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1. Pandit JJ, Buckler KJ: Halothane and sevoflurane exert different degrees of inhibition on carotid body glomus cell intracellular Ca2+ response to hypoxia. Adv Exp Med Biol; 2010;669:201-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Halothane and sevoflurane exert different degrees of inhibition on carotid body glomus cell intracellular Ca2+ response to hypoxia.
  • The purpose of this study was to ascertain if effects of halothane and sevoflurane (0.18-1.45 MAC) on the magnitude of the rise in intracellular calcium ([Ca(2+)]i with approximately 90s hypoxia (measured using indo-1 dye) in rat pup carotid body type I glomus cells. paralleled their known effects on the human hypoxic ventilatory response, where halothane is more depressive.
  • These actions reflect their known influence on human hypoxic ventilatory response, consistent with the notion that the cellular process underlies the whole-body effect.
  • [MeSH-major] Anoxia / metabolism. Calcium / metabolism. Carotid Body / cytology. Carotid Body / drug effects. Halothane / pharmacology. Intracellular Space / drug effects. Methyl Ethers / pharmacology

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  • (PMID = 20217349.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics; 0 / Methyl Ethers; 38LVP0K73A / sevoflurane; SY7Q814VUP / Calcium; UQT9G45D1P / Halothane
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2. Singh D, Pinjala RK, Reddy RC, Satya Vani PV: Management for carotid body paragangliomas. Interact Cardiovasc Thorac Surg; 2006 Dec;5(6):692-5
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  • [Title] Management for carotid body paragangliomas.
  • The carotid body tumor is a rare neoplasm that has generated much literature over the last century, and for which continued controversy exists regarding natural history, biologic behavior, proper technique of excision, and the risk of morbidity and mortality.
  • The present study reviewed a 16-year experience of managing carotid body paraganglioma (CBP) between 1988 and 2004.
  • In five patients the tumor excision was attempted before they were referred to our tertiary care hospital.

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  • (PMID = 17670685.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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3. Hu M, Zhang LH, Yang G, Chen LJ, Zhan X: [Selective embolization for surgical treatment of carotid body tumor]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2010 Aug;28(4):387-90
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  • [Title] [Selective embolization for surgical treatment of carotid body tumor].
  • OBJECTIVE: To investigate the value of carotid arteriography and selective embolization in surgical treatment of carotid body tumor.
  • METHODS: Seven patients with carotid body tumor were operated, and four patients were performed with carotid arteriography and selective embolization before operation.
  • All patients were treated by stripping the carotid body tumor from the carotid artery.
  • The CT scan and digital subtraction angiography (DSA) showed the tumor lesion in the carotid bifurcation, and the tumor and its relation with the surrounding arteries were expressed by CT and three dimensional CT images.
  • All cases of carotid body tumor were resected without any carotid artery ligation.
  • Preoperatively high-selected embolization of the tumor-feeding artery could effectively reduce the intraoperative bleeding.
  • With 1.5-3 years follow-up, none of the carotid body tumor recurred in all the seven cases.
  • CONCLUSION: Carotid arteriography and embolization therapy may decrease blood loss and higher risk for operation in the patients with carotid body tumor.
  • [MeSH-major] Carotid Body Tumor / therapy. Embolization, Therapeutic

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  • (PMID = 20848931.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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4. Wang ZY, Bisgard GE: Postnatal growth of the carotid body. Respir Physiol Neurobiol; 2005 Nov 15;149(1-3):181-90
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  • [Title] Postnatal growth of the carotid body.
  • The size of the carotid body (CB) is increased significantly during the postnatal period.
  • [MeSH-major] Carotid Body / growth & development. Respiratory Mechanics / physiology

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  • (PMID = 15914098.001).
  • [ISSN] 1569-9048
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL 68255
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Growth Substances; S88TT14065 / Oxygen
  • [Number-of-references] 59
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5. Torii S, Kobayashi K, Takahashi M, Katahira K, Goryo K, Matsushita N, Yasumoto K, Fujii-Kuriyama Y, Sogawa K: Magnesium deficiency causes loss of response to intermittent hypoxia in paraganglion cells. J Biol Chem; 2009 Jul 10;284(28):19077-89
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  • [Title] Magnesium deficiency causes loss of response to intermittent hypoxia in paraganglion cells.
  • Here we show that hypomagnesemia suppresses reactive oxygen species (ROS)-induced HIF-1alpha activity in paraganglion cells of the adrenal medulla and carotid body.
  • Also in the carotid body of magnesium-deficient mice, CoCl(2) and chronic intermittent hypoxia failed to enhance the tyrosine hydroxylase expression.

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  • [Cites] Biophys J. 1999 Dec;77(6):3034-42 [10585925.001]
  • [Cites] Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S42-5 [18845352.001]
  • [Cites] JAMA. 2000 Apr 12;283(14):1829-36 [10770144.001]
  • [Cites] N Engl J Med. 2000 May 11;342(19):1378-84 [10805822.001]
  • [Cites] Nature. 2001 Nov 29;414(6863):550-4 [11734856.001]
  • [Cites] Microsc Res Tech. 2002 Nov 1;59(3):178-87 [12384962.001]
  • [Cites] Physiol Rev. 2003 Jan;83(1):117-61 [12506128.001]
  • [Cites] J Biol Chem. 2003 Jun 20;278(25):22316-24 [12679337.001]
  • [Cites] JAMA. 2003 Oct 8;290(14):1906-14 [14532320.001]
  • [Cites] FASEB J. 2003 Dec;17(15):2187-93 [14656980.001]
  • [Cites] Hypertension. 2003 Dec;42(6):1130-6 [14597643.001]
  • [Cites] J Bioenerg Biomembr. 2003 Dec;35(6):533-75 [15000520.001]
  • [Cites] Neuroscience. 2004;126(2):313-23 [15207349.001]
  • [Cites] Nat Immunol. 2004 Aug;5(8):785-90 [15282562.001]
  • [Cites] Am J Respir Cell Mol Biol. 2004 Nov;31(5):544-51 [15256383.001]
  • [Cites] Science. 1980 Apr 11;208(4440):198-200 [7361117.001]
  • [Cites] Science. 1984 Mar 23;223(4642):1315-7 [6701524.001]
  • [Cites] J Membr Biol. 1995 Mar;144(1):1-9 [7595937.001]
  • [Cites] FEBS Lett. 1996 Oct 7;394(3):335-9 [8830669.001]
  • [Cites] J Bone Miner Res. 1998 Apr;13(4):749-58 [9556074.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7368-73 [9636155.001]
  • [Cites] Am J Physiol. 1999 Apr;276(4 Pt 2):H1313-22 [10199857.001]
  • [Cites] J Intensive Care Med. 2005 Jan-Feb;20(1):3-17 [15665255.001]
  • [Cites] EMBO J. 2005 Jan 26;24(2):315-24 [15616581.001]
  • [Cites] Science. 2005 Apr 1;308(5718):114-8 [15802604.001]
  • [Cites] Am J Respir Crit Care Med. 2005 Oct 1;172(7):915-20 [15976378.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Dec 9;338(1):617-26 [16139242.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Dec 9;338(1):627-38 [16153592.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Dec 9;338(1):610-6 [16154531.001]
  • [Cites] Circ Res. 2006 Jan 6;98(1):133-40 [16306444.001]
  • [Cites] Cancer Res. 2006 Feb 15;66(4):2257-63 [16489029.001]
  • [Cites] Mol Pharmacol. 2006 Nov;70(5):1469-80 [16887934.001]
  • [Cites] J Physiol. 2006 Dec 1;577(Pt 2):705-16 [16973705.001]
  • [Cites] Biochem Pharmacol. 2007 Feb 15;73(4):515-25 [17141738.001]
  • [Cites] Trends Immunol. 2007 Apr;28(4):161-8 [17336157.001]
  • [Cites] J Biol Chem. 2007 May 11;282(19):14073-82 [17355974.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1671-83 [17652356.001]
  • [Cites] Cell. 2007 Oct 19;131(2):364-77 [17956736.001]
  • [Cites] Curr Opin Pharmacol. 2008 Feb;8(1):33-41 [18203662.001]
  • [Cites] Cell Death Differ. 2008 Apr;15(4):686-90 [18259200.001]
  • [Cites] Oncogene. 1999 Nov 22;18(49):6853-66 [10602461.001]
  • (PMID = 19433582.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Small Interfering; 0 / Reactive Oxygen Species; EC 1.14.16.2 / Tyrosine 3-Monooxygenase; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC2707206
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6. Iturriaga R, Alcayaga J: Effects of intermittent hypoxia on cat petrosal ganglion responses induced by acetylcholine, adenosine 5'-triphosphate and NaCN. Brain Res; 2007 Jan 12;1128(1):86-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Exposure to chronic intermittent hypoxia (CIH) for 4 days enhances the cat carotid body (CB) chemosensory responses to acute hypoxia.
  • The dose-dependent curve parameters of the frequency of discharges evoked in the carotid sinus nerve by the application of ACh, ATP and NaCN to the isolated PG in control condition were not significantly modified in the CIH-treated cats.
  • [MeSH-minor] Action Potentials / drug effects. Analysis of Variance. Animals. Carotid Body / drug effects. Carotid Body / physiopathology. Cats. Dose-Response Relationship, Drug

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  • (PMID = 17125747.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 8L70Q75FXE / Adenosine Triphosphate; N9YNS0M02X / Acetylcholine; O5DDB9Z95G / Sodium Cyanide
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7. Penitente AR, Fernandes LG, Cardoso LM, Silva ME, Pedrosa ML, Silva AL, Haibara AS, Moraes MF, Chianca DA: Malnutrition enhances cardiovascular responses to chemoreflex activation in awake rats. Life Sci; 2007 Jul 26;81(7):609-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Interestingly, bilateral ligature of the carotid body arteries further increased baseline mean arterial pressure and heart rate in malnourished animals.
  • [MeSH-minor] Animals. Autonomic Nervous System / physiology. Blood Glucose / metabolism. Blood Pressure / physiology. Blood Proteins / metabolism. Carotid Arteries / physiology. Carotid Body / physiology. Diet. Heart Rate / drug effects. Male. Potassium Cyanide / pharmacology. Rats. Rats, Inbred F344. Serum Albumin / metabolism

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  • (PMID = 17688888.001).
  • [ISSN] 0024-3205
  • [Journal-full-title] Life sciences
  • [ISO-abbreviation] Life Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Blood Proteins; 0 / Serum Albumin; MQD255M2ZO / Potassium Cyanide
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8. Sjaastad O: SUNCT syndrome: The materialization of a headache syndrome. Clin Ophthalmol; 2008 Sep;2(3):533-43
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  • Carotid body, the principal peripheral chemoreceptor, seemed to function normally.

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  • [Cites] Cephalalgia. 1989 Jun;9(2):147-56 [2743414.001]
  • [Cites] Headache. 1989 Jun;29(6):373-6 [2759845.001]
  • [Cites] Cephalalgia. 1988 Sep;8(3):211-8 [3197101.001]
  • [Cites] Cephalalgia. 1987 Dec;7(4):273-84 [3427628.001]
  • [Cites] Br J Neurosurg. 1989;3(3):399-401 [2789726.001]
  • [Cites] Cephalalgia. 1981 Dec;1(4):233-44 [7347626.001]
  • [Cites] J Neurosurg. 1982 Dec;57(6):769-74 [7143059.001]
  • [Cites] Ann Neurol. 2005 Jun;57(6):924-7 [15929061.001]
  • [Cites] Headache. 1997 Jun;37(6):346-57 [9237408.001]
  • [Cites] Headache. 1997 Apr;37(4):195-202 [9150613.001]
  • [Cites] Headache. 1995 Jun;35(6):344-8 [7635720.001]
  • [Cites] Cephalalgia. 1993 Apr;13(2):108-13 [8495451.001]
  • [Cites] Cephalalgia. 1991 Jul;11(3):123-7 [1889067.001]
  • [Cites] Headache. 1992 Nov;32(10):489-95 [1468906.001]
  • [Cites] Headache. 1992 Sep;32(8):377-83 [1399558.001]
  • [Cites] Headache. 1991 Jun;31(6):399-405 [1889983.001]
  • [Cites] Circulation. 1981 Oct;64(4):753-9 [7273376.001]
  • [Cites] Neurology. 1972 Jan;22(1):92-8 [5061841.001]
  • [Cites] Acta Ophthalmol (Copenh). 1975 Dec;53(6):863-74 [1243232.001]
  • [Cites] Acta Ophthalmol (Copenh). 1975 Dec;53(6):856-62 [1243231.001]
  • [Cites] Acta Ophthalmol (Copenh). 1970;48(1):23-38 [5467713.001]
  • (PMID = 19668751.001).
  • [ISSN] 1177-5467
  • [Journal-full-title] Clinical ophthalmology (Auckland, N.Z.)
  • [ISO-abbreviation] Clin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC2694007
  • [Keywords] NOTNLM ; SUNCT syndrome / carotid body function / hypothalamic stimulation / intraocular blood flow / intraocular pressure / median artery blood flow
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9. Ayala-Ramirez M, Callender GG, Kupferman ME, Rich TA, Chuang HH, Trent J, Perrier ND, Goodarzi M, Jimenez C: Paraganglioma syndrome type 1 in a patient with Carney-Stratakis syndrome. Nat Rev Endocrinol; 2010 Feb;6(2):110-5
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  • He had no family history of carotid body tumors or pheochromocytoma.
  • DIAGNOSIS: Paraganglioma syndrome type 1 in a patient with a paraganglioma, bilateral pheochromocytomas and a gastrointestinal stromal tumor with a somatic Asp579del KIT mutation.
  • [MeSH-major] Gastrointestinal Stromal Tumors / diagnosis. Hypertension / diagnosis. Paraganglioma / diagnosis. Pheochromocytoma / diagnosis
  • [MeSH-minor] 3-Iodobenzylguanidine. Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / genetics. Adrenal Gland Neoplasms / surgery. Adult. Carney Complex. Chromogranin A / blood. Fluorodeoxyglucose F18. Gene Transfer Techniques. Humans. Lymphatic Metastasis. Male. Metanephrine / blood. Mutation. Neck. Positron-Emission Tomography. Proto-Oncogene Proteins c-kit / genetics. Succinate Dehydrogenase / genetics. Syndrome. Tomography, Emission-Computed, Single-Photon. Tomography, X-Ray Computed

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  • (PMID = 20098451.001).
  • [ISSN] 1759-5037
  • [Journal-full-title] Nature reviews. Endocrinology
  • [ISO-abbreviation] Nat Rev Endocrinol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chromogranin A; 0 / SDHD protein, human; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 35MRW7B4AD / 3-Iodobenzylguanidine; 5001-33-2 / Metanephrine; EC 1.3.99.1 / Succinate Dehydrogenase; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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10. Di Giulio C, Bianchi G, Cacchio M, Artese L, Rapino C, Macrì MA, Di Ilio C: Oxygen and life span: chronic hypoxia as a model for studying HIF-1alpha, VEGF and NOS during aging. Respir Physiol Neurobiol; 2005 May 12;147(1):31-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To test if oxygen sensitive mechanisms are affected by hypoxia, we studied hypoxia inducible factor-1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (iNOS) expression by immunohistochemical analysis in young and old rat carotid bodies (CBs) using hypoxia as a model for modulating aging.
  • In aged carotid body and in hypoxia the increased expression of HIF-1alpha, VEGF, iNOS is less evident as compared to the young one.
  • [MeSH-major] Aging. Anoxia / physiopathology. Carotid Body / metabolism. DNA-Binding Proteins / biosynthesis. Nitric Oxide Synthase / biosynthesis. Nuclear Proteins / biosynthesis. Transcription Factors / biosynthesis. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 15848121.001).
  • [ISSN] 1569-9048
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Hif1a protein, rat; 0 / Hypoxia-Inducible Factor 1; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / Vascular Endothelial Growth Factor A; EC 1.14.13.39 / Nitric Oxide Synthase
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11. Casserly P, Kiely P, Fenton JE: Cervical sympathetic chain schwannoma masquerading as a carotid body tumour with a postoperative complication of first-bite syndrome. Eur Arch Otorhinolaryngol; 2009 Oct;266(10):1659-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervical sympathetic chain schwannoma masquerading as a carotid body tumour with a postoperative complication of first-bite syndrome.
  • Carotid body tumours (CBT) are the most common tumours at the carotid bifurcation.
  • Radiologically, the mass was considered to be a CBT due to vascular enhancement and splaying of the internal and external carotid arteries.
  • The patient had a postoperative complication of first-bite syndrome (FBS).Although rare, CSCS should be considered in the differential diagnosis for tumours at the carotid bifurcation.
  • [MeSH-major] Autonomic Nervous System Diseases / diagnosis. Carotid Body Tumor / diagnosis. Head and Neck Neoplasms / diagnosis. Horner Syndrome / etiology. Neurilemmoma / diagnosis. Peripheral Nervous System Neoplasms / diagnosis. Postoperative Complications / etiology
  • [MeSH-minor] Carotid Artery, External / pathology. Carotid Artery, Internal / pathology. Diagnosis, Differential. Female. Humans. Jugular Veins / pathology. Magnetic Resonance Angiography. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • [Cites] Laryngoscope. 2004 Dec;114(12):2210-3 [15564847.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1989 Sep;18(1):53-8 [2807755.001]
  • [Cites] Eur Radiol. 2003 Jul;13(7):1608-11 [12835974.001]
  • [Cites] Radiology. 1987 Sep;164(3):823-9 [3039571.001]
  • [Cites] J Laryngol Otol. 1988 Oct;102(10):962-5 [3199023.001]
  • [Cites] J Laryngol Otol. 2000 Feb;114(2):119-24 [10748827.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2004 Sep;113(9):696-9 [15453525.001]
  • [Cites] Neurosurgery. 2001 Dec;49(6):1452-4 [11846946.001]
  • [Cites] Eur J Surg Oncol. 2002 Feb;28(1):88-90 [11869021.001]
  • [Cites] Henry Ford Hosp Med J. 1986;34(4):275-8 [3583794.001]
  • [Cites] Auris Nasus Larynx. 2008 Mar;35(1):109-13 [17851003.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1998 Oct;124(10):1133-40 [9776192.001]
  • [Cites] Ann Vasc Surg. 2000 Sep;14(5):519-24 [10990566.001]
  • [Cites] J Radiol. 2000 Sep;81(9):953-7 [10992092.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2000 Jan;109(1):48-51 [10651412.001]
  • [Cites] Curr Opin Otolaryngol Head Neck Surg. 2005 Dec;13(6):339-42 [16282761.001]
  • [Cites] Eur J Radiol. 2004 Dec;52(3):240-5 [15544901.001]
  • [Cites] Am Surg. 2000 Jan;66(1):52-5 [10651348.001]
  • [Cites] Head Neck. 2002 Nov;24(11):996-9 [12410534.001]
  • [Cites] Tumori. 2003 Mar-Apr;89(2):211-2 [12841675.001]
  • [Cites] Auris Nasus Larynx. 2002 Apr;29(2):215-7 [11893461.001]
  • [Cites] AJNR Am J Neuroradiol. 2004 May;25(5):863-70 [15140737.001]
  • [Cites] Tumori. 2005 Jan-Feb;91(1):84-6 [15850012.001]
  • [Cites] Ann Otol Rhinol Laryngol Suppl. 1981 Jan-Feb;90(1 Pt 4):3-15 [6258468.001]
  • (PMID = 19130071.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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12. Edwards BA, Sands SA, Skuza EM, Brodecky V, Stockx EM, Wilkinson MH, Berger PJ: Maturation of respiratory control and the propensity for breathing instability in a sheep model. J Appl Physiol (1985); 2009 Nov;107(5):1463-71
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  • We measured 1) carotid body sensitivity via dynamic ventilatory responses to step changes in O(2) and CO(2), 2) steady-state ventilatory sensitivity to CO(2) under hypoxic and hyperoxic conditions, 3) the dependence of the apneic threshold on arterial Po(2), and 4) the effect of hypoxic or hypercapnic gas inhalation during induced PB.

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  • (PMID = 19745191.001).
  • [ISSN] 1522-1601
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. Gupta AK, Purkayastha S, Bodhey NK, Kapilamoorthy TR, Kesavadas C: Preoperative embolization of hypervascular head and neck tumours. Australas Radiol; 2007 Oct;51(5):446-52
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  • Diagnosis of tumours was made on the basis of findings of imaging studies.
  • One patient (carotid body tumour) developed mild unilateral seventh, ninth and 10th cranial nerve palsy after transarterial embolization, transient hemiparesis was seen in another patient (nasopharyngeal angiofibroma).

