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1. Nasser F, Affonso BB, de Jesus-Silva SG, Coelho Dde O, Zlotnik E, Messina Mde L, Baracat EC: [Uterine fibroid embolization in women with giant fibroids]. Rev Bras Ginecol Obstet; 2010 Nov;32(11):530-5
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Embolização de mioma uterino em mulheres portadoras de miomas volumosos.

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  • (PMID = 21271163.001).
  • [ISSN] 1806-9339
  • [Journal-full-title] Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
  • [ISO-abbreviation] Rev Bras Ginecol Obstet
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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2. Tchartchian G, Dietzel J, Bojahr B, Hackethal A, De Wilde RL: No more abdominal hysterectomy for myomata using a new minimally-invasive technique. Int J Surg Case Rep; 2010;1(1):7-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] No more abdominal hysterectomy for myomata using a new minimally-invasive technique.
  • For a uterine weight of >1000 g, after a caesarean section and in nullipara per vaginam, the most common surgical technique for hysterectomy in patients is hysterectomy per laparotomiam.

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  • (PMID = 22096663.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC3199612
  • [Keywords] NOTNLM ; Hysterectomy / Laparoscopy / Laparotomy / Uterus myomatosus
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3. Yoon HJ, Kyung MS, Jung US, Choi JS: Laparoscopic myomectomy for large myomas. J Korean Med Sci; 2007 Aug;22(4):706-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic myomectomy for large myomas.
  • The aim of this study was to assess the feasibility and efficacy of laparoscopic myomectomy (LM) for large myomas.
  • A subpopulation of 51 patients with myomas 8 cm or larger in diameter was selected from 155 patients who underwent LM at Kangbuk Samsung Hospital from July 2003 to November 2006.
  • The mean operating time was 85.6 +/- 38.9 min, and the mean diameter of the largest myoma was 9.3 +/- 1.8 cm.
  • With the newly-developed screw and the port placement system that was modified from the Choi's 4-trocar method to obtain better surgical vision, LM of large myomas proved to be one of the efficient and feasible methods.

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  • [Cites] Surg Technol Int. 2006;15:123-9 [17029172.001]
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  • (PMID = 17728514.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2693824
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4. Costa Benavente L, Silva Barroso F, Avila Flores E: [Giant uterine myoma]. Ginecol Obstet Mex; 2005 Oct;73(10):563-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant uterine myoma].
  • [Transliterated title] Mioma uterino gigante.
  • We report the case of a 45-year old woman with a large abdominal mass and three-day history of constipation and respiratory difficulty.
  • Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed, and a giant uterine myoma, which weighted 12.4 kg (27.3 lb), was found.

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  • (PMID = 16583838.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 7
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5. Andreani M, Vergani P, Ghidini A, Locatelli A, Ornaghi S, Pezzullo JC: Are ultrasonographic myoma characteristics associated with blood loss at delivery? Ultrasound Obstet Gynecol; 2009 Sep;34(3):322-5
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Are ultrasonographic myoma characteristics associated with blood loss at delivery?
  • OBJECTIVES: The presence of myomas in pregnancy is associated with greater blood loss at delivery.
  • The aim of this study was to evaluate whether the sonographic characteristics of myomas can predict blood loss at delivery in women with large myomas.
  • METHODS: Among women who underwent second-trimester ultrasound screening at our department between January 1996 and December 2004, 251 had at least one myoma with a mean diameter > or = 5 cm.
  • Number of myomas (single vs. multiple), maximum diameter of the largest myoma, sum of the maximum diameter of each myoma, change in size of myomas between first and last scan, and location in relation to the placenta and to the presenting part of the fetus (above or below) were analyzed in relation to blood loss at delivery and severe postpartum hemorrhage (> or = 1000 mL).
  • RESULTS: Multivariate analysis showed that the presence of multiple myomas was the only parameter independently associated with amount of blood loss at delivery (P = 0.003).
  • The association between the presence of multiple myomas and severe postpartum hemorrhage was of borderline significance for the statistical power of this study (P = 0.08).
  • CONCLUSIONS: In women with large myomas, the presence of multiple tumors is independently associated with heavier blood loss at delivery but not with postpartum hemorrhage of > or = 1000 mL.

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  • (PMID = 19670350.001).
  • [ISSN] 1469-0705
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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6. Vázquez Camacho EE, Cabrera Carranco E, Sánchez Herrera RG: [Pedunculated twisted myoma and pregnancy. Case report]. Ginecol Obstet Mex; 2009 Sep;77(9):441-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pedunculated twisted myoma and pregnancy. Case report].
  • [Transliterated title] Mioma pediculado torcido en una mujer embarazada. Reporte de caso.
  • The detection of a pelvic mass during pregnancy is uncommon.
  • We report a case of a woman at the 15 week of gestation with torsi6n of a pedunculated mioma mimicking in the ultrasonografic image an ovarian tumor.

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  • (PMID = 19899435.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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7. Damiani A, Melgrati L, Marziali M, Sesti F, Piccione E: Laparoscopic myomectomy for very large myomas using an isobaric (gasless) technique. JSLS; 2005 Oct-Dec;9(4):434-8
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic myomectomy for very large myomas using an isobaric (gasless) technique.
  • OBJECTIVES: Laparoscopic myomectomy using pneumoperitoneum for large myomas (> or = 8 cm) is hindered by several factors, such as the increased operative time, the risk of perioperative bleeding, and the risk of conversion to laparotomy.
  • The aim of this study was to evaluate the feasibility, reproducibility, and safety of isobaric laparoscopic myomectomy for very large myomas > or = 10 cm using a subcutaneous abdominal wall-lifting device.
  • METHODS: A series of 24 consecutive patients with at least 1 symptomatic myoma > or = 10 cm underwent a gasless laparoscopic myomectomy with the Laparotenser device.
  • The size of the dominant myoma varied from 10 cm to 20 cm.
  • CONCLUSION: Gasless laparoscopic myomectomy is feasible, reproducible, and safe for removing very large myomas.
  • Therefore, it can represent an excellent option for the minimally invasive removal of very large myomas.

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  • (PMID = 16381362.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015631
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8. Hrgović Z, Kulas T, Habek D, Izetbegović S, Hrgović I: [New options in the diagnosis and management of uterine myoma]. Med Arh; 2008;62(4):234-9
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [New options in the diagnosis and management of uterine myoma].
  • [Transliterated title] Nove mogućnosti u dijagnostici i lijecenju mioma maternice.
  • Myoma accounts for nearly 95% of all benign tumors of female genital organs and is the most common neoplasm of female genital tract.
  • Along with thorough history and gynecologic examination, ultrasound study is of utmost importance in the diagnosis of myoma; magnetic resonance (MR) study may also be required in rare cases.
  • A number of therapeutic options are available for the management of myoma, ranging from medicamentous therapy through operative procedures (e.g., total or supracervical hysterectomy or myoma enucleation) and novel non-operative procedures (e.g., embolization of uterine artery (EUA) and magnetic resonance guided focused ultrasound (MRgFUS).
  • Discomforts caused by a myoma are an absolute indication for treatment.
  • Therapeutic option to be chosen is determined by the number, size and location of myomas, and the patient's preferences.

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  • (PMID = 19145810.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Bosnia and Herzegovina
  • [Number-of-references] 61
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9. Pérez-Cejudo JA, Piqué E, Arduan I, Palacios S, Sánchez C, Rodríguez M, Morales R: [Umbilical cutaneous endometriosis associated with a large uterine myoma]. Actas Dermosifiliogr; 2005 Jan-Feb;96(1):43-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Umbilical cutaneous endometriosis associated with a large uterine myoma].
  • [Transliterated title] Endometriosis cutánea umbilical asociada a mioma uterino gigante.
  • The Dermatology Department was consulted because of an asymptomatic umbilical tumor which had been developing for 5 years.
  • [MeSH-major] Endometriosis / complications. Leiomyoma / complications. Skin Diseases / complications. Umbilicus. Uterine Neoplasms / complications


10. Squillaci S, Cecchetti D, Tallarigo F, Pontieri F, Filardo AV: [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature]. Pathologica; 2005 Dec;97(6):378-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature].
  • [Transliterated title] Mioma perivascolare di tipo miopericitoma dei tessuti molli del piede: descrizione di un caso e revisione della letteratura.
  • We describe a rare case of myopericytoma-type perivascular myoma (MTPM) which arose in acral location and the literature on this field is briefly reviewed.
  • Immunohistochemically, the neoplastic cells were positive for vimentin, smooth muscle actin, desmin and calponin, negative for S-100 protein, CD34, CD31 and cytokeratins (AE1/AE3, Cam 5.2).
  • [MeSH-major] Foot Diseases / pathology. Myoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16619980.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 16
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11. Palmara V, Triolo O, Benedetto V, Lo Re C, Sturlese E, Retto G, Santoro G: Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate. Gynecol Obstet Invest; 2010;69(2):131-5
Hazardous Substances Data Bank. LEUPROLIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate.
  • AIM: We studied morphologic modifications of the endometrium induced by leuprorelin acetate, a gonadotropin-releasing hormone agonist, in women with uterine myomata.
  • RESULTS: A near-normal endometrium was observed after 2 months of therapy, while treatment with 6 cycles of leuprorelin acetate induced a uniform morphologic regression of the uterine mucosa.


12. Asciutto G, Mumme A, Marpe B, Hummel T, Asciutto KC, Geier B: Deep venous thrombosis in a patient with large uterine myomata. Case report. Minerva Ginecol; 2008 Oct;60(5):451-3
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep venous thrombosis in a patient with large uterine myomata. Case report.
  • Computed tomography revealed an inhomogenous uterine enlargement due to multiple myomata producing a thrombotic occlusion of the left iliac veins.
  • Uterine myomata rarely cause acute iliac vein thrombosis due to direct compression.


13. Parker WH: Uterine myomas: management. Fertil Steril; 2007 Aug;88(2):255-71
Hazardous Substances Data Bank. PROGESTERONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine myomas: management.
  • OBJECTIVE: To review the currently available literature regarding the current management alternatives available to women with uterine myomas.
  • DESIGN: Literature review of 198 articles pertaining to uterine myomas.
  • RESULT(S): Many advances have been made in the management of uterine myomas.
  • CONCLUSION(S): Many options are now available to women with uterine myomas.
  • The presently available literature regarding the treatment of myomas is summarized.
  • [MeSH-major] Myoma / therapy. Uterine Neoplasms / therapy

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  • (PMID = 17658523.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 33515-09-2 / Gonadotropin-Releasing Hormone; 4G7DS2Q64Y / Progesterone
  • [Number-of-references] 141
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14. McLucas B, Chespak L, Kaminsky D: Myoma necrosis following Gelfoam embolization of uterine myomata. Minim Invasive Ther Allied Technol; 2008;17(3):200-4
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myoma necrosis following Gelfoam embolization of uterine myomata.

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  • (PMID = 18666018.001).
  • [ISSN] 1365-2931
  • [Journal-full-title] Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
  • [ISO-abbreviation] Minim Invasive Ther Allied Technol
  • [Language] eng
  • [Publication-type] Comparative Study; Controlled Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemostatics
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15. Dilek S, Ertunc D, Tok EC, Cimen R, Doruk A: The effect of myomectomy on health-related quality of life of women with myoma uteri. J Obstet Gynaecol Res; 2010 Apr;36(2):364-9
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The effect of myomectomy on health-related quality of life of women with myoma uteri.
  • Many studies have evaluated the effect of other methods rather than myomectomy on HRQoL, and have focused solely on the presence of myoma without regarding any concurrent pelvic pathology.
  • METHODS: This study involved 80 patients with myomas and 75 controls.
  • Domains of the Short Form - 36 (SF-36) questionnaire were evaluated pre- and postoperatively in 72 women with myomas.
  • Furthermore, any correlations between myoma characteristics and SF-36 physical components (PC) and mental components (MC) were investigated.
  • RESULTS: All SF-36 domains were lower in women with myoma uteri than in the control group, except for physical and social function.
  • There was no correlation between PC and MC scores and the number, location and total volume of the myomas.
  • However, fundal and posteriorly positioned myomas were related with the PC score, and posterior myomas with the MC score.
  • CONCLUSION: The findings from this study suggest that myomectomy improves HRQoL, and that myoma characteristics may modulate quality of life domains.

