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1. Siepmann K, Wannke B, Neumann D, Rohrbach JM: Subcutaneous tumor of the lower eyelid: a potential manifestation of a Dirofilaria repens infection. Eur J Ophthalmol; 2005 Jan-Feb;15(1):129-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous tumor of the lower eyelid: a potential manifestation of a Dirofilaria repens infection.
  • PURPOSE: To report a case of Dirofilaria repens presenting as a subcutaneous tumor of the lower eyelid.
  • RESULTS: A 29-year-old man of Greek origin without systemic symptoms presented with a 3-week history of a small painless mass localized in the medial part of the lower eyelid.
  • There was no history of a preceding trauma, injury, or visual impairment; however, the patient had recently been on a holiday in Italy.
  • Upon surgical intervention a yellowish, pea-sized cyst-like structure was found beneath the orbicularis muscle and removed in toto.
  • Histologic examination revealed the presence of a wormlike structure with the characteristic features of a single adult Dirofilaria repens nematode.
  • CONCLUSIONS: Infection with the nematode Dirofilaria repens has to be considered in the differential diagnosis of malignant and benign tumors of subcutaneous periocular tissues in patients who traveled to endemic areas.
  • [MeSH-major] Dirofilaria / isolation & purification. Dirofilariasis / diagnosis. Eye Infections, Parasitic / diagnosis. Eyelid Diseases / diagnosis. Eyelid Neoplasms / diagnosis. Skin Diseases, Parasitic / diagnosis

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  • (PMID = 15751252.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Sachanandani NS, Brown JM, Zaidman C, Brown SS, Mackinnon SE: Intraneural perineurioma of the median nerve: case report and literature review. Hand (N Y); 2010 Sep;5(3):286-93
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  • Intraneural perineurioma is a benign peripheral nerve sheath tumor of perineurial cell origin.

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  • (PMID = 19876692.001).
  • [ISSN] 1558-9455
  • [Journal-full-title] Hand (New York, N.Y.)
  • [ISO-abbreviation] Hand (N Y)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2920385
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3. Hungermann D, Buerger H, Oehlschlegel C, Herbst H, Boecker W: Adenomyoepithelial tumours and myoepithelial carcinomas of the breast--a spectrum of monophasic and biphasic tumours dominated by immature myoepithelial cells. BMC Cancer; 2005;5:92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Current classification schemes are based on purely descriptive features and an assessment of individual prognosis is still problematic.
  • METHODS: A series of 27 adenomyoepithelial tumours of the breast was analysed immunohistochemically with antibodies directed against various cytokeratins, p63, smooth muscle alpha-actin (SMA) and vimentin.
  • Double immunofluorescence revealed tumour cells exclusively staining for Ck5/Ck14 in the presence of other cell populations that co-expressed high molecular weight Ck5/Ck14 as well as either low molecular weight Ck8/18 or SMA.
  • Based on morphology, we assigned the series to three categories, benign, borderline and malignant.
  • This classification was supported by a stepwise increase in cytogenetic alterations on CGH.
  • Although categorisation of adenomyoepithelial tumours in benign, borderline and malignant was supported by results of CGH, any assessment of prognosis requires to be firmly based on morphological grounds.
  • [MeSH-minor] Actins / biosynthesis. Adult. Aged. Aged, 80 and over. Cell Proliferation. DNA-Binding Proteins. Female. Genes, Tumor Suppressor. Humans. Image Processing, Computer-Assisted. Immunohistochemistry. Immunophenotyping. Keratins / biosynthesis. Microscopy, Fluorescence. Middle Aged. Nucleic Acid Hybridization. Phosphoproteins / biosynthesis. Prognosis. Trans-Activators / biosynthesis. Transcription Factors. Tumor Suppressor Proteins. Vimentin / biosynthesis

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  • (PMID = 16050957.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / Vimentin; 68238-35-7 / Keratins
  • [Other-IDs] NLM/ PMC1187882
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4. Khan KN, Kitajima M, Hiraki K, Fujishita A, Nakashima M, Ishimaru T, Masuzaki H: Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma. Hum Reprod; 2010 Nov;25(11):2878-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma.
  • BACKGROUND: We recently demonstrated the effect of gonadotrophin-releasing hormone agonist (GnRHa) on tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma.
  • Here, we investigated expression of GnRH receptors (GnRHRs) and effect of GnRHa on the proliferation of cells derived from endometria and pathological lesions of women with these reproductive diseases.
  • METHODS: Biopsy specimens were collected from lesions and corresponding endometria of 35 women with pelvic endometriosis, 45 women with ovarian endometrioma, 35 women with adenomyosis and 56 women with uterine myoma during laparoscopy or laparotomy.
  • RESULTS: Types I and II GnRHRs mRNA and proteins were expressed in eutopic endometria and pathological lesions derived from women with endometriosis, adenomyosis and uterine myoma.
  • CONCLUSIONS: Local tissue expression of GnRHR was detected in endometriosis, adenomyosis and uterine myoma.
  • In addition to a hypo-estrogenic effect, a direct anti-proliferative effect of GnRHa may be involved in the regression of these reproductive diseases with consequent remission of clinical symptoms.


5. Kubo M, Ihn H, Yamane K, Tamaki K: The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans. Br J Dermatol; 2006 May;154(5):919-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are benign and intermediate malignant fibrotic dermal tumours, respectively.
  • The contribution of transforming growth factor (TGF)-beta has been implicated in the progression of sclerosis in fibrotic diseases.
  • RESULTS: We detected strong expression of TGFbeta-RI and TGFbeta-RII on epidermis and epidermal appendages, moderate expression in vascular endothelial cells, smooth muscle cells and neural tissues, and weak expression in fibroblasts in normal skin sections.
  • The expression of TGFbeta-RI and TGFbeta-RII was decreased in DFSP in comparison with DF, and their expression was found to be homogeneous in each DFSP tumour cell.
  • The staining for TGF-beta1 was found prominently on matrix and spindle-shaped tumour cells of DF, and peripheral regions of DFSP.
  • Weak expression of TGF-beta1 was found on normal skin or tumour cells in the central part of DFSP.
  • Type I collagen expression was found on spindle-shaped tumour cells in DF, but not in tumour cells of DFSP.
  • The expression patterns of TGFbeta-RI and TGFbeta-RII may be helpful in distinguishing these diseases.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Neoplasm Proteins / metabolism. Receptors, Transforming Growth Factor beta / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Activin Receptors, Type I / genetics. Activin Receptors, Type I / metabolism. Adult. Biomarkers, Tumor / metabolism. Collagen Type I / metabolism. Diagnosis, Differential. Female. Humans. In Situ Hybridization. Male. Middle Aged. Protein-Serine-Threonine Kinases. RNA, Messenger / genetics. Skin / metabolism. Up-Regulation

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  • (PMID = 16634896.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / Receptors, Transforming Growth Factor beta; EC 2.7.1.11 / TGF-beta type I receptor; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / Activin Receptors, Type I; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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6. Chang WC, Chang DY, Huang SC, Shih JC, Hsu WC, Chen SY, Sheu BC: Use of three-dimensional ultrasonography in the evaluation of uterine perfusion and healing after laparoscopic myomectomy. Fertil Steril; 2009 Sep;92(3):1110-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENT(S): Ninety-seven women with symptomatic myomas warranting laparoscopic myomectomy.
  • The median myoma size was 8 cm, and median weight of the extirpated myomas was 250 g.
  • The median myoma volume was 262 cm(3), and median uterine volume was 380 cm(3).
  • However, an 11-cm(3) hypoechoic hematoma with poor tissue perfusion was still seen in 1 patient with a 720-cm(3) myoma.
  • CONCLUSION(S): Healing of a laparoscopic myomectomy scar can be evaluated by 3D-PDU.

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  • (PMID = 18976760.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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7. Cramer SF, Mann L, Calianese E, Daley J, Williamson K: Association of seedling myomas with myometrial hyperplasia. Hum Pathol; 2009 Feb;40(2):218-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of seedling myomas with myometrial hyperplasia.
  • Myometrial hyperplasia (MMH) is a common structural variation characterized by irregular zones of increased myometrial cellularity, with increased nucleus-cell ratios; but to date, there has been only anecdotal evidence that it may give rise to myomas.
  • We studied the relationship of seedling myomas to MMH in 50 consecutive hysterectomies and found that most seedling myomas (44/63, 70%) arose in MMH--35 in inframucosal MMH, 3 in subserosal MMH, and 6 from intramural MMH.
  • Some seedling myomas were incompletely circumscribed, seeming to arise not only in but also from MMH.
  • We suggest that even seedlings in normal myometrium may arise not from normal myometrial smooth muscle cells but rather from myometaplasia in intramural stromal emboli, with hyperplastic and then neoplastic transformation.

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  • (PMID = 18799191.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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8. Song T, Kim TJ, Kim MK, Park H, Kim JS, Lee YY, Kim CJ, Choi CH, Lee JW, Kim BG, Bae DS: Single port access laparoscopic-assisted vaginal hysterectomy for large uterus weighing exceeding 500 grams: technique and initial report. J Minim Invasive Gynecol; 2010 Jul-Aug;17(4):456-60
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  • DESIGN: A prospective single-center study (Canadian Task Force classification III).
  • MEASUREMENTS AND MAIN RESULTS: There were 11 cases with uterine myomas and 4 cases of adenomyosis.
  • The SPA procedure failed in 2 cases: 1 (uterine weight, 732 g) required 1 ancillary 5-mm port to manipulate with a myoma screw, and in the other we inserted 1 additional 15-mm port to use for a laparoscopic morcellator.
  • CONCLUSION: The SPA-LAVH procedure for a large uterus weighing in excess of 500 g was as safe and effective as the conventional LAVH.

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  • [Copyright] Copyright (c) 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20471918.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Chang FW, Yu MH, Ku CH, Chen CH, Wu GJ, Liu JY: Effect of uterotonics on intra-operative blood loss during laparoscopy-assisted vaginal hysterectomy: a randomised controlled trial. BJOG; 2006 Jan;113(1):47-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • POPULATION: One hundred and seventy-three women underwent LAVH for symptomatic uterine myomas and were randomly allocated to uterotonics (n = 91) or placebo (n = 82).
  • METHODS: Women underwent LAVH for symptomatic uterine myomas and were randomly assigned to receive either rectal misoprostol (400 microg) and intravenous oxytocin (10 IU/hour) or placebo during LAVH.

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  • (PMID = 16398771.001).
  • [ISSN] 1470-0328
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Oxytocics; 0E43V0BB57 / Misoprostol; 50-56-6 / Oxytocin
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10. Vargas SO, Korpershoek E, Kozakewich HP, de Krijger RR, Fletcher JA, Perez-Atayde AR: Cytogenetic and p53 profiles in congenital cystic adenomatoid malformation: insights into its relationship with pleuropulmonary blastoma. Pediatr Dev Pathol; 2006 May-Jun;9(3):190-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Congenital cystic adenomatoid malformation (CCAM), a developmental anomaly of lung, shares many features with the pediatric tumor pleuropulmonary blastoma (PPB).
  • Both may show benign epithelium-lined cysts and mesenchymal proliferation, often with skeletal muscle differentiation.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / genetics. Cystic Adenomatoid Malformation of Lung, Congenital / metabolism. Lung Neoplasms / genetics. Lung Neoplasms / metabolism. Pulmonary Blastoma / genetics. Pulmonary Blastoma / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Child, Preschool. Cytogenetics. DNA, Neoplasm / analysis. DNA, Neoplasm / isolation & purification. Female. Humans. Immunohistochemistry. Infant. Karyotyping. Male. Polymorphism, Single-Stranded Conformational. Prospective Studies

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  • (PMID = 16944975.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Tumor Suppressor Protein p53
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11. Yilmaz N, Sahin I, Kilic S, Ozgu E, Gungor T, Bilge U: Assessment of the predictivity of preoperative serum CA 125 in the differential diagnosis of uterine leiomyoma and uterine sarcoma in the Turkish female population. Eur J Gynaecol Oncol; 2009;30(4):412-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS: Uterine leiomyomas are the most common benign tumors of the uterus.
  • METHODS: The subjects of the study included a total of 2,382 patients aged between 20-71 years operated for uterine myoma between the years 2005 and 2008 at our hospital, and in the same period 26 patients diagnosed with uterine sarcoma who were assessed retrospectively.
  • CONCLUSION: We concluded that in the differential diagnosis of myoma and uterine sarcoma, the preoperative serum CA 125 level did not have any predictivity.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / blood. Carcinosarcoma / diagnosis. Carcinosarcoma / surgery. Diagnosis, Differential. Female. Humans. Middle Aged. Predictive Value of Tests. Young Adult


12. Klatsky PC, Lane DE, Ryan IP, Fujimoto VY: The effect of fibroids without cavity involvement on ART outcomes independent of ovarian age. Hum Reprod; 2007 Feb;22(2):521-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Neither the location (subserosal versus intramural) and the presence of multiple myomas nor the size of the myomas affected outcomes.