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  • (PMID = 17803797.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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14. Rey S, Del Rio R, Alcayaga J, Iturriaga R: Endothelins in the cat petrosal ganglion and carotid body: effects and immunolocalization. Brain Res; 2006 Jan 19;1069(1):154-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endothelins in the cat petrosal ganglion and carotid body: effects and immunolocalization.
  • In response to hypoxia, chemoreceptor cells of the carotid body (CB) release transmitters, which acting on the petrosal ganglion (PG) neuron terminals, increase the chemoafferent discharge.
  • Thus, our data indicate that the excitatory effect of ET-1 in the carotid chemoreceptor system appears to be mainly due to a vasoconstrictor effect in the CB blood vessels.
  • [MeSH-major] Carotid Body / metabolism. Endothelin-1 / pharmacology. Endothelins / metabolism. Ganglia, Sensory / drug effects

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  • (PMID = 16364257.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Endothelin-1; 0 / Endothelins
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15. Rio RD, Moya EA, Alcayaga J, Iturriaga R: Evidence for histamine as a new modulator of carotid body chemoreception. Adv Exp Med Biol; 2009;648:177-84
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  • [Title] Evidence for histamine as a new modulator of carotid body chemoreception.
  • It has been proposed that histamine is an excitatory transmitter between the glomus cells of the carotid body (CB) and the nerve endings of the petrosal ganglion (PG) neurons.
  • However, there is no evidence that glomus cells contain histamine, or whether its application produces chemosensory excitation.
  • We found the presence of histamine immunoreactivity in dense-core vesicles in glomus cells.
  • The application of histamine hydrochloride (0.5-1,000 microg) to the CB produces a dose-dependent increase in the carotid sinus nerve activity.
  • Antagonism of the H3 receptor results in an increase in carotid body chemosensory activity.
  • On the other hand, application of histamine to the isolated PG had no effect on the carotid nerve discharge.
  • Our results suggest that histamine is a modulator of the carotid body chemoreception through H1 and H3 receptor activation.
  • [MeSH-major] Carotid Body / drug effects. Carotid Body / metabolism. Histamine / metabolism. Histamine / pharmacology

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  • (PMID = 19536479.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Histamine Antagonists; 820484N8I3 / Histamine; HPE317O9TL / Pyrilamine
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16. Koenigsberg RA, Vakil N, Noronha B: Undifferentiated metastatic carcinoma and myoepithelioma: two rare causes of hypervascular masses of the parapharyngeal space. Ear Nose Throat J; 2007 Jul;86(7):402-5
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  • The first case involved a poorly differentiated metastatic carcinoma of oropharyngeal origin that mimicked a carotid body tumor.
  • [MeSH-major] Myoepithelioma / diagnosis. Myoepithelioma / secondary. Neoplasms, Unknown Primary. Pharyngeal Neoplasms / diagnosis. Salivary Gland Neoplasms / secondary
  • [MeSH-minor] Aged. Carotid Body Tumor / diagnosis. Chromogranins / metabolism. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 17702321.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromogranins
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17. Dahan A, Sarton E, Teppema L: Plasticity in the brain: influence of bilateral carotid body resection (bCBR) on central CO2 sensitivity. Adv Exp Med Biol; 2008;605:312-6
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  • [Title] Plasticity in the brain: influence of bilateral carotid body resection (bCBR) on central CO2 sensitivity.
  • We investigated the effect of bilateral carotid body resection (bCBR) in a patient with bilateral carotid body tumors on central CO2 sensitivity.
  • These observations are a strong indication for (1) the existence of a tonic influence from the peripheral chemoreceptors of the carotid bodies on central CO2 drive;.
  • [MeSH-major] Brain / physiology. Carbon Dioxide / physiology. Carotid Body / physiology. Neuronal Plasticity. Respiratory Physiological Phenomena

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  • (PMID = 18085291.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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18. Donnelly DF, Kim I, Carle C, Carroll JL: Perinatal hyperoxia for 14 days increases nerve conduction time and the acute unitary response to hypoxia of rat carotid body chemoreceptors. J Appl Physiol (1985); 2005 Jul;99(1):114-9
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  • [Title] Perinatal hyperoxia for 14 days increases nerve conduction time and the acute unitary response to hypoxia of rat carotid body chemoreceptors.
  • [MeSH-major] Anoxia / embryology. Anoxia / physiopathology. Carotid Body / embryology. Carotid Body / physiopathology. Hyperoxia / embryology. Hyperoxia / physiopathology. Neural Conduction

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  • (PMID = 15731397.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL-054621; United States / NHLBI NIH HHS / HL / R01-HL-073500
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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19. Tan ZY, Lu Y, Whiteis CA, Benson CJ, Chapleau MW, Abboud FM: Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circ Res; 2007 Nov 9;101(10):1009-19
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  • [Title] Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells.
  • Carotid body chemoreceptors sense hypoxemia, hypercapnia, and acidosis and play an important role in cardiorespiratory regulation.
  • The molecular mechanism of pH sensing by chemoreceptors is not clear, although it has been proposed to be mediated by a drop in intracellular pH of carotid body glomus cells, which inhibits a K+ current.
  • Recently, pH-sensitive ion channels have been described in glomus cells that respond directly to extracellular acidosis.
  • In this study, we investigated the possible molecular mechanisms of carotid body pH sensing by recording the responses of glomus cells isolated from rat carotid body to rapid changes in extracellular pH using the whole-cell patch-clamping technique.
  • Extracellular acidosis evoked transient inward current in glomus cells that was inhibited by the acid-sensing ion channel (ASIC) blocker amiloride, absent in Na+-free bathing solution, and enhanced by either Ca2+-free buffer or addition of lactate.
  • In addition, ASIC1 and ASIC3 were shown to be expressed in rat carotid body by quantitative PCR and immunohistochemistry.
  • The results provide the first evidence that ASICs may contribute to chemotransduction of low pH by carotid body chemoreceptors and that extracellular acidosis directly activates carotid body chemoreceptors through both ASIC and TASK channels.
  • [MeSH-major] Acidosis / physiopathology. Acids / metabolism. Carotid Body / physiology. Chemoreceptor Cells / physiology. Membrane Proteins / physiology. Nerve Tissue Proteins / physiology. Sodium Channels / physiology

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  • [CommentIn] Circ Res. 2007 Nov 9;101(10):965-7 [17991889.001]
  • (PMID = 17872465.001).
  • [ISSN] 1524-4571
  • [Journal-full-title] Circulation research
  • [ISO-abbreviation] Circ. Res.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL14388-36
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Accn3 protein, rat; 0 / Acid Sensing Ion Channels; 0 / Acids; 0 / Asic1 protein, rat; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / RNA, Messenger; 0 / Sodium Channels; 9NEZ333N27 / Sodium; RWP5GA015D / Potassium; SY7Q814VUP / Calcium
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20. Morton RP, Stewart T, Dray MS, Farmilo W: A role for ipsilateral, selective neck dissection in carotid body tumours. J Laryngol Otol; 2009 Aug;123(8):934-6
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  • [Title] A role for ipsilateral, selective neck dissection in carotid body tumours.
  • INTRODUCTION: A reliable diagnosis of malignant carotid body tumour can only be made in the presence of metastatic disease, because the histological features of the primary tumour do not correlate with clinical behaviour.
  • CASE REPORT: We report two cases of malignant carotid body tumour in which regional nodal biopsy at the time of excision of the primary tumour revealed unsuspected metastatic disease.
  • DISCUSSION: Reoperation in the neck for recurrent metastatic carotid body tumour is difficult and potentially hazardous.
  • The presence of occult metastatic disease is easily identified if a selective - or sentinel - nodal dissection is performed routinely in cases of carotid body tumour excision.
  • [MeSH-major] Carotid Body Tumor / secondary. Head and Neck Neoplasms / secondary. Neck Dissection / methods

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  • (PMID = 19250592.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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21. Lahiri S, Mitchell CH, Reigada D, Roy A, Cherniack NS: Purines, the carotid body and respiration. Respir Physiol Neurobiol; 2007 Jul 1;157(1):123-9
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  • [Title] Purines, the carotid body and respiration.
  • The carotid body is essential to detecting levels of oxygen in the blood and initiating the compensatory response.
  • Increasing evidence suggests that the purines ATP and adenosine make a key contribution to this signaling by the carotid body.
  • The glomus cells release ATP in response to hypoxia.
  • This released ATP can stimulate P2X receptors on the carotid body to elevate intracellular Ca(2+) and to produce an excitatory response.
  • Endogenous adenosine stimulates these receptors to increase the ventilation rate and may modulate the catecholamine release from the carotid sinus nerve.
  • This review discusses evidence for a key role of ATP and adenosine in the hypoxic response of the carotid body, and emphasizes areas of new contributions likely to be important in the future.

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  • [Cites] Mol Pharmacol. 2000 Oct;58(4):771-7 [10999947.001]
  • [Cites] J Biol Chem. 2000 Dec 1;275(48):37572-81 [10978314.001]
  • [Cites] Br J Pharmacol. 1994 Apr;111(4):1252-6 [8032613.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] J Physiol. 1994 Jul 1;478 ( Pt 1):157-71 [7965831.001]
  • [Cites] Life Sci. 1995;57(8):773-83 [7637551.001]
  • [Cites] Br J Pharmacol. 1995 Aug;115(8):1415-24 [8564200.001]
  • [Cites] Br J Pharmacol. 1996 Apr;117(7):1371-3 [8730726.001]
  • [Cites] Prog Neurobiol. 1996 Feb;48(3):167-89 [8735876.001]
  • [Cites] Gen Pharmacol. 1996 Jun;27(4):613-20 [8853292.001]
  • [Cites] Br J Pharmacol. 1997 Jan;120(2):221-4 [9117113.001]
  • [Cites] Eur Respir J. 1997 Jan;10(1):156-60 [9032509.001]
  • [Cites] J Physiol. 1997 Mar 1;499 ( Pt 2):429-41 [9080372.001]
  • [Cites] J Appl Physiol (1985). 1997 Jun;82(6):1771-5 [9173940.001]
  • [Cites] Br J Pharmacol. 1997 Aug;121(7):1445-53 [9257926.001]
  • [Cites] J Neurophysiol. 1997 Dec;78(6):3069-76 [9405526.001]
  • [Cites] J Biol Chem. 1999 Feb 26;274(9):5972-80 [10026223.001]
  • [Cites] J Physiol. 1999 Mar 1;515 ( Pt 2):419-29 [10050009.001]
  • [Cites] Eur J Neurosci. 1999 Feb;11(2):673-81 [10051768.001]
  • [Cites] Mol Pharmacol. 1999 Oct;56(4):705-13 [10496952.001]
  • [Cites] Acta Physiol Scand. 1952 Jun 6;25(2-3):195-211 [12976137.001]
  • [Cites] J Neurophysiol. 2004 Dec;92(6):3433-45 [15056681.001]
  • [Cites] J Neurochem. 2000 Feb;74(2):621-32 [10646513.001]
  • [Cites] J Physiol. 2000 May 15;525 Pt 1:143-58 [10811733.001]
  • [Cites] Adv Exp Med Biol. 2000;475:549-58 [10849695.001]
  • [Cites] Brain Res. 2000 Jul 28;872(1-2):1-10 [10924669.001]
  • [Cites] Neurosci Lett. 2005 Jan 20;373(3):218-21 [15619546.001]
  • [Cites] J Neurosci. 2005 Feb 2;25(5):1211-8 [15689558.001]
  • [Cites] J Neurochem. 2005 Mar;92(6):1419-30 [15748160.001]
  • [Cites] Auton Neurosci. 2005 Jun 15;120(1-2):1-9 [15955746.001]
  • [Cites] Neurosci Lett. 1990 Nov 13;119(2):253-6 [1704113.001]
  • [Cites] J Physiol. 2005 Jul 15;566(Pt 2):491-503 [15890701.001]
  • [Cites] J Appl Physiol (1985). 2006 Jan;100(1):157-62 [16357082.001]
  • [Cites] Drug News Perspect. 2005 Oct;18(8):501-7 [16391720.001]
  • [Cites] Br J Pharmacol. 2006 Apr;147(7):783-9 [16444287.001]
  • [Cites] Pharmacol Ther. 2006 Jun;110(3):415-32 [16257449.001]
  • [Cites] J Neurochem. 2006 Jul;98(2):566-75 [16805847.001]
  • [Cites] J Neurosci. 2006 Sep 13;26(37):9482-93 [16971532.001]
  • [Cites] Respir Physiol Neurobiol. 2007 Apr 16;156(1):23-32 [16956797.001]
  • [Cites] Respir Physiol Neurobiol. 2007 Jul 1;157(1):106-15 [17276149.001]
  • [Cites] Biochem Pharmacol. 2001 Feb 15;61(4):443-8 [11226378.001]
  • [Cites] J Biol Chem. 2001 Apr 27;276(17):13838-46 [11278423.001]
  • [Cites] Neuroscience. 2001;104(3):633-42 [11440797.001]
  • [Cites] J Physiol. 2001 Dec 15;537(Pt 3):667-77 [11744746.001]
  • [Cites] Respir Physiol Neurobiol. 2002 Jun;130(3):223-33 [12093620.001]
  • [Cites] J Physiol. 2002 Sep 15;543(Pt 3):933-45 [12231649.001]
  • [Cites] Physiol Rev. 2002 Oct;82(4):1013-67 [12270951.001]
  • [Cites] Mol Pharmacol. 2003 Oct;64(4):785-95 [14500734.001]
  • [Cites] Respir Physiol Neurobiol. 2003 Oct 16;138(1):1-18 [14519374.001]
  • [Cites] J Appl Physiol (1985). 2004 Jan;96(1):384-91 [14660500.001]
  • [Cites] J Neurosci. 2003 Dec 10;23(36):11315-21 [14672995.001]
  • [Cites] J Appl Physiol (1985). 2004 Feb;96(2):765-73 [14715686.001]
  • [Cites] J Neurochem. 2004 Jun;89(5):1148-56 [15147507.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Sep 10;322(1):82-7 [15313176.001]
  • [Cites] Circ Res. 1974 Sep;35 Suppl 3:109-20 [4277988.001]
  • [Cites] Respir Physiol. 1975 Sep;24(3):249-66 [242049.001]
  • [Cites] Clin Perinatol. 1979 Mar;6(1):87-108 [383366.001]
  • [Cites] J Neurochem. 1979 Nov;33(5):999-1005 [228008.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1981 Jul;51(1):55-61 [7263424.001]
  • [Cites] Am J Physiol. 1982 Aug;243(2):H159-69 [7114227.001]
  • [Cites] Br J Pharmacol. 1983 Oct;80(2):347-54 [6317132.001]
  • [Cites] Br J Clin Pharmacol. 1985 Nov;20(5):503-6 [4074622.001]
  • [Cites] Br J Pharmacol. 1986 Jul;88(3):615-20 [3017488.001]
  • [Cites] J Appl Physiol (1985). 1986 Nov;61(5):1762-6 [3781985.001]
  • [Cites] J Pediatr. 1987 Apr;110(4):636-9 [3559816.001]
  • [Cites] Naunyn Schmiedebergs Arch Pharmacol. 1987 Feb;335(2):143-8 [3561527.001]
  • [Cites] Br J Clin Pharmacol. 1987 Mar;23(3):331-8 [3567048.001]
  • [Cites] Br J Clin Pharmacol. 1987 Apr;23(4):486-90 [3580255.001]
  • [Cites] J Appl Physiol (1985). 1987 Apr;62(4):1759-60 [3597248.001]
  • [Cites] J Appl Physiol (1985). 1987 Aug;63(2):685-91 [3654428.001]
  • [Cites] Acta Physiol Scand. 1987 Nov;131(3):459-65 [3425350.001]
  • [Cites] Science. 1988 Jul 29;241(4865):580-2 [2456613.001]
  • [Cites] Naunyn Schmiedebergs Arch Pharmacol. 1989 Aug;340(2):230-8 [2812035.001]
  • [Cites] Neurosci Lett. 1990 May 18;113(1):111-4 [2366949.001]
  • [Cites] Respir Physiol. 1990 May-Jun;80(2-3):299-306 [2218102.001]
  • [Cites] Eur J Clin Pharmacol. 1991;40(2):175-80 [2065697.001]
  • [Cites] Eur J Pharmacol. 1991 Nov 5;204(2):193-202 [1806387.001]
  • [Cites] Biochem J. 1992 Jul 15;285 ( Pt 2):345-65 [1637327.001]
  • [Cites] J Physiol. 1993 Jan;460:15-32 [8387583.001]
  • [Cites] J Appl Physiol (1985). 1993 Jun;74(6):3052-6 [8366007.001]
  • [Cites] J Appl Physiol (1985). 1993 Sep;75(3):1035-43 [8226509.001]
  • [Cites] Brain Res Mol Brain Res. 1993 Dec;20(4):313-27 [8114618.001]
  • [Cites] Br J Pharmacol. 1994 Jan;111(1):191-8 [8012696.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2000 Aug;279(2):L273-82 [10926550.001]
  • [Cites] Br J Clin Pharmacol. 2000 Aug;50(2):177-81 [10930971.001]
  • [Cites] Respir Physiol. 2000 Jul;121(2-3):199-208 [10963775.001]
  • (PMID = 17383945.001).
  • [ISSN] 1569-9048
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL50180; United States / NHLBI NIH HHS / HL / HL43413; United States / NHLBI NIH HHS / HL / R37 HL043413; United States / NEI NIH HHS / EY / EY015537; United States / NEI NIH HHS / EY / R01 EY015537; United States / NEI NIH HHS / EY / EY013434; United States / NHLBI NIH HHS / HL / R01 HL050180; United States / NEI NIH HHS / EY / R01 EY013434
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Purines
  • [Number-of-references] 97
  • [Other-IDs] NLM/ NIHMS23100; NLM/ PMC1975770
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22. Wyatt CN, Pearson SA, Kumar P, Peers C, Hardie DG, Evans AM: Key roles for AMP-activated protein kinase in the function of the carotid body? Adv Exp Med Biol; 2008;605:63-8
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  • [Title] Key roles for AMP-activated protein kinase in the function of the carotid body?
  • The carotid bodies play a critical role in initiating compensatory ventilatory responses to hypoxia.
  • However, the complete mechanism by which hypoxia excites the oxygen-sensing carotid body type 1 cells has not been fully defined.
  • We have previously proposed that the enzyme adenosine monophosphate-activated protein kinase (AMPK) may couple hypoxic inhibition of mitochondrial oxidative phosphorylation to carotid body type I cell excitation (Evans, Mustard, Wyatt, Peers, Dipp, Kumar, Kinnear and Hardie 2005).
  • Here we discuss evidence that AMPK is a key requirement for hypoxic chemotransduction by the carotid body.
  • In addition, we postulate upon a role for AMPK in the plasticity observed in the carotid body during both chronic and chronic intermittent hypoxia.
  • [MeSH-major] Carotid Body / physiology. Multienzyme Complexes / metabolism. Protein-Serine-Threonine Kinases / metabolism

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  • (PMID = 18085248.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 070772
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Multienzyme Complexes; 0 / Protein Subunits; EC 2.7.11.1 / AMP-Activated Protein Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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23. Ding Y, Li YL, Zimmerman MC, Schultz HD: Elevated mitochondrial superoxide contributes to enhanced chemoreflex in heart failure rabbits. Am J Physiol Regul Integr Comp Physiol; 2010 Feb;298(2):R303-11
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  • Here we investigated the role of manganese superoxide dismutase (MnSOD), the SOD isoform specially targeted to mitochondria, and mitochondrial superoxide levels in the enhanced chemoreceptor activity and function of the carotid body (CB) in CHF rabbits.
  • Adenovirus (Ad) MnSOD (1 x 10(8) plaque-forming units/ml) gene transfer selectively to the CBs normalized mitochondrial superoxide levels in glomus cells from CHF CB.
  • Compared with Ad Empty, Ad MnSOD reversed the blunted K(+) currents in CB glomus cells from CHF rabbits (385 + or - 11 vs. 551 + or - 20 pA/pF at +70 mV, P < 0.05).

