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6. Azorín D, González-Mediero I, Colmenero I, De Prada I, López-Barea F: Diaphyseal chondroblastoma in a long bone: first report. Skeletal Radiol; 2006 Jan;35(1):49-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diaphyseal chondroblastoma in a long bone: first report.
  • Chondroblastoma is a rare benign bone tumor typically located in the epiphysis.
  • We describe the first case of chondroblastoma arising in the diaphysis of a long bone.

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  • (PMID = 16010594.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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7. Toy PC, White JR, Scarborough MT, Enneking WF, Gibbs CP: Distal femoral osteoarticular allografts: long-term survival, but frequent complications. Clin Orthop Relat Res; 2010 Nov;468(11):2914-23
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  • METHODS: We retrospectively reviewed 26 patients who had osteoarticular allograft reconstruction of the distal femur after resection of a malignant or aggressive benign tumor of bone.
  • Lacking the benefit of improved soft tissue attachments inherent in other anatomic sites, we believe this option is most appropriate for restoring bone stock in young patients with expectations of long-term survival.
  • [MeSH-major] Bone Transplantation / adverse effects. Femoral Neoplasms / surgery. Femur / surgery. Graft Survival
  • [MeSH-minor] Adolescent. Adult. Amputation. Child. Female. Humans. Kaplan-Meier Estimate. Limb Salvage. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Recovery of Function. Reoperation. Retrospective Studies. Time Factors. Transplantation, Homologous. Treatment Outcome. Young Adult

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  • (PMID = 20645036.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2947705
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8. Weber KL, Peabody T, Frassica FJ, Mott MP, Parsons TW 3rd: Tumors for the general orthopedist: how to save your patients and practice. Instr Course Lect; 2010;59:579-91
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  • [Title] Tumors for the general orthopedist: how to save your patients and practice.
  • It is likely that most orthopaedic surgeons will see a patient with a benign or malignant musculoskeletal tumor sometime during their career.
  • However, because of the rarity of these entities, many surgeons may benefit from a review of how to evaluate a patient with a bone lesion or soft-tissue mass.
  • A logical approach is necessary in evaluating imaging studies as well as in the workup of children and adults with a possible tumor.
  • If the treatment algorithms lead to a conclusive diagnosis of a benign bone tumor, benign soft-tissue mass, or metastatic bone disease, the orthopaedic surgeon may choose to definitively treat the patient.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Cysts / diagnosis. Joint Diseases / pathology. Orthopedics. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 20415407.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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9. Cueva del Castillo JF, Francisco Osuna J, Elizondo F, Pérez O, Pérez A, Hernández S, Mejía C: [Use of a xenoimplant for the treatment of bone defects, benign tumors, pseudoarthrosis and arthrodesis. Preliminary report]. Acta Ortop Mex; 2007 Jan-Feb;21(1):31-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Use of a xenoimplant for the treatment of bone defects, benign tumors, pseudoarthrosis and arthrodesis. Preliminary report].
  • [Transliterated title] Aplicación de xenoimplante para el tratamiento de defectos oseos, tumores benignos, seudoartrosis y artrodesis. (Reporte preliminar).
  • OBJECTIVE: To show that the ceramic produced at the Institute for Materials Research, National Autonomous University of Mexico, is an appropriate replacement of bone graft in patients with bone tumors, benign tumors, pseudoarthrosis and arthrodesis treated at "General Ignacio Zaragoza" Regional Hospital.
  • They underwent X-ray evaluation of bone healing using the Montoya classification.
  • The most frequent indication was arthrodesis in 10 patients (45.45%), pseudoarthrosis in 6 (27.27%), benign tumors in 3 (13.63%), and bone defects in 3 (13.63%).
  • Type II to type IV bone healing was observed in the sample.
  • DISCUSSION: The use of ceramic xenoimplants is appropriate as a replacement of bone graft in patients with arthrodesis and bone defects, thus avoiding the need for autologous bone graft.
  • [MeSH-major] Arthrodesis. Bone Neoplasms / surgery. Bone Transplantation. Pseudarthrosis / surgery. Transplantation, Heterologous

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  • (PMID = 17695206.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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10. Miyake A, Morioka H, Yabe H, Anazawa U, Morii T, Miura K, Mukai M, Takayama S, Toyama Y: A case of metacarpal chondrosarcoma of the thumb. Arch Orthop Trauma Surg; 2006 Aug;126(6):406-10
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  • Enchondroma is the most common primary benign bone tumor of the hand.
  • It often is difficult to make a histological distinction between benign cartilaginous tumors and low-grade chondrosarcomas, because enchondromas at this site often show histological features suggestive of malignancy.
  • This is a case report of chondrosarcoma affecting the metacarcal bone of the thumb, treated by en block resection and preserving the function of the thumb by bone graft reconstruction, with reference to the literature.
  • [MeSH-major] Bone Neoplasms / surgery. Chondrosarcoma / surgery. Metacarpal Bones

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  • (PMID = 16557368.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Atalar B, Miller RC, Dincbas FO, Geismar JH, Micke O, Akyurek S, Ozyar E: Adult langerhans cell histiocytosis of bones : a rare cancer network study. Acta Orthop Belg; 2010 Oct;76(5):663-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Langerhans Cell Histiocytosis (LCH) is an uncommon benign bone tumour typically seen in children.
  • The localization of tumours was skull bones in 12 (40%), lower extremity in 6 (20%), thoracic bones in 4 (133%), spine in 3 (10%), pelvis in 2 (6.7%) and multiple sites in 3 (10%) patients.
  • [MeSH-major] Bone Diseases / therapy. Histiocytosis, Langerhans-Cell / therapy


12. Kumar A, Varshney MK, Trikha V, Rastogi S: An unusual presentation of a rare chest wall tumour: giant cell tumour of bone. Joint Bone Spine; 2007 Jan;74(1):100-2
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  • [Title] An unusual presentation of a rare chest wall tumour: giant cell tumour of bone.
  • Giant cell tumour of bone is an aggressive benign bone tumour.
  • We report a case of giant cell tumour of the anterior end of the rib masquerading as a sub-mammary abscess in lactating women.
  • [MeSH-major] Bone Neoplasms / diagnosis. Giant Cell Tumor of Bone / diagnosis. Thoracic Wall
  • [MeSH-minor] Abscess / diagnosis. Adult. Diagnosis, Differential. Female. Humans. Lactation. Treatment Outcome

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  • (PMID = 17197221.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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13. Chen YR, Chang CN, Tan YC: Craniofacial fibrous dysplasia: an update. Chang Gung Med J; 2006 Nov-Dec;29(6):543-9
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  • Fibrous dysplasia was first described by Lichtenstein in 1938 as a disorder characterized by progressive replacement of normal bone elements by fibrous tissue.
  • It is a bone tumor that, although benign, has the potential to cause significant cosmetic and functional disturbance, particularly in the craniofacial skeleton.

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  • (PMID = 17302216.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China (Republic : 1949- )
  • [Number-of-references] 50
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4. Prado MP, Mendes AA, Amodio DT: Benign bone tumors subperiosteal on the talar neck resected anthroscopically: case reports. Einstein (Sao Paulo); 2010 Sep;8(3):354-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign bone tumors subperiosteal on the talar neck resected anthroscopically: case reports.
  • Two cases of benign chondral tumors of the talar neck region (an osteoid osteoma and a chondroblastoma) were described.

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  • (PMID = 26760154.001).
  • [ISSN] 1679-4508
  • [Journal-full-title] Einstein (São Paulo, Brazil)
  • [ISO-abbreviation] Einstein (Sao Paulo)
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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15. Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M: Osteochondromas: review of the clinical, radiological and pathological features. In Vivo; 2008 Sep-Oct;22(5):633-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones.
  • This tumor takes the form of a cartilage-capped bony outgrowth on the surface of the bone.
  • Approximately 15% of osteochondromas occur as multiple lesions in the context of hereditary multiple osteochondromas (HMOs), a disorder that is inherited in an autosomal dominant manner.
  • [MeSH-major] Bone Neoplasms / pathology. Bone Neoplasms / radiography. Osteochondroma / pathology. Osteochondroma / radiography

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  • (PMID = 18853760.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
  • [Number-of-references] 125
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16. Tanigawa N, Kariya S, Kojima H, Komemushi A, Fujii H, Sawada S: Lower limb ischaemia caused by fractured osteochondroma of the femur. Br J Radiol; 2007 Apr;80(952):e78-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteochondroma is the most common benign bone tumour and can arise in any bone.
  • [MeSH-major] Bone Neoplasms / complications. Exostoses, Multiple Hereditary / complications. Femoral Fractures / complications. Ischemia / etiology. Leg / blood supply


17. Stegger L, Juergens KU, Kliesch S, Wormanns D, Weckesser M: Unexpected finding of elevated glucose uptake in fibrous dysplasia mimicking malignancy: contradicting metabolism and morphology in combined PET/CT. Eur Radiol; 2007 Jul;17(7):1784-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fibrous dysplasia is a common benign disorder of bone in which fibro-osseous tissue replaces bone spongiosa.
  • Lesions have a typical appearance on computed tomography (CT) images and regularly show a markedly increased uptake in bone scintigraphy using (99m)Tc-labelled methylene diphosphonate ((99m)Tc-MDP) as radiotracer.
  • [MeSH-major] Blood Glucose / metabolism. Fibrous Dysplasia, Polyostotic / diagnosis. Image Processing, Computer-Assisted. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Carcinoma, Embryonal / diagnosis. Carcinoma, Embryonal / drug therapy. Carcinoma, Embryonal / secondary. Carcinoma, Embryonal / surgery. Combined Modality Therapy. Diagnosis, Differential. Femoral Neoplasms / diagnosis. Femoral Neoplasms / secondary. Fluorodeoxyglucose F18. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Postoperative Complications / diagnosis. Sensitivity and Specificity. Testicular Neoplasms / diagnosis. Testicular Neoplasms / drug therapy. Testicular Neoplasms / surgery

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  • (PMID = 17066288.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Blood Glucose; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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18. Abula A, Abaiyedula A, Yusufu A, Liu C, Huang H: [Preliminary clinical application of cancellous granule-type calcium phosphate cement]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2010 Sep;24(9):1100-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To investigate the clinical efficacy of the cancellous granule-type calcium phosphate cement in repair bone defect.
  • METHODS: Between July 2008 and July 2009, 35 patients (42 limbs) with fractures, nonunion, and benign bone tumor were treated with cancellous granule-type calcium phosphate cement.
  • There were 32 males and 3 females, with an age range from 9 to 73 years (median, 41 years), including 24 limb fractures (19 cases), 4 osteotomy for deformity of ulna and radius (2 cases), 2 femur intertrochanteric bony cysts (2 cases), 3 enchondroma (3 cases), 5 bone defect at donor ilium (5 cases), 3 nonunion (3 cases), and 1 lumbar spinal stenosis (1 case).
  • The size of bone defect was 1-5 cm.
  • Bone defect was repaired with cancellous granule-type calcium phosphate cement (1-5 g).
  • Incision dehiscence occurred in 2 cases, and wounds healed after second debridement and removal of artificial bone.
  • X-ray films showed that bone graft fusion was achieved and bone defect was radically repaired at 6 months after operation and artificial bone was absorbed completely at 12 months.
  • CONCLUSION: Cancellous granule-type calcium phosphate cement can be used as a new graft bone material, which is suitable for defect filling after traumatic fracture, benign bone tumors, and iliac bone donor.
  • [MeSH-major] Bone Cements. Bone Transplantation / instrumentation. Calcium Phosphates / therapeutic use

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  • (PMID = 20939483.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Bone Cements; 0 / Calcium Phosphates; 97Z1WI3NDX / calcium phosphate
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19. Jonathan A, Rajshekhar V, Chacko G: Chondromyxoid fibroma of the seventh cervical vertebra. Neurol India; 2008 Jan-Mar;56(1):84-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondromyxoid fibroma is a rare benign bone tumor representing less than 0.5% of all bone tumors.
  • A presumptive diagnosis of a bony tumor such as an aneurysmal bone cyst or a giant cell tumor involving the seventh vertebral body was made on plain X-rays, MRI and bone scan.
  • He underwent C7 central corpectomy, incomplete intralesional curettage with iliac bone grafting and C6 to T1 interspinous wiring.
  • The histological diagnosis was chondromyxoid fibroma.
  • On eight years' follow-up, CT scan showed no progression of the tumor with good alignment and fusion of the graft at the site of the corpectomy.
  • The authors conclude that corpectomy and iliac bone grafting for chondromyxoid fibroma has a good outcome on long-term follow-up.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / pathology. Cervical Vertebrae / pathology. Chondromatosis / complications. Fibroma / complications. Fibroma / pathology

