  • In this report, we detail significant modifications to the orthotopic floor-of-mouth murine model for human SCC to facilitate predictable growth of a large panel of University of Michigan SCC cell lines.
  • Furthermore, we describe the use of bioluminescence and micro-computed tomography to monitor tumor growth and bony invasion.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Disease Models, Animal. Mouth Neoplasms / pathology
  • [MeSH-minor] Animals. Cattle. Cell Line, Tumor. Collagen. Drug Combinations. Humans. Laminin. Luminescent Measurements. Maxilla / pathology. Maxilla / radiography. Mice. Mice, Nude. Microcomputers. Mouth Floor / pathology. Mouth Floor / radiography. Neoplasm Invasiveness. Proteoglycans. RANK Ligand / genetics. Tomography, X-Ray Computed / methods. Transplantation, Heterologous. Tumor Burden

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  • (PMID = 17559499.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Laminin; 0 / Proteoglycans; 0 / RANK Ligand; 119978-18-6 / matrigel; 9007-34-5 / Collagen
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69. Pathak KA, Shah BC: Marginal mandibulectomy: 11 years of institutional experience. J Oral Maxillofac Surg; 2009 May;67(5):962-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Literature on marginal mandibulectomy deals mainly with floor of mouth cancers.
  • The purpose of the present study was to evaluate the oncologic outcome of marginal mandibulectomy in buccal sulcus cancer as compared with floor of mouth cancer.
  • Oncologic outcomes in terms of disease control and cause-specific survival for the gingival buccal and tongue/floor of mouth cancers were compared.
  • RESULTS: A total of 137 marginal mandibulectomies were done for SCC in gingival buccal complex and 24 for floor of mouth SCC.
  • Bone was microscopically involved in 13 (8.1%) cases and mucosal margin of excision showed tumor in 12 (7.5%) cases.
  • Cause-specific survival at 5 years was significantly better for buccal cancer than floor of mouth cancer (P = .041).
  • On multivariate analysis patients with floor of mouth cancer were at a 3 times higher risk of dying of disease than those with buccal cancer.
  • CONCLUSION: In carefully selected patients, marginal mandibulectomy in buccal sulcus cancer achieves at least as good local control and survival as compared with the floor of mouth cancer.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Mandible / surgery. Mouth Neoplasms / surgery
  • [MeSH-minor] Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local

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  • (PMID = 19375004.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Joshi A, Rajendraprasad JS, Shetty K: Reconstruction of intraoral defects using facial artery musculomucosal flap. Br J Plast Surg; 2005 Dec;58(8):1061-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The facial artery musculomucosal flap, technically a combination of the nasolabial flap and the buccal mucosal flap, has been a reliable, versatile flap, either superiorly or inferiorly based for reconstruction of a wide variety of postcancer excision intraoral mucosal defects including defects of the palate, alveolus, lips and floor of mouth.
  • [MeSH-major] Mouth / surgery. Mouth Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Adolescent. Adult. Aged. Alveolar Process / surgery. Arteries. Child. Face / blood supply. Humans. Lip / surgery. Male. Middle Aged. Mouth Floor / surgery. Mouth Mucosa / surgery. Palate / surgery. Postoperative Complications / surgery. Reconstructive Surgical Procedures / methods

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  • (PMID = 16099439.001).
  • [ISSN] 0007-1226
  • [Journal-full-title] British journal of plastic surgery
  • [ISO-abbreviation] Br J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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71. Virk RS, Panda N, Ghosh S: Mylohyoid cysticercosis: a rare submandibular mass. Ear Nose Throat J; 2009 Nov;88(11):1218-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although skeletal muscle commonly harbors the cysticerci, we report a case in which they had infested the mylohyoid muscle in the floor of mouth, a site that has not been mentioned previously in the literature.
  • [MeSH-major] Cysticercosis / diagnosis. Neck Muscles / parasitology. Submandibular Gland / pathology. Submandibular Gland Diseases / parasitology