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  • [Cites] Am J Cardiol. 1998 Aug 1;82(3):338-44 [9708664.001]
  • [Cites] Am J Cardiol. 1997 Dec 4;80(11A):7L-14L [9412538.001]
  • [Cites] J Appl Physiol (1985). 1999 Apr;86(4):1273-82 [10194213.001]
  • [Cites] Circ Res. 2005 Aug 5;97(3):260-7 [15994433.001]
  • [Cites] Heart Fail Rev. 2000 Mar;5(1):45-56 [16228915.001]
  • [Cites] N Engl J Med. 2005 Nov 10;353(19):2042-55 [16282179.001]
  • [Cites] Cardiovasc Res. 2006 Jul 1;71(1):129-38 [16650840.001]
  • [Cites] J Physiol. 2006 Aug 15;575(Pt 1):215-27 [16777942.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15038-43 [17015830.001]
  • [Cites] Circ Res. 2006 Oct 27;99(9):970-8 [17008601.001]
  • [Cites] Neuroscience. 2007 Mar 2;145(1):130-41 [17207576.001]
  • [Cites] Circulation. 2007 Jun 19;115(24):3095-102 [17548725.001]
  • [Cites] Hypertension. 2007 Jul;50(1):6-13 [17502495.001]
  • [Cites] J Neurochem. 2007 Aug;102(3):609-18 [17394531.001]
  • [Cites] Cardiovasc Res. 2007 Aug 1;75(3):546-54 [17499230.001]
  • [Cites] Nat Protoc. 2007;2(9):2295-301 [17853886.001]
  • [Cites] Biochim Biophys Acta. 2008 Jan;1777(1):1-14 [18036551.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H570-8 [18083891.001]
  • [Cites] Circ Res. 2008 Feb 29;102(4):488-96 [18096818.001]
  • [Cites] Nat Protoc. 2008;3(6):941-7 [18536642.001]
  • [Cites] J Appl Physiol (1985). 2008 Jul;105(1):14-23 [18356479.001]
  • [Cites] Biochem J. 2009 Jan 1;417(1):1-13 [19061483.001]
  • [Cites] Ann N Y Acad Sci. 2008 Dec;1147:37-52 [19076429.001]
  • [Cites] Hypertension. 2009 Feb;53(2):217-27 [19114648.001]
  • [Cites] Cardiovasc Res. 2009 Mar 1;81(4):678-85 [19091790.001]
  • [Cites] Med Clin North Am. 2009 May;93(3):621-35 [19427495.001]
  • [Cites] Free Radic Biol Med. 2009 Aug 15;47(4):333-43 [19427899.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1557-66 [19717736.001]
  • [Cites] J Appl Physiol (1985). 1999 Apr;86(4):1264-72 [10194212.001]
  • [Cites] J Appl Physiol (1985). 2000 May;88(5):1880-9 [10797153.001]
  • [Cites] Annu Rev Physiol. 2001;63:259-87 [11181957.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2516-23 [11356606.001]
  • [Cites] Circ Res. 2001 Jun 22;88(12):1259-66 [11420302.001]
  • [Cites] J Biol Chem. 2001 Oct 19;276(42):38388-93 [11507097.001]
  • [Cites] Circ Res. 2002 Nov 29;91(11):1038-45 [12456490.001]
  • [Cites] Prog Biophys Mol Biol. 2004 Feb-Apr;84(2-3):217-32 [14769437.001]
  • [Cites] J Physiol. 2004 Feb 15;555(Pt 1):219-29 [14673183.001]
  • [Cites] J Physiol. 2004 Apr 1;556(Pt 1):175-91 [14724184.001]
  • [Cites] J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):72A-84A [8376699.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] Adv Exp Med Biol. 1994;360:57-69 [7872130.001]
  • [Cites] Clin Cardiol. 1995 Mar;18(3 Suppl I):I3-8 [7743696.001]
  • [Cites] Prog Cardiovasc Dis. 1995 May-Jun;37(6):397-414 [7777669.001]
  • [Cites] Am Heart J. 1996 Oct;132(4):900-4 [8831388.001]
  • [Cites] Eur Heart J. 1997 Mar;18(3):480-6 [9076386.001]
  • [Cites] Circulation. 1997 Oct 21;96(8):2586-94 [9355898.001]
  • [CommentIn] Am J Physiol Regul Integr Comp Physiol. 2010 Feb;298(2):R301-2 [20007512.001]
  • (PMID = 19923358.001).
  • [ISSN] 1522-1490
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / P01 HL062222; United States / NCRR NIH HHS / RR / P20 RR017675; United States / NHLBI NIH HHS / HL / P01-HL62222
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Potassium Channels; 11062-77-4 / Superoxides; EC 1.15.1.1 / Superoxide Dismutase
  • [Other-IDs] NLM/ PMC2828171
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24. Ortiz FC, Varas R: Muscarinic modulation of TASK-like background potassium channel in rat carotid body chemoreceptor cells. Brain Res; 2010 Apr 6;1323:74-83
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  • [Title] Muscarinic modulation of TASK-like background potassium channel in rat carotid body chemoreceptor cells.
  • The carotid body is the main peripheral arterial chemoreceptor and it is essential to initiate the cardiovascular and respiratory compensatory reflex responses to a decrease in the arterial oxygen.
  • The carotid body chemoreceptor (type-I) cells respond to hypoxia with membrane depolarization, voltage-gated Ca(2+) entry and secretion of transmitters.
  • Since there is a proposed role for ACh as an autocrine/paracrine modulator of the carotid body function, we have investigated the possible regulation of the background K(+) current by mAChRs.
  • Our results suggest a muscarinic regulation of the TASK-like K(+) current in rat carotid body type-I cells through a PLC/PKC-dependent pathway.
  • Additionally, our findings are consistent with an autocrine/paracrine role for cholinergic autoreceptors present within the carotid body.
  • [MeSH-major] Carotid Body / physiology. Potassium Channels, Tandem Pore Domain / physiology. Receptors, Muscarinic / physiology

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20153302.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Muscarinic Agonists; 0 / Muscarinic Antagonists; 0 / Potassium Channels, Tandem Pore Domain; 0 / Receptors, Muscarinic; EC 2.7.11.13 / Protein Kinase C; SY7Q814VUP / Calcium
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25. Karaman E, Yilmaz M, Isildak H, Hacizade Y, Korkut N, Devranoğlu I, Enver O, Sekercioglu N: Management of jugular paragangliomas in otolaryngology practice. J Craniofac Surg; 2010 Jan;21(1):117-20
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  • Paragangliomas of the head and neck are highly vascular lesions originating from paraganglionic tissue located at the carotid bifurcation (carotid body tumors), along the vagus nerve (vagal paragangliomas), and in the jugular fossa and tympanic cavity and should be considered in the evaluation of all lateral neck masses.
  • Thirteen jugular paragangliomas (Fisch classifications C and D glomus jugulare) were treated in our institution during a period of 5 years (2003-2008).
  • All patients were subjected to digital subtraction angiography to define the vascular supply of the tumor.
  • The primary therapeutic option for jugular paragangliomas is complete excision of tumor with preservation of vital neurovascular structures.

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  • (PMID = 20061964.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Colinas O, Pérez-Carretero FD, López-López JR, Pérez-García MT: A role for DPPX modulating external TEA sensitivity of Kv4 channels. J Gen Physiol; 2008 May;131(5):455-71
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  • Kv4 are the molecular correlate of the A-type current of neurons (I(SA)), the fast component of I(TO) current in the heart, and also of the oxygen-sensitive K+ current (K(O2)) in rabbit carotid body (CB) chemoreceptor cells.
  • [MeSH-minor] Animals. Carotid Body / metabolism. Cells, Cultured. Chemoreceptor Cells / physiology. Gene Expression. Gene Silencing. Humans. Ion Transport / drug effects. Kinetics. Multiprotein Complexes / drug effects. Multiprotein Complexes / genetics. Multiprotein Complexes / metabolism. Oxygen / pharmacology. Patch-Clamp Techniques. Potassium Channel Blockers / pharmacology. Protein Subunits / genetics. Protein Subunits / metabolism. Rabbits

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  • [Cites] J Biol Chem. 1997 Dec 12;272(50):31598-603 [9395498.001]
  • [Cites] J Physiol. 1997 Mar 1;499 ( Pt 2):429-41 [9080372.001]
  • [Cites] Circ Res. 1998 Sep 7;83(5):560-7 [9734479.001]
  • [Cites] J Neurosci. 1998 Oct 15;18(20):8111-25 [9763458.001]
  • [Cites] J Gen Physiol. 1999 May;113(5):641-60 [10228180.001]
  • [Cites] Circ Res. 1999 Oct 1;85(7):623-33 [10506487.001]
  • [Cites] Mol Cell Neurosci. 2004 Dec;27(4):343-69 [15555915.001]
  • [Cites] Mol Cell Neurosci. 2005 Jun;29(2):320-32 [15911355.001]
  • [Cites] J Physiol. 2005 Jun 15;565(Pt 3):751-6 [15890703.001]
  • [Cites] J Physiol. 2005 Jul 15;566(Pt 2):395-408 [15890707.001]
  • [Cites] Physiol Rev. 2005 Oct;85(4):1205-53 [16183911.001]
  • [Cites] J Physiol. 2005 Nov 1;568(Pt 3):767-88 [16123112.001]
  • [Cites] J Physiol. 2005 Nov 15;569(Pt 1):7-39 [15831535.001]
  • [Cites] Brain Res. 2006 Jun 13;1094(1):1-12 [16764835.001]
  • [Cites] J Neurochem. 2007 Jul;102(2):333-44 [17561939.001]
  • [Cites] J Neurosci. 2000 Jan 15;20(2):579-88 [10632587.001]
  • [Cites] Nature. 2000 Feb 3;403(6769):553-6 [10676964.001]
  • [Cites] J Physiol. 2000 Jun 1;525 Pt 2:285-98 [10835033.001]
  • [Cites] J Neurosci. 2000 Aug 1;20(15):5689-95 [10908607.001]
  • [Cites] Circ Res. 2001 May 25;88(10):1012-9 [11375270.001]
  • [Cites] Biophys J. 2001 Aug;81(2):867-83 [11463631.001]
  • [Cites] J Physiol. 2001 Aug 15;535(Pt 1):65-81 [11507158.001]
  • [Cites] J Neurosci. 2001 Oct 15;21(20):8004-14 [11588173.001]
  • [Cites] Methods. 2001 Dec;25(4):402-8 [11846609.001]
  • [Cites] Pflugers Arch. 2002 Feb;443(4):664-70 [11907835.001]
  • [Cites] J Physiol. 2002 Jul 15;542(Pt 2):369-82 [12122138.001]
  • [Cites] J Biol Chem. 2002 Jul 26;277(30):26904-11 [12006572.001]
  • [Cites] Neuron. 2003 Feb 6;37(3):449-61 [12575952.001]
  • [Cites] Adv Exp Med Biol. 2003;536:33-9 [14635646.001]
  • [Cites] J Physiol. 2004 Jun 1;557(Pt 2):457-71 [15034123.001]
  • [Cites] Biophys J. 2004 Oct;87(4):2380-96 [15454437.001]
  • [Cites] Neuron. 1988 Oct;1(8):649-58 [3272183.001]
  • [Cites] Proc Natl Acad Sci U S A. 1991 May 15;88(10):4386-90 [2034678.001]
  • [Cites] Neuron. 1991 Sep;7(3):471-83 [1840649.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):197-201 [1729689.001]
  • [Cites] Am J Physiol. 1992 Dec;263(6 Pt 1):C1152-9 [1476161.001]
  • [Cites] J Physiol. 1993 Jan;460:15-32 [8387583.001]
  • [Cites] J Gen Physiol. 1993 Oct;102(4):713-28 [7903683.001]
  • [Cites] J Neurophysiol. 1994 Oct;72(4):1516-29 [7823083.001]
  • [Cites] Biophys J. 1997 Jan;72(1):163-74 [8994601.001]
  • [Cites] Mol Pharmacol. 1997 Mar;51(3):491-8 [9058605.001]
  • [Cites] J Neurosci. 1998 May 1;18(9):3124-37 [9547221.001]
  • (PMID = 18411327.001).
  • [ISSN] 1540-7748
  • [Journal-full-title] The Journal of general physiology
  • [ISO-abbreviation] J. Gen. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Multiprotein Complexes; 0 / Potassium Channel Blockers; 0 / Protein Subunits; 0 / Shal Potassium Channels; 66-40-0 / Tetraethylammonium; EC 3.4.14.- / Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; S88TT14065 / Oxygen
  • [Other-IDs] NLM/ PMC2346566
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27. Girolami A, Ruzzon E, Tezza F, Scandellari R, Scapin M, Scarparo P: Congenital FX deficiency combined with other clotting defects or with other abnormalities: a critical evaluation of the literature. Haemophilia; 2008 Mar;14(2):323-8
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  • Isolated FX deficiency and, more frequently, combined FX + FVII deficiency appear also associated with coagulation-unrelated abnormalities (carotid body tumours, mitral valve prolapse, atrial septal defect, ventricular septal defect, thrombocytopenia absent radius (TAR) syndrome, mental retardation, microcephaly and cleft palate).
  • Diagnosis of a combined clotting defect could be difficult on the basis of global tests.
  • Only specific assays could allow one to reach the correct diagnosis.

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  • (PMID = 18081833.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 9001-25-6 / Factor VII; 9001-27-8 / Factor VIII; 9001-29-0 / Factor X
  • [Number-of-references] 30
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28. Matikainen J, Elo H: Does yawning increase arousal through mechanical stimulation of the carotid body? Med Hypotheses; 2008;70(3):488-92
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  • [Title] Does yawning increase arousal through mechanical stimulation of the carotid body?
  • Whilst yawning has been speculated to have an important role in reversing hypoxia, there is a structure in the neck that is known to be intimately involved in the regulation of oxygen homeostasis, namely the carotid body.
  • In spite of this, a connection has never been proposed either between the carotid body and arousal, or between yawning and the carotid body.
  • We propose that yawning stimulates mechanically the carotid body (and possibly other structures in the neck).
  • We also propose that mechanical effects on the shunt system of the carotid body may be involved in this stimulation.
  • For example, yawning causes movements and compressions that may affect the carotid body that is situated strategically at the bifurcation of the common carotid artery.
  • Thus, yawning may stimulate the carotid body.
  • The carotid body is highly vascular and compressions may affect its shunt system and blood flow and for example give rise to release of hormones or other substances.
  • [MeSH-major] Arousal / physiology. Carotid Body / physiology. Yawning / physiology

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  • [CommentIn] Med Hypotheses. 2008 Aug;71(2):307 [18434039.001]
  • (PMID = 17709210.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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29. Balbir A, Lande B, Fitzgerald RS, Polotsky V, Mitzner W, Shirahata M: Behavioral and respiratory characteristics during sleep in neonatal DBA/2J and A/J mice. Brain Res; 2008 Nov 19;1241:84-91
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  • The ventilatory response to hypoxia depends on the carotid body function and sleep-wake states.
  • (1) if EMG can be eliminated for assessing sleep-wake states; and (2) behavioral characteristics and carotid body-mediated respiratory control during sleep with EMG (EMG+) or without EMG (EMG-).
  • Carotid body-mediated respiratory responses (decreased ventilation upon hyperoxia and increased ventilation upon mild hypoxia) during sleep were clearly observed in these neonatal mice with or without EMG instrumentation.

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  • [Cites] J Appl Physiol (1985). 2001 Dec;91(6):2758-66 [11717244.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2007 Mar;292(3):L704-15 [17098806.001]
  • [Cites] Behav Brain Res. 2002 Nov 15;136(2):489-501 [12429412.001]
  • [Cites] J Appl Physiol (1985). 2003 Apr;94(4):1536-42 [12626474.001]
  • [Cites] Am J Respir Crit Care Med. 2003 Dec 15;168(12):1520-7 [14512266.001]
  • [Cites] Neuroscience. 2004;123(2):575-82 [14698764.001]
  • [Cites] Sleep. 1980;3(1):83-92 [7466128.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1981 Jul;51(1):40-5 [7263422.001]
  • [Cites] Pediatr Res. 1987 Jun;21(6):556-62 [3601474.001]
  • [Cites] J Appl Physiol (1985). 1990 Feb;68(2):441-51 [2180894.001]
  • [Cites] Annu Rev Physiol. 1991;53:71-85 [2042977.001]
  • [Cites] J Appl Physiol (1985). 1993 Dec;75(6):2383-91 [8125854.001]
  • [Cites] J Physiol. 1994 Mar 1;475(2):267-75 [8021833.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] Exp Physiol. 1996 Jan;81(1):1-26 [8869137.001]
  • [Cites] Am J Physiol. 1997 Jun;272(6 Pt 2):R1792-9 [9227592.001]
  • [Cites] J Appl Physiol (1985). 1998 Jul;85(1):366-71 [9655797.001]
  • [Cites] Respir Physiol. 1998 May;112(2):215-25 [9716305.001]
  • [Cites] Dev Psychobiol. 1998 Sep;33(2):107-23 [9742406.001]
  • [Cites] J Physiol. 1999 Jan 15;514 ( Pt 2):493-503 [9852330.001]
  • [Cites] Am J Physiol. 1999 May;276(5 Pt 1):L875-84 [10330044.001]
  • [Cites] Pediatrics. 1955 Jul;16(1):81-7 [14394741.001]
  • [Cites] Am J Respir Crit Care Med. 2005 Jul 15;172(2):238-43 [15860752.001]
  • [Cites] Semin Respir Crit Care Med. 2005 Feb;26(1):5-12 [16052413.001]
  • [Cites] Adv Exp Med Biol. 2006;580:99-104; discussion 351-9 [16683704.001]
  • [Cites] Physiol Genomics. 2007 Jan 17;28(2):232-8 [16985007.001]
  • [Cites] Behav Neurosci. 2002 Oct;116(5):912-7 [12369810.001]
  • (PMID = 18817755.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL072293-04; United States / NHLBI NIH HHS / HL / R01 HL081345-02; United States / NHLBI NIH HHS / HL / HL081345-02; United States / NHLBI NIH HHS / HL / R01 HL050712; United States / NHLBI NIH HHS / HL / HL072293-04; United States / NHLBI NIH HHS / HL / HL50712; United States / NHLBI NIH HHS / HL / R01 HL081345-01A2; United States / NHLBI NIH HHS / HL / HL72293; United States / NHLBI NIH HHS / HL / HL081345-01A2; United States / NHLBI NIH HHS / HL / HL050712-14; United States / NHLBI NIH HHS / HL / T32 HL007534-26; United States / NHLBI NIH HHS / HL / HL81345; United States / NHLBI NIH HHS / HL / T32-HL07534; United States / NHLBI NIH HHS / HL / R01 HL050712-14; United States / NHLBI NIH HHS / HL / R01 HL081345; United States / NHLBI NIH HHS / HL / R01 HL072293; United States / NHLBI NIH HHS / HL / HL007534-26; United States / NHLBI NIH HHS / HL / T32 HL007534
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS82924; NLM/ PMC2635892
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30. Julien CA, Niane L, Kinkead R, Bairam A, Joseph V: Carotid sinus nerve stimulation, but not intermittent hypoxia, induces respiratory LTF in adult rats exposed to neonatal intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol; 2010 Jul;299(1):R192-205
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carotid sinus nerve stimulation, but not intermittent hypoxia, induces respiratory LTF in adult rats exposed to neonatal intermittent hypoxia.
  • In anesthetized rats, phrenic and splanchnic nerve activities and hypoxic responses were also recorded with or without intact carotid body afferent signal (bilateral chemodenervation) or in response to electrical stimulations of the carotid sinus nerve.
  • In anesthetized rats, phrenic nerve responses to repeated hypoxic cycles or carotid sinus nerve stimulation were not altered by n-IH; however, the splanchnic nerve response was suppressed by n-IH compared with control.
  • [MeSH-major] Anoxia / physiopathology. Carotid Sinus / innervation. Respiratory System / physiopathology
  • [MeSH-minor] Animals. Animals, Newborn. Arteries / physiopathology. Blood Pressure / physiology. Carotid Body / physiopathology. Central Nervous System / physiopathology. Chemoreceptor Cells. Electric Stimulation. Male. Phrenic Nerve / physiopathology. Rats. Rats, Inbred Strains. Respiration. Splanchnic Nerves / physiopathology

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  • (PMID = 20410478.001).
  • [ISSN] 1522-1490
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / / XG07-006
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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31. Duprat F, Lauritzen I, Patel A, Honoré E: The TASK background K2P channels: chemo- and nutrient sensors. Trends Neurosci; 2007 Nov;30(11):573-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Moreover, hypoxic down-modulation of TASK channels is implicated in the activation of glomus cells in the carotid body.