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  • (PMID = 18310848.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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20. Yoshioka K, Nagata R, Ueda M, Yamaguchi T, Konishi Y, Hosoi M, Inoue T, Yamanaka K, Iwai Y, Sato T: Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy. Intern Med; 2006;45(20):1157-60
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  • [Title] Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy.
  • A 45-year-old man was admitted to our hospital because of bone pain and hypophosphatemia.
  • He had undergone surgery 2 years previously for a "benign unclassified mesenchymal tumor" in the skull, but there were no clinical symptoms related to osteomalacia.
  • The diagnosis of tumor-induced osteomalacia due to phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) was made by re-examining the pathologic specimens.
  • Clinicians and pathologists should be aware of the existence of PMTMCT especially nonphosphaturic or asymptomatic variants of this disorder.
  • [MeSH-minor] Fractures, Spontaneous / etiology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / complications. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Octreotide / administration & dosage. Octreotide / therapeutic use. Phosphates / therapeutic use. Radiosurgery. Vitamin D / analogs & derivatives. Vitamin D / therapeutic use

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  • (PMID = 17106161.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Phosphates; 1406-16-2 / Vitamin D; 66772-14-3 / 1,25-dihydroxyvitamin D; RWM8CCW8GP / Octreotide
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21. Fukunaga S, Futani H, Yoshiya S: Endoscopically assisted resection of a scapular osteochondroma causing snapping scapula syndrome. World J Surg Oncol; 2007;5:37
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  • BACKGROUND: Osteochondroma is the most common benign bone tumor in the scapula.
  • Removal of the tumor was performed by the use of endoscopically assisted resection.
  • The tumor was resected in a piece-by-piece manner by the use of graspers through the same portal.
  • CT images showed complete tumor resection.
  • [MeSH-major] Bone Neoplasms / surgery. Endoscopy. Osteochondroma / surgery. Scapula

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  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
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22. Bostan B, Sen C, Gunes T, Erdem M, Koseoglu RD: Osteoid osteoma of the trapezium: case report. J Hand Surg Am; 2010 Apr;35(4):636-8
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  • Osteoid osteoma is a benign bone tumor representing approximately 10% of all benign bone tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Osteoma, Osteoid / diagnosis. Trapezium Bone / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Diagnostic Imaging. Humans. Male

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  • (PMID = 20171814.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Mir NA, Baba AN, Maajid S, Badoo AR, Mir GR: Osteoblastoma of body of the talus--Report of a rare case with atypical radiological features. Foot Ankle Surg; 2010 Jun;16(2):e24-6
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  • Osteoblastoma is a benign bone tumour found commonly in the spine and long tubular bones.
  • Analysis of clinical, radiological and histological findings confirmed the diagnosis of osteoblastoma.
  • [MeSH-major] Bone Neoplasms / radiography. Osteoblastoma / radiography. Rare Diseases. Talus. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Osteotomy / methods

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  • [Copyright] Copyright 2009 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20483122.001).
  • [ISSN] 1460-9584
  • [Journal-full-title] Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
  • [ISO-abbreviation] Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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24. Jundt G, Baumhoer D: [Hereditary bone tumors]. Pathologe; 2010 Oct;31(6):471-6
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  • [Title] [Hereditary bone tumors].
  • Familial diseases leading to bone tumor formation are rare.
  • This leads to multiple benign bone tumors, which may undergo secondary malignant transformation (enchondromatosis: enchondromas, multiple hereditary exostoses: osteochondromas) or bone sarcomas, mainly osteosarcomas, such as primary (Li-Fraumeni, Rothmund-Thomson, Werner and Bloom syndromes) or secondary manifestations (retinoblastoma syndrome) of the underlying disease.
  • In contrast to sporadically occurring similar tumors, differences in manifestation in time, topography or histology may be present which can aid in the correct recognition of the underlying syndrome.
  • [MeSH-major] Bone Neoplasms / genetics

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  • (PMID = 20960198.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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25. Dierselhuis EF, Jutte PC, van der Eerden PJ, Suurmeijer AJ, Bulstra SK: Hip fracture after radiofrequency ablation therapy for bone tumors: two case reports. Skeletal Radiol; 2010 Nov;39(11):1139-43
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  • [Title] Hip fracture after radiofrequency ablation therapy for bone tumors: two case reports.
  • In orthopedic surgery, RFA is used for the treatment of benign bone tumors and bone metastases.
  • Complications are rare and, to our knowledge, bone fracture as a complication due solely to RFA has not been reported to date.
  • In this report we describe two patients with a fracture in the calcar region of the femur as a complication of RFA treatment for bone malignancies.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Catheter Ablation / adverse effects. Femoral Fractures / diagnosis. Femoral Fractures / etiology. Magnetic Resonance Imaging. Tomography, X-Ray Computed


26. Li Y, Liang Q, Wen YQ, Chen LL, Wang LT, Liu YL, Luo CQ, Liang HZ, Li MT, Li Z: Comparative proteomics analysis of human osteosarcomas and benign tumor of bone. Cancer Genet Cytogenet; 2010 Apr 15;198(2):97-106
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  • [Title] Comparative proteomics analysis of human osteosarcomas and benign tumor of bone.
  • Proteins extracted from osteosarcoma tissue and benign bone tumors, including osteoblastoma, chondroblastoma, and giant cell tumor of bone, were examined using two-dimensional gel electrophoresis followed by mass spectrometry analysis and database searches.
  • Aberrant expression of cytoskeletal- and microtubule-associated proteins in osteosarcoma may provide an advantage for tumor invasion and metastasis by affecting the stability of microtubule, which consequently influences the prognosis of patients.
  • [MeSH-major] Bone Neoplasms / metabolism. Neoplasm Proteins / analysis. Osteoblastoma / metabolism. Osteosarcoma / metabolism. Proteomics / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Bone and Bones / metabolism. Bone and Bones / pathology. Child. Chondroblastoma / metabolism. Chondroblastoma / pathology. Female. Giant Cell Tumor of Bone / metabolism. Giant Cell Tumor of Bone / pathology. Humans. Male. Middle Aged. Proteome / analysis. Proteome / metabolism. Young Adult


27. Angiero F, Mellone P, Baldi A, Stefani M: Osteoblastoma of the jaw: report of two cases and review of the literature. In Vivo; 2006 Sep-Oct;20(5):665-70
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  • Osteoblastoma is a benign bone tumor of osteoblastic origin.
  • Both tumors were resected with wide surgical margins and neither patient had adjuvant radiation or chemotherapy.
  • Differential diagnosis and immunohistochemical features potentially useful for refining diagnosis of osteoblastoma are also discussed.
  • [MeSH-major] Biomarkers, Tumor / analysis. Jaw Neoplasms / pathology. Osteoblastoma / pathology

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  • (PMID = 17091775.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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28. Poffyn B, Sys G, Van Maele G, Van Hoorebeke L, Forsyth R, Verstraete K, Uyttendaele D: Radiographic analysis of extracorporeally irradiated autografts. Skeletal Radiol; 2010 Oct;39(10):999-1008
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  • OBJECTIVE: To analyse the long-term radiographic findings of intercalary, pure osteoarticular, and composite bone grafts in patients with primary bone sarcoma who were treated by reimplantation of the bone as an orthotopic autograft.
  • MATERIALS AND METHODS: For this observational clinical study, 107 patients who presented with 108 malignant or locally aggressive benign bone tumours were treated by resection, extracorporeal irradiation (300 Gy), and reimplantation and fixation of the autograft.
  • Bone healing features were evaluated with the International Society of Limb Salvage (ISOLS) graft evaluation method, which assesses fusion, resorption, fracture, graft shortening, fixation, subluxation, joint narrowing, and subchondral bone.
  • CONCLUSION: This reconstruction technique is valid for the three methods described; bone stock is retained and, once the graft has healed, it behaves as normal bone.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / diagnostic imaging. Bone Transplantation / methods. Sarcoma / surgery

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  • (PMID = 20703876.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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29. Ortakoglu K, Akcam T, Sencimen M, Karakoc O, Ozyigit HA, Bengi O: Osteochondroma of the mandible causing severe facial asymmetry: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 May;103(5):e21-8
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  • Osteochondroma is one of the most common benign tumors of bone.
  • The aim of the present study is to emphasize the importance of stereolithographic models in planning tumor surgery and how it affects the treatment planning, operation time and prognosis.
  • Based on the model evaluation, the tumor was conservatively resected and the condyle left intact, leaving no sequelae.

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  • (PMID = 17331758.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Lin SP, Fang YC, Chu DC, Chang YC, Hsu CI: Characteristics of cranial aneurysmal bone cyst on computed tomography and magnetic resonance imaging. J Formos Med Assoc; 2007 Mar;106(3):255-9
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  • [Title] Characteristics of cranial aneurysmal bone cyst on computed tomography and magnetic resonance imaging.
  • Aneurysmal bone cysts are benign bone tumors that most commonly occur in people younger than 30 years.
  • The tumor was soft, fragile, and pulsatile during surgery.
  • The patient was treated with en bloc resection of the tumor with cranioplasty.

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  • (PMID = 17389172.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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31. Fu K, Meng ZB, Li J, Li HC: [Repairing the defect of benign bone tumor with the coralline hydroxyapatite]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 May;33(5):421-4
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  • [Title] [Repairing the defect of benign bone tumor with the coralline hydroxyapatite].
  • OBJECTIVE: To observe the clinical effect of repairing bone defectin post-operation benign tumor with coralline hydroxyapatite(CHAP).
  • The CHAP was implanted into the lesion after bone tumor curettage to 25 patients.
  • The sizes of bone defect ranged from 0.8 cm x 0.5 cm x 0.5 cm to 10 cm x 3.5 cm x 2 cm.
  • X-ray showed that there was osteogenesis at the cortical bone 1 month post-operation.
  • There is corresponding synchronization between bone formation with CHAP biodegradation.
  • The CHAP is an excellent bone defect repairing material.
  • [MeSH-major] Bone Neoplasms / surgery. Ceramics. Giant Cell Tumor of Bone / surgery. Hydroxyapatites. Prostheses and Implants
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Cysts / surgery. Bone Regeneration. Bone Substitutes. Child. Female. Femur / surgery. Humans. Male. Middle Aged

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  • (PMID = 18544846.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Bone Substitutes; 0 / Hydroxyapatites; 0 / coralline hydroxyapatite
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32. Guo Z, Wang Z, Li J, Li XD: [Reconstruction with a new type of combined reconstruction following excision of periacetabular tumors]. Zhonghua Wai Ke Za Zhi; 2008 Jun 15;46(12):895-9
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  • [Title] [Reconstruction with a new type of combined reconstruction following excision of periacetabular tumors].
  • OBJECTIVE: To evaluate the reconstructive effect of a new pattern of combined reconstruction after periacetabular tumor resections.
  • METHODS: Between March 2001 and March 2007, tumor resections and new pattern of combined reconstructions which consisted of screw-rod system, acetabular reinforcement shell, antibiotic cement and total hip arthroplasty techniques were performed in 23 patients with periacetabular tumors.
  • Seventeen patients had primary malignant tumors including 7 chondrosarcomas, 4 osteosarcomas, 2 Ewing sarcomas, 2 malignant fibrohistiocytomas, 1 malignant Schwannomas, and 1 synovial sarcoma.
  • Other primary tumors were 2 giant cell tumors and 1 aggressive osteoblastoma.
  • Three metastatic bone tumors were also included in this study, and the original sites were thyroid, breast, and ovary.
  • Three primary benign bone tumors belonged to stage III.
  • 8 months (range, 9-73 months) in the patients with primary tumors.
  • CONCLUSIONS: This new combined reconstruction is an effective way to rebuild pelvic ring and maintain hip function with low complication rate after periacetabular tumor resections.
  • [MeSH-major] Acetabulum. Bone Neoplasms / surgery. Reconstructive Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Arthroplasty, Replacement, Hip. Bone Screws. Female. Follow-Up Studies. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 19035146.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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33. Rougraff BT: Bone graft alternatives in the treatment of benign bone tumors. Instr Course Lect; 2005;54:505-12
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  • [Title] Bone graft alternatives in the treatment of benign bone tumors.
  • Most bone grafting procedures are done during spinal fusion and to treat patients with skeletal trauma.
  • Very few studies have addressed the bone grafting of skeletal defects after benign bone tumor excision.
  • Contained defects have been treated with autogenous bone grafts, fresh-frozen allografts, freeze-dried allografts, demineralized bone matrix, and ceramic materials.
  • Additionally, bone morphogenetic proteins may provide a future treatment option for bone tumor reconstruction.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / methods
  • [MeSH-minor] Bone Substitutes. Ceramics. Humans. Tissue Preservation / methods. Transplantation, Homologous