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  • (PMID = 19924665.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiprotozoal Agents; F4216019LN / Albendazole
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72. Gan K, Fung E, Idikio H, El-Hakim H: A floor of mouth teratoid cyst with tract in a newborn--case report and English literature review unraveling erroneous quotes and citations. Int J Pediatr Otorhinolaryngol; 2008 Aug;72(8):1275-9
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  • [Title] A floor of mouth teratoid cyst with tract in a newborn--case report and English literature review unraveling erroneous quotes and citations.
  • Floor of mouth teratoid cysts are the least common presentation reported.
  • Contrary to most reports, floor of mouth teratoid cysts are most commonly encountered in childhood with only a handful of cases in older age groups.
  • [MeSH-major] Mouth Neoplasms / surgery. Oral Fistula / surgery. Teratoma / surgery

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  • (PMID = 18550181.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 16
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73. Chong V: Oral cavity cancer. Cancer Imaging; 2005;5 Spec No A:S49-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Imaging information is essential for determining tumour resectibility, post resection surgical reconstruction and radiation therapy planning.
  • It focuses on buccal mucosa, hard palate, tongue and floor of mouth carcinoma.
  • [MeSH-major] Mouth Neoplasms / diagnosis
  • [MeSH-minor] Humans. Magnetic Resonance Imaging. Neoplasm Staging. Tomography, X-Ray Computed

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  • [Copyright] International Cancer Imaging Society.
  • [Cites] Head Neck. 1997 May;19(3):205-10 [9142520.001]
  • [Cites] Am J Surg. 2000 Aug;180(2):139-43 [11044531.001]
  • (PMID = 16361136.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1665311
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74. Ito FA, de Andrade CR, Vargas PA, Jorge J, Lopes MA: Primary tuberculosis of the oral cavity. Oral Dis; 2005 Jan;11(1):50-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this paper, we present a case of primary oral tuberculosis, affecting the floor of mouth in a 13-year-old Brazilian male patient.
  • [MeSH-minor] Adolescent. Biopsy. Diagnosis, Differential. Humans. Male. Mouth Floor

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  • (PMID = 15641968.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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75. Shehata E, Moussa K, Al-Gorashi A: A foreign body in the floor of the mouth. Saudi Dent J; 2010 Jul;22(3):141-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A foreign body in the floor of the mouth.
  • A case of unusual presentation of foreign body in the floor of mouth is reported.

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  • (PMID = 23960490.001).
  • [ISSN] 1013-9052
  • [Journal-full-title] The Saudi dental journal
  • [ISO-abbreviation] Saudi Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3723269
  • [Keywords] NOTNLM ; Foreign body / Marsupialisation / Ranula / Submandibular duct
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76. Shen J, Chen XM, Wang SZ, Wang L, Xiong SC: [Clinicopathological and immunohistochemical study of oral teratoid cyst]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2005 Jan;40(1):62-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Thirty-one cases of oral teratoid cyst according with Meyer's diagnosis criteria were retrospectively studied and their histochemistry and immunohistochemistry were performed from the files of Department of Pathology, School of Stomatology, Wuhan University between 1963 and 2003.
  • The ratio of male-to-female was 1:0.55, and the affected sites were floor of mouth (22 cases) and tongue (8 cases).
  • CONCLUSIONS: Oral teratoid cyst showed the highest incidence in children, and floor of mouth and tongue were mostly affected sites.
  • [MeSH-major] Mouth Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 15774156.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 68238-35-7 / Keratins
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77. Raguse JD, Bezeluk A, Bier J, Klein M: [The central island tongue flap for the reconstruction of the anterior floor of the mouth]. Mund Kiefer Gesichtschir; 2007 Jan;11(1):53-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The central island tongue flap for the reconstruction of the anterior floor of the mouth].
  • [Transliterated title] Der zentral gestielte myomucosale Zungenlappen zur Rekonstruktion des anterioren Mundbodens.
  • BACKGROUND: There are several techniques described for the reconstruction of the anterior floor of mouth after tumour surgery.
  • PATIENTS AND METHODS: We report on 20 patients with medium sized defect in the anterior floor of mouth, which was reconstructed with the central island tongue flap.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Mouth Floor / surgery. Mouth Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Mouth Rehabilitation / methods. Neoplasm Staging