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  • (PMID = 17945357.001).
  • [ISSN] 0166-2236
  • [Journal-full-title] Trends in neurosciences
  • [ISO-abbreviation] Trends Neurosci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Nerve Tissue Proteins; 0 / Potassium Channels, Tandem Pore Domain; 0 / potassium channel subfamily K member 3; IY9XDZ35W2 / Glucose; S88TT14065 / Oxygen
  • [Number-of-references] 72
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32. Jeffery J, Devendra D, Farrugia J, Gardner D, Murphy MJ, Williams R, Ayling RM, Wilkin TJ: Increased urinary dopamine excretion in association with bilateral carotid body tumours-- clinical, biochemical and genetic findings. Ann Clin Biochem; 2006 Mar;43(Pt 2):156-60
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  • [Title] Increased urinary dopamine excretion in association with bilateral carotid body tumours-- clinical, biochemical and genetic findings.
  • This report describes a rare case of a patient with increased urinary dopamine excretion in association with bilateral carotid body tumours.
  • Excretion of adrenaline, noradrenaline, metadrenaline, normetadrenaline and 4-hydroxy-3-methoxymandelic acid (HMMA) were within the reference ranges, and an (123)I-meta-iodobenzylguanidine (MIBG) scan showed uptake in the neck masses, with no other abnormal uptake anywhere else in the body.
  • There are only four previous case reports of dopamine-secreting tumours of the carotid body described in the literature, all of whom were women.
  • Familial cases of carotid body tumours have a higher prevalence of bilateral tumours than non-familial cases.
  • [MeSH-major] Carotid Body Tumor / genetics. Carotid Body Tumor / radiography. Dopamine / urine. Succinate Dehydrogenase / genetics
  • [MeSH-minor] 3-Iodobenzylguanidine / analysis. Carotid Body / radiography. Catecholamines / urine. Humans. Male. Middle Aged. Mutation. Tomography, X-Ray Computed

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  • (PMID = 16536919.001).
  • [ISSN] 0004-5632
  • [Journal-full-title] Annals of clinical biochemistry
  • [ISO-abbreviation] Ann. Clin. Biochem.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Catecholamines; 35MRW7B4AD / 3-Iodobenzylguanidine; EC 1.3.99.1 / Succinate Dehydrogenase; VTD58H1Z2X / Dopamine
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33. Kåhlin J, Eriksson LI, Ebberyd A, Fagerlund MJ: Presence of nicotinic, purinergic and dopaminergic receptors and the TASK-1 K+-channel in the mouse carotid body. Respir Physiol Neurobiol; 2010 Jul 31;172(3):122-8
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  • [Title] Presence of nicotinic, purinergic and dopaminergic receptors and the TASK-1 K+-channel in the mouse carotid body.
  • We have characterized the mouse carotid body (CB) with special attention to nicotinic, purinergic and dopaminergic receptors as well as the TASK-1 K(+)-channel.
  • [MeSH-major] Carotid Body / metabolism. Nerve Tissue Proteins / metabolism. Potassium Channels, Tandem Pore Domain / metabolism. Receptors, Dopamine / metabolism. Receptors, Nicotinic / metabolism. Receptors, Purinergic / metabolism

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20452469.001).
  • [ISSN] 1878-1519
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Nerve Tissue Proteins; 0 / Neurofilament Proteins; 0 / Potassium Channels, Tandem Pore Domain; 0 / Receptors, Dopamine; 0 / Receptors, Nicotinic; 0 / Receptors, Purinergic; 0 / Receptors, Purinergic P2; 0 / Receptors, Purinergic P2X; 0 / Tubulin; 0 / potassium channel subfamily K member 3; EC 1.14.16.2 / Tyrosine 3-Monooxygenase
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34. Bozgeyik Z, Kocakoc E: Dynamic flow (B-flow) versus power Doppler imaging in a case of carotid body tumor. J Clin Ultrasound; 2007 Jul-Aug;35(6):331-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dynamic flow (B-flow) versus power Doppler imaging in a case of carotid body tumor.
  • [MeSH-major] Carotid Body Tumor / ultrasonography. Ultrasonography, Doppler / methods
  • [MeSH-minor] Adult. Carotid Artery, External / ultrasonography. Carotid Artery, Internal / ultrasonography. Humans. Male. Neck / blood supply

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  • (PMID = 17486569.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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35. Lam SY, Liong EC, Tipoe GL, Fung ML: Expression of HIF-2alpha and HIF-3alpha in the rat carotid body in chronic hypoxia. Adv Exp Med Biol; 2006;580:29-36; discussion 351-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of HIF-2alpha and HIF-3alpha in the rat carotid body in chronic hypoxia.
  • [MeSH-major] Anoxia / genetics. Anoxia / metabolism. Carotid Body / metabolism. Transcription Factors / genetics. Transcription Factors / metabolism

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  • (PMID = 16683694.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / DNA, Complementary; 0 / Hif3a protein, rat; 0 / RNA, Messenger; 0 / Transcription Factors; 0 / endothelial PAS domain-containing protein 1
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36. Dalainas I, Nano G, Casana R, Bianchi P, Stegher S, Malacrida G, Tealdi DG: Carotid body tumours. A 20-year single-institution experience. Chir Ital; 2006 Sep-Oct;58(5):631-5
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  • [Title] Carotid body tumours. A 20-year single-institution experience.
  • The aim of this single-institution retrospective study was to review the surgical outcomes of resection of carotid body tumours over the last 20 years in our hospital.
  • From January 1985 to December 2004, 17 patients were admitted to our institution with carotid body tumours.
  • Perioperative comorbidities were more frequent in patients with large carotid body tumours intimately associated with the carotid vessels.
  • Surgical excision of carotid body tumours is safe and effective even in the long term.
  • [MeSH-major] Carotid Body Tumor / surgery
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 17069193.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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37. Gulbransen BD, Finger TE: Solitary chemoreceptor cell proliferation in adult nasal epithelium. J Neurocytol; 2005 Mar;34(1-2):117-22
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  • While some populations of sensory cells are replaced throughout life (taste and olfaction), others are not (hair cells and carotid body chemoreceptors).

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  • [Cites] Respir Physiol. 1994 Apr;96(1):37-48 [8023019.001]
  • [Cites] J Neurosci. 1997 May 15;17(10):3610-22 [9133384.001]
  • [Cites] Chem Senses. 1998 Dec;23(6):735-42 [9915120.001]
  • [Cites] Prog Neurobiol. 2005 Mar;75(4):295-307 [15882778.001]
  • [Cites] J Appl Physiol (1985). 1995 Nov;79(5):1504-11 [8594006.001]
  • [Cites] J Neurobiol. 2000 Apr;43(1):50-63 [10756066.001]
  • [Cites] Anat Embryol (Berl). 2000 Nov;202(5):359-67 [11089927.001]
  • [Cites] J Comp Neurol. 2003 May 5;459(3):209-22 [12655505.001]
  • [Cites] BMC Neurosci. 2001;2:6 [11346454.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8981-6 [12857948.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2004 Mar;45(3):971-6 [14985319.001]
  • [Cites] Curr Biol. 2004 Feb 3;14(3):R127-8 [14986686.001]
  • [Cites] Chem Senses. 2004 Oct;29(8):683-92 [15466813.001]
  • [Cites] J Cell Biol. 1965 Nov;27(2):263-72 [5884625.001]
  • [Cites] Ann N Y Acad Sci. 1974 Sep 27;237(0):52-61 [4214101.001]
  • [Cites] Cell Tissue Kinet. 1980 Jul;13(4):349-57 [7428010.001]
  • [Cites] J Anat. 1982 Aug;135(Pt 1):83-8 [7130058.001]
  • [Cites] Med Biol. 1983;61(5):229-48 [6323893.001]
  • [Cites] J Pathol. 1985 Nov;147(3):181-7 [4067736.001]
  • [Cites] Acta Derm Venereol. 1987;67(6):517-20 [2451378.001]
  • [Cites] Brain Res. 1988 Aug 2;457(1):44-52 [3167568.001]
  • [Cites] Neuron. 1990 Mar;4(3):461-7 [2138470.001]
  • [Cites] Am J Physiol. 1990 Aug;259(2 Pt 1):L38-46 [2200283.001]
  • (PMID = 16374713.001).
  • [ISSN] 0300-4864
  • [Journal-full-title] Journal of neurocytology
  • [ISO-abbreviation] J. Neurocytol.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC004657-059002; United States / NIDCD NIH HHS / DC / P30 DC004657; United States / NIDCD NIH HHS / DC / DC004657-069002; United States / NIDCD NIH HHS / DC / R01 DC 006070; United States / NIDCD NIH HHS / DC / P30 DC 04657; United States / NIDCD NIH HHS / DC / P30 DC004657-069002; United States / NIDCD NIH HHS / DC / P30 DC004657-059002; United States / NIDCD NIH HHS / DC / R01 DC006070-02; United States / NIDCD NIH HHS / DC / DC006070-01; United States / NIDCD NIH HHS / DC / DC006070-02; United States / NIDCD NIH HHS / DC / R01 DC006070; United States / NIDCD NIH HHS / DC / R01 DC006070-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isoenzymes; 0 / Receptors, G-Protein-Coupled; 0 / TRPM Cation Channels; 0 / Trpm5 protein, mouse; 0 / taste receptors, type 2; 147979-21-3 / gustducin; EC 3.1.4.- / Type C Phospholipases; EC 3.1.4.11 / Phospholipase C beta; EC 3.6.1.- / GTP-Binding Proteins; EC 3.6.1.- / Transducin; G34N38R2N1 / Bromodeoxyuridine
  • [Other-IDs] NLM/ NIHMS39474; NLM/ PMC2262107
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38. Kameda Y: Dual origins of the mouse carotid body revealed by targeted disruption of Hoxa3 and Mash1. Adv Exp Med Biol; 2006;580:93-7; discussion 351-9
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  • [Title] Dual origins of the mouse carotid body revealed by targeted disruption of Hoxa3 and Mash1.
  • [MeSH-major] Basic Helix-Loop-Helix Transcription Factors / deficiency. Carotid Body / embryology. Carotid Body / metabolism. Homeodomain Proteins / metabolism

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  • (PMID = 16683703.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ascl1 protein, mouse; 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Homeodomain Proteins; 0 / Hoxa3 protein, mouse; 0 / Neuropeptide Y; 333DO1RDJY / Serotonin; EC 1.14.16.2 / Tyrosine 3-Monooxygenase
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39. Naniwadekar MR, Jagtap SV, Kshirsagar AY, Shinagare SA, Tata HR, Sahoo K: Fine needle aspiration diagnosis of carotid body tumor in a case of multiple paragangliomas presenting with facial palsy: a case report. Acta Cytol; 2010 Jul-Aug;54(4):635-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration diagnosis of carotid body tumor in a case of multiple paragangliomas presenting with facial palsy: a case report.
  • BACKGROUND: Carotid body tumors (CBTs) constitute the most common extraadrenal paragangliomas.
  • The main differential diagnosis is a thyroid neoplasm.
  • The location of the mass in the lateral neck with prolonged history, hemorrhagic FNA and cytologic features resembling the endocrine neoplasm help in arriving at a suggestive diagnosis of paraganglioma.
  • A diagnosis of CBT was suggested.
  • It was supplemented by additional noninvasive methods, such as ultrasonography of the neck region with color Doppler, computed tomography and magnetic resonance imaging of the brain, which also revealed a neoplasm suggestive of carotid body tumor in the right side of the neck and neoplastic lesion in the left cerebellopontine angle, suggestive of paraganglioma.
  • CONCLUSION: FNA, with the other noninvasive radiologic investigations, plays an important role in the diagnosis of CBT.
  • We present this case of multiple paragangliomas for its unusual presentation and FNA diagnosis.
  • [MeSH-major] Brain Neoplasms / diagnosis. Carotid Body Tumor / diagnosis. Facial Paralysis / diagnosis. Head and Neck Neoplasms / diagnosis


40. Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE: Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes. Clin Exp Pharmacol Physiol; 2005 May-Jun;32(5-6):447-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes.
  • Enhanced hypoxic-sensing ability of the carotid bodies and the ensuing reflex activation of the sympathetic nervous system have been suggested to play a critical role in cardiorespiratory alterations resulting from recurrent apnoeas.
  • 2. The purpose of the present review is to highlight recent studies demonstrating the effects of IH on carotid body sensory activity and its consequences on sympathetic activation in a rodent model of chronic IH.
  • Adult rats exposed to chronic IH (15 s of 5% O(2) followed by 5 min of 21% O(2), nine episodes per h, 8 h/day for 10 days) exhibited selective enhancement of carotid body sensory response to hypoxia.
  • In addition, chronic IH induced a novel form of sensory plasticity in the carotid body, manifested as sensory long-term facilitation (LTF).
  • Functional changes in the carotid body occurred in the absence of morphological changes in the chemoreceptor tissue.
  • Bilateral sectioning of the sinus nerves abolished these responses, suggesting chronic IH-induced alterations in carotid body sensitivity contribute to LTF in SNA and the subsequent cardiovascular alterations.
  • [MeSH-major] Blood Pressure / physiology. Carotid Body / physiology. Hypoxia, Brain / physiopathology

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  • (PMID = 15854156.001).
  • [ISSN] 0305-1870
  • [Journal-full-title] Clinical and experimental pharmacology & physiology
  • [ISO-abbreviation] Clin. Exp. Pharmacol. Physiol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL-25830; United States / NHLBI NIH HHS / HL / HL-66448
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] Australia
  • [Number-of-references] 11
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41. Ural A, Kutluhan A, Yurttaş V, Berçin S, Onursever A: [Vascular leiomyoma mimicking a carotid body tumor]. Kulak Burun Bogaz Ihtis Derg; 2008 Sep-Oct;18(5):316-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Vascular leiomyoma mimicking a carotid body tumor].
  • Angiography showed a mass in the carotid bifurcation.
  • It was not extensively vascularized, but displaced the internal and external carotid arteries.
  • Histopathologic diagnosis was vascular leiomyoma.
  • [MeSH-major] Angiomyoma / diagnosis. Carotid Body Tumor / diagnosis. Head and Neck Neoplasms / diagnosis
  • [MeSH-minor] Adult. Angiography. Diagnosis, Differential. Female. Humans

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  • (PMID = 19155679.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Turkey
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42. Baby SM, Roy A, Lahiri S: Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells. Histochem Cell Biol; 2005 Jul;124(1):69-76
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  • [Title] Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells.
  • Earlier, we have reported that in carotid body (CB), the peripheral oxygen sensing organ, HIF-1alpha is up-regulated during hypoxia.
  • To test this hypothesis in the CB glomus cells, we studied the effect of mitochondrial electron transport chain (ETC) inhibitors: rotenone (complex I; 1 microM), malonate (complex II; 0.5 M), antimycin A (complex III; 1 microg/ml), sodium azide (complex IV; 5 mM), and uncoupler of oxidative phosphorylation: carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP; 1 mM) on HIF-1alpha expression during normoxia and hypoxia.
  • Inhibitors and uncoupler of mitochondrial ETC abrogated hypoxia-induced HIF-1alpha expression in isolated glomus cells significantly (P < 0.001).
  • [MeSH-major] Carotid Body / metabolism. Mitochondria / metabolism

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  • [Cites] Nature. 1999 May 20;399(6733):271-5 [10353251.001]
  • [Cites] Science. 2003 Dec 12;302(5652):1975-8 [14671307.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1981 Aug;51(2):438-46 [7263450.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2002 Nov;283(5):L922-31 [12376345.001]
  • [Cites] J Biol Chem. 2000 Nov 17;275(46):35863-7 [10961998.001]
  • [Cites] J Physiol. 1998 Dec 15;513 ( Pt 3):819-33 [9824720.001]
  • [Cites] J Physiol. 1992 May;450:33-61 [1432712.001]
  • [Cites] Blood. 2001 Jul 15;98(2):296-302 [11435296.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):821-6 [11792862.001]
  • [Cites] Science. 2001 Apr 20;292(5516):464-8 [11292862.001]
  • [Cites] J Appl Physiol (1985). 2002 Dec;93(6):1987-98 [12391083.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2001 Jul;281(1):L202-8 [11404263.001]
  • [Cites] Respir Physiol Neurobiol. 2002 Aug 1;131(3):175-87 [12126919.001]
  • [Cites] Cell. 2001 Oct 5;107(1):43-54 [11595184.001]
  • [Cites] Hum Genet. 2003 Aug;113(3):228-37 [12811540.001]
  • [Cites] J Physiol. 2004 Apr 1;556(Pt 1):175-91 [14724184.001]
  • [Cites] Neurosci Lett. 2004 Jun 17;363(3):229-32 [15182949.001]
  • [Cites] Respir Physiol Neurobiol. 2004 Jul 20;141(2):115-23 [15239962.001]
  • [Cites] J Biol Chem. 2001 Jun 22;276(25):21995-8 [11342528.001]
  • [Cites] J Physiol. 2003 May 1;548(Pt 3):789-800 [12626666.001]
  • [Cites] Histochem Cell Biol. 2003 Nov;120(5):343-52 [14600837.001]
  • [Cites] Biochem Pharmacol. 2000 Jan 1;59(1):47-53 [10605934.001]
  • [Cites] J Appl Physiol (1985). 1994 Mar;76(3):1317-23 [8005877.001]
  • [Cites] Int J Biochem Cell Biol. 2001 Aug;33(8):755-74 [11404180.001]
  • [Cites] Am J Physiol. 1982 Mar;242(3):C200-6 [6801997.001]
  • [Cites] J Biol Chem. 2000 Aug 18;275(33):25130-8 [10833514.001]
  • [Cites] Biochem J. 2003 Dec 1;376(Pt 2):537-44 [14531732.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7987-92 [9653127.001]
  • [Cites] Science. 2002 Feb 1;295(5556):858-61 [11823643.001]
  • (PMID = 16034640.001).
  • [ISSN] 0948-6143
  • [Journal-full-title] Histochemistry and cell biology
  • [ISO-abbreviation] Histochem. Cell Biol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R 37-HL-43413-15; United States / NHLBI NIH HHS / HL / T32 HL-07207-30
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ion Channels; S88TT14065 / Oxygen
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43. Leaf DE, Goldfarb DS: Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness. J Appl Physiol (1985); 2007 Apr;102(4):1313-22
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  • Such factors include not only metabolic acidosis resulting from renal CA inhibition but also improvements in ventilation from tissue respiratory acidosis, improvements in sleep quality from carotid body CA inhibition, and effects of diuresis.

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  • [CommentIn] J Appl Physiol (1985). 2007 Apr;102(4):1305-7 [17194729.001]
  • (PMID = 17023566.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Editorial; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbonic Anhydrase Inhibitors; O3FX965V0I / Acetazolamide; S88TT14065 / Oxygen
  • [Number-of-references] 118
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44. Conde SV, Monteiro EC: Profiles for ATP and adenosine release at the carotid body in response to O2 concentrations. Adv Exp Med Biol; 2006;580:179-84; discussion 351-9
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  • [Title] Profiles for ATP and adenosine release at the carotid body in response to O2 concentrations.
  • [MeSH-major] Adenosine / metabolism. Adenosine Triphosphate / metabolism. Carotid Body / metabolism. Oxygen / metabolism

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  • (PMID = 16683716.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 8L70Q75FXE / Adenosine Triphosphate; K72T3FS567 / Adenosine; S88TT14065 / Oxygen
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45. Caceres AI, Obeso A, Gonzalez C, Rocher A: Molecular identification and functional role of voltage-gated sodium channels in rat carotid body chemoreceptor cells. Regulation of expression by chronic hypoxia in vivo. J Neurochem; 2007 Jul;102(1):231-45
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  • [Title] Molecular identification and functional role of voltage-gated sodium channels in rat carotid body chemoreceptor cells. Regulation of expression by chronic hypoxia in vivo.
  • We have assessed the expression, molecular identification and functional role of Na+ channels (Na(v)) in carotid bodies (CB) obtained from normoxic and chronically hypoxic adult rats.
  • [MeSH-major] Anoxia / metabolism. Carotid Body / metabolism. Chemoreceptor Cells / metabolism. Sodium Channels / metabolism

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  • (PMID = 17564680.001).
  • [ISSN] 0022-3042
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Catecholamines; 0 / Sodium Channels; 63231-63-0 / RNA; EC 1.14.16.2 / Tyrosine 3-Monooxygenase
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46. Donnelly DF: Spontaneous action potential generation due to persistent sodium channel currents in simulated carotid body afferent fibers. J Appl Physiol (1985); 2008 May;104(5):1394-401
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  • [Title] Spontaneous action potential generation due to persistent sodium channel currents in simulated carotid body afferent fibers.
  • The mechanism by which action potentials (APs) are generated in afferent nerve fibers in the carotid body is unknown, but it is generally speculated to be release of an excitatory transmitter and synaptic depolarizing events.
  • While the density of Na(+) channels was kept constant, spontaneous APs arose in nerve terminals as the axonal diameter was reduced to that in rat carotid body.
  • [MeSH-major] Action Potentials / physiology. Carotid Body / physiology. Neurons, Afferent / physiology. Sodium Channels / physiology

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  • (PMID = 18309093.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL 073500
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sodium Channels
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47. Ward SA: Ventilatory control in humans: constraints and limitations. Exp Physiol; 2007 Mar;92(2):357-66
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  • While ventilatory control models have traditionally included proportional feedback (central and carotid chemosensory) and feedforward (central and peripheral neurogenic) elements, the mechanisms involved remain unclear.
  • Above (thetaL), PaCO2 is driven down to constrain the fall of arterial pH by a compensatory hyperventilation, probably of carotid body origin.