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  • (PMID = 15948475.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Substitutes
  • [Number-of-references] 30
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34. Park YK, Kim EJ, Kim SW: Osteoblastoma of the ethmoid sinus. Skeletal Radiol; 2007 May;36(5):463-7
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  • An osteoblastoma is a benign bone tumor that most often occurs in the vertebral column and the long bones of the extremities.
  • A mixture of ground glass opacity and dense bone was present.
  • Histologically, the lesion was composed of proliferating osteoblasts along with small trabeculae of woven bone and rich vascular fibrous stroma.
  • [MeSH-major] Ethmoid Sinus / pathology. Ethmoid Sinus / surgery. Osteoblastoma / diagnosis. Osteoblastoma / surgery. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 17265159.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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35. Liang X, Jiang D, Ni W: [Clinical observation on nano-hydroxyapatite and polyamide 66 composite in repairing bone defect due to benign bone tumor]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2007 Aug;21(8):785-8
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  • [Title] [Clinical observation on nano-hydroxyapatite and polyamide 66 composite in repairing bone defect due to benign bone tumor].
  • OBJECTIVE: To observe the clinical effect and safety of the nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite in repairing the bone defects due to benign bone tumors.
  • METHODS: From January 2003 to May 2005, 38 patients (21 males, 16 females; age, 19-58 years, averaged 38.5 years) with the bone defects due to benign bone tumors were treated with the n-HA/PA66 grains.
  • Among the 37 patients, 11 had fibrous dysplasia, 14 had bone cyst, 10 had giant cell tumor of the bone (Grade I ), and 2 had enchondroma.
  • The tumors ranged in size from 1.0 cm x 0.7 cm x 0.4 cm to 10.0 cm x 4.0 cm x 3.0 cm, with the location of the proximal femur in 12 patients, the distal femur in 7, the proximal tibia in 9, the proximal humerus in 5, the phalanges of the finger in 2, the metacarpal bone in 1, and the calcaneus in 1.
  • All the benign bone tumors underwent the curettage treatment, and then the tumor cavities were filled up with the n-HA/PA66 grains.
  • The incision healing, local inflammatory reaction, rejection, toxic reaction, tumor cavity healing, and function recovery of the limbs were all observed after operation.
  • At 3 to 5.5 months(mean 4 months) after operation, osteogenesis was found in the space filled with the n-HA/PA66 grains.
  • CONCLUSION: The n-HA/PA66 grains have great biological safety, good biocompatibility, and good bone conduction, which are good materials for the bone repair and reconstruction, and can be safely, and effectively used for repairing the bone defects due to benign bone tumors.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Substitutes. Hydroxyapatites. Nylons
  • [MeSH-minor] Adult. Biocompatible Materials. Bone Cysts / surgery. Female. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Humans. Male. Middle Aged. Nanostructures. Reconstructive Surgical Procedures / methods. Treatment Outcome. Wound Healing. Young Adult

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  • (PMID = 17882867.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Bone Substitutes; 0 / Hydroxyapatites; 0 / Nylons
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36. Roy S, Dobson P, Henry L: An isolated osteochondroma with underlying non-Hodgkin's lymphoma of bone. J Bone Joint Surg Br; 2005 Oct;87(10):1423-4
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  • [Title] An isolated osteochondroma with underlying non-Hodgkin's lymphoma of bone.
  • Osteochondroma is the most common benign bone tumour.
  • We report a case of an isolated osteochondroma which appeared benign on clinical and plain radiographic examination but routine histological analysis revealed non-Hodgkin's lymphoma in the underlying bone.
  • This association has not previously been reported and the case emphasises the importance of routine histological analysis, even if a lesion appears benign.
  • [MeSH-major] Bone Neoplasms / pathology. Lymphoma, Large B-Cell, Diffuse / pathology. Neoplasms, Multiple Primary / pathology. Osteochondroma / pathology

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  • (PMID = 16189321.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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37. Abolghasemian M, Rezaie M, Behgoo A, Shoushtarizadeh T, Ghazavi MT: Exostosis-like intra-articular periosteal osteoblastoma: a rare case. Am J Orthop (Belle Mead NJ); 2010 Jun;39(6):E50-3
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  • Osteoblastoma is a relatively rare benign bone tumor, most often located in the vertebral column or metaphysis of the long bones, particularly the femur and the tibia.
  • Exostosis-like appearance is not common even in periosteal osteoblastoma, a very rare type of this tumor.
  • [MeSH-major] Bone Neoplasms / pathology. Hip Joint / pathology. Osteoblastoma / pathology. Periosteum / pathology

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  • (PMID = 20631934.001).
  • [ISSN] 1934-3418
  • [Journal-full-title] American journal of orthopedics (Belle Mead, N.J.)
  • [ISO-abbreviation] Am J. Orthop.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Blackwell JB, Curnow MN: Benign bone tumours in Western Australia, 1972-1996. Pathology; 2007 Dec;39(6):567-74
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  • [Title] Benign bone tumours in Western Australia, 1972-1996.
  • AIMS: To review the benign bone tumours accessioned by the Bone Tumour Registry (BTR) of Western Australia (WA) during the years 1972-1996 and to determine the incidence of the more common types.
  • RESULTS: During the 25 year period, 849 benign tumours were accessioned and incidence rates have been calculated for 86 chondromas, 68 osteoid osteomas, 47 giant cell tumours, 32 chondroblastomas, 15 periosteal chondromas and 13 chondromyxoid fibromas.
  • CONCLUSION: The BTR provides a valuable resource for the study of primary bone tumours.
  • This review has established reliable incidence rates for the six most common benign tumours.
  • Such information is rarely available for benign tumours.
  • [MeSH-major] Bone Neoplasms / pathology. Registries
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local. Western Australia / epidemiology

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  • (PMID = 18027260.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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39. Moon IS, Kim J, Lee HK, Lee WS: Surgical treatment and outcomes of temporal bone chondroblastoma. Eur Arch Otorhinolaryngol; 2008 Dec;265(12):1447-54
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  • [Title] Surgical treatment and outcomes of temporal bone chondroblastoma.
  • Chondroblastoma is an uncommon primary benign bone tumor that usually arises in the epiphyses of the long bones.
  • Temporal bone chondroblastoma is a rare primary bone tumor that affects the floor of the middle cranial fossa and temporomandibular joint (TMJ).
  • The biological nature of temporal bone chondroblastoma is occasionally aggressive because of local invasion and is known to have a high recurrence after curettage.
  • The authors have retrospectively analyzed four cases of temporal bone chondroblastoma that had been completely excised by a single surgeon with an eventual long-term follow-up.
  • In all cases, the tumor involved the middle cranial fossa dura and the mandibular fossa with variable degree of infiltration.
  • All patients have had no tumor recurrence to date (mean follow-up period of 5 years).
  • Complete surgical resection of the temporal bone chondroblastoma is the gold standard for treatment.
  • Precise preoperative image evaluation of tumor extension and proper management of the dura mater and temporomandibular joint (TMJ) are the major important features in complete surgical removal that minimize complications in temporal bone chondroblastoma treatment.
  • [MeSH-major] Chondroblastoma / surgery. Skull Neoplasms / surgery. Temporal Bone

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  • (PMID = 18401591.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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40. Pans S, Brys R, Van Breuseghem I, Geusens E: Benign bone tumours of the spine. JBR-BTR; 2005 Jan-Feb;88(1):31-7
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  • [Title] Benign bone tumours of the spine.
  • A wide variety of primary bone tumours can involve the spine.
  • We present an overview of the primary benign bone tumours of the spine.
  • [MeSH-major] Magnetic Resonance Imaging. Spinal Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Humans. Spinal Diseases / diagnosis

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  • (PMID = 15792167.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 16
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41. Kossmann N, Gallachi G: [Local pain of the shoulder - osteoid osteoma]. Praxis (Bern 1994); 2010 Mar 17;99(6):359-5; quiz 366
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  • The cause was later identified in CT as being an osteoid osteoma, a benign bone tumour with high vascularity in the core (nidus) and a surrounding region of sclerosis.
  • These tumours usually develop before the age of thirty and the pain responds exquisitely to non-steroidal antirheumatic medication.
  • The tumour was finally removed (CT-guided drilling excision) whereupon the symptoms disappeared.
  • [MeSH-major] Bone Neoplasms / diagnosis. Image Processing, Computer-Assisted. Imaging, Three-Dimensional. Magnetic Resonance Imaging. Osteoma, Osteoid / diagnosis. Scapula / pathology. Shoulder Pain / etiology. Tomography, Spiral Computed
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Young Adult

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  • (PMID = 20235025.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 18
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42. Li J, Wang ZQ, Zhang YM, Song HP, Yuan L: [Application of allogeneic bone in surgical treatment of benign bone neoplasm]. Nan Fang Yi Ke Da Xue Xue Bao; 2006 Jul;26(7):987-90
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  • [Title] [Application of allogeneic bone in surgical treatment of benign bone neoplasm].
  • OBJECTIVE: To evaluate the clinical outcomes of allogeneic bone grafting for bone defect resulting from benign neoplasm resection and discuss the clinical application and bone defect repair mechanisms of allogeneic bone.
  • METHODS: A retrospective review was conducted of 135 patients with benign neoplasm resection who received bone defect filling with the allogeneic bone graft.
  • RESULTS: In the 104 patients with complete clinical follow-up data, 96 achieved bone union, 7 experienced relapses to require surgical intervention and 1 had severe infection to lead to failure of the operation.
  • The mean time for bone union was 9.7 months, and during the follow-up, no viral disease in relation to the graft was found after surgery.
  • CONCLUSION: Bone defect filling with allogeneic bone graft can be simple and safe in comparison with that with autograft or other biomaterials, and the bone healing time, infection rate and local tumor recurrence can be comparable with the autograft.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / methods

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  • (PMID = 16864094.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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43. Kitsoulis P, Mantellos G, Vlychou M: Osteoid osteoma. Acta Orthop Belg; 2006 Apr;72(2):119-25
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  • Osteoid osteoma is a relatively frequent benign bone tumour, consisting of osteoid and woven bone, and surrounded by a halo of reactive sclerotic bone, with an average size of the nidus less than 1.5 cm.
  • [MeSH-major] Bone Neoplasms. Osteoma, Osteoid

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  • (PMID = 16768252.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 42
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44. Ando A, Hatori M, Hosaka M, Hagiwara Y, Kita A, Itoi E: Eosinophilic granuloma arising from the pelvis in children: A report of three cases. Ups J Med Sci; 2008;113(2):209-16
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  • Eosinophilic granuloma (EG) is a benign tumor-like condition which is characterized by a clonal proliferation of Langerhans-type histiocytes and defined as a local form of Langerhans cell histiocytosis (LCH).
  • A status of EG in the bone is divided into acute and chronic phases.
  • Radiologically acute phase of EG is difficult to differentiate from a malignant bone tumor such as Ewing's sarcoma or acute osteomyelitis.
  • Chronic phase of EG may mimic a chronic osteomyelitis or a benign bone tumor.
  • These lesions resembled radiologically chronic osteomyelitis (Brodie's abscess) or a benign bone tumor and healed spontaneously after biopsy.
  • It was difficult to differentiate from a malignant tumor such as Ewing's sarcoma, or acute osteomyelitis.
  • Curettage of the affected site and bone grafting is usually accomplished.
  • [MeSH-major] Bone Neoplasms / complications. Eosinophilic Granuloma / etiology. Osteomyelitis / complications. Pelvis

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  • (PMID = 18509815.001).
  • [ISSN] 2000-1967
  • [Journal-full-title] Upsala journal of medical sciences
  • [ISO-abbreviation] Ups. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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45. Freschi S, Dodson NB: Osteoid osteoma: an uncommon cause of foot pain. J Am Podiatr Med Assoc; 2007 Sep-Oct;97(5):405-9
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  • An osteoid osteoma located in the forefoot can be difficult to diagnose, and the diagnosis is frequently delayed.
  • Although rarely seen in the metatarsal, osteoid osteoma should be included in the differential diagnosis of foot pain.
  • Findings from radiographs, magnetic resonance images, and a detailed clinical history led to the diagnosis of osteoid osteoma of the left second metatarsal.
  • We review osteoid osteoma, including the classic clinical presentation and treatment associated with this benign bone tumor.