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  • [Cites] Mund Kiefer Gesichtschir. 2000 May;4 Suppl 1:S278-85 [10938669.001]
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  • (PMID = 17216515.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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78. Viggor SF, Frezzini C, Farthing PM, Freeman CO, Yeoman CM, Thornhill MH: Amyloidosis: an unusual case of persistent oral ulceration. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Nov;108(5):e46-50
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  • The patient presented with extensive ulceration of the tongue and alveolar ridges, and a large swelling in the floor of mouth.
  • Incisional biopsies of the tongue and floor of mouth confirmed amyloid deposition within the tissues with evidence of necrotic ulceration.
  • Amyloid deposition in the oral cavity usually manifests as macroglossia, however it can present elsewhere in the mouth as nodular or plaquelike lesions.
  • This case highlights the variable nature of this condition, and how it can present a challenge to clinicians in terms of diagnosis and treatment.
  • [MeSH-minor] Aged. Amyloid / analysis. Fatal Outcome. Humans. Macroglossia / etiology. Male. Mouth Floor / chemistry. Mouth Floor / pathology. Multiple Myeloma / complications. Tongue / chemistry. Tongue / pathology

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  • (PMID = 19773186.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid
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79. El Khatib K, Danino A, Trost O, Jidal B, Malka G: [Use of nasolabial flap for mouth floor reconstruction]. Ann Chir Plast Esthet; 2005 Jun;50(3):216-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Use of nasolabial flap for mouth floor reconstruction].
  • [Transliterated title] Place du lambeau nasogénien dans les reconstructions du plancher buccal.
  • PURPOSE: The purpose of our study is to define the place and the limits of nasolabial flap in the reconstruction of the anterior floor of the mouth after tumoral resection compared to the other surgical and microsurgical techniques.
  • MATERIAL AND METHOD: We retrospectively studied patients with oral cancerous lesions of the anterior floor of the mouth reconstructed by nasolabial flap between 1997 and 2002.
  • The patients benefited from a surgical resection of the tumor by respecting the safety margins, with an immediate reconstruction allowing the restoring of the oral functions.
  • As complications, we noted one complete necrosis and two partial necrosis of the flap, two postoperative wound complications with dehiscence as well as a massive local recurrence of initial tumor in one patient.
  • CONCLUSION: The nasolabial flap represents a simple functional and morphological option to other pedicled or microsurgically anastomosed flaps for the reconstruction of intermediate-sized mouth floor defects.
  • [MeSH-major] Mouth Neoplasms / surgery. Neoplasm Recurrence, Local. Postoperative Complications. Reconstructive Surgical Procedures / methods. Surgical Flaps
  • [MeSH-minor] Aged. Female. Humans. Lip / surgery. Lymph Node Excision. Male. Middle Aged. Mouth Floor / surgery. Necrosis. Nose / surgery. Retrospective Studies. Treatment Outcome

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  • (PMID = 15896896.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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80. Vargas Fernández JL, Lorenzo Rojas J, Aneiros Fernández J, Sainz Quevedo M: [Dermoid cyst of the floor of the mouth]. Acta Otorrinolaringol Esp; 2007 Jan;58(1):31-3
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  • [Title] [Dermoid cyst of the floor of the mouth].
  • [Transliterated title] Quiste dermoide de suelo de boca.
  • We present a case of a male patient aged 53 years presenting tumouration on the floor of the mouth with an evolution of about 30 years.
  • [MeSH-major] Dermoid Cyst. Mouth Floor. Mouth Neoplasms

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  • (PMID = 17371676.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 15
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81. Yang XJ, Zheng JW, Zhou Q, Zhang SY, Yang C: Intracystic injection of pingyangmycin (PYM) might be a more favorable option for treatment of oral and plunging ranulas. Shanghai Kou Qiang Yi Xue; 2010 Aug;19(4):447-8
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  • Ranulas are mucoceles that develop as a result of mucous extravasation from the sublingual gland and typically present in the floor of mouth.