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  • [ErratumIn] Hum Reprod. 2007 Apr;22(4):1195
  • (PMID = 16997932.001).
  • [ISSN] 0268-1161
  • [Journal-full-title] Human reproduction (Oxford, England)
  • [ISO-abbreviation] Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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13. Avshalumov K, Williford P, Sangueza OP, Goldenberg G: Atypical fibroxanthoma presenting in a patient with stage III mycosis fungoides. J Dermatolog Treat; 2008;19(2):118-20
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  • The tumor was removed by MMS with clear margins.
  • The pathologic specimen revealed a relatively well-circumscribed neoplasm in the upper dermis composed of atypical spindle cells with pleomorphism, hyperchromatic nuclei, and brisk mitotic activity.
  • Immunohistochemical stains were focally positive for CD68, and negative for S-100, Melan-A, desmin, smooth muscle actin and neurofilament.
  • One year after the initial MMS, our patient developed another tumor on the right hand, which measured 4x6 mm.
  • This neoplasm underwent a fusiform excision with clear margins.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Mycosis Fungoides / pathology. Skin Neoplasms / pathology

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  • (PMID = 18484429.001).
  • [ISSN] 0954-6634
  • [Journal-full-title] The Journal of dermatological treatment
  • [ISO-abbreviation] J Dermatolog Treat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Agdi M, Valenti D, Tulandi T: Intraabdominal adhesions after uterine artery embolization. Am J Obstet Gynecol; 2008 Nov;199(5):482.e1-3
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  • The control group consisted of patients who underwent hysterectomy for uterine myoma in the same week.
  • In the UAE group, the diameter of the dominant myoma in patients with adhesions (11.3 +/- 1.9 cm) was larger than in those without adhesions (5.6 +/- 0.6 cm; P = .003; confidence interval, 1.9-8.5).
  • Large myoma predisposes to adhesion formation.

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  • (PMID = 18486095.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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15. Ozercan IH, Sahin N, Akdemir F, Onderci M, Seren S, Sahin K, Kucuk O: Chemoprevention of fibroid tumors by [-]-epigallocatechin-3-gallate in quail. Nutr Res; 2008 Feb;28(2):92-7
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  • This makes the quail a good animal model for screening potential agents for that aid in the prevention and treatment of human myoma uteri.
  • [MeSH-major] Anticarcinogenic Agents / pharmacology. Bird Diseases / prevention & control. Catechin / analogs & derivatives. Coturnix. Leiomyoma / prevention & control. Uterine Neoplasms / prevention & control
  • [MeSH-minor] Animals. Disease Models, Animal. Dose-Response Relationship, Drug. Female. Humans. Oviducts / pathology. Random Allocation

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  • (PMID = 19083394.001).
  • [ISSN] 1879-0739
  • [Journal-full-title] Nutrition research (New York, N.Y.)
  • [ISO-abbreviation] Nutr Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 8R1V1STN48 / Catechin; BQM438CTEL / epigallocatechin gallate
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16. Hayashi M, Tomita S, Fukasawa I, Inaba N: Large angioleiomyoma, rich of mast cell and sex hormone receptor expression. Arch Gynecol Obstet; 2009 Feb;279(2):193-7
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  • BACKGROUND: Angioleiomyoma is a rare benign solitary tumor, arising from the vascular smooth muscle.
  • This tumor usually occurs in the subcutis of extremities, uncommonly in abdomen, often presents as a small (<2 cm) and is treated with excision.
  • CASE: We report an extremely rare case of unusually large angioleiomyoma, first diagnosed as an ovarian tumor with some malignant possibilities by diagnostic imaging.
  • We resected 1.7 kg of tumor from the extra-peritoneal cavity in the lower abdomen.
  • CONCLUSION: This angioleiomyoma is not an obvious malignant tumor because of low mitosis, coagulative necrosis and cellular atypia.
  • There are some possibilities that sex hormones are related with the growth and degeneration of this case's tumor, because those receptors are strongly expressed in the nucleus of tumor cells.

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  • (PMID = 18449550.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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17. Mesquita AT, Santos CR, Gomez RS, Jorge J, León JE, de Almeida OP: Central granular cell odontogenic tumor: a histopathologic and immunohistochemical study. Ann Diagn Pathol; 2009 Dec;13(6):405-12
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  • [Title] Central granular cell odontogenic tumor: a histopathologic and immunohistochemical study.
  • The central granular cell odontogenic tumor (CGCOT) is a rare lesion that usually affects the posterior region of the mandible of young adults.
  • We present a case of CGCOT involving the mandible of a 20-year-old white woman, emphasizing the immunohistochemical characteristics using a large panel of antibodies.
  • The granular cells were positive for vimentin, CD68, lysozyme, muscle-specific actin, alpha-smooth muscle actin, calponin, neuron-specific enolase (NSE), CD138, and bcl-2.
  • These data confirm the benign nature of CGCOT, the association of OE with Langerhans cells, and a variable phenotype of the granular cells.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Granular Cell Tumor / metabolism. Mandibular Neoplasms / metabolism. Odontogenic Tumors / metabolism
  • [MeSH-minor] Disease-Free Survival. Female. Humans. Immunohistochemistry. Young Adult

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  • (PMID = 19917479.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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18. Danielson LS, Menendez S, Attolini CS, Guijarro MV, Bisogna M, Wei J, Socci ND, Levine DA, Michor F, Hernando E: A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell-related malignancy. Am J Pathol; 2010 Aug;177(2):908-17
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  • Smooth muscle (SM) is a spontaneously contractile tissue that provides physical support and function to organs such as the uterus.
  • Uterine smooth muscle-related neoplasia comprise common well-differentiated benign lesions called leiomyomas (ULM), and rare, highly aggressive and pleomorphic tumors named leiomyosarcomas (ULMS).
  • MicroRNAs (miRNAs) are small non-coding RNAs that play essential roles in normal cellular development and tissue homeostasis that can be used to accurately subclassify different tumor types.
  • Here, we demonstrate that miRNAs are required for full smooth muscle cell (SMC) differentiation of bone marrow-derived human mesenchymal stem cells (hMSCs).
  • Moreover, we show that this signature, along with miRNA profiles for ULMS and ULM, are able to subclassify tumors of smooth muscle origin along SM differentiation.

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  • (PMID = 20558575.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA138234; United States / NCRR NIH HHS / RR / UL1 RR025741; United States / NCI NIH HHS / CA / R01CA138234
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs
  • [Other-IDs] NLM/ PMC2913343
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19. García Rinaldi R, Pérez Hernández J, Corbalá AR, Aponte HR, Dayán V, Plaza M: Surgical treatment of multiple intracardiac and pulmonary artery tumor implants embolic from uterine intravascular leiomyomatosis. Bol Asoc Med P R; 2007 Jan-Mar;99(1):51-5
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  • [Title] Surgical treatment of multiple intracardiac and pulmonary artery tumor implants embolic from uterine intravascular leiomyomatosis.
  • Intravenous uterine leiomyomatosis is the invasion of the para-uterine veins by bundles of benign uterine muscle.
  • These muscle bundles can grow and extend directly to pelvic organs or embolize to the right cardiac chambers or pulmonary artery.
  • She was treated by excision of a 18cm mass from the right atrium, two masses from the right ventricle and a huge mass from the pulmonary artery.

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  • (PMID = 17616048.001).
  • [ISSN] 0004-4849
  • [Journal-full-title] Boletín de la Asociación Médica de Puerto Rico
  • [ISO-abbreviation] Bol Asoc Med P R
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Puerto Rico
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20. Marshburn PB, Matthews ML, Hurst BS: Uterine artery embolization as a treatment option for uterine myomas. Obstet Gynecol Clin North Am; 2006 Mar;33(1):125-44
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  • [Title] Uterine artery embolization as a treatment option for uterine myomas.
  • A prospective study of "contemporaneous cohorts," which excluded patients who had sub-mucosal and pedunculated subserosal myomas, sought to compare quality of life measures and adverse events in patients who underwent UAE or hysterectomy.
  • Furthermore, hysterectomy eliminates uterine bleeding and the risk for recurrence of myomas.
  • After McLucas advocated that gynecologists learn the skill to perform UAE for managing symptomatic myomas, the Society of Interventional Radiology responded with a precautionary commentary on the level of technical proficiency that is necessary to maintain optimum results from UAE.
  • The gynecologist is likely to be the primary initial consultant to patients who present with complaints of symptomatic myomas.
  • Because some women may experience ovarian failure after UAE, additional studies to determine basal follicle-stimulating hormone and estradiol before and after the procedure may provide insight into UAE-induced follicle depletion.UAE is a unique new treatment for uterine myomas, and is no longer considered investigational for symptomatic uterine fibroids.
  • There is international recognition that data are needed from RCTs that compare UAE with surgical alternatives.
  • FIBROID should provide critical data for the assessment of safety and outcomes measures for women who receive UAE for symptomatic uterine myomas.

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  • (PMID = 16504811.001).
  • [ISSN] 0889-8545
  • [Journal-full-title] Obstetrics and gynecology clinics of North America
  • [ISO-abbreviation] Obstet. Gynecol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 92
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21. Rana A, Gurung G, Amatya A, Khatri R: A simple new technique of performing myomectomy for a predominantly subserosal myoma quickly within few minutes. Kathmandu Univ Med J (KUMJ); 2007 Jan-Mar;5(1):110-1
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  • [Title] A simple new technique of performing myomectomy for a predominantly subserosal myoma quickly within few minutes.
  • Removing a degenerated myoma located around the uterine cornu by an innovative technique shelling the myoma a little away from the base by choice of a low placed incision, advantageous in terms of no requirement of blood transfusion because of the reduction in the surgical time is described in a 24 years old lady demanding a fertility conserving surgery.

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  • (PMID = 18603998.001).
  • [ISSN] 1812-2078
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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22. Bukulmez O, Doody KJ: Clinical features of myomas. Obstet Gynecol Clin North Am; 2006 Mar;33(1):69-84
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  • [Title] Clinical features of myomas.
  • Uterine myomas are the most common solid pelvic tumors in women and the primary indication for hysterectomy.
  • Most of the myomas are asymptomatic.
  • The most common symptoms associated with uterine myomas are abnormal uterine bleeding and pelvic discomfort mostly caused by the mass effect.
  • Uterine myomas have a significant role in reproductive dysfunction, although a causal relationship between infertility and intramural or subserosal myomas not disturbing the uterine cavity has not been established clearly.
  • Nevertheless myomas, especially the tumors distorting the uterine cavity, are associated with infertility and spontaneous miscarriage.
  • In addition, the myomas may be the potential cause for numerous obstetric complications, especially if they are located adjacent to placenta.
  • The transformation of myomas to leiomyosarcomas is a very rare event.
  • Despite the high prevalence of these tumors, there is paucity of data available regarding the natural clinical history of myomas.

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  • (PMID = 16504807.001).
  • [ISSN] 0889-8545
  • [Journal-full-title] Obstetrics and gynecology clinics of North America
  • [ISO-abbreviation] Obstet. Gynecol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 74
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23. Sato K, Oda Y, Ueda Y, Katsuda S: Fasciitis ossificans of the breast. Pathol Res Pract; 2007;203(10):737-9
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  • Spindle cells were immunoreactive for vimentin and alpha-smooth muscle actin, suggesting myofibroblastic differentiation.
  • To avoid an unnecessarily aggressive treatment, fasciitis ossificans, a benign bone-forming nodule, needs to be considered in the differential diagnosis of breast hard tumor.
  • [MeSH-major] Breast Diseases / diagnosis. Breast Neoplasms / diagnosis. Fasciitis / diagnosis. Incidental Findings. Ossification, Heterotopic / diagnosis

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  • (PMID = 17728072.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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24. Val-Bernal JF, Aguilera C, Villagrá NT, Correas MA: Myxoma of the renal capsule. Pathol Res Pract; 2005;200(11-12):835-40
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  • We describe a unique case of a clinically detected renal myxoma arising in the capsule.
  • A radiological examination incidentally discovered a right renal tumor.
  • The resected kidney contained a well-circumscribed gelatinous capsular tumor.
  • The tumor cells showed diffuse immunoreactivity for vimentin.
  • Occasional cells stained for alpha-smooth muscle actin and calponin.
  • No basal lamina was identified around the tumor cells.
  • The differential diagnosis includes many other benign and malignant soft-tissue lesions exhibiting prominent secondary myxoid features.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cell Nucleus / ultrastructure. Cytoplasmic Structures / ultrastructure. Humans. Immunoenzyme Techniques. Male. Nephrectomy. Treatment Outcome. Vimentin / analysis