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  • (PMID = 17901347.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Settakorn J, Lekawanvijit S, Arpornchayanon O, Rangdaeng S, Vanitanakom P, Kongkarnka S, Cheepsattayakorn R, Ya-In C, Thorner PS: Spectrum of bone tumors in Chiang Mai University Hospital, Thailand according to WHO classification 2002: A study of 1,001 cases. J Med Assoc Thai; 2006 Jun;89(6):780-7
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  • [Title] Spectrum of bone tumors in Chiang Mai University Hospital, Thailand according to WHO classification 2002: A study of 1,001 cases.
  • OBJECTIVE: The aim of the present study was to determine the spectrum, frequency and demographics of bone tumors.
  • MATERIAL AND METHOD: A retrospective study of the 1,001 bone tumor specimens from the files at the Pathology Department of the Chiang Mai University Hospital, Thailand from 2000 to 2004.
  • RESULTS: From the study, 41 were non-neoplastic mass lesions, and 960 were neoplastic, with 856 (89%) as primary and 104 (11%) as metastatic tumors.
  • In the primary tumor group, 654 (76%) cases were of hematologic origin, and 202 (24%) were non-hematologic.
  • The most common benign bone tumors were giant cell tumor (n = 37), osteochondroma (n = 25), and chondroma (n = 15).
  • The most common malignant bone tumors were lymphoma-leukemia (n = 583), metastatic malignancy (n = 104), plasma cell myeloma (n = 71), and osteosarcoma (n = 58).
  • CONCLUSION: The present study showed a higher frequency of osteosarcoma (68%), lower frequencies of chondrosarcoma (12%) and Ewing sarcoma (4%) among primary non-hematologic malignant bone tumors when compared with similar studies based on Western patients.
  • [MeSH-major] Bone Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Giant Cell Tumors / diagnosis. Giant Cell Tumors / epidemiology. Hospitals, University. Humans. Infant. Male. Middle Aged. Osteochondroma / diagnosis. Osteochondroma / epidemiology. Osteosarcoma / diagnosis. Osteosarcoma / epidemiology. Retrospective Studies. Thailand / epidemiology. World Health Organization

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  • (PMID = 16850677.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Thailand
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47. Harzallah L, Bouajina E, Rammeh N, Belhadj SK, Ghannouchi M, Kraiem C: [Iliac chondroma: a case report]. Tunis Med; 2005 Sep;83(9):578-80
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  • Chondroma is a benign bone tumour that usually occurs in the in carpal and phalangeal bones.
  • The diagnosis of chondroma was confirmed after surgical biopsy.
  • [MeSH-major] Bone Neoplasms / pathology. Chondroma / pathology. Ilium / pathology

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  • (PMID = 16383207.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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48. Fine HF, Ferrara DC, Ho IV, Takahashi B, Yannuzzi LA: Bilateral choroidal osteomas with polypoidal choroidal vasculopathy. Retin Cases Brief Rep; 2008;2(1):15-7
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  • BACKGROUND: A choroidal osteoma is a benign osseous tumor typically arising in the juxtapapillary or peripapillary area.
  • To our knowledge, this variant form of vasogenesis has not previously been described in association with this tumor.

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  • (PMID = 25389606.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Arantes M, Resende M, Honavar M, Pires MM, Pereira JR, Vaz AR: Benign osteoblastoma of the sphenoid bone. Skull Base; 2009 Nov;19(6):437-41
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  • [Title] Benign osteoblastoma of the sphenoid bone.
  • Osteoblastoma is an uncommon benign bone tumor that accounts for 1% of all primary bone tumors.
  • Well documented in the spine and long bones, it is rarely found in the skull, namely in the sphenoid bone, with only five cases reported in the literature.
  • We report a case of an 11-year-old girl with a histologically confirmed benign osteoblastoma in an unusual location and an atypical aspect on the imaging studies.

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  • [Cites] Cancer. 1956 Sep-Oct;9(5):1044-52 [13364889.001]
  • (PMID = 20436846.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2793891
  • [Keywords] NOTNLM ; Benign osteoblastoma / child / radical resection / sphenoid bone
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50. Wootton-Gorges SL: MR imaging of primary bone tumors and tumor-like conditions in children. Magn Reson Imaging Clin N Am; 2009 Aug;17(3):469-87, vi
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  • [Title] MR imaging of primary bone tumors and tumor-like conditions in children.
  • This article provides a review of the MR imaging features of the major primary malignant and benign bone tumors and tumorlike conditions encountered in the pediatric population.
  • Malignant tumors discussed include osteosarcoma, Ewing sarcoma, chondrosarcoma, lymphoma, and malignant fibrous histiocytoma.
  • Benign lesions discussed include simple bone cysts, aneurysmal bone cysts, giant cell tumor, osteochondroma, enchondroma, chondroblastoma, osteoid osteoma, osteoblastoma, nonossifying fibroma, fibrous dysplasia, osteofibrous dysplasia, hemangioma, and histiocytosis.
  • The use of MR imaging in the diagnosis of these lesions is discussed, and the text is enhanced with imaging examples of the lesions.
  • [MeSH-major] Bone Neoplasms / diagnosis. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adolescent. Bone Cysts / diagnosis. Bone Cysts / pathology. Cartilage Diseases / diagnosis. Cartilage Diseases / pathology. Child. Contrast Media. Humans

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  • (PMID = 19524197.001).
  • [ISSN] 1557-9786
  • [Journal-full-title] Magnetic resonance imaging clinics of North America
  • [ISO-abbreviation] Magn Reson Imaging Clin N Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 44
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51. Zegn W, Li G, Liu Z, Gao CH: [Bone morphogenetic protein compunds combined with autologous red bone marrow graft for treatment of benign bone tumors and tumor-like lesions in limbs]. Zhongguo Gu Shang; 2010 Oct;23(10):788-9
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  • [Title] [Bone morphogenetic protein compunds combined with autologous red bone marrow graft for treatment of benign bone tumors and tumor-like lesions in limbs].
  • [MeSH-major] Bone Marrow Transplantation / immunology. Bone Morphogenetic Proteins / therapeutic use. Bone Neoplasms / therapy. Combined Modality Therapy. Transplantation, Autologous / immunology

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  • (PMID = 21137298.001).
  • [ISSN] 1003-0034
  • [Journal-full-title] Zhongguo gu shang = China journal of orthopaedics and traumatology
  • [ISO-abbreviation] Zhongguo Gu Shang
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Bone Morphogenetic Proteins
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52. Faik A, Mahfoud Filali S, Lazrak N, El Hassani S, Hajjaj-Hassouni N: Spinal cord compression due to vertebral osteochondroma: report of two cases. Joint Bone Spine; 2005 Mar;72(2):177-9
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  • Osteochondroma, or exostosis, is the most common of all benign bone tumors.

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  • (PMID = 15797501.001).
  • [ISSN] 1297-319X
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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53. Xu J, Xu CR, Wu H, Pan HL, Tian J: Osteochondroma in the lumbar intraspinal canal causing nerve root compression. Orthopedics; 2009 Feb;32(2):133
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  • Osteochondromas, which are benign bone tumors that usually develop on long bones, tubular bones, are rarely found in the spine.
  • Considering differential diagnosis, lumbar facet synovial cysts must be excluded as they can also cause myeloradiculopathy with the similar mechanism.
  • The tumor, approximately 6x7x11 mm, was identified after laminectomy of the L5 laminae.
  • Postoperative histopathologic examination confirmed our hypothesis of benign osteochondroma.
  • Computed tomography and MRI are helpful for the preoperatively precise indication of tumor extent and its relationships with the adjacent.

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  • (PMID = 19301786.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Kim J, Kumar R, Raymond AK, Ayala AG: Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature. Skeletal Radiol; 2010 Jun;39(6):583-7
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  • [Title] Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature.
  • Chondroblastoma is a benign bone tumor that typically arises in the epiphysis of a long bone.
  • We describe such a case of chondroblastoma arising in the iliac bone.
  • The radiographs and CT revealed an expansile lytic lesion in the right iliac bone.
  • The histopathology revealed the lesion to be a chondroblastoma with secondary features of aneurysmal bone cyst.
  • An en bloc surgical resection of the tumor was performed.
  • [MeSH-major] Bone Cysts, Aneurysmal / complications. Bone Cysts, Aneurysmal / diagnostic imaging. Bone Neoplasms / complications. Bone Neoplasms / diagnostic imaging. Chondroblastoma / complications. Chondroblastoma / diagnostic imaging. Ilium / diagnostic imaging. Tomography, X-Ray Computed

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  • [Cites] Skeletal Radiol. 2006 Jan;35(1):49-52 [16010594.001]
  • [Cites] Clin Orthop Relat Res. 1973 Sep;(95):300-12 [4585180.001]
  • [Cites] Skeletal Radiol. 2006 May;35(5):295-7 [16501973.001]
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  • [Cites] Br J Radiol. 1986 Mar;59(699):197-204 [3456251.001]
  • (PMID = 19936740.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 12
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55. Niethard M, Rogalski M, Deja M, Zacher J: [Partial physeal growth arrest with increasing genu varum deformity caused by a cortical enchondroma--a case report]. Z Orthop Unfall; 2008 Nov-Dec;146(6):725-9
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  • The X-ray and MRI investigations have shown a benign lesion like osteofibroma of the mediodistal femur with an affection of the medial physis.
  • 1) resection of the benign lesion and arthroscopically assisted resection of the bony bar with fat-patch interposition;.
  • CONCLUSION: In cases of rare partial bridging of the physis induced by a benign bone tumour one can achieve early correction of axial deviation during growth with resection, interposition of a fat patch and temporary hemiepiphyseodesis.
  • [MeSH-major] Arthroscopy. Bone Malalignment / surgery. Bone Plates. Cartilage, Articular / surgery. Chondroma / surgery. Femur / surgery. Growth Plate / surgery. Knee Joint / surgery

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  • (PMID = 19085720.001).
  • [ISSN] 1864-6697
  • [Journal-full-title] Zeitschrift für Orthopädie und Unfallchirurgie
  • [ISO-abbreviation] Z Orthop Unfall
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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56. Figl M, Leixnering M: Retrospective review of outcome after surgical treatment of enchondromas in the hand. Arch Orthop Trauma Surg; 2009 Jun;129(6):729-34
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  • BACKGROUND: Tumours of the skeleton of the hand are rare.
  • While the majority of bone tumours are benign (89.4%), a small number show signs of malignancy (4.4%).
  • Among the benign bone tumours of the skeleton of the hand, enchondromas are the most common, at 35-65%.
  • The most common site of an enchondroma was the proximal phalanx in 17 cases, followed by the metacarpal bone in 8 cases and the middle phalanx in 5 cases.
  • For accurate diagnosis, conventional X-ray examination and if necessary, a contrast medium MRI should be performed.
  • Depending on its spread, the defect in the extirpation cavity should be filled with autogenous spongy bone.
  • [MeSH-major] Bone Neoplasms / surgery. Chondroma / surgery. Hand / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Transplantation. Female. Fingers / pathology. Fingers / surgery. Fractures, Spontaneous / diagnosis. Fractures, Spontaneous / pathology. Fractures, Spontaneous / surgery. Hand Injuries / diagnosis. Hand Injuries / pathology. Hand Injuries / surgery. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 18726106.001).
  • [ISSN] 1434-3916
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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57. Cai Y, Mohseny AB, Karperien M, Hogendoorn PC, Zhou G, Cleton-Jansen AM: Inactive Wnt/beta-catenin pathway in conventional high-grade osteosarcoma. J Pathol; 2010 Jan;220(1):24-33
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  • Osteosarcoma is the most common malignant bone tumour, with a peak incidence in children and young adolescents, suggesting a role of rapid bone growth in its pathogenesis.
  • Therefore, in this study, we examined nuclear beta-catenin expression in 52 human osteosarcoma biopsies, 15 osteoblastomas (benign bone tumours), and four human osteosarcoma cell lines by immunohistochemistry.
  • Stimulation of the Wnt/beta-catenin pathway by GIN significantly reduced cell proliferation in the cell lines MG-63 and U-2-OS and enhanced differentiation in the cell lines HOS and SJSA-1, as shown by an increase in alkaline phosphatase (ALP) activity and mineralization.
  • [MeSH-major] Bone Neoplasms / physiopathology. Osteosarcoma / physiopathology. Wnt Proteins / physiology. beta Catenin / metabolism
  • [MeSH-minor] Animals. Cell Differentiation / physiology. Cell Proliferation. Glycogen Synthase Kinase 3 / antagonists & inhibitors. Glycogen Synthase Kinase 3 / physiology. Hedgehog Proteins / physiology. Humans. Intercellular Signaling Peptides and Proteins / metabolism. Mice. Neoplasm Proteins / metabolism. Neoplasm Proteins / physiology. Osteoblasts / pathology. Recombinant Proteins / pharmacology. Reverse Transcriptase Polymerase Chain Reaction / methods. Signal Transduction / drug effects. Signal Transduction / physiology. Tumor Cells, Cultured. Wnt3 Protein

