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1. Ronchetti D, Lionetti M, Mosca L, Agnelli L, Andronache A, Fabris S, Deliliers GL, Neri A: An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma. BMC Med Genomics; 2008;1:37
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  • Conventional statistics were used to test correlations for significance.
  • RESULTS: We identified transcripts specific to six miRNA host genes (CCPG1, GULP1, EVL, TACSTD1, MEST, and TNIK) whose average changes in expression varied at least 2-fold from the mean of the examined dataset.
  • We evaluated the expression levels of the corresponding intronic miRNAs and identified a significant correlation between the expression levels of MEST, EVL, and GULP1 and those of the corresponding miRNAs miR-335, miR-342-3p, and miR-561, respectively.
  • The predicted putative miRNA targets and the transcriptional profiles associated with the primary tumors suggest that MEST/miR-335 and EVL/miR-342-3p may play a role in plasma cell homing and/or interactions with the bone marrow microenvironment.


2. Chu LC, Hruban RH, Horton KM, Fishman EK: Mixed epithelial and stromal tumor of the kidney: radiologic-pathologic correlation. Radiographics; 2010 Oct;30(6):1541-51
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  • [Title] Mixed epithelial and stromal tumor of the kidney: radiologic-pathologic correlation.
  • Mixed epithelial and stromal tumor (MEST) of the kidney is a rare, typically benign lesion that occurs predominantly in perimenopausal women.
  • MEST may mimic a variety of benign and malignant renal lesions, such as adult cystic nephroma, complex renal cyst, and cystic renal cell carcinoma.
  • The preoperative diagnosis of MEST can be problematic, and most cases are treated surgically.
  • However, CT with two-dimensional multiplanar reformation and three-dimensional volume rendering helps define the diagnostic features of MEST and can assist in surgical planning.
  • [MeSH-major] Kidney Neoplasms / radiography. Neoplasms, Complex and Mixed / diagnosis. Neoplasms, Glandular and Epithelial / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Imaging, Three-Dimensional. Male. Middle Aged

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  • [Copyright] © RSNA, 2010.
  • (PMID = 21071374.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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3. Rossignol S, Steunou V, Chalas C, Kerjean A, Rigolet M, Viegas-Pequignot E, Jouannet P, Le Bouc Y, Gicquel C: The epigenetic imprinting defect of patients with Beckwith-Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region. J Med Genet; 2006 Dec;43(12):902-7
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  • AIM: To analyse the methylation status of various imprinted genes (IGF2R gene at 6q26, PEG1/MEST at 7q32, KCNQ1OT1 and H19 at 11p15.5, and SNRPN at 15q11-13) in 40 patients with BWS showing a loss of methylation at KCNQ1OT1 (11 patients with BWS born after the use of ART and 29 patients with BWS conceived naturally).

