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1. Nasser F, Affonso BB, de Jesus-Silva SG, Coelho Dde O, Zlotnik E, Messina Mde L, Baracat EC: [Uterine fibroid embolization in women with giant fibroids]. Rev Bras Ginecol Obstet; 2010 Nov;32(11):530-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Embolização de mioma uterino em mulheres portadoras de miomas volumosos.

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  • (PMID = 21271163.001).
  • [ISSN] 1806-9339
  • [Journal-full-title] Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
  • [ISO-abbreviation] Rev Bras Ginecol Obstet
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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2. Fatima S, Ahmed Z, Azam M: Benign metastasizing leiomyoma. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):802-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign metastasizing leiomyoma.
  • Benign metastasizing leiomyoma (BML) is a rare condition, affecting predominantly reproductive-age females with uterine leiomyomata and is most often associated with multiple benign-appearing smooth muscle tumors in lungs.
  • We report herein a case of a 38-year-old woman who presented with multiple uterine fibroids for which hysterectomy was carried out on her.
  • Histopathology of one of the pleura-based nodules revealed a neoplasm composed of interlacing fascicles of spindle cells with uniform nuclei.
  • The tumor cells were positive for alpha-smooth muscle actin and negative for CD34 immunohistochemical stain.

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  • (PMID = 21045423.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Antigens, CD34
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3. Ekici AI, Ekici S, Gürel B, Altinok G, Erkan I, Güngen Y: Benign mixed epithelial and stromal tumor of the kidney. ScientificWorldJournal; 2006;6:615-8
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  • [Title] Benign mixed epithelial and stromal tumor of the kidney.
  • The renal mass was found to be a benign, biphasic tumor composed of an epithelial component, consisting of ducts of variable size scattered within a mesenchymal component, composed of spindle cells arranged in sheets and fascicles.
  • The spindle component shows desmin, smooth muscle actin, and estrogen and progesterone receptor positivity immunohistochemically.
  • The diagnosis of benign mixed epithelial and stromal tumor of the kidney is rendered.
  • No recurrent disease has been detected during 2 years of follow up.

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  • (PMID = 16752009.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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4. Castro DE, Raghuram K, Phillips CD: Benign triton tumor of the trigeminal nerve. AJNR Am J Neuroradiol; 2005 Apr;26(4):967-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign triton tumor of the trigeminal nerve.
  • Benign triton tumors (neuromuscular hamartomas) are rare neoplasms composed of well-differentiated striated muscle fibers admixed with peripheral nerve fibers.
  • To the best of our knowledge, this is the third case reported in the world literature of a benign triton tumor involving cranial nerve V (trigeminal nerve) and the first in the radiology literature.
  • [MeSH-major] Hamartoma / diagnosis. Trigeminal Nerve Diseases / diagnosis

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  • (PMID = 15814954.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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5. Cîmpean AM, Raica M, Nariţa D: Diagnostic significance of the immunoexpression of CD34 and smooth muscle cell actin in benign and malignant tumors of the breast. Rom J Morphol Embryol; 2005;46(2):123-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic significance of the immunoexpression of CD34 and smooth muscle cell actin in benign and malignant tumors of the breast.
  • PURPOSE: Our aim was to investigate the distribution of CD34 and smooth muscle cell actin positive myofibroblasts in the stroma of the normal mammary gland, benign and malignant tumors.
  • RESULTS: We have found normal breast tissue, sclerosing adenosis, fibroadenomas, fibrocystic diseases, phyllodes tumor, DCIS, ductal invasive, lobular, squamous, medullary, mucinous, and papillary carcinomas.
  • All the normal breast tissues and most of benign lesions were positive for CD34 and negative for SMA.
  • The exceptions were represented by a case of fibroadenoma and the phyllodes tumor, with CD34 positivity and a focal acquisition of SMA; fibrocystic disease with associated apocrine metaplasia adjacent to a squamous carcinoma with loss of CD34 expression and focal acquisition of SMA.
  • CONCLUSIONS: Although there were some exceptions especially when one of the two markers was interpreted separately and in some cases associated with sclerotic stroma, we conclude that the combined expression of CD34 and a-SMA is of potential diagnostic value in the distinction between benign and malignant tumors in some difficult cases.
  • [MeSH-major] Actins / analysis. Antigens, CD34 / analysis. Breast Neoplasms / pathology. Muscle, Smooth / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, CD / analysis. Biopsy. Carcinoma, Ductal / pathology. Female. Fibrocystic Breast Disease / pathology. Humans. Middle Aged. Neoplasm Invasiveness. Smad Proteins / analysis

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  • (PMID = 16286998.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Smad Proteins
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6. Vázquez Camacho EE, Cabrera Carranco E, Sánchez Herrera RG: [Pedunculated twisted myoma and pregnancy. Case report]. Ginecol Obstet Mex; 2009 Sep;77(9):441-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pedunculated twisted myoma and pregnancy. Case report].
  • [Transliterated title] Mioma pediculado torcido en una mujer embarazada. Reporte de caso.
  • The detection of a pelvic mass during pregnancy is uncommon.
  • We report a case of a woman at the 15 week of gestation with torsi6n of a pedunculated mioma mimicking in the ultrasonografic image an ovarian tumor.

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  • (PMID = 19899435.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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7. Costa Benavente L, Silva Barroso F, Avila Flores E: [Giant uterine myoma]. Ginecol Obstet Mex; 2005 Oct;73(10):563-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant uterine myoma].
  • [Transliterated title] Mioma uterino gigante.
  • We report the case of a 45-year old woman with a large abdominal mass and three-day history of constipation and respiratory difficulty.
  • Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed, and a giant uterine myoma, which weighted 12.4 kg (27.3 lb), was found.

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  • (PMID = 16583838.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 7
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8. Pérez-Cejudo JA, Piqué E, Arduan I, Palacios S, Sánchez C, Rodríguez M, Morales R: [Umbilical cutaneous endometriosis associated with a large uterine myoma]. Actas Dermosifiliogr; 2005 Jan-Feb;96(1):43-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Umbilical cutaneous endometriosis associated with a large uterine myoma].
  • [Transliterated title] Endometriosis cutánea umbilical asociada a mioma uterino gigante.
  • The Dermatology Department was consulted because of an asymptomatic umbilical tumor which had been developing for 5 years.
  • [MeSH-major] Endometriosis / complications. Leiomyoma / complications. Skin Diseases / complications. Umbilicus. Uterine Neoplasms / complications


9. Hrgović Z, Kulas T, Habek D, Izetbegović S, Hrgović I: [New options in the diagnosis and management of uterine myoma]. Med Arh; 2008;62(4):234-9
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  • [Title] [New options in the diagnosis and management of uterine myoma].
  • [Transliterated title] Nove mogućnosti u dijagnostici i lijecenju mioma maternice.
  • Myoma accounts for nearly 95% of all benign tumors of female genital organs and is the most common neoplasm of female genital tract.
  • Along with thorough history and gynecologic examination, ultrasound study is of utmost importance in the diagnosis of myoma; magnetic resonance (MR) study may also be required in rare cases.
  • A number of therapeutic options are available for the management of myoma, ranging from medicamentous therapy through operative procedures (e.g., total or supracervical hysterectomy or myoma enucleation) and novel non-operative procedures (e.g., embolization of uterine artery (EUA) and magnetic resonance guided focused ultrasound (MRgFUS).
  • Discomforts caused by a myoma are an absolute indication for treatment.
  • Therapeutic option to be chosen is determined by the number, size and location of myomas, and the patient's preferences.

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  • (PMID = 19145810.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Bosnia and Herzegovina
  • [Number-of-references] 61
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10. Squillaci S, Cecchetti D, Tallarigo F, Pontieri F, Filardo AV: [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature]. Pathologica; 2005 Dec;97(6):378-82
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  • [Title] [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature].
  • [Transliterated title] Mioma perivascolare di tipo miopericitoma dei tessuti molli del piede: descrizione di un caso e revisione della letteratura.
  • We describe a rare case of myopericytoma-type perivascular myoma (MTPM) which arose in acral location and the literature on this field is briefly reviewed.
  • Immunohistochemically, the neoplastic cells were positive for vimentin, smooth muscle actin, desmin and calponin, negative for S-100 protein, CD34, CD31 and cytokeratins (AE1/AE3, Cam 5.2).
  • [MeSH-major] Foot Diseases / pathology. Myoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16619980.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 16
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11. Sinici E, Tunay S, Kiliç E, Erler K, Altinmakas M: [Psychological evaluation of patients with benign musculoskeletal system tumors]. Acta Orthop Traumatol Turc; 2006;40(3):199-201
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  • [Title] [Psychological evaluation of patients with benign musculoskeletal system tumors].
  • [Transliterated title] Benign kas-iskelet sistemi tümörü olan hastalarda psikolojik durum değerlendirmesi.
  • OBJECTIVES: This study was designed to determine to what extent psychological status was affected by sociodemographic characteristics and by being informed about the diagnosis in patients with benign musculoskeletal tumors.
  • METHODS: The study included 112 male patients (mean age 23.8 years; range 20 to 35 years) who were hospitalized for benign tumors of the musculoskeletal system.
  • RESULTS: The depression level was not correlated with the localization (upper or lower extremity) of the musculoskeletal system tumor, the marital status of the patient, and the presence or absence of knowledge of the patient about the diagnosis (p>0.05).
  • [MeSH-major] Anxiety Disorders. Bone Neoplasms / psychology. Muscle Neoplasms / psychology

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  • (PMID = 16905891.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Turkey
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12. Leuschner I: [Inflammatory myofibroblastic tumor]. Pathologe; 2010 Mar;31(2):106-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Inflammatory myofibroblastic tumor].
  • [Transliterated title] Inflammatorischer myofibroblastischer Tumor.
  • Inflammatory myofibroblastic tumor (IMT) is a soft tissue lesion which can be found in almost all parts of the human body, but shows the highest incidence in the abdomen.
  • The tumors are associated with a benign behavior but recurrences occur in about one third of abdominal cases.
  • [MeSH-major] Granuloma, Plasma Cell / pathology. Neoplasms, Muscle Tissue / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Abdominal Neoplasms / genetics. Abdominal Neoplasms / pathology. Biomarkers, Tumor / genetics. Child. Diagnosis, Differential. Humans. Prognosis. Protein-Tyrosine Kinases / genetics. Receptor Protein-Tyrosine Kinases

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  • [Cites] Semin Diagn Pathol. 1998 May;15(2):102-10 [9606802.001]
  • [Cites] Am J Surg Pathol. 2007 Apr;31(4):509-20 [17414097.001]
  • [Cites] Am J Surg Pathol. 2006 Dec;30(12):1502-12 [17122505.001]
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  • [Cites] Am J Surg Pathol. 1991 Dec;15(12):1146-56 [1746682.001]
  • (PMID = 20063099.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases; EC 2.7.10.1 / anaplastic lymphoma kinase
  • [Number-of-references] 6
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13. Clauss S, Höller S, Hegi L, Blum R, Hösli I: ["STUMP" (smooth muscle tumour of uncertain malignant potential), a tumour of the uterus in pregnancy--a diagnostic and therapeutic challenge]. Z Geburtshilfe Neonatol; 2010 Apr;214(2):74-7
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  • [Title] ["STUMP" (smooth muscle tumour of uncertain malignant potential), a tumour of the uterus in pregnancy--a diagnostic and therapeutic challenge].
  • [Transliterated title] "STUMP" (smooth muscle tumor of uncertain malignant potential), ein Uterustumor in der Schwangerschaft, eine diagnostische und therapeutische Herausforderung.
  • We present the case of a preterm birth in the 27 (th) week of gestation, probably due to a chorionamnionitis, with the coincidental finding of a STUMP (smooth muscle tumour of uncertain malignant potential).
  • The STUMP is a rare tumour entity characterised by smooth muscle cells which is difficult to classify by means of histology.
  • The WHO classification of mesenchymal tumours allocates STUMP as an intermediate tumour between a benign leiomyoma and a malignant leiomyosarcoma.
  • If histological criteria of malignancy are not fulfilled because the type of necrosis is in doubt or the interpretation of mitotic figures is ambiguous and the tumour cannot reliably be classified as a leiomyoma, it is classified as a STUMP.
  • Compared to malignant leiomyosarcoma, STUMP has a superior prognosis, but the biological potential of the tumour remains unclear; lymphogenic and haematogenic dissemination seems possible even after a long period of time.
  • We present the first description of a case of STUMP during pregnancy, raising the question of whether the histological finding in tumours of the uterus during pregnancy are important.
  • [MeSH-major] Smooth Muscle Tumor / diagnosis. Smooth Muscle Tumor / therapy. Uterine Neoplasms / diagnosis. Uterine Neoplasms / therapy

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  • (PMID = 20411475.001).
  • [ISSN] 1439-1651
  • [Journal-full-title] Zeitschrift für Geburtshilfe und Neonatologie
  • [ISO-abbreviation] Z Geburtshilfe Neonatol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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14. Sousa V, Carvalho L: [Glomic tumor: presentation of an infrequent case]. Rev Port Pneumol; 2006 May-Jun;12(3):269-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Glomic tumor: presentation of an infrequent case].
  • [Transliterated title] Tumor glómico do pulmão: Apresentação de um caso pouco frequente.
  • Glomic tumours are perivascular tumours whose cells resemble modified smooth muscular cells of the glomic body.
  • The authors present a case of a 62 year old women with left thoracic pain and great enforces dyspnoea.
  • Glomic tumours are generally benign.
  • They should be classified as glomic tumor, glomangioma and glomangiomioma according to the relative abundance of glomic cells and of the vascular and muscular components.
  • The differential diagnosis of glomic tumours of the lung includes the carcinoid, hemangioperycitoma, smooth muscle tumours (epithelioid leyomioma) and the paraganglioma.
  • [MeSH-major] Glomus Tumor / diagnosis. Lung Neoplasms / diagnosis

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  • (PMID = 16967176.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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15. Aranda C, Sotelo M, Torres A, Zárate M: [Phyllodes tumor and pregnancy. A report of a case]. Ginecol Obstet Mex; 2005 Jul;73(7):387-92
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  • [Title] [Phyllodes tumor and pregnancy. A report of a case].
  • [Transliterated title] Tumor phyllodes y embarazo. Reporte de un caso.
  • Phyllodes tumor is a rare breast fibroepithelial neoplasm of the breast, predominant in females (0.3 to 0.5%).
  • Phyllodes tumor during pregnancy grows fast and its size is relatively big.
  • These tumors can be classified as benign, malignant or neighboring.
  • A possible phyllodes tumour in the right breast was observed during surgery, weight 9.6 pounds, with partial infiltration to major pectoral muscle.
  • Pathology reported a benign phyllodes tumor in the right breast, with surgical borders free of tumor.
  • Phyllodes tumor is rare and can occur during pregnancy.
  • It is unknown if the tumor is hormone-dependent.
  • The growth of a tumor on a subsequent pregnancy is not necessarily associated with recurrency or with a new disorder on the patient, who has had a complete excision.
  • [MeSH-major] Breast Neoplasms. Phyllodes Tumor. Pregnancy Complications, Neoplastic

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  • (PMID = 16304962.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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16. Palmara V, Triolo O, Benedetto V, Lo Re C, Sturlese E, Retto G, Santoro G: Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate. Gynecol Obstet Invest; 2010;69(2):131-5
Hazardous Substances Data Bank. LEUPROLIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate.
  • AIM: We studied morphologic modifications of the endometrium induced by leuprorelin acetate, a gonadotropin-releasing hormone agonist, in women with uterine myomata.
  • RESULTS: A near-normal endometrium was observed after 2 months of therapy, while treatment with 6 cycles of leuprorelin acetate induced a uniform morphologic regression of the uterine mucosa.