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  • [CommentIn] J Pathol. 2010 Jan;220(1):1-4 [19890890.001]
  • (PMID = 19882675.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DKK1 protein, human; 0 / Hedgehog Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Neoplasm Proteins; 0 / Recombinant Proteins; 0 / Wnt Proteins; 0 / Wnt3 Protein; 0 / beta Catenin; EC 2.7.11.1 / glycogen synthase kinase 3 beta; EC 2.7.11.26 / Glycogen Synthase Kinase 3
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58. Rodríguez Paramás A, Lendoiro Otero C, González García JA, Souviron Encabo R, Scola Yurrita B: [Temporal bone chondroblastoma. A clinical case and literature review]. Acta Otorrinolaringol Esp; 2006 Aug-Sep;57(7):336-8
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  • [Title] [Temporal bone chondroblastoma. A clinical case and literature review].
  • [Transliterated title] Condroblastoma de hueso temporal. Caso clínico y revisión de la literatura.
  • After radiologic diagnosis, intraoperatory biopsy and surgical removal, the anatomopathological result confirmed the histology of chondroblatoma, with a satisfactory postoperative evolution.
  • The chondroblastoma is a benign bone tumor typically located in the epiphysis of long bones and the temporal bone is an excepcional location as we have verified through a literature review.
  • [MeSH-major] Chondroblastoma. Skull Neoplasms. Temporal Bone

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  • (PMID = 17036998.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 9
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59. Ramboaniaina S, Hoang DV, Berger M: [Aneurysmal carpal scaphoid cyst. A case report]. Chir Main; 2009 Feb;28(1):46-9
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  • Aneurysmal bone cyst is a rare, benign bone tumor and its location in the carpal scaphoid has never been described in the literature.
  • [MeSH-major] Bone Cysts, Aneurysmal / diagnosis. Scaphoid Bone / radiography

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  • (PMID = 19095484.001).
  • [ISSN] 1297-3203
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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60. Schnirring-Judge M, Visser J: Resection and reconstruction of an osteochondroma of the hallux: a review of benign bone tumors and a description of an unusual case. J Foot Ankle Surg; 2009 Jul-Aug;48(4):495-505
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  • [Title] Resection and reconstruction of an osteochondroma of the hallux: a review of benign bone tumors and a description of an unusual case.
  • Osteochondroma, which is also known as exostosis, is the most common benign bone tumor.
  • In this review, we describe the clinical and diagnostic imaging characteristics of benign bone tumors and, in particular, the osteochondroma and its surgical management.
  • [MeSH-major] Bone Neoplasms / surgery. Hallux / surgery. Osteochondroma / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Neoplasms, Post-Traumatic / pathology. Young Adult

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  • (PMID = 19577730.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 36
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61. Aldea S, Bonneville F, Poirier J, Chiras J, George B, Carpentier A: Acute spinal cord compression in hereditary multiple exostoses. Acta Neurochir (Wien); 2006 Feb;148(2):195-8; discussion 198
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  • Osteocartilaginous exostoses are benign bone tumors frequently found in the metaphysis of long bones but rarely in the spine.


62. Matysiakiewicz J, Tomasik P, Miszczyk L, Spindel J, Widuchowski J, Koczy B, Chrobok A, Mrozek T: Manifestations, diagnosis and surgical treatment of enchondroma--own experience. Ortop Traumatol Rehabil; 2010 Mar-Apr;12(2):155-9
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  • [Title] Manifestations, diagnosis and surgical treatment of enchondroma--own experience.
  • BACKGROUND: An enchondroma is a rather common benign tumour of bone that originates from cartilage.The course is usually benign but they have a tendency to recur and are sometimes invasive, especially when developing in long bones.
  • RESULTS: The tumours were mostly located in phalanges of the fingers--55 cases (37%), and metacarpal bones--21 cases (14%).
  • A total of 170 surgical procedures were performed, mostly (120 procedures) tumour resections with bone graft implantation.
  • CONCLUSION: Total resection of the enchondroma combined with spongy bone grafting is the main treatment of chondroma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Chondroma / diagnosis. Chondroma / surgery

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  • (PMID = 20453254.001).
  • [ISSN] 1509-3492
  • [Journal-full-title] Ortopedia, traumatologia, rehabilitacja
  • [ISO-abbreviation] Ortop Traumatol Rehabil
  • [Language] eng; pol
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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63. Katthagen BD, Prub A: [Bone allografting]. Orthopade; 2008 Aug;37(8):764-71
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  • [Title] [Bone allografting].
  • [Transliterated title] Transplantation allogenen Knochens.
  • Bone allografts facilitate bone reconstruction in orthopedic surgery.
  • After implantation, bone allografts become necrotic but are incorporated and remodeled in the recipient bone with good regenerative capacity.
  • We use bone allografts in about 3% of all elective orthopedic operations in our hospital.
  • We use bone allografts regularly in acetabuloplasty in cases of severe residual hip dysplasia.
  • Bone allografts are most often used in revision total joint arthroplasty.
  • In cases of reconstruction of defects in benign bone tumors and tumor-like lesions, bone allografts are often suitable.
  • In fibrous dysplasia, corticocancellous bone allografts are even the treatment of choice.
  • [MeSH-major] Bone Transplantation / methods. Orthopedic Procedures
  • [MeSH-minor] Acetabulum / surgery. Adult. Arthroplasty, Replacement. Bone Banks. Bone Neoplasms / surgery. Bone Regeneration. Bone Remodeling / physiology. Child. Disinfection. Follow-Up Studies. Hip Dislocation, Congenital / surgery. Humans. Prosthesis Failure. Reoperation. Transplantation, Homologous

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  • [Cites] Clin Orthop Relat Res. 1968 Nov-Dec;61:61-78 [4236465.001]
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  • (PMID = 18584151.001).
  • [ISSN] 0085-4530
  • [Journal-full-title] Der Orthopade
  • [ISO-abbreviation] Orthopade
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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64. Abou-Elhamd KE: Frontal sinus cementifying ossifying fibroma. Saudi Med J; 2005 Mar;26(3):470-2
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  • Cementifying ossifying fibroma is a fibro-osseous lesion which produces cementum.
  • Cementifying ossifying fibroma is a mesodermal, non-odontogenic tumor of ectopic multipotential periodontal membrane blast cells.
  • Although, it is a benign bone tumor, it has an aggressive destructive behavior in patients under 20 years of age with high tendency for recurrence.
  • [MeSH-major] Bone Neoplasms / diagnosis. Fibroma, Ossifying / diagnosis. Frontal Sinus

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  • (PMID = 15806222.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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65. Gebert C, Brinkschmidt C, Bielack S, Bernhardt T, Jürgens H, Böcker W, Winkelmann W, Bürger H, Gosheger G: The potential of comparative genomic hybridization as a tool in the differential diagnosis of matrix-producing bone lesions. Int J Surg Pathol; 2006 Jul;14(3):187-92
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  • [Title] The potential of comparative genomic hybridization as a tool in the differential diagnosis of matrix-producing bone lesions.
  • Matrix-producing bone lesions consist of a wide variety of benign and malignant conditions.
  • With respect to morphology, an overlap exists between benign and malignant bone tumors that causes difficulties in the final determination of the tumor.
  • This study was conducted to show the potential of comparative genomic hybridization as a tool in the differential diagnosis of matrix-producing bone lesions.
  • Thirty benign bone tumors were evaluated by conventional comparative genomic hybridization.
  • In contrast benign tumors or tumor-like lesions did not reveal any chromosomal alterations.
  • Comparative genomic hybridization is a useful adjunct in the complicated differential diagnostic algorithms of matrix-producing bone tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chromosome Aberrations. DNA, Neoplasm / genetics. Molecular Diagnostic Techniques / methods. Osteosarcoma / diagnosis

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  • (PMID = 16959697.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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66. Fraquet N, Faizon G, Rosset P, Phillipeau J-, Waast D, Gouin F: Long bones giant cells tumors: treatment by curretage and cavity filling cementation. Orthop Traumatol Surg Res; 2009 Oct;95(6):402-6
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  • [Title] Long bones giant cells tumors: treatment by curretage and cavity filling cementation.
  • OBJECTIVE: Giant cell tumors (GCT) of bone are benign tumors with local aggressiveness that most of the time occur around the metaphyseal area of long bones, often in contact with the articular cartilage.
  • Twenty-six of these tumors were present around the knee: 14 at the distal femur and 12 at the proximal tibia.
  • Preoperative radiological evaluation with standard X-rays showed that the tumor measured a mean 71x45mm, for a mean volume of 78cm(3).
  • Two cases of minor osteoarthritis progression were noted (one less than 50% and a simple densification of subchondral bone), requiring no specific treatment.
  • Diagnosis of recurrence can be made earlier because of the thin scalable border at the bone-cement interface.
  • [MeSH-major] Bone Cements / therapeutic use. Bone Neoplasms / surgery. Femur / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Tibia / surgery

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  • [Copyright] 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 19767256.001).
  • [ISSN] 1877-0568
  • [Journal-full-title] Orthopaedics & traumatology, surgery & research : OTSR
  • [ISO-abbreviation] Orthop Traumatol Surg Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Bone Cements
  • [General-notes] NLM/ Original DateCompleted: 20100201
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67. Kim WJ, Kim KJ, Lee SK, Choy WS: Solitary pelvic osteochondroma causing L5 nerve root compression. Orthopedics; 2009 Dec;32(12):922
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  • Osteochondroma is the most common benign bone tumor, accounting for more than one-third of all benign bone tumors.
  • Thus, surgical excision is not routinely recommended unless the tumor causes clinical symptoms or cosmetic distress.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / surgery. Decompression, Surgical / methods. Osteochondroma / complications. Osteochondroma / surgery. Pelvic Bones / radiography. Pelvic Bones / surgery. Radiculopathy / etiology. Radiculopathy / surgery

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  • [Copyright] Copyright 2009, SLACK Incorporated.
  • (PMID = 19968229.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Ozyurek S, Rodop O, Kose O, Cilli F, Mahirogullari M: Aneurysmal bone cyst of the fifth metacarpal. Orthopedics; 2009 Aug;32(8)
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  • [Title] Aneurysmal bone cyst of the fifth metacarpal.
  • Aneurysmal bone cyst is a rare, rapidly growing, and destructive benign bone tumor that even more rarely involves the bones of the hand.
  • Various treatment options for aneurysmal bone cyst have been reported in the literature, but controversy exists regarding optimal treatment.
  • Physical and radiographic examination of the hand was consistent with aneurysmal bone cyst.
  • After biopsy, pathologic examination confirmed the diagnosis of aneurysmal bone cyst.
  • En-block resection of the tumor and autologous bicortical strut graft fixation with Kirschner wires was performed.
  • Radiographic examination demonstrated the osseous integration of the graft with no signs of recurrence.
  • [MeSH-major] Bone Cysts, Aneurysmal / radiography. Bone Cysts, Aneurysmal / surgery. Bone Transplantation. Metacarpal Bones / radiography. Metacarpal Bones / surgery. Osteotomy