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  • (PMID = 20871968.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 11116-32-8 / bleomycetin
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82. Lin HW, O'Neill A, Rahbar R, Skinner ML: Ludwig's angina following frenuloplasty in an adolescent. Int J Pediatr Otorhinolaryngol; 2009 Sep;73(9):1313-5
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  • We present the case of a 13-year-old girl who underwent a frenuloplasty to correct speech disturbances and subsequently developed a life-threatening infection of the floor of mouth.

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  • (PMID = 19560216.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 3U02EL437C / Clindamycin
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83. Schmidt JE, Carlson CR, Usery AR, Quevedo AS: Effects of tongue position on mandibular muscle activity and heart rate function. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Dec;108(6):881-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study aimed to investigate masticatory muscle group activity and heart rate variability change when the tongue was placed on the palate or the floor of the mouth in a healthy pain-free sample.
  • The experimental protocol consisted of 3 periods: baseline, tongue placement on the floor of mouth, and tongue placement on palate.
  • RESULTS: Results indicated significantly more activity in the temporalis and suprahyoid muscle regions as well as a significant reduction in heart rate variability when the tongue was positioned on the palate compared with tongue position on the floor of the mouth.
  • CONCLUSIONS: Instructions to place the tongue on the roof of the mouth are not instructions that will promote reduced physiological functioning (i.e., relaxation) but rather promote small, but potentially important increases in overall activity as indexed by muscle tone and cardiac function.

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  • (PMID = 19773187.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Mueller DT, Callanan VP: Congenital malformations of the oral cavity. Otolaryngol Clin North Am; 2007 Feb;40(1):141-60, vii

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Congenital malformations of the oral cavity may involve the lips, jaws, hard palate, floor of mouth, and anterior two thirds of the tongue.
  • [MeSH-major] Mouth Abnormalities
  • [MeSH-minor] Choristoma / diagnosis. Gingival Neoplasms / congenital. Glossitis / surgery. Humans. Jaw Abnormalities. Labial Frenum / abnormalities. Lip / abnormalities. Macrostomia / surgery. Mandible / abnormalities. Maxilla / abnormalities. Micrognathism. Mucocele / surgery. Tongue / abnormalities

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  • (PMID = 17346565.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 35
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85. Pan CB, Li JS, Huang HZ, Huang ZQ, Zhao XP, Zhang B, Yang ZH, Wang YJ: [Combined repair of large defect caused by radical surgery of advanced tongue cancer with rib-major pectoralis myocutaneous flap carrying costal parietal pleura]. Zhonghua Wai Ke Za Zhi; 2006 Jul 1;44(13):911-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Six patients with advanced tongue carcinoma involving the floor of mouth and mandible were performed combined radical neck dissection with glossectomy and mandibulectomy, which caused large soft and hard tissue defect.
  • The rib flaps were applied for the repair of mandible, and the major pectoralis myocutaneous flaps were applied for the reconstruction of tongue and floor of mouth.
  • [MeSH-minor] Aged. Follow-Up Studies. Glossectomy. Humans. Male. Middle Aged. Mouth Floor / surgery. Neck Dissection. Transplantation, Autologous. Treatment Outcome