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  • [Cites] Hum Mol Genet. 2000 Sep 1;9(14):2183-7 [10958657.001]
  • [Cites] Hum Genet. 2006 Mar;119(1-2):179-84 [16402210.001]
  • [Cites] Nat Rev Genet. 2001 Jan;2(1):21-32 [11253064.001]
  • [Cites] Biochim Biophys Acta. 2001 Mar 19;1518(1-2):137-44 [11267669.001]
  • [Cites] Nucleic Acids Res. 2001 Jul 1;29(13):E65-5 [11433041.001]
  • [Cites] Eur J Hum Genet. 2001 Jun;9(6):409-18 [11436121.001]
  • [Cites] Hum Mol Genet. 2002 May 15;11(11):1317-25 [12019213.001]
  • [Cites] Am J Hum Genet. 2002 Jul;71(1):162-4 [12016591.001]
  • [Cites] Am J Hum Genet. 2003 Jan;72(1):156-60 [12439823.001]
  • [Cites] J Med Genet. 2003 Jan;40(1):62-4 [12525545.001]
  • [Cites] Am J Hum Genet. 2003 Jan;72(1):218-9 [12549484.001]
  • [Cites] Am J Hum Genet. 2003 May;72(5):1338-41 [12772698.001]
  • [Cites] Philos Trans R Soc Lond B Biol Sci. 2003 Aug 29;358(1436):1411-5 [14511489.001]
  • [Cites] Hum Mol Genet. 2003 Nov 15;12(22):2873-9 [14500540.001]
  • [Cites] J Med Genet. 2004 Jan;41(1):e4 [14729844.001]
  • [Cites] Hum Mol Genet. 2004 Apr 15;13(8):839-49 [14998934.001]
  • [Cites] Development. 2004 Aug;131(15):3727-35 [15240554.001]
  • [Cites] Am J Hum Genet. 2004 Sep;75(3):526-8 [15284956.001]
  • [Cites] Nat Genet. 2004 Sep;36(9):958-60 [15314640.001]
  • [Cites] Am J Hum Genet. 2004 Nov;75(5):844-9 [15372379.001]
  • [Cites] Biochem Biophys Res Commun. 1993 Dec 15;197(2):747-54 [8267611.001]
  • [Cites] Hum Mol Genet. 1995 Oct;4(10):1945-52 [8595419.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7811-5 [8755558.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Hum Mutat. 2005 Jan;25(1):56-63 [15580563.001]
  • [Cites] Fertil Steril. 2005 Feb;83(2):349-54 [15705373.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4085-90 [15743916.001]
  • [Cites] J Med Genet. 2005 Apr;42(4):289-91 [15805153.001]
  • [Cites] Nucleic Acids Res. 2005;33(8):2650-60 [15888726.001]
  • [Cites] Hum Mol Genet. 2006 Feb 15;15(4):589-98 [16403808.001]
  • [Cites] Nat Genet. 2001 Feb;27(2):153-4 [11175780.001]
  • (PMID = 16825435.001).
  • [ISSN] 1468-6244
  • [Journal-full-title] Journal of medical genetics
  • [ISO-abbreviation] J. Med. Genet.
  • [Language] eng
  • [Databank-accession-numbers] OMIM/ 105830/ 130650/ 601410
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Autoantigens; 0 / KCNQ1OT1 protein, human; 0 / Membrane Proteins; 0 / Potassium Channels, Voltage-Gated; 0 / Proteins; 0 / Receptor, IGF Type 2; 0 / Ribonucleoproteins, Small Nuclear; 0 / SNRPN protein, human; 0 / mesoderm specific transcript protein; 0 / snRNP Core Proteins; 9007-49-2 / DNA
  • [Other-IDs] NLM/ PMC2563199
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4. Bergström MA, Luthman K, Karlberg AT: Metabolic epoxidation of an alpha,beta-unsaturated oxime generates sensitizers of extreme potency. Are nitroso intermediates responsible? Chem Res Toxicol; 2007 Jun;20(6):927-36
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  • The alpha,beta-epoxy oxime metabolites were found to be sensitizers of extreme potency in the local lymph node assay and highly reactive toward nucleophilic amino acids and a model peptide.
  • One of the two diastereomeric epoxy metabolites also elicited an allergic reaction in mice sensitized to 1, in the mouse ear swelling test.
  • [MeSH-minor] Acetylcysteine / analogs & derivatives. Acetylcysteine / metabolism. Acetylcysteine / pharmacology. Animals. Dose-Response Relationship, Drug. Female. Glutathione / analogs & derivatives. Glutathione / chemistry. Glutathione / metabolism. Glutathione / pharmacology. Humans. Hydrogen-Ion Concentration. Lymph Nodes / drug effects. Lymph Nodes / pathology. Mice. Mice, Inbred CBA. Microsomes, Liver / drug effects. Microsomes, Liver / metabolism. Molecular Structure. Oligopeptides / chemistry. Oligopeptides / metabolism. Oligopeptides / pharmacology. Oxidation-Reduction / drug effects. Spectrophotometry, Ultraviolet. Stereoisomerism. Toxicity Tests / methods