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  • (PMID = 19708623.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Gibbs CP, Lewis VO, Peabody T: Beyond bone grafting: techniques in the surgical management of benign bone tumors. Instr Course Lect; 2005;54:497-503
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  • [Title] Beyond bone grafting: techniques in the surgical management of benign bone tumors.
  • The traditional surgical treatment of benign bone tumors has been curettage and autologous bone graft or marginal resection of expendable bones.
  • Recently, however, surgeons have been evaluating the results of treatments using limited surgical approaches, including percutaneous treatments, alternatives to autograft bone, and thermal or cytotoxic adjuvant therapies.
  • This process has been facilitated by the availability of multiple bone grafting materials and substitutes, the use of cross-sectional imaging, and technology such as that used with radiofrequency ablation.
  • Techniques using these therapies in two benign bone tumor models are described.
  • The use of percutaneous radiofrequency ablation, now used for both benign and malignant disease, is reviewed as a surgical alternative for osteoid osteoma.
  • The role of adjuvant therapies such as liquid nitrogen and phenol, as well as the indications for resection, are described in the management of giant cell tumors of bone.
  • [MeSH-major] Bone Neoplasms / surgery. Catheter Ablation / methods. Giant Cell Tumor of Bone / surgery. Osteoma, Osteoid / surgery. Reconstructive Surgical Procedures / methods
  • [MeSH-minor] Bone Transplantation / methods. Humans. Prosthesis Implantation / methods

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  • (PMID = 15948474.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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70. Tsuchiya H, Morsy AF, Matsubara H, Watanabe K, Abdel-Wanis ME, Tomita K: Treatment of benign bone tumours using external fixation. J Bone Joint Surg Br; 2007 Aug;89(8):1077-83
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  • [Title] Treatment of benign bone tumours using external fixation.
  • We present a retrospective study of patients suffering from a variety of benign tumours in whom external fixators were used to treat deformity and limb-length discrepancy, and for the reconstruction of bone defects.
  • The diagnosis was Ollier's disease in 12 limbs, fibrous dysplasia in 11, osteochondroma in eight, giant cell tumour in five, osteofibrous dysplasia in five and non-ossifying fibroma in two.
  • [MeSH-major] Bone Neoplasms / surgery. External Fixators. Fracture Fixation / methods. Neoplasms, Connective Tissue / surgery. Osteochondrodysplasias / surgery. Osteochondroma / surgery

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  • (PMID = 17785749.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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71. Reize F, Buess E: Humeral osteochondroma causing a subscapularis tear: a rare source of shoulder dysfunction. Arch Orthop Trauma Surg; 2007 Jan;127(1):67-70
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  • The proximal humerus is a well-known site of predilection for the solitary osteochondroma-the most common benign bone tumor.
  • The patient was successfully treated by open resection of the tumor and reattachment of the tendon with suture anchors.
  • [MeSH-major] Bone Neoplasms / complications. Humerus. Osteochondroma / complications. Rotator Cuff / injuries

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  • (PMID = 16927096.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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72. Goessmann H, Zorger N, Schreyer AG: [Aneurysmic bone cyst of the head of the mandible: a rare site of a benign bone tumor]. Rofo; 2009 Sep;181(9):902-4
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  • [Title] [Aneurysmic bone cyst of the head of the mandible: a rare site of a benign bone tumor].
  • [Transliterated title] Aneurysmatische Knochenzyste des Mandibulaköpfchens: eine seltene Lokalisation des benignen Knochentumors.
  • [MeSH-major] Bone Cysts, Aneurysmal / diagnosis. Magnetic Resonance Imaging. Mandibular Diseases / diagnosis. Sternoclavicular Joint. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Biopsy. Bone Plates. Curettage. Diagnosis, Differential. Female. Humans. Mandibular Condyle / pathology. Mandibular Condyle / surgery. Recurrence. Reoperation

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  • (PMID = 19582659.001).
  • [ISSN] 1438-9010
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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73. Montañez-Heredia E, Serrano-Montilla J, Merino-Ruiz ML, Amores-Ramírez F, Villalobos-Martín J: Osteoid osteoma: CT-guided radiofrequency ablation. Acta Orthop Belg; 2009 Feb;75(1):75-80
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  • Osteoid osteoma is a benign bone tumour; its main symptom is pain, which is sometimes resistant to analgesic or anti-inflammatory medication.
  • [MeSH-major] Bone Neoplasms / surgery. Osteoma, Osteoid / surgery

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  • (PMID = 19358403.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Belgium
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74. Wicart P, Seringe R: [Protective limp]. Arch Pediatr; 2008 Mar;15(3):340-8
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  • The diagnosis of acute transient synovitis (irritable hip) should only be made after excluding other conditions including benign bone tumours (such as ostioid osteoma), malignant tumours, inflammatory monoarthritis, primary osteochondritis of the hip, trauma with or without fracture, apophysitis, leukemia, etc.
  • The diagnosis of acute transient synovitis should be questioned if the condition persists for more than seven days.
  • After the age of nine years, the diagnosis that is important not to miss is proximal femoral epiphysiolysis, because this condition can have serious implications for the future function of the hip.
  • Finally, a psychogenic aetiology, tendinitis, or sprain should not be considered in children, and they risk delaying the diagnosis of a potentially serious condition.

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  • (PMID = 18314314.001).
  • [ISSN] 0929-693X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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75. van de Luijtgaarden AC, Veth RP, Slootweg PJ, Wijers-Koster PM, Schultze Kool LJ, Bovee JV, van der Graaf WT: Metastatic potential of an aneurysmal bone cyst. Virchows Arch; 2009 Nov;455(5):455-9
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  • [Title] Metastatic potential of an aneurysmal bone cyst.
  • Aneurysmal bone cysts (ABCs) are benign bone tumors consisting of blood-filled cavities lined by connective tissue septa.
  • Diagnosis was confirmed by the presence of a break in the USP6 gene, which is pathognomonic for ABC, in a pulmonary metastasis of our patient.
  • Sarcomatous transformation as an explanation for this behavior was ruled out by demonstrating diploid DNA content in both the pulmonary lesion and the primary tumor.
  • [MeSH-major] Bone Cysts, Aneurysmal / pathology. Bone Neoplasms / pathology. Neoplasms, Second Primary / pathology. Osteosarcoma / pathology. Proto-Oncogene Proteins / genetics. Ubiquitin Thiolesterase / genetics

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  • (PMID = 19838726.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; 0 / Proto-Oncogene Proteins; 2S9ZZM9Q9V / Bevacizumab; EC 3.1.2.15 / USP6 protein, human; EC 3.1.2.15 / Ubiquitin Thiolesterase
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76. Ben hadj Hamida F, Jlaiel R, Ben Rayana N, Mahjoub H, Mellouli T, Ghorbel M, Krifa F: [Craniofacial fibrous dysplasia: a case report]. J Fr Ophtalmol; 2005 Oct;28(8):e6
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  • Fibrous dysplasia is classified among benign bone tumors.
  • It is a bone development anomaly characterized by hamartoma proliferation of fibrous tissue within the medullary bone, with secondary bony metaplasia, producing immature, newly formed and weakly calcified bone, without maturation of the osteoblast.
  • Its diagnosis is not always straightforward because the functional symptomology is often absent or not specific.
  • Medical imagery is necessary and in difficult cases a bone biopsy.
  • [MeSH-major] Facial Bones. Fibrous Dysplasia, Polyostotic / diagnosis. Skull

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  • (PMID = 16249758.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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77. Finstein JL, Hosalkar HS, Ogilvie CM, Lackman RD: Case reports: an unusual complication of radiofrequency ablation treatment of osteoid osteoma. Clin Orthop Relat Res; 2006 Jul;448:248-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoid osteoma is a benign bone tumor traditionally treated nonoperatively or by operative excision.
  • [MeSH-major] Bone Neoplasms / surgery. Catheter Ablation / adverse effects. Osteoma, Osteoid / surgery. Skin / pathology. Skin Diseases / etiology. Tibia

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  • [CommentIn] Clin Orthop Relat Res. 2006 Oct;451:290-1; author reply 291-2 [16906101.001]
  • [CommentIn] Clin Orthop Relat Res. 2007 Jul;460:285; author reply 285-6 [17534193.001]
  • (PMID = 16826123.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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78. Heck RK, Pope WD, Ahn JI, Smith RA, Webber BL: Histologic evaluation of the depth of necrosis produced by argon beam coagulation: implications for use as adjuvant treatment of bone tumors. J Surg Orthop Adv; 2009;18(2):69-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histologic evaluation of the depth of necrosis produced by argon beam coagulation: implications for use as adjuvant treatment of bone tumors.
  • Argon beam coagulation (ABC) has been advocated as adjuvant treatment after curettage of aggressive benign bone tumors.
  • This study was done to evaluate the depth of necrosis in cancellous bone treated with ABC.
  • A 6-month-old pig was sacrificed and 20 1.5-cm cortical windows were created in the metaphyseal areas of the humeri, femora, and tibiae, exposing the underlying cancellous bone.
  • [MeSH-major] Bone Neoplasms / surgery. Bone and Bones / pathology. Laser Coagulation / instrumentation. Lasers, Excimer / therapeutic use

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  • (PMID = 19602333.001).
  • [ISSN] 1548-825X
  • [Journal-full-title] Journal of surgical orthopaedic advances
  • [ISO-abbreviation] J Surg Orthop Adv
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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79. Edwards PC, Fantasia JE, Saini T, Rosenberg TJ, Sachs SA, Ruggiero S: Clinically aggressive central giant cell granulomas in two patients with neurofibromatosis 1. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Dec;102(6):765-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Neurofibromatosis 1 (NF1) is an autosomal dominantly inherited disorder caused by a spectrum of mutations affecting the Nf1 gene.
  • Affected patients develop benign and malignant tumors at an increased frequency.
  • Clinical findings include multiple cutaneous café-au-lait pigmentations, neurofibromas, axillary freckling, optic gliomas, benign iris hamartomas (Lisch nodules), scoliosis, and poorly defined soft tissue lesions of the skeleton.
  • While the presence of CGCGs of the jaws in patients with NF1 could represent either a coincidental association or a true genetic linkage, we propose that this phenomenon is most likely related to NF1-mediated osseous dysplasia.
  • Compared to normal bone, the Nf1-haploinsufficient bone in a patient with NF1 may be less able to remodel in response to as of yet unidentified stimuli (e.g. excessive mechanical stress and/or vascular fragility), and consequently may be more susceptible to developing CGCG-like lesions.
  • Alternatively, the CGCG in NF1 patients could represent a true neoplasm, resulting from additional, as of yet unidentified, genetic alterations to Nf1-haploinsufficient bone.