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  • (PMID = 17067485.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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86. Adappa ND, Sung CK, Choi B, Huang TG, Genden EM, Shin EJ: The administration of IL-12/GM-CSF and Ig-4-1BB ligand markedly decreases murine floor of mouth squamous cell cancer. Otolaryngol Head Neck Surg; 2008 Sep;139(3):442-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The administration of IL-12/GM-CSF and Ig-4-1BB ligand markedly decreases murine floor of mouth squamous cell cancer.
  • OBJECTIVE: To assess immune-based gene therapy in a murine floor of mouth (FOM) squamous cell carcinoma (SCC) model.
  • Intratumoral injections of viral vectors were administered with systemic Ig-4-1BB ligand in an orthotopic murine FOM SCC model and followed for tumor size and survival.
  • In vivo, tumors treated with advCMV-IL-12/GM-CSF and Ig-4-1BBL showed a striking reduction in tumor volume (vs control P<0.0001) and improved median survival (38 days vs 19 days for control, P<0.0001).
  • CONCLUSION: Combination immune-based therapies effectively improve survival in mice bearing FOM SCC over single-modality therapy.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Genetic Therapy / methods. Granulocyte-Macrophage Colony-Stimulating Factor / administration & dosage. Interleukin-12 / administration & dosage. Mouth Neoplasms / therapy
  • [MeSH-minor] Animals. Drug Synergism. Enzyme-Linked Immunosorbent Assay. Immunotherapy / methods. Mice. Mouth Floor. Time Factors. Tumor Cells, Cultured

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  • (PMID = 18722228.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 187348-17-0 / Interleukin-12; 83869-56-1 / Granulocyte-Macrophage Colony-Stimulating Factor
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87. Gaggl A, Bürger H, Chiari FM: The microvascular osteocutaneous femur transplant for covering combined alveolar ridge and floor of the mouth defects: preliminary report. J Reconstr Microsurg; 2008 Apr;24(3):169-75

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The microvascular osteocutaneous femur transplant for covering combined alveolar ridge and floor of the mouth defects: preliminary report.
  • The new flap was used for covering combined defects of the alveolar ridge and the neighboring floor of the mouth after tumor surgery and irradiation.
  • The microvascular osteocutaneous femur transplant can be used successfully in individual reconstruction of the alveolar ridge and the neighboring floor of the mouth after tumor resection.
  • [MeSH-major] Alveolar Process / surgery. Femur / transplantation. Mouth Floor / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Alveolar Ridge Augmentation / methods. Anastomosis, Surgical. Carcinoma, Squamous Cell / surgery. Humans. Male. Middle Aged. Mouth Neoplasms / surgery

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  • (PMID = 18454356.001).
  • [ISSN] 0743-684X
  • [Journal-full-title] Journal of reconstructive microsurgery
  • [ISO-abbreviation] J Reconstr Microsurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Civantos F, Zitsch R, Bared A: Sentinel node biopsy in oral squamous cell carcinoma. J Surg Oncol; 2007 Sep 15;96(4):330-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Preliminary data indicate that it may be useful for early oral cancers, with the exception of floor of mouth tumors, where technical challenges related to the proximity of the lymphatic basin remain a problem.
  • While central step sectioning and immunohistochemistry remain to be completed and analyzed, routine pathologic techniques provided negative predictive values of 96% for oral cancer excluding floor of mouth lesions.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Mouth Neoplasms / pathology. Mouth Neoplasms / surgery. Neck Dissection. Sentinel Lymph Node Biopsy / methods
  • [MeSH-minor] Clinical Trials as Topic. Drainage. Humans. Lymph Nodes / pathology. Lymphatic Metastasis. Neoplasm Staging. Predictive Value of Tests. Radioimmunodetection. Risk Factors

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  • (PMID = 17879335.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 49
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89. Huang ZQ, Li JS, Chen WL, Pan CB, Huang HZ, Zeng WK: [Application of multislice spiral CT and 3D reconstruction in diagnosis and treatment of vascular malformations in head and neck]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2009 Jan;25(1):28-31
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  • [Title] [Application of multislice spiral CT and 3D reconstruction in diagnosis and treatment of vascular malformations in head and neck].
  • OBJECTIVE: To explore the application of MS-CT and 3D reconstruction in diagnosis and treatment of vascular malformations in head and neck.
  • 12 cases of venous malformations in buccal and floor of mouth were treated with compartmentalized sclerotherapy with partial lesion involution.
  • 2 case of venous malformations in mouth floor were treated with operation followed by sclerotherpy with partial lesion involution.
  • CONCLUSION: MS-CT and 3D reconstruction can play an important role in diagnosis and treatment of vascular malformations in head and neck.