17. McLucas B, Chespak L, Kaminsky D: Myoma necrosis following Gelfoam embolization of uterine myomata. Minim Invasive Ther Allied Technol; 2008;17(3):200-4
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  • [Title] Myoma necrosis following Gelfoam embolization of uterine myomata.

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  • (PMID = 18666018.001).
  • [ISSN] 1365-2931
  • [Journal-full-title] Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
  • [ISO-abbreviation] Minim Invasive Ther Allied Technol
  • [Language] eng
  • [Publication-type] Comparative Study; Controlled Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemostatics
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18. Kamarashev J, French LE, Dummer R, Kerl K: Symplastic glomus tumor - a rare but distinct benign histological variant with analogy to other 'ancient' benign skin neoplasms. J Cutan Pathol; 2009 Oct;36(10):1099-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symplastic glomus tumor - a rare but distinct benign histological variant with analogy to other 'ancient' benign skin neoplasms.
  • Histologically, a well-circumscribed tumor of 3 mm diameter was found in the dermis.
  • Multinuclear cells were present as were numerous small-to-medium vessels throughout the tumor.
  • The tumor stroma showed myxoid areas.
  • Immunohistochemistry showed cytoplasmic and membranous expression of smooth muscle actin and vimentin.
  • The histological features and immunoprofile were consistent with the diagnosis of symplastic glomus tumor, a rare histological variant, which has been defined as a glomus tumor exhibiting marked nuclear atypia, in the absence of any other criteria for malignancy.
  • The biological behavior of the tumor is benign.
  • It is essential to differentiate this entity from malignant glomus tumor, which has metastatic potential.
  • Even prominent cellular atypia and nuclear pleomorphism in a glomus tumor as in our case is not a marker of malignancy in the absence of additional criteria.
  • [MeSH-major] Fingers / pathology. Glomus Tumor / pathology. Skin Neoplasms / pathology

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19602065.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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19. Porter GJ, Evans AJ, Lee AH, Hamilton LJ, James JJ: Unusual benign breast lesions. Clin Radiol; 2006 Jul;61(7):562-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual benign breast lesions.
  • The purpose of this article is to show examples of the radiological (mammography and/or ultrasound) and pathological appearances of unusual benign breast lesions.
  • The article includes the first published description of the ultrasound appearance of a myofibroblastoma.
  • [MeSH-minor] Fasciitis / radiography. Fasciitis / ultrasonography. Female. Fibroma / radiography. Fibroma / ultrasonography. Granular Cell Tumor / radiography. Granular Cell Tumor / ultrasonography. Hemangioma / radiography. Hemangioma / ultrasonography. Humans. Leiomyoma / radiography. Leiomyoma / ultrasonography. Mammography / methods. Neoplasms, Muscle Tissue / radiography. Neoplasms, Muscle Tissue / ultrasonography. Neurofibroma / radiography. Neurofibroma / ultrasonography. Ultrasonography, Mammary / methods

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  • (PMID = 16784941.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 26
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20. Román-Díaz J, Alayón-Laguer D, Fernández Nelson M, Luis B, Caceres-Perkins W, Conde-Sterling D: Rare benign breast tumor. Bol Asoc Med P R; 2010 Apr-Jun;102(2):50-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare benign breast tumor.
  • We report the case of a female patient with an incidental finding at routine mammography evaluation which consisted of a benign spindle cell tumor, namely Breast Myofibroblastoma.
  • It is arranged in fascicles with interspersed broad bands of hyalinized collagen with variable immunohistochemical reactivity to desmin, vimentin, smooth muscle actin and CD 34.
  • It is important to recognize the benign nature of this neoplasm to prevent extensive mutilating surgical procedures.
  • [MeSH-major] Breast Neoplasms / pathology. Neoplasms, Muscle Tissue / pathology

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  • (PMID = 20939206.001).
  • [ISSN] 0004-4849
  • [Journal-full-title] Boletín de la Asociación Médica de Puerto Rico
  • [ISO-abbreviation] Bol Asoc Med P R
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Puerto Rico
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21. Durgun Y, Firat C, Miman MC, Kirimlioglu H: A rare benign laryngeal tumor: angiomyolipoma. J Craniofac Surg; 2010 Nov;21(6):1956-7

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  • [Title] A rare benign laryngeal tumor: angiomyolipoma.
  • Angiomyolipoma is a mesenchymal neoplasm containing adipose tissue, blood vessels, and smooth muscle fibers.
  • Arising most frequently in the kidney, the tumor may exceptionally be at the head and neck region.
  • The tumor was removed by an endolaryngeal approach.

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  • (PMID = 21119467.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Nucci MR, Drapkin R, Dal Cin P, Fletcher CD, Fletcher JA: Distinctive cytogenetic profile in benign metastasizing leiomyoma: pathogenetic implications. Am J Surg Pathol; 2007 May;31(5):737-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distinctive cytogenetic profile in benign metastasizing leiomyoma: pathogenetic implications.
  • "Benign metastasizing leiomyoma" is the terminology used to describe a controversial entity characterized by a proliferation of bland-appearing smooth muscle in lung or abdominopelvic lymph nodes.
  • In this report, we describe 5 cases of pulmonary-based smooth muscle tumors that are clinically and histologically consistent with this entity, and in which we identified consistent chromosomal aberrations (19q and 22q terminal deletion in all cases).
  • This cytogenetic profile is found in approximately 3% of uterine leiomyoma, but has not been described in other types of benign or malignant neoplasia.
  • These findings suggest that the nodular pulmonary smooth muscle proliferations termed "benign metastasizing leiomyoma," are a genetically distinct entity, which likely originate from a biologically distinctive subset of uterine leiomyoma.
  • [MeSH-minor] Actins / analysis. Biomarkers, Tumor. Chromosome Deletion. Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Desmin / analysis. Female. Humans. Karyotyping. Middle Aged. Neoplasm Metastasis

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  • (PMID = 17460458.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin
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23. Bierer S, Wülfing C, Bode ME, Pühse G, Brinkmann OA, Hertle L: [Bilateral renal angiomyolipomas with a thrombus in the inferior caval vein. Rare growth pattern of a benign tumor]. Urologe A; 2005 Dec;44(12):1469-72
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  • [Title] [Bilateral renal angiomyolipomas with a thrombus in the inferior caval vein. Rare growth pattern of a benign tumor].
  • [Transliterated title] Bilaterale renale Angiomyolipome mit Thrombus in der Vena cava inferior. Seltenes Wachstumsverhalten eines benignen Tumors.
  • Renal angiomyolipomas are mesenchymal tumors that are composed of fat tissue, smooth muscle cells and vessels.
  • These are benign tumors, but in rare cases they show a more aggressive growth pattern with invasion into the venous system but without revealing any signs of malignancy.
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Invasiveness

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  • [Cites] Nihon Hinyokika Gakkai Zasshi. 2002 Jan;93(1):48-51 [11842540.001]
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  • (PMID = 16133230.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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24. D'Armiento J, Imai K, Schiltz J, Kolesnekova N, Sternberg D, Benson K, Pardo A, Selman M, Smolarek T, Vundavalli M, Sonnet J, Szabolcs M, Chada K: Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis. Cancer Res; 2007 Mar 1;67(5):1902-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis.
  • Previously, HMGA2 was shown to be misexpressed in a number of benign, differentiated mesenchymal tumors including lipomas, uterine leiomyomas, and pulmonary chondroid hamartomas.
  • Here, we show that HMGA2 is misexpressed in pulmonary lymphangiomyomatosis (LAM), a severe disorder of unknown etiology consisting of lymphatic smooth muscle cell proliferation that results in the obstruction of airways, lymphatics, and vessels.
  • In contrast, HMGA2 was not expressed in sections of normal adult lung or other proliferative interstitial lung diseases, indicating that the expression of HMGA2 in LAM represents aberrant gene activation and is not due solely to an increase in cellular proliferation.
  • In vivo studies in transgenic mice show that misexpression of HMGA2 in smooth muscle cells resulted in increased proliferation of these cells in the lung surrounding the epithelial cells.
  • Therefore, similar to the other mesenchymal neoplasms, HMGA2 misexpression in the smooth muscle cell leads to abnormal proliferation and LAM tumorigenesis.
  • [MeSH-minor] Animals. Female. Humans. In Situ Hybridization, Fluorescence. Lung / embryology. Lung / metabolism. Mice. Mice, Inbred C57BL. Mice, Inbred CBA. Mice, Transgenic. Myocytes, Smooth Muscle / metabolism


25. Ziadé D, Achkouty R, Mrad R: [Severe hyponatremia associated with transcervical resection of a uterine myoma]. Can J Anaesth; 2009 Apr;56(4):316-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Severe hyponatremia associated with transcervical resection of a uterine myoma].
  • [Transliterated title] Hyponatrémie sévère au cours d'une résection endoscopique d'un myome utérin.
  • CLINICAL FEATURES: A 31-year old female patient underwent transcervical resection of a uterine myoma under general anesthesia.
  • CONCLUSIONS: The resorption syndrome during transcervical resection of a uterine myoma is linked to the passage into the blood of the irrigation fluid that contains glycine.

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  • [CommentIn] Can J Anaesth. 2010 Feb;57(2):181-2 [19904578.001]
  • (PMID = 19252964.001).
  • [ISSN] 0832-610X
  • [Journal-full-title] Canadian journal of anaesthesia = Journal canadien d'anesthésie
  • [ISO-abbreviation] Can J Anaesth
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] TE7660XO1C / Glycine
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26. Harper L, Lavrand F, Le Bail B, Brun M, Ferron S, Oses P, Vergnes P: Glomus tumor of the mesocolon. J Pediatr Surg; 2005 Oct;40(10):e37-8

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  • [Title] Glomus tumor of the mesocolon.
  • Glomus tumors are rare distinctive benign neoplasms, which arise from modified smooth muscle cells of the normal glomus body and are most commonly located in the subungual region of the finger.
  • We report a case of glomus tumor of the mesocolon in a 10-year-old girl.
  • Histopathology showed it to be a glomus tumor of the mesocolon.
  • [MeSH-major] Glomus Tumor. Mesocolon. Peritoneal Neoplasms

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  • (PMID = 16226974.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Asciutto G, Mumme A, Marpe B, Hummel T, Asciutto KC, Geier B: Deep venous thrombosis in a patient with large uterine myomata. Case report. Minerva Ginecol; 2008 Oct;60(5):451-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep venous thrombosis in a patient with large uterine myomata. Case report.
  • Computed tomography revealed an inhomogenous uterine enlargement due to multiple myomata producing a thrombotic occlusion of the left iliac veins.
  • Uterine myomata rarely cause acute iliac vein thrombosis due to direct compression.