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  • (PMID = 20492389.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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16. Markowska A, Rucinski M, Drews K, Malendowicz LK: Further studies on leptin and leptin receptor expression in myometrium and uterine myomas. Eur J Gynaecol Oncol; 2005;26(5):517-25
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Further studies on leptin and leptin receptor expression in myometrium and uterine myomas.
  • AIM: Examination of the potential role of leptin in the development of uterine myomas.
  • Expression of the leptin gene and leptin receptor gene was tested in the myometrium of healthy women, and in myomas and the surrounding myometrium of women with benign tumors.
  • METHODS: Using RT-PCR, expression of the leptin gene and leptin receptor gene were studied in myomas and in the surrounding myometrium in 30 women with uterine myomas at various phases of the menstrual cycle, and in the myometrium of ten women in a control group.
  • RESULTS: Using RT-PCR, expression of the leptin gene was demonstrated both in myomas and in the surrounding myometrium.
  • CONCLUSION: Demonstration of the expression of leptin genes and leptin proteins in uterine myomas and in the surrounding myometrium, and their absence in the myometrium of healthy women suggests the involvement of leptin in the development of uterine myomas.

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  • (PMID = 16285570.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Leptin; 0 / Receptors, Cell Surface; 0 / Receptors, Leptin; 0 / leptin receptor, human
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17. Nezhat C, Kho K: Iatrogenic myomas: new class of myomas? J Minim Invasive Gynecol; 2010 Sep-Oct;17(5):544-50
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Iatrogenic myomas: new class of myomas?
  • Parasitic myomas, defined as extrauterine seeding of leiomyoma, have been reported since the early 1900s.
  • These myomas were thought to be spontaneously occuring, separate from the uterus but still hormone-dependent and can cause symptoms.
  • What seemed to be a rare disorder developing from the natural history of pedunculated myomas has become increasingly reported over the last decade.
  • Because it is still a rare disorder, the literature is limited to case reports.
  • [MeSH-major] Gynecologic Surgical Procedures / adverse effects. Leiomyoma / surgery. Neoplasm Seeding. Uterine Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Iatrogenic Disease. Middle Aged

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  • [Copyright] Copyright © 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20580324.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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18. Nappi L, Matteo M, Giardina S, Rosenberg P, Indraccolo U, Greco P: Management of uterine giant myoma. Arch Gynecol Obstet; 2008 Jul;278(1):61-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of uterine giant myoma.
  • BACKGROUND: Giant myomas of the uterus are uncommon, particularly in developed countries.
  • CASE: This report illustrates a case of a woman with a bilobated giant myoma of the uterus weighed in total 27.7 kg.
  • CONCLUSIONS: The knowledge of the different clinical manifestation of these myomas may allow to face that with adequate perioperative care, in order to assure a carefully and successfully surgery, although sometimes a benign pathology may be not easy to suspect in a first time.

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  • (PMID = 18066710.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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19. Bosev D, Dimitrov A: [Changes in uterine myoma dimentions during pregnancy]. Akush Ginekol (Sofiia); 2007;46(5):3-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Changes in uterine myoma dimentions during pregnancy].
  • The purpose of this study is to follow up the changes in the myoma dimentions during pregnancy (1st, 2nd and 3rd trimester).
  • The study is prospective and includes 90 pregnant women with myoma during the period 2002-2006.
  • If more than one myoma was diagnosed, the largest one was considered to be representative.
  • Our data show that the combination of myoma and pregnancy is more frequent with women over the age of 30 and it is more frequent with nullipares (63.2%).
  • Single myomas were more frequent with 58%, 48% of the myomas were intramural and 62% were located in the uterine corpus.
  • Our study shows that during the first trimester there is no change in the myomas dimentions in 35%-43% of the cases and during the second trimester there is no change of the myona dimentions in 50% of the cases.
  • During the third trimester there are only 5% of the myomas that change their dimentions.
  • We conclude, that the myomas, that enlarge during the first trimester, usually enlarge during the second trimester as well.
  • We found no decrease of the myoma dimentions during the third trimester.

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  • (PMID = 17974174.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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20. Miller CE: Unmet therapeutic needs for uterine myomas. J Minim Invasive Gynecol; 2009 Jan-Feb;16(1):11-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unmet therapeutic needs for uterine myomas.
  • Uterine myomas may develop in many women, but only become clinically significant in about one third of the affected population.
  • Although uterine myomas are most often benign, they are associated with debilitating symptoms and commonly result in hysterectomy.
  • Current treatments for uterine myomas include pharmacologic therapies, delivery of focused energy, alteration of uterine vascular supply, or surgical procedures.
  • Factors such as the woman's desire for future pregnancy, the importance of uterine preservation, symptom severity, and tumor characteristics direct the choice of therapeutic approach.
  • The ideal treatment will have the following characteristics: easy to perform, minimally invasive, cost effective, preserves fertility, preserves the uterus, efficacious, acceptable tolerability and durability, and low incidence of myoma recurrence.

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  • (PMID = 19110181.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 110
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21. Practice Committee of American Society for Reproductive Medicine in collaboration with Society of Reproductive Surgeons: Myomas and reproductive function. Fertil Steril; 2008 Nov;90(5 Suppl):S125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myomas and reproductive function.
  • The purpose of this Educational Bulletin is to examine the relationship between myomas and reproductive function and to review current methods for their management.
  • [MeSH-major] Myoma / physiopathology. Reproduction / physiology. Uterine Neoplasms / physiopathology

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  • (PMID = 19007608.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 33515-09-2 / Gonadotropin-Releasing Hormone
  • [Number-of-references] 72
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22. Khan KN, Kitajima M, Hiraki K, Fujishita A, Nakashima M, Ishimaru T, Masuzaki H: Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma. Hum Reprod; 2010 Nov;25(11):2878-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma.
  • BACKGROUND: We recently demonstrated the effect of gonadotrophin-releasing hormone agonist (GnRHa) on tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma.
  • Here, we investigated expression of GnRH receptors (GnRHRs) and effect of GnRHa on the proliferation of cells derived from endometria and pathological lesions of women with these reproductive diseases.
  • METHODS: Biopsy specimens were collected from lesions and corresponding endometria of 35 women with pelvic endometriosis, 45 women with ovarian endometrioma, 35 women with adenomyosis and 56 women with uterine myoma during laparoscopy or laparotomy.
  • RESULTS: Types I and II GnRHRs mRNA and proteins were expressed in eutopic endometria and pathological lesions derived from women with endometriosis, adenomyosis and uterine myoma.
  • CONCLUSIONS: Local tissue expression of GnRHR was detected in endometriosis, adenomyosis and uterine myoma.
  • In addition to a hypo-estrogenic effect, a direct anti-proliferative effect of GnRHa may be involved in the regression of these reproductive diseases with consequent remission of clinical symptoms.


23. Lee WL, Liu WM, Fuh JL, Tsai YC, Shih CC, Wang PH: Use of uterine vessel occlusion in the management of uterine myomas: two different approaches. Fertil Steril; 2010 Oct;94(5):1875-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of uterine vessel occlusion in the management of uterine myomas: two different approaches.
  • OBJECTIVE: To evaluate the difference between uterine artery occlusion alone (UAO) and combined (UVO) with simultaneous blockage of anastomosis between the uterine and ovarian vessels in the management of women with myomas in a 3-year follow-up.
  • This finding is worthy of further investigation.
  • [MeSH-major] Gynecologic Surgical Procedures / methods. Myoma / surgery. Uterine Artery / surgery. Uterine Neoplasms / surgery. Vascular Surgical Procedures / methods

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20045514.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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24. Zhu Y, Cheng Zp, Dai H, Hu Lp: The relationship between urokinase plasminogen activator/plasminogen activator inhibitor type-1 expression in myoma/myometrium and mechanism of uterine artery occlusion by laparoscopy for uterine myoma treatment. Blood Coagul Fibrinolysis; 2009 Oct;20(7):565-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The relationship between urokinase plasminogen activator/plasminogen activator inhibitor type-1 expression in myoma/myometrium and mechanism of uterine artery occlusion by laparoscopy for uterine myoma treatment.
  • The objective of the study was to investigate the pattern of expression of plasminogen activator/plasminogen activator inhibitor (PAI) system between myoma and myometrium and its correlation between outcome and laparoscopic uterine artery occlusion prior to myomectomy in the treatment of myoma. mRNA expression of PAI type-1 (PAI-1) and urokinase plasminogen activator (uPA) was detected with real-time PCR in the myoma and myometrium cells primary cultured in vitro, and uPA and PAI-I protein expression was detected with cellular immunity histochemistry.
  • First, the expression of uPA mRNA was 0.123 +/- 0.189 in myoma, which was significantly lower than 0.331 +/- 0.306 in myometrium (P < 0.05); however, the expression of PAI-I mRNA was 0.091 +/- 0.036 in myoma, which was significantly higher than 0.016 +/- 0.020 in myometrium (P < 0.05).
  • Second, the expression of uPA protein was 8.805 +/- 1.645 in myoma cells, which was lower than 22.173 +/- 4.381 in myometrium (P < 0.05); the expression of PAI-I protein was 44.765 +/- 1.090 in myoma cells, which was significantly higher than 35.928 +/- 5.351 in myometrium (P < 0.05).
  • The distinct expression pattern of uPA/PAI in myoma and myometrium might be correlated to the low recurrence rate after uterine artery occlusion prior to myomectomy in the treatment of myoma.
  • [MeSH-major] Gene Expression Regulation, Neoplastic. Myoma / metabolism. Myoma / surgery. Myometrium / metabolism. Plasminogen Activator Inhibitor 1 / genetics. Urokinase-Type Plasminogen Activator / genetics. Uterine Artery / surgery. Uterus / pathology

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  • (PMID = 19593113.001).
  • [ISSN] 1473-5733
  • [Journal-full-title] Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
  • [ISO-abbreviation] Blood Coagul. Fibrinolysis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Plasminogen Activator Inhibitor 1; 0 / RNA, Messenger; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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25. Cicinelli E, Tinelli R, Colafiglio G, Saliani N: Laparoscopy vs minilaparotomy in women with symptomatic uterine myomas: a prospective randomized study. J Minim Invasive Gynecol; 2009 Jul-Aug;16(4):422-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopy vs minilaparotomy in women with symptomatic uterine myomas: a prospective randomized study.
  • OBJECTIVE: To compare outcomes in patients with symptomatic uterine myomas who underwent laparoscopic (LPS) or minilaparotomic (MLPT) myomectomy.
  • DESIGN: Prospective randomized study (Canadian Task Force classification II-2).
  • PATIENTS: Eighty patients with no more than 3 uterine myomas of maximal diameter of 7 cm.
  • CONCLUSION: Laparoscopic myomectomy is a suitable alternative to MLPT in women with 1 to 3 myomas.
  • However, preoperative careful evaluation of the size and sites of the myomas is necessary to avert conversion and prevent complications.

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  • (PMID = 19573818.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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26. McLucas B: Repeat uterine artery embolization following technical failure. Minim Invasive Ther Allied Technol; 2009;18(2):78-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients undergoing embolization for symptomatic uterine myomata between 1997 and 2007 were included in the study.
  • Success was defined as relief of symptoms based on pre- and post-procedure questionnaires, and/or > 30% shrinkage of the largest myoma.
  • Eleven patients underwent post-embolization imaging; seven (63.6%) had successful shrinkage of the largest myoma.
  • Three patients underwent post-embolization magnetic resonance imaging evaluation; none demonstrated enhancement of myomata.
  • Of the 582 patients with imaging data, 376 (64.6%) had successful shrinkage of the largest myoma.

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  • (PMID = 19418348.001).
  • [ISSN] 1365-2931
  • [Journal-full-title] Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
  • [ISO-abbreviation] Minim Invasive Ther Allied Technol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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27. Malzoni M, Tinelli R, Cosentino F, Iuzzolino D, Surico D, Reich H: Laparoscopy versus minilaparotomy in women with symptomatic uterine myomas: short-term and fertility results. Fertil Steril; 2010 May 1;93(7):2368-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopy versus minilaparotomy in women with symptomatic uterine myomas: short-term and fertility results.
  • OBJECTIVE: To retrospectively compare the feasibility, safety, morbidity, and pregnancy outcome of laparoscopy (LPS) and minilaparotomy (LPT) in the treatment of symptomatic uterine myomas.
  • PATIENT(S): 680 nonconsecutive patients with symptomatic uterine myomas.