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  • (PMID = 17511479.001).
  • [ISSN] 0893-228X
  • [Journal-full-title] Chemical research in toxicology
  • [ISO-abbreviation] Chem. Res. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Allergens; 0 / Epoxy Compounds; 0 / Nitroso Compounds; 0 / Oligopeptides; 0 / Oximes; 97451-46-2 / glutathione monoisopropyl ester; GAN16C9B8O / Glutathione; WYQ7N0BPYC / Acetylcysteine
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5. Anckaert E, Romero S, Adriaenssens T, Smitz J: Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment. Biol Reprod; 2010 Sep;83(3):377-86
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  • [Title] Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment.
  • We previously demonstrated establishment of normal imprinting at four key imprinted genes in mouse metaphase II oocytes after in vitro follicle culture.
  • The aim of the present study was to examine the effect of low methyl donor (methionine, vitamin B(12), folic acid, choline, and vitamin B(6)) levels during follicle culture on acquisition of DNA methylation at imprinted genes in mouse oocytes.
  • DMRs of Snrpn, Igf2r, and H19 showed no alteration in DNA methylation, but at Mest DMR in PB oocytes, we found a significant reduction in DNA methylation compared to that in control follicle culture (DNA methylation, 89.9% and 98.2%, respectively; P = 0.0014).

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  • (PMID = 20393167.001).
  • [ISSN] 1529-7268
  • [Journal-full-title] Biology of reproduction
  • [ISO-abbreviation] Biol. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Culture Media; 0 / H19 long non-coding RNA; 0 / RNA, Long Noncoding; 0 / RNA, Untranslated; 0 / Receptor, IGF Type 2; 0 / snRNP Core Proteins; 8059-24-3 / Vitamin B 6; 935E97BOY8 / Folic Acid; AE28F7PNPL / Methionine; N91BDP6H0X / Choline; P6YC3EG204 / Vitamin B 12
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6. Mohanty SK, Parwani AV: Mixed epithelial and stromal tumors of the kidney: an overview. Arch Pathol Lab Med; 2009 Sep;133(9):1483-6
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  • [Title] Mixed epithelial and stromal tumors of the kidney: an overview.
  • Mixed epithelial and stromal tumor of the kidney is a recently recognized distinct neoplasm that should be distinguished from other renal neoplasms.
  • Histopathologically, these tumors reveal biphasic growth pattern comprising mesenchymal and epithelial elements with characteristic estrogen and progesterone receptor immunoreactive mesenchyme reminiscent of ovarian stroma.
  • Malignant transformation, recurrence, and metastasis are rare; however, recently a few cases of malignant mixed epithelial and stromal tumors have been reported in the literature.
  • This article provides a brief overview of the current knowledge of mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Epithelial Cells / pathology. Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Chromosomes, Human, Pair 1. Chromosomes, Human, Pair 19. Diagnosis, Differential. Female. Fibroma / diagnosis. Humans. Male. Middle Aged. Nephroma, Mesoblastic / diagnosis. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Stromal Cells / metabolism. Stromal Cells / pathology. Translocation, Genetic. Young Adult

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  • (PMID = 19722760.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
  • [Number-of-references] 28
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7. Meng LH, Xiao SQ, Huang XF, Zhou Y, Xu BS: [A study on bisulfite sequencing method for methylation status of imprinted genes in single human oocytes]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2008 Jun;25(3):289-92
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  • METHODS: Single superovulated immature human oocyte was embedded into low melting point agarose, followed by bisulfite treatment and polymerase chain reaction (PCR) amplification of the H19 and MEST genes.

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  • (PMID = 18543218.001).
  • [ISSN] 1003-9406
  • [Journal-full-title] Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
  • [ISO-abbreviation] Zhonghua Yi Xue Yi Chuan Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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8. Nieoczym D, Łuszczki JJ, Czuczwar SJ, Wlaź P: Effect of sildenafil on the anticonvulsant action of classical and second-generation antiepileptic drugs in maximal electroshock-induced seizures in mice. Epilepsia; 2010 Aug;51(8):1552-9
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  • METHODS: Two electroconvulsive tests were used: maximal electroshock seizure threshold (MEST) and maximal electroshock seizure (MES) tests in mice.
  • Acute adverse effects of the studied combinations were investigated in the chimney test, step-through passive avoidance task, and grip-strength test.
  • It also increased the anticonvulsant activity of CBZ, VPA, and TPM in the MES test, whereas the activity of the remaining AEDs was not significantly changed.