28. Mavroudis K, Aloumanis K, Papapetrou PD, Voros D, Spanos I: Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle. Fertil Steril; 2007 Jun;87(6):1468.e13-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle.
  • OBJECTIVE: Virilization due to androgen-secreting neoplasms in women is a result of androgen overproduction from benign or malignant tumors that are found in the ovaries or rarely in the adrenal glands.
  • We describe a very rare case of an ectopic androgen-producing adrenal tumor.
  • RESULT(S): An ectopic mass was detected behind the left iliopsoas muscle.
  • CONCLUSION(S): This case illustrates difficulties in detecting and localizing the rare contingence of an ectopic adrenocortical androgen-secreting tumor.
  • [MeSH-major] Adrenal Gland Neoplasms / surgery. Muscle, Skeletal. Virilism / etiology

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  • (PMID = 17368455.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Ramos-Font C, Santiago Chinchilla A, Rebollo Aguirre AC, Rodríguez Fernández A, Medina Benítez A, Llamas Elvira JM: [Desmoid tumor of the thoraco-abdominal wall characterized with 18F-fluorodeoxyglucose PET/ CT scan. Correlation with magnetic resonance and bone scintigraphy. Review of the literature]. Rev Esp Med Nucl; 2009 Mar-Apr;28(2):70-3
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  • [Title] [Desmoid tumor of the thoraco-abdominal wall characterized with 18F-fluorodeoxyglucose PET/ CT scan. Correlation with magnetic resonance and bone scintigraphy. Review of the literature].
  • [Transliterated title] Tumor desmoide de la pared torácico-abdominal. Caracterización con PET-TAC con 18F-fluorodesoxiglucosa y correlación con resonancia magnética y gammagrafía ósea. Revisión de la literatura.
  • Desmoid tumours are uncommon benign tumours but with aggressive behaviour, resulting from the proliferation of well-differentiated fibroblasts.
  • When planning treatment, it is important to assess the correct tumour extent to permit curative radical surgery minimizing possible local recurrence.
  • We present the case of a patient with a desmoid tumour of the abdominal-chest wall and we review the related literature.
  • [MeSH-major] Abdominal Neoplasms / radionuclide imaging. Abdominal Wall / radionuclide imaging. Bone Neoplasms / radionuclide imaging. Fibromatosis, Aggressive / radionuclide imaging. Fluorine Radioisotopes. Fluorodeoxyglucose F18. Muscle Neoplasms / radionuclide imaging. Positron-Emission Tomography. Radiopharmaceuticals. Rectus Abdominis / radionuclide imaging. Ribs / radionuclide imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Thoracic Wall / pathology. Thoracic Wall / radiography. Thoracic Wall / radionuclide imaging

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  • (PMID = 19406052.001).
  • [ISSN] 0212-6982
  • [Journal-full-title] Revista española de medicina nuclear
  • [ISO-abbreviation] Rev Esp Med Nucl
  • [Language] spa
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 22
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30. Renner SP, Strick R, Fasching PA, Oeser S, Oppelt P, Mueller A, Beckmann MW, Strissel PL: Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk. Am J Obstet Gynecol; 2008 Dec;199(6):648.e1-9
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  • [Title] Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk.
  • OBJECTIVE: Uterine benign leiomyomas result from proliferation of a single smooth-muscle cell and their growth is affected by steroid hormones via steroid hormone receptors.
  • This investigation analyzed the +331G/A and the V600L single nucleotide polymorphisms in the progesterone receptor, and correlated their incidence with clinical and tumor parameters as well as disease risk.
  • RESULTS: No correlation was found for both single nucleotide polymorphisms or the risk for developing myoma; however, statistical significant associations were found for single nucleotide polymorphism genotypes with specific clinical and tumor characteristics, eg, endometriosis, number of live births, menstrual cycle disorder, and leiomyoma focality.
  • CONCLUSION: Our findings support that specific genotypes in the progesterone receptor may be involved in tumor growth and metastasis but not in tumor initiation.
  • [MeSH-major] Genetic Predisposition to Disease / epidemiology. Leiomyoma / genetics. Polymorphism, Single Nucleotide. Receptors, Progesterone / genetics. Uterine Neoplasms / genetics

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  • (PMID = 18691687.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Progesterone
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31. de Moraes Schenka NG, Schenka AA, de Souza Queiroz L, de Almeida Matsura M, Alvarenga M, Vassallo J: p63 and CD10: reliable markers in discriminating benign sclerosing lesions from tubular carcinoma of the breast? Appl Immunohistochem Mol Morphol; 2006 Mar;14(1):71-7
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  • [Title] p63 and CD10: reliable markers in discriminating benign sclerosing lesions from tubular carcinoma of the breast?
  • The immunohistochemical detection of myoepithelial cells in benign sclerosing lesions of the breast is useful in distinguishing them from tubular carcinoma.
  • So far, this detection has been carried out using antibodies against cytoskeletal proteins, such as alpha-smooth muscle actin (1A4) and calponin.
  • However, the specificity of these markers has been questioned since they may be expressed in stromal myofibroblasts and vascular smooth muscle.
  • The authors assessed the use of p63 and CD10 in the differential diagnosis between benign sclerosing lesions, such as sclerosing adenosis and radial scar, and tubular carcinoma, in comparison to the traditional myoepithelial markers 1A4 and calponin. p63, CD10, 1A4, and calponin were expressed in myoepithelial cells of all benign lesions and were consistently negative in all cases of tubular carcinoma.
  • In conclusion, p63 and CD10 may be used as a complement to 1A4 in distinguishing benign sclerosing lesions from tubular carcinoma of the breast.

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  • (PMID = 16540734.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; EC 3.4.24.11 / Neprilysin
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32. Dragoumis D, Atmatzidis S, Chatzimavroudis G, Lakis S, Panagiotopoulou K, Atmatzidis K: Benign spindle cell tumor not otherwise specified (NOS) in a male breast. Int J Surg Pathol; 2010 Dec;18(6):575-9
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  • [Title] Benign spindle cell tumor not otherwise specified (NOS) in a male breast.
  • Breast spindle cell tumors (BSCTs), although uncommon, constitute a heterogeneous group of benign and malignant lesions, often necessitating different therapeutic approaches.
  • This study describes the case of a 62-year-old man who displayed a gradually growing retroareolar tumor of the left breast.
  • Immunohistochemically, the mass expressed strong and diffuse cytoplasmic staining for vimentin, CD34, CD10, and bcl-2, whereas it was negative for cytokeratins, smooth muscle actin, desmin, S-100 protein, p53, Ki-67, estrogen and progesterone receptors.
  • Diverse histological results and immunohistochemical features established the diagnosis of benign BSCT, not otherwise specified.
  • The patient remains disease-free 12 months after lumpectomy.
  • This case report adds to the spectrum of the benign BSCTs and delineates the nature of different types of these lesions, in order to carefully select optimal therapeutic regimes.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 19064588.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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33. Cui Y, Tian M, Zong M, Teng M, Chen Y, Lu J, Jiang J, Liu X, Han J: Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma. Pancreatology; 2009;9(1-2):89-98
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  • [Title] Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma.
  • BACKGROUND: Dual expression of potential biomarkers in both benign and malignant pancreatic tumors was a major obstacle in the development of diagnostic biomarkers of early pancreatic cancer.
  • METHODS: To better understand the limitations of potential protein biomarkers in pancreatic cancer, we employed two-dimensional difference gel electrophoresis technology and tandem mass spectrometry to study protein expression profiles in pancreatic cancer tissues, benign pancreatic adenoma and normal adjacent pancreas.
  • RESULTS: 21 spots were overexpressed and 24 spots were downexpressed in pancreatic cancer compared with benign and normal adjacent tissues.
  • Our study demonstrated that three candidate pancreatic ductal adenocarcinoma biomarkers identified in previous studies, fructose-bisphosphate aldolase A, alpha-smooth muscle actin and vimentin, were also overexpressed in pancreatic cystadenoma, which might lower their further utility as biomarkers for pancreatic cancer.
  • Aflatoxin B(1) aldehyde reductase (AKR7A2) was confirmed to be only highly expressed in pancreatic cancer, not in normal adjacent pancreas and benign tumors.
  • [MeSH-major] Aldehyde Reductase / biosynthesis. Biomarkers, Tumor / analysis. Carcinoma, Pancreatic Ductal / metabolism. Cystadenoma / metabolism. Pancreas / metabolism. Pancreatic Neoplasms / metabolism

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  • [Copyright] Copyright 2008 S. Karger AG, Basel and IAP.
  • (PMID = 19077459.001).
  • [ISSN] 1424-3911
  • [Journal-full-title] Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
  • [ISO-abbreviation] Pancreatology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chaperonin 60; 0 / Intracellular Signaling Peptides and Proteins; 0 / Nuclear Proteins; 0 / Oncogene Proteins; 0 / PARK7 protein, human; 0 / Vimentin; 117896-08-9 / nucleophosmin; EC 1.1.1.- / aflatoxin B1 aldehyde reductase; EC 1.1.1.21 / Aldehyde Reductase; EC 4.1.2.13 / Fructose-Bisphosphate Aldolase
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34. Saeed AS, Hanaa B, Faisal AS, Najla AM: Cotyledonoid dissecting leiomyoma of the uterus: a case report of a benign uterine tumor with sarcomalike gross appearance and review of literature. Int J Gynecol Pathol; 2006 Jul;25(3):262-7
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  • [Title] Cotyledonoid dissecting leiomyoma of the uterus: a case report of a benign uterine tumor with sarcomalike gross appearance and review of literature.
  • Cotyledonoid dissecting leiomyoma (Sternberg tumor) is a very rare variant of uterine smooth muscle tumor with an unusual and alarming gross appearance.
  • An intraoperative frozen section was requested, and a diagnosis of a benign smooth muscle tumor was given.
  • Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed with removal of the pelvic tumor extension.
  • Thorough tumor sampling was performed and showed nodules of interlacing bundles of bland-looking smooth muscle cells, separated by expanded, edematous, and highly vascularized stroma.
  • Immunohistochemical studies confirmed the smooth muscle nature of the tumor.
  • [MeSH-minor] Actins / analysis. Adult. Antigens, CD34 / analysis. Female. Frozen Sections. Humans. Proto-Oncogene Proteins c-kit / analysis. Receptors, Progesterone / analysis. Sarcoma / chemistry. Sarcoma / diagnosis. Sarcoma / pathology. Smooth Muscle Tumor / chemistry. Smooth Muscle Tumor / diagnosis. Smooth Muscle Tumor / pathology

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  • (PMID = 16810065.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Receptors, Progesterone; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Number-of-references] 13
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35. Ozcan C, Görür K, Talas D, Aydin O: Intramuscular benign lipoma of the sternocleidomastoid muscle: a rare cause of neck mass. Eur Arch Otorhinolaryngol; 2005 Feb;262(2):148-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramuscular benign lipoma of the sternocleidomastoid muscle: a rare cause of neck mass.
  • Intramuscular benign lipoma commonly is found on the extremities, but is extremely rare in the head and neck region.
  • Intramuscular type lipomas arise between the muscle fibers and pass through the intermuscular septa, infiltrating the surrounding tissue.
  • A 29-year-old male patient presented with the complaint of a painless and slowly growing lateral neck mass on the left side.
  • Physical examination revealed a 4x5-cm mass adjacent to the sternocleidomastoid (SCM) muscle.
  • CT examination revealed a lobulated, well-circumscribed 5.5x2.5-cm diameter mass with adipose tissue signal density inside the SCM muscle.
  • Complete removal of the tumor can only succeed if planned and performed after a thorough preoperative clinical and radiological assessment in order to prevent recurrences.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Lipoma / pathology. Muscle Neoplasms / pathology. Neck Muscles / pathology

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  • [Cites] Otolaryngol Head Neck Surg. 2001 Dec;125(6):658-60 [11743474.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1988 Dec;114(12):1480-2 [3190880.001]
  • [Cites] J Oral Maxillofac Surg. 2002 Apr;60(4):449-50 [11928107.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1999 Jan 25;47(1):91-5 [10206400.001]
  • [Cites] J Laryngol Otol. 2002 May;116(5):395-7 [12081004.001]
  • [Cites] Cancer. 1974 Mar;33(3):732-8 [4815576.001]
  • [Cites] Head Neck Surg. 1980 Nov-Dec;3(2):145-68 [7002869.001]
  • [Cites] Laryngoscope. 1983 Feb;93(2):205-7 [6823193.001]
  • [Cites] Laryngoscope. 1978 May;88(5):839-48 [642677.001]
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  • [Cites] AJNR Am J Neuroradiol. 1986 Jul-Aug;7(4):657-64 [3088944.001]
  • (PMID = 15197561.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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36. Saad RS, Liu YL, Silverman JF: Distribution of basal/myoepithelial markers in benign and malignant bronchioloalveolar proliferations of the lung. Appl Immunohistochem Mol Morphol; 2010 May;18(3):219-25
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  • [Title] Distribution of basal/myoepithelial markers in benign and malignant bronchioloalveolar proliferations of the lung.
  • We investigated the staining pattern of commonly used basal cell/myoepithelial markers, such as p63 (a p53-homologous nuclear protein), basal cell-specific cytokeratin antibody (34betaE12, K903), and smooth muscle myosin heavy chain (SMMHC) in benign and malignant bronchioloalveolar proliferations of the lung.
  • We studied 85 lung lesions consisting of 35 bronchioloalveolar carcinoma, 30 well-differentiated adenocarcinoma, and 20 cases of benign lung lesions.

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  • (PMID = 20065853.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CKAP4 protein, human; 0 / Membrane Proteins; 68238-35-7 / Keratins; EC 3.6.1.- / Smooth Muscle Myosins
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37. Jin MS, Ha HJ, Baek HJ, Lee JC, Koh JS: Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report. Acta Cytol; 2008 May-Jun;52(3):357-60
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  • [Title] Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report.
  • BACKGROUND: Typical cytologic features of pulmonary hamartoma (PH) are usually smears of hyaline cartilage, fibrous tissue, smooth muscle, adipocytic components and respiratory epithelium.
  • Cytologic features of adenomyomatous hamartoma, a special variant of PH, are not documented in the literature and are confused with epithelial neoplasm in the case of sparse stromal cellularity.
  • Fine needle aspiration biopsy (FNAB) revealed numerous mucinous epithelial cells presenting predominantly in cohesive cellular sheets that suggested benign mucinous epithelial lesion.
  • The patient underwent surgery for the tumor, and it was histologically proven to be an adenomyomatous hamartoma.

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  • (PMID = 18540306.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Rakhshani N, Hormazdi M, Abolhasani M, Shahzadi M: Benign metastasizing leiomyoma of the uterus. Arch Iran Med; 2007 Jan;10(1):97-9
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  • [Title] Benign metastasizing leiomyoma of the uterus.
  • Herein, we report on a well-characterized benign metastasizing leiomyoma, presented in an unusual site.
  • Up to the knowledge of authors, so far, only 76 cases of benign metastasizing leiomyoma have been reported.
  • The tumor presented as a retroperitoneal mass three years after a hysterectomy Performed for leiomyomatosis of the uterus with extensive areas of hyalinization.
  • Histopathologic and immunohistochemical studies of the resected mass were similar to the uterine leiomyoma, showing moderate cellularity of bland looking smooth muscle cells with minimal atypia, inconspicuous mitosis, and no necrosis in a hyalinized background.

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  • (PMID = 17198463.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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39. Bodner-Adler B, Bartl M, Wagner G: Intravenous leiomyomatosis of the uterus with pulmonary metastases or a case with benign metastasizing leiomyoma? Anticancer Res; 2009 Feb;29(2):495-6
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  • [Title] Intravenous leiomyomatosis of the uterus with pulmonary metastases or a case with benign metastasizing leiomyoma?
  • BACKGROUND: Intravenous leiomyomatosis (IVL) is defined as an intraluminal growth of benign smooth muscle cells in either venous or lymphatic vessels outside the confines or even in the absence of leiomyomas.
  • Benign metastasizing uterine leiomyoma is defined as a histologically benign uterine smooth muscle tumor that acts in a somewhat malignant fashion and produces benign metastases.
  • We report a case of a patient suffering from IVL of the uterus and pulmonary leiomyomatosis.
  • The patient was put on a regimen of gonadotropin-releasing hormone for a total of 6 months and a lung scan after 6 months revealed stable disease.
  • CONCLUSION: Though intravenous leiomyomatosis imitates a malignant neoplasm concerning the pattern of growth and extension, and benign metastasizing leiomyoma produces benign metastases, they must be differentiated histologically from malignant tumors to prevent overtreatment.