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  • [Copyright] Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19285666.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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28. Hald K, Kløw NE, Qvigstad E, Istre O: Treatment of uterine myomas with transvaginal uterine artery occlusion: possibilities and limitations. J Minim Invasive Gynecol; 2008 Sep-Oct;15(5):631-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of uterine myomas with transvaginal uterine artery occlusion: possibilities and limitations.
  • The objective of this pilot study was to evaluate the feasibility of a transvaginal clamp prototype used for temporary uterine artery occlusion as a treatment for myomas.
  • Ten premenopausal women aged 34 to 37 years with menorrhagia and myomas were treated with a temporary uterine artery occlusion for 6 hours.
  • Difficulties with application of the vaginal clamp were related to initial learning and size of the myomas.
  • Our initial experience shows that the treatment is feasible in some patients with symptomatic myomas.

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  • (PMID = 18722975.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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29. Szyłło K, Kulig B, Kaczmarek P, Włodarczyk B, Górski J: [Laparoscopic dissection of uterine artery and coagulation utero-ovarian ligament for the treatment of symptomatic myomas]. Ginekol Pol; 2007 Dec;78(12):944-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Laparoscopic dissection of uterine artery and coagulation utero-ovarian ligament for the treatment of symptomatic myomas].
  • OBJECTIVES: Our purpose was to evaluate the effects and safety of laparoscopic dissection of the uterine artery and coagulation of the utero-ovarian ligament in treating symptomatic myomas.
  • CONCLUSIONS: Laparoscopic dissection of the uterine artery and coagulation of the utero-ovarian ligament is a safe and effective method of treating symptomatic myomas.

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  • (PMID = 18411917.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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30. Parker WH, Iacampo K, Long T: Uterine rupture after laparoscopic removal of a pedunculated myoma. J Minim Invasive Gynecol; 2007 May-Jun;14(3):362-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine rupture after laparoscopic removal of a pedunculated myoma.
  • A patient conceived 7 years after undergoing a routine laparoscopic myomectomy of an 11-cm pedunculated myoma.

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  • (PMID = 17478371.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Takeuchi H, Kitade M, Kikuchi I, Shimanuki H, Kumakiri J, Kobayashi Y, Kobori H, Kinoshita K: A new enucleation method for cervical myoma via laparoscopy. J Minim Invasive Gynecol; 2006 Jul-Aug;13(4):334-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A new enucleation method for cervical myoma via laparoscopy.
  • A new method was used which enucleated the cervical myoma from postcervical medial incision.
  • [MeSH-major] Gynecologic Surgical Procedures / methods. Myoma / surgery. Uterine Cervical Neoplasms / surgery

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  • (PMID = 16825077.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Akaeda T, Isaka K, Nakaji T, Kakizaki D, Abe K: Clinical application of virtual hysteroscopy by CO(2)-multidetector-row computed tomography to submucosal myomas. J Minim Invasive Gynecol; 2005 May-Jun;12(3):261-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical application of virtual hysteroscopy by CO(2)-multidetector-row computed tomography to submucosal myomas.
  • STUDY OBJECTIVE: We produced virtual hysteroscopy (VH) images from the images obtained after expanding the uterine cavity of patients with submucosal myomas and performing multidetector-row computed tomography scans, and assessed them in comparison with hysteroscopic imaging and in relation to the advantages of VH.
  • DESIGN: Cohort-control study (Canadian Task Force classification II-2).
  • PATIENTS: Thirty-one patients with submucosal myomas treated by endoscopic surgery.
  • The sites of origin of the submucosal myomas were clearly visualized; their imaging was consistent with imaging by hysteroscopy; and as a method of establishing the orientation of the uterine cavity, it was possible to obtain a greater amount of information than by hysteroscopy.

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  • (PMID = 15922985.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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33. Tintara H, Aiyarak P, Mitarnun W, Geater A: Assessment of the physical properties of laparoscopic myoma-fixation devices. Surg Endosc; 2005 Feb;19(2):240-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of the physical properties of laparoscopic myoma-fixation devices.
  • BACKGROUND: The physical properties of three commercial 5-mm myoma-fixation devices available for clinical use (short-pitch corkscrew, long-pitch corkscrew, buttress-thread screw) and a standard wood screw were examined.
  • The myoma tissue at each traction site was evaluated histologically to determine its density.
  • The maximal traction forces in each myoma density group were compared using a generalized estimating equations approach to linear regression based on repeated measures within each myoma.
  • The mean maximum traction force provided by the short-pitch corkscrew (159.2 +/- 12.2 N) was significantly higher (p < 0.01) than that of the other devices in medium-density myomas, and not significantly lower than that of other devices in low-density myomas.
  • The mean maximum traction force provided by the buttress-thread screw was significantly lower than that of the short-pitch corkscrew only in medium density myomas, and did not differ significantly from that of the wood screw in any density group.
  • CONCLUSIONS: Screw-type myoma-fixation devices can provide comparable traction force with high bending strength.

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  • (PMID = 15870964.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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34. Ghezzi F, Cromi A, Bergamini V, Scarperi S, Bolis P, Franchi M: Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas. Surg Endosc; 2007 Nov;21(11):2081-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas.
  • BACKGROUND: Over the past decade an increasing demand for uterine-sparing treatment to manage symptomatic uterine myomas has become apparent in women's health care.
  • The purpose of this study was to evaluate the midterm outcomes of radiofrequency ablation (RFA) of uterine myomas in terms of durability of symptom control and level of health-related quality of life.
  • METHODS: Consecutive women with symptomatic uterine myomas, no plans for future pregnancy, and who declined hysterectomy were offered RFA ablation of uterine fibroids under laparoscopic guidance.
  • Improvement in myoma-related symptoms and impact on quality of life were assessed using a validated questionnaire (UFS-QOL).
  • RESULTS: The median number of myomas treated per patient was 1 (range = 1-3).
  • The median baseline volume of the dominant myoma was 76.8 cm3 (range = 14.8-332.8).
  • The median reduction in myoma volume was 68.8% and 77.9% at six months and one year, respectively.

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  • [Cites] Hum Reprod. 1995 Jul;10 (7):1795-6 [8582982.001]
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  • (PMID = 17514400.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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35. Daneliia GS, Paĭlodze MV, Dgebuadze MA, Matitashvili SG: [Morpho-functional parameters of the corpus luteum in healthy women and in patients of reproductive age with uterine myoma]. Morfologiia; 2006;129(1):76-80
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  • [Title] [Morpho-functional parameters of the corpus luteum in healthy women and in patients of reproductive age with uterine myoma].
  • Ovarian corpus luteum of menstruation at the stage of its peak activity was studied in normal women and in patients with proliferative uterine myoma using ultrasonography (intravaginal color Doppler imaging), laboratory analyses (progesterone and estrogen concentrations in peripheral blood) and morphological (histological, histochemical and morphometric) methods.
  • In patients with proliferative uterine myoma, the defective corpus luteum was detected, as indicated by the prevalence of small granulosa lutein cells, insignificant amount and uneven distribution of lipid inclusions in their cytoplasm, marked reduction of progesterone concentration in peripheral blood, unechogenicity, low degree of vascularization and increase in the value of resistance index of ovarian stromal arteries.

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  • (PMID = 17201326.001).
  • [ISSN] 1026-3543
  • [Journal-full-title] Morfologii︠a︡ (Saint Petersburg, Russia)
  • [ISO-abbreviation] Morfologiia
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 4G7DS2Q64Y / Progesterone
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36. Jansen FW, de Kroon CD, van Dongen H, Grooters C, Louwé L, Trimbos-Kemper T: Diagnostic hysteroscopy and saline infusion sonography: prediction of intrauterine polyps and myomas. J Minim Invasive Gynecol; 2006 Jul-Aug;13(4):320-4
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  • [Title] Diagnostic hysteroscopy and saline infusion sonography: prediction of intrauterine polyps and myomas.
  • STUDY OBJECTIVE: To compare the positive predictive value (PPV) of diagnostic hysteroscopy (DH) and saline infusion sonography (SIS) for the detection of myomas and polyps in patients with abnormal uterine bleeding.
  • DESIGN: All consecutive women referred to our University Hospital diagnosed with an intrauterine polyp or myoma by office DH or SIS were included in the study.
  • After hysteroscopic removal in an inpatient setting, histopathologic results were used as a gold standard to calculate PPV of SIS and DH. (Canadian Task Force classification II-3) SETTING: Tertiary referral center.
  • PATIENTS: Women in whom an intrauterine polyp or myoma was diagnosed either by DH or SIS MEASUREMENTS AND MAIN RESULTS: The PPVs of SIS and DH in the evaluation of intrauterine polyps and fibroids did not significantly differ.
  • CONCLUSIONS: Diagnostic hysteroscopy and saline infusion sonography are equivalent diagnostic tools for the detection of intrauterine myomas and polyps.

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  • (PMID = 16825074.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
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37. Kulishova TV, Tabashnikova NA, Akker LV: [Efficacy of general magnetotherapy in conservative therapy of uterine myoma in women of reproductive age]. Vopr Kurortol Fizioter Lech Fiz Kult; 2005 Jan-Feb;(1):26-8
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  • [Title] [Efficacy of general magnetotherapy in conservative therapy of uterine myoma in women of reproductive age].
  • Sixty women of the reproductive age with uterine myoma were divided into two groups.
  • Ultrasound investigation registered a reduction in the size of myoma nodes by 16.7% in the study group, while in the controls myoma size did not change (p < 0.05).
  • 1-year follow-up data for the study group demonstrated no cases of the myoma growth while 16.6% of the controls showed growth of myoma nodes, in 6.6% of them supravaginal myoma amputation was made for rapidly growing myoma.

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  • (PMID = 15759473.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia
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38. Demirci F, Somunkiran A, Safak AA, Ozdemir I, Demirci E: Vaginal removal of prolapsed pedunculated submucosal myoma during pregnancy. Adv Ther; 2007 Jul-Aug;24(4):903-6
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  • [Title] Vaginal removal of prolapsed pedunculated submucosal myoma during pregnancy.
  • Pedunculated submucosal myomas are generally associated with infertility and are most often encountered during the preconception period.
  • This report describes a 38-y-old pregnant woman in whom a pedunculated submucosal myoma resulted in preterm labor and was successfully removed vaginally at 26 wk gestation.

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  • (PMID = 17901039.001).
  • [ISSN] 0741-238X
  • [Journal-full-title] Advances in therapy
  • [ISO-abbreviation] Adv Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Kanaoka Y, Yoshida C, Fukuda T, Kajitani K, Ishiko O: Transcervical microwave myolysis for uterine myomas assisted by transvaginal ultrasonic guidance. J Obstet Gynaecol Res; 2009 Feb;35(1):145-51
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  • [Title] Transcervical microwave myolysis for uterine myomas assisted by transvaginal ultrasonic guidance.
  • AIM: The effects of transcervical microwave myolysis at 2.45 GHz after microwave endometrial ablation for menorrhagia were examined in patients with myomas.
  • Ten patients waiting for microwave endometrial ablation for menorrhagia caused by myomas entered the study after complete informed consent was obtained.
  • Shrinkage of the myoma was measured at 3 months and > or =6 months after the operation.
  • RESULTS: In nine patients with typical myomas, the major part consisting of a submucous or an intramural node 4.0-7.5 cm in size was necrotized.
  • The typical myomas had shrunk by 41-68% at 3 months and 37-69% at > or =6 months after the operation.
  • CONCLUSIONS: Typical myomas shrink after microwave myolysis following microwave endometrial ablation.
  • Transcervical microwave myolysis seems to be applicable as a low-invasive treatment for a typical myoma.