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  • [Copyright] Wiley Periodicals, Inc. © 2010 International League Against Epilepsy.
  • (PMID = 20067503.001).
  • [ISSN] 1528-1167
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Phosphodiesterase Inhibitors; 0 / Piperazines; 0 / Purines; 0 / Sulfones; BW9B0ZE037 / Sildenafil Citrate
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9. Bentow JJ, Thuangtong R, Iwasaki J, French SW, Kolodney MS: A light-emitting mouse to image skin inflammation. Dermatitis; 2009 May-Jun;20(3):142-8
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  • [Title] A light-emitting mouse to image skin inflammation.
  • BACKGROUND: The mouse ear swelling test is a well-accepted method for quantitating the inflammatory response to contact irritants and sensitizing agents.
  • METHODS: We bred a transgenic bioluminescent mouse that emits light proportional to cutaneous infiltration of inflammatory cells.
  • A mouse strain expressing cyclization recombinase enzyme (cre) recombinase exclusively in myeloid cells was crossed with a reporter strain containing an inactivated form of the luciferase gene.
  • Light emission and swelling from the inflamed ear was quantitated and compared to the contralateral ear.
  • In sensitized mice challenged with squaric acid, luminescence increased about 2.2-fold while swelling increased about 1.5-fold.
  • [MeSH-minor] Animals. Ear, External. Edema / chemically induced. Edema / complications. Irritants. Luminescent Proteins. Mice. Mice, Transgenic

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  • (PMID = 19470300.001).
  • [ISSN] 2162-5220
  • [Journal-full-title] Dermatitis : contact, atopic, occupational, drug
  • [ISO-abbreviation] Dermatitis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Antigens; 0 / Irritants; 0 / Luminescent Proteins
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10. Kwon JE, Kang JH, Kwon GY: Mixed epithelial and stromal tumor of the kidney: a case report. J Korean Med Sci; 2007 Feb;22(1):159-62
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  • [Title] Mixed epithelial and stromal tumor of the kidney: a case report.
  • The descriptive term "mixed epithelial and stromal tumor of the kidney" was recently proposed for a group of renal tumors characterized histologically by a mixture of stromal and epithelial proliferation.
  • It is a rare benign neoplasm of the kidney which has been reported under various names such as adult type mesoblastic nephroma or others.
  • We report a case of mixed epithelial and stromal tumor in a 47 yr old female patient presenting as a partly cystic and partly solid renal mass.
  • Microscopically, the tumor exhibited spindle cell component in solid portion and epithelial proliferation around microcystic areas.
  • Immunoreactive profiles and ultrastructural examination suggested myofibroblastic nature of the stromal cells.
  • We believe this case exemplifies a unique adult renal tumor displaying both epithelial and stromal neoplastic component and has a few unusual features worthy of attention.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Nephroma, Mesoblastic / pathology

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  • [Cites] Pathol Res Pract. 2000;196(2):135-9 [10707372.001]
  • [Cites] Histopathology. 1999 Jul;35(1):65-73 [10383716.001]
  • [Cites] Arch Pathol Lab Med. 2001 Jun;125(6):751-8 [11371226.001]
  • [Cites] Hum Pathol. 2001 May;32(5):513-20 [11381370.001]
  • [Cites] Am J Surg Pathol. 2001 Sep;25(9):1194-9 [11688580.001]
  • [Cites] Histopathology. 2004 Mar;44(3):302-4 [14987239.001]
  • [Cites] J Urol. 1973 Oct;110(4):380-3 [4355052.001]
  • [Cites] J Urol. 1987 Aug;138(2):397-9 [3037125.001]
  • [Cites] Arch Pathol Lab Med. 1990 May;114(5):533-5 [2185715.001]
  • [Cites] Am J Surg Pathol. 1992 Apr;16(4):325-34 [1373578.001]
  • [Cites] Am J Surg Pathol. 1993 Oct;17(10):1029-38 [8396855.001]
  • [Cites] Am J Surg Pathol. 1993 Nov;17(11):1169-75 [8214262.001]
  • [Cites] Cancer. 1998 Jun 15;82(12):2427-33 [9635536.001]
  • [Cites] Am J Surg Pathol. 1998 Jul;22(7):827-39 [9669345.001]
  • [Cites] Pathol Res Pract. 1998;194(6):445-8 [9689654.001]
  • [Cites] Am J Surg Pathol. 2000 Jul;24(7):958-70 [10895818.001]
  • (PMID = 17297273.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2693557
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11. Velmahos GC, Petrone P, Chan LS, Hanks SE, Brown CV, Demetriades D: Electrostimulation for the prevention of deep venous thrombosis in patients with major trauma: a prospective randomized study. Surgery; 2005 May;137(5):493-8
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  • Muscle electrostimulation (MEST) has been used over the years with mixed-but predominantly encouraging-results for a variety of conditions, including prevention of deep venous thrombosis (DVT).
  • METHODS: Trauma patients with Injury Severity Score higher than 9 who were admitted to the intensive care unit and had a contraindication for prophylactic heparinization were randomized to groups MEST and control.
  • MEST patients received 30-minute MEST sessions twice daily for 7 to 14 days.
  • RESULTS: After exclusions, 26 MEST and 21 control patients completed the study and received outcome evaluation by venography (25) or duplex (22).
  • Three patients in each group developed proximal DVT (11.5% vs 14%, P = .79), and an additional 4 (15%) MEST group and 3 (14%) control group patients developed peripheral DVT ( P = .96).
  • CONCLUSIONS: MEST was not effective in decreasing DVT rates in major trauma patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Injury Severity Score. Leg / blood supply. Leg / radiography. Leg / ultrasonography. Male. Middle Aged. Muscle, Skeletal. Prospective Studies. Treatment Failure