40. García-Reyna JC, Rico Martínez G, Vega González IF, Linares LM, Delgado Cedillo EA, Romero Ramírez R: [Musculoskeletal tumor evaluation with 99mTc-Tetrofosmin]. Acta Ortop Mex; 2008 Nov-Dec;22(6):390-6
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  • [Title] [Musculoskeletal tumor evaluation with 99mTc-Tetrofosmin].
  • [Transliterated title] 99mTc-Tetrofosmin en la evaluación de tumores musculoesqueléticos.
  • INTRODUCTION: (99m)Tc-tetrofosmin is an efficient agent as a tumor marker.
  • Nevertheless, benign pathology such as active inflammation is a source of false positives and the attending physician must consider the aid of complementary studies such as histopathology.
  • [MeSH-major] Bone Neoplasms / radionuclide imaging. Muscle Neoplasms / radionuclide imaging. Organophosphorus Compounds. Organotechnetium Compounds. Radiopharmaceuticals

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  • (PMID = 19280840.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Clinical Trial; Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / Organophosphorus Compounds; 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 0 / technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
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41. McCluggage WG, Boyde A: Uterine angioleiomyomas: a report of 3 cases of a distinctive benign leiomyoma variant. Int J Surg Pathol; 2007 Jul;15(3):262-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine angioleiomyomas: a report of 3 cases of a distinctive benign leiomyoma variant.
  • We report 3 cases of a distinctive uterine leiomyoma containing numerous thick-walled vascular channels, which we term angioleiomyoma.
  • They were composed of bland, spindle-shaped cells with numerous evenly distributed, arteriole-like vessels with thick muscular walls throughout.
  • The spindle cells were positive with smooth-muscle markers and negative with HMB45.
  • We believe angioleiomyoma should be recognized as a distinct entity and included in the World Health Organization classification of tumors of the female genital tract as a benign leiomyoma variant, similar to cellular and atypical leiomyoma.
  • Uterine angioleiomyoma has a close morphological resemblance to the similarly named skin tumor.
  • We review uterine smooth-muscle and other mesenchymal neoplasms in which prominent vascular channels are a feature.
  • [MeSH-minor] Actins / genetics. Actins / metabolism. Adult. Antigens, Neoplasm. Calmodulin-Binding Proteins / genetics. Calmodulin-Binding Proteins / metabolism. Desmin / genetics. Desmin / metabolism. Female. Gene Expression Regulation, Neoplastic. Humans. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / genetics. Neoplasm Proteins / metabolism

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  • (PMID = 17652533.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Calmodulin-Binding Proteins; 0 / Desmin; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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42. Gleason BC, Fletcher CD: Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol; 2008 Mar;32(3):354-62
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  • [Title] Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential.
  • Benign fibrous histiocytoma (FH) is one of the most common mesenchymal neoplasms of the skin.
  • Deep benign FH is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue.
  • Immunohistochemistry revealed expression of CD34 in 20/50 cases (40%), smooth muscle actin in 15/40 (38%), and focal desmin in 1/12 (8%).
  • Of the 37 patients for whom clinical follow-up was available (median, 40 mo), 8 (22%) had a local recurrence; in all 8 cases, the tumor had been marginally or incompletely excised.
  • Metastases occurred in 2 patients (5%), both of whom ultimately died of disease; however, this number is likely exaggerated due to consultation bias.
  • The metastasizing tumors were large (6 and 9 cm) and 1 had tumor necrosis but they were otherwise histologically identical to the nonmetastasizing lesions.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasm Metastasis / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD34 / analysis. Child. Desmin / analysis. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mitosis. Necrosis. Neoplasm Recurrence, Local

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  • (PMID = 18300816.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin
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43. Kefeli M, Yildiz L, Kaya FC, Aydin O, Kandemir B: Fascin expression in uterine smooth muscle tumors. Int J Gynecol Pathol; 2009 Jul;28(4):328-33
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  • [Title] Fascin expression in uterine smooth muscle tumors.
  • SUMMARY: The diagnosis of malignant, uncertain malignant potential, and benign uterine smooth muscle tumors is derived from histologic criteria such as tumor cell necrosis, mitotic activity, and cytologic atypia.
  • In this study, we compared fascin expression in cases of leiomyoma, leiomyoma variants (LVs), uterine smooth muscle tumor of uncertain malignant potential (STUMP), and LMS, and sought to determine the potential role of fascin in differential diagnosis.
  • Fascin expression was investigated through the immunohistochemistry of paraffin-embedded tissue in 79 cases of uterine smooth muscle tumor including 22 usual leiomyoma, 31 LV, 4 STUMP, and 22 LMS cases.
  • There was a statistically significant difference in fascin extent and intensity between the LMS and benign groups, but no difference between the LMS and STUMP groups.
  • The results of this study indicate that more distinct fascin expression exists in LMS than in the benign groups.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carrier Proteins / biosynthesis. Leiomyoma / pathology. Leiomyosarcoma / pathology. Microfilament Proteins / biosynthesis. Smooth Muscle Tumor / pathology. Uterine Neoplasms / pathology

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  • (PMID = 19483633.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carrier Proteins; 0 / Microfilament Proteins; 146808-54-0 / fascin
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44. Kucur M, Isman FK, Balci C, Onal B, Hacibekiroglu M, Ozkan F, Ozkan A: Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia. Urol Oncol; 2008 Jan-Feb;26(1):47-52
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  • [Title] Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
  • Although high levels of YKL-40 and chitotriosidase are associated with several diseases, the physiological functions of these enzymes are still unclear.
  • YKL-40, a growth factor for connective tissue cells, a migration factor for endothelial and vascular smooth muscle cells, is expressed by several types of solid human carcinoma, including prostate carcinoma.
  • PURPOSE: The purpose of this study was to compare serum YKL-40 levels and chitotriosidase activity both in benign prostatic hyperplasia and primary prostate cancer.
  • METHODS: YKL-40 and chitotriosidase were determined in serum samples from 93 patients with primary prostate cancer and 61 patients with benign prostatic hyperplasia.
  • CONCLUSION: High serum YKL-40 levels in patients with primary prostate cancer indicate that YKL-40 may have a function in the progression of malignant diseases, whereas no significant elevation was observed in benign prostatic hyperplasia.
  • Further studies are needed to elucidate the biologic role of YKL-40 in cancer aggressiveness and in progression of malignant diseases.
  • [MeSH-major] Biomarkers, Tumor / blood. Glycoproteins / blood. Hexosaminidases / blood. Prostatic Hyperplasia / diagnosis. Prostatic Neoplasms / diagnosis


45. Parker WH: Uterine myomas: management. Fertil Steril; 2007 Aug;88(2):255-71
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  • [Title] Uterine myomas: management.
  • OBJECTIVE: To review the currently available literature regarding the current management alternatives available to women with uterine myomas.
  • DESIGN: Literature review of 198 articles pertaining to uterine myomas.
  • RESULT(S): Many advances have been made in the management of uterine myomas.
  • CONCLUSION(S): Many options are now available to women with uterine myomas.
  • The presently available literature regarding the treatment of myomas is summarized.
  • [MeSH-major] Myoma / therapy. Uterine Neoplasms / therapy

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  • (PMID = 17658523.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 33515-09-2 / Gonadotropin-Releasing Hormone; 4G7DS2Q64Y / Progesterone
  • [Number-of-references] 141
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46. Missall TA, Burkemper NM, Jensen SL, Hurley MY: Immunohistochemical differentiation of four benign eccrine tumors. J Cutan Pathol; 2009 Feb;36(2):190-6
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  • [Title] Immunohistochemical differentiation of four benign eccrine tumors.
  • METHODS: Ten examples each of normal eccrine structures and of four benign eccrine tumors are analyzed with antibodies to cytokeratin (CK) 7, CD34, CK6, CK10, smooth muscle actin (SMA) and CD10.
  • This redundancy in staining is performed on four benign eccrine tumors to better interpret the existing literature.
  • [MeSH-major] Adenoma, Sweat Gland. Antigens, CD34 / biosynthesis. Biomarkers, Tumor / biosynthesis. Keratins / biosynthesis. Neprilysin / biosynthesis. Sweat Gland Neoplasms / metabolism

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  • (PMID = 18564284.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 68238-35-7 / Keratins; EC 3.4.24.11 / Neprilysin
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47. Arif S, Ganesan R, Spooner D: Intravascular leiomyomatosis and benign metastasizing leiomyoma: an unusual case. Int J Gynecol Cancer; 2006 May-Jun;16(3):1448-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intravascular leiomyomatosis and benign metastasizing leiomyoma: an unusual case.
  • Benign metastasizing leiomyoma (BML) and intravascular leiomyomatosis (IVL) are rare variants of uterine leiomyomas.
  • We report a case of a 42-year-old female presenting with a left L4 nerve root lesion, left paravesical lesion, left ovarian cyst, multiple pulmonary metastases, and an intracaval lesion.
  • The remaining tumor was treated with a gonadotrophin-releasing hormone agonist, resulting in significant reductions in tumor size.
  • Long-term follow-up is recommended, and familiarity with rare forms of benign smooth muscle uterine tumors is essential in avoiding misdiagnosis and overtreatment.

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  • (PMID = 16803546.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Awonuga AO, Shavell VI, Imudia AN, Rotas M, Diamond MP, Puscheck EE: Pathogenesis of benign metastasizing leiomyoma: a review. Obstet Gynecol Surv; 2010 Mar;65(3):189-95
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  • [Title] Pathogenesis of benign metastasizing leiomyoma: a review.
  • Uterine leiomyomas are benign tumors of smooth muscle origin with protean symptomatology, and are the most common gynecological tumor in women of reproductive age.
  • Very rarely, benign uterine leiomyomas display bizarre growth patterns with associated extrauterine benign-appearing smooth muscle tumors, similar to the smooth muscle cells found in a uterine fibroid, and are given the name benign metastasizing leiomyoma (BML).
  • We reviewed the published literature to outline the possible etiology of benign metastasizing leiomyoma (BML), and explored the similarities between BML and endometriosis.
  • It is hoped that analyses of the etiology and features of this disorder will facilitate a better understanding of its pathogenesis and treatment.
  • LEARNING OBJECTIVES: After completion of this article, the reader will be able to asses the clinical characteristics of Benign Metastasizing Leiomyoma.
  • Compare the potential pathophysiology with endometriosis and differentiate benign metastasizing Leiomyoma from Leiomyosarcoma.

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  • (PMID = 20214834.001).
  • [ISSN] 1533-9866
  • [Journal-full-title] Obstetrical & gynecological survey
  • [ISO-abbreviation] Obstet Gynecol Surv
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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49. Haasper C, Länger F, Rosenthal H, Knobloch K, Mössinger E, Krettek C, Bastian L: Coccydynia due to a benign notochordal cell tumor. Spine (Phila Pa 1976); 2007 Jun 15;32(14):E394-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coccydynia due to a benign notochordal cell tumor.
  • OBJECTIVE: To present a rare case of a notochordal cell tumor.
  • SUMMARY OF BACKGROUND DATA: We report on a 27-year-old female patient with pain at the lower back and muscle cramps in the area of the right hip.
  • RESULTS: Histology revealed an intraosseous benign notochordal cell tumor.
  • This tumor represents a recently described notochordal cell proliferation biologically distinct from chordomas.

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  • (PMID = 17572612.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Duhan N, Sirohiwal D: Uterine myomas revisited. Eur J Obstet Gynecol Reprod Biol; 2010 Oct;152(2):119-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine myomas revisited.
  • The present study was planned to review the pathophysiology of uterine myomas and emphasize the principles of logical management on the basis of literature review and synthesis of the author's experience.
  • The growth of uterine myomas, the most common solid pelvic tumors in women, is related to genetic predisposition, hormonal influences and growth factors.
  • Most asymptomatic myomas can be followed serially for progressive growth or development of symptoms.

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  • [Copyright] Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20933150.001).
  • [ISSN] 1872-7654
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
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51. Nappi L, Matteo M, Giardina S, Rosenberg P, Indraccolo U, Greco P: Management of uterine giant myoma. Arch Gynecol Obstet; 2008 Jul;278(1):61-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of uterine giant myoma.
  • BACKGROUND: Giant myomas of the uterus are uncommon, particularly in developed countries.
  • CASE: This report illustrates a case of a woman with a bilobated giant myoma of the uterus weighed in total 27.7 kg.
  • CONCLUSIONS: The knowledge of the different clinical manifestation of these myomas may allow to face that with adequate perioperative care, in order to assure a carefully and successfully surgery, although sometimes a benign pathology may be not easy to suspect in a first time.

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  • (PMID = 18066710.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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52. Bosev D, Dimitrov A: [Changes in uterine myoma dimentions during pregnancy]. Akush Ginekol (Sofiia); 2007;46(5):3-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Changes in uterine myoma dimentions during pregnancy].
  • The purpose of this study is to follow up the changes in the myoma dimentions during pregnancy (1st, 2nd and 3rd trimester).
  • The study is prospective and includes 90 pregnant women with myoma during the period 2002-2006.
  • If more than one myoma was diagnosed, the largest one was considered to be representative.
  • Our data show that the combination of myoma and pregnancy is more frequent with women over the age of 30 and it is more frequent with nullipares (63.2%).
  • Single myomas were more frequent with 58%, 48% of the myomas were intramural and 62% were located in the uterine corpus.
  • Our study shows that during the first trimester there is no change in the myomas dimentions in 35%-43% of the cases and during the second trimester there is no change of the myona dimentions in 50% of the cases.
  • During the third trimester there are only 5% of the myomas that change their dimentions.
  • We conclude, that the myomas, that enlarge during the first trimester, usually enlarge during the second trimester as well.
  • We found no decrease of the myoma dimentions during the third trimester.