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  • (PMID = 19215562.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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40. Parker WH: Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril; 2007 Apr;87(4):725-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Etiology, symptomatology, and diagnosis of uterine myomas.
  • OBJECTIVE: To review the currently available literature regarding the biology, etiology, symptoms, and diagnosis of uterine myomas.
  • DESIGN: Literature review of 220 articles pertaining to uterine myomas.
  • RESULT(S): Although uterine myomas presently are not well understood, many advances have been made in the understanding of the hormonal factors, genetic factors, growth factors, and molecular biology of these benign tumors.
  • When needed, the position of myomas can be best imaged by sonohysterography or magnetic resonance imaging.
  • Evidence suggests that only submucous myomas appear to interfere with fertility, and only very rarely do myomas effect pregnancy outcome.
  • CONCLUSION(S): A summary of the available literature regarding the biology, etiology, symptomatology, and diagnosis of myomas shows that, although they are still not well understood, much has been learned about uterine myomas.
  • [MeSH-major] Myoma / etiology. Uterine Neoplasms / etiology

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  • (PMID = 17430732.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Estrogens; 0 / Growth Substances; 4G7DS2Q64Y / Progesterone
  • [Number-of-references] 98
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41. Paĭlodze MV, Kintraia PIa, Matitashvili SG, Nanikashvili DD, Rokotianskaia LA: [The morpho-functional changes of the follicular apparatus and yellow body of the ovary in women of the reproductive age with myoma]. Georgian Med News; 2006 Oct;(139):54-6
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  • [Title] [The morpho-functional changes of the follicular apparatus and yellow body of the ovary in women of the reproductive age with myoma].
  • It have been studied the morpho-functional changes of the ovaries in women of reproductive age with proliferative myoma of uteri.
  • Based on the analysis of the result of the investigation on the myomatic knots of the women in the condition of high activity of proliferation of myocytes a very complexes, multifactorial pathogenetic mechanisms of the myoma has been outlined.
  • Switch in the common changes in the dynamic oxidative stress and hyperestrogenemia promotes development of the myoma.
  • [MeSH-major] Luteal Cells / pathology. Myoma / pathology. Ovarian Follicle / pathology. Uterine Neoplasms / pathology

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  • (PMID = 17077468.001).
  • [ISSN] 1512-0112
  • [Journal-full-title] Georgian medical news
  • [ISO-abbreviation] Georgian Med News
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Georgia (Republic)
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42. Hurst BS, Matthews ML, Marshburn PB: Laparoscopic myomectomy for symptomatic uterine myomas. Fertil Steril; 2005 Jan;83(1):1-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic myomectomy for symptomatic uterine myomas.
  • OBJECTIVE: To evaluate the safety, efficacy, and techniques of laparoscopic myomectomy as treatment for symptomatic uterine myomas.
  • Improvements in surgical instruments and techniques allows for safe removal and multilayer myometrial repair of multiple large intramural myomas.

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  • [CommentIn] Fertil Steril. 2005 Aug;84(2):548-9; author reply 549-50 [16084915.001]
  • (PMID = 15652881.001).
  • [ISSN] 0015-0282
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] EFY6W0M8TG / Leuprolide
  • [Number-of-references] 164
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43. Glasser MH, Heinlein PK, Hung YY: Office endometrial ablation with local anesthesia using the HydroThermAblator system: Comparison of outcomes in patients with submucous myomas with those with normal cavities in 246 cases performed over 5(1/2) years. J Minim Invasive Gynecol; 2009 Nov-Dec;16(6):700-7
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  • [Title] Office endometrial ablation with local anesthesia using the HydroThermAblator system: Comparison of outcomes in patients with submucous myomas with those with normal cavities in 246 cases performed over 5(1/2) years.
  • STUDY OBJECTIVE: To estimate the safety and efficacy of the HydroThermAblator (HTA) system for performance of endometrial ablation in the medical office setting using local anesthesia and minimal oral sedation and to compare results obtained in patients with submucous myomas with those in patients with normal endometrial cavities.
  • DESIGN: Retrospective cohort analysis of 246 HTA procedures (Canadian Task Force classification II-2).
  • SETTING: Medical offices of a suburban community medical center that is part of a large health maintenance organization.
  • PATIENTS: Two hundred forty-six women aged 28 to 63 years (mean [SD], 45.1 [6.0] years) with abnormal uterine bleeding unresponsive to conservative management, including 104 patients (42.3%) with submucous myomas.
  • Type 0 or type I myomas were present in at least 86 patients with submucous myomas (82.7%) and ranged from 1 to 4 cm in greatest diameter.
  • In the other 18 patients, submucous myomas were not classified by type.
  • The anesthesia regimen was the same in patients with submucous myomas as in those with normal cavities, and the procedure was performed in exactly the same manner.
  • In the 95 patients with submucous myomas, amenorrhea was reported by 37 patients (38.9%), oligomenorrhea by 27 (28.4%), eumenorrhea by 9 (9.5%), and menorrhagia by 11 (11.6%).
  • All patients who underwent hysterectomy had multiple myomas, and 9 (81.8%) also had adenomyosis.
  • The failure rate in patients with submucous myomas and normal cavities was 23.2% and 3.7%, respectively (relative risk, 6.3; 95% confidence interval, 2.5-16.0).
  • While the failure rate in the group with myomas was statistically significantly higher than in the group without myomas, the failure rate in the myoma group was still comparable to that achieved using electrosurgical resection and ablation of similar types of myomas as reported in the literature.
  • The amenorrhea rate achieved in the myoma group (38.9%) was also comparable to that achieved in US Food and Drug Administration pivotal trials in patients with normal cavities treated using all of the nonhysteroscopic global ablation devices as well those treated using rollerball endometrial ablation.
  • The hysterectomy rate in patients with submucous myomas and normal cavities was 11.6% and 0.7%, respectively.
  • Although the success rate in patients with normal cavities was higher than that achieved in patients with submucous myomas, hysterectomy because of abnormal bleeding related to myomas was avoided in 88.4% of the group with myomas.

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  • (PMID = 19896596.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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44. McLucas B: Extra-gonadal collateral supply to uterine leiomyomata: a case report. Minim Invasive Ther Allied Technol; 2009;18(2):103-5
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  • Although the vast majority of uterine leiomyomata are supplied solely by the uterine arteries, myomata have been reported to recruit additional blood supply, especially from the ovarian arteries.

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  • (PMID = 19255926.001).
  • [ISSN] 1365-2931
  • [Journal-full-title] Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
  • [ISO-abbreviation] Minim Invasive Ther Allied Technol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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45. Imai A, Furui T, Hatano Y, Suzuki M, Suzuki N, Goshima S: Leiomyoma and rhabdomyoma of the vagina . Vaginal myoma. J Obstet Gynaecol; 2008 Aug;28(6):563-6
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  • [Title] Leiomyoma and rhabdomyoma of the vagina . Vaginal myoma.

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  • (PMID = 19003646.001).
  • [ISSN] 1364-6893
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 30
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46. Alessandri F, Lijoi D, Mistrangelo E, Ferrero S, Ragni N: Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas. J Minim Invasive Gynecol; 2006 Mar-Apr;13(2):92-7
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  • [Title] Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas.
  • DESIGN: Randomized study (Canadian Task Force classification I).

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  • (PMID = 16527709.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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47. Kotini A, Anastasiadis AN, Anninos P, Koutlaki N, Anastasiadis P: Nonlinear analysis of biomagnetic signals recorded from uterine myomas. Biomagn Res Technol; 2006;4:2
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  • [Title] Nonlinear analysis of biomagnetic signals recorded from uterine myomas.
  • OBJECTIVE: To determine if there is any non-linearity in the biomagnetic recordings of uterine myomas and to find any differences that may be present in the mechanisms underlying their signal dynamics.
  • Sixteen of them were characterised with large myomas and 8 with small ones.
  • RESULTS: Applying nonlinear analysis to the biomagnetic signals of the uterine myomas, we observed a clear saturation value for the group of large ones (mean = 11.35 +/- 1.49) and no saturation for the small ones.
  • CONCLUSION: The comparison of the saturation values in the biomagnetic recordings of large and small myomas may be a valuable tool in the evaluation of functional changes in their dynamic behavior.

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  • [ISSN] 1477-044X
  • [Journal-full-title] Biomagnetic research and technology
  • [ISO-abbreviation] Biomagn Res Technol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1484479
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48. Uimari O, Suomalainen-König S, Sakkinen N, Santala M, Nieminen P, Ryynanen M: Natural history of familial myomas. Eur J Obstet Gynecol Reprod Biol; 2006 Apr 1;125(2):255-8
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Natural history of familial myomas.
  • OBJECTIVE: To study the natural history of myomas in familial cases and to compare the tendencies of myomas between familial and non-familial cases.
  • STUDY DESIGN: Subjects with familial and non-familial myomas were identified from the hospital records and the reliable details of the myomas were collected.
  • RESULTS: In the familial cases there are several myomas, four or more.
  • In the non-familial cases, there is usually only one single myoma, which is bigger than in familial cases.
  • In familial cases, subjects have four or more myomas while in non-familial cases the fibroid is single and large.

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  • (PMID = 16188369.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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49. Maia H Jr, Casoy J, Pimentel K, Correia T, Athayde C, Cruz T, Coutinho EM: Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologies. Contraception; 2008 Dec;78(6):479-85
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  • [Title] Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologies.
  • BACKGROUND: The study was conducted to evaluate vascular endothelial growth factor (VEGF), Cox-2 and aromatase expression in the endometrium of uteri with myomas and other associated pathologies.
  • STUDY DESIGN: Hysteroscopy was performed in 118 women of reproductive age with myomas and menorrhagia, 40 of whom were using a pill containing 75 mcg gestodene+30 mcg ethinylestradiol.
  • RESULTS: In patients with myomas and menorrhagia, associated pathologies such as adenomyosis, endometrial polyps and endometriosis were found in 32%, 12% and 17% of cases, respectively.
  • CONCLUSION: Endogenous progesterone or combined oral contraceptives are potent inhibitors of VEGF, aromatase and Cox-2 expression in the endometrium of patients with myomas and menorrhagia.

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  • (PMID = 19014794.001).
  • [ISSN] 1879-0518
  • [Journal-full-title] Contraception
  • [ISO-abbreviation] Contraception
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral; 0 / Vascular Endothelial Growth Factor A; 4G7DS2Q64Y / Progesterone; EC 1.14.14.1 / Aromatase; EC 1.14.99.1 / Cyclooxygenase 2
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50. Alborzi S, Ghannadan E, Alborzi S, Alborzi M: A comparison of combined laparoscopic uterine artery ligation and myomectomy versus laparoscopic myomectomy in treatment of symptomatic myoma. Fertil Steril; 2009 Aug;92(2):742-7
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  • [Title] A comparison of combined laparoscopic uterine artery ligation and myomectomy versus laparoscopic myomectomy in treatment of symptomatic myoma.
  • PATIENT(S): Of 152 women with symptomatic uterine myomas necessitating surgical intervention who wished to retain their uteri, 65 underwent laparoscopic uterine artery ligation and myomectomy (experimental group) and 87 received laparoscopic myomectomy only (control group).
  • In the experimental group, the recurrence of myoma was 6.2%, and 98.1% of the patients reported symptoms improvement; however, in the control group, these figures were 20.75% and 83.1%, respectively (statistically significant).
  • CONCLUSION(S): This study demonstrated the superiority of laparoscopic uterine artery ligation combined with myomectomy in treatment of symptomatic myomas.

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  • (PMID = 18692826.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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51. Makris N, Vomvolaki E, Mantzaris G, Kalmantis K, Hatzipappas J, Antsaklis A: Role of a bipolar resectoscope in subfertile women with submucous myomas and menstrual disorders. J Obstet Gynaecol Res; 2007 Dec;33(6):849-54
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  • [Title] Role of a bipolar resectoscope in subfertile women with submucous myomas and menstrual disorders.
  • METHODS: From January 2000 to December 2005, we studied 59 women of reproductive age with menorrhagia, submucous myomas and one or more infertility factors.
  • Fifteen of the 59 women displayed submucous myoma type O (intracavitary), 34 displayed submucous myoma type I (less than 50% within the myometrium) and the remaining 10 women displayed myoma type II (over 50% being within the myometrium).
  • The mean age and standard deviation of these patients was 34.6 +/- 4.4 years and the average size of myomas was 15 +/- 10 mm.
  • Treatment of these myomas was by hysteroscopic resection using a bipolar resectoscope.
  • The pregnancy rate was notably higher when the sole reason of subfertility was the presence of myoma (54.16%), and when the size of the myoma was equal to 2.5 cm (75%) or more.
  • CONCLUSION: The use of the bipolar resectoscope in hysteroscopic removal of small submucous myomas is shown to be both feasible and effective in controlling menorrhagia and increasing the pregnancy rate in subfertile women, when submucous myomas are the only reason of infertility.