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  • (PMID = 19408721.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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90. Kirsch C: Oral cavity cancer. Top Magn Reson Imaging; 2007 Aug;18(4):269-80
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although oral cancer screening may be done on clinical examination, imaging plays a critical role in staging and determination of deep margins for either tumor resectability or radiation planning.
  • This article discusses the relevant anatomy on magnetic resonance imaging (MRI), including the lips and gingiva, floor of mouth, and oral tongue.
  • This is followed by a discussion of standard MRI techniques, American Joint Committee on Cancer (AJCC) classification, and relevant MRI findings with discussion and imaging examples of carcinoma in major sites, including floor of mouth, oral tongue, buccal mucosa, bony upper alveolus, hard palate, and retromolar trigone.
  • [MeSH-major] Mouth / pathology. Mouth Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Staging. Positron-Emission Tomography

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  • (PMID = 17893592.001).
  • [ISSN] 0899-3459
  • [Journal-full-title] Topics in magnetic resonance imaging : TMRI
  • [ISO-abbreviation] Top Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 63
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91. Reed MJ, Dunn MJ, McKeown DW: Can an airway assessment score predict difficulty at intubation in the emergency department? Emerg Med J; 2005 Feb;22(2):99-102
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  • Patients with large incisors (p<0.001), a reduced inter-incisor distance (p<0.05), or a reduced thyroid to floor of mouth distance (p<0.05) were all more likely to have a poor laryngoscopic view (grade 2, 3, or 4).
  • Patients with a poor laryngoscopic view (grades 2, 3, or 4) were more likely to have large incisors, a reduced inter-incisor distance, and a reduced thyroid to floor of mouth distance.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Head Movements. Humans. Incisor / anatomy & histology. Laryngoscopy. Male. Middle Aged. Mouth / anatomy & histology. Neck / anatomy & histology. Pharynx / anatomy & histology. Prospective Studies. Risk Assessment / methods

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  • (PMID = 15662057.001).
  • [ISSN] 1472-0213
  • [Journal-full-title] Emergency medicine journal : EMJ
  • [ISO-abbreviation] Emerg Med J
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1726680
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92. Murthy V, Agarwal JP, Laskar SG, Gupta T, Budrukkar A, Pai P, Chaturvedi P, Chaukar D, D'Cruz A: Analysis of prognostic factors in 1180 patients with oral cavity primary cancer treated with definitive or adjuvant radiotherapy. J Cancer Res Ther; 2010 Jul-Sep;6(3):282-9
MedlinePlus Health Information. consumer health - Oral Cancer.

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  • RESULTS: Of the entire cohort, 810 patients had tumors of the Gingivo-alveolo-buccal complex, lip and hard palate (Group 1) and 370 patients had primaries in tongue and floor of mouth (Group 2).
  • CONCLUSION: The results indicate superior outcomes with PORT particularly in advanced stages of oral cancer and inferior outcomes in tongue and floor of mouth subsites.
  • [MeSH-major] Mouth Neoplasms / radiotherapy

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  • (PMID = 21119254.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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93. Jham BC, Duraes GV, Jham AC, Santos CR: Epidermoid cyst of the floor of the mouth: a case report. J Can Dent Assoc; 2007 Jul-Aug;73(6):525-8
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  • [Title] Epidermoid cyst of the floor of the mouth: a case report.
  • The differential diagnosis for dermoid cysts includes infections, tumours, mucous extravasation phenomena and abnormalities arising during embryonic development.
  • In this case, aspiration of the cyst produced a keratin-containing liquid, which proved to be useful in preoperative diagnosis.
  • [MeSH-major] Epidermal Cyst / pathology. Mouth Diseases / pathology. Mouth Floor / pathology
  • [MeSH-minor] Adult. Cyst Fluid. Diagnosis, Differential. Humans. Male