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  • (PMID = 17974174.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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53. Simon RA, Sung CJ, Lawrence WD, Quddus MR: Vascular plexiform leiomyoma mimicking uterine tumor resembling ovarian sex cord tumor. Ann Diagn Pathol; 2010 Oct;14(5):355-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular plexiform leiomyoma mimicking uterine tumor resembling ovarian sex cord tumor.
  • Leiomyomata are common benign smooth muscle neoplasms with a usually easily recognizable histologic pattern.
  • However, there is a wide variety of subtypes described in the literature, characterized by predominance of a particular distinct histologic pattern.
  • Here we describe a case of a highly vascular leiomyoma with a prominent plexiform pattern and cords and tubules of epithelioid cells that mimics a uterine tumor resembling an ovarian sex cord tumor.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20850699.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Song SY, Noh JH, Lee SJ, Son HJ: Bronchogenic cyst of the stomach masquerading as benign stromal tumor. Pathol Int; 2005 Feb;55(2):87-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bronchogenic cyst of the stomach masquerading as benign stromal tumor.
  • Microscopically, the gastric subserosa showed cystic structures lined by pseudostratified ciliated columnar epithelium, seromucinous gland, connective tissue and complete layers of smooth muscle bundles.
  • [MeSH-major] Bronchogenic Cyst / pathology. Gastrointestinal Stromal Tumors / diagnosis. Stomach Diseases / pathology. Stomach Neoplasms / diagnosis

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  • (PMID = 15693855.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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55. Cohen DT, Oliva E, Hahn PF, Fuller AF Jr, Lee SI: Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation. AJR Am J Roentgenol; 2007 Jan;188(1):246-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation.
  • OBJECTIVE: This essay illustrates the salient features of variant smooth-muscle tumors on multiple imaging techniques with correlative pathology.
  • CONCLUSION: Parasitic leiomyoma, intravenous leiomyomatosis, disseminated peritoneal leiomyomatosis, and benign metastasizing leiomyoma show key features on multiple imaging techniques that correlate with pathology findings.
  • In the appropriate clinical setting, the radiologist should include these unusual lesions in the broader differential diagnosis of smooth-muscle tumors and, in certain cases, aid in surgical planning.
  • [MeSH-major] Diagnostic Imaging / methods. Image Enhancement / methods. Leiomyoma / diagnosis. Smooth Muscle Tumor / diagnosis. Uterine Neoplasms / diagnosis

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  • (PMID = 17179374.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 7
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56. Corapçioğlu F, Kargi A, Olgun N, Ozer E, Olguner M, Sarialioğlu F: Inflammatory myofibroblastic tumor of the ileocecal mesentery mimicking abdominal lymphoma in childhood: report of two cases. Surg Today; 2005;35(8):687-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inflammatory myofibroblastic tumor of the ileocecal mesentery mimicking abdominal lymphoma in childhood: report of two cases.
  • An inflammatory myofibroblastic tumor is an uncommon benign tumor located in various organs that can be misdiagnosed as a malignant neoplasm.
  • The histopathological diagnosis was inflammatory myofibroblastic tumor.
  • Inflammatory myofibroblastic tumor is a rare pseudosarcomatous clinical and pathological entity.
  • Although this tumor is more commonly reported in the lung, it can be detected in extrapulmonary sites, including the mesentery.
  • Because the choice of treatment for this tumor is conservative surgery, an accurate preoperative analysis is important to avoid any unnecessary aggressive surgical intervention or other therapeutic approaches.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Lymphoma / diagnosis. Neoplasms, Muscle Tissue / diagnosis. Peritoneal Neoplasms / diagnosis

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  • [Cites] Surg Today. 1998;28(11):1172-4 [9851627.001]
  • [Cites] J Pediatr Surg. 2001 Jun;36(6):908-12 [11381424.001]
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  • (PMID = 16034552.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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57. Gatalica Z, Hes O, Vanecek T, Sanger W: Renal smooth muscle hamartoma. Pathol Res Pract; 2010 Nov 15;206(11):782-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Renal smooth muscle hamartoma.
  • A large (4 cm in diameter) smooth muscle tumor was found in the medial aspect of the right kidney in a 54-year-old Caucasian woman with acute hypertension.
  • These findings are consistent with smooth muscle hamartoma, a rare benign renal tumor-like lesion.
  • [MeSH-major] Hamartoma / pathology. Kidney Diseases / pathology. Muscle, Smooth / pathology

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  • [Copyright] Copyright © 2010 Elsevier GmbH. All rights reserved.
  • (PMID = 20462705.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Receptors, Androgen; 9007-49-2 / DNA
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58. Xu YY, Luo XM, Zhou SH, Zheng ZJ: CD34-positive expression in benign nasal glomus tumour: two case reports and a literature review. J Int Med Res; 2010;38(6):2169-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD34-positive expression in benign nasal glomus tumour: two case reports and a literature review.
  • Nasal glomus tumours are extremely rare neoplasms with poorly understood histogenesis, but which are clinically recognized as benign.
  • CD34 is known to be a marker of tumour progenitor cells.
  • In this report, two cases of benign nasal glomus tumour are presented.
  • Tumour cells from both cases were positive for α-smooth muscle actin, actin, vimentin and CD34 protein.
  • [MeSH-major] Antigens, CD34 / metabolism. Glomus Tumor / metabolism. Nose Neoplasms / metabolism

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  • (PMID = 21227023.001).
  • [ISSN] 1473-2300
  • [Journal-full-title] The Journal of international medical research
  • [ISO-abbreviation] J. Int. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34
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59. Saadat P, Doostan A, Vadmal MS: Folliculosebaceous smooth muscle hamartoma. J Am Acad Dermatol; 2007 Jun;56(6):1021-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Folliculosebaceous smooth muscle hamartoma.
  • Cutaneous hamartomas are a group of heterogenous benign skin conditions demonstrating epithelial and mesenchymal components in varying proportions.
  • Folliculosebaceous (cystic) hamartomas comprise a distinct group of uncommon cutaneous tumor-like malformations.
  • We review the literature on folliculosebaceous hamartoma and report a case with smooth muscle as its only stromal component.
  • [MeSH-major] Hamartoma / pathology. Muscle, Smooth / pathology. Muscular Diseases / pathology

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  • (PMID = 17504719.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Klonisch T, Müller-Huesmann H, Riedel M, Kehlen A, Bialek J, Radestock Y, Holzhausen HJ, Steger K, Ludwig M, Weidner W, Hoang-Vu C, Hombach-Klonisch S: INSL3 in the benign hyperplastic and neoplastic human prostate gland. Int J Oncol; 2005 Aug;27(2):307-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] INSL3 in the benign hyperplastic and neoplastic human prostate gland.
  • In the present study we have investigated the expression of human INSL3 in patients with benign prostate hyperplasia (BPH), prostate intraepithelial neoplasia (PIN) and prostate carcinoma tissues.
  • Weaker INSL3 mRNA expression and immunoreactive INSL3 production were observed in secretory epithelial cells and in interstitial smooth muscle cells.
  • In addition to expressing INSL3 mRNA, the LGR8-negative DU-145 also expressed an INSL3 splice form formerly demonstrated in thyroid carcinoma cells.
  • Instead, PC-3 responded to INSL3 with significantly enhanced tumor cell motility and a transcriptional down-regulation of ErbB receptors and EGF.
  • [MeSH-major] Insulin / genetics. Prostatic Hyperplasia / pathology. Prostatic Intraepithelial Neoplasia / pathology. Prostatic Neoplasms / pathology. Proteins / genetics
  • [MeSH-minor] Cell Line, Tumor. Cell Movement / drug effects. Cell Proliferation / drug effects. Cell Survival / drug effects. Cyclic AMP / metabolism. Dose-Response Relationship, Drug. Epidermal Growth Factor / pharmacology. Epithelial Cells / drug effects. Epithelial Cells / metabolism. Gene Expression / drug effects. Humans. Immunohistochemistry. In Situ Hybridization. Male. RNA, Messenger / genetics. RNA, Messenger / metabolism. Receptors, G-Protein-Coupled / analysis. Receptors, G-Protein-Coupled / genetics. Recombinant Proteins / pharmacology. Reverse Transcriptase Polymerase Chain Reaction. Time Factors. Tretinoin / pharmacology


61. Clarke JT, Clarke LE, Miller C, Helm KF, Zaenglein AL: Plaque-like myofibroblastic tumor of infancy. Pediatr Dermatol; 2007 Sep-Oct;24(5):E83-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plaque-like myofibroblastic tumor of infancy.
  • We report an unusual spindle cell tumor occurring in two infants within the first 3 months of life.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasms, Muscle Tissue / pathology. Skin Neoplasms / pathology

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  • (PMID = 17958789.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Demirci F, Somunkiran A, Safak AA, Ozdemir I, Demirci E: Vaginal removal of prolapsed pedunculated submucosal myoma during pregnancy. Adv Ther; 2007 Jul-Aug;24(4):903-6
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vaginal removal of prolapsed pedunculated submucosal myoma during pregnancy.
  • Pedunculated submucosal myomas are generally associated with infertility and are most often encountered during the preconception period.
  • This report describes a 38-y-old pregnant woman in whom a pedunculated submucosal myoma resulted in preterm labor and was successfully removed vaginally at 26 wk gestation.

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  • (PMID = 17901039.001).
  • [ISSN] 0741-238X
  • [Journal-full-title] Advances in therapy
  • [ISO-abbreviation] Adv Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Atallah D, Checrallah A, Rouzier R, Ghossain MA, Chahine G: Retroperitoneal lymphangioleiomyoma mimicking ovarian tumor emerging after tamoxifen therapy. Obstet Gynecol; 2006 Sep;108(3 Pt 2):762-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retroperitoneal lymphangioleiomyoma mimicking ovarian tumor emerging after tamoxifen therapy.
  • Estrogen and progesterone receptors were positive on smooth muscle cells and human melanoma black 45 was negative.
  • We speculate that tamoxifen treatment may play a role in the development of this benign tumor.

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  • (PMID = 17018494.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 094ZI81Y45 / Tamoxifen
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64. Practice Committee of American Society for Reproductive Medicine in collaboration with Society of Reproductive Surgeons: Myomas and reproductive function. Fertil Steril; 2008 Nov;90(5 Suppl):S125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myomas and reproductive function.
  • The purpose of this Educational Bulletin is to examine the relationship between myomas and reproductive function and to review current methods for their management.
  • [MeSH-major] Myoma / physiopathology. Reproduction / physiology. Uterine Neoplasms / physiopathology

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  • (PMID = 19007608.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 33515-09-2 / Gonadotropin-Releasing Hormone
  • [Number-of-references] 72
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65. Huss WJ, Gray DR, Greenberg NM, Mohler JL, Smith GJ: Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Res; 2005 Aug 1;65(15):6640-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells.
  • Putative prostate stem cells and prostate tumor stem cells in benign and malignant human prostate tissue, in primary human prostate xenografts, and in the transgenic adenocarcinoma of the mouse prostate (TRAMP) mouse model of prostate cancer, are defined by expression of breast cancer resistance protein (BCRP), a marker of pluripotent hematopoietic, muscle, and neural stem cells, and by an absence of androgen receptor (AR) protein.
  • In both benign and malignant human prostate tissue, the rare epithelial cells that express BCRP and lack AR protein are localized in the basal cell compartment, survive androgen deprivation, and maintain proliferative potential in the hypoxic, androgen-deprived prostate.
  • Putative prostate tumor stem cells that express BCRP but not AR protein in TRAMP are the source of a BCRP-negative and AR-negative, Foxa2- and SV40Tag-expressing, transit amplifying compartment that progresses to the poorly differentiated carcinomas that arise rapidly after castration.
  • Therefore, BCRP expression isolates prostate stem/tumor stem cells from the prostate tissue microenvironment through constitutive efflux of androgen, protecting the putative tumor stem cells from androgen deprivation, hypoxia, or adjuvant chemotherapy, and providing the nidus for recurrent prostate cancer.

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  • (PMID = 16061644.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA84296; United States / NCI NIH HHS / CA / P01 CA077739; United States / NCI NIH HHS / CA / CA77739; United States / NCI NIH HHS / CA / CA64851; United States / NIEHS NIH HHS / ES / ES07017; United States / NCI NIH HHS / CA / CA64865
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABCG2 protein, human; 0 / Androgens; 0 / Indoles; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / Receptors, Androgen; 17EC19951N / Novobiocin; CW5S8OP3VO / tryptoquivaline
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66. Murtoniemi K, Pirinen E, Kähkönen M, Heiskanen N, Heinonen S: Smooth muscle tumor of the placenta - an entrapped maternal leiomyoma: a case report. J Med Case Rep; 2009;3:7302

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Smooth muscle tumor of the placenta - an entrapped maternal leiomyoma: a case report.
  • Tumors arising from the placental tissue include two distinct histological types: the benign vascular tumor, chorangioma, and very rarely, choriocarcinoma.
  • Benign leiomyomas, in contrast, are very common tumors of the uterine wall and occur in 0.1% to 12.5% of all pregnant women.
  • This case is possibly the first report on this kind of a placental tumor which has been examined using both immunohistochemistry and chromosome analysis.
  • CASE PRESENTATION: A 34-year-old G4P3 Caucasian woman was followed up antenatally because of a stillbirth in her previous pregnancy.
  • Histologically, the tumor was a benign leiomyoma and this finding was supported by immunohistochemistry.
  • Chromosomes of the neoplasm were studied by the fluorescence in situ hybridization technique and the tumor was found to carry XX chromosomes.
  • CONCLUSION: A rare benign smooth muscle neoplasm involving the placental parenchyma is presented.
  • The tumor was a uterine leiomyoma of maternal origin, which had become entrapped by the placenta.