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  • (PMID = 18001453.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Japan
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52. Melli MS, Farzadi L, Madarek EO: Comparison of the effect of gonadotropin-releasing hormone analog (Diphereline) and Cabergoline (Dostinex) treatment on uterine myoma regression. Saudi Med J; 2007 Mar;28(3):445-50
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  • [Title] Comparison of the effect of gonadotropin-releasing hormone analog (Diphereline) and Cabergoline (Dostinex) treatment on uterine myoma regression.
  • OBJECTIVE: To investigate the effect of cabergoline (Dostinex, a dopamine agonist) on the myoma growth compared to Diphereline (a gonadotropin-releasing hormone agonist).
  • Fifty women with uterine myoma, who met the criteria of the study thoroughly, were randomly allocated into 2 equal groups to take either Diphereline or Cabergoline.
  • The tumor regressed significantly and volume reduction rate of individual tumor nodule varied from 46-53%.
  • The gonadotropin releasing hormone agonist group all responded to the treatment, and volume reduction rate of the individual tumor nodule varied from 21-97%.
  • The extent of tumor shrinkage was positively correlated to the number of nodules (p=0.881, p<0.005 and 0.701, p<0.005).
  • [MeSH-minor] Adult. Biopsy, Needle. Dose-Response Relationship, Drug. Drug Administration Schedule. Female. Follow-Up Studies. Humans. Infusions, Intravenous. Middle Aged. Neoplasm Staging. Prospective Studies. Risk Assessment. Treatment Outcome

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  • (PMID = 17334477.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Ergolines; 33515-09-2 / Gonadotropin-Releasing Hormone; LL60K9J05T / cabergoline
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53. Bodle JF, Duffy SR, Binney DM: Susceptibility of uterine myomas and endometrium to cryosurgery using a carbon dioxide cryosurgical probe in vitro. J Minim Invasive Gynecol; 2006 Nov-Dec;13(6):500-4
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  • [Title] Susceptibility of uterine myomas and endometrium to cryosurgery using a carbon dioxide cryosurgical probe in vitro.
  • STUDY OBJECTIVE: To determine the effect of a 9-mm diameter carbon dioxide cryoprobe, the Endocryo, on myomas and endometrial/myometrial tissue in vitro.
  • DESIGN: Comparative laboratory study (Canadian Task Force classification II-2).
  • PATIENTS: Women with and without myomas, undergoing hysterectomy.
  • INTERVENTION: A single 5-minute freeze followed by an active thaw was applied to uterine myomas and endometrial/myometrial tissue in vitro.
  • MEASUREMENTS AND MAIN RESULTS: Endometrial/myometrial and uterine myoma temperature change was measured continuously during the cryosurgical procedure.
  • There was no significant difference in temperature change and depth of cell death between myomas and endometrial/myometrial tissue in vitro.
  • CONCLUSIONS: The Endocryo produces the same cryosurgical effect on both uterine myomas and endometrial/myometrial tissue in vitro, an important principal for future development of a clinically effective cryosurgical device for the treatment of menorrhagia in the presence of submucous myomas.

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  • (PMID = 17097569.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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54. Marshburn PB, Matthews ML, Hurst BS: Uterine artery embolization as a treatment option for uterine myomas. Obstet Gynecol Clin North Am; 2006 Mar;33(1):125-44
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  • [Title] Uterine artery embolization as a treatment option for uterine myomas.
  • A prospective study of "contemporaneous cohorts," which excluded patients who had sub-mucosal and pedunculated subserosal myomas, sought to compare quality of life measures and adverse events in patients who underwent UAE or hysterectomy.
  • Furthermore, hysterectomy eliminates uterine bleeding and the risk for recurrence of myomas.
  • After McLucas advocated that gynecologists learn the skill to perform UAE for managing symptomatic myomas, the Society of Interventional Radiology responded with a precautionary commentary on the level of technical proficiency that is necessary to maintain optimum results from UAE.
  • The gynecologist is likely to be the primary initial consultant to patients who present with complaints of symptomatic myomas.
  • Because some women may experience ovarian failure after UAE, additional studies to determine basal follicle-stimulating hormone and estradiol before and after the procedure may provide insight into UAE-induced follicle depletion.UAE is a unique new treatment for uterine myomas, and is no longer considered investigational for symptomatic uterine fibroids.
  • There is international recognition that data are needed from RCTs that compare UAE with surgical alternatives.
  • FIBROID should provide critical data for the assessment of safety and outcomes measures for women who receive UAE for symptomatic uterine myomas.

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  • (PMID = 16504811.001).
  • [ISSN] 0889-8545
  • [Journal-full-title] Obstetrics and gynecology clinics of North America
  • [ISO-abbreviation] Obstet. Gynecol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 92
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55. Buyukkurt S, Yuksel A, Seydaoglu G, Has R, Kadayifci O: The effect of amniocentesis on preterm delivery rate in women with uterine myoma. Clin Exp Obstet Gynecol; 2010;37(1):33-6
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  • [Title] The effect of amniocentesis on preterm delivery rate in women with uterine myoma.
  • OBJECTIVES: To evaluate the effect of genetic amniocentesis on the preterm delivery rate in women with uterine myoma.
  • RESULTS: During the study 14,579 pregnant women were examined and 234 had complications of uterine myomas (1.61%).
  • The results revealed that multifocal fibroids in relation to the myometrium, uterine myoma subjacent to the placenta, total myoma volume greater than 150 cm3 are statistically significant independent risk factors for preterm delivery, while amniocentesis was not found to be an independent risk factor for preterm delivery.
  • CONCLUSIONS: Although having uterine myoma is a fairly known cause of preterm delivery, second trimester genetic amniocentesis does not seem to have any additional adverse effect on the preterm delivery rate in women with uterine myomas.
  • [MeSH-major] Amniocentesis. Myoma / epidemiology. Premature Birth / epidemiology. Uterine Neoplasms / epidemiology

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  • (PMID = 20420278.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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56. Dane B, Dane C, Basaran S, Erginbas M, Cetin A: Vaginal Schwannoma in a case with uterine myoma. Ann Diagn Pathol; 2010 Apr;14(2):137-9
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  • [Title] Vaginal Schwannoma in a case with uterine myoma.
  • We report a case of vaginal schwannoma associated with uterine myoma.
  • A 52-year-old woman presented with lower abdominal pain and menorrhagia for a duration of 6 months.
  • At sonographic examination, the patient was found to have uterine myomas and a solid mass measuring 5x4.5 cm beneath the vaginal wall.
  • At laparotomy, the uterus with myoma was removed using our standard operation procedures.
  • The tumor cells were vimentin (+), desmin (-), smooth muscle alpha-actin (-), HMB-45 (-), MART-1 (-) and S-100 (+).
  • The differential diagnosis of a mass in the vagina includes also schwannomas.
  • Immunocytochemical labeling of the tumor cells is essential.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20227020.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Ciavattini A, Tsiroglou D, Tranquilli AL, Litta P: Laparoscopic versus ultraminilaparotomic myomectomy for the treatment of large uterine myomas. Acta Obstet Gynecol Scand; 2010;89(1):151-5
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  • [Title] Laparoscopic versus ultraminilaparotomic myomectomy for the treatment of large uterine myomas.
  • We compared short-term surgical outcomes of laparoscopic and ultraminilaparotomic procedures for the treatment of large uterine myomas in a retrospective matched-control study (Canadian Task Force classification II-2) of 32 women with large myomas who underwent laparoscopic myomectomy and 32 women who had ultraminilaparotomic myomectomy (< or =4 cm incision).
  • Laparoscopic myomectomy seems to be the preferable approach for the treatment of large myomas of > or =5 cm, providing a more rapid recovery compared to the ultraminilaparotomic approach.

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  • (PMID = 19878068.001).
  • [ISSN] 1600-0412
  • [Journal-full-title] Acta obstetricia et gynecologica Scandinavica
  • [ISO-abbreviation] Acta Obstet Gynecol Scand
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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58. Kanaoka Y, Yoshida C, Tsukioka M, Noriyuki M, Ishiko O: Ratio of directly necrotized volume to total volume of a submucosal myoma predicts shrinkage after microwave endometrial ablation. J Obstet Gynaecol Res; 2009 Aug;35(4):717-24
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  • [Title] Ratio of directly necrotized volume to total volume of a submucosal myoma predicts shrinkage after microwave endometrial ablation.
  • AIM: To explore parameters relating to shrinkage of submucosal myomas after microwave endometrial ablation.
  • METHODS: Fourteen patients underwent microwave endometrial ablation at 2.45 GHz using a curved microwave applicator to treat menorrhagia caused by a submucosal myoma.
  • The size of myomas was measured on magnetic resonance images before, one month after, and six months after the operation.
  • The average radius r was defined as half of the size of the myoma measured in three dimensions.
  • The protrusion ratio alpha was defined as the ratio of the thickness of the protruding part of a myoma in the uterine cavity to the size of the myoma before the operation.
  • The ratio of the directly necrotized volume by microwave irradiation to the total volume (RODNeV) of preoperative myomas was calculated using the following formula:.
  • (1) where d is the depth of myoma tissue directly necrotized by microwave irradiation.
  • RESULTS: Two-dimensional plots showing shrinkage of submucosal myomas versus the RODNeV indicated that shrinkage at six months after microwave endometrial ablation depends on the RODNeV.
  • Myomas with a RODNeV greater than 0.17 had shrunk more than 50% at six months after the operation.
  • CONCLUSIONS: RODNeV is closely related to postoperative necrosis and shrinkage of the submucosal myoma after microwave endometrial ablation.
  • Prediction of the shrinkage rate of submucous myomas appears to be possible by calculating the RODNeV preoperatively.

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  • (PMID = 19751333.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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59. Cramer SF, Mann L, Calianese E, Daley J, Williamson K: Association of seedling myomas with myometrial hyperplasia. Hum Pathol; 2009 Feb;40(2):218-25
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  • [Title] Association of seedling myomas with myometrial hyperplasia.
  • Myometrial hyperplasia (MMH) is a common structural variation characterized by irregular zones of increased myometrial cellularity, with increased nucleus-cell ratios; but to date, there has been only anecdotal evidence that it may give rise to myomas.
  • We studied the relationship of seedling myomas to MMH in 50 consecutive hysterectomies and found that most seedling myomas (44/63, 70%) arose in MMH--35 in inframucosal MMH, 3 in subserosal MMH, and 6 from intramural MMH.
  • Some seedling myomas were incompletely circumscribed, seeming to arise not only in but also from MMH.
  • We suggest that even seedlings in normal myometrium may arise not from normal myometrial smooth muscle cells but rather from myometaplasia in intramural stromal emboli, with hyperplastic and then neoplastic transformation.

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  • (PMID = 18799191.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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60. Funaki K, Fukunishi H, Funaki T, Kawakami C: Mid-term outcome of magnetic resonance-guided focused ultrasound surgery for uterine myomas: from six to twelve months after volume reduction. J Minim Invasive Gynecol; 2007 Sep-Oct;14(5):616-21
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  • [Title] Mid-term outcome of magnetic resonance-guided focused ultrasound surgery for uterine myomas: from six to twelve months after volume reduction.
  • STUDY OBJECTIVE: To clarify the volume change ratio of uterine myomas treated with magnetic resonance-guided focused ultrasound surgery (MRgFUS), in relation to the signal intensity of T(2)-weighted magnetic resonance (MR) images.
  • DESIGN: Prospective study (Canadian Task Force classification II-3).
  • PATIENTS: Forty-eight myomas in 35 patients were followed up with MR images 6 months after MRgFUS, and 23 myomas in 17 patients were followed up 12 months after MRgFUS.
  • Before treatment, the myomas were classified into 3 types on the basis of the signal intensity of T(2)-weighted MR images as follows: Type 1, low intensity; type 2, intermediate intensity; type 3, high intensity.
  • MEASUREMENTS AND MAIN RESULTS: MRgFUS produced a greater volume reduction in type 1 and type 2 myomas than in type 3 myomas.
  • Nonperfused areas always diminished in the period after MRgFUS; however, the volume change was affected by the volume change ratio of perfused areas inside the treated myomas.
  • CONCLUSION: At present, type 3 myomas should be exempted from the application of MRgFUS, because the nonperfused ratio immediately after the procedure was small compared with that in type 1 and type 2 myomas, and the subsequent volume change was unfavorable.