80. Adams SC, Potter BK, Robinson PG, Temple HT: Giant cell tumor of the distal femur associated with complete tumor necrosis. Orthopedics; 2010 Sep;33(9):688
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  • [Title] Giant cell tumor of the distal femur associated with complete tumor necrosis.
  • Giant cell tumor is a benign tumor of bone with a predilection for juxta-articular locations.
  • Although not malignant, giant cell tumor often exhibits unpredictable and locally aggressive behavior, and in rare cases can metastasize in the absence of histologic malignancy.
  • Partial tumor necrosis has been infrequently reported within typical giant cell tumor.
  • A 17-year-old girl presented with a right distal femur giant cell tumor associated with complete tumor necrosis on histopathologic analysis.
  • The etiology, prevalence, and implications of complete necrosis in previously untreated giant cell tumor of bone remain unclear, as there are no previously published reports.
  • There were no radiographic signs of the necrotic tumor space remodeling with new bone.
  • The patient was treated with standard extended intralesional curetting through a generous cortical window permitting visualization of the entire lesion, and systematic high speed burring and thermal electrocautery ablation of the periphery, followed by micro particulate allogenic bone grafting.
  • At short-term follow-up, she had healed well with no evidence of tumor recurrence.
  • This article presents the first case, to our knowledge, of complete spontaneous tumor necrosis in a previously untreated bone giant cell tumor.
  • Increased understanding of spontaneous tumor necrosis associated with giant cell tumor may help guided future targeted medical and surgical treatment modalities.
  • [MeSH-major] Femoral Neoplasms / pathology. Giant Cell Tumor of Bone / pathology

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20839701.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Al-Balas H, Omari H, Mustafa Z, Matalka I: Osteoid osteoma of the odontoid process of the axis associated with atlanto-axial fusion. Br J Radiol; 2009 Jul;82(979):e126-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoid osteoma is a primary benign bone tumour with characteristic imaging and pathological features.
  • The case was diagnosed pre-operatively using plain radiography, multiplanar helical CT, contrast-enhanced MRI and radioisotope bone scanning.
  • [MeSH-major] Atlanto-Axial Joint / abnormalities. Odontoid Process. Osteoma, Osteoid / diagnosis. Spinal Neoplasms / diagnosis

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  • (PMID = 19541938.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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82. Tsai WC, Liao CJ, Wu CT, Liu CY, Lin SC, Young TH, Wu SS, Liu HC: Clinical result of sintered bovine hydroxyapatite bone substitute: analysis of the interface reaction between tissue and bone substitute. J Orthop Sci; 2010 Mar;15(2):223-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical result of sintered bovine hydroxyapatite bone substitute: analysis of the interface reaction between tissue and bone substitute.
  • BACKGROUND: Autogenic bone graft is the first choice for managing bone defects.
  • However, donor site-associated morbidity and limited bone volume are constraints in clinical applications.
  • Allografts can provide sufficient amounts for bone defects but have a high risk of infection.
  • Bone substitute composed of hydroxyapatite (HA) is an alternative material for avoiding the aforementioned risks.
  • Sintered bovine bone is a naturally occurring HA that has been proved to have excellent bioactivity for inducing osteoblastic expression and new bone formation in animal studies.
  • The objective of this study was to evaluate the interactions between the tissue and the bone substitute composed of HA (sintered from bovine bone) in the human body.
  • METHODS: From 2003 to 2005, a total of 33 patients were enrolled to receive the sintered bovine HA as a bone substitute.
  • Inclusion criteria were fractures with bony defects, benign bone tumors with a cavity, and spinal fusions.
  • Bone healing was monitored by a series of radiographs, and bone microstructure was checked by scanning electron microscopy (SEM) and von Kossa staining.
  • New bone formation on the surface of the sintered bovine HA was seen under microscopic observation.
  • Tight bonding between the interface of the bone and the sintered bovine HA was shown with SEM/energy-dispersive spectroscopy and von Kossa staining.
  • CONCLUSIONS: Sintered bovine HA is a suitable material as a bone substitute to provide bone growth and promote bone healing.
  • [MeSH-major] Biocompatible Materials / therapeutic use. Bone Substitutes. Durapatite / therapeutic use. Fractures, Bone / surgery. Spinal Fusion / methods

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  • (PMID = 20358336.001).
  • [ISSN] 1436-2023
  • [Journal-full-title] Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
  • [ISO-abbreviation] J Orthop Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Bone Substitutes; 91D9GV0Z28 / Durapatite
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83. Ozalp T, Yercan H, Okçu G, Ozdemir O, Coskunol E, Bégué T, Calli I: [Giant-cell tumor of the hand: midterm results in five patients]. Rev Chir Orthop Reparatrice Appar Mot; 2007 Dec;93(8):842-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant-cell tumor of the hand: midterm results in five patients].
  • [Transliterated title] Tumeur à cellules géantes de la main: résultats du traitement: 5 cas au recul moyen de 7, 8 ans.
  • PURPOSE OF THE STUDY: Giant-cell bone tumors are benign but have great potential for recurrence.
  • Frequently observed in epiphyseal areas of tubular bones, these tumors are rarely found in hand localizations.
  • We examined the characteristic features of giant-cell tumors of the hand and analyzed the pertinence of surgical treatment.
  • We noted complications, consequences of recurrence and later operations on the same tumor site in five cases.
  • CASE REPORTS: Five patients treated between 1973 and 2000 for giant-cell tumors involving the hand bones were reviewed retrospectively.
  • The surgical procedure was curettage for two, curettage with bone graft for two and amputation for one.
  • At 7.8 years follow-up recurrence was noted for four of the five tumors.
  • In all six episodes of recurrent tumor were treated.
  • DISCUSSION: Treatment of giant-cell tumors involving the hand bones is designed to eradicate the tumor and also protect hand function while keeping in mind the aggressive nature of these benign tumors.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumors / surgery. Hand Bones / surgery
  • [MeSH-minor] Adult. Aged. Amputation. Bone Transplantation. Curettage. Female. Finger Phalanges / surgery. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Soft Tissue Neoplasms / surgery. Thumb / surgery. Time Factors. Treatment Outcome

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  • (PMID = 18166957.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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84. Ozturk C, Tezer M, Hamzaoglu A: Solitary osteochondroma of the cervical spine causing spinal cord compression. Acta Orthop Belg; 2007 Feb;73(1):133-6
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  • Osteochondromas are common benign tumours of bone that often occur in the metaphysodiaphyseal parts of long bones.
  • Radiographs, CT and MRI showed a solitary benign appearing expansile bone tumour arising from the left vertebral lamina of C-1, spreading to C-2, exerting an eccentric posterolateral compression on the spinal cord in the left part of the spinal canal and causing stenosis of the left neural foramen between C-1 and C-2.
  • [MeSH-minor] Bone Screws. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neck Pain / etiology. Orthopedic Fixation Devices. Spinal Fusion. Spinal Stenosis / etiology. Tomography, X-Ray Computed

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  • (PMID = 17441673.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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85. Akhlaghpoor S, Aziz Ahari A, Ahmadi SA, Arjmand Shabestari A, Gohari Moghaddam K, Alinaghizadeh MR: Histological evaluation of drill fragments obtained during osteoid osteoma radiofrequency ablation. Skeletal Radiol; 2010 May;39(5):451-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Osteoid osteoma (OO) is a benign bone tumor diagnosed mainly on the basis of the patient's history and radiological data.
  • The aim of this study was to assess the diagnostic value of a histological evaluation of the bone fragments obtained during radiofrequency ablation (RFA).
  • Bone fragments collected from the drill were examined by two experienced pathologists, independently.
  • In 27 cases (69.2%) this diagnosis was confirmed pathologically.
  • CONCLUSION: Histological confirmation of OO based on drill fragments is similarly frequent as previously reported for standard bone biopsy.
  • [MeSH-major] Biopsy / methods. Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Bone and Bones / pathology. Catheter Ablation / methods. Osteoma, Osteoid / diagnosis. Osteoma, Osteoid / surgery

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  • (PMID = 20204353.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Germany
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86. Futani H, Fukunaga S, Nishio S, Yagi M, Yoshiya S: Successful treatment of bilateral calcaneal intraosseous lipomas using endoscopically assisted tumor resection. Anticancer Res; 2007 Nov-Dec;27(6C):4311-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful treatment of bilateral calcaneal intraosseous lipomas using endoscopically assisted tumor resection.
  • BACKGROUND: Intraosseous lipoma is a rare benign bone tumor.
  • Curettage was performed through small bone fenestrations in the medial and lateral aspects under observation with a 2.7-mm-diameter Hopkins telescope.
  • The bone void was filled with beta-tricalcium phosphate (beta-TCP).
  • CONCLUSION: Endoscopically assisted curettage is feasible in patients with benign bone tumors of the calcanei to avoid a long period of non-weightbearing post-operatively.
  • [MeSH-major] Bone Neoplasms / surgery. Calcaneus / surgery. Curettage / methods. Endoscopy. Lipoma / surgery

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  • (PMID = 18214037.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Calcium Phosphates; 0 / beta-tricalcium phosphate
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87. Liu H, Sun J, Wang Y, Yang X, Zhu E: [Repairing bone defects of benign bone neoplasm by grafting of bioactive glass combined with autologous bone marrow]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2008 Nov;22(11):1349-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Repairing bone defects of benign bone neoplasm by grafting of bioactive glass combined with autologous bone marrow].
  • OBJECTIVE: To investigate the clinical application of grafting with bioactive glass (BG) and autologous bone marrow for defect after resection and curettage of benign bone neoplasm.
  • METHODS: From January 2004 to May 2007, 34 patients with bone defects were repaired.
  • There were 14 cases of simple bone cysts, 6 cases of fibrous dysplasia, 3 cases of osteoid osteoma, 4 cases of non-ossifying fibroma, 2 cases of enchondroma and 3 cases of giant cell tumor of bone.
  • Tumor sizes varied from 2.0 cm x 1.5 cm x 1.0 cm to 9.0 cm x 3.0 cm x 2.5 cm.
  • Benign bone neoplasm was removed thoroughly with a curet or osteotome, bone defects ranged from 3.0 cm x 2.0 cm x 1.5 cm to 11.0 cm x 3.5 cm x 3.0 cm, which was closed-up with the mixtures of BG and autogenous red bone marrow.
  • The postoperative systemic and local reactions were observed, and the regular X-ray examinations were performed to observe the bone healing.
  • At averaged 16 weeks after operation, patients with bone tumor in lower limbs resumed walking independently and those with bone tumor in upper limbs resumed holding object.
  • There was no tumor recurrence during follow-up.
  • Radiographically, the interface between the implanted bone and host bone became fuzzy 1 month after implantation.
  • Two months after operation, the BG was absorbed gradually, new bone formation could be seen in the defects.
  • Four months after operation, implanted bone and host bone merged together, bone density increased.
  • Six to ten months after operation, the majority of the implanted BG was absorbed and substituted for new bone, bone remodeling was established.
  • CONCLUSION: BG may boast both bone conductive and bone inductive activities.
  • The combined grafting with BG and autologous bone marrow appears to be minimally invasive treatment to repair bone defects of benign bone neoplasm, with rare complications and no significant reverse reaction, and could repair bone defects completely.
  • [MeSH-major] Bone Marrow Transplantation. Bone Substitutes. Postoperative Complications / surgery. Reconstructive Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Bone Neoplasms / surgery. Bone and Bones / pathology. Child. Female. Follow-Up Studies. Glass. Humans. Male. Middle Aged. Transplantation, Autologous

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  • (PMID = 19068605.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Bone Substitutes
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88. Simsek A, Sipahioğlu S, Ataoğlu O, Cila E: Clear cell chondrosarcoma of the proximal femur with intrapelvic extension. Arch Orthop Trauma Surg; 2005 Feb;125(1):66-9
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  • Clear cell chondrosarcoma is a rare tumor that can be easily confused with benign tumors.
  • The aim of this report is to present a case that is rare, initially diagnosed as aneurysmal bone cyst and then chondroblastoma, and has an interesting extension pattern.
  • A 41-year-old male patient was treated for an apparently benign cystic lesion of the right proximal femur by intralesional excision and bone grafting.
  • The pathological diagnosis was aneurysmal bone cyst.
  • Both tumors were resected with a wide margin on the femoral side and a marginal margin on the intrapelvic side.
  • Again, the pathological diagnosis was chondroblastoma.
  • Clinically and pathologically, clear cell chondrosarcoma may be confused with benign bone tumors.
  • This caused a delay in the final diagnosis of this patient and he received inadequate surgical treatment, leading to a hemipelvectomy.
  • We were unable to find an exact explanation for this finding and postulated that tumor cells might have been seeded into the inner wall of the acetabulum during acetabular preparation of the total hip prosthesis.
  • [MeSH-major] Chondrosarcoma / diagnosis. Femoral Neoplasms / diagnosis. Pelvic Neoplasms / secondary. Sarcoma, Clear Cell / diagnosis