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  • [Cites] Indian J Pathol Microbiol. 2005 Apr;48(2):223-4 [16758675.001]
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  • (PMID = 19830174.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2726536
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67. Al-Sindi K, Al-Shehabi MH, Al-Khalifa SA: Inflammatory myofibroblastic tumor of paranasal sinuses. Saudi Med J; 2007 Apr;28(4):623-7
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  • [Title] Inflammatory myofibroblastic tumor of paranasal sinuses.
  • Inflammatory myofibroblastic tumors IMTs are clinico-pathologically distinctive but biologically controversial entities; they rarely affect the head and neck region and usually follow a benign clinical course after radical excision.
  • Tumor cells were immunoreactive for vimentin, and smooth muscle actin, negative for desmin, S-100, p53, Cyclin D1, and bcl-2.
  • The lesion was excised completely by a CO2 LASER as a new treatment modality and the patient manifested no evidence of disease recurrence at 10-months recall.
  • [MeSH-major] Neoplasms, Muscle Tissue / surgery. Paranasal Sinus Neoplasms / surgery


68. Lee CH, Turbin DA, Sung YC, Espinosa I, Montgomery K, van de Rijn M, Gilks CB: A panel of antibodies to determine site of origin and malignancy in smooth muscle tumors. Mod Pathol; 2009 Dec;22(12):1519-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A panel of antibodies to determine site of origin and malignancy in smooth muscle tumors.
  • Leiomyosarcomas are malignant smooth muscle tumors that occur most commonly in the gynecologic tract and soft tissue.
  • There are different diagnostic criteria of malignancy for smooth muscle tumors arising at gynecologic and soft tissue sites and they may be managed differently but determining the primary site of a smooth muscle tumor can be difficult in some cases.
  • In addition, the distinction between malignant and benign gynecologic tract smooth muscle tumors on morphologic grounds can be challenging.
  • In addition, we examined whether immunostains for p16, p53 and Ki-67 could distinguish between malignant and benign gynecologic smooth muscle tumors.
  • Diffuse p16 and p53 immunopositivity and high Ki-67 proliferation index, singly or in combination, yielded an overall sensitivity of 92% and specificity of 98% for distinguishing between gynecologic leiomyosarcomas and leiomyomas and can be used as indicators of malignancy for gynecologic smooth muscle tumors.
  • Although ER positivity can be used to support the gynecologic origin of a leiomyosarcomas, nuclear WT1 immunostaining is of little use.
  • [MeSH-major] Immunohistochemistry. Leiomyoma / chemistry. Leiomyosarcoma / chemistry. Muscle Neoplasms / chemistry. Muscle, Smooth / chemistry. Uterine Neoplasms / chemistry. WT1 Proteins / analysis
  • [MeSH-minor] Adult. Antibodies. Biomarkers, Tumor / analysis. Canada. Cell Nucleus / chemistry. Cyclin-Dependent Kinase Inhibitor p16 / analysis. Diagnosis, Differential. Europe. Female. Humans. Kaplan-Meier Estimate. Ki-67 Antigen / analysis. Male. Middle Aged. Predictive Value of Tests. Receptors, Estrogen / analysis. Sensitivity and Specificity. Tissue Array Analysis. Tumor Suppressor Protein p53 / analysis. United States

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  • (PMID = 19734847.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA112270
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies; 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 0 / WT1 Proteins
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69. Hong R, Choi DY, Choi SJ, Lim SC: Multicentric infarcted leiomyoadenomatoid tumor: a case report. Int J Clin Exp Pathol; 2009;2(1):99-103

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric infarcted leiomyoadenomatoid tumor: a case report.
  • Adenomatoid tumor is a benign, usually small lesion that may be found within the wall of fallopian tubes or beneath the uterine serosa near the uterine cornu.
  • It is often accompanied by smooth muscle hypertrophy that may obscure the adenomatoid tumor.
  • We herein report a very unusual case of infarcted leiomyoadenomatoid tumor of the uterus and ovary in a 24-year-old woman who presented with severe lower abdominal pain and masses in the uterus and right ovary.
  • Laparoscopy-assisted transvaginal mass removal was performed under the clinical impression of a uterine leiomyoma and benign ovarian teratoma.
  • On a microscopic examination, prominent fascicles of smooth muscle separated or infiltrated by cuboidal or signet ring-like vacuolated cells, as well as tubular formations lined by flattened mesothelial cells and extensive necrosis were observed in both masses.
  • The microscopic appearance often suggested the possibility of a malignant neoplasm due to irregular pseudoinfiltration with atypical cuboidal cells and the paucity of a typical adenomatoid tumor due to infarction, and the presence of epithelial-appearing cells in the hypertrophic smooth muscle bundles that mimicked an infiltrating carcinoma for a leiomyoma or myometrium.

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  • [Cites] Int J Gynecol Pathol. 2007 Jan;26(1):16-20 [17197891.001]
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  • (PMID = 18830386.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Leiomyoadenomatoid tumor / infarction / ovary / uterus
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70. Yoon HJ, Kyung MS, Jung US, Choi JS: Laparoscopic myomectomy for large myomas. J Korean Med Sci; 2007 Aug;22(4):706-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic myomectomy for large myomas.
  • The aim of this study was to assess the feasibility and efficacy of laparoscopic myomectomy (LM) for large myomas.
  • A subpopulation of 51 patients with myomas 8 cm or larger in diameter was selected from 155 patients who underwent LM at Kangbuk Samsung Hospital from July 2003 to November 2006.
  • The mean operating time was 85.6 +/- 38.9 min, and the mean diameter of the largest myoma was 9.3 +/- 1.8 cm.
  • With the newly-developed screw and the port placement system that was modified from the Choi's 4-trocar method to obtain better surgical vision, LM of large myomas proved to be one of the efficient and feasible methods.

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  • [Cites] Surg Technol Int. 2006;15:123-9 [17029172.001]
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  • (PMID = 17728514.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2693824
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71. Kim TJ, Moon WK, Cha JH, Goo JM, Lee KH, Kim KH, Lee JW, Han JG, Weinmann HJ, Chang KH: VX2 carcinoma in rabbits after radiofrequency ablation: comparison of MR contrast agents for help in differentiating benign periablational enhancement from residual tumor. Radiology; 2005 Feb;234(2):423-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] VX2 carcinoma in rabbits after radiofrequency ablation: comparison of MR contrast agents for help in differentiating benign periablational enhancement from residual tumor.
  • PURPOSE: To prospectively compare the accuracy of a blood pool agent, SH L 643A, with that of gadopentetate dimeglumine in differentiating benign periablational enhancement from residual tumor in VX2 carcinomas in rabbits after radiofrequency (RF) ablation.
  • Sequential MR images were obtained before and with SH L 643A (17 000 Da, 0.05 mmol/kg) and, after a 24-hour interval, gadopentetate dimeglumine (546 Da, 0.1 mmol/kg) in 12 rabbits with VX2 carcinoma in the back muscle prior to (n = 12) and early (n = 12), 1 week (n = 8), and 4 weeks (n = 4) after RF ablation.
  • RF ablation was performed with output of 90 W but at less than 300 seconds to ensure incomplete tumor ablation.
  • The pathologic specimens were sectioned in the same plane as MR imaging, and the enhancement ratios (ie, the ratios of postcontrast to precontrast signal intensity) and the microvessel densities of residual tumor and benign periablational enhancement were assessed.
  • RESULTS: With SH L 643A, the peak enhancement ratios of residual tumor (1.64 +/- 0.31 [standard deviation]) were significantly higher than those of benign periablational enhancement (0.97 +/- 0.16) (P < .001).
  • With gadopentetate dimeglumine, the peak enhancement ratios of residual tumor (1.82 +/- 0.33) were not different from those of benign periablational enhancement (1.71 +/- 0.36).
  • In benign periablational enhancement, enhancement ratios with injection of SH L 643A were lower than those with injection of gadopentetate dimeglumine for all time points up to 30 minutes (P < .05).
  • The microvessel density was 25.72 +/- 5.43 vessels per field of view for residual tumor and 10.37 +/- 2.88 vessels per field of view for benign periablational enhancement (P < .001).
  • CONCLUSION: Blood pool contrast agent SH L 643A permits more accurate differentiation of benign periablational enhancement from residual tumor compared with the extracellular agent gadopentetate dimeglumine.
  • [MeSH-major] Catheter Ablation. Contrast Media. Gadolinium. Gadolinium DTPA. Magnetic Resonance Imaging. Neoplasm, Residual / diagnosis. Neoplasms, Experimental / surgery

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  • [Copyright] (c) RSNA, 2004.
  • [CommentIn] Radiology. 2005 Feb;234(2):317-8 [15670988.001]
  • [CommentIn] Radiology. 2005 Nov;237(2):745-7; author reply 748-9 [16244283.001]
  • [ErratumIn] Radiology. 2005 Nov;237(2):750
  • (PMID = 15591437.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / gadomer 17; AU0V1LM3JT / Gadolinium; K2I13DR72L / Gadolinium DTPA
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72. Gökaslan H, Türkeri L, Kavak ZN, Eren F, Sişmanoğlu A, Ilvan S, Durmuşoğlu F: Differential diagnosis of smooth muscle tumors utilizing p53, pTEN and Ki-67 expression with estrogen and progesterone receptors. Gynecol Obstet Invest; 2005;59(1):36-40
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  • [Title] Differential diagnosis of smooth muscle tumors utilizing p53, pTEN and Ki-67 expression with estrogen and progesterone receptors.
  • BACKGROUND/AIM: To investigate the expression and value for diagnosis of the genes, p53 and pTEN, the protein, Ki-67, and the receptors, estrogen and progesterone, in differentiating smooth muscle tumors of the uterus.
  • MATERIAL AND METHOD: Seventeen samples of leiomyosarcoma, 2 smooth muscle tumors with uncertain malignant potential (STUMP), 9 atypical myomas and 15 leiomyomas were stained immunohistochemically.
  • RESULTS: The malignant side of the spectrum was strongly stained for Ki-67 and p53 while uniformly decreasing toward the benign tumors.
  • The staining for progesterone receptor was also statistically significant, but the tumors that were considered benign, such as leiomyoma and atypical myoma, were the ones strongly stained (p = 0.005).
  • As the degree of differentiation of the tumor increased, the trend showed stronger staining for estrogen receptor.
  • CONCLUSION: The expression of Ki-67, p53 and progesterone receptors is promising in immunodifferentiation of smooth muscle tumors of the uterus with malignant potential.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Leiomyosarcoma / diagnosis. Smooth Muscle Tumor / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Immunohistochemistry / methods. Ki-67 Antigen / metabolism. PTEN Phosphohydrolase. Phosphoric Monoester Hydrolases / metabolism. Predictive Value of Tests. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Tumor Suppressor Protein p53 / metabolism. Tumor Suppressor Proteins / metabolism

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15377824.001).
  • [ISSN] 0378-7346
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; EC 3.1.3.- / Phosphoric Monoester Hydrolases; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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73. Ohtsuka T, Nomori H, Watanabe K, Naruke T: [Benign metastasizing leiomyoma of the lung. Report of a case]. Nihon Kokyuki Gakkai Zasshi; 2005 Feb;43(2):99-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign metastasizing leiomyoma of the lung. Report of a case].
  • Benign metastasizing leiomyoma (BML) is the term used to describe multiple benign pulmonary leiomyomatous lesions occurring in patients with a previous history of uterine leiomyoma.
  • Pathological examination revealed that the tumor composed of spindle-shaped smooth muscle cells and its characteristics were remarkably similar to those of the previously resected uterine leiomyoma.
  • Therefore, these lung tumors could be considered to be lung metastases from a uterine leiomyoma (benign metastasizing leiomyoma).

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  • (PMID = 15770941.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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74. Loubignac F, Bourtoul C, Chapel F: Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance. World J Surg Oncol; 2009;7:42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance.
  • BACKGROUND: Lipoma is by far the most common of all benign soft-tissue tumors which far outnumber malignant tumors.
  • Liposarcoma (LPS), which arises in the fatty tissue, is rather an uncommon soft-tissue tumor.
  • In two-third of the cases, this tumor occurs in the muscle while often demonstrating a misleading benign appearance as observed in the majority of soft-tissue sarcomas.
  • CASE PRESENTATION: We report the case of a 50-year-old man operated on for a fat tumor of the thigh initially diagnosed as lipoma but revealing to be a myxoid liposarcoma after histopathological examination.
  • The initial incomplete tumor excision required the need for a re-excision with adjuvant chemotherapy and complementary radiotherapy.
  • CONCLUSION: When any suspicious soft-tissue tumor is diagnosed, the combined information gathered from accurate preoperative radiographic planning and X-rays or surgical biopsy is of tremendous value for establishing the most appropriate therapeutic program, highly adapted to the histopathological findings.