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  • (PMID = 17848324.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Jindabanjerd K, Taneepanichskul S: The use of levonorgestrel - IUD in the treatment of uterine myoma in Thai women. J Med Assoc Thai; 2006 Oct;89 Suppl 4:S147-51
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  • [Title] The use of levonorgestrel - IUD in the treatment of uterine myoma in Thai women.
  • OBJECTIVE: This study was designed to evaluate the potential usefulness of the levonorgestrel-releasing intrauterine device (LNG - IUD ; Mirena) in treating women with uterine myomas.
  • SUBJECTS: Sixteen women with uterine myomas who intended to receive treatment with the LNG IUD.
  • MAIN OUTCOME MEASURES: Myoma and Uterine volume, menstrual blood loss assessed with pictorial blood loss assessment charts and hematocrit.
  • RESULTS: Use of the LNG IUD was associated with a statistically significant reduction in the total myoma volume, average uterine size and marked reduction in menstrual blood loss.
  • After 6 months of use, the median total myoma volume decreased from 19.82 mL to 11.63 mL (p < 0.05), median pictorial blood loss assessment chart score declined from 89 to 3 (p < 0.05).
  • CONCLUSION: The LNG IUD was associated with a profound reduction in myoma and uterine volume.
  • For women with myomas of this size, the LNG IUD provides effective medical treatment of bleeding.
  • [MeSH-major] Contraceptives, Oral, Synthetic / therapeutic use. Intrauterine Devices, Medicated. Levonorgestrel / therapeutic use. Myoma / drug therapy. Uterine Neoplasms / drug therapy

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  • (PMID = 17726816.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Contraceptives, Oral, Synthetic; 5W7SIA7YZW / Levonorgestrel
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62. Liu WM, Wang PH, Chou CS, Tang WL, Wang IT, Tzeng CR: Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas. Fertil Steril; 2007 Feb;87(2):356-61
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  • [Title] Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas.
  • OBJECTIVE: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone.
  • PATIENT(S): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus.
  • MAIN OUTCOME MEASURE(S): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups.
  • The recurrence rate of uterine myomas was 5.8% (3 of 52) in group I and 36.7% (11 of 30) in group II during an average follow-up period of 42.5 months.
  • CONCLUSION(S): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.
  • [MeSH-major] Laparoscopy / methods. Laparotomy / methods. Leiomyoma / surgery. Neoplasm Recurrence, Local / surgery. Uterine Neoplasms / surgery. Uterus / blood supply. Uterus / surgery

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  • [CommentIn] Fertil Steril. 2007 Sep;88(3):758-9; author reply 759 [17681320.001]
  • (PMID = 17069812.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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63. Bettocchi S, Di Spiezio Sardo A, Ceci O, Nappi L, Guida M, Greco E, Pinto L, Camporiale AL, Nappi C: A new hysteroscopic technique for the preparation of partially intramural myomas in office setting (OPPIuM technique): A pilot study. J Minim Invasive Gynecol; 2009 Nov-Dec;16(6):748-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A new hysteroscopic technique for the preparation of partially intramural myomas in office setting (OPPIuM technique): A pilot study.
  • OBJECTIVE: To assess the safety and the effectiveness of a novel hysteroscopic technique for the Office Preparation of Partially Intramural Myomas (OPPIuM), to facilitate the subsequent, already scheduled, resectoscopic myomectomy.
  • PATIENTS: Fifty-nine fertile women (age 27-48 years) diagnosed at office hysteroscopy as having symptomatic submucous myomas>1.5 cm with intramural development (G1 and G2), scheduled for resectoscopic surgery.
  • INTERVENTIONS: The OPPIuM technique consisted of an incision of the endometrial mucosa covering the myoma by means of Fr scissors or bipolar Versapoint Twizzle electrode, along its reflection line on the uterine wall, up to the precise identification of the cleavage surface between the myoma and its pseudo-capsule.
  • Such procedure was aimed at triggering the protrusion of the intramural portion of the myoma into the uterine cavity during the following menstrual cycles, thus facilitating the subsequent total removal of the lesion via resectoscopic surgery.
  • The mean diameter of successfully prepared myomas was 2.9+/-0.8 cm.
  • At follow-up hysteroscopy, the conversion of partially intramural myomas into totally or prevalently intracavitary ones was observed in 93.2% (55/59) of cases.
  • In 2 of 3 cases of failure, the myomas' size was>4 cm.
  • One patient was excluded from the study because of the occurrence of total spontaneous expulsion of the myoma at the subsequent menstrual cycle.
  • CONCLUSIONS: Our preliminary findings seem to support the safety and the effectiveness of the OPPIuM procedure by reporting the conversion of myomas with intramural development>1.5 cm into totally or prevalently intracavitary ones in nearly 93% of cases.
  • [MeSH-major] Ambulatory Surgical Procedures. Hysteroscopy / methods. Myoma / surgery. Uterine Neoplasms / surgery

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  • (PMID = 19896603.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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64. Bettocchi S, Siristatidis C, Pontrelli G, Di Spiezio Sardo A, Ceci O, Nappi L, Selvaggi L: The destiny of myomas: should we treat small submucous myomas in women of reproductive age? Fertil Steril; 2008 Oct;90(4):905-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The destiny of myomas: should we treat small submucous myomas in women of reproductive age?
  • OBJECTIVE: To carry out a thorough analysis aimed at demonstrating that a "wait-and-see" approach is no longer acceptable in women of reproductive age with small submucous myomas, even if they are asymptomatic.
  • PATIENT(S): Women of reproductive age with small (<1.5 cm) submucous myomas.
  • MAIN OUTCOME MEASURES(S): a) The real endometrial surface and volume occupied by a submucous myoma;.
  • b) the high potential of a small myoma to grow during the reproductive age;.
  • d) the inability to perform a reliable and "safe" diagnosis, with respect to malignancy, without an eye-guided biopsy; and e) the effectiveness of "see-and-treat" hysteroscopy in removing small submucous myomas.
  • RESULT(S): Small myomas, as hormone-dependent benign tumors, have a high potential to grow and either to become symptomatic or to cause complications during natural or assisted conception and pregnancy.
  • "See-and-treat" hysteroscopy has been demonstrated to be safe and effective in removing such small submucous myomas.
  • CONCLUSION(S): A "wait-and-see" approach is no longer acceptable in women of reproductive age with small submucous myomas, especially if the lesion could be easily and safely removed in an outpatient setting with minimal patient's discomfort.
  • [MeSH-major] Infertility, Female / epidemiology. Infertility, Female / prevention & control. Leiomyoma / surgery. Myoma / epidemiology. Myoma / surgery. Risk Assessment / methods. Uterine Neoplasms / epidemiology. Uterine Neoplasms / surgery

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  • (PMID = 18163996.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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65. Scott RS, Blank KL, Proffer LH, Kraus EW, Heim-Hall J: Perivascular myoma of myopericytoma and myofibromatosis-type arising in a chronic scar. J Cutan Pathol; 2006 Mar;33(3):231-5
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  • [Title] Perivascular myoma of myopericytoma and myofibromatosis-type arising in a chronic scar.
  • We describe a case of a cutaneous perivascular myoma with features overlapping between the myofibromatosis and the myopericytoma type.
  • Immunohistochemical stains showed focal positivity for smooth muscle actin.
  • Immunohistochemical and ultrastructural studies have showed these pericyte-like cells to be of a myoid origin.
  • We report the first case of a cutaneous perivascular myoma arising in a chronic scar.
  • [MeSH-major] Cicatrix / pathology. Hemangiopericytoma / pathology. Myofibromatosis / pathology. Myoma / pathology. Neoplasms, Vascular Tissue / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Chronic Disease. Female. Humans. Immunoenzyme Techniques. Middle Aged. Pericytes / pathology. Treatment Outcome

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  • (PMID = 16466511.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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66. Wang PH, Liu WM, Fuh JL, Chao HT, Yuan CC, Chao KC: Symptomatic myoma treated with laparoscopic uterine vessel occlusion and subsequent immediate myomectomy: which is the optimal surgical approach? Fertil Steril; 2009 Aug;92(2):762-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic myoma treated with laparoscopic uterine vessel occlusion and subsequent immediate myomectomy: which is the optimal surgical approach?
  • PATIENT(S): One hundred thirty-one patients with symptomatic myomas underwent LUVO plus laparoscopic myomectomy (LM; LUVO+LM) (n = 49) or LUVO plus ultra-mini laparotomy UMLT-M (LUVO+UMLT-M) (n = 82).
  • RESULT(S): General characteristics of the patients were similar in both groups, except the number of myomas.
  • [MeSH-major] Hemostasis, Surgical / methods. Laparoscopy / methods. Leiomyoma / surgery. Myoma / surgery. Uterine Neoplasms / surgery. Uterus / blood supply. Uterus / surgery

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  • (PMID = 18930209.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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67. Bonito M, Gulemì L, Basili R, Brunetti G, Roselli D: Thrombosis associated with a large uterine myoma: case report. Clin Exp Obstet Gynecol; 2007;34(3):188-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thrombosis associated with a large uterine myoma: case report.
  • A case of a 49-year-old woman who presented with a large uterine myoma weighing 5000 g and was affected by unilateral deep vein thrombosis of the left leg and pulmonary embolism is presented.


68. Tintara H, Aiyarak P, Mitarnun W, Geater A: Effect of thread pitch on pull-out strength of laparoscopic myoma screws. J Obstet Gynaecol Res; 2006 Aug;32(4):428-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of thread pitch on pull-out strength of laparoscopic myoma screws.
  • AIM: The purpose of this study was to evaluate the effect of thread-pitch on pull-out strength and bending strength of buttress-thread screws designed for laparoscopic myoma extraction.
  • METHODS: The ultimate failure load of four 5-mm diameter buttress-thread screws with 3-, 4-, 5-, and 6-mm thread pitch, 40 mm in thread-length were examined on fresh myoma specimens.
  • The myoma tissue at each traction site was evaluated histologically to determine its density.
  • The critical minimal pull-out strength based on moderate-density myoma group was estimated.
  • In moderate-density myomas, the mean ultimate failure loads decreased linearly with increasing thread-pitch from 3 mm (148.0 +/- 9.5 N) to 6 mm (119.8 +/- 9.4 N) (test for trend: P < 0.05).
  • Based on the criterion of a minimum pull-out strength of at least 50 N in not less than 95% of tractions in medium-density myomas, the 3-mm and 5-mm pitch screws were found to have acceptable properties.
  • Thread-pitch should be considered when designing laparoscopic myoma-screws.
  • [MeSH-major] Laparoscopy / methods. Myoma / surgery

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  • (PMID = 16882270.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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69. Muller Vranjes A, Popović Z, Vlahović I, Habek D, Kasac Z: Heterotopic trigeminal pregnancy in infertile women after ovulation stimulation and embolisation of a uterine myoma. Fetal Diagn Ther; 2006;21(1):81-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Heterotopic trigeminal pregnancy in infertile women after ovulation stimulation and embolisation of a uterine myoma.
  • In this report, we describe the case of a 34-year-old nulliparous woman who became pregnant after ovulation induction with clomiphene.
  • According to her gynaecologic history, she had embolisation of a uterine myoma.

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  • [Copyright] (c) 2006 S. Karger AG, Basel
  • (PMID = 16354982.001).
  • [ISSN] 1015-3837
  • [Journal-full-title] Fetal diagnosis and therapy
  • [ISO-abbreviation] Fetal. Diagn. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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70. Kanaoka Y, Hirai K, Ishiko O: Microwave endometrial ablation for menorrhagia caused by large submucous myomas. J Obstet Gynaecol Res; 2005 Dec;31(6):565-70
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  • [Title] Microwave endometrial ablation for menorrhagia caused by large submucous myomas.
  • AIM: To examine the feasibility of microwave endometrial ablation (MEA), using a curved microwave applicator, in patients with menorrhagia caused by a submucous myoma greater than 3 cm in diameter, which is among the contraindications for conventional endometrial ablation.
  • METHODS: Patients included were refractory to medication, more than 45 years of age, and due to undergo hysterectomy to treat menorrhagia as a result of submucous myomas, although they hoped to avoid hysterectomy.
  • Patients 1, 2 and 3 had submucous myoma nodes 4.5, 5.0 and 13 cm in diameter respectively.
  • Microwaves were irradiated at 40 W for 50 s for single irradiation sites.
  • CONCLUSION: Microwave endometrial ablation improves menorrhagia caused by large submucous myomas when the microwave applicator reaches all parts of the uterine cavity.