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  • (PMID = 15855919.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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12. Muller S, Oevermann A, Wenker C, Altermatt HJ, Robert N: A mixed epithelial and stromal tumor of the kidney in a ringtail lemur (Lemur catta). Vet Pathol; 2007 Mar;44(2):243-6
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  • [Title] A mixed epithelial and stromal tumor of the kidney in a ringtail lemur (Lemur catta).
  • This report describes a mixed epithelial and stromal tumor of the kidney (MESTK) in a 14.5-year-old female ringtail lemur.
  • The well-demarcated, solid, and cystic mass was located in the pelvis of the left kidney and consisted histologically of both epithelial and mesenchymal components.
  • Neither the mesenchymal nor the epithelial parts showed significant nuclear atypia or mitotic figures.
  • In humans this tumor affects predominantly perimenopausal women and can express estrogen and progesterone receptors.
  • However, neither estrogen nor progesterone receptors could be identified by immunohistochemistry in the tumor of the present ringtail lemur.
  • [MeSH-major] Kidney Neoplasms / veterinary. Lemur. Neoplasms, Glandular and Epithelial / veterinary. Primate Diseases / pathology
  • [MeSH-minor] Animals. Animals, Zoo. Fatal Outcome. Female. Immunohistochemistry / veterinary. Stromal Cells / pathology

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  • (PMID = 17317808.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. da Silva CS, Adad SJ, Saldanha JC, Cançado CG, Bachi C, Murta EF: Synchronous sertoli cell and serous cystadenoma tumors of the ovaries with mixed epithelial and stromal tumor of the kidney: a case report. Clin Genitourin Cancer; 2007 Jun;5(5):338-40
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  • [Title] Synchronous sertoli cell and serous cystadenoma tumors of the ovaries with mixed epithelial and stromal tumor of the kidney: a case report.
  • We present a rare case of a 68-year-old postmenopausal woman with a mobile, hard, and painless pelvic abdominal mass that was palpated to the umbilical scar.
  • Ultrasonography demonstrated a solid mass in the upper pole of the right kidney and a predominantly solid pelvic abdominal mass.
  • The patient underwent laparotomy on the renal tumor, which was thought to have a probable ovarian metastasis.
  • Immunohistochemical and histopathologic assessment identified a right ovarian Sertoli cell tumor, a left ovarian serous cystadenoma, and a mixed epithelial-stromal tumor in the kidney with positive hormonal receptor.
  • Because our patient had an ovarian neoplasm producing steroids and a kidney tumor expressing hormonal receptors, the hypothesis of possible endocrine dependence in the pathogenesis of mixed epithelial stromal tumor is reinforced.
  • [MeSH-major] Cystadenoma, Serous / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology. Ovarian Neoplasms / pathology. Sertoli Cell Tumor / pathology. Sex Cord-Gonadal Stromal Tumors / pathology