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  • (PMID = 17234715.001).
  • [ISSN] 0958-0670
  • [Journal-full-title] Experimental physiology
  • [ISO-abbreviation] Exp. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide; 33X04XA5AT / Lactic Acid
  • [Number-of-references] 54
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48. Kollert M, Minovi A, Mangold R, Hendus J, Draf W, Bockmühl U: [Paraganglioma of the head and neck--tumor control, functional results and quality of life]. Laryngorhinootologie; 2006 Sep;85(9):649-56
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  • [Title] [Paraganglioma of the head and neck--tumor control, functional results and quality of life].
  • [Transliterated title] Paragangliome des Kopf-Hals-Bereiches--Tumorkontrolle, funktionelle Ergebnisse und Lebensqualität nach Operation.
  • These patients had follow-up examination within a clinical trial considering tumor control, functional results and for the first time neuropsychologically evaluated postoperative quality of life.
  • RESULTS: Among the 94 PG there were 19 carotid body (GCP), 12 vagal nerve (GVP) and 63 jugular-tympanal paragangliomas (JTP).
  • In 68 patients (78.1 %), the tumor could be removed completely.
  • One recurrent tumor was radiated and 3 others are under observation without showing growth tendencies.
  • CONCLUSION: Whereas complete tumor resection of GCP and JTP types A and B is almost ever possible without cranial nerve palsies, surgery of GVP and advanced JTP causes often severe functional deficits.
  • Nevertheless, advanced PG require an individualized therapeutic regime also including radiation and observation of tumor growth.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carotid Body Tumor / surgery. Combined Modality Therapy. Cranial Nerve Neoplasms / surgery. Female. Follow-Up Studies. Glomus Jugulare Tumor / surgery. Glomus Tympanicum Tumor / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Time Factors. Treatment Outcome. Vagus Nerve Diseases / surgery

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  • (PMID = 16612748.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Clinical Trial; Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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49. Kääb S, Miguel-Velado E, López-López JR, Pérez-García MT: Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body. J Physiol; 2005 Jul 15;566(Pt 2):395-408
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  • [Title] Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body.
  • The carotid body (CB) chemoreceptors participate in the ventilatory responses to acute and chronic hypoxia (CH).
  • [MeSH-major] Anoxia / metabolism. Carotid Body / physiology. Down-Regulation / physiology. Oxygen / physiology. Potassium Channels, Voltage-Gated / metabolism

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  • [Cites] J Neurochem. 1992 Apr;58(4):1538-46 [1347783.001]
  • [Cites] J Gen Physiol. 1989 May;93(5):979-99 [2544656.001]
  • [Cites] Ann N Y Acad Sci. 1999 Apr 30;868:233-85 [10414301.001]
  • [Cites] Circ Res. 2000 Mar 17;86(5):490-1 [10720407.001]
  • [Cites] J Neurosci. 2000 Aug 1;20(15):5689-95 [10908607.001]
  • [Cites] Respir Physiol. 2000 Jul;121(2-3):237-46 [10963778.001]
  • [Cites] J Gen Physiol. 1992 Sep;100(3):427-55 [1431804.001]
  • [Cites] J Physiol. 1993 Jan;460:15-32 [8387583.001]
  • [Cites] Nature. 1993 Sep 9;365(6442):153-5 [8371757.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):295-9 [7529413.001]
  • [Cites] J Neurosci. 1995 Mar;15(3 Pt 2):2192-202 [7891161.001]
  • [Cites] FASEB J. 1995 Feb;9(2):183-9 [7781921.001]
  • [Cites] J Membr Biol. 1995 Mar;144(1):1-9 [7595937.001]
  • [Cites] J Physiol. 1997 Jul 15;502 ( Pt 2):293-305 [9263911.001]
  • [Cites] J Biol Chem. 1998 Mar 20;273(12):6744-9 [9506974.001]
  • [Cites] Brain Res. 1998 Nov 16;811(1-2):79-87 [9804901.001]
  • [Cites] J Physiol. 1999 Jan 15;514 ( Pt 2):483-91 [9852329.001]
  • [Cites] Anal Biochem. 1999 May 15;270(1):41-9 [10328763.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2001 Apr;280(4):L801-12 [11238022.001]
  • [Cites] Comp Biochem Physiol B Biochem Mol Biol. 2001 Feb;128(2):187-204 [11207433.001]
  • [Cites] Eur Respir J. 2001 Jul;18(1):221-7 [11510795.001]
  • [Cites] Respir Res. 2001;2(3):145-9 [11686878.001]
  • [Cites] Neurosci Lett. 2002 Jan 25;318(2):69-72 [11796188.001]
  • [Cites] Methods. 2001 Dec;25(4):402-8 [11846609.001]
  • [Cites] J Physiol. 2002 Jul 15;542(Pt 2):369-82 [12122138.001]
  • [Cites] Microsc Res Tech. 2002 Nov 1;59(3):168-77 [12384961.001]
  • [Cites] Circulation. 2003 Apr 22;107(15):2037-44 [12695303.001]
  • [Cites] J Biol Chem. 2003 Jun 20;278(25):22316-24 [12679337.001]
  • [Cites] Adv Exp Med Biol. 2003;536:33-9 [14635646.001]
  • [Cites] J Biol Chem. 2003 Dec 19;278(51):51422-32 [14522958.001]
  • [Cites] J Physiol. 2004 Jun 1;557(Pt 2):457-71 [15034123.001]
  • [Cites] J Neurochem. 1979 Sep;33(3):713-9 [39119.001]
  • [Cites] Pflugers Arch. 1981 Aug;391(2):85-100 [6270629.001]
  • [Cites] J Appl Physiol (1985). 1986 Mar;60(3):1003-10 [3082845.001]
  • [Cites] Science. 1988 Jul 29;241(4865):580-2 [2456613.001]
  • [Cites] J Gen Physiol. 1989 May;93(5):1001-15 [2738574.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9469-73 [1329096.001]
  • (PMID = 15890707.001).
  • [ISSN] 0022-3751
  • [Journal-full-title] The Journal of physiology
  • [ISO-abbreviation] J. Physiol. (Lond.)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Potassium Channels, Voltage-Gated; 0 / RNA, Messenger; S88TT14065 / Oxygen
  • [Other-IDs] NLM/ PMC1464757
  •  go-up   go-down


50. Yamamoto Y, Taniguchi K: Expression of tandem P domain K+ channel, TREK-1, in the rat carotid body. J Histochem Cytochem; 2006 Apr;54(4):467-72
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  • [Title] Expression of tandem P domain K+ channel, TREK-1, in the rat carotid body.
  • To examine the distribution of TREK-1 in the rat carotid body, we performed RT-PCR for mRNA expression and in situ hybridization and immunohistochemistry for tissue distribution of TREK-1.
  • RT-PCR detected mRNA expression of TREK-1 in the carotid body.
  • Furthermore, in situ hybridization revealed the localization of TREK-1 mRNA in the glomus cells.
  • TREK-1 immunoreactivity was mainly distributed in the glomus cells and nerve fibers in the carotid body.
  • TREK-1 may modulate potassium current of glomus cells and/or afferent nerve endings in the rat carotid body.
  • [MeSH-major] Carotid Body / metabolism. Potassium Channels, Tandem Pore Domain / biosynthesis

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  • (PMID = 16344329.001).
  • [ISSN] 0022-1554
  • [Journal-full-title] The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • [ISO-abbreviation] J. Histochem. Cytochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Potassium Channels, Tandem Pore Domain; 0 / RNA, Messenger; 0 / potassium channel protein TREK-1
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51. Paris J, Facon F, Thomassin JM, Zanaret M: Cervical paragangliomas: neurovascular surgical risk and therapeutic management. Eur Arch Otorhinolaryngol; 2006 Sep;263(9):860-5
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  • Paragangliomas of the neck region arise most commonly in the carotid and vagal bodies.
  • There were 29 carotid body tumors and 11 vagal body tumors.
  • A vascular repair procedure was performed in 10% and always occurred in carotid body tumors including the malignant one.
  • Paralysis of vagus nerve was reported in 11 cases (27.5%), nine of whom were patients with vagal body tumors.
  • Early management of patients prevents progressive neurological deficit due to an enlarging tumor mass and minimizes neurovascular complications.
  • [MeSH-minor] Adult. Aortic Bodies / surgery. Carotid Body / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nervous System Diseases / etiology. Perioperative Care. Retrospective Studies. Risk Factors. Sex Factors. Treatment Outcome

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  • [Cites] Mayo Clin Proc. 1988 Apr;63(4):348-52 [3352318.001]
  • [Cites] Laryngoscope. 2000 Aug;110(8):1346-8 [10942138.001]
  • [Cites] Int Surg. 1997 Oct-Dec;82(4):394-7 [9412839.001]
  • [Cites] Hum Pathol. 1998 Oct;29(10):1045-9 [9781639.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1989 Jan;98(1 Pt 1):21-6 [2535921.001]
  • [Cites] Arch Surg. 1992 Dec;127(12):1441-5 [1365691.001]
  • [Cites] Br J Surg. 1977 Dec;64(12):885-9 [588988.001]
  • [Cites] Otolaryngol Head Neck Surg. 2000 Apr;122(4):482-7 [10740165.001]
  • [Cites] J Chir (Paris). 1995 Jun-Jul;132(6-7):287-94 [7499450.001]
  • [Cites] J Cardiovasc Surg (Torino). 1999 Oct;40(5):691-4 [10597004.001]
  • [Cites] Laryngoscope. 1986 May;96(5):533-6 [3010016.001]
  • [Cites] Rev Laryngol Otol Rhinol (Bord). 1989;110(2):213-7 [2551028.001]
  • [Cites] Head Neck. 2003 Feb;25(2):146-51 [12509798.001]
  • [Cites] Laryngoscope. 1997 Jun;107(6):821-6 [9185740.001]
  • [Cites] J Neurosurg. 1986 Mar;64(3):377-85 [3950716.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1992 Aug;101(8):635-42 [1497267.001]
  • [Cites] Laryngoscope. 1987 Nov;97(11):1331-5 [2823034.001]
  • [Cites] Br J Surg. 1985 Nov;72(11):903-5 [2998535.001]
  • [Cites] Am J Surg. 1996 Aug;172(2):196-9 [8795531.001]
  • [Cites] Am J Hum Genet. 1997 Jan;60(1):121-32 [8981955.001]
  • [Cites] Otolaryngol Head Neck Surg. 1990 Apr;102(4):382-90 [2113266.001]
  • [Cites] Laryngoscope. 1994 Apr;104(4):440-5 [8164483.001]
  • [Cites] J Laryngol Otol. 2001 Jun;115(6):467-74 [11429070.001]
  • [Cites] Br J Surg. 1986 Jan;73(1):14-6 [3947866.001]
  • [Cites] Hum Pathol. 1979 Mar;10(2):191-218 [422190.001]
  • [Cites] J Vasc Surg. 1988 Feb;7(2):284-91 [2828696.001]
  • [Cites] Am J Surg. 1971 Dec;122(6):732-9 [5127724.001]
  • [Cites] J Laryngol Otol. 1992 Jun;106(6):538-43 [1320657.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1986 Dec;12(12):2175-8 [3025140.001]
  • (PMID = 16823560.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


52. Kollert M, Minovi AA, Draf W, Bockmühl U: Cervical paragangliomas-tumor control and long-term functional results after surgery. Skull Base; 2006 Nov;16(4):185-91
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  • [Title] Cervical paragangliomas-tumor control and long-term functional results after surgery.
  • Of these, 16 were carotid body tumors and 11 were vagal paragangliomas.
  • RESULTS: There were 13 solitary tumors of which 5 were carotid body tumors and 8 vagal paragangliomas.
  • The incidence of associated multiple tumors was 64.3% for carotid body tumors and 38.5% for vagal paragangliomas.
  • Complete tumor resection was achieved in all but 1 patient in whom a small intradural residual vagal paraganglioma had to be left.
  • The internal carotid artery was preserved in all carotid body tumor resections.
  • Lower cranial nerve deficits were sustained in 1 carotid body tumor resection only, but in all cases with multiple tumors.
  • CONCLUSIONS: Even in large head and neck paragangliomas surgical treatment provides excellent tumor control with low postoperative morbidity.

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  • [Cites] Head Neck. 2002 May;24(5):423-31 [12001071.001]
  • [Cites] Head Neck. 2001 May;23(5):363-71 [11295809.001]
  • [Cites] Cancer. 2002 Feb 1;94(3):730-7 [11857306.001]
  • [Cites] Otolaryngol Clin North Am. 2001 Oct;34(5):925-39, vi [11557447.001]
  • [Cites] J Laryngol Otol. 2001 Jun;115(6):467-74 [11429070.001]
  • [Cites] J Laryngol Otol. 1993 Jun;107(6):538-42 [8345303.001]
  • [Cites] Head Neck. 1998 Oct;20(7):609-13 [9744460.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1992;22(5):919-24 [1313406.001]
  • [Cites] Am J Otol. 1993 Jul;14(4):398-402 [8238279.001]
  • [Cites] Laryngoscope. 1994 Apr;104(4):440-5 [8164483.001]
  • [Cites] Laryngoscope. 1994 Dec;104(12):1461-5 [7990634.001]
  • [Cites] Laryngoscope. 1995 Mar;105(3 Pt 1):231-5 [7877408.001]
  • [Cites] Hum Genet. 1982;60(4):305-9 [6286462.001]
  • [Cites] Laryngoscope. 1981 Jun;91(6):988-96 [6264239.001]
  • [Cites] Am J Surg. 1971 Dec;122(6):732-9 [5127724.001]
  • [Cites] Hum Pathol. 1979 Mar;10(2):191-218 [422190.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1989 Jan;98(1 Pt 1):21-6 [2535921.001]
  • [Cites] Otolaryngol Head Neck Surg. 1990 Apr;102(4):382-90 [2113266.001]
  • [Cites] Head Neck. 2004 Dec;26(12):1058-63 [15459923.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1998 Oct;124(10):1133-40 [9776192.001]
  • [Cites] Otolaryngol Head Neck Surg. 2000 Sep;123(3):202-6 [10964291.001]
  • [Cites] Ann Vasc Surg. 2002 May;16(3):331-8 [11957009.001]
  • (PMID = 17471317.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1766458
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53. Burlon DC, Jordan HL, Wyatt CN: Presynaptic regulation of isolated neonatal rat carotid body type I cells by histamine. Respir Physiol Neurobiol; 2009 Sep 30;168(3):218-23
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  • [Title] Presynaptic regulation of isolated neonatal rat carotid body type I cells by histamine.
  • The type I cells are the chemoreceptive elements of the carotid bodies and are critical in defining the ventilatory response to hypoxia and hypercapnia.
  • Recent evidence has suggested that histamine is released by the carotid body in response to hypoxia and acts as an excitatory neurotransmitter.
  • Thus activation of histamine receptors on type I cells is unlikely to provide a presynaptic positive feedback mechanism during chemotransduction and any excitatory role attributed to the actions of histamine is likely to come from a postsynaptic effect on the carotid sinus nerve (CSN).
  • [MeSH-major] Carotid Body / cytology. Histamine / pharmacology. Neurons / metabolism. Presynaptic Terminals / drug effects. Receptors, Histamine / metabolism

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  • (PMID = 19596465.001).
  • [ISSN] 1878-1519
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Histamine Agonists; 0 / Muscarinic Agonists; 0 / Receptors, Histamine; 0W5ETF9M2K / Methacholine Chloride; 820484N8I3 / Histamine; SY7Q814VUP / Calcium
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54. Schiavi F, Boedeker CC, Bausch B, Peçzkowska M, Gomez CF, Strassburg T, Pawlu C, Buchta M, Salzmann M, Hoffmann MM, Berlis A, Brink I, Cybulla M, Muresan M, Walter MA, Forrer F, Välimäki M, Kawecki A, Szutkowski Z, Schipper J, Walz MK, Pigny P, Bauters C, Willet-Brozick JE, Baysal BE, Januszewicz A, Eng C, Opocher G, Neumann HP, European-American Paraganglioma Study Group: Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. JAMA; 2005 Oct 26;294(16):2057-63
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  • Location, number of tumors, malignancy, and age were different: more carotid body tumors were found in SDHC (13/22 [59%]) than in sporadic HNPs (29/90 [32%], P = .03), as well as fewer instances of multiple tumors in SDHC (2/22) than in SDHD (24/42; P<.001), 0 malignant tumors in SDHC vs 6/15 in SDHB (P = .002), and younger age at diagnosis in SDHC than in sporadic HNPs (45 vs 52 years; P = .03).
  • Head and neck paragangliomas associated with SDHC mutations are virtually exclusively benign and seldom multifocal.

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  • [CommentIn] JAMA. 2006 Feb 8;295(6):625; author reply 625 [16467230.001]
  • [ErratumIn] JAMA. 2006 Feb 8;295(6):628
  • (PMID = 16249420.001).
  • [ISSN] 1538-3598
  • [Journal-full-title] JAMA
  • [ISO-abbreviation] JAMA
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / R01HD39058-04; United States / NICHD NIH HHS / HD / R01HD39058-04S1
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iron-Sulfur Proteins; 0 / Membrane Proteins; 0 / Protein Subunits; 0 / SDHC protein, human; 0 / SDHD protein, human; EC 1.3.5.1 / SDHB protein, human; EC 1.3.99.1 / Succinate Dehydrogenase
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55. Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Castillo G: Altitude adaptation through hematocrit changes. J Physiol Pharmacol; 2007 Nov;58 Suppl 5(Pt 2):811-8
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  • Immediately upon ascent to high altitude, the carotid body senses the lowering of the arterial oxygen partial pressure due to a diminished barometric pressure.

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  • (PMID = 18204195.001).
  • [ISSN] 0867-5910
  • [Journal-full-title] Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
  • [ISO-abbreviation] J. Physiol. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] S88TT14065 / Oxygen
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56. Dumont FS, Kinkead R: Neonatal stress and attenuation of the hypercapnic ventilatory response in adult male rats: the role of carotid chemoreceptors and baroreceptors. Am J Physiol Regul Integr Comp Physiol; 2010 Nov;299(5):R1279-89
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  • [Title] Neonatal stress and attenuation of the hypercapnic ventilatory response in adult male rats: the role of carotid chemoreceptors and baroreceptors.
  • To address this issue, we first tested the hypothesis that carotid bodies contribute to NMS-related attenuation of the HCVR by using carotid sinus nerve section or Fi(O(2)) manipulation to maintain Pa(O(2)) constant (iso-oxic) during hypercapnic hyperpnea.
  • We conclude that NMS-related changes in carotid body sensitivity to chemical stimuli and/or its central integration is a key mechanism in the attenuation of HCVR by NMS.
  • [MeSH-major] Anxiety, Separation / physiopathology. Baroreflex. Carotid Sinus / innervation. Chemoreceptor Cells / metabolism. Hypercapnia / physiopathology. Maternal Deprivation. Pressoreceptors / physiopathology. Pulmonary Ventilation

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  • (PMID = 20811006.001).
  • [ISSN] 1522-1490
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vasoconstrictor Agents; 0 / Vasodilator Agents; S88TT14065 / Oxygen
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57. Feng J, Chen BY, Cui LY, Wang BL, Liu CX, Chen PF, Guo MN, Dong LX, Li S: [Carotid body inflammation and carotid sinus nerve afferent activity after intermittent hypoxia exposure of various frequencies in rabbits]. Zhonghua Jie He He Hu Xi Za Zhi; 2008 Sep;31(9):670-4
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  • [Title] [Carotid body inflammation and carotid sinus nerve afferent activity after intermittent hypoxia exposure of various frequencies in rabbits].
  • OBJECTIVE: To explore the inflammatory reactions, endothelin level and carotid sinus nerve (CSN) afferent activity of carotid body (CB) after intermittent hypoxia/reoxygenation (IH/ROX) exposure of various frequencies in rabbits.
  • After anesthetization, the right carotid artery and CSN were cleared of surrounding tissues without touching the right CB and the left carotid region.
  • Then the right common carotid artery was exposed, cannulated to distal part and its proximal part was ligated.
  • Alternatively perfusion (2 ml/min) of equilibrated perfusate bubbled with normoxia or hypoxia gas mixtures formed IH/ROX cycles in right carotid common artery, simulating the pattern of hypoxic episodes seen in obstructive sleep apnea, or with continuously perfusing hypoxia perfusate to form continuous hypoxia (CH) modes.
  • [MeSH-major] Afferent Pathways / metabolism. Anoxia / metabolism. Anoxia / pathology. Carotid Body / pathology. Inflammation
  • [MeSH-minor] Animals. Carotid Sinus / innervation. Male. Rabbits

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  • (PMID = 19080567.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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58. Powell FL, Fu Z: HIF-1 and ventilatory acclimatization to chronic hypoxia. Respir Physiol Neurobiol; 2008 Dec 10;164(1-2):282-7
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  • Ventilatory acclimatization to hypoxia (VAH) is a time-dependent increase in ventilation and ventilatory O2-sensitivity that involves plasticity in carotid body chemoreceptors and CNS respiratory centers.
  • Studies using transgenic mice show HIF-1alpha expression in the carotid bodies and CNS with chronic sustained and intermittent hypoxia is important for VAH.