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  • (PMID = 15792129.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
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25. Cobellis L, Pecori E, Rigatti F, Scaffa C, Rotondi M, Messalli EM: A rare case of female pelvic mass: angioleiomyoma of the broad ligament. Eur J Gynaecol Oncol; 2007;28(5):418-20
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  • Angioleiomyoma is a benign mesenchymal neoplasm composed of smooth muscle cells and thick-walled vessels.
  • Angioleiomyoma is a very rare tumor among the ever-expanding repertoire of growth variants described in benign uterine leiomyoma.
  • More rare is a solitary tumor of the broad ligament.
  • Thus angioleiomyoma of the broad ligament is an extremely rare benign tumor of the female pelvis.
  • The site of the benign mass was the left broad ligament of the uterus.
  • On pathologic examination of the specimen, the tumor was diagnosed as angioleiomyoma.
  • We present a case of angioleiomyoma of the broad ligament because of its extreme rarity and the large size of the tumor.
  • [MeSH-major] Adnexal Diseases / pathology. Angiomyoma / pathology. Broad Ligament

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  • (PMID = 17966227.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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26. Sun MJ, Cheng WL, Wei YH, Kuo CL, Sun S, Tsai HD, Lin HM, Liu CS: Low copy number and high 4977 deletion of mitochondrial DNA in uterosacral ligaments are associated with pelvic organ prolapse progression. Int Urogynecol J Pelvic Floor Dysfunct; 2009 Jul;20(7):867-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Uterosacral ligaments (UL) were obtained from 45 POP patients and 38 myoma patients without POP.
  • [MeSH-minor] Adult. Aged. Aging / metabolism. Biopsy. Case-Control Studies. Disease Progression. Female. Humans. Leiomyoma. Middle Aged. Muscle Weakness / metabolism. Muscle Weakness / physiopathology. Myoma. Sacrum. Uterine Neoplasms. Uterus

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  • (PMID = 19495551.001).
  • [Journal-full-title] International urogynecology journal and pelvic floor dysfunction
  • [ISO-abbreviation] Int Urogynecol J Pelvic Floor Dysfunct
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
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27. Visnovsky J, Zubor P, Galo S, Klobusiaková D, Fiolka R, Kajo K: [Validity of hysteroscopy in clinical setting: single centre analysis of 605 consecutive hysteroscopies]. Ceska Gynekol; 2008 Dec;73(6):365-9
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  • Hysteroscopy can be used for removal of polyps or myomas, endometrial tumor resection, synechiolysis, sterilisation or removal of remnants from pregnancy.
  • Multifactorial analysis of hysteroscopy, ultrasound and histopathological findings revealed 69.41% sensitivity rate for ultrasound finding of endometrial hyperplasia, 48.16% sensitivity rate for submucous myoma and 81.72% sensitivity for endometrial polyp.
  • The causally surgery (tumor or endometrium ablation, myoma or septum resection) was performed in 27.9% and in 5.65% others types of intrauterine hysteroscopic sugery were done.

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  • (PMID = 19170372.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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28. Moon H, Park SJ, Lee HB, Kim SR, Choe YH, Chung MJ, Jin GY, Lee YC: Pulmonary benign metastasizing leiomyoma in a postmenopausal woman. Am J Med Sci; 2009 Jul;338(1):72-4
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  • [Title] Pulmonary benign metastasizing leiomyoma in a postmenopausal woman.
  • Pulmonary benign metastasizing leiomyoma (BML) is a rare disease occurring predominantly in women of reproductive age and usually develops several years after the resection of a uterine leiomyoma.
  • A 52-year-old postmenopausal woman was admitted to our hospital because of a right-sided empyema.
  • A wedge biopsy revealed the pulmonary nodule consisting of branching glandular structures surrounded by abundant smooth muscle cells with no atypia.
  • We performed a gynecologic examination to identify the primary origin of the pulmonary smooth muscle tumors.
  • This is an interesting case of pulmonary BML identified simultaneously with uterine myoma in a postmenopausal woman.
  • [MeSH-minor] Female. Humans. Middle Aged. Neoplasm Metastasis. Postmenopause

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  • (PMID = 19506459.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Chien JC, Hsieh SC, Lee RC, Chen CY, Cheng CJ, Chan WP: Endometrial stromal sarcoma mimicking submucosal myoma protruding to the vagina: MRI findings. Eur J Gynaecol Oncol; 2005;26(6):657-60
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  • [Title] Endometrial stromal sarcoma mimicking submucosal myoma protruding to the vagina: MRI findings.
  • An incidental finding of severe anemia was also noted.
  • After two years, follow-up MRI showed a pedunculated mass protruding into the upper third of the vagina with a stalk connecting to the posterior wall of the uterine cavity, simulating submucosal myoma.
  • [MeSH-major] Endometrial Neoplasms / diagnosis. Myoma / diagnosis. Sarcoma, Endometrial Stromal / diagnosis

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  • (PMID = 16398232.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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30. Liu WM, Wang PH, Chou CS, Tang WL, Wang IT, Tzeng CR: Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas. Fertil Steril; 2007 Feb;87(2):356-61
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  • [Title] Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas.
  • OBJECTIVE: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone.
  • PATIENT(S): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus.
  • MAIN OUTCOME MEASURE(S): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups.
  • The recurrence rate of uterine myomas was 5.8% (3 of 52) in group I and 36.7% (11 of 30) in group II during an average follow-up period of 42.5 months.
  • CONCLUSION(S): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.
  • [MeSH-major] Laparoscopy / methods. Laparotomy / methods. Leiomyoma / surgery. Neoplasm Recurrence, Local / surgery. Uterine Neoplasms / surgery. Uterus / blood supply. Uterus / surgery

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  • [CommentIn] Fertil Steril. 2007 Sep;88(3):758-9; author reply 759 [17681320.001]
  • (PMID = 17069812.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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31. Nistal M, García-Cabezas MA, Castello MC, De Miguel MP, Regadera J: Age-related epididymis-like intratesticular structures: benign lesions of Wolffian origin that can be misdiagnosed as testicular tumors. J Androl; 2006 Jan-Feb;27(1):79-85
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  • [Title] Age-related epididymis-like intratesticular structures: benign lesions of Wolffian origin that can be misdiagnosed as testicular tumors.
  • The epithelial layer of ELITSs was surrounded by a thin layer of smooth-muscle cells.
  • The ELITSs are distinct from atrophic seminiferous tubules with a Sertoli cell-only pattern and from the benign glandular teratomatous component of an involution of a malignant testicular germ cell tumor, the so-called burn-out germ cell tumor.

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  • (PMID = 16400082.001).
  • [ISSN] 0196-3635
  • [Journal-full-title] Journal of andrology
  • [ISO-abbreviation] J. Androl.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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32. Liu WM, Wang PH, Tang WL, Wang IT, Tzeng CR: Uterine artery ligation for treatment of pregnant women with uterine leiomyomas who are undergoing cesarean section. Fertil Steril; 2006 Aug;86(2):423-8
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  • Reductions in the dominant myoma size (average: 45%) were demonstrated in group I patients postoperatively.


33. Takeuchi H, Kitade M, Kikuchi I, Shimanuki H, Kumakiri J, Takeda S: Influencing factors of adhesion development and the efficacy of adhesion-preventing agents in patients undergoing laparoscopic myomectomy as evaluated by a second-look laparoscopy. Fertil Steril; 2008 May;89(5):1247-53
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  • MAIN OUTCOME MEASURE(S): Evaluation of adhesions at the uterine wound and of de novo adhesions of the uterine adnexa by SLL.
  • RESULT(S): The SLL revealed uterine surgical wound adhesions in 141 patients (37.9%) and de novo adhesions of the uterine adnexa in 33 patients (8.9%).
  • The results of analysis to determine the factors influencing the development of postoperative adhesions revealed that the diameter of the largest myoma, number of myomas, and type of adhesion-preventing agent used (except for fibrin sheath, which had no effect) influenced the incidence of postoperative adhesions at the surgical wound, but only the diameter of the largest myoma influenced the incidence of de novo adhesions of the uterine adnexa.
  • [MeSH-major] Fibrin Tissue Adhesive / therapeutic use. Laparoscopy / methods. Leiomyoma / surgery. Ovarian Diseases / etiology. Ovarian Diseases / prevention & control. Postoperative Complications. Uterine Neoplasms / surgery

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  • (PMID = 18155700.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cellulose, Oxidized; 0 / Fibrin Tissue Adhesive; 0 / INTERCEED
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34. Souza DP, Loureiro CC, Rejas RA, Sousa SO, Raitz R: Intraosseous myofibroma simulating an odontogenic lesion. J Oral Sci; 2009 Jun;51(2):307-11
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  • Myofibroma is a rare benign nodular tumor of the soft tissues, bones, or internal organs, and may affect both children and adults.
  • Histopathologic findings alone may be insufficient for a final diagnosis, and immunostaining for markers such as vimentin, alpha-smooth muscle actin, desmin and S-100 may be required.

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  • (PMID = 19550103.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Actins; 0 / Vimentin
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35. Miyake M, Tateishi U, Maeda T, Arai Y, Seki K, Sugimura K: Computed tomography and magnetic resonance imaging findings of soft tissue perineurioma. Radiat Med; 2008 Jul;26(6):368-71
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  • Soft tissue perineurioma is an uncommon benign peripheral nerve sheath tumor, although it is the most common subtype of perineuriomas.
  • We present a case of soft tissue perineurioma in the left groin of a 48-year-old man.

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  • [Cites] Muscle Nerve. 1999 Jan;22(1):28-36 [9883854.001]
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  • (PMID = 18677612.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Golan A, Zachalka N, Lurie S, Sagiv R, Glezerman M: Vaginal removal of prolapsed pedunculated submucous myoma: a short, simple, and definitive procedure with minimal morbidity. Arch Gynecol Obstet; 2005 Jan;271(1):11-3
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  • [Title] Vaginal removal of prolapsed pedunculated submucous myoma: a short, simple, and definitive procedure with minimal morbidity.
  • OBJECTIVE: Our objective was to evaluate the outcome of vaginal removal of prolapsed pedunculated submucous myomas over a 10-year period.
  • Fifty-two patients were admitted with the diagnosis of prolapsed pedunculated submucous myoma.
  • CONCLUSIONS: Vaginal myomectomy is the treatment of choice for prolapsed pedunculated submucous myoma.

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  • (PMID = 14999510.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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37. Ghert MA, Davis AM, Griffin AM, Alyami AH, White L, Kandel RA, Ferguson P, O'Sullivan B, Catton CN, Lindsay T, Rubin B, Bell RS, Wunder JS: The surgical and functional outcome of limb-salvage surgery with vascular reconstruction for soft tissue sarcoma of the extremity. Ann Surg Oncol; 2005 Dec;12(12):1102-10
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  • Each of these 19 patients was case-matched to 2 additional patients on the basis of tumor location, size, and depth; patient age; and timing of radiation.
  • RESULTS: Patients in the vascular reconstruction group were more likely to require a muscle transfer (53% vs. 18%; P = .008), experience a wound complication (68% vs. 32%; P = .03), experience deep venous thrombosis (26% vs. 0; P = .003), experience significant limb edema (87% vs. 20%; P = .001), and ultimately require an amputation (16% vs. 3%; P = .07).
  • There were no significant differences in local or systemic tumor relapse between the two groups.
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Histiocytoma, Benign Fibrous / surgery. Humans. Leg / innervation. Liposarcoma / surgery. Male. Middle Aged. Reconstructive Surgical Procedures. Recovery of Function. Retrospective Studies. Surgical Flaps. Treatment Outcome. Vascular Surgical Procedures

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  • (PMID = 16252136.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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38. McKinney CA, Geiger JD, Castle VP, Ruiz RE, Strouse PJ: Aggressive hepatic angiomyolipoma in a child. Pediatr Hematol Oncol; 2005 Jan-Feb;22(1):17-24
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  • Angiomyolipoma is a tumor of the kidney and, more rarely, the liver, which histologically consists of smooth muscle cells, adipose cells, and abnormal blood vessels in varying proportions.
  • This tumor is generally benign and resection is curative, but here the authors present the case of a 14-year-old girl with an unusual primary hepatic angiomyolipoma that recurred following resection and behaved aggressively.
  • Despite stabilization with a number of novel therapies, the child ultimately died of progressive disease.