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  • (PMID = 17645832.001).
  • [ISSN] 1558-7673
  • [Journal-full-title] Clinical genitourinary cancer
  • [ISO-abbreviation] Clin Genitourin Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Hahn Y, Yang SK, Chung JH: Structure and expression of the zebrafish mest gene, an ortholog of mammalian imprinted gene PEG1/MEST. Biochim Biophys Acta; 2005 Nov 10;1731(2):125-32
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  • [Title] Structure and expression of the zebrafish mest gene, an ortholog of mammalian imprinted gene PEG1/MEST.
  • PEG1/MEST is a paternally expressed gene in placental mammals.
  • Here, we report identification of zebrafish (Danio rerio) gene mest, an ortholog of mammalian PEG1/MEST.
  • Zebrafish mest encodes a polypeptide of 344 amino acids and shows a significant similarity to mammalian orthologs.
  • Zebrafish mest is present as a single copy in the zebrafish genome and is closely linked to copg2 as in mammals.
  • It is notable that 10 of 11 intron positions in mest are conserved among mammalian PEG1/MEST genes, indicating that the genomic organization and linkage between mest and copg2 loci was established in ancient vertebrates.
  • Zebrafish mest is expressed in blastula, segmentation, and larval stages, exhibiting gradually increased expression as the development proceeds.
  • We also observed one-codon alternative splicing involving an alternative usage of the two consecutive splice acceptors of intron 1, generating two protein isoforms with different lengths of a single amino acid.

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  • (PMID = 16263186.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Codon; 0 / DNA, Complementary; 0 / Proteins; 0 / mesoderm specific transcript protein
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15. XU C, SU L, ZHOU Q, LI C, ZHAO S: Imprinting analysis of the porcine MEST gene in 75 and 90 day placentas and prenatal tissues. Acta Biochim Biophys Sin (Shanghai); 2007 Aug;39(8):633-9
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  • [Title] Imprinting analysis of the porcine MEST gene in 75 and 90 day placentas and prenatal tissues.
  • Mouse mesoderm-specific transcript (MEST) has been identified as an imprinted gene and mapped to an imprinted region of mouse chromosome 6 (MMU6).
  • It plays essential roles in embryonic and placental growth, and it is required for maternal behavior in adult female mouse.
  • Here, we isolated the porcine MEST gene and detected a single nucleotide polymorphism in the 3 -untranslated region.
  • The results indicate that MEST was imprinted in placentas on days 75 and 90 of gestation as well as in the 75 d fetal heart, muscle, kidney, lung and liver.

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  • (PMID = 17687499.001).
  • [ISSN] 1672-9145
  • [Journal-full-title] Acta biochimica et biophysica Sinica
  • [ISO-abbreviation] Acta Biochim. Biophys. Sin. (Shanghai)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / DNA, Complementary; 0 / Proteins; 0 / mesoderm specific transcript protein
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16. Apostolidou S, Abu-Amero S, O'Donoghue K, Frost J, Olafsdottir O, Chavele KM, Whittaker JC, Loughna P, Stanier P, Moore GE: Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight. J Mol Med (Berl); 2007 Apr;85(4):379-87
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  • The expression levels of four imprinted genes, the paternally expressed insulin growth factor 2 (IGF2), the mesoderm-specific transcript isoform 1 (MEST); the maternally expressed pleckstrin homology-like domain, family A, member 2 (PHLDA2); and the polymorphically imprinted insulin-like growth factor 2 (IGF2R) gene are all known to have roles in fetal growth and were studied in the placentae of 200 white European, normal term babies.
  • The quantitative expression analysis with real-time PCR showed the maternally expressing PHLDA2 but not the paternally expressing IGF2 and MEST, nor the polymorphic maternally expressing IGF2R placental levels to have a statistically significant effect on birth weight.