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  • [Cites] Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):821-6 [11792862.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15306-11 [11742077.001]
  • [Cites] Pflugers Arch. 2002 Feb;443(4):565-73 [11907823.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1314-23 [12003788.001]
  • [Cites] Respir Physiol Neurobiol. 2003 May 30;135(2-3):133-44 [12809614.001]
  • [Cites] FASEB J. 2003 Aug;17(11):1541-3 [12824304.001]
  • [Cites] Annu Rev Neurosci. 2003;26:105-31 [14527267.001]
  • [Cites] Brain Res. 2003 Nov 7;989(2):231-7 [14556945.001]
  • [Cites] Nat Neurosci. 2004 Jan;7(1):48-55 [14699417.001]
  • [Cites] Adv Exp Med Biol. 2003;543:323-30 [14713131.001]
  • [Cites] J Appl Physiol (1985). 2004 Mar;96(3):1236-42; discussion 1196 [14660510.001]
  • [Cites] J Appl Physiol (1985). 2004 Mar;96(3):1187-95; discussion 1170-2 [14766769.001]
  • [Cites] Biol Chem. 2004 Mar-Apr;385(3-4):217-21 [15134334.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Jul 23;320(2):514-22 [15219859.001]
  • [Cites] Physiol Rev. 1982 Jan;62(1):262-346 [6798585.001]
  • [Cites] J Biol Chem. 1994 Jan 7;269(1):760-4 [7903970.001]
  • [Cites] J Appl Physiol (1985). 1994 Sep;77(3):1451-9 [7836152.001]
  • [Cites] J Physiol. 1995 Jul 15;486 ( Pt 2):495-504 [7473213.001]
  • [Cites] Am J Physiol. 1996 Jun;270(6 Pt 2):R1279-86 [8764295.001]
  • [Cites] Kidney Int. 1997 Feb;51(2):527-35 [9027733.001]
  • [Cites] Brain Res Mol Brain Res. 1996 Dec 31;43(1-2):341-6 [9037552.001]
  • [Cites] Am J Obstet Gynecol. 1998 Mar;178(3):527-34 [9539521.001]
  • [Cites] Biochem Biophys Res Commun. 1998 Apr 28;245(3):894-9 [9588211.001]
  • [Cites] EMBO J. 1998 Jun 1;17(11):3005-15 [9606183.001]
  • [Cites] Respir Physiol. 1998 May;112(2):123-34 [9716296.001]
  • [Cites] Blood. 1998 Oct 1;92(7):2260-8 [9746763.001]
  • [Cites] Curr Opin Genet Dev. 1998 Oct;8(5):588-94 [9794818.001]
  • [Cites] J Appl Physiol (1985). 1999 Aug;87(2):817-23 [10444644.001]
  • [Cites] J Cereb Blood Flow Metab. 2005 Feb;25(2):281-90 [15678129.001]
  • [Cites] J Biol Chem. 2005 Feb 11;280(6):4321-8 [15569687.001]
  • [Cites] IUBMB Life. 2004 Nov-Dec;56(11-12):681-7 [15804832.001]
  • [Cites] J Neurosci. 2005 Apr 20;25(16):4099-107 [15843612.001]
  • [Cites] Pediatr Res. 2005 Jul;58(1):53-7 [15879294.001]
  • [Cites] Pflugers Arch. 2005 Sep;450(6):363-71 [16007431.001]
  • [Cites] J Physiol. 2005 Oct 15;568(Pt 2):559-71 [16051624.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Dec 9;338(1):568-77 [16183036.001]
  • [Cites] J Clin Invest. 2005 Nov;115(11):3128-39 [16276418.001]
  • [Cites] J Physiol. 2006 Dec 1;577(Pt 2):705-16 [16973705.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R403-14 [16973934.001]
  • [Cites] Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2301-6 [17284606.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R829-36 [17475674.001]
  • [Cites] J Physiol. 2007 Aug 15;583(Pt 1):329-36 [17584830.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1702-10 [17652365.001]
  • [Cites] J Appl Physiol (1985). 2007 Nov;103(5):1506-12 [17690195.001]
  • [Cites] Methods Enzymol. 2007;435:479-92 [17998070.001]
  • [Cites] Histol Histopathol. 2008 Mar;23(3):271-80 [18072084.001]
  • [Cites] Nat Genet. 2008 Feb;40(2):170-80 [18176562.001]
  • [Cites] Proc Biol Sci. 2008 Apr 7;275(1636):751-8 [18089537.001]
  • [Cites] Cell Death Differ. 2008 Apr;15(4):621-7 [18259201.001]
  • [Cites] Exp Cell Res. 2008 Jun 10;314(10):2016-27 [18420194.001]
  • [Cites] Histochem Cell Biol. 2008 Sep;130(3):549-59 [18446360.001]
  • [Cites] J Cereb Blood Flow Metab. 2008 Sep;28(9):1530-42 [18478024.001]
  • [Cites] Annu Rev Cell Dev Biol. 1999;15:551-78 [10611972.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2000 Aug;279(2):R515-21 [10938240.001]
  • [Cites] Respir Physiol. 2000 Jul;121(2-3):87-100 [10963767.001]
  • [Cites] Respir Physiol. 2000 Jul;121(2-3):237-46 [10963778.001]
  • [Cites] Respir Physiol. 2000 Sep;122(2-3):271-84 [10967350.001]
  • [Cites] J Appl Physiol (1985). 2001 Jul;91(1):379-85 [11408455.001]
  • [Cites] Eur J Neurosci. 2001 Dec;14(12):1981-91 [11860493.001]
  • (PMID = 18708172.001).
  • [ISSN] 1569-9048
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / HL081823-03; United States / NHLBI NIH HHS / HL / R01 HL081823; United States / NHLBI NIH HHS / HL / 1R01HL081823; United States / NHLBI NIH HHS / HL / R01 HL081823-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Hypoxia-Inducible Factor 1
  • [Number-of-references] 61
  • [Other-IDs] NLM/ NIHMS78658; NLM/ PMC2700119
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59. Pozdzik M, Zajac D, Zasada I, Czarnocki Z, Matysiak Z, Mazzatenta A, Pokorski M: Absence of bioactivity of lipid derivatives of serotonin. Eur J Med Res; 2010 Nov 4;15 Suppl 2:128-34
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  • BACKGROUND: Serotonin (5-HT) and its receptors are present in central, the brain stem, and peripheral, the carotid body, tissues controlling the ventilatory responses to hypoxia.
  • In the functional part, the ventilatory responses to 8 and 12% hypoxia were compared before and 1 h after the compound administration using a whole body plethysmography.
  • Such molecules do not directly interfere with the carotid chemoreceptor-mediated hypoxic ventilatory response.
  • [MeSH-minor] Animals. Blood-Brain Barrier. Brain / metabolism. Caproates / pharmacology. Caprylates / pharmacology. Carotid Body / metabolism. Drug Stability. Male. Oleic Acids / pharmacology. Rats. Rats, Wistar

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  • (PMID = 21147640.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Caproates; 0 / Caprylates; 0 / Fatty Acids; 0 / Oleic Acids; 333DO1RDJY / Serotonin
  • [Other-IDs] NLM/ PMC4360274
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60. Ding Y, Li YL, Schultz HD: Downregulation of carbon monoxide as well as nitric oxide contributes to peripheral chemoreflex hypersensitivity in heart failure rabbits. J Appl Physiol (1985); 2008 Jul;105(1):14-23
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  • Downregulation of nitric oxide (NO) synthase (NOS) in the carotid body (CB) is involved in this effect.
  • Conversely, treatment with the NOS inhibitor N(omega)-nitro-L-arginine (30 mg/kg) + the heme oxygenase (HO) inhibitor Cr (III) mesoporphyrin IX chloride (0.5 mg/kg) augmented the renal sympathetic nerve response to hypoxia in sham rabbits to a greater extent than treatment with either inhibitor alone and was without effect in CHF rabbits.
  • In addition, using immunostaining and Western blot analyses, we found that expression of neuronal NOS, endothelial NOS, and HO-2 protein (expressed as the ratio of NOS or HO-2 expression to beta-tubulin protein expression) was lower in CBs from CHF (0.19 +/- 0.04, 0.17 +/- 0.06, and 0.15 +/- 0.02, respectively) than sham (0.63 +/- 0.04, 0.56 +/- 0.06, and 0.27 +/- 0.03, respectively) rabbits (P < 0.05).

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  • [Cites] J Appl Physiol (1985). 2007 Jan;102(1):37-43 [16902057.001]
  • [Cites] Science. 2004 Dec 17;306(5704):2093-7 [15528406.001]
  • [Cites] J Physiol. 1967 Feb;188(3):435-50 [6040584.001]
  • [Cites] Brain Res. 1975 Dec 12;100(1):13-23 [1182506.001]
  • [Cites] Science. 1992 Jul 24;257(5069):494-6 [1353273.001]
  • [Cites] Neuroscience. 1994 May;60(1):275-86 [7519759.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] Adv Exp Med Biol. 1994;360:57-69 [7872130.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1994-7 [7892214.001]
  • [Cites] FASEB J. 2005 Feb;19(2):284-6 [15556971.001]
  • [Cites] J Am Soc Nephrol. 2005 Apr;16(4):950-8 [15728782.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H92-8 [15734876.001]
  • [Cites] Circ Res. 2005 Aug 5;97(3):260-7 [15994433.001]
  • [Cites] Heart Fail Rev. 2000 Mar;5(1):45-56 [16228915.001]
  • [Cites] Cardiovasc Res. 2006 Jul 1;71(1):129-38 [16650840.001]
  • [Cites] Respir Physiol Neurobiol. 2007 Jul 1;157(1):171-85 [17374517.001]
  • [Cites] Circulation. 2000 Oct 10;102(15):1854-62 [11023943.001]
  • [Cites] Pflugers Arch. 2002 Mar;443(5-6):671-5 [11889563.001]
  • [Cites] J Physiol. 2002 Sep 15;543(Pt 3):933-45 [12231649.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L57-68 [12388352.001]
  • [Cites] J Physiol. 2004 Feb 15;555(Pt 1):219-29 [14673183.001]
  • [Cites] Bioessays. 2004 Mar;26(3):270-80 [14988928.001]
  • [Cites] Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H149-57 [16891408.001]
  • [Cites] Stroke. 1995 May;26(5):864-9 [7537926.001]
  • [Cites] Am Heart J. 1996 Oct;132(4):900-4 [8831388.001]
  • [Cites] Pharmacology. 1996 Mar;52(3):187-98 [8849488.001]
  • [Cites] Eur Heart J. 1997 Mar;18(3):480-6 [9076386.001]
  • [Cites] Circulation. 1997 Oct 21;96(8):2586-94 [9355898.001]
  • [Cites] Circ Res. 1998 Mar 9;82(4):496-502 [9506710.001]
  • [Cites] J Physiol. 1998 Aug 15;511 ( Pt 1):273-87 [9679181.001]
  • [Cites] Am J Cardiol. 1998 Aug 1;82(3):338-44 [9708664.001]
  • [Cites] J Appl Physiol (1985). 1999 Apr;86(4):1264-72 [10194212.001]
  • [Cites] J Appl Physiol (1985). 1999 Apr;86(4):1273-82 [10194213.001]
  • [Cites] Respir Physiol. 1999 Apr 1;115(2):161-8 [10385030.001]
  • [CommentIn] J Appl Physiol (1985). 2008 Jul;105(1):1-2 [18450975.001]
  • (PMID = 18356479.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / P01 HL062222; United States / NCRR NIH HHS / RR / P20 RR017675; United States / NHLBI NIH HHS / HL / P01-HL-62222; United States / NCRR NIH HHS / RR / P20-RR-17675
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Nitric Oxide Donors; 0 / Organometallic Compounds; 0 / tricarbonyldichlororuthenium (II) dimer; 31C4KY9ESH / Nitric Oxide; 7U1EE4V452 / Carbon Monoxide; EC 1.14.13.39 / Nitric Oxide Synthase; EC 1.14.99.3 / Heme Oxygenase (Decyclizing)
  • [Other-IDs] NLM/ PMC2494830
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61. Fitzgerald RS, Shirahata M, Chang I, Balbir A: L-arginine's effect on the hypoxia-induced release of acetylcholine from the in vitro cat carotid body. Respir Physiol Neurobiol; 2005 May 12;147(1):11-7
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  • [Title] L-arginine's effect on the hypoxia-induced release of acetylcholine from the in vitro cat carotid body.
  • NO is known to reduce the hypoxia-induced increase in carotid body neural activity (CBNA).
  • Acetylcholine (ACh), a known excitatory transmitter in the cat carotid body (CB), is released during hypoxia.
  • Two post-arginine procedures suggested strongly that the reduction in the ACh release was not due to a gradual exhaustion of carotid body ACh stores over the course of the experiment.
  • [MeSH-major] Acetylcholine / biosynthesis. Anoxia / physiopathology. Arginine / pharmacology. Carotid Body / drug effects

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  • (PMID = 15848119.001).
  • [ISSN] 1569-9048
  • [Journal-full-title] Respiratory physiology & neurobiology
  • [ISO-abbreviation] Respir Physiol Neurobiol
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL47044; United States / NHLBI NIH HHS / HL / HL50712
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 94ZLA3W45F / Arginine; N9YNS0M02X / Acetylcholine
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62. Davidovic L, Ilic N, Dimitrijevic M, Dukic V, Dzodic R: Surgical management of cervical paragangliomas. Am Surg; 2008 Dec;74(12):1171-6
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  • Carotid body tumors are rare, but represent the most common form of head and neck paraganglioma.
  • The present study reviews our experience in the diagnosis and treatment of these uncommon lesions.
  • A cervical approach was the method of choice in 16 cases; in one case with mediastinal extension of the tumor we used a combined cervical and transsternal approach.
  • Complete excision of the tumor was accomplished in all cases.
  • Subadventitial tumor excision was performed in eight cases whereas internal carotid artery reconstruction was obtained in eight cases (three saphenous interposition vein grafts, two polytetrafluoroethylene (PTFE) 6 mm grafts, and end-to-end anastomosis in three cases).
  • Resection of the left common carotid artery and reconstruction with a Dacron 8 mm graft was performed in the case with mediastinal tumor extension.
  • Duplex scan along with angiography is effective in making the diagnosis.
  • [MeSH-major] Carotid Body Tumor / surgery

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  • (PMID = 19097531.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Shen LG, Hu GH, Yu FJ: [Diagnosis and treatment of carotid body tumor]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Feb;43(2):157-60
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  • [Title] [Diagnosis and treatment of carotid body tumor].
  • [MeSH-major] Carotid Body Tumor / diagnosis. Carotid Body Tumor / therapy

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  • (PMID = 18510230.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
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64. Handa U, Bal A, Mohan H, Dass A: Parapharyngeal paraganglioma: diagnosis on fine-needle aspiration. Am J Otolaryngol; 2005 Sep-Oct;26(5):360-1
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  • [Title] Parapharyngeal paraganglioma: diagnosis on fine-needle aspiration.
  • Carotid body tumors constitute the third commonest group of parapharyngeal tumors.
  • Present case report is of carotid body paraganglioma diagnosed on FNA without any complications and thus providing definite preoperative diagnosis to the surgeon.
  • [MeSH-major] Biopsy, Fine-Needle. Carotid Body / pathology. Carotid Body Tumor / diagnosis

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  • (PMID = 16137540.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Cardot V, Chardon K, Tourneux P, Micallef S, Stéphan E, Léké A, Bach V, Libert JP, Telliez F: Ventilatory response to a hyperoxic test is related to the frequency of short apneic episodes in late preterm neonates. Pediatr Res; 2007 Nov;62(5):591-6
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  • Apnea could result from a decrease in carotid body effectiveness.
  • However, increased carotid body activity could also initiate apnea through hypocapnia following hyperventilation when the receptors are stimulated.
  • The aim of this study was to analyze the relationship between carotid body effectiveness and short apneic episodes in older preterm neonates.
  • Carotid body effectiveness was assessed at thermoneutrality in 36 premature neonates (2.07 +/- 0.26 kg) by performing a 30-s hyperoxic test during sleep, the oxygen inhalation involving a ventilation decrease.
  • Increased carotid body response is correlated with greater apneic episodes frequency, even in the absence of concomitant oxygen desaturation.
  • [MeSH-major] Carotid Body / physiopathology. Hyperoxia / physiopathology. Infant, Premature. Pulmonary Ventilation. Sleep Apnea Syndromes / physiopathology

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  • (PMID = 17805205.001).
  • [ISSN] 0031-3998
  • [Journal-full-title] Pediatric research
  • [ISO-abbreviation] Pediatr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] S88TT14065 / Oxygen
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67. Yamaguchi S, Balbir A, Okumura M, Schofield B, Coram J, Tankersley CG, Fitzgerald RS, O'Donnell CP, Shirahata M: Genetic influence on carotid body structure in DBA/2J and A/J strains of mice. Adv Exp Med Biol; 2006;580:105-9; discussion 351-9
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  • [Title] Genetic influence on carotid body structure in DBA/2J and A/J strains of mice.
  • [MeSH-major] Carotid Body / growth & development

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  • (PMID = 16683705.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL 61596; United States / NHLBI NIH HHS / HL / HL 72293
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.14.16.2 / Tyrosine 3-Monooxygenase
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68. Hurtado-Lopez LM, Fink-Josephi G, Ramos-Méndez L, Dena-Espinoza E: Nonresectable carotid body tumor: hybrid surgical procedure to achieve complete and safe resection. Head Neck; 2008 Dec;30(12):1646-9
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  • [Title] Nonresectable carotid body tumor: hybrid surgical procedure to achieve complete and safe resection.
  • BACKGROUND: Carotid body tumors of Shamblin class III without free internal carotid, between the tumor and skull base, are considered nonresectable.
  • The objective of this work is to describe a surgical technique that combines traditional and endovascular strategies to achieve a safe surgical resection of the carotid body tumor of this class.
  • METHODS AND RESULTS: A female patient with a nonresectable carotid body tumor underwent placement of an endoprosthesis going from the common carotid artery to the internal carotid beyond the skull base (to secure cerebral circulation) excluding the external carotid artery.
  • Forty-five days later, the tumor was resected without vascular or cranial nerves injury, and bleeding amounted to 50 cm(3).
  • At 6 months, the patient is tumor free and asymptomatic.
  • The endoprosthesis maintained cerebral circulation, which otherwise would have been impossible; besides, the vascular supply from the external carotid artery was excluded leading to a decrease in tumor size and a recovery of the sub-adventitial dissection plane, allowing for a successful and safe tumor resection.
  • [MeSH-major] Blood Vessel Prosthesis. Carotid Body Tumor / surgery. Vascular Surgical Procedures / methods

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc.
  • (PMID = 18302274.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. De Castro F: The discovery of sensory nature of the carotid bodies--invited article. Adv Exp Med Biol; 2009;648:1-18
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  • [Title] The discovery of sensory nature of the carotid bodies--invited article.
  • Although the carotid body (or glomus caroticum) was a structure familiar to anatomists in the XVIIIth century, it was not until the beginning of the XXth century that its role was revealed.
  • It was then that the German physiologist Heinrich Hering described the respiratory reflex and he began to study the anatomical basis of this reflex focusing on the carotid region, and the carotid sinus in particular.
  • However, at the Laboratorio de Investigaciones Biológicas (Madrid, Spain), one of the youngest and more brilliant disciples of Santiago Ramón y Cajal, Fernando De Castro, took advantage of certain technical advances to study the fine structure of the carotid body (De Castro, 1925).
  • In successive papers (1926, 1928, 1929), De Castro unravelled most of the histological secrets of this small structure and described the exact localisation of the "chemoreceptors" within the glomus.
  • Heymans was deeply interested in the work of De Castro, and he extended two invitations to the Spanish neurologist to visit (1929 and 1932) so that they could share their experiences.
  • From 1932-1933, Corneille Heymans focused his attention on the carotid body and his physiological demonstration of De Castro's hypothesis regarding chemoreceptors led to him obtaining the Nobel Prize in Physiology or Medicine in 1938, while Spain was immersed in its catastrophic Civil War.
  • [MeSH-major] Carotid Body. Physiology / history

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  • (PMID = 19536460.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Personal-name-as-subject] De Castro F; Heymans C
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70. Szymańska A, Gołabek W, Szymański M, Morshed K, Trojanowska A: [Diagnostic evaluation of temporal paragangliomas]. Otolaryngol Pol; 2007;61(6):931-6
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  • Head and neck paragangliomas are divided into two groups: neck tumours (carotid body tumor and vagal paraganglioma) and temporal paragangliomas (jugular bulb tumor and tympanic paraganglioma).
  • Radiological evaluation of these lesions is essential for confirming the diagnosis and surgery planning.
  • Carotid angiography is a second step diagnostic method, performed in patients with jugular bulb paraganglioma.
  • It has a diagnostic value and allows palliative or preoperative embolization of the tumor.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Paraganglioma / diagnosis

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  • (PMID = 18546938.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 15
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71. Giannoni MF, Irace L, Vicenzini E, Massa R, Gossetti B, Benedetti-Valentini F: Carotid body tumors: advantages of contrast ultrasound investigation. J Neuroimaging; 2009 Oct;19(4):388-90
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  • [Title] Carotid body tumors: advantages of contrast ultrasound investigation.
  • Carotid body tumors are rare neoplasms that have to be considered in the evaluation of all lateral neck mass.
  • Computed tomography (CT) and magnetic resonance imaging (MRA) angiographies are the preferred pre-operative diagnostic imaging investigations, as well as the 111 In-pentetreotide scintigraphic scan, whereas the standard ultrasound investigations have poor sensitivity in characterizing of the blood flows of the parenchimal structure of the carotid body tumors.
  • We describe a case of a patient with a carotid body tumor assessed with contrast ultrasonography that clearly improved the quality of the standard color Duplex.
  • [MeSH-major] Carotid Body Tumor / ultrasonography. Contrast Media
  • [MeSH-minor] Aged. Angiography. Carotid Arteries / radiography. Carotid Arteries / radionuclide imaging. Carotid Arteries / ultrasonography. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Indium Radioisotopes. Tomography, X-Ray Computed. Treatment Outcome. Ultrasonography, Doppler, Duplex

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  • (PMID = 19021824.001).
  • [ISSN] 1552-6569
  • [Journal-full-title] Journal of neuroimaging : official journal of the American Society of Neuroimaging
  • [ISO-abbreviation] J Neuroimaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Indium Radioisotopes
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72. Pawar A, Peng YJ, Jacono FJ, Prabhakar NR: Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia. J Appl Physiol (1985); 2008 May;104(5):1287-94
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  • [Title] Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia.
  • Previous studies suggest that carotid body responses to long-term changes in environmental oxygen differ between neonates and adults.
  • In the present study we tested the hypothesis that the effects of chronic intermittent hypoxia (CIH) on the carotid body differ between neonates and adult rats.
  • Sensory activity was recorded from ex vivo carotid bodies.
  • Seventy-two episodes of CIH were sufficient to evoke hypoxic sensitization in neonates, whereas as many as 720 CIH episodes were required in adults, suggesting that neonatal carotid bodies are more sensitive to CIH than adult carotid bodies.
  • Acute intermittent hypoxia (IH) evoked sensory long-term facilitation of the carotid body activity (sensory LTF, i.e., increased baseline neural activity following acute IH) in CIH-exposed adults but not in neonates.
  • The effects of CIH were associated with hyperplasia of glomus cells in neonatal but not in adult carotid bodies.