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  • (PMID = 17672959.001).
  • [ISSN] 1488-2159
  • [Journal-full-title] Journal (Canadian Dental Association)
  • [ISO-abbreviation] J Can Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
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94. Civantos FJ, Zitsch RP, Schuller DE, Agrawal A, Smith RB, Nason R, Petruzelli G, Gourin CG, Wong RJ, Ferris RL, El Naggar A, Ridge JA, Paniello RC, Owzar K, McCall L, Chepeha DB, Yarbrough WG, Myers JN: Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: results of a prospective multi-institutional trial. J Clin Oncol; 2010 Mar 10;28(8):1395-400
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  • One hundred forty patients with invasive oral cancers, stage T1 and T2, N0 including 95 cancers of the tongue, 26 of the floor of mouth, and 19 other oral cancers were studied.
  • In the forty patients with proven cervical metastases, the true-positive rate was 90.2% and was superior for tongue tumors relative to floor of mouth.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology. Sentinel Lymph Node Biopsy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neck Dissection. Neoplasm Staging. Predictive Value of Tests. Prospective Studies. Reproducibility of Results

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  • (PMID = 20142602.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U10 CA076001; United States / NCI NIH HHS / CA / U24 CA114736; United States / NCI NIH HHS / CA / U24CA114736
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2834497
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95. Brandizzi D, Gandolfo M, Velazco ML, Cabrini RL, Lanfranchi HE: Clinical features and evolution of oral cancer: A study of 274 cases in Buenos Aires, Argentina. Med Oral Patol Oral Cir Bucal; 2008 Sep;13(9):E544-8
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  • Oral Squamous Cell Carcinoma has a low survival rate, 34 to 66% five-year survival after initial diagnosis, due to late diagnosis.
  • The tumor localizations with worse prognosis were floor of mouth and tongue, with survival rates of 19% and 27% respectively.
  • CONCLUSIONS: The patients under study exhibited the lowest survival rate described for oral cancer (34% five-year survival after initial diagnosis).
  • [MeSH-major] Carcinoma, Squamous Cell. Mouth Neoplasms

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  • (PMID = 18758396.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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96. Hornstra MT, Alkureishi LW, Ross GL, Shoaib T, Soutar DS: Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma. Head Neck; 2008 Jul;30(7):858-62
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  • Seven of the 12 patients had cT1/cT2 tumors, and 6 of these were located in the floor of mouth.
  • Factors associated with failure included T classification (p = .01), tumor site (p = .05), and negative preoperative lymphoscintigraphy (p = .0174).
  • CONCLUSION: Successful sentinel lymph node harvest is related to primary tumor site, T classification, and the presence of nodes on preoperative lymphoscintigraphy.
  • [MeSH-major] Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / secondary. Head and Neck Neoplasms / mortality. Head and Neck Neoplasms / pathology. Neoplasm Invasiveness / pathology. Sentinel Lymph Node Biopsy
  • [MeSH-minor] Adult. Aged. Chi-Square Distribution. Cohort Studies. Female. Humans. Immunohistochemistry. Lymph Nodes / pathology. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Predictive Value of Tests. Preoperative Care / methods. Probability. Retrospective Studies. Risk Assessment. Sensitivity and Specificity. Survival Analysis. Treatment Failure. Treatment Outcome