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  • (PMID = 15770828.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Lee S, Le H, Munk P, Malfair D, Lee ChH, Clarkson P: Glomus tumour in the forearm: a case report and review of MRI findings. JBR-BTR; 2010 Nov-Dec;93(6):292-5
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  • [Title] Glomus tumour in the forearm: a case report and review of MRI findings.
  • Glomus tumours are uncommon benign neoplasms characterised by the proliferation of modified smooth muscle cells known as glomus cells.
  • We present a case of a solitary painful forearm lesion in an 81-year-old man, and review the English literature on extra-digital glomus tumours documenting MR imaging features.
  • [MeSH-major] Forearm. Glomus Tumor / diagnosis. Magnetic Resonance Imaging. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 21381525.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Belgium
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40. Chivukula M, Domfeh A, Carter G, Tseng G, Dabbs DJ: Characterization of high-grade ductal carcinoma in situ with and without regressive changes: diagnostic and biologic implications. Appl Immunohistochem Mol Morphol; 2009 Dec;17(6):495-9
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  • The presence of RC in these neoplasms may signify some degree of host response to tumor and seems to be a sign of poor prognosis for some neoplasms.
  • Reduced expression of myoepithelial markers (p63 and smooth muscle heavy chain myosin) were seen more frequently in the HGDCIS group with RC than without RC cases.
  • Invasion as well as metastatic disease was seen in association with HGDCIS with RC nearly 4 times as often.
  • It is also critically important to recognize HGDCIS-RC for diagnostic purposes, as the differential diagnosis of RC includes, benign associations such as papilloma, fibrocystic changes and periductal mastitis.

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  • (PMID = 19407654.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 13
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41. Mukhamed'ianov IF, Fedorov SV: [Clinical aspects of uterine artery embolization efficacy in uterine myomas]. Angiol Sosud Khir; 2010;16(2):43-6
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  • [Title] [Clinical aspects of uterine artery embolization efficacy in uterine myomas].
  • The authors have for the first time evaluated efficacy of embolization of the uterine arteries in uterine myomas depending on peculiarities of the blood flow in the system of the uterine arteries in the context of the B. B.

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  • (PMID = 21032872.001).
  • [ISSN] 1027-6661
  • [Journal-full-title] Angiologii︠a︡ i sosudistai︠a︡ khirurgii︠a︡ = Angiology and vascular surgery
  • [ISO-abbreviation] Angiol Sosud Khir
  • [Language] rus
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Russia (Federation)
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42. Palomba S, Zupi E, Zullo F: Fanfani F, et al. A prospective study of laparoscopy versus minilaparotomy in the treatment of uterine myomas. J Minim Invasive Gynecol; 2006 May-Jun;13(3):253; author reply 253-4
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  • [Title] Fanfani F, et al. A prospective study of laparoscopy versus minilaparotomy in the treatment of uterine myomas.

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  • [CommentOn] J Minim Invasive Gynecol. 2005 Nov-Dec;12(6):470-4 [16337572.001]
  • (PMID = 16698538.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fertility Agents, Female; 33515-09-2 / Gonadotropin-Releasing Hormone
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43. Abdul Ghaffar NA, Ismail MP, Nik Mahmood NM, Daud K, Abu Dzarr GA: Huge uterine fibroid in a postmenopausal woman associated with polycythaemia: a case report. Maturitas; 2008 Jun 20;60(2):177-9
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  • Uterine fibroid or leiomyoma is the commonest benign uterine tumour.
  • A case of a postmenopausal woman with a huge uterine fibroid associated with polycythaemia is presented whereby the mass was noted to increase in size within 2 years.
  • It was suggested that large uterine myoma may cause secondary polycythaemia by three postulated mechanisms, i.e. presence of hypoxia suggesting shunting within the tumour, second, the uterine fibroid was compressing the ureters resulting in inappropriate excessive production of erythropoietin by the kidneys, and third, the tumour itself may have been producing the erythropoietin.


44. Alborzi S, Parsanezhad ME, Mahmoodian N, Alborzi S, Alborzi M: Sonohysterography versus transvaginal sonography for screening of patients with abnormal uterine bleeding. Int J Gynaecol Obstet; 2007 Jan;96(1):20-3
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  • CONCLUSIONS: In this study SIS was more sensitive and specific in diagnosing polyp, myoma and adenomyosis with high positive and negative predictive value.

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  • (PMID = 17187802.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
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45. Zúbor P, Kajo K, Dussan CA, Szunyogh N, Danko J: Rapidly growing nodular pseudoangiomatous stromal hyperplasia of the breast in an 18-year-old girl. APMIS; 2006 May;114(5):389-92
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  • Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a rare benign proliferation of mesenchymal stromal cells with irregular slit-like formations resembling angiomatous structures.
  • In the majority of cases this lesion is a focal microscopic finding in breast biopsies performed for benign or malignant diseases.
  • The exact etiology and pathogenesis of this tumor-like lesion is still unknown, but a proliferative response of myofibroblasts to hormonal stimuli has been postulated.
  • [MeSH-major] Breast / cytology. Breast / pathology. Breast Neoplasms / diagnosis. Neoplasms, Muscle Tissue / pathology

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  • (PMID = 16725017.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 4G7DS2Q64Y / Progesterone
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46. Pritts EA, Parker WH, Olive DL: Fibroids and infertility: an updated systematic review of the evidence. Fertil Steril; 2009 Apr;91(4):1215-23
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  • RESULT(S): Women with subserosal fibroids had no differences in their fertility outcomes compared with infertile controls with no myomas, and myomectomy did not change these outcomes compared with women with fibroids in situ.
  • Removal of submucous myomas appears likely to improve fertility.


47. Maia H Jr, Casoy J, Pimentel K, Correia T, Athayde C, Cruz T, Coutinho EM: Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologies. Contraception; 2008 Dec;78(6):479-85
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  • [Title] Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologies.
  • BACKGROUND: The study was conducted to evaluate vascular endothelial growth factor (VEGF), Cox-2 and aromatase expression in the endometrium of uteri with myomas and other associated pathologies.
  • STUDY DESIGN: Hysteroscopy was performed in 118 women of reproductive age with myomas and menorrhagia, 40 of whom were using a pill containing 75 mcg gestodene+30 mcg ethinylestradiol.
  • RESULTS: In patients with myomas and menorrhagia, associated pathologies such as adenomyosis, endometrial polyps and endometriosis were found in 32%, 12% and 17% of cases, respectively.
  • CONCLUSION: Endogenous progesterone or combined oral contraceptives are potent inhibitors of VEGF, aromatase and Cox-2 expression in the endometrium of patients with myomas and menorrhagia.

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  • (PMID = 19014794.001).
  • [ISSN] 1879-0518
  • [Journal-full-title] Contraception
  • [ISO-abbreviation] Contraception
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral; 0 / Vascular Endothelial Growth Factor A; 4G7DS2Q64Y / Progesterone; EC 1.14.14.1 / Aromatase; EC 1.14.99.1 / Cyclooxygenase 2
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48. Dolores-Velázquez R, Lever-Rosas CD, Barrera-Franco JL, Padilla-Rosciano A, Frias-Mendivil M, Dominguez-Parra L: [Primary benign chest wall tumors: results of surgical treatment]. Cir Cir; 2007 Nov-Dec;75(6):419-24
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  • [Title] [Primary benign chest wall tumors: results of surgical treatment].
  • [Transliterated title] Tumores primarios benignos de la pared torácica: resultados del tratamiento quirúrgico.
  • BACKGROUND: We undertook this study to describe the clinical characteristics of primary benign chest wall tumors and to evaluate the results of surgical treatment.
  • METHODS: We included patients with primary benign chest wall tumors who underwent surgical resection at the Instituto Nacional de Cancerología from January 1990 to December 2002.
  • All patients had histological confirmation of benign tumor.
  • The most frequent tumor was chondroma in seven cases (41%), followed by aponeurotic-muscle fibromatosis in five (30%) and the remaining five patients had other tumor types.
  • Of the 17 patients, 16 are alive without disease and one presented delayed recurrence with an aponeurotic-muscle fibromatosis requiring a new thoracic wall resection.
  • CONCLUSIONS: Primary benign chest wall tumors are locally aggressive and must be treated with wide resection of the thoracic wall.

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  • (PMID = 18177561.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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49. Lanza A, Moscariello A, Villani R, Colella G: Glomus tumor of the lower lip. A case report. Minerva Stomatol; 2005 Nov-Dec;54(11-12):687-90
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  • [Title] Glomus tumor of the lower lip. A case report.
  • A glomus tumor is a benign neoplasm originating from the modified smooth muscle cells of the vascular glomus.
  • This neoplasm was firstly considered by Masson in 1924, and generally it has a solitary lesions but in some cases multiple lesions were described.
  • The clinical case of a 65-year-old man with a glomus tumor of the lower lip is described.
  • [MeSH-major] Glomus Tumor / pathology. Lip Neoplasms / pathology

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  • (PMID = 16456522.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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50. Erman-Akar M, Mullany S, Huffman J, Yalcinkaya TM: Early postoperative small bowel obstruction after laparoscopic myomectomy. Fertil Steril; 2010 Nov;94(6):2329.e9-12
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  • PATIENT(S): Two days after a robotic-assisted laparoscopic myomectomy, a 35-year-old nulligravid African-American woman developed a small bowel obstruction due to retained myoma fragments that had implanted on and subsequently kinked loops of the small bowel.
  • Due to worsening clinical symptoms and supportive radiologic findings, exploratory laparotomy was performed to lyse adhesions and remove the implanted myoma pieces.
  • To reduce the risk of ectopic implantation of myoma fragments, meticulous care should be taken to remove all remnants of morcellated tissue.
  • Immediate postoperative complications, such as bowel obstruction, and long-term complications related to recurrent myomas may then be avoided.

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20416869.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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51. Varma R, Soneja H, Clark TJ, Gupta JK: Hysteroscopic myomectomy for menorrhagia using Versascope bipolar system: efficacy and prognostic factors at a minimum of one year follow up. Eur J Obstet Gynecol Reprod Biol; 2009 Feb;142(2):154-9
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  • STUDY DESIGN: Prospective observational study set in a university teaching hospital in UK involving 92 women symptomatic of HMB with submucous myomas consecutively recruited between June 2003 and November 2006.
  • CONCLUSION: HMB with submucous myomas may be successfully treated by completely removing the intracavity myoma component, irrespective of co-existent intramural or subserosal fibroids or size of fibroid resected.

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  • (PMID = 19036492.001).
  • [ISSN] 1872-7654
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
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52. Chaplin A, Conrad DM, Tatlidil C, Jollimore J, Walsh N, Covert A, Pasternak S: Primary cutaneous PEComa. Am J Dermatopathol; 2010 May;32(3):310-2
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  • A 48-year-old woman attended a physician because of a solitary cutaneous nodule on the left lower leg.
  • Microscopic examination of the excisional specimen revealed a dermal tumor composed of nests of epithelioid cells exhibiting clear cytoplasm.
  • The tumor showed an infiltrative border.
  • Immunohistochemical evaluation revealed that the tumor cells were positive for HMB-45 and microftalmia associated transcription factor (MITF).
  • The tumor cells were negative for S-100 protein, alfa smooth muscle actin, HHF-35, and various cytokeratins.
  • The case is one of a primary cutaneous pecoma.
  • They constitute a spectrum of lesions in different organs including angiomyolipoma of the kidney and liver, sugar tumor of the lung, lymphangiomatosis, and lymphangiomyoma.
  • Follow-up data is limited but they appear to behave in a benign fashion.
  • We report an additional case with the goal of alerting dermatopathologists to this distinctive unusual neoplasm.
  • [MeSH-minor] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Biopsy. Desmin / analysis. Female. Humans. Leg. Melanoma-Specific Antigens. Microphthalmia-Associated Transcription Factor / analysis. Middle Aged. Neoplasm Proteins / analysis. Treatment Outcome

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  • (PMID = 20139753.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / MITF protein, human; 0 / Melanoma-Specific Antigens; 0 / Microphthalmia-Associated Transcription Factor; 0 / Neoplasm Proteins
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53. Shannon BA, Cohen RJ, Segal A, Baker EG, Murch AR: Clear cell renal cell carcinoma with smooth muscle stroma. Hum Pathol; 2009 Mar;40(3):425-9
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  • [Title] Clear cell renal cell carcinoma with smooth muscle stroma.
  • A recent publication described 5 unusual clear cell renal tumors with prominent smooth muscle stroma that were characterized only by immunostaining.
  • We report 3 additional tumors composed of clear cell renal cell carcinoma intimately admixed with abundant smooth muscle stroma.
  • Epithelial differentiation of the malignant clear cell components and smooth muscle differentiation of the benign spindle cell stroma was confirmed by the immunostaining profiles and by electron microscopy.
  • Extensive tissue sampling and immunostaining are recommended to distinguish cases with an extensive smooth muscle component from morphologically similar but benign lesions including angiomyolipoma, leiomyoma, or mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Kidney Neoplasms / pathology. Muscle, Smooth / pathology. Stromal Cells / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Chromosome Deletion. Chromosomes, Human, Pair 3. Disease-Free Survival. Female. Humans. In Situ Hybridization, Fluorescence. Male. Microscopy, Electron, Transmission. Middle Aged. Nephrectomy


54. Pollio F, Staibano S, Mansueto G, De Rosa G, Persico F, De Falco M, Di Lieto A: Erythropoietin and erythropoietin receptor system in a large uterine myoma of a patient with myomatous erythrocytosis syndrome: possible relationship with the pathogenesis of unusual tumor size. Hum Pathol; 2005 Jan;36(1):120-7
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  • [Title] Erythropoietin and erythropoietin receptor system in a large uterine myoma of a patient with myomatous erythrocytosis syndrome: possible relationship with the pathogenesis of unusual tumor size.
  • Substantial myoma size has been noted as a common denominator in this condition in which recent evidence have confirmed erythropoietin (Epo) production by myoma tissues themselves.
  • In this paper, we researched on Epo and, as a first in the literature, Epo-R immunoexpression in a large uterine myoma of a term pregnant patient suffering from the myomatous erythrocytosis syndrome.
  • Apart from confirming Epo production by myoma smooth muscle cells in the myomatous erythrocytosis syndrome, we reveal in this pathologic condition a characteristic strong Epo-R expression in myoma endothelial cells and a weak and sporadic Epo-R expression in myoma smooth muscle cells.
  • The striking presence of Epo-R within myoma tissues in the case of the myomatous erythrocytosis syndrome allows us to speculate that myoma Epo production, besides determining erythrocytosis through systemic effects, may contribute, acting by autocrine and paracrine mechanisms, in determining the large myoma size almost always observed in this condition.
  • Finally, we confirm a less but specific immunostaining for Epo in uterine myomas of patients without erythrocytosis and, as a first in the literature, we prove a weak and sporadic Epo-R expression in these lesions.
  • These last results may contribute to knowledge of the yet unclear etiopathogenesis of the most common human gynecologic neoplasm.