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  • [Cites] J Appl Physiol (1985). 2004 Nov;97(5):2020-5 [15258129.001]
  • [Cites] Am J Respir Crit Care Med. 2001 Jan;163(1):19-25 [11208620.001]
  • [Cites] Biochem Pharmacol. 1976 Nov 1;25(21):2387-90 [999726.001]
  • [Cites] Brain Res. 1983 Oct 16;276(2):348-50 [6354361.001]
  • [Cites] J Physiol. 1984 Jun;351:25-37 [6747866.001]
  • [Cites] Am J Obstet Gynecol. 1987 Sep;157(3):743-8 [3631176.001]
  • [Cites] Biol Neonate. 1994;65(3-4):211-9 [8038285.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):821-6 [11792862.001]
  • [Cites] J Appl Physiol (1985). 2003 Jan;94(1):375-89 [12486025.001]
  • [Cites] Acta Physiol Scand. 2003 Mar;177(3):377-84 [12609009.001]
  • [Cites] J Appl Physiol (1985). 2003 Sep;95(3):946-52 [12909596.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10073-8 [12907705.001]
  • [Cites] J Appl Physiol (1985). 2004 Mar;96(3):1236-42; discussion 1196 [14660510.001]
  • [Cites] J Physiol. 2006 Dec 1;577(Pt 2):705-16 [16973705.001]
  • [Cites] Exp Physiol. 2007 Jan;92(1):39-44 [17124274.001]
  • [Cites] J Physiol. 2004 Oct 15;560(Pt 2):577-86 [15319419.001]
  • [Cites] Biol Signals. 1995 Sep-Oct;4(5):292-7 [8704830.001]
  • [Cites] J Physiol. 1999 Jan 15;514 ( Pt 2):493-503 [9852330.001]
  • [Cites] Am J Physiol. 1999 Sep;277(3 Pt 1):L645-52 [10484473.001]
  • [Cites] J Appl Physiol (1985). 2005 Apr;98(4):1469-77 [15591286.001]
  • [Cites] J Neurosci. 2005 Apr 20;25(16):4091-8 [15843611.001]
  • [Cites] Pediatr Res. 2005 Jul;58(1):53-7 [15879294.001]
  • [Cites] J Neurochem. 2006 Feb;96(3):694-705 [16390493.001]
  • [Cites] Prog Biophys Mol Biol. 2006 Jul;91(3):249-86 [16137743.001]
  • [Cites] J Physiol. 2006 Oct 1;576(Pt 1):289-95 [16887872.001]
  • [Cites] Neurosci Lett. 2000 Jan 7;278(1-2):9-12 [10643788.001]
  • [Cites] JAMA. 2000 Apr 12;283(14):1829-36 [10770144.001]
  • [Cites] J Appl Physiol (1985). 2000 Jun;88(6):2296-301 [10846048.001]
  • [Cites] Brain Res. 2000 Jul 28;872(1-2):199-203 [10924693.001]
  • [Cites] J Neurosci. 2001 Jan 15;21(2):581-9 [11160437.001]
  • [CommentIn] J Appl Physiol (1985). 2008 May;104(5):1260-1 [18323459.001]
  • (PMID = 18187605.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / P01 HL025830; United States / NHLBI NIH HHS / HL / R01 HL076537; United States / NHLBI NIH HHS / HL / HL 076537; United States / NHLBI NIH HHS / HL / HL 25830
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS524553; NLM/ PMC3893879
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73. Zapata P, Larraín C: How the carotid body works: different strategies and preparations to solve different problems. Biol Res; 2005;38(4):315-28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] How the carotid body works: different strategies and preparations to solve different problems.
  • An analysis is performed oi the bases, advantages and limits of the following preparations: studies of ventilatory reflexes originated from carotid bodies (CBs) in the entire animal; recordings of CB chemosensory discharges in situ; CB preparations perfused in situ; CB explants in oculo; CB explants in ovo; CB preparations incubated in vitro; CB preparations superfused in vitro; CB preparations perfused and superfused in vitro: CB tissue slices in vitro; cells acutely dissociated from CBs; CB cells in tissue culture; petrosal ganglia superfused in vitro; petrosal ganglion cells in tissue culture; and co-cultures of CB and sensory ganglion cells.
  • [MeSH-major] Carotid Body / physiology. Chemoreceptor Cells / physiology. Culture Techniques / methods. Models, Biological

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  • (PMID = 16579512.001).
  • [ISSN] 0716-9760
  • [Journal-full-title] Biological research
  • [ISO-abbreviation] Biol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Chile
  • [Number-of-references] 128
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74. Prabhakar NR, Peng YJ, Kumar GK, Nanduri J, Di Giulio C, Lahiri S: Long-term regulation of carotid body function: acclimatization and adaptation--invited article. Adv Exp Med Biol; 2009;648:307-17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term regulation of carotid body function: acclimatization and adaptation--invited article.
  • Physiological responses to hypoxia either continuous (CH) or intermittent (IH) depend on the O(2)-sensing ability of the peripheral arterial chemoreceptors, especially the carotid bodies, and the ensuing reflexes play important roles in maintaining homeostasis.
  • The purpose of this article is to summarize the effects of CH and IH on carotid body function and the underlying mechanisms.
  • CH increases baseline carotid body activity and sensitizes the response to acute hypoxia.
  • These effects are associated with hyperplasia of glomus cells and neovascularization.
  • Enhanced hypoxic sensitivity is due to alterations in ion current densities as well as changes in neurotransmitter dynamics and recruitment of additional neuromodulators (endothelin-1, ET-1) in glomus cells.
  • Hypoxia-inducible factor-1 (HIF-1), a transcriptional activator might underlie the remodeling of carotid body structure and function by CH.
  • Two major effects of chronic IH on the adult carotid body are sensitization of the hypoxic sensory response and long-lasting increase in baseline activity i.e., sensory long-term facilitation (LTF) which involve reactive oxygen species (ROS) and HIF-1.
  • Chronic IH-induced sensitization of the carotid body response to hypoxia increases the likelihood of unstable breathing perpetuating in more number of apneas, whereas sensory LTF may contribute to increased sympathetic tone and systemic hypertension associated with recurrent apneas.

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  • [Cites] Acta Physiol Scand. 2003 Mar;177(3):377-84 [12609009.001]
  • [Cites] J Appl Physiol (1985). 2003 Jan;94(1):375-89 [12486025.001]
  • [Cites] Adv Exp Med Biol. 2003;536:583-91 [14635716.001]
  • [Cites] J Appl Physiol (1985). 2004 Mar;96(3):1236-42; discussion 1196 [14660510.001]
  • [Cites] J Appl Physiol (1985). 2004 Nov;97(5):2020-5 [15258129.001]
  • [Cites] J Physiol. 2004 Oct 15;560(Pt 2):577-86 [15319419.001]
  • [Cites] Neuroscience. 1981;6(1):81-6 [7219707.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1984 Nov;57(5):1430-8 [6520037.001]
  • [Cites] Respir Physiol. 1987 Aug;69(2):245-55 [3629011.001]
  • [Cites] J Appl Physiol (1985). 1987 Aug;63(2):685-91 [3654428.001]
  • [Cites] Pneumologie. 1991 May;45 Suppl 1:309-11 [1866415.001]
  • [Cites] J Neurochem. 1992 Apr;58(4):1538-46 [1347783.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9469-73 [1329096.001]
  • [Cites] Sleep. 1993 Dec;16(8 Suppl):S30-3; discussion S33-4 [8178019.001]
  • [Cites] Biol Neonate. 1994;65(3-4):211-9 [8038285.001]
  • [Cites] Physiol Rev. 1994 Oct;74(4):829-98 [7938227.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):295-9 [7529413.001]
  • [Cites] Physiol Rev. 1996 Jul;76(3):839-85 [8757790.001]
  • [Cites] J Physiol. 1995 Dec 15;489 ( Pt 3):689-99 [8788934.001]
  • [Cites] J Neurophysiol. 1996 Sep;76(3):1880-6 [8890300.001]
  • [Cites] Adv Exp Med Biol. 1996;410:305-11 [9030316.001]
  • [Cites] J Neurophysiol. 1997 Nov;78(5):2467-74 [9356397.001]
  • [Cites] Genes Dev. 1998 Jan 15;12(2):149-62 [9436976.001]
  • [Cites] J Hypertens. 1997 Dec;15(12 Pt 2):1593-603 [9488210.001]
  • [Cites] Comp Biochem Physiol A Mol Integr Physiol. 1998 Jun;120(2):243-7 [9773503.001]
  • [Cites] Brain Res. 1998 Dec 14;814(1-2):213-7 [9838124.001]
  • [Cites] J Clin Invest. 1999 Mar;103(5):691-6 [10074486.001]
  • [Cites] High Alt Med Biol. 2005 Summer;6(2):97-111 [16060845.001]
  • [Cites] Exp Physiol. 2006 Jan;91(1):17-23 [16239252.001]
  • [Cites] Brain Res. 2006 May 1;1086(1):152-9 [16595126.001]
  • [Cites] J Physiol. 2006 Oct 1;576(Pt 1):289-95 [16887872.001]
  • [Cites] J Physiol. 2006 Dec 1;577(Pt 2):705-16 [16973705.001]
  • [Cites] Histol Histopathol. 2008 Mar;23(3):271-80 [18072084.001]
  • [Cites] J Appl Physiol (1985). 2008 May;104(5):1287-94 [18187605.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R735-42 [19109370.001]
  • [Cites] Laryngoscope. 2000 Jan;110(1):161-7 [10646734.001]
  • [Cites] Brain Res Mol Brain Res. 2000 Feb 22;75(2):264-70 [10686347.001]
  • [Cites] J Appl Physiol (1985). 2000 Apr;88(4):1474-80 [10749844.001]
  • [Cites] J Appl Physiol (1985). 2000 Jun;88(6):2287-95 [10846047.001]
  • [Cites] Respir Physiol. 2000 Jun;121(1):13-23 [10854619.001]
  • [Cites] Respir Physiol. 2000 Jul;121(2-3):237-46 [10963778.001]
  • [Cites] Annu Rev Physiol. 2001;63:259-87 [11181957.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):821-6 [11792862.001]
  • [Cites] Pflugers Arch. 2002 Feb;443(4):565-73 [11907823.001]
  • [Cites] Pflugers Arch. 2002 May;444(1-2):178-85 [11976930.001]
  • [Cites] Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1314-23 [12003788.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10073-8 [12907705.001]
  • (PMID = 19536494.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL076537; United States / NHLBI NIH HHS / HL / HL-90554; United States / NHLBI NIH HHS / HL / R01 HL086493; United States / NHLBI NIH HHS / HL / HL-76537; United States / NHLBI NIH HHS / HL / P01 HL090554
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Number-of-references] 49
  • [Other-IDs] NLM/ NIHMS523769; NLM/ PMC3893881
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75. Tano GD, Petrarca C, Bosco G, Pasquale B, Yang Z, Morelli L, Barbacane R, Loffredo B: Identification and Measurement of Carbonic Anhydrase-II Molecule Numbers in the Rat Carotid Body. Open Respir Med J; 2009;3:67-72
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  • [Title] Identification and Measurement of Carbonic Anhydrase-II Molecule Numbers in the Rat Carotid Body.
  • Carbonic anhydrase (CA) in the carotid body (CB) plays an important role in the maintenance of blood PO2 and PCO2/pH homeostasis by regulating ventilation.

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  • [Cites] J Virol. 1994 Aug;68(8):5133-41 [8035513.001]
  • [Cites] J Appl Physiol (1985). 1991 Mar;70(3):1393-400 [1903380.001]
  • [Cites] Mol Immunol. 1985 Mar;22(3):215-21 [2582242.001]
  • [Cites] Bioessays. 1989 Jun;10(6):186-92 [2500929.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1984 Oct;57(4):931-57 [6150019.001]
  • [Cites] J Appl Physiol Respir Environ Exerc Physiol. 1984 Nov;57(5):1430-8 [6520037.001]
  • [Cites] Neurosci Lett. 1994 Jan 31;166(2):126-30 [8177488.001]
  • [Cites] Biochim Biophys Acta. 1977 Apr 12;481(2):712-21 [403951.001]
  • [Cites] Anal Biochem. 1975 Mar;64(1):297-303 [806235.001]
  • [Cites] Nature. 1970 Aug 15;227(5259):680-5 [5432063.001]
  • [Cites] J Anat. 2003 Jun;202(6):573-7 [12846478.001]
  • [Cites] JOP. 2001 Jul;2(4 Suppl):159-64 [11875253.001]
  • [Cites] Enzymol Biol Clin (Basel). 1964;10:199-216 [14227360.001]
  • [Cites] Ann N Y Acad Sci. 1984;429:398-400 [6204572.001]
  • (PMID = 19572025.001).
  • [ISSN] 1874-3064
  • [Journal-full-title] The open respiratory medicine journal
  • [ISO-abbreviation] Open Respir Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC2703206
  • [Keywords] NOTNLM ; Carbonic anhydrase / Carotid body / Phosphor imaging / SDS-PAGE / Western blot.
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76. Igarashi A, Zadzilka N, Shirahata M: Benzodiazepines and GABA-GABAA receptor system in the cat carotid body. Adv Exp Med Biol; 2009;648:169-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benzodiazepines and GABA-GABAA receptor system in the cat carotid body.
  • (1) to identify GABA(A) receptor subunits in the carotid body (CB) and petrosal ganglion (PG);.
  • Immunoreactivity for GABA and for GABA(A) receptor beta3 and gamma2 subunits was detected in chemosensory glomus cells (GCs) in the CB and neurons in the PG.
  • [MeSH-major] Benzodiazepines / pharmacology. Carotid Body / drug effects. Carotid Body / metabolism. Receptors, GABA-A / metabolism. gamma-Aminobutyric Acid / metabolism
  • [MeSH-minor] Animals. Anoxia / metabolism. Carotid Sinus / drug effects. Carotid Sinus / innervation. Carotid Sinus / physiology. Cats. Immunohistochemistry. In Vitro Techniques. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 19536478.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL72293
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, GABA-A; 12794-10-4 / Benzodiazepines; 56-12-2 / gamma-Aminobutyric Acid
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77. Wyatt CN, Kumar P, Aley P, Peers C, Hardie DG, Evans AM: Does AMP-activated protein kinase couple hypoxic inhibition of oxidative phosphorylation to carotid body excitation? Adv Exp Med Biol; 2006;580:191-6; discussion 351-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does AMP-activated protein kinase couple hypoxic inhibition of oxidative phosphorylation to carotid body excitation?
  • [MeSH-major] Carotid Body / metabolism. Cell Hypoxia / physiology. Multienzyme Complexes / metabolism. Protein-Serine-Threonine Kinases / metabolism

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  • (PMID = 16683718.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 070772
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Multienzyme Complexes; 0 / Ribonucleotides; 360-97-4 / Aminoimidazole Carboxamide; EC 2.7.11.1 / AMP-Activated Protein Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; F0X88YW0YK / AICA ribonucleotide
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78. Iturriaga R, Alcayaga J, Gonzalez C: Neurotransmitters in carotid body function: the case of dopamine--invited article. Adv Exp Med Biol; 2009;648:137-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurotransmitters in carotid body function: the case of dopamine--invited article.
  • The carotid body (CB) is the main peripheral chemoreceptor.
  • The present model of CB chemoreception states that glomus (type I) cells are the primary receptors, which are synaptically connected to the nerve terminals of the petrosal ganglion neurons.
  • In response to hypoxia, hypercapnia and acidosis, glomus cells release one (or more) transmitter(s) which, acting on the nerve terminals of chemosensory neurons, increases the afferent discharge.
  • Among several molecules present in glomus cells, dopamine, acetylcholine and 5'-adenosine-triphosphate have been proposed to be the excitatory transmitters in the CB.
  • Beside these putative excitatory transmitters, other molecules modulate the chemosensory process through direct actions on glomus cells and/or by producing tonic effects on CB blood vessels.
  • [MeSH-major] Carotid Body / cytology. Carotid Body / metabolism. Dopamine / metabolism. Neurotransmitter Agents / metabolism

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  • (PMID = 19536475.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neurotransmitter Agents; VTD58H1Z2X / Dopamine
  • [Number-of-references] 33
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79. Hu Y, Hua Q, Jiang Y: [Diagnosis and treatment of carotid body tumors]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Nov;24(21):961-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and treatment of carotid body tumors].
  • OBJECTIVE: To study the diagnosis and therapy of carotid body tumors.
  • METHOD: A total of 44 patients with carotid body tumors were received and cured in people's hospital of Wuhan University from 1990 to 2010.
  • Two of them were bilateral carotid body tumor patients.
  • Among these patients, 39 of them were undertaken only tumor resecting, 6 were performed resecting of both tumors and external carotid artery and 1 were subjected to tumor resecting including internal carotid artery.
  • CONCLUSION: The most effective way to cure carotid body tumor is surgical operation.
  • [MeSH-major] Carotid Body Tumor / diagnosis. Carotid Body Tumor / surgery

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  • (PMID = 21261012.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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80. Powell FL, Kim BC, Johnson SR, Fu Z: Oxygen sensing in the brain--invited article. Adv Exp Med Biol; 2009;648:369-76
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  • Carotid body arterial chemoreceptors are essential for a normal hypoxic ventilatory response (HVR) and ventilatory acclimatization to hypoxia (VAH).
  • The cellular and molecular mechanisms of acute O(2)-sensing in the brain remain to be determined but they appear to involve O(2)-sensitive ion channels and heme oxygenase-2, which acts by a different mechanism than has been described for the carotid body.

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  • (PMID = 19536501.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL081823; United States / NHLBI NIH HHS / HL / R01-HL081823
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] S88TT14065 / Oxygen
  • [Number-of-references] 26
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81. Athanasiou A, Liappis CD, Rapidis AD, Fassolis A, Stavrianos SD, Kokkalis G: Carotid body tumor: review of the literature and report of a case with a rare sensorineural symptomatology. J Oral Maxillofac Surg; 2007 Jul;65(7):1388-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carotid body tumor: review of the literature and report of a case with a rare sensorineural symptomatology.
  • [MeSH-major] Carotid Body Tumor / complications. Head and Neck Neoplasms / complications
  • [MeSH-minor] Carotid Arteries / pathology. Dysgeusia / etiology. Earache / etiology. Humans. Hypertension / etiology. Magnetic Resonance Angiography. Male. Middle Aged. Subtraction Technique. Vertebral Artery / pathology

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  • (PMID = 17577510.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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82. Jayaram G, Kaliaperumal S, Kumar G: Bilateral carotid body tumor diagnosed on cytology. Acta Cytol; 2005 Nov-Dec;49(6):690-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral carotid body tumor diagnosed on cytology.
  • [MeSH-major] Carotid Body Tumor / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle / methods. Diagnosis, Differential. Humans. Male. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 16450914.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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83. Nimbkar NV, Lateef F: Treatment of essential hypertension and non-insulin dependent diabetes mellitus with vitamin C. Med Hypotheses; 2007;68(5):1126-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inappropriate response of the carotid body region to encroachment of its perfusion results in essential hypertension (EH) and/or non-insulin dependent diabetes mellitus (NIDDM).
  • The carotid body perceives the encroachment on the lumen as a reduction in the availability of oxygen and glucose for the brain.
  • Therefore, the reduction or reversal of the atherosclerosis process will help improve perfusion to the carotid bodies, which will in turn reduce or reverse the pathophysiological compensatory adjustments described above.