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  • (PMID = 19386100.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2678127
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75. Takahashi Y, Shimizu S, Ishida T, Aita K, Toida S, Fukusato T, Mori S: Plexiform angiomyxoid myofibroblastic tumor of the stomach. Am J Surg Pathol; 2007 May;31(5):724-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plexiform angiomyxoid myofibroblastic tumor of the stomach.
  • We report 2 cases of plexiform angiomyxoid myofibroblastic tumor of the stomach, a tumor entity that has not been described previously.
  • The tumor in case 2 was incidentally found at laparoscopic cholecystectomy.
  • The tumor caused gastric perforation in case 1.
  • Bland spindle tumor cells were observed, and they were separated by abundant intercellular myxoid matrix.
  • Immunohistochemically, the tumor cells were positive for alpha-smooth muscle actin and muscle actin, and negative for KIT, CD34, and S-100 protein.
  • Electron microscopic findings were consistent with the myofibroblastic nature of the tumor cells.
  • Although clinical follow-up data were insufficient, the histologic appearances suggested the benign nature of the tumors.
  • However, the tumor in case 1 caused gastric perforation and necessitated an emergency operation.
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Cytoplasm / ultrastructure. Diagnosis, Differential. Disease-Free Survival. Gastrectomy. Humans. Immunohistochemistry. Male. Middle Aged. Treatment Outcome

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  • [CommentIn] Am J Surg Pathol. 2008 Dec;32(12):1910-2; author reply 1912-3 [18824895.001]
  • [CommentIn] Am J Surg Pathol. 2008 Dec;32(12):1910; author reply 1912-3 [18824897.001]
  • (PMID = 17460456.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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76. Zhen B, Shen Y, Zhang YM, Zhu CH, Liu ZL: [Analysis of the differences in the expression of HSP27 and c-kit between benign prostatic hyperplasia and prostatic cancer tissues]. Zhonghua Nan Ke Xue; 2006 May;12(5):416-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of the differences in the expression of HSP27 and c-kit between benign prostatic hyperplasia and prostatic cancer tissues].
  • OBJECTIVE: To examine the differences in the expression of HSP27 and c-kit between benign prostatic hyperplasia (BPH) and prostatic cancer (PCa) tissues and to analyse the relationship between their expression and BPH and PCa, especially the relationship with the occurrence, development, prognosis and treatment of PCa.
  • The staining for c-kit in BPH tissues was located in the cytoplasm of smooth muscle cells, and in PCa tissues was located in epithelial cells.
  • CONCLUSION: The expression level of HSP27 and c-kit was highly correlated with the process of the development from BPH to PCa, and also correlated with tumor grades and stages.
  • [MeSH-major] Heat-Shock Proteins / biosynthesis. Neoplasm Proteins / biosynthesis. Prostatic Hyperplasia / metabolism. Prostatic Neoplasms / metabolism. Proto-Oncogene Proteins c-kit / biosynthesis

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  • (PMID = 16755871.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / HSP27 Heat-Shock Proteins; 0 / HSPB1 protein, human; 0 / Heat-Shock Proteins; 0 / Neoplasm Proteins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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77. Sohn WI, Kim JH, Jung SN, Kwon H, Cho KJ: Intramuscular lipoma of the sternocleidomastoid muscle. J Craniofac Surg; 2010 Nov;21(6):1976-8

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  • [Title] Intramuscular lipoma of the sternocleidomastoid muscle.
  • Intramuscular lipoma is a rare benign mesenchymal tumor that infiltrates the skeletal muscle.
  • To our knowledge, only 4 cases of intramuscular lipoma in the sternocleidomastoid muscle have been reported in the literature.
  • The recurrence rate of intramuscular lipoma is high, and it shows the pattern of infiltration to tissues, and thus different from general lipomas, its resection should include adjacent normal muscular tissues.
  • In addition, although rare, concerning intramuscular lipoma that developed in the head and neck area, because important structures are present densely in a small space, it is important to establish a preoperative plan by determining the size and location of the tumor through preoperative clinical and radiologic tests.
  • We had a case of intramuscular lipoma in sternocleidomastoid muscle and resected the mass completely including a portion of attached muscles.
  • [MeSH-major] Lipoma / diagnosis. Muscle Neoplasms / diagnosis. Neck Muscles / pathology

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  • (PMID = 21119474.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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78. Kho KA, Nezhat C: Parasitic myomas. Obstet Gynecol; 2009 Sep;114(3):611-5
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  • [Title] Parasitic myomas.
  • OBJECTIVE: To report a large case series of parasitic myomas and to examine their causes, associations, and risk factors.
  • METHODS: Retrospective chart review was performed on 12 patients found to have parasitic myomas between August 2000 and April 2008.
  • The following data were systematically collected: surgery date; indications for surgery; number, dates, and types of prior surgeries; prior use of morcellation; and locations of parasitic myomas.
  • RESULTS: Laparoscopic evaluation confirmed the presence of intraperitoneal and retroperitoneal myomas distinct from the uterus in 12 patients.
  • Three patients had multiple parasitic myomas, all of whom had a history of laparoscopic myomectomy with morcellation.
  • The majority (14 of 15) of myomas were found in the pelvis, including two retroperitoneal myomas, one of which was embedded in the bladder.
  • Six of 15 myomas were found along the gastrointestinal tract, and 1 of 15 was found in the upper abdomen.
  • CONCLUSION: Parasitic myomas may occur spontaneously as pedunculated subserosal myomas lose their uterine blood supply and parasitize to other organs.
  • More parasitic myomas may be iatrogenically created after surgery, particularly surgery using morcellation techniques.
  • With increasing rates of laparoscopic procedures, surgeons should be aware of the potential for iatrogenic parasitic myoma formation, their likely increasing frequency, and intraoperative precautions to minimize occurrence.

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  • (PMID = 19701042.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Hoetzenecker K, Ankersmit HJ, Aigner C, Lichtenauer M, Kreuzer S, Hacker S, Hoetzenecker W, Lang G, Klepetko W: Consequences of a wait-and-see strategy for benign metastasizing leiomyomatosis of the lung. Ann Thorac Surg; 2009 Feb;87(2):613-4
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  • [Title] Consequences of a wait-and-see strategy for benign metastasizing leiomyomatosis of the lung.
  • Pulmonary benign metastasizing leiomyomatosis (BML) is a rare smooth-muscle cell disorder of the lung.
  • Most BML lesions stay constant in size for a long time.
  • We conclude that a wait-and-see procedure for BML is feasible, but primary resection of the BML tumor masses is preferable to avoid complications as described in our case.

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  • (PMID = 19161793.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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80. Zustin J, Akpalo H, Gambarotti M, Priemel M, Rueger JM, Luebke AM, Reske D, Lange C, Pueschel K, Lohmann C, Rüther W, Amling M, Alberghini M: Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study. Am J Pathol; 2010 Sep;177(3):1072-8
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  • [Title] Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.
  • Chondromyxoid fibroma represents a rare benign cartilaginous tumor of young patients occurring in a subcortical metaphyseal location.
  • Archival paraffin-embedded tissues from 4 fetal femora and 10 cases of chondromyxoid fibroma were analyzed simultaneously using histochemistry (safranin O) and established immunohistochemical antibodies (CD34, CD163, and smooth muscle actin).
  • Based on the observed substantial morphological similarity between the cartilage canals and chondromyxoid fibroma, we suggest that the chondromyxoid fibroma represents a neoplasm originating from or mimicking the fetal cartilage canals within the immature cartilage.

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  • [Cites] Am J Clin Pathol. 2001 Aug;116(2):271-7 [11488075.001]
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  • (PMID = 20671262.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2928941
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81. Kanaoka Y, Yoshida C, Tsukioka M, Noriyuki M, Ishiko O: Ratio of directly necrotized volume to total volume of a submucosal myoma predicts shrinkage after microwave endometrial ablation. J Obstet Gynaecol Res; 2009 Aug;35(4):717-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ratio of directly necrotized volume to total volume of a submucosal myoma predicts shrinkage after microwave endometrial ablation.
  • AIM: To explore parameters relating to shrinkage of submucosal myomas after microwave endometrial ablation.
  • METHODS: Fourteen patients underwent microwave endometrial ablation at 2.45 GHz using a curved microwave applicator to treat menorrhagia caused by a submucosal myoma.
  • The size of myomas was measured on magnetic resonance images before, one month after, and six months after the operation.
  • The average radius r was defined as half of the size of the myoma measured in three dimensions.
  • The protrusion ratio alpha was defined as the ratio of the thickness of the protruding part of a myoma in the uterine cavity to the size of the myoma before the operation.
  • The ratio of the directly necrotized volume by microwave irradiation to the total volume (RODNeV) of preoperative myomas was calculated using the following formula:.
  • (1) where d is the depth of myoma tissue directly necrotized by microwave irradiation.
  • RESULTS: Two-dimensional plots showing shrinkage of submucosal myomas versus the RODNeV indicated that shrinkage at six months after microwave endometrial ablation depends on the RODNeV.
  • Myomas with a RODNeV greater than 0.17 had shrunk more than 50% at six months after the operation.
  • CONCLUSIONS: RODNeV is closely related to postoperative necrosis and shrinkage of the submucosal myoma after microwave endometrial ablation.
  • Prediction of the shrinkage rate of submucous myomas appears to be possible by calculating the RODNeV preoperatively.

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  • (PMID = 19751333.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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82. Fernandes BF, Castiglione E, Belfort RN, Codère F, Burnier MN Jr: Orbital leiomyoma: histopathologic and immunohistochemical findings of a rare tumor. Ophthal Plast Reconstr Surg; 2009 Jan-Feb;25(1):59-61

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  • [Title] Orbital leiomyoma: histopathologic and immunohistochemical findings of a rare tumor.
  • A 51-year-old man was referred for evaluation of a right orbital hemangioma.
  • The tumor did not compromise other orbital structures.
  • Orbital leiomyoma is a slow-growing tumor that can be located anywhere in the orbit.
  • Posterior tumors are believed to originate from smooth muscle cells of vessel walls; anterior lesions may arise from the capsulopalpebral or Müller muscle.
  • Although there are no unique features that help the radiologist to exclude other benign lesions of the orbit, the histopathologic diagnosis using immunohistochemical markers is usually straightforward.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunoenzyme Techniques. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19273932.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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83. Cramer SF, Mann L, Calianese E, Daley J, Williamson K: Association of seedling myomas with myometrial hyperplasia. Hum Pathol; 2009 Feb;40(2):218-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of seedling myomas with myometrial hyperplasia.
  • Myometrial hyperplasia (MMH) is a common structural variation characterized by irregular zones of increased myometrial cellularity, with increased nucleus-cell ratios; but to date, there has been only anecdotal evidence that it may give rise to myomas.
  • We studied the relationship of seedling myomas to MMH in 50 consecutive hysterectomies and found that most seedling myomas (44/63, 70%) arose in MMH--35 in inframucosal MMH, 3 in subserosal MMH, and 6 from intramural MMH.
  • Some seedling myomas were incompletely circumscribed, seeming to arise not only in but also from MMH.
  • We suggest that even seedlings in normal myometrium may arise not from normal myometrial smooth muscle cells but rather from myometaplasia in intramural stromal emboli, with hyperplastic and then neoplastic transformation.

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  • (PMID = 18799191.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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84. Kusumi T, Minakawa M, Fukui K, Saito S, Ohashi M, Sato F, Fukuda I, Kijima H: Cardiac tumor comprising two components including typical myxoma and atypical hypercellularity suggesting a malignant change. Cardiovasc Pathol; 2009 Nov-Dec;18(6):369-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tumor comprising two components including typical myxoma and atypical hypercellularity suggesting a malignant change.
  • BACKGROUND: Cardiac myxoma is a benign neoplasm and is not considered to carry a risk of malignant transformation.
  • We describe a case of a cardiac tumor comprising typical myxoma and atypical cellular parts.
  • METHODS AND RESULTS: A 72-year-old woman was found to have a tumor in the left atrial chamber after undergoing echocardiographic investigation and so she underwent tumor excision surgery.
  • The excised tumor was composed of two components with different features with a smooth transition from one type to the other.
  • The apex of the tumor showed a gelatinous and villous appearance on gross examination, and histological examination revealed that the tumor cells had small oval nuclei and eosinophilic cytoplasm and were arranged in cords and vasoformative structures in the myxoid matrix.
  • The base of the tumor appeared as a solid mass on gross examination with hypercellular proliferation of spindle-shaped tumor cells and intersecting fascicles observed histologically.
  • On immunohistochemistry, the tumor cells were found to be positive for alpha-smooth muscle actin, calretinin, and CD34, and this immunoreactivity was decreased at the tip.
  • CONCLUSIONS: We diagnosed this tumor as cardiac myxoma with an atypical hypercellular component suggesting a malignant change.

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  • (PMID = 18619858.001).
  • [ISSN] 1879-1336
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Yang YP, Zhu YL, Wu WP, Wang ZM, Zhang JM: [Perivascular epithelioid cell tumor of uterus: report of 5 cases and literature review]. Zhonghua Bing Li Xue Za Zhi; 2007 May;36(5):302-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perivascular epithelioid cell tumor of uterus: report of 5 cases and literature review].
  • OBJECTIVE: To study the pathologic features, diagnosis, differential diagnosis and biologic behavior of uterine perivascular epithelioid tumor.
  • METHODS: Five cases of uterine perivascular epithelioid cell tumor were studied by light microscopy and immunohistochemistry.
  • Immunohistochemically, the tumor cells demonstrated positive staining for melanocytic markers (HMB45 and/or Melan-A), desmin and smooth muscle actin.
  • All the patients followed for a certain period are still alive, with no evidence of disease recurrence.
  • CONCLUSIONS: Perivascular epithelioid cell tumor is a rare mesenchymal tumor of uterus, with distinctive histologic and immunohistochemical features.
  • Positivity for melanocytic markers (especially HMB45) plays an important role in the diagnosis of this tumor.
  • In general, the tumor is categorized as benign, with uncertain malignant potential and malignant.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Neoplasm Proteins / metabolism. Perivascular Epithelioid Cell Neoplasms / pathology. Uterine Neoplasms / pathology

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  • (PMID = 17706136.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Desmin; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 24
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86. Pacchioni D, Volante M, Casetta G, Sapino A, Marchiò C, Bussolati G: Myxoid renal tumor with myoepithelial differentiation mimicking a salivary gland pleomorphic adenoma: description of a case. Am J Surg Pathol; 2007 Apr;31(4):632-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoid renal tumor with myoepithelial differentiation mimicking a salivary gland pleomorphic adenoma: description of a case.
  • We herein report an unusual case of a low-grade myxoid renal epithelial neoplasm, with peculiar and previously unreported morphologic and immunohistochemical features.
  • The immunohistochemical profile interestingly confirmed the myoepithelial differentiation of the basal epithelial layer, as demonstrated by the coexpression of several myoepithelial markers such as p63, caldesmon, calponin, smooth muscle actin, and S-100, together with epithelial markers such as low and high-molecular weight cytokeratins.
  • The tumor proved benign at follow-up.
  • A definitive classification and histogenetic interpretation of this previously unreported tumor type awaits description of further cases showing similar features which, perhaps, as it may happen, went so far unnoticed.
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Salivary Gland Neoplasms / pathology

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  • (PMID = 17414112.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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87. Lee HW, Lee JJ, Yang DH, Lee BH: A clinicopathologic study of glomus tumor of the stomach. J Clin Gastroenterol; 2006 Sep;40(8):717-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A clinicopathologic study of glomus tumor of the stomach.
  • Glomus tumors are benign lesions and originate from modified smooth muscle cells of the glomus body.
  • Here we report a case of a 67-year-old patient in whom glomus tumor of the stomach was diagnosed after 10-day history of melena.
  • We have reviewed the 13 cases selected from literature of gastric glomus tumor in Korean, including our case.
  • The tumor sizes varied from 1.2 to 3.8 cm (median 2.5 cm), and all tumors presented in antrum of stomach.
  • Although gastric glomus tumors can be considered more likely benign, a small possibility of malignant behavior cannot be ruled out.
  • [MeSH-major] Glomus Tumor. Stomach Neoplasms