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  • (PMID = 15712191.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Erythropoietin; 11096-26-7 / Erythropoietin
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55. Trapeznikova MF, Bazaev VV, Vishniakova MM, Bychkova NV, Urenkov SB, Nikulina ES: [Successful combined surgical treatment double giant ureterocele complicated by double ureterohydronephrosis, cascade lithiasis and uterine myomatosis]. Urologiia; 2009 Jul-Aug;(4):58-61
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  • A case is reported of a 58 year old patient with a diagnosis: double giant ureterocele, secondary multiple calculi of the right ureterocele, calculus of the inferior calyx of the right kidney, calculus of the terminal part of the left ureter, double ureterohydronephrosis, chronic pyelonephritis, multiple calcifying myoma of the uterus.

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  • (PMID = 19824387.001).
  • [ISSN] 1728-2985
  • [Journal-full-title] Urologii︠a︡ (Moscow, Russia : 1999)
  • [ISO-abbreviation] Urologiia
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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56. Meshkova IE, Volkova AV, Semenov II: [Features of ultrasound diagnosis of non-epithelial ovarian carcinoma]. Vopr Onkol; 2007;53(3):345-51
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  • Ultrasound examination using color Doppler imaging was used in 70 patients with non-epithelial ovarian carcinoma and 23 patients with subserous nodes of uterine myoma.
  • The procedure can be used for differentiated diagnosis between non-epithelial ovarian carcinoma and subserous nodes of uterine myoma, as well as for appraisal of individual features of tumor so that adequate treatment might be selected.
  • [MeSH-major] Myoma / ultrasonography. Ovarian Neoplasms / ultrasonography

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  • (PMID = 18198619.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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57. Lin MS, Hung YS, Wu HH, Kuo MC, Shiu TF, Chuang CK, Shih LY, Chu PH: Polycythemia vera as a presentation of renal angiomyolipoma: a case report. J Med Case Rep; 2009;3:90
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  • INTRODUCTION: Angiomyolipoma is a common benign renal tumor composed of thick-walled blood vessels, smooth muscle, and adipose tissue.
  • It may be found incidentally during workup for suspected renal disease.
  • This report describes a rare case of a woman diagnosed with renal angiomyolipoma and polycythemia vera.
  • Surgical intervention for this renal tumor should be avoided unless malignancy or renal cell carcinoma is suspected or to prevent spontaneous rupture of larger tumors.

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  • [Cites] Hematology. 2007 Apr;12(2):123-30 [17454193.001]
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  • (PMID = 19946506.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2783089
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58. Premalata CS, Kumar RV, Saleem KM, Fathima LJ, Das K: Fetal rhabdomyoma of the lower extremity. Pediatr Blood Cancer; 2009 Jul;52(7):881-3
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  • Fetal rhabdomyoma is a benign tumor of the skeletal muscle, showing varying degrees of skeletal muscle maturation.

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19165887.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Ouellet P, Bergeron ME, Lapointe D, Laberge P, Côté M: [Severe hyponatremia associated with transcervical resection of a uterine myoma]. Can J Anaesth; 2010 Feb;57(2):181-2
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  • [Title] [Severe hyponatremia associated with transcervical resection of a uterine myoma].
  • [Transliterated title] Hyponatrémie sévère au cours d'une résection endoscopique d'un myome utérin.

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  • [CommentOn] Can J Anaesth. 2009 Apr;56(4):316-9 [19252964.001]
  • (PMID = 19904578.001).
  • [ISSN] 1496-8975
  • [Journal-full-title] Canadian journal of anaesthesia = Journal canadien d'anesthésie
  • [ISO-abbreviation] Can J Anaesth
  • [Language] fre
  • [Publication-type] Comment; Comparative Study; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, General; 0 / Anesthetics, Local; TE7660XO1C / Glycine
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60. McLucas B: Diagnosis, imaging and anatomical classification of uterine fibroids. Best Pract Res Clin Obstet Gynaecol; 2008 Aug;22(4):627-42
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  • [Title] Diagnosis, imaging and anatomical classification of uterine fibroids.
  • The correct identification of myomata and the exclusion of other diseases, especially malignancies, are imperative when evaluating therapy options.
  • A confident diagnosis of myomata may be aided by several imaging modalities.
  • Imaging can provide information regarding precise myomata location, which may, in turn, dictate treatment options.
  • Myomata may be classified based upon position within the uterus, and may be further described by phase of degeneration.
  • With the increasing popularity of uterine-conserving therapy, accurate diagnosis of myomata becomes even more important.

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  • (PMID = 18328787.001).
  • [ISSN] 1521-6934
  • [Journal-full-title] Best practice & research. Clinical obstetrics & gynaecology
  • [ISO-abbreviation] Best Pract Res Clin Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 61
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61. Sinha R, Sundaram M: Laparoscopic management of large myomas. J Gynecol Endosc Surg; 2009 Jul;1(2):73-82
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  • [Title] Laparoscopic management of large myomas.
  • The objective of this article is to review the different techniques that have been adopted for removal of large myomas laparoscopically.
  • We have also quoted literature about the impact of myomas on Pregnancy and obstetrical outcome and the effect of laparoscopic myomectomy on the same.
  • Technical modifications to remove large myomas have been described along with methods to reduce intraoperative bleeding.

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  • (PMID = 22442517.001).
  • [ISSN] 0974-1216
  • [Journal-full-title] Journal of gynecological endoscopy and surgery
  • [ISO-abbreviation] J Gynecol Endosc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3304276
  • [Keywords] NOTNLM ; Laparoscopic myomectomy / fibroids / large myomas / pregnancy after myomectomy / uterine artery ligation
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62. Liang Z, Xu H, Chen Y, Li Y, Zhang Q: Laparoscopic blockage of uterine artery and myomectomy: a new method of treating symptomatic uterine leiomyomas. Surg Endosc; 2006 Jun;20(6):983-6
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  • BACKGROUND: The goal of this study was to evaluate the effects of laparoscopic coagulation or blockage of the uterine arteries and myomectomy in treating symptomatic myomas.
  • RESULTS: Most of the 142 patients had multi-myomas of the uterus, as intramural myomas (54), subserous myomas (65), and submucosal myomas (25).
  • The number of myomas in each patient varied from 1 to 4.
  • The size of the myomas in all patients ranged from 2 to 12 cm.
  • Five patients experienced recurrence of myomas.
  • CONCLUSIONS: Laparoscopic coagulation or block of the uterine arteries and myomectomy appears to be a safe, effective, and promising new method for treating symptomatic uterine myomas.
  • [MeSH-minor] Adult. Arteries / surgery. Female. Humans. Incidence. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Treatment Outcome

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  • (PMID = 16738997.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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63. Lin CK, Chu TW, Yu MH: Painless ovarian torsion mimicking a uterine myoma. Taiwan J Obstet Gynecol; 2006 Dec;45(4):340-2
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  • [Title] Painless ovarian torsion mimicking a uterine myoma.
  • OBJECTIVE: Uterine myoma is the most common benign solid pelvic tumor seen in women and is easily demonstrated by pelvic ultrasonography.
  • We herein present an unusual case of painless ovarian torsion similar to a subserous uterine myoma.
  • Ultrasound revealed a well-defined, heterogeneous solid mass with echogenic rim that resembled a uterine myoma, 10.9 x 9.9 x 7.3 cm in size, just upon the uterus.
  • Although there may be no specific indication, the diagnosis of ovarian torsion should be considered on finding a pelvic mass.
  • [MeSH-major] Leiomyoma / diagnosis. Ovarian Diseases / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Torsion Abnormality / diagnosis

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  • (PMID = 17175495.001).
  • [ISSN] 1875-6263
  • [Journal-full-title] Taiwanese journal of obstetrics & gynecology
  • [ISO-abbreviation] Taiwan J Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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64. Hammoud AO, Asaad R, Berman J, Treadwell MC, Blackwell S, Diamond MP: Volume change of uterine myomas during pregnancy: do myomas really grow? J Minim Invasive Gynecol; 2006 Sep-Oct;13(5):386-90
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  • [Title] Volume change of uterine myomas during pregnancy: do myomas really grow?
  • STUDY OBJECTIVE: To estimate changes in uterine myoma volume during pregnancy.
  • Canadian Task Force Classification II-3.
  • PATIENTS: One hundred-seven patients diagnosed with uterine myomas during pregnancy and who had two or more obstetrical ultrasounds in different periods of pregnancy.
  • INTERVENTIONS: We analyzed the change in volume of uterine myomas between the first half of pregnancy (up until 19 weeks), third quarter (20-30 weeks), and last quarter (31 weeks to term).
  • The volume of largest uterine myoma was calculated using the formula Volume (mm3)=Pi/6x(length mm)x(width mm)x(height mm).
  • Between the first and the second study periods, the percentage of uterine myomas that decreased in size was 55.1% (95% CI: 43-66), with a mean decrease in volume of 35%+/-4%; while the percentage of uterine myomas that enlarged was 44.9% (95% CI: 34-56), with a mean increase in volume of 69%+/-11%.
  • CONCLUSION: Contrary to common belief, we found that uterine myomas commonly decrease in volume over the course of pregnancy.
  • [MeSH-major] Leiomyoma / pathology. Pregnancy Complications, Neoplastic / pathology. Tumor Burden. Uterine Neoplasms / pathology


65. Kuzel D, Toth D, Cindr J, Bartosova L, Mara M, Viklicky O: Minimally invasive and hysteroscopic diagnosis and treatment of patients after organ transplantation. J Obstet Gynaecol Res; 2009 Apr;35(2):339-45
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  • METHODS: After kidney, pancreas, or liver transplantation, patients who presented with menorrhagia, submucosal myoma or thickened endometrium on ultrasound were diagnosed and treated using a hysteroscopic system Versascope, Bipolar Resectoscopic System and intrauterine system ThermaChoice.
  • CONCLUSION: Minimally invasive procedures and hysteroscopy of organ-transplanted patients provide a safe solution for the treatment of menorrhagia, submucosal myoma and thick endometrium in postmenopausal patients.

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  • (PMID = 19566489.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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66. Agaimy A, Wünsch PH, Schroeder J, Gaumann A, Dietmaier W, Hartmann A, Hofstaedter F, Mentzel T: Low-grade abdominopelvic sarcoma with myofibroblastic features (low-grade myofibroblastic sarcoma): clinicopathological, immunohistochemical, molecular genetic and ultrastructural study of two cases with literature review. J Clin Pathol; 2008 Mar;61(3):301-6
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  • AIMS: Low-grade myofibroblastic sarcoma (LGMS) represents a rare soft tissue neoplasm with a predilection for the head and neck.
  • Genomic DNA was isolated from microdissected formalin-fixed paraffin-embedded tumour tissue and examined for KIT and PDGFRA mutations by PCR and direct sequencing of KIT and PDGFRA.
  • The tumour cells strongly expressed vimentin, variably alpha-smooth muscle actin and fibronectin, but were negative for CD117, S-100, desmin, h-caldesmon, beta-catenin, ALK-1, MDM2, PDGFRalpha and PDGFRbeta.
  • One tumour showed a weak expression of CD34.
  • LGMS may mimic a variety of benign and low-grade malignant neoplasms and might be under-recognised.
  • [MeSH-major] Neoplasm Recurrence, Local / ultrastructure. Peritoneal Neoplasms / ultrastructure. Sarcoma / ultrastructure. Soft Tissue Neoplasms / ultrastructure
  • [MeSH-minor] Actins / analysis. Aged. Biomarkers, Tumor / analysis. DNA Mutational Analysis. Female. Fibronectins / analysis. Humans. Immunohistochemistry. Mesentery. Middle Aged. Mitotic Index. Pelvis. Proto-Oncogene Proteins c-kit / genetics. Receptor, Platelet-Derived Growth Factor alpha / genetics. Vimentin / analysis

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  • (PMID = 17513510.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Fibronectins; 0 / Vimentin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  • [Number-of-references] 38
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67. Payson M, Leppert P, Segars J: Epidemiology of myomas. Obstet Gynecol Clin North Am; 2006 Mar;33(1):1-11
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  • [Title] Epidemiology of myomas.
  • Fibroids are a prevalent disorder occurring in at least half of American reproductive-age women.
  • Most women never attribute or report any symptoms from their fibroids, and because of this the actual contribution of disease to symptoms of pelvic pain,menstrual symptoms, and infertility is poorly understood.
  • Controlling for fibroid disease may explain this disparity, at least in part.
  • Fundamental and significant questions remain about fibroid disease,such as whether different clinical disease phenotypes (multiple versus single leiomyomas) contribute equally to symptoms and possess an equal likelihood of disease progression.
  • For epidemiologic assessment of disease, a scoring system is urgently needed.
  • Well-designed, controlled, prospective studies are still needed to define the natural history and correlate the presence of disease with symptomatology in women.