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  • (PMID = 16343261.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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71. Sinha R, Sundaram M, Lakhotia S, Mahajan C, Manaktala G, Shah P: Total laparoscopic hysterectomy for large uterus. J Gynecol Endosc Surg; 2009 Jan;1(1):34-9

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  • We have analyzed whether it is possible for an experienced laparoscopic surgeon to perform efficient total laparoscopic hysterectomy for large myomatous uteri regardless of the size, number and location of the myomas.
  • DESIGN: Retrospective review (Canadian Task Force Classification II-1) SETTING: Dedicated high volume Gynecological laparoscopy centre.
  • PATIENTS: 173 women with symptomatic myomas who underwent total laparoscopic hysterectomy at our center.
  • There were no exclusion criteria based on the size number or location of myomas.
  • It can be performed by experienced surgeons for large uteri regardless of the size, number or location of the myomas.

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  • (PMID = 22442509.001).
  • [ISSN] 0974-1216
  • [Journal-full-title] Journal of gynecological endoscopy and surgery
  • [ISO-abbreviation] J Gynecol Endosc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3304266
  • [Keywords] NOTNLM ; Large uterus / multiple fibroids / total laparoscopic hysterectomy
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72. Tinelli A, Malvasi A, Hudelist G, Cavallotti C, Tsin DA, Schollmeyer T, Bojahr B, Mettler L: Laparoscopic intracapsular myomectomy: comparison of single versus multiple fibroids removal. An institutional experience. J Laparoendosc Adv Surg Tech A; 2010 Oct;20(8):705-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Group I included 195 patients with myoma; group II, 140 patients with multiple myomas, 4-9 cm in diameter.

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  • (PMID = 20701546.001).
  • [ISSN] 1557-9034
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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73. Shipovskiĭ VN: [Annual Congress of the Cardiovascular and Interventional Radiological Society of Europe (CIRSE-2009) September 18-21, 2009, Lisbon, Portugal]. Angiol Sosud Khir; 2010;16(1):57-64

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  • The Forum centred upon recent achievements in such currently important trends of interventional radiology as carotid stenting, transcatheterembolization, endovascular prosthetic reconstruction of the aorta and its branches, angioplasty of the crural arteries in diabetic foot, prevention of pulmonary artery thromboembolism, peripheral interventions on lower-limb arteries, as well as interventions on the hepatic bile ducts in mechanical jaundice, transjugular intrahepaticportosystemic shunt (TIPS) procedures, embolization ofuterine arteries in womb myoma, vertebroplasty, venous interventions, interventions in renal artery stenoses, etc.

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  • (PMID = 20635717.001).
  • [ISSN] 1027-6661
  • [Journal-full-title] Angiologii︠a︡ i sosudistai︠a︡ khirurgii︠a︡ = Angiology and vascular surgery
  • [ISO-abbreviation] Angiol Sosud Khir
  • [Language] rus
  • [Publication-type] Congresses; English Abstract
  • [Publication-country] Russia (Federation)
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74. Grimbizis GF, Tsolakidis D, Mikos T, Anagnostou E, Asimakopoulos E, Stamatopoulos P, Tarlatzis BC: A prospective comparison of transvaginal ultrasound, saline infusion sonohysterography, and diagnostic hysteroscopy in the evaluation of endometrial pathology. Fertil Steril; 2010 Dec;94(7):2720-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SETTING: Obstetrics and Gynecology Department of a tertiary academic hospital.
  • However, SIS was more accurate compared to Tvs. CONCLUSION(S): Saline infusion sonohysterography appears to be more valuable than TVS in the diagnosis of intracavitary masses (both polyps and myomas).
  • [MeSH-major] Hysteroscopy / methods. Sodium Chloride / administration & dosage. Uterine Diseases / radiography. Uterine Diseases / ultrasonography. Uterus / ultrasonography. Vagina / ultrasonography

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20462577.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Comparative Study; Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
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75. Del Priore G, Klapper AS, Gurshumov E, Vargas MM, Ungar L, Smith JR: Rescue radical trachelectomy for preservation of fertility in benign disease. Fertil Steril; 2010 Oct;94(5):1910.e5-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rescue radical trachelectomy for preservation of fertility in benign disease.
  • OBJECTIVES: To report a series of patients treated with modified radical abdominal trachelectomy to preserve fertility in benign disease that would normally result in hysterectomy.
  • PATIENT(S): Of the >160 radical abdominal trachelectomies we performed, four cases were performed for benign indications.
  • Two myomectomy patients had intraoperative consultation and a third had preoperative consultation for large lower segment/cervical myomas with conversion to trachelectomy rather than hysterectomy.
  • CONCLUSION(S): Although traditionally performed with cervical cancer, radical abdominal trachelectomy can be modified to preserve fertility for benign indications that would otherwise require hysterectomy.
  • [MeSH-major] Endometriosis / surgery. Fertility. Gynecologic Surgical Procedures / methods. Leiomyoma / surgery. Myoma / surgery. Uterine Diseases / surgery. Uterine Neoplasms / surgery

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20416873.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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76. Zullo F, Falbo A, Iuliano A, Oppedisano R, Sacchinelli A, Annunziata G, Venturella R, Materazzo C, Tolino A, Palomba S: Randomized controlled study comparing the Gynecare Morcellex and Rotocut G1 tissue morcellators. J Minim Invasive Gynecol; 2010 Mar-Apr;17(2):192-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS: Seventy-four patients with symptomatic uterine myomas scheduled for laparoscopic supracervical hysterectomy or myomectomy.
  • [MeSH-minor] Adult. Cost-Benefit Analysis. Equipment Design. Female. Humans. Middle Aged. Treatment Outcome. Tumor Burden

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  • [Copyright] Copyright 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20226407.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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77. Sahin K, Akdemir F, Tuzcu M, Sahin N, Onderci M, Ozercan R, Ilhan N, Kilic E, Seren S, Kucuk O: Genistein suppresses spontaneous oviduct tumorigenesis in quail. Nutr Cancer; 2009;61(6):799-806
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This makes it a good animal model for screening potential agents for testing in the prevention and treatment of human myoma uteri.
  • [MeSH-minor] Animals. Avian Proteins / metabolism. Biomarkers / blood. Connexin 43 / metabolism. Coturnix. Dose-Response Relationship, Drug. Female. Humans. Incidence. Isoflavones / blood. Oxidative Stress / drug effects. Proto-Oncogene Proteins c-bcl-2 / metabolism. Random Allocation. Tumor Burden. Uterine Neoplasms / prevention & control. bcl-2-Associated X Protein / metabolism

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  • (PMID = 20155619.001).
  • [ISSN] 1532-7914
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 0 / Avian Proteins; 0 / Biomarkers; 0 / Connexin 43; 0 / Isoflavones; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-2-Associated X Protein; DH2M523P0H / Genistein
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78. Sinha R, Lakhotia S, Sundaram M, Manaktala G, Shah P, Mahajan C: Retained uterine fundus after vaginal hysterectomy. J Minim Invasive Gynecol; 2010 Jan-Feb;17(1):94-6
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  • Retained uterine tissue or myoma tissue has been reported, usually after morcellation.

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  • [Copyright] Copyright (c) 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20129338.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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79. Markowska A, Ziolkowska A, Nowinka K, Malendowicz LK: Elevated blood active ghrelin and normal total ghrelin and obestatin concentrations in uterine leiomyoma. Eur J Gynaecol Oncol; 2009;30(3):281-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the control group the ratio of active to total ghrelin concentrations amounted to 0.62, while in women with uterine myoma it was 0.95, pointing to a prevalence of the active form of ghrelin in women with uterine myoma.
  • The data may suggest a role of active ghrelin in the development of a myoma.

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  • (PMID = 19697621.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Ghrelin
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80. Raga F, Sanz-Cortes M, Bonilla F, Casañ EM, Bonilla-Musoles F: Reducing blood loss at myomectomy with use of a gelatin-thrombin matrix hemostatic sealant. Fertil Steril; 2009 Jul;92(1):356-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reducing blood loss at myomectomy with use of a gelatin-thrombin matrix hemostatic sealant.
  • MAIN OUTCOME MEASURE(S): Patient age, parity, number of myomas, operative time, blood loss, transfusion, intraoperative and postoperative complications, and length of hospitalization were evaluated.
  • [MeSH-major] Blood Loss, Surgical / prevention & control. Hemostatics / therapeutic use. Leiomyoma / surgery. Myoma / surgery. Uterine Neoplasms / surgery

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  • (PMID = 19423098.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemostatics; 9000-70-8 / Gelatin; EC 3.4.21.5 / Thrombin
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81. Domingues AP, Lopes H, Dias I, De Oliveira CF: Endometrial polyps in postmenopausal women. Acta Obstet Gynecol Scand; 2009;88(5):618-20
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  • Transvaginal ultrasound revealed abnormal endometrial thickness in 60.0% vs. 57.7%, polyps in 37.9% vs. 32.9%, endometrial tumors in 1.3% vs. 0.8%, and submucosal myomas in 0.9% vs. 2.0% by the absence or presence of bleeding.

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  • (PMID = 19267270.001).
  • [ISSN] 1600-0412
  • [Journal-full-title] Acta obstetricia et gynecologica Scandinavica
  • [ISO-abbreviation] Acta Obstet Gynecol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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82. O'Hanlan KA: Cystosufflation to prevent bladder injury. J Minim Invasive Gynecol; 2009 Mar-Apr;16(2):195-7
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  • Indications included finding of adhesions from earlier cesarean section or massive myomas obscuring bladder margins, or planned anterior colpopexy or vaginal sacrocolpopexy.

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  • (PMID = 19138575.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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83. Chang WC, Huang SC, Sheu BC, Shih JC, Hsu WC, Chen SY, Chang DY: Changes in uterine blood flow following laparoscopic myomectomy with or without uterine artery ligation on two- and three-dimensional power Doppler ultrasound. Ultrasound Obstet Gynecol; 2009 Feb;33(2):221-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: From November 2005 to July 2007, we enrolled prospectively 105 women with symptomatic myomas who were scheduled to undergo laparoscopic myomectomy (57 with UAL (study group) and 48 without (control group)).
  • RESULTS: Characteristics of the myomas, operative time and duration of hospital stay were comparable between the two groups, whereas the median (range) of estimated blood loss (50 (50-200) vs. 100 (50-900) mL, P = 0.001) and the frequency of excessive bleeding of > 500 mL (0% vs. 10%, P = 0.018) were significantly lower in the study group.
  • CONCLUSION: Concurrent UAL during laparoscopic myom- ectomy reduces the intraoperative blood loss and frequency of excessive bleeding without permanently compromising uterine perfusion.
  • [MeSH-major] Myoma / blood supply. Uterine Neoplasms / blood supply. Uterus / blood supply

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  • (PMID = 19086039.001).
  • [ISSN] 1469-0705
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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84. Zhang YX: Artificial neural networks based on principal component analysis input selection for clinical pattern recognition analysis. Talanta; 2007 Aug 15;73(1):68-75

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  • One data set contains 168 clinical urinary samples, of which 84 specimens are from female thyroid cancer patients (malignant tumour group), and the other samples were collected from healthy women (normal group).
  • In all the specimens, each number of the samples for both uterine cervical cancer patients (malignant tumour group) and healthy females (normal group) is 60, and the other 48 samples were collected from uterine myoma patients (benign tumour group).

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  • (PMID = 19071851.001).
  • [ISSN] 1873-3573
  • [Journal-full-title] Talanta
  • [ISO-abbreviation] Talanta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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85. Visnovský J, Galo S, Zúbor P, Hatok J, Racay P, Danko J: [Semiquantitative analysis of mRNA aromatase expression in eutopic endometrium as a diagnostic marker of endometriosis and estrogen dependent diseases]. Ceska Gynekol; 2008 Jul;73(4):213-7
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Semiquantitative analysis of mRNA aromatase expression in eutopic endometrium as a diagnostic marker of endometriosis and estrogen dependent diseases].
  • METHODS: The expression of mRNA aromatase of eutopic endometrium was determined among women who underwent laparoscopy or laparotomy due to pelvic pain, infertility or benign pelvic tumor.
  • By the presence of estrogen-dependent diseases- endometriosis, myomas or endometrial hyperplasia 18 women were compared to 5 disease free women.