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  • (PMID = 15558292.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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89. Abdulkareem FB, Eyesan SU, Akinde OR, Ezembakwe ME, Nnodu OE: Pathological study of bone tumours at the National Orthopaedic Hospital, Lagos, Nigeria. West Afr J Med; 2007 Oct-Dec;26(4):306-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathological study of bone tumours at the National Orthopaedic Hospital, Lagos, Nigeria.
  • BACKGROUND: Although primary bone tumours are relatively uncommon, they constitute the most important tumours in patients under 20 years.
  • OBJECTIVE: To update the literature on the relative frequency and clinico-pathologic characteristics of bone tumours in this environment.
  • MATERIALS AND METHODS: The clinical and histopathological records of patients presenting with diagnosis of bone tumours between 1999 and 2004 and managed at the National Orthopaedic Hospital, Igbobi, (NOHI) Lagos, Nigeria were review and where necessary, new ones were prepared from the paraffin blocks and stained with routine haematoxylin and eosin stain.
  • RESULTS: Seventy-seven cases were recorded; 61 (79.2%) benign and 16 (15.6%) malignant.
  • The male:female ratio for all tumours was 2:1.
  • The commonest benign bone tumours were osteochondroma and giant cell tumour accounting for 52 (67%) of all cases with > 60% in males.
  • The most common primary malignant bone tumour was osteosarcoma, all in males.
  • Four (5.2%) cases of metastatic bone tumours located commonly in the proximal femur and humerus were also recorded.
  • CONCLUSION: Osteochondroma and giant cell tumours are the commonest benign tumours while osteosarcoma is the most common primary bone tumour all occurring in the first two decades of life.
  • [MeSH-major] Bone Neoplasms / pathology

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  • (PMID = 18705432.001).
  • [ISSN] 0189-160X
  • [Journal-full-title] West African journal of medicine
  • [ISO-abbreviation] West Afr J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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90. Cantwell CP, Scanlon T, Dudeney S, O'Byrne J, Eustace S: CT guided radiofrequency ablation of intra-articular osteoid osteoma of the hip. Ir J Med Sci; 2005 Jul-Sep;174(3):97-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Osteoid osteoma is a painful benign bone tumour.
  • Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner.
  • [MeSH-major] Bone Neoplasms / surgery. Catheter Ablation. Hip / physiopathology. Joint Diseases / therapy. Osteoma, Osteoid / surgery

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  • (PMID = 16285350.001).
  • [ISSN] 0021-1265
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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91. Marioni G, Marchese-Ragona R, Guarda-Nardini L, Stramare R, Tognazza E, Marino F, Staffieri A: Giant cell tumour (central giant cell lesion) of the maxilla. Acta Otolaryngol; 2006 Jul;126(7):779-81
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  • [Title] Giant cell tumour (central giant cell lesion) of the maxilla.
  • The giant cell tumour (GCT) is a benign, locally invasive lesion that accounts for about 20% of benign bone tumours.
  • Our successful maxillary reconstruction based on the association between autologous calvarial bone sticks bent with titanium miniplates and a temporalis muscle pedicled flap allowed the involvement of only one donor area for both hard and soft tissues.
  • [MeSH-major] Giant Cell Tumor of Bone / diagnosis. Giant Cell Tumor of Bone / surgery. Maxillary Neoplasms / diagnosis. Maxillary Neoplasms / surgery

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  • (PMID = 16803721.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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92. Wang J, Pei F, Tu C, Zhang H, Qiu X: Serum bone turnover markers in patients with primary bone tumors. Oncology; 2007;72(5-6):338-42
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  • [Title] Serum bone turnover markers in patients with primary bone tumors.
  • OBJECTIVES: It was the aim of this study to investigate parameters of bone turnover such as serum bone-specific alkaline phosphatase (BALP) and N-terminal midfragment of osteocalcin (N-MID), as well as serum C-terminal telopeptide of type I collagen (CTX) in patients with primary bone tumors and to investigate their validity in differentiating malignant from benign bone tumors.
  • METHODS: A total of 219 patients with primary bone tumors entered the study.
  • In each group, the patients were divided into several subgroups (osteosarcoma, benign bone tumors or tumor-like lesions, giant cell tumor, and other primary malignant bone tumors).
  • CONCLUSIONS: A high serum BALP level is valuable for the diagnosis of adult osteosarcoma, but its use in the development of a differential diagnosis in the teenage patients is not advised because serum BALP levels are also affected by age, pubertal stage and growth velocity.
  • Both serum N-MID and serum CTX are hardly useful in the differential diagnosis of primary bone tumors.
  • [MeSH-major] Alkaline Phosphatase / blood. Biomarkers, Tumor / blood. Bone Neoplasms / blood. Bone Neoplasms / metabolism

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  • [Copyright] (c) 2008 S. Karger AG, Basel
  • (PMID = 18187955.001).
  • [ISSN] 1423-0232
  • [Journal-full-title] Oncology
  • [ISO-abbreviation] Oncology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / Collagen Type I; 104982-03-8 / Osteocalcin; EC 3.1.3.1 / Alkaline Phosphatase
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93. Wallace MJ, Ross M: Bone lymphangiomatosis: treatment with percutaneous cementoplasty. Spine (Phila Pa 1976); 2005 Jun 15;30(12):E336-9
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  • [Title] Bone lymphangiomatosis: treatment with percutaneous cementoplasty.
  • OBJECTIVES: Disseminated lymphangiomatosis is a rare disorder that can produce clinical manifestation secondary to soft tissue, visceral and bone involvement.
  • The overall prognosis of this disorder is usually poor, and the current treatment options for its sequelae are limited and only palliative.
  • In this report, we present the use of cementoplasty in the percutaneous treatment of a sacral lymphangiomatous bone lesion producing severe pain.
  • SUMMARY OF BACKGROUND DATA: Disseminated lymphangiomatosis is a rare disorder that can produce clinical manifestation secondary to soft tissue, visceral, and bone involvement.
  • Computed tomography guided osteoplasty injecting acrylic bone cement into the lesion resulted in almost immediate reduction in pain.
  • The injection of bone cement into the sacral lesion was then monitored by intermittent CT imaging.
  • CONCLUSION: The case presented demonstrates the feasibility and efficacy of computed tomography-guided cementoplasty used to palliate unusual causes of benign osteolytic bone lesions.
  • [MeSH-major] Bone Cements / therapeutic use. Lymphangioma / therapy. Minimally Invasive Surgical Procedures. Orthopedic Procedures / methods. Sacrum / pathology. Spinal Neoplasms / therapy
  • [MeSH-minor] Adult. Humans. Male. Neoplasm Recurrence, Local. Osteolysis / parasitology. Osteolysis / surgery. Tomography, X-Ray Computed

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  • (PMID = 15959357.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Cements
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94. Sponer P, Urban K, Urbanová E: [Scintigraphic detection of osteoblast activity after implantation of BAS-0 bioactive glass-ceramic material into long bone defects]. Acta Chir Orthop Traumatol Cech; 2006 Jun;73(3):176-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Scintigraphic detection of osteoblast activity after implantation of BAS-0 bioactive glass-ceramic material into long bone defects].
  • PURPOSE OF THE STUDY: The aim of the study was to demonstrate, by three-phase bone scintigraphy, radionuclide uptake at the site of defects in long bones filled with the non-resorbable bioactive glass-ceramic material BAS-0 at a long follow-up.
  • MATERIAL: Twenty patients, 14 men and 6 women, operated on between 1990 and 2000 for benign bone tumors or tumor-like lesions localized in the femur, tibia or humerus were comprised in the study.
  • The diagnoses based on histological examination included juvenile bone cysts in 11, aneurysmal bone cyst in five, non-ossifying fibroma in two, and fibrous dysplasia in two patients.
  • Three-phase bone scans were made and the healthy and the affected limbs in each patient were compared by means of an index.
  • On three-phase bone scans, radionuclide distribution on the flow phase and soft tissue phase was symmetrical in both limbs of all patients.
  • This changes local mechanical signals, which has a negative effect on the adjacent bone tissue.
  • Stress accumulating at the interface of a rigid implant and bone tissue may result in pain, and is detected by scintigraphy as an increased nucleotide uptake, particularly in diaphyseal grafts.
  • [MeSH-major] Bone Diseases / therapy. Bone Substitutes. Bone and Bones / radionuclide imaging. Ceramics. Osseointegration. Prostheses and Implants

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  • (PMID = 16846563.001).
  • [ISSN] 0001-5415
  • [Journal-full-title] Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
  • [ISO-abbreviation] Acta Chir Orthop Traumatol Cech
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / BAS O glass ceramic; 0 / Bone Substitutes
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95. Zuntini M, Pedrini E, Parra A, Sgariglia F, Gentile FV, Pandolfi M, Alberghini M, Sangiorgi L: Genetic models of osteochondroma onset and neoplastic progression: evidence for mechanisms alternative to EXT genes inactivation. Oncogene; 2010 Jul 1;29(26):3827-34
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  • Osteochondroma, the most common benign bone tumor, may occur as a sporadic lesion or as multiple neoplasms in the context of multiple osteochondromas syndrome.
  • Although both benign conditions have been linked to defects in EXT1 or EXT2 genes, contradictory reports are present in the literature regarding the requirement of their biallelic inactivation for osteochondroma development.
  • Our results clearly indicate that, in most cases, biallelic inactivation of EXT genes does not account for osteochondromas formation; this mechanism should be regarded as a common feature for hereditary osteochondromas transformation and as an event that occurs later in tumor progression of solitary cases.
  • [MeSH-major] Bone Neoplasms / genetics. Gene Silencing. N-Acetylglucosaminyltransferases / genetics. Osteochondroma / genetics

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  • (PMID = 20418910.001).
  • [ISSN] 1476-5594
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
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96. Aalderink K, Wolf B: Scapular osteochondroma treated with arthroscopic excision using prone positioning. Am J Orthop (Belle Mead NJ); 2010 Feb;39(2):E11-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteochondromas, or exostoses, are common benign bone tumors.
  • [MeSH-major] Arthroscopy / methods. Bone Neoplasms / pathology. Osteochondroma / pathology. Scapula / pathology

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  • (PMID = 20396684.001).
  • [ISSN] 1934-3418
  • [Journal-full-title] American journal of orthopedics (Belle Mead, N.J.)
  • [ISO-abbreviation] Am J. Orthop.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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97. Teka A, Admassie D, Schneider J: Osteochondroma of the coccyx: a case report. Ethiop Med J; 2010 Jul;48(3):247-51
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  • Osteochondroma is the most common benign bone tumor.

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  • (PMID = 21073087.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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98. Layadi F, Aniba K, Lmejjati M, Aït Elqadi A, Aït Benali S: [Giant osteoid osteoma of the posterior skull base. A case report and literature review]. Neurochirurgie; 2006 Jun;52(2-3 Pt 1):128-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Ostéome ostéoïde géant de l'étage postérieur de la base du crâne. A propos d'un cas et revue de la littérature.
  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones.
  • Cerebral MRI shows a giant lesion of the posterior cerebral fossa with destruction of the left petrous bone and the left side of the occipital bone.
  • CONCLUSION: Although benign and rare, osteoid osteoma can present with neurological deficit due to mass effect and involvement of nervous structures especially in the posterior skull base.

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  • (PMID = 16840973.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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99. Lee VN, Nithyananth M, Cherian VM, Amritanand R, Venkatesh K, Sundararaj GD, Raghuram LN: Preoperative embolisation in benign bone tumour excision. J Orthop Surg (Hong Kong); 2008 Apr;16(1):80-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative embolisation in benign bone tumour excision.
  • PURPOSE: To assess the role of preoperative embolisation in benign bone tumour excision.
  • METHODS: 3 men and 3 women aged 19 to 35 (mean 23) years with either a giant cell tumour or an aneurysmal bone cyst in limb girdle sites underwent preoperative embolisation a day prior to wide local excision by the same surgeon.
  • Tumour size, blood loss, wound healing, infection, and tumour recurrence were assessed.
  • No tumour recurred within a minimum 5-year follow-up.
  • CONCLUSION: Preoperative embolisation is useful in the management of vascular and aggressive bone tumours located at limb girdle sites where a tourniquet cannot be used.
  • [MeSH-major] Bone Cysts, Aneurysmal / surgery. Bone Neoplasms / surgery. Embolization, Therapeutic. Giant Cell Tumor of Bone / surgery. Preoperative Care

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  • (PMID = 18453665.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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100. Arkader A, Dormans JP, Gaugler R, Davidson RS: Spontaneous regression of solitary osteochondroma: reconsidering our approach. Clin Orthop Relat Res; 2007 Jul;460:253-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteochondromas are the most common benign bone tumor; nonetheless, the natural history is poorly understood as a result of the low threshold for resection and the fact that many of these lesions are asymptomatic and therefore never diagnosed.
  • [MeSH-minor] Child. Diagnosis, Differential. Female. Humans. Remission, Spontaneous

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  • (PMID = 17620816.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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