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  • (PMID = 16504803.001).
  • [ISSN] 0889-8545
  • [Journal-full-title] Obstetrics and gynecology clinics of North America
  • [ISO-abbreviation] Obstet. Gynecol. Clin. North Am.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 HD999999
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Number-of-references] 34
  • [Other-IDs] NLM/ NIHMS618967; NLM/ PMC4152898
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68. Sinha R, Sundaram M, Lakhotia S, Mahajan C, Manaktala G, Shah P: Total laparoscopic hysterectomy for large uterus. J Gynecol Endosc Surg; 2009 Jan;1(1):34-9
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  • We have analyzed whether it is possible for an experienced laparoscopic surgeon to perform efficient total laparoscopic hysterectomy for large myomatous uteri regardless of the size, number and location of the myomas.
  • DESIGN: Retrospective review (Canadian Task Force Classification II-1) SETTING: Dedicated high volume Gynecological laparoscopy centre.
  • PATIENTS: 173 women with symptomatic myomas who underwent total laparoscopic hysterectomy at our center.
  • There were no exclusion criteria based on the size number or location of myomas.
  • It can be performed by experienced surgeons for large uteri regardless of the size, number or location of the myomas.

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  • (PMID = 22442509.001).
  • [ISSN] 0974-1216
  • [Journal-full-title] Journal of gynecological endoscopy and surgery
  • [ISO-abbreviation] J Gynecol Endosc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3304266
  • [Keywords] NOTNLM ; Large uterus / multiple fibroids / total laparoscopic hysterectomy
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69. Zhu Y, Cuevas IC, Gabriel RA, Su H, Nishimura S, Gao P, Fields A, Hao Q, Young WL, Yang GY, Boudreau NJ: Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain. J Neuropathol Exp Neurol; 2009 Jun;68(6):626-32
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  • Hemangiomas are angiogenesis-dependent benign vascular tumors that can rupture and cause intracranial hemorrhages.
  • The EOMA cells induced brain hemangiomas characterized by large cystlike spaces lined by thin walls of endothelial cells surrounded by scant smooth muscle cells.

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  • (PMID = 19458547.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / R21 NS050668-02; United States / NINDS NIH HHS / NS / P01 NS044155-05; United States / NINDS NIH HHS / NS / R21 NS050668; United States / NINDS NIH HHS / NS / P01 NS044155; United States / NINDS NIH HHS / NS / R01 NS027713; United States / NINDS NIH HHS / NS / R01 NS27713; United States / NINDS NIH HHS / NS / NS044155-05; United States / NINDS NIH HHS / NS / NS027713-17; United States / NINDS NIH HHS / NS / R21 NS50668; United States / NINDS NIH HHS / NS / P01 NS44145; United States / NINDS NIH HHS / NS / R01 NS027713-17; United States / NINDS NIH HHS / NS / NS050668-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Hif1a protein, mouse; 0 / Homeodomain Proteins; 0 / Hoxa5 protein, mouse; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Lectins; 0 / Phosphoproteins; 0 / RNA, Messenger; 0 / Thrombospondins; 0 / thrombospondin 2
  • [Other-IDs] NLM/ NIHMS118393; NLM/ PMC2728585
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70. Georgiev D, Iankov M, Katsulov A, Vasileva M: [Myoma uteri permagna in pregnancy--a case report and clinical practice]. Akush Ginekol (Sofiia); 2005;44 Suppl 1:6-7
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  • [Title] [Myoma uteri permagna in pregnancy--a case report and clinical practice].


71. Káram-Orantes M, Fonte-Avalos V, Zuloaga-Salcedo S, Domínguez-Cherit J: [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006]. Gac Med Mex; 2007 Sep-Oct;143(5):371-5
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  • [Title] [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006].
  • [Transliterated title] Frecuencia de tumores benignos durante el periodo de 2000-2006 en el Hospital General "Dr. Manuel Gea González".
  • BACKGROUND: Benign skin neoplasms are defined as autonomous growing tissue unrelated to normal growing of the skin, that persist even after the originating stimulus dissapears.
  • Almost all human beings have a certain number of benign cutaneous neoplasms and many never seek medical attention.
  • The aim of this study was to record the number of benign tumors studied at the Dermatology Department of a medical facility.
  • We included year of admission, number of biopsies, sex, age, tumor location, histological and clinical diagnoses.
  • RESULTS: We analyzed 9,436 biopsies of which 3,765 constituted benign neoplasms; 595 were not included and our total sample was 3,170 tumors.
  • The most frequent tumors according to histopathological diagnoses in descending order were: melanocytic, cutaneous cysts, fibrous tumors, vascular tumors, epidermal tumors, fat tumors, tumors with hair differentiation, neural tumors, glandular tumors, tumors with sebaceous differentiation, cartilage and bone tumors, and smooth muscle tumors.
  • The most common benign tumors were: Melanocytic nevi, epidermal cysts, seborrheic keratoses, pyogenic granulomas, lipomas and dermatofibromas.
  • CONCLUSIONS: Melanocytes represented by melanocytic nevi (junctional, intradermic and compound) were the most frequent benign neoplasms, followed by epidermoid cysts.
  • Our results illustrate the most common benign tumors observed in a dermatology department.

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  • (PMID = 18246930.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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72. Chiu YC, Lin JW, Changchien CS, Huang CC, Liu SY, Yi LN, Chiu KW, Wu KL, Chen YY, Chou FF, Hu TH: Clinicopathological characteristics and prognosis of patients with small intestinal stromal tumors. J Formos Med Assoc; 2005 Dec;104(12):905-12
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  • METHODS: A total of 82 surgically resected and pathologically diagnosed smooth muscle tumors of small bowel in patients treated from January 1986 to December 2000 were included.
  • Immunohistochemical studies were performed on these tumors with antibodies of CD117, CD34, smooth muscle actin (SMA), desmin and S-100.
  • Survival analysis demonstrated that tumor size < 5 cm (p = 0.021), mitosis number < 5/50 high-power field (p < 0.001), SMA-positive (p = 0.027), non-epithelioid cell type (p = 0.005) and tumor with skeinoid fibers (p = 0.010) predicted longer disease-free survival after operation.
  • Multivariate analysis revealed that mitotic number (p = 0.001), cell morphology (p = 0.031) and tumor size (p = 0.004) were independent prognostic factors.
  • SMA reactivity is a predictor of benign clinical behavior in SISTs.
  • Tumor mitotic numbers, tumor size, and cell type were independent prognostic factors for patients with SISTs after operation.

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  • (PMID = 16607447.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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73. Al-Talib A, Tulandi T: Pathophysiology and possible iatrogenic cause of leiomyomatosis peritonealis disseminata. Gynecol Obstet Invest; 2010;69(4):239-44
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  • We present a case of leiomyomatosis peritonealis disseminata (LPD) after myoma morcellation and review the literature using the keywords leiomyomatosis peritonealis disseminata and disseminated peritoneal leiomyomatosis.
  • The possible causes could be divided into hormonal, subperitoneal mesenchymal stem cells, metaplasia, genetic, or iatrogenic after morcellation of myoma during laparoscopic surgery.
  • It appears that LPD could be due to metaplasia of mesenchymal cells of the peritoneum and, in susceptible women, leaving fragments of myoma in the abdominal cavity might contribute to the development of LPD.
  • Accordingly, one should avoid leaving fragments of the uterus or myoma tissue in the abdominal cavity after morcellation.
  • [MeSH-major] Iatrogenic Disease. Leiomyoma / surgery. Leiomyomatosis / etiology. Peritoneal Neoplasms / etiology. Uterine Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Gynecologic Surgical Procedures / adverse effects. Gynecologic Surgical Procedures / methods. Humans. Middle Aged. Myoma / surgery. Uterine Cervical Neoplasms / surgery

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  • [Copyright] Copyright (c) 2010 S. Karger AG, Basel.
  • (PMID = 20068330.001).
  • [ISSN] 1423-002X
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 74
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74. Derbent A, Turhan NO: Acute urinary retention caused by a large impacted leiomyoma. Arch Gynecol Obstet; 2009 Dec;280(6):1045-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a case of complete UR caused by impaction of a large myomatous uterus.
  • Laparotomy revealed a large myoma filling the entire pelvic cavity.

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  • (PMID = 19333612.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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75. Vlahos NF: Hysteroscopic resection of a large submucosal fibroid using intermittent bimanual uterine massage and a bipolar resectoscope: a case report. J Reprod Med; 2005 Jul;50(7):543-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hysteroscopic resection of a large submucosal fibroid using intermittent bimanual uterine massage and a bipolar resectoscope: a case report.
  • BACKGROUND: Hysteroscopic resection of large sub-mucosal myomas embedded deep in the myometrium is often unsuccessful due to absorption of large amounts of nonionic fluid that may result in water intoxication or incomplete resection of the intramural portion of the tumor, which later protrudes within the cavity.

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  • (PMID = 16130854.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isotonic Solutions; 451W47IQ8X / Sodium Chloride
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76. Matsubara T, Kusuzaki K, Matsumine A, Shintani K, Satonaka H, Uchida A: Acridine orange used for photodynamic therapy accumulates in malignant musculoskeletal tumors depending on pH gradient. Anticancer Res; 2006 Jan-Feb;26(1A):187-93
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  • BACKGROUND: Intra-operative photodynamic therapy has been applied with acridine orange (AO-PDT) to human musculoskeletal sarcomas for the past 4 years, resulting in a low local recurrence rate, within 10%, after intra-marginal tumor resection and excellent limb function.
  • However, it is still unclear why acridine orange (AO) specifically accumulates in tumor cells, especially in malignant tumor cells.
  • MATERIALS AND METHODS: Sixty-two musculoskeletal tumors, including 35 malignant and 27 benign tumors, were studied.
  • Using freshly resected tumor material, the extracellular pH (pHe) was measured and the fluorescence intensity of AO accumulated in the tumors was measured by an image analyzer after ex vivo exposure to 1.0 microg/ml AO, followed by blue excitation.
  • RESULTS: The results of the in vivo study, using human materials freshly resected at surgery, revealed that the pHe of the malignant musculoskeletal tumors was significantly lower than that of the benign tumors and normal muscles or adipose tissues and also showed that the AO fluorescence intensity of the malignant musculoskeletal tumors was significantly stronger than that of the benign tumors and normal muscles or adipose tissues.
  • [MeSH-major] Acridine Orange / pharmacokinetics. Bone Neoplasms / metabolism. Fluorescent Dyes / pharmacokinetics. Muscle Neoplasms / metabolism. Photochemotherapy / methods. Photosensitizing Agents / pharmacokinetics

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  • (PMID = 16475697.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Fluorescent Dyes; 0 / Photosensitizing Agents; F30N4O6XVV / Acridine Orange
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77. Kumar S, Sharma JB, Verma D, Gupta P, Roy KK, Malhotra N: Disseminated peritoneal leiomyomatosis: an unusual complication of laparoscopic myomectomy. Arch Gynecol Obstet; 2008 Jul;278(1):93-5
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  • The large myoma and several small peritoneal myomas were removed by a laparotomy.
  • They could be bits left after morcellation or could be parasitic myomas.

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  • (PMID = 18193441.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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78. Nikolov A, Markov D, Dimitrov A, Ivanov S, Diavolov V: [Treatment of preterm delivery with calcium channel blockers--Nifedipine]. Akush Ginekol (Sofiia); 2007;46(9):18-22
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  • Two were lost for follow up and another two cases were excluded because myoma uteri was diagnosed.