84. Saddoud N, Turki I, Chammakhi R, Ben Reguiga M, Nouira K, Menif E: [Malignant paraganglioma with vertebral and skull metastasis]. J Radiol; 2006 Dec;87(12 Pt 1):1887-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Paragangliome malin avec métastases vertébrales et de la voûte crânienne.
  • A paraganglioma is a rare tumor composed of chromaffin cells.
  • We report a case of a 30-year-old man who had undergone a carotid body tumor resection 10 years before and who presented to us with recurrence of the tumor associated with lymph node, vertebra and skull metastasis.
  • The diagnosis of malignant paraganglioma was based on loco-regional and distant metastasis.
  • [MeSH-major] Carotid Body Tumor / secondary. Cervical Vertebrae. Skull Neoplasms / secondary. Spinal Neoplasms / secondary

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  • (PMID = 17213774.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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85. Pardal R, Ortega-Sáenz P, Durán R, Platero-Luengo A, López-Barneo J: The carotid body, a neurogenic niche in the adult peripheral nervous system. Arch Ital Biol; 2010 Jun;148(2):95-105
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The carotid body, a neurogenic niche in the adult peripheral nervous system.
  • We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the peripheral nervous system.
  • [MeSH-major] Adult Stem Cells / physiology. Carotid Body / cytology. Neurogenesis / physiology. Peripheral Nervous System / cytology

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  • (PMID = 20830972.001).
  • [ISSN] 0003-9829
  • [Journal-full-title] Archives italiennes de biologie
  • [ISO-abbreviation] Arch Ital Biol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Italy
  • [Number-of-references] 51
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86. Mithani SK, Marohn MR, Freischlag JA, Dackiw AP, Zeiger MA: Laparoscopic resection of a paraganglioma of the organ of Zuckerkandl in a patient with a carotid body tumor. Am Surg; 2006 Jan;72(1):55-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic resection of a paraganglioma of the organ of Zuckerkandl in a patient with a carotid body tumor.
  • Paraganglioma of the organ of Zuckerkandl with synchronous carotid body paraganglioma is described herein.
  • In this manuscript, we describe one of the first reported laparoscopic resections of this tumor and review the literature on multiple paragangliomas and their associated genetic syndromes.
  • [MeSH-minor] Adult. Carotid Body Tumor / pathology. Carotid Body Tumor / radiography. Diagnosis, Differential. Female. Humans. Magnetic Resonance Angiography. Tomography, X-Ray Computed

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  • (PMID = 16494184.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Pardal R, Ortega-Sáenz P, Durán R, López-Barneo J: Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body. Cell; 2007 Oct 19;131(2):364-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body.
  • We have discovered stem cells in the adult carotid body (CB), an oxygen-sensing organ of the sympathoadrenal lineage that grows in chronic hypoxemia.
  • Production of new neuron-like CB glomus cells depends on a population of stem cells, which form multipotent and self-renewing colonies in vitro.
  • Remarkably, stem cell-derived glomus cells have the same complex chemosensory properties as mature in situ glomus cells.
  • [MeSH-major] Carotid Body / cytology. Neuroglia / cytology. Neurons / cytology. Stem Cells / cytology


88. Montero SA, Cadenas JL, Lemus M, Roces de Alvarez-Buylla E, Alvarez-Buylla R: Nitric oxide in brain glucose retention after carotid body receptors stimulation with cyanide in rats. Adv Exp Med Biol; 2006;580:293-300; discussion 351-9
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  • [Title] Nitric oxide in brain glucose retention after carotid body receptors stimulation with cyanide in rats.
  • [MeSH-major] Brain / metabolism. Carotid Body / metabolism. Glucose / metabolism. Nitric Oxide / metabolism

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  • (PMID = 16683734.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 31C4KY9ESH / Nitric Oxide; G59M7S0WS3 / Nitroglycerin; IY9XDZ35W2 / Glucose; O5DDB9Z95G / Sodium Cyanide; V55S2QJN2X / NG-Nitroarginine Methyl Ester
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89. Tall A, Diarra O, Dieng MM, Diallo BK, Ndiaye M, Niang E, Essalki I, Diouf R, Ndiaye IC, Diop EM: [Head and neck paragangliomas in Senegal. About 8 cases]. Ann Otolaryngol Chir Cervicofac; 2005 Dec;122(6):287-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Paragangliomes de la tête et du cou au Sénégal.
  • The study concerned 8 patients with a highly vascular tumor located in the neck and temporal bone.
  • Histological examination of the tumor was realized in all cases.
  • RESULTS: The tumor was located in the neck in 5 cases (62,5%) with a carotid body tumor in three patients (37,5%) and vagal location in two (25%).
  • In the third patient with a tympano-jugular tumor, with important involvement of the temporal bone, only the neck extension was operated.
  • The histological diagnosis of paraganglioma was confirmed in all patients.
  • Radiation therapy was delivered in two patients (25%), to complete surgery in the event of extensive temporal bone tumor and exclusive in one case of an inoperable vagal tumor.
  • [MeSH-minor] Adolescent. Adult. Carotid Body Tumor / pathology. Carotid Body Tumor / radiography. Carotid Body Tumor / surgery. Female. Humans. Jugular Veins / pathology. Jugular Veins / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Senegal. Temporal Bone / pathology. Temporal Bone / radiography. Temporal Bone / surgery. Tomography, X-Ray Computed

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  • (PMID = 16505779.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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90. Patlola R, Ingraldi A, Walker C, Allie D, Khan IA: Carotid body tumor. Int J Cardiol; 2010 Aug 6;143(1):e7-e10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carotid body tumor.
  • Carotid body tumors are the most common paragangliomas of head and neck.
  • Most of these tumors are benign with a small malignant potential.
  • In younger, healthy patients with no comorbidities, the best therapeutic strategy is a complete excision of the tumor.
  • However, in less than ideal patient population modalities such as radiation and tumor embolization can be considered.
  • [MeSH-major] Carotid Artery, External / radiography. Carotid Artery, Internal / radiography. Carotid Body Tumor / radiography. Carotid Body Tumor / surgery. Tomography, Spiral Computed

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  • [Copyright] Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19155078.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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91. Li Q, Sun B, Wang X, Jin Z, Zhou Y, Dong L, Jiang LH, Rong W: A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels. Antioxid Redox Signal; 2010 May 15;12(10):1179-89
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  • Here we examined the role of H(2)S in the oxygen-sensing function of the carotid body chemoreceptors, where the large conductance Ca(2+)-activated potassium channel (BK(Ca)) plays a key role.
  • In the isolated mouse carotid body/sinus nerve preparations, the H(2)S donor, NaHS, excited the chemoreceptor afferent nerves in a concentration-dependent manner that was reversed by carbon monoxide donor.
  • The NaHS-evoked excitation was abolished by removing extracellular Ca(2+), or using Cd(2+), pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid and hexomethonium, suggesting that H(2)S evokes release of ATP/ACh from type I glomus cells of the carotid body.
  • The chemoreceptor afferent activation by hypoxia was decreased remarkably using CBS inhibitors, amino oxyacetic acid (AOAA) and hydroxylamine, but not CSE inhibitors, propargylglycine and beta-cyano-L-alanine, despite expression of both enzymes in type I glomus cells.
  • These data suggest that H(2)S plays a crucial role in mediating the response of carotid body chemoreceptors to hypoxia via modulating the BK(Ca) channels.
  • [MeSH-major] Carotid Body / metabolism. Hydrogen Sulfide / metabolism. Large-Conductance Calcium-Activated Potassium Channels / metabolism. Oxygen / metabolism
  • [MeSH-minor] Afferent Pathways / physiology. Air Pollutants / metabolism. Animals. Anoxia / metabolism. Carbon Monoxide / metabolism. Chemoreceptor Cells / cytology. Chemoreceptor Cells / metabolism. Mice. Patch-Clamp Techniques. Plethysmography, Whole Body

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  • (PMID = 19803741.001).
  • [ISSN] 1557-7716
  • [Journal-full-title] Antioxidants & redox signaling
  • [ISO-abbreviation] Antioxid. Redox Signal.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Air Pollutants; 0 / Large-Conductance Calcium-Activated Potassium Channels; 7U1EE4V452 / Carbon Monoxide; S88TT14065 / Oxygen; YY9FVM7NSN / Hydrogen Sulfide
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92. Spyer KM: To breathe or not to breathe? That is the question. Exp Physiol; 2009 Jan;94(1):1-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • New insights into the transduction mechanisms of chemoreception in the carotid body and chemosensitive areas of the ventral medullary surface, specifically in monitoring CO(2) levels, are reviewed.
  • [MeSH-minor] Animals. Carbon Dioxide / metabolism. Cardiovascular Physiological Phenomena. Carotid Body / physiology. Homeostasis / physiology. Humans. Oxygen / metabolism. Synaptic Transmission / physiology

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  • (PMID = 19042981.001).
  • [ISSN] 1469-445X
  • [Journal-full-title] Experimental physiology
  • [ISO-abbreviation] Exp. Physiol.
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / ; United Kingdom / Medical Research Council / / ; United Kingdom / Wellcome Trust / /
  • [Publication-type] Lectures; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide; S88TT14065 / Oxygen
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93. Yi L, Morgan JT, Ragsdale SW: Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and CO. J Biol Chem; 2010 Jun 25;285(26):20117-27
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  • The human BK channel, which is a large-conductance Ca(2+) and voltage-activated K(+) channel, is involved in the hypoxic response in the carotid body.

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  • [Cites] Annu Rev Physiol. 2001;63:259-87 [11181957.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4039-43 [18316727.001]
  • [Cites] J Gen Physiol. 2001 Mar;117(3):253-74 [11222629.001]
  • [Cites] Neuron. 2001 Mar;29(3):593-601 [11301020.001]
  • [Cites] EMBO J. 2001 Jun 1;20(11):2835-43 [11387216.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):10996-1002 [11572959.001]
  • [Cites] Methods Enzymol. 2002;348:93-112 [11885298.001]
  • [Cites] J Physiol. 2002 May 1;540(Pt 3):771-80 [11986367.001]
  • [Cites] Nature. 2002 Aug 22;418(6900):880-4 [12192411.001]
  • [Cites] Science. 2002 Dec 20;298(5602):2385-7 [12446832.001]
  • [Cites] Science. 2002 Dec 20;298(5602):2339-40 [12493901.001]
  • [Cites] J Biol Inorg Chem. 2003 Sep;8(7):787-801 [12898323.001]
  • [Cites] Nature. 2003 Oct 2;425(6957):531-5 [14523450.001]
  • [Cites] Crit Rev Biochem Mol Biol. 2004 Jan-Feb;39(1):21-68 [15121720.001]
  • [Cites] J Biol Chem. 2004 May 14;279(20):21394-400 [15026411.001]
  • [Cites] J Biol Chem. 2004 May 21;279(21):22284-93 [14985369.001]
  • [Cites] Antioxid Redox Signal. 2004 Oct;6(5):819-24 [15345141.001]
  • [Cites] Nat Struct Mol Biol. 2008 Apr;15(4):403-10 [18345016.001]
  • [Cites] Biochemistry. 2009 Feb 10;48(5):817-9 [19187031.001]
  • [Cites] Physiology (Bethesda). 2009 Feb;24:26-35 [19196649.001]
  • [Cites] Cell Mol Life Sci. 2009 Mar;66(5):852-75 [19099186.001]
  • [Cites] Adv Exp Med Biol. 2009;648:49-56 [19536464.001]
  • [Cites] J Biol Chem. 2009 Jul 31;284(31):20556-61 [19473966.001]
  • [Cites] Anal Biochem. 1987 Feb 15;161(1):1-15 [3578775.001]
  • [Cites] Blood. 1988 Jun;71(6):1755-8 [3370319.001]
  • [Cites] Science. 1988 Jul 29;241(4865):580-2 [2456613.001]
  • [Cites] Neuron. 1992 Aug;9(2):209-16 [1497890.001]
  • [Cites] J Biol Chem. 1992 Nov 15;267(32):22843-52 [1429633.001]
  • [Cites] Adv Exp Med Biol. 1996;410:97-103 [9030284.001]
  • [Cites] Nature. 1997 Jun 19;387(6635):827-30 [9194566.001]
  • [Cites] J Bacteriol. 1998 Jul;180(13):3491-4 [9642210.001]
  • [Cites] J Biol Chem. 1998 Sep 4;273(36):23426-32 [9722578.001]
  • [Cites] Biochim Biophys Acta. 1999 Mar 8;1449(2):125-36 [10082971.001]
  • [Cites] J Clin Invest. 1999 Sep;104(5):577-88 [10487772.001]
  • [Cites] Arch Biochem Biophys. 1958 Apr;74(2):443-50 [13534673.001]
  • [Cites] Science. 2004 Dec 17;306(5704):2093-7 [15528406.001]
  • [Cites] J Biol Inorg Chem. 2005 Mar;10(2):87-93 [15739104.001]
  • [Cites] J Gen Physiol. 2005 Jul;126(1):7-21 [15955873.001]
  • [Cites] Circ Res. 2005 Oct 14;97(8):805-12 [16166559.001]
  • [Cites] J Biol Chem. 2005 Dec 16;280(50):41716-24 [16227203.001]
  • [Cites] Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1761-6 [16356137.001]
  • [Cites] J Physiol. 2006 Jan 1;570(Pt 1):65-72 [16239267.001]
  • [Cites] Annu Rev Pharmacol Toxicol. 2006;46:411-49 [16402911.001]
  • [Cites] Biochem Biophys Res Commun. 2006 Apr 21;342(4):1389-95 [16516848.001]
  • [Cites] Nat Rev Neurosci. 2006 Dec;7(12):921-31 [17115074.001]
  • [Cites] J Biol Chem. 2007 Jul 20;282(29):21056-67 [17540772.001]
  • [Cites] Essays Biochem. 2007;43:43-60 [17705792.001]
  • [Cites] Hypertension. 2007 Oct;50(4):643-51 [17724275.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):376-81 [18162557.001]
  • [Cites] Science. 2001 Feb 16;291(5507):1304-51 [11181995.001]
  • (PMID = 20427280.001).
  • [ISSN] 1083-351X
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL102662; United States / NHLBI NIH HHS / HL / R21 HL089837; United States / NHLBI NIH HHS / HL / R21HL089837
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Disulfides; 0 / Ferric Compounds; 0 / Ferrous Compounds; 0 / KCNMA1 protein, human; 0 / Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; 0 / Sulfhydryl Compounds; 42VZT0U6YR / Heme; 7U1EE4V452 / Carbon Monoxide; EC 1.14.99.3 / Heme Oxygenase (Decyclizing); EC 1.14.99.3 / heme oxygenase-2; K848JZ4886 / Cysteine
  • [Other-IDs] NLM/ PMC2888424
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94. Dallas ML, Scragg JL, Wyatt CN, Ross F, Hardie DG, Evans AM, Peers C: Modulation of O(2) sensitive K (+) channels by AMP-activated protein kinase. Adv Exp Med Biol; 2009;648:57-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hypoxic inhibition of K(+) channels in type I cells is believed to be of central importance in carotid body chemotransduction.
  • Here, we have further explored the modulation by AMPK of recombinant K(+) channels (expressed in HEK293 cells) whose native counterparts are considered O(2)-sensitive in the rat carotid body.
  • These data highlight a role for AMPK in the modulation of two proposed O(2) sensitive K(+) channels found in the carotid body.

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  • (PMID = 19536465.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / KCNK9 protein, human; 0 / Large-Conductance Calcium-Activated Potassium Channels; 0 / Potassium Channel Blockers; 0 / Potassium Channels; 0 / Potassium Channels, Tandem Pore Domain; 0 / Ribonucleotides; 360-97-4 / Aminoimidazole Carboxamide; EC 2.7.11.1 / AMP-Activated Protein Kinases; F0X88YW0YK / AICA ribonucleotide; S88TT14065 / Oxygen
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95. Sunar H, Keles C, Besirli K: Elective shunt use for easy resection of a carotid body tumor. Vascular; 2008 Jan-Feb;16(1):41-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Elective shunt use for easy resection of a carotid body tumor.
  • Carotid body tumor resection has the potential hazards of hemorrhage, cranial nerve palsy, and cerebrovascular accident.
  • The control of intraoperative bleeding during manipulation of the tumor is a critical issue for safe resection.
  • In the presented case with a carotid body tumor, the Shamblin II, a carotid shunt with a dual balloon was used electively.
  • The aim of shunt use was partial isolation of the tumor from carotid arterial circulation in a short time only.
  • [MeSH-major] Carotid Body Tumor / surgery. Head and Neck Neoplasms / surgery
  • [MeSH-minor] Adult. Blood Loss, Surgical / prevention & control. Carotid Artery, Common / surgery. Female. Humans. Magnetic Resonance Angiography. Prostheses and Implants

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  • (PMID = 18258162.001).
  • [ISSN] 1708-5381
  • [Journal-full-title] Vascular
  • [ISO-abbreviation] Vascular
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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96. Wolf MB, Garner RP: A mathematical model of human respiration at altitude. Ann Biomed Eng; 2007 Nov;35(11):2003-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The peripheral response has both a linear term similar to that for the central chemoceptors, but dependent upon carotid body P(CO2) and with a different threshold and a complex, nonlinear term that includes multiplication of separate terms involving carotid body P(O2) and P(CO2).

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  • (PMID = 17674206.001).
  • [ISSN] 0090-6964
  • [Journal-full-title] Annals of biomedical engineering
  • [ISO-abbreviation] Ann Biomed Eng
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Ghoreishi M, Akbar-Beigi A, Tahery D, Sehhat S: Fever as the main presenting symptom of a carotid body tumor. Arch Iran Med; 2008 Mar;11(2):214-7
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  • [Title] Fever as the main presenting symptom of a carotid body tumor.
  • Carotid body tumor (paraganglioma) is a rare tumor which presents as a mass in the lateral part of the neck.
  • Fever is not an usual symptom of this tumor.
  • Here, we report a 78- year-old woman presenting with this tumor as a cause of fever of unknown origin.
  • [MeSH-major] Carotid Body Tumor / diagnosis. Fever / diagnosis
  • [MeSH-minor] Aged. Angiography, Digital Subtraction. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 18298303.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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98. Gauda EB, Carroll JL, Donnelly DF: Developmental maturation of chemosensitivity to hypoxia of peripheral arterial chemoreceptors--invited article. Adv Exp Med Biol; 2009;648:243-55
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  • Peripheral arterial chemoreceptors, particularly the carotid body chemoreceptors, are the primary sites for the detection of hypoxia and reflexly increase ventilatory drive and behavioral arousal during hypoxic or asphyxial events.
  • This review summarizes the available data showing that even though the "oxygen sensor" in the glomus cells has not been unequivocally identified, it is clear that development affects many of the other properties of the chemoreceptor unit (glomus cell, afferent nerve fibers and neurotransmitter profile at the synapse) that are necessary and essential for the propagation of the "sensing" response, and exposure to hypoxia, hyperoxia and nicotine can modify normal development of each of the components leading to altered peripheral chemoreceptor responses.
  • [MeSH-minor] Animals. Carotid Body / metabolism. Humans. Neurotransmitter Agents / metabolism

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  • (PMID = 19536487.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01HL80735; United States / NHLBI NIH HHS / HL / R21HL082860-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neurotransmitter Agents
  • [Number-of-references] 52
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99. Lehmen JA, Babbel DM, Mikhitarian K, Choma TJ: Paraganglioma presenting as metastatic lesion in a cervical vertebra: a case report and review of the literature. Spine (Phila Pa 1976); 2010 Mar 1;35(5):E152-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To discuss the spinal presentation and treatment of paraganglioma, a rare tumor of the extra-adrenal paraganglia, derived from neural crest cells in sympathetic ganglions.
  • The diagnosis of malignant paraganglioma is made by local recurrence after total resection of the primary mass, or findings of distant metastases.
  • The patient had a previous carotid body tumor resection in the past and a contralateral carotid body tumor left intact.
  • Our imaging workup, including plain radiograph, computerized tomography scan and MRI, revealed an intraosseous lesion at C6 with vertebral body destruction.
  • [MeSH-major] Cervical Vertebrae. Neck Pain / etiology. Paraganglioma / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Decompression, Surgical. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • (PMID = 20118832.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Iturriaga R, Moya EA, Del Rio R: Carotid body potentiation induced by intermittent hypoxia: implications for cardiorespiratory changes induced by sleep apnoea. Clin Exp Pharmacol Physiol; 2009 Dec;36(12):1197-204
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carotid body potentiation induced by intermittent hypoxia: implications for cardiorespiratory changes induced by sleep apnoea.
  • The OSA syndrome is a highly prevalent sleep breathing disorder that is considered an independent risk factor for hypertension and cardiovascular diseases.
  • 2. Because OSA patients and animals exposed to CIH show augmented ventilatory, sympathetic and cardiovascular responses to acute hypoxia, it has been proposed that enhanced carotid body responsiveness to hypoxia is involved in the autonomic changes induced by OSA and in the development of the hypertension.
  • Recently, this proposal has received further support from recordings of carotid body chemosensory neural discharges in situ and in vitro showing that exposure of animals to CIH increases basal carotid body chemosensory discharges and enhances the chemosensory response to hypoxia.
  • 3. In the present brief review, we discuss the evidence supporting an important role for the carotid body in the progression of cardiorespiratory changes induced by OSA and the contribution of oxidative stress, endothelin-1 and pro-inflammatory molecules in the potentiation of the carotid body chemosensory function induced by CIH.
  • [MeSH-major] Anoxia / physiopathology. Cardiovascular System / physiopathology. Carotid Body / physiopathology. Respiratory System / physiopathology. Sleep Apnea, Obstructive / physiopathology

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  • (PMID = 19473190.001).
  • [ISSN] 1440-1681
  • [Journal-full-title] Clinical and experimental pharmacology & physiology
  • [ISO-abbreviation] Clin. Exp. Pharmacol. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Endothelin-1; 0 / Inflammation Mediators
  • [Number-of-references] 57
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