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  • (PMID = 18302276.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Warburton G, Nikitakis NG, Roberson P, Marinos NJ, Wu T, Sauk JJ Jr, Ord RA, Wahl SM: Histopathological and lymphangiogenic parameters in relation to lymph node metastasis in early stage oral squamous cell carcinoma. J Oral Maxillofac Surg; 2007 Mar;65(3):475-84
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  • MATERIALS AND METHODS: Clinical, histological, and immunohistochemical analyses were undertaken for 29 patients with T1N0M0 or T2N0M0 oral SCC affecting the tongue or floor of mouth and correlated with the development of DNM.
  • RESULTS: Tumor thickness, nuclear pleomorphism, pattern of invasion, and immunohistochemical expression of the lymphangiogenesis-associated molecules VEGFR-3 and VEGF-C were associated with DNM.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Lymphatic Metastasis / diagnosis. Mouth Neoplasms / pathology. Vascular Endothelial Growth Factor Receptor-3 / biosynthesis. Vascular Endothelial Growth Factors / biosynthesis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Immunoenzyme Techniques. Lymphangiogenesis / physiology. Male. Middle Aged. Neoplasm Staging. Prognosis. ROC Curve. Regression Analysis. Retrospective Studies. Sensitivity and Specificity. Vascular Endothelial Growth Factor C / analysis. Vascular Endothelial Growth Factor C / biosynthesis. Vascular Endothelial Growth Factor D / analysis. Vascular Endothelial Growth Factor D / biosynthesis

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  • (PMID = 17307596.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor C; 0 / Vascular Endothelial Growth Factor D; 0 / Vascular Endothelial Growth Factors; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-3
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98. McGee S, Mardirossian V, Elackattu A, Mirkovic J, Pistey R, Gallagher G, Kabani S, Yu CC, Wang Z, Badizadegan K, Grillone G, Feld MS: Anatomy-based algorithms for detecting oral cancer using reflectance and fluorescence spectroscopy. Ann Otol Rhinol Laryngol; 2009 Nov;118(11):817-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: We used reflectance and fluorescence spectroscopy to noninvasively and quantitatively distinguish benign from dysplastic/malignant oral lesions.
  • RESULTS: Discrimination of benign from dysplastic/malignant lesions was most successful when algorithms were designed for individual sites (area under the receiver operator characteristic curve [ROC-AUC],0.75 for the lateral surface of the tongue) and was least accurate when all sites were combined (ROC-AUC, 0.60).
  • The combination of sites with similar spectral properties (floor of mouth and lateral surface of the tongue) yielded an ROC-AUC of 0.71.
  • Anatomy-based algorithms for single sites or combinations of sites demonstrated good diagnostic performance in distinguishing benign lesions from dysplastic/malignant lesions and consistently performed better than algorithms developed for all sites combined.

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  • (PMID = 19999369.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA097966-05; United States / NCI NIH HHS / CA / R01-CA097966; United States / NCI NIH HHS / CA / R01 CA097966-05; United States / NCI NIH HHS / CA / R01 CA097966; United States / NCRR NIH HHS / RR / P41 RR002594; United States / NCRR NIH HHS / RR / P41 RR002594-24
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS189378; NLM/ PMC2860948
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99. Woolgar JA: The topography of cervical lymph node metastases revisited: the histological findings in 526 sides of neck dissection from 439 previously untreated patients. Int J Oral Maxillofac Surg; 2007 Mar;36(3):219-25
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  • The extent of metastasis (both volume and distribution) was greatest in tumours of the oropharynx followed by lateral tongue, ventral tongue and floor of mouth.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Lymphatic Metastasis / pathology. Mouth Neoplasms / pathology. Oropharyngeal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Lymph Nodes / pathology. Male. Middle Aged. Neck / pathology. Neck Dissection. Neoplasm Staging

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  • (PMID = 17239562.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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100. Bernhard MK, Hückel D, Hamala D: [Congenital ranula in a newborn]. HNO; 2007 May;55(5):388-91
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  • [Transliterated title] Sublinguale, livide Schwellung am Mundboden eines Neugeborenen: Kongenitale Ranula.
  • Ranulas are cystic lesions in the floor of the mouth.
  • We report the case of a premature newborn with a congenital ranula in the floor of mouth.
  • [MeSH-major] Ranula / congenital. Ranula / diagnosis. Salivary Gland Diseases / congenital. Salivary Gland Diseases / diagnosis. Sublingual Gland / pathology

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  • (PMID = 16770600.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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