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  • (PMID = 18711959.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] SLO
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Estrogens; 0 / RNA, Messenger; EC 1.14.14.1 / Aromatase
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86. Renner SP, Strick R, Fasching PA, Oeser S, Oppelt P, Mueller A, Beckmann MW, Strissel PL: Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk. Am J Obstet Gynecol; 2008 Dec;199(6):648.e1-9
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk.
  • OBJECTIVE: Uterine benign leiomyomas result from proliferation of a single smooth-muscle cell and their growth is affected by steroid hormones via steroid hormone receptors.
  • This investigation analyzed the +331G/A and the V600L single nucleotide polymorphisms in the progesterone receptor, and correlated their incidence with clinical and tumor parameters as well as disease risk.
  • RESULTS: No correlation was found for both single nucleotide polymorphisms or the risk for developing myoma; however, statistical significant associations were found for single nucleotide polymorphism genotypes with specific clinical and tumor characteristics, eg, endometriosis, number of live births, menstrual cycle disorder, and leiomyoma focality.
  • CONCLUSION: Our findings support that specific genotypes in the progesterone receptor may be involved in tumor growth and metastasis but not in tumor initiation.
  • [MeSH-major] Genetic Predisposition to Disease / epidemiology. Leiomyoma / genetics. Polymorphism, Single Nucleotide. Receptors, Progesterone / genetics. Uterine Neoplasms / genetics

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  • (PMID = 18691687.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Progesterone
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87. Chen SY, Chang DY, Sheu BC, Torng PL, Huang SC, Hsu WC, Chang WC: Laparoscopic-assisted vaginal hysterectomy with in situ morcellation for large uteri. J Minim Invasive Gynecol; 2008 Sep-Oct;15(5):559-65
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • DESIGN: Prospective study (Canadian Task Force classification II-1).
  • PATIENTS: In all, 147 women with myoma or adenomyosis weighing more than 500 g from January 2004 through December 2007 were enrolled.

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  • (PMID = 18657481.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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88. Nezhat C, Lavie O, Hsu S, Watson J, Barnett O, Lemyre M: Robotic-assisted laparoscopic myomectomy compared with standard laparoscopic myomectomy--a retrospective matched control study. Fertil Steril; 2009 Feb;91(2):556-9

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  • The two groups were matched by age, body mass index, parity, previous abdominopelvic surgery, size, number, and location of myomas.
  • It appears that in the hands of a skilled laparoscopic surgeon, the RALM does not offer any major advantage.

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  • (PMID = 18377901.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Godinjak Z, Idrizbegović E: Should diagnostic hysteroscopy be a routine procedure during diagnostic laparoscopy in infertile women? Bosn J Basic Med Sci; 2008 Feb;8(1):44-7
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  • Pelvic adhesions were revealed in 40 (11,11%), and myomas in 42 (11,65%) out of that 31 (8,6%) were revealed by laparoscopy and 11 (3,05%) by hysteroscopy.

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  • (PMID = 18318671.001).
  • [ISSN] 1512-8601
  • [Journal-full-title] Bosnian journal of basic medical sciences
  • [ISO-abbreviation] Bosn J Basic Med Sci
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Bosnia and Herzegovina
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90. Esmaeilzadeh M, Tavakolli A, Safaei A: Recurrent intracardiac leiomyomatosis. Can J Cardiol; 2007 Nov;23(13):1085-6
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An intravenous leiomyoma, a histologically benign smooth muscle tumour, arises from either a uterine myoma or the walls of a uterine vessel, with extension into veins.
  • [MeSH-major] Heart Neoplasms / secondary. Leiomyomatosis / ultrasonography. Smooth Muscle Tumor / ultrasonography. Uterine Neoplasms / ultrasonography
  • [MeSH-minor] Female. Humans. Middle Aged. Neoplasm Recurrence, Local

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  • [Cites] Am J Med. 1980 Sep;69(3):471-5 [7416191.001]
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  • (PMID = 17985013.001).
  • [ISSN] 0828-282X
  • [Journal-full-title] The Canadian journal of cardiology
  • [ISO-abbreviation] Can J Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2651934
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91. Kongnyuy EJ, van den Broek N, Wiysonge CS: A systematic review of randomized controlled trials to reduce hemorrhage during myomectomy for uterine fibroids. Int J Gynaecol Obstet; 2008 Jan;100(1):4-9
Hazardous Substances Data Bank. MISOPROSTOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There was no evidence of effect in blood loss with myoma enucleation by morcellation and oxytocin.

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  • (PMID = 17894936.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0E43V0BB57 / Misoprostol; 11000-17-2 / Vasopressins; 50-56-6 / Oxytocin; Y8335394RO / Bupivacaine
  • [Number-of-references] 25
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92. Sesti F, Capobianco F, Capozzolo T, Pietropolli A, Piccione E: Isobaric gasless laparoscopy versus minilaparotomy in uterine myomectomy: a randomized trial. Surg Endosc; 2008 Apr;22(4):917-23
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A total of 100 patients with symptomatic uterine myomas requiring myomectomy were randomly allocated to the gasless laparoscopy group or the minilaparotomy group.

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  • (PMID = 17705083.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] Germany
  •  go-up   go-down


93. Rossetti A, Sizzi O, Chiarotti F, Florio G: Developments in techniques for laparoscopic myomectomy. JSLS; 2007 Jan-Mar;11(1):34-40
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: We performed 332 single or multiple myomectomies for symptomatic myomas.
  • Most patients (47%) had more than one myoma, with a maximum of 8 per patient (average myomas removed for patients: 2.23, range 1 to 8).
  • Myoma size ranged from 1cm to 20 cm (mean, 60.20+/-SD27.1 mm).
  • Myomas <4cm were removed during myomectomy for larger ones.
  • The dimensions of the myomas removed increased with experience (4.91+/-SD2.2 cm of the earlier cases to 6.76+/-SD2.7 of the latest group, P<0.000).
  • Our results and extremely low conversion rate suggest that laparoscopic myomectomy is a safe and reliable procedure even in the presence of multiple or enlarged myomas.

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  • (PMID = 17651554.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015797
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94. Narang V, Sinha T, Karan SC, Sandhu AS, Sethi GS, Srivastava A, Talwar R, Adlakha N: Ureteroscopy: savior to the gynecologist? Ureteroscopic management of post laparoscopic-assisted vaginal hysterectomy ureterovaginal fistulas. J Minim Invasive Gynecol; 2007 May-Jun;14(3):345-7
MedlinePlus Health Information. consumer health - Ureteral Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Three middle-aged women who underwent LAVH for symptomatic myomas of the uterus presented with ureterovaginal fistulas in the late postoperative period.
  • [MeSH-major] Hysterectomy, Vaginal / adverse effects. Ureteral Diseases / surgery. Ureteroscopy. Urinary Fistula / surgery. Vaginal Fistula / surgery
  • [MeSH-minor] Female. Humans. Iatrogenic Disease. Laparoscopy / adverse effects. Leiomyoma / surgery. Middle Aged. Stents. Ureter / injuries. Ureter / surgery. Uterine Neoplasms / surgery

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  • (PMID = 17478367.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Dingiloglu BS, Gungor T, Ozdal B, Cavkaytar S, Bilge U, Mollamahmutoglu L: Serum leptin levels in women with uterine leiomyomas. Taiwan J Obstet Gynecol; 2007 Mar;46(1):33-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: The purpose of this study was to examine the influence of leptin in women with uterine myoma.
  • MATERIALS AND METHODS: In this study, 38 women with myoma uteri and 30 normal women who applied to the Dr Zekai Tahir Burak Woman Health Research and Education Hospital's gynecology clinic were enrolled.
  • A significant correlation was found between high E2 level and myoma uteri (p = 0.021).
  • So further research is needed to reveal the role of leptin in myoma uteri pathogenesis.

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  • (PMID = 17389186.001).
  • [ISSN] 1875-6263
  • [Journal-full-title] Taiwanese journal of obstetrics & gynecology
  • [ISO-abbreviation] Taiwan J Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CA-125 Antigen; 0 / Hemoglobins; 0 / Hormones; 0 / Leptin
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96. Sośnik H, Jeleń M, Sośnik K, Pomorska M: Liposarcoma of the uterine corpus coexisting with preinvasive cervical cancer--a case report. Pol J Pathol; 2006;57(3):171-3
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Case report of isolated liposarcoma of the uterine corpus coexisting with preinvasive cervix cancer in 71-year-old woman, who 41 years ago underwent the enucleation of the uterine corpus myomas.
  • In tumor histogenesis the malignant transformation of fat cells, which might have been previously transferred to myometrium, was taken into consideration.


97. Botsis D, Papagianni V, Makrakis E, Aravantinos L, Creatsas G: Sonohysterography is superior to transvaginal sonography for the diagnostic approach of irregular uterine bleeding in women of reproductive age. J Clin Ultrasound; 2006 Nov-Dec;34(9):434-9
MedlinePlus Health Information. consumer health - Vaginal Bleeding.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Statistical analysis was performed by calculating the sensitivity, specificity, and positive and negative predictive values of TVS and SHG in diagnosing endometrial polyp, submucous myoma and all endometrial pathologies (polyp, submucous myoma, endometrial hyperplasia, and endometrial carcinoma) with the histopathological report of the tissues obtained by hysteroscopy serving as the end point for the analysis.
  • RESULTS: The sensitivity, specificity, and positive and negative predictive values, respectively of TVS were 61.2%, 90.9%, 85.7%, and 72.5% for diagnosing endometrial polyps; 75.0%, 92.0%, 63.1%, and 95.3% for diagnosing submucous myomas; and 75.0%, 80.6%, 87.9%, and 63.0% for diagnosing any kind of pathology.
  • The corresponding diagnostic values of SHG were 83.7%, 96.4%, 95.3%, and 86.9% for polyps; 87.5%, 98.9%, 93.3%, and 97.8% for submucous myomas; and 88.2%, 91.7%, 95.2%, and 80.5% for any kind of pathology.

  • MedlinePlus Health Information. consumer health - Menstruation.
  • MedlinePlus Health Information. consumer health - Ultrasound.
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  • [Copyright] Copyright 2006 Wiley Periodicals, Inc.
  • (PMID = 17109401.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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98. Klatsky PC, Lane DE, Ryan IP, Fujimoto VY: The effect of fibroids without cavity involvement on ART outcomes independent of ovarian age. Hum Reprod; 2007 Feb;22(2):521-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Neither the location (subserosal versus intramural) and the presence of multiple myomas nor the size of the myomas affected outcomes.

  • MedlinePlus Health Information. consumer health - Uterine Cancer.
  • MedlinePlus Health Information. consumer health - Uterine Fibroids.
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  • [ErratumIn] Hum Reprod. 2007 Apr;22(4):1195
  • (PMID = 16997932.001).
  • [ISSN] 0268-1161
  • [Journal-full-title] Human reproduction (Oxford, England)
  • [ISO-abbreviation] Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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99. Maradin M, Fumić K, Hansikova H, Tesarova M, Wenchich L, Dorner S, Sarnavka V, Zeman J, Barić I: Fumaric aciduria: mild phenotype in a 8-year-old girl with novel mutations. J Inherit Metab Dis; 2006 Oct;29(5):683
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fumaric aciduria is a rare, autosomal recessive disorder caused by deficient activity of fumarate hydratase (FH).
  • Our patient had a relatively mild phenotype, a previously not reported genotype and familial tumour predisposition.
  • The mother and grandmother had uterine myomas.

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  • (PMID = 16972175.001).
  • [ISSN] 0141-8955
  • [Journal-full-title] Journal of inherited metabolic disease
  • [ISO-abbreviation] J. Inherit. Metab. Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] EC 4.2.1.2 / Fumarate Hydratase
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100. Kunz J, Bleisch J: [Uterine leiomyoma as cause of erythrocytosis]. Praxis (Bern 1994); 2006 Aug 16;95(33):1227-31
MedlinePlus Health Information. consumer health - Uterine Fibroids.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myoma-induced erythrocytosis is a rare clinical picture which is probably largely misunderstood.
  • Myomatous erythrocytosis syndrome (MES) can be the explanation of normal haematological parameters in patients with myoma-related hypermenorrhoea and menorrhagia.

  • Genetic Alliance. consumer health - Uterine Fibroid.
  • MedlinePlus Health Information. consumer health - Uterine Cancer.
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  • (PMID = 16939124.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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