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  • (PMID = 18642559.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
  • [Chemical-registry-number] 0 / Calcium Channel Blockers; 0 / Tocolytic Agents; I9ZF7L6G2L / Nifedipine
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79. Stübinger SH, van der Horst Ch, Braun PM: [Pelvic tumors in the eyes of urologists]. Ther Umsch; 2007 Jul;64(7):395-8
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  • Benign tumors such as endometrial myoma, ovarian cyst and adenoma of the colon might lead to the development of urogenital symptoms.
  • These are the symptoms that lead to the diagnosis of the primary tumor.
  • The possibility of eradicating the tumor is then to be discussed after relieving the obstruction.
  • [MeSH-minor] Cystectomy. Cystoscopy. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Staging. Prostatectomy. Quality of Life. Urinary Bladder / pathology

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  • (PMID = 17948757.001).
  • [ISSN] 0040-5930
  • [Journal-full-title] Therapeutische Umschau. Revue thérapeutique
  • [ISO-abbreviation] Ther Umsch
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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80. Holzer A, Jirecek ST, Illievich UM, Huber J, Wenzl RJ: Laparoscopic versus open myomectomy: a double-blind study to evaluate postoperative pain. Anesth Analg; 2006 May;102(5):1480-4
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  • After stratification (myoma size, number of myomas, and surgeon), patients were randomized to either laparoscopy (n = 19) or laparotomy (n = 21) and received a standardized anesthesia and patient-controlled analgesia for 24 h after surgery.

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  • (PMID = 16632830.001).
  • [ISSN] 1526-7598
  • [Journal-full-title] Anesthesia and analgesia
  • [ISO-abbreviation] Anesth. Analg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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81. Sutter MA, Eggspuehler A, Grob D, Porchet F, Jeszenszky D, Dvorak J: Multimodal intraoperative monitoring (MIOM) during 409 lumbosacral surgical procedures in 409 patients. Eur Spine J; 2007 Nov;16 Suppl 2:S221-8
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  • [Title] Multimodal intraoperative monitoring (MIOM) during 409 lumbosacral surgical procedures in 409 patients.
  • A prospective study on 409 patients who received multimodel intraoperative monitoring (MIOM) during lumbosacral surgical procedures between March 2000 and December 2005 was carried out.
  • The objective of this study was to determine the sensitivity and specificity of MIOM techniques used to monitor conus medullaris, cauda equina and nerve root function during lumbosacral decompression surgery.
  • MIOM has increasingly become important to monitor ascending and descending pathways, giving immediate feedback information regarding any neurological deficit during the decompression and stabilisation procedure in the lumbosacral region.
  • A total of 409 consecutive patients with lumbosacral spinal stenosis with or without instability were monitored by MIOM during the entire surgical procedure.
  • The sensitivity of MIOM applied during decompression and fusion surgery of the lumbosacral region was calculated as 90%, and the specificity was calculated as 99.7%.
  • On the basis of the results of this study, MIOM is an effective method of monitoring the conus medullaris, cauda equina and nerve root function during surgery at the lumbosacral junctions and might reduce postoperative surgical-related complications and therefore improve the long-term results.
  • [MeSH-major] Lumbosacral Region / surgery. Monitoring, Intraoperative / methods. Spinal Diseases / surgery

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  • [Cites] Acta Orthop Scand. 1999 Aug;70(4):329-34 [10569260.001]
  • [Cites] Spine (Phila Pa 1976). 2000 Jun 1;25(11):1437-46 [10828927.001]
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  • (PMID = 17912559.001).
  • [ISSN] 0940-6719
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2072902
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82. Kamimura H, Mochiki E, Kamiyama Y, Aihara R, Kimura H, Kuwano H: Gastrointestinal stromal tumor of the stomach: report of a case. Hepatogastroenterology; 2005 Jul-Aug;52(64):1297-300
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  • [Title] Gastrointestinal stromal tumor of the stomach: report of a case.
  • We report herein a case of a 65-year-old woman who had a gastrointestinal stromal tumor (GIST) of the stomach.
  • Preoperative endoscopic and X-ray examinations showed a spherical submucosal tumor in the gastric fornix.
  • We resected the tumor by laparoscopic surgery, because it was detected by computed tomography (CT) and positron emission tomography (PET), and they did not detect distant metastasis.
  • Postoperative histologic examination revealed that the tumor was composed of spindle-shaped cells with elongated nuclei and showed little mitosis.
  • Almost all of the cells showed immunoreactivity for c-kit, CD34, vimentin and but did not show alpha-smooth muscle actin (SMA), S-100, or desmin.
  • The tumor did not show differentiation toward smooth muscle or neural cells.
  • Pathological findings showed this tumor was probably benign.

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  • (PMID = 16001681.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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83. Lazaarev AF, Avbalian AM, Bobrov IP, Klimachev VV, Mischenko EV: [Co-adaptation of enzymatic systems of cells and blood supply in smooth muscle tumors of the corpus uteri]. Vopr Onkol; 2008;54(5):606-10
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  • [Title] [Co-adaptation of enzymatic systems of cells and blood supply in smooth muscle tumors of the corpus uteri].
  • We investigated co-adaptation of enzymatic systems of cells using data on activity of NAD(Ph)-dependent enzymes and AgNOR proteins of vascular endothelium vis-a-vis angiogenesis in benign and malignant smooth muscle tumors of the corpus uteri.
  • SDH-regulated oxidation in the main metabolic succession of a tricarbonic acid cycle depended on blood supply and endothelial vessel proliferation (r = 0.84 and 0.92, respectively; p = 0.04).
  • Hence, metabolic profile varied in unaltered myometrium and tumor with variable cellular density and peculiar extracellular matrix.

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  • (PMID = 19069475.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Antigens, Nuclear; 0 / nucleolar organizer region associated proteins; 53-59-8 / NADP; EC 1.3.99.1 / Succinate Dehydrogenase
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84. Bisdas S, Baghi M, Wagenblast J, Vogl TJ, Thng CH, Koh TS: Gadolinium-enhanced echo-planar T2-weighted MRI of tumors in the extracranial head and neck: feasibility study and preliminary results using a distributed-parameter tracer kinetic analysis. J Magn Reson Imaging; 2008 May;27(5):963-9
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  • MATERIALS AND METHODS: A total of 16 patients with primary malignant and benign tumors in the head and neck underwent DCE-MR studies.
  • Region-of-interest (ROI) analysis was performed in the tumor sites and the adjacent normal tissue.
  • RESULTS: All perfusion values in the tumor sites were significantly different (0.000 < or = P < or = 0.01) than those in the normal muscle tissue.
  • The median perfusion values in the tumor tissue were: F = 150.5 mL/minute/100 g, v(1) = 11.0 mL/100 g, v(2) = 31.5 mL/100 g, t(0) = 4.5 seconds, t(1) = 8.0 seconds, PS = 96.0 mL/minute/100 g, and E = 32.5.

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18407543.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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85. Qi ZH, Li CF, Li ZF, Zhang K, Wang Q, Yu DX: Preliminary study of 3T 1H MR spectroscopy in bone and soft tissue tumors. Chin Med J (Engl); 2009 Jan 5;122(1):39-43
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  • MRS provides the biochemistry information that may be used to diagnose tumors or differentiate the malignant tumor from benign.
  • The objective of this study is to investigate the benign and malignant bone and soft tissue tumors by 1H-MR spectroscopy ((1)H-MRS) on a 3 Tesla MR scanner, then to assess the usefulness of (1)H-MRS in diagnosing bone and soft tissue tumors and distinguishing benign from malignant tumors.
  • METHODS: Fifty-six patients with bone and soft tissue tumors proved clinically and pathologically were examined with (1)H-MRS. (1)H-MRS was performed to study malignant musculoskeletal tumors, benign tumors and normal muscle adjacent to lesions to analyze the characteristics, and single-voxel point-resolved spectroscopy sequence was used.
  • Then according to the results, it was judged whether there existed benign or malignant tumors.
  • RESULTS: (1)H-MRS spectra style of bone and soft tissue tumors was different from that of normal muscle, and differences also existed between benign and malignant tumors.
  • Choline level in malignant tumor was markedly higher than that in benign tumors.
  • Cho/Cr in malignant tumor was higher than in benign tumor significantly (P < 0.05).
  • The true positive rate of bone and soft tissue between benign and malignant tumors was 34/36, the true negative rate was 15/18, the false positive rate was 3/18 and the false negative rate was 2/36.
  • CONCLUSIONS: The increase of Cho level measured by (1)H-MRS is related to the bone and soft tissue malignant tumor.
  • Cho/Cr in malignant tumor was higher than in benign tumor, so they will play a vital role in the diagnosis and differential diagnosis of bone and soft tissue tumors.

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  • (PMID = 19187615.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] MU72812GK0 / Creatine; N91BDP6H0X / Choline
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86. Oh SN, Rha SE, Jung SE, Lee YJ, Choi BG, Byun JY, Ku YM, Jung CK: Transitional cell tumor of the ovary: computed tomographic and magnetic resonance imaging features with pathological correlation. J Comput Assist Tomogr; 2009 Jan-Feb;33(1):106-12
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  • [Title] Transitional cell tumor of the ovary: computed tomographic and magnetic resonance imaging features with pathological correlation.
  • OBJECTIVE: To describe computed tomographic (CT) and magnetic resonance (MR) imaging findings of transitional cell tumors, including newly established transitional cell carcinoma, according to tumor type with pathological correlation.
  • METHODS: We retrospectively reviewed the CT and MR images of 22 patients with transitional cell tumors of ovary (14 benign Brenner, 2 borderline Brenner, 2 malignant Brenner, and 4 transitional cell carcinomas) for the following factors: size, location, configuration, signal intensity, staging, and accompanying ovarian tumors.
  • RESULTS: Sixteen tumors were detected on CT or MRI (8 benign, 2 borderline, and 6 malignant tumors), and the mean size of measurable tumors was 8.8 cm.
  • Benign Brenner tumors were homogeneous solid (n = 6) or unilocular cystic (n = 2).
  • The signal intensity of solid components on T2-weighted images was isointense compared with that of muscle in benign and borderline Brenner tumors and hyperintense in malignant tumors.
  • CONCLUSIONS: The CT and MR appearance of transitional cell tumors varied according to tumor type.
  • Benign Brenner tumors were homogeneous solid or unilocular cystic pattern, and malignant tumors were heterogeneous solid or multilocular cystic.

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  • (PMID = 19188796.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Lai CC, Chang CK, Wang JY: Hypertension secondary to bilateral hydronephrosis caused by a large uterine myoma. Am J Kidney Dis; 2009 Dec;54(6):1187
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  • [Title] Hypertension secondary to bilateral hydronephrosis caused by a large uterine myoma.

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  • (PMID = 19932880.001).
  • [ISSN] 1523-6838
  • [Journal-full-title] American journal of kidney diseases : the official journal of the National Kidney Foundation
  • [ISO-abbreviation] Am. J. Kidney Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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88. Marret H, Chevillot M, Giraudeau B, Study Group of the French Society of Gynaecology and Obstetrics (Ouest Division): Factors influencing laparoconversions during the learning curve of laparoscopic myomectomy. Acta Obstet Gynecol Scand; 2006;85(3):324-9
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  • BACKGROUND: To assess the probability of conversion of a laparoscopic myomectomy to an open procedure, we only found the score developed by Dubuisson et al. (2001) based on four preoperative risk factors.
  • We confirmed the importance of two of the four risk factors in Dubuisson's model: biggest myoma size at ultrasonography (increased 1 mm) (OR: 1.06) and intramural type (OR: 3.25) of the dominant myoma.


89. Cook H, Ezzati M, Segars JH, McCarthy K: The impact of uterine leiomyomas on reproductive outcomes. Minerva Ginecol; 2010 Jun;62(3):225-36
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  • Uterine leiomyomas (fibroids, myomas) are a common benign disease of the uterus with a prevalence of 8-18%.
  • In this paper we review evidence that uterine fibroids, specifically submucosal and intramural myomas, negatively impact fertility and are associated with adverse obstetrical outcomes such as: pain, preterm labor, placental abruption, malpresentation, postpartum hemorrhage, and cesarean section.
  • For women that do not desire surgery, medical management of myomas is available.