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  • (PMID = 16940885.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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88. Agaimy A, Wünsch PH, Hofstädter F, Schroeder J: Hyaline globules in paucicellular leiomyomas of the gastrointestinal tract are distinct from skeinoid fibers and represent degenerating smooth muscle cells. Pathol Res Pract; 2009;205(6):417-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyaline globules in paucicellular leiomyomas of the gastrointestinal tract are distinct from skeinoid fibers and represent degenerating smooth muscle cells.
  • We investigated a total of 93 histologically and immunohistochemically well-characterized true smooth muscle neoplasms of the GI tract for the presence of hyaline globules.
  • A variable number of PAS-positive intracellular and interstitial hyaline globules were detected in all benign paucicellular leiomyomas of the muscularis mucosae (n=72) and the muscularis propria (n=14) irrespective of tumor size and site, but in none of leiomyosarcomas (n=7) and cellular leiomyoma (n=1).
  • Similar to surrounding tumor cells, hyaline globules expressed desmin, alpha-SMA, and h-caldesmon, but were negative for CD117 and CD34.
  • The above findings are consistent with a multistep degenerative phenomenon affecting individual smooth muscle cells in paucicellular GI leiomyomas.
  • Awareness of this finding would prevent misinterpretation as GIST, particularly in small biopsies.
  • [MeSH-major] Gastrointestinal Neoplasms / ultrastructure. Leiomyoma / ultrastructure. Myocytes, Smooth Muscle / ultrastructure

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  • (PMID = 19216034.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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89. Miller CE: Unmet therapeutic needs for uterine myomas. J Minim Invasive Gynecol; 2009 Jan-Feb;16(1):11-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unmet therapeutic needs for uterine myomas.
  • Uterine myomas may develop in many women, but only become clinically significant in about one third of the affected population.
  • Although uterine myomas are most often benign, they are associated with debilitating symptoms and commonly result in hysterectomy.
  • Current treatments for uterine myomas include pharmacologic therapies, delivery of focused energy, alteration of uterine vascular supply, or surgical procedures.
  • Factors such as the woman's desire for future pregnancy, the importance of uterine preservation, symptom severity, and tumor characteristics direct the choice of therapeutic approach.
  • The ideal treatment will have the following characteristics: easy to perform, minimally invasive, cost effective, preserves fertility, preserves the uterus, efficacious, acceptable tolerability and durability, and low incidence of myoma recurrence.

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  • (PMID = 19110181.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 110
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90. Rammeh-Rommani S, Mokni M, Stita W, Trabelsi A, Hamissa S, Sriha B, Tahar-Yacoubi M, Korbi S: [Uterine smooth muscle tumors: retrospective epidemiological and pathological study of 2760 cases]. J Gynecol Obstet Biol Reprod (Paris); 2005 Oct;34(6):568-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Uterine smooth muscle tumors: retrospective epidemiological and pathological study of 2760 cases].
  • [Transliterated title] Les tumeurs musculaires lisses de l'utérus: étude épidémiologique et anatomo-pathologique rétrospective de 2760 cas.
  • INTRODUCTION: Smooth muscle tumors of the uterus are frequent.
  • Most of them are benign.
  • Some leiomyomas may have unusual morphologic features difficult to distinguish from leiomyosarcoma.
  • OBJECTIVES: The purpose of our work is to study cases of leiomyosarcomas, cellular leiomyoma, atypical leiomyoma and mitotically active leiomyoma among a large series of uterine smooth muscle tumors.
  • MATERIALS AND METHODS: We reviewed retrospectively 2760 uterine smooth muscle tumors.
  • The slides were reviewed and the tumors reclassified according to the criteria of the WHO 2003 classification.
  • RESULTS: Review of the slides demonstrated: 12 mitotically active leiomyomas, 18 cellular leiomyomas, 20 atypical leiomyomas, 16 leiomysarcomas, only one case of smooth muscle tumor of uncertain malignant potential.
  • [MeSH-minor] Female. Humans. Leiomyoma / epidemiology. Leiomyoma / pathology. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 16208199.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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91. Ruiz E, Pozo P, Toselli L, Fernández M, Christiansen S, Lambertini R: Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma. Urology; 2008 Jun;71(6):1067-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma.
  • Paratesticular tumors are extremely rare, with paratesticular rhabdomyosarcoma being the most common finding.
  • A 6-month-old boy presented with an asymptomatic, right intrascrotal mass whereby the testicle was surrounded by a friable lipomatous tumor.
  • Histopathologic findings showed a juvenile xanthogranuloma, a non-Langerhans histiocytosis commonly described in infants in the skin and skeletal muscle.
  • [MeSH-major] Rhabdomyosarcoma / pathology. Testicular Diseases / pathology. Testicular Neoplasms / pathology. Xanthogranuloma, Juvenile / pathology

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  • (PMID = 18538690.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Kourda J, Ismail O, Smati BH, Ayadi A, Kilani T, El Mezni F: Benign myoepithelioma of the lung - a case report and review of the literature. Cases J; 2010;3(1):25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign myoepithelioma of the lung - a case report and review of the literature.
  • INTRODUCTION: Benign myoepithelioma is extremely rare in the lung, to the best of our knowledge; only five cases have been reported in the literature.
  • Histologically, there was a proliferation of small cells of a plasmocytoid-type, with a predominantly whorled pattern.
  • No mitotic activity or necrosis was seen in the tumor.
  • Immuhistochemically, the tumor cells positive for smooth muscle actin, vimentine, and S100 protein.
  • The diagnosis of benign myoepithelioma of the lung is so confirmed.
  • CONCLUSION: Benign myoepithelioma is a rare pulmonary neoplasm distinct from pleomorphic adenoma, which should be considered in the differential diagnosis of lung nodules.

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  • (PMID = 20180958.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2828429
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93. Koch P, Petri M, Paradowska A, Stenzinger A, Sturm K, Steger K, Wimmer M: PTPIP51 mRNA and protein expression in tissue microarrays and promoter methylation of benign prostate hyperplasia and prostate carcinoma. Prostate; 2009 Dec 1;69(16):1751-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PTPIP51 mRNA and protein expression in tissue microarrays and promoter methylation of benign prostate hyperplasia and prostate carcinoma.
  • In this study the expression of PTPIP51 and its in vitro interaction partners was investigated in human benign prostate hyperplasia (BPH) and in prostate carcinoma (PCa).
  • RESULTS: PTPIP51 mRNA and protein expression was detected in prostatic epithelia of BPH and in tumor cells of PCa, respectively, and within smooth muscle cells of the stromal compartment.
  • A stronger expression was present in nerve fibers, particularly in PCa, in immune cells and in smooth muscle and endothelial cells of vessels of BPH and PCa.
  • [MeSH-minor] Aged. CpG Islands / genetics. Endothelial Cells / metabolism. Epithelium / metabolism. Humans. Immune System / metabolism. Immune System / pathology. Male. Microarray Analysis. Middle Aged. Muscle, Smooth, Vascular / metabolism. Muscle, Smooth, Vascular / pathology. Myocytes, Smooth Muscle / metabolism. Neoplasm Invasiveness. Nerve Fibers / metabolism. Prostate / blood supply. Prostate / innervation. Prostate / metabolism. Tissue Distribution

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  • [Copyright] Copyright 2009 Wiley-Liss, Inc.
  • (PMID = 19691131.001).
  • [ISSN] 1097-0045
  • [Journal-full-title] The Prostate
  • [ISO-abbreviation] Prostate
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mitochondrial Proteins; 0 / RNA, Messenger; EC 3.1.3.48 / FAM82A2 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatases
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94. Vaquero ME, Magrina JF, Leslie KO: Uterine smooth-muscle tumors with unusual growth patterns. J Minim Invasive Gynecol; 2009 May-Jun;16(3):263-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine smooth-muscle tumors with unusual growth patterns.
  • Uterine smooth-muscle tumors with unusual growth patterns include a variety of neoplastic lesions characterized histologically by their similarity to adult smooth muscle tissue.
  • The 3 primary neoplasms are intravenous leiomyomatosis, benign metastasizing leiomyoma, and leiomyomatosis peritonealis disseminata.
  • [MeSH-major] Leiomyomatosis / pathology. Smooth Muscle Tumor / pathology. Uterine Neoplasms / pathology

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  • (PMID = 19423058.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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95. Tchartchian G, Dietzel J, Bojahr B, Hackethal A, De Wilde RL: No more abdominal hysterectomy for myomata using a new minimally-invasive technique. Int J Surg Case Rep; 2010;1(1):7-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] No more abdominal hysterectomy for myomata using a new minimally-invasive technique.
  • For a uterine weight of >1000 g, after a caesarean section and in nullipara per vaginam, the most common surgical technique for hysterectomy in patients is hysterectomy per laparotomiam.

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  • (PMID = 22096663.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC3199612
  • [Keywords] NOTNLM ; Hysterectomy / Laparoscopy / Laparotomy / Uterus myomatosus
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96. Dilek S, Ertunc D, Tok EC, Cimen R, Doruk A: The effect of myomectomy on health-related quality of life of women with myoma uteri. J Obstet Gynaecol Res; 2010 Apr;36(2):364-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The effect of myomectomy on health-related quality of life of women with myoma uteri.
  • Many studies have evaluated the effect of other methods rather than myomectomy on HRQoL, and have focused solely on the presence of myoma without regarding any concurrent pelvic pathology.
  • METHODS: This study involved 80 patients with myomas and 75 controls.
  • Domains of the Short Form - 36 (SF-36) questionnaire were evaluated pre- and postoperatively in 72 women with myomas.
  • Furthermore, any correlations between myoma characteristics and SF-36 physical components (PC) and mental components (MC) were investigated.
  • RESULTS: All SF-36 domains were lower in women with myoma uteri than in the control group, except for physical and social function.
  • There was no correlation between PC and MC scores and the number, location and total volume of the myomas.
  • However, fundal and posteriorly positioned myomas were related with the PC score, and posterior myomas with the MC score.
  • CONCLUSION: The findings from this study suggest that myomectomy improves HRQoL, and that myoma characteristics may modulate quality of life domains.

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  • (PMID = 20492389.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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97. Srivastava S, Roy R, Singh S, Kumar P, Dalela D, Sankhwar SN, Goel A, Sonkar AA: Taurine - a possible fingerprint biomarker in non-muscle invasive bladder cancer: A pilot study by 1H NMR spectroscopy. Cancer Biomark; 2010;6(1):11-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Taurine - a possible fingerprint biomarker in non-muscle invasive bladder cancer: A pilot study by 1H NMR spectroscopy.
  • It opens avenues for investigative research for the identification of new disease markers and diagnostic techniques.
  • In this pilot study, utility of non-invasive (1)H NMR spectroscopy has been evaluated for probing the metabolic perturbations occurring in non-muscle invasive urinary bladder cancer. (1)H NMR spectra of urine of bladder cancer patients and controls (healthy and urinary tract infection/bladder stone) (n = 103) were acquired at 400MHz.
  • The cancer patients showed significant (p < 0.05) variations in concentration of hippurate and citrate as compared with healthy controls and benign controls.
  • [MeSH-major] Biomarkers, Tumor / urine. Early Detection of Cancer / methods. Magnetic Resonance Spectroscopy / methods. Taurine / urine. Urinary Bladder Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Carcinoma in Situ / diagnosis. Carcinoma in Situ / metabolism. Humans. Male. Middle Aged. Neoplasm Staging. Pilot Projects. Protons. Sensitivity and Specificity. Young Adult

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  • Hazardous Substances Data Bank. Taurine .
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  • (PMID = 20164538.001).
  • [ISSN] 1875-8592
  • [Journal-full-title] Cancer biomarkers : section A of Disease markers
  • [ISO-abbreviation] Cancer Biomark
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Protons; 1EQV5MLY3D / Taurine
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98. Hald K, Kløw NE, Qvigstad E, Istre O: Treatment of uterine myomas with transvaginal uterine artery occlusion: possibilities and limitations. J Minim Invasive Gynecol; 2008 Sep-Oct;15(5):631-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of uterine myomas with transvaginal uterine artery occlusion: possibilities and limitations.
  • The objective of this pilot study was to evaluate the feasibility of a transvaginal clamp prototype used for temporary uterine artery occlusion as a treatment for myomas.
  • Ten premenopausal women aged 34 to 37 years with menorrhagia and myomas were treated with a temporary uterine artery occlusion for 6 hours.
  • Difficulties with application of the vaginal clamp were related to initial learning and size of the myomas.
  • Our initial experience shows that the treatment is feasible in some patients with symptomatic myomas.

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  • (PMID = 18722975.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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99. Sakamoto A, Yoshida T, Matsuura S, Tanaka K, Matsuda S, Oda Y, Hori Y, Yokomizo A, Iwamoto Y: Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features. World J Surg Oncol; 2007;5:88
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features.
  • BACKGROUND: The skeletal muscle is an unusual site for metastasis from renal cell carcinoma (RCC).
  • Metastatic RCC must be differentiated from benign primary soft-tissue tumors because aggressive surgical resection is necessary.
  • CASE PRESENTATION: We present the case of a 65-year-old man with metastatic RCC in the gluteus maximus muscle (3.8 cm in diameter) found on enhanced computed tomography (CT) 6 years after nephrectomy.
  • Because the growth of the lesion was slow, benign tumor was a differential diagnosis.
  • However, magnetic resonance imaging (MRI) showed that the mass had high-signal intensity on T1- and T2-weighted images (WIs) compared to that of skeletal muscle, with mild enhancement by Gadolinium.
  • Therefore, under a diagnosis of metastatic RCC, the lesion was resected together with the surrounding skeletal muscle.
  • CONCLUSION: MRI features of metastatic RCC may be beneficial in differentiating it from primary soft-tissue tumor.

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  • (PMID = 17683570.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1976113
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100. Chiang ER, Chen TH: Multiple glomus tumors in gastrocnemius muscle: a case report. Arch Orthop Trauma Surg; 2008 Jan;128(1):29-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple glomus tumors in gastrocnemius muscle: a case report.
  • Glomus tumors are rare benign tumors that account 1-5% of soft tissue tumors of the hand.
  • We describe an unusual case of recurrent glomus tumor located in lower leg.
  • [MeSH-major] Glomus Tumor / diagnosis. Muscle Neoplasms / diagnosis. Muscle, Skeletal. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17624538.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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