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  • (PMID = 20595947.001).
  • [ISSN] 0026-4784
  • [Journal-full-title] Minerva ginecologica
  • [ISO-abbreviation] Minerva Ginecol
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA HD008737-09
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Other-IDs] NLM/ NIHMS302135; NLM/ PMC4120295
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90. Fehlings MG, Brodke DS, Norvell DC, Dettori JR: The evidence for intraoperative neurophysiological monitoring in spine surgery: does it make a difference? Spine (Phila Pa 1976); 2010 Apr 20;35(9 Suppl):S37-46
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  • CONCLUSION: Based on strong evidence that multimodality intraoperative neuromonitoring (MIOM) is sensitive and specific for detecting intraoperative neurologic injury during spine surgery, it is recommended that the use of MIOM be considered in spine surgery where the spinal cord or nerve roots are deemed to be at risk, including procedures involving deformity correction and procedures that require the placement of instrumentation.
  • There is a need to develop evidence-based protocols to deal with intraoperative changes in MIOM and to validate these prospectively.
  • [MeSH-major] Intraoperative Complications / prevention & control. Monitoring, Intraoperative / methods. Neurosurgical Procedures / adverse effects. Spinal Cord Injuries / prevention & control. Spinal Diseases / surgery
  • [MeSH-minor] Electrodiagnosis / methods. Electrodiagnosis / standards. Evidence-Based Medicine. Humans. Iatrogenic Disease / prevention & control. Medical Errors / prevention & control. Risk Management / methods. Risk Management / standards


91. Aslam M, Ijaz L, Tariq S, Shafqat K, Meher-Un-Nisa, Ashraf R, Kazmi T: Comparison of transvaginal sonography and saline contrast sonohysterography in women with abnormal uterine bleeding: correlation with hysteroscopy and histopathology. Int J Health Sci (Qassim); 2007 Jan;1(1):17-24
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  • The presence of focal endometrial lesions and the type of lesion (endometrial hyperplasia, polyp, submucous myoma, or malignancy) were noted.
  • The diagnostic performance of sonohysterography for 3 main endometrial abnormalities (i.e. endometrial hyperplasia, polyps and submucous myoma) was better than transvaginal sonography.
  • The best results were seen in cases of submucous myoma where sensitivity and specificity of sonohysterography reached to 100% as compared to TVS (61.55 and 97.7% respectively).

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  • (PMID = 21475448.001).
  • [ISSN] 1658-3639
  • [Journal-full-title] International journal of health sciences
  • [ISO-abbreviation] Int J Health Sci (Qassim)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3068651
  • [Keywords] NOTNLM ; Ultrasound / abnormal uterine bleeding / hysteroscopy / sonohysterography / transvaginal sonography
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92. Kim HJ, Kim CH, Choi YJ, Ayala AG, Amirikachi M, Ro JY: Juxtaglomerular cell tumor of kidney with CD34 and CD117 immunoreactivity: report of 5 cases. Arch Pathol Lab Med; 2006 May;130(5):707-11
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  • [Title] Juxtaglomerular cell tumor of kidney with CD34 and CD117 immunoreactivity: report of 5 cases.
  • CONTEXT: Juxtaglomerular cell tumor is a rare renal neoplasm.
  • Renin immunohistochemistry and electron microscopic documentation of rhomboid crystals are the primary methods of diagnosing this benign tumor.
  • OBJECTIVES: In this retrospective study, we evaluated the morphologic, immunohistochemical, and ultrastructural features of 5 cases of juxtaglomerular cell tumor to determine the effectiveness of CD34 and CD117 immunohistochemistry for the diagnosis of this tumor.
  • On light microscopic examination, we found solid sheets and nests of tumor cells with oval-to-round nuclei and eosinophilic cytoplasm.
  • Immunohistochemistry results were as follows: vimentin (positive), renin (weakly positive), smooth muscle actin (focal immunoreactivity), and cytokeratin (negative).
  • CONCLUSIONS: Our findings indicate that immunohistochemistry for CD34 and CD117 are effective at diagnosing juxtaglomerular cell tumor.
  • Juxtaglomerular cell tumor should be considered in the diagnosis of any renal tumors with epithelioid cells and negative initial cytokeratin immunohistochemistry.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Female. Humans. Hypertension / diagnosis. Male. Middle Aged. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16683889.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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93. Scheller C, Richter HP, Scheuerle A, Kretschmer T, König RW, Antoniadis G: Intraneural perineuriomas; a rare entity. Clinical, surgical and neuropathological details in the management of these lesions. Zentralbl Neurochir; 2008 Aug;69(3):134-8
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  • OBJECTIVE: Perineuriomas are rare benign peripheral nerve sheath tumors, which have only been included in the WHO classification system since 2000.
  • Two of these patients had previously been treated with decompression and neurolysis of the nerve for the suspicion of a nerve compression syndrome.
  • Two of the four patients showed a partial improvement of their motor and sensorial nerve deficits in the long-term follow-up following complete tumor resection and interpositional autologous nerve grafts.
  • In cases of slow-progressive neurological deficits of a peripheral nerve in young patients the differential diagnosis should include the intraneural perineuriomas.
  • [MeSH-minor] Adult. Child, Preschool. Diagnosis, Differential. Fingers / innervation. Fingers / pathology. Fingers / surgery. Humans. Immunohistochemistry. Infant. Magnetic Resonance Imaging. Male. Muscle Weakness / etiology. Peroneal Neuropathies / etiology. Peroneal Neuropathies / pathology. Peroneal Neuropathies / surgery. Radial Neuropathy / etiology. Radial Neuropathy / pathology. Radial Neuropathy / surgery. S100 Proteins / metabolism. Treatment Outcome. Ulnar Neuropathies / etiology. Ulnar Neuropathies / pathology. Ulnar Neuropathies / surgery

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  • (PMID = 18666052.001).
  • [ISSN] 0044-4251
  • [Journal-full-title] Zentralblatt für Neurochirurgie
  • [ISO-abbreviation] Zentralbl. Neurochir.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / S100 Proteins
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94. Ellinger J, Bastian PJ, Ellinger N, Kahl P, Perabo FG, Büttner R, Müller SC, Ruecker Av: Apoptotic DNA fragments in serum of patients with muscle invasive bladder cancer: a prognostic entity. Cancer Lett; 2008 Jun 18;264(2):274-80
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  • [Title] Apoptotic DNA fragments in serum of patients with muscle invasive bladder cancer: a prognostic entity.
  • In this study, we investigated serum DNA levels in each 45 patients with bladder cancer (BCA) undergoing radical cystectomy and with benign prostate hyperplasia.
  • [MeSH-major] Apoptosis / physiology. Biomarkers, Tumor / blood. DNA / blood. DNA Fragmentation. Urinary Bladder Neoplasms / blood

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  • (PMID = 18329789.001).
  • [ISSN] 0304-3835
  • [Journal-full-title] Cancer letters
  • [ISO-abbreviation] Cancer Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 9007-49-2 / DNA
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95. Cantisani V, D'Ambrosio U, Olive M, Marsecano C, Guerrisi I, Medvedyeva E, Maldur V, Di Segni M, Malpassini F, Pepe A, Bassetti E: Vascular leiomyoma presenting as medial joint line pain of the knee. J Ultrasound; 2009 Dec;12(4):163-5
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  • Vascular leiomyoma or angioleiomyoma is a rare benign solitary smooth muscle tumor that occurs mostly in the extremities.
  • Most of these tumors are composed of venous vessels, but in some reports small arteries have been detected in the tumors.We present a rare case of a 60-year-old man with a subcutaneous vascular leiomyoma of the right knee.

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  • (PMID = 23396993.001).
  • [ISSN] 1971-3495
  • [Journal-full-title] Journal of ultrasound
  • [ISO-abbreviation] J Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3553096
  • [Keywords] NOTNLM ; MR / Subcutaneous tumors / US / Vascular leiomyoma
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96. Tamiolakis D, Chimona TS, Georgiou G, Proimos E, Nikolaidou S, Perogamvrakis G, Papadakis CE: Accessory parotid gland carcinoma ex pleomorphic adenoma. Case study diagnosed by fine needle aspiration. Stomatologija; 2009;11(1):37-40
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  • OBJECTIVE: The accessory parotid gland is salivary tissue separated from the main parotid gland and lying on masseter muscle.
  • However, the appearance of an accessory parotid tumor is rare, with a reported frequency of 1-7.7% of all parotid gland tumors.
  • Carcinoma ex pleomorphic adenoma arises from a pre-existing benign mixed tumor.
  • Reports of Fine Needle Aspiration Cytological (FNAC) diagnosis of malignant mixed tumor are uncommon and have been limited to cases arising in the parotid.
  • FNA was performed and the smears demonstrated features indicative of pleomorphic adenoma admixed with findings indicative of a poorly differentiated carcinoma.

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  • (PMID = 19423970.001).
  • [ISSN] 1392-8589
  • [Journal-full-title] Stomatologija
  • [ISO-abbreviation] Stomatologija
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lithuania
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97. Zhu HN, Yu JP, Luo J, Jiang YH, Li JQ, Sun WY: Gastric adenomyoma presenting as melena: a case report and literature review. World J Gastroenterol; 2010 Apr 21;16(15):1934-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Gastric adenomyoma (AM) is a rare benign tumor characterized by gland-like structures embedded within a smooth muscle stroma.
  • We report a case of a 68-year-old man with gastric AM admitted to our hospital for melana.
  • Histologic examination of the excised specimen showed irregularly arranged glands and interlacing smooth muscle bundles surrounding the glandular elements.
  • Although gastric AM is rare, it should be considered in differential diagnosis of extramucosal gastric tumor.
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Endoscopy / methods. Endoscopy, Gastrointestinal / methods. Humans. Microscopy / methods. Muscle, Smooth / pathology

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  • [Cites] Virchows Arch. 2000 Feb;436(2):172-4 [10755609.001]
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  • (PMID = 20397275.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 11
  • [Other-IDs] NLM/ PMC2856838
  • [Keywords] NOTNLM ; Adenomyoma / Endoscopic examination / Histopathology / Melana / Stomach
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98. Larraín D, Rabischong B, Khoo CK, Botchorishvili R, Canis M, Mage G: "Iatrogenic" parasitic myomas: unusual late complication of laparoscopic morcellation procedures. J Minim Invasive Gynecol; 2010 Nov-Dec;17(6):719-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "Iatrogenic" parasitic myomas: unusual late complication of laparoscopic morcellation procedures.
  • STUDY OBJECTIVE: To describe our experience in diagnosing and managing parasitic myomas developing as an unexpected late complication of laparoscopic morcellation.
  • DESIGN: Observational study (Canadian Task Force classification II-3).
  • PATIENTS: Retrospective chart review of all patients found to have parasitic myomas that developed after previous morcellation.
  • One patient had no symptoms, and was referred because of a suspect pelvic mass.
  • CONCLUSION: These masses probably resulted from growth of missed fragments of uterine tissue after previous morcellation, culminating in development of symptomatic iatrogenic parasitic myomas.
  • In patients with a history of morcellation who have pelvic masses, iatrogenic parasitic myomas should be considered in the differential diagnosis.

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  • [Copyright] Copyright © 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20655285.001).
  • [ISSN] 1553-4669
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Merani R, Khannah G, Mann S, Ghabrial R: Orbital leiomyoma: a case report with clinical, radiological and pathological correlation. Clin Exp Ophthalmol; 2005 Aug;33(4):408-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Orbital leiomyoma is a benign tumour of smooth muscle origin that can be clinically, radiologically and histopathologically difficult to diagnose due to the rarity of leiomyomas in this location.
  • Microscopically the lesion was a well-circumscribed tumour composed of spindle cells.
  • Leiomyoma is a tumour that is rarely found in the orbit most likely due to the paucity of smooth muscle in this location.
  • Surgical excision in this case excluded malignancy, provided a definitive diagnosis of a rare entity and resulted in marked clinical improvement.
  • [MeSH-minor] Actins / analysis. Aged. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Desmin / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Ophthalmologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16033356.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Desmin
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100. Takahashi Y, Shimizu S, Ishida T, Aita K, Toida S, Fukusato T, Mori S: Plexiform angiomyxoid myofibroblastic tumor of the stomach. Am J Surg Pathol; 2007 May;31(5):724-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plexiform angiomyxoid myofibroblastic tumor of the stomach.
  • We report 2 cases of plexiform angiomyxoid myofibroblastic tumor of the stomach, a tumor entity that has not been described previously.
  • The tumor in case 2 was incidentally found at laparoscopic cholecystectomy.
  • The tumor caused gastric perforation in case 1.
  • Bland spindle tumor cells were observed, and they were separated by abundant intercellular myxoid matrix.
  • Immunohistochemically, the tumor cells were positive for alpha-smooth muscle actin and muscle actin, and negative for KIT, CD34, and S-100 protein.
  • Electron microscopic findings were consistent with the myofibroblastic nature of the tumor cells.
  • Although clinical follow-up data were insufficient, the histologic appearances suggested the benign nature of the tumors.
  • However, the tumor in case 1 caused gastric perforation and necessitated an emergency operation.
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Cytoplasm / ultrastructure. Diagnosis, Differential. Disease-Free Survival. Gastrectomy. Humans. Immunohistochemistry. Male. Middle Aged. Treatment Outcome

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  • [CommentIn] Am J Surg Pathol. 2008 Dec;32(12):1910-2; author reply 1912-3 [18824895.001]
  • [CommentIn] Am J Surg Pathol. 2008 Dec;32(12):1910; author reply 1912-3 [18824897.001]
  • (PMID = 17460456.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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