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  • [Cites] Genesis. 2004 May;39(1):65-72 [15124229.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 May 25;101(21):8204-8 [15150410.001]
  • [Cites] Mol Cell Biol. 2000 May;20(9):3308-15 [10757814.001]
  • [Cites] Acta Paediatr. 1997 Aug;86(8):826-33 [9307161.001]
  • [Cites] Nat Genet. 1993 May;4(1):98-101 [8099843.001]
  • [Cites] Immunity. 1996 Jun;4(6):583-91 [8673705.001]
  • [Cites] Placenta. 2006 Feb-Mar;27(2-3):119-26 [16338457.001]
  • [Cites] Mech Dev. 2004 Oct;121(10):1199-210 [15327781.001]
  • [Cites] Biochem Biophys Res Commun. 1998 Apr 7;245(1):272-7 [9535821.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Nov;85(11):4266-9 [11095465.001]
  • [Cites] Am J Med Genet. 2001 Dec 1;104(3):225-31 [11754049.001]
  • [Cites] Exp Cell Res. 1999 Apr 10;248(1):18-24 [10094809.001]
  • [Cites] Nutrition. 2002 Jul-Aug;18(7-8):604-8 [12093439.001]
  • [Cites] Genes Dev. 1994 Dec 15;8(24):2953-63 [8001817.001]
  • [Cites] Nature. 1990 May 3;345(6270):78-80 [2330056.001]
  • [Cites] Nat Genet. 1993 Sep;5(1):74-8 [8220428.001]
  • [Cites] Trends Genet. 1991 Feb;7(2):45-9 [2035190.001]
  • [Cites] J Cell Physiol. 2000 Jan;182(1):62-8 [10567917.001]
  • [Cites] Hum Mol Genet. 2006 Apr 15;15(8):1259-69 [16531418.001]
  • [Cites] Placenta. 2006 Jun-Jul;27(6-7):540-9 [16125225.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6623-8 [16614068.001]
  • [Cites] Cancer Res. 2000 Mar 15;60(6):1521-5 [10749116.001]
  • [Cites] Cytogenet Genome Res. 2006;113(1-4):262-70 [16575189.001]
  • [Cites] Genes Dev. 1997 Dec 1;11(23):3128-42 [9389646.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 May 28;99(11):7490-5 [12032310.001]
  • [Cites] Development. 1989 Jul;106(3):543-54 [2598824.001]
  • [Cites] Nature. 2002 Jun 27;417(6892):945-8 [12087403.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Genome Res. 2000 Nov;10(11):1697-710 [11076855.001]
  • [Cites] Hum Mol Genet. 2002 Jun 1;11(12):1449-53 [12023987.001]
  • [Cites] Jpn J Hum Genet. 1997 Mar;42(1):205-11 [9184000.001]
  • [Cites] Placenta. 2003 Sep-Oct;24(8-9):835-42 [13129680.001]
  • [Cites] Mol Hum Reprod. 2000 Nov;6(11):1019-25 [11044465.001]
  • [Cites] Am J Hum Genet. 2000 Jan;66(1):309-12 [10631159.001]
  • (PMID = 17180344.001).
  • [ISSN] 0946-2716
  • [Journal-full-title] Journal of molecular medicine (Berlin, Germany)
  • [ISO-abbreviation] J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Nuclear Proteins; 0 / RNA, Messenger; 0 / TSSC3 protein
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17. Cheng Y, Wang K, Kellam LD, Lee YS, Liang CG, Han Z, Mtango NR, Latham KE: Effects of ooplasm manipulation on DNA methylation and growth of progeny in mice. Biol Reprod; 2009 Mar;80(3):464-72
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  • This study investigates the possible epigenetic effects of ooplasm manipulation methods on postnatal growth and development using a mouse genetic model, with particular emphasis on the possible effects of intergenotype manipulations.
  • No GVT-associated changes were observed in DNA methylation of the Mup1, Rasgrf1, H19, Snrpn, or Peg3 genes, nor any difference in expression of the imprinted Rasgrf1, Igf2r, or Mest genes.

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  • [Cites] Hum Reprod. 2000 Dec;15 Suppl 5:68-86 [11263539.001]
  • [Cites] Hum Reprod Update. 2008 Nov-Dec;14(6):669-78 [18772267.001]
  • [Cites] Mech Dev. 2001 May;103(1-2):35-47 [11335110.001]
  • [Cites] Endocr Rev. 2001 Dec;22(6):818-35 [11739335.001]
  • [Cites] Dev Biol. 2001 Dec 15;240(2):585-98 [11784085.001]
  • [Cites] Dev Biol. 2002 Jan 1;241(1):172-82 [11784103.001]
  • [Cites] Hum Reprod. 2002 Apr;17(4):850-2 [11925371.001]
  • [Cites] Genomics. 2002 Apr;79(4):530-8 [11944985.001]
  • [Cites] Am J Hum Genet. 2002 Jul;71(1):162-4 [12016591.001]
  • [Cites] Hum Reprod. 2002 Oct;17(10):2678-85 [12351548.001]
  • [Cites] Am J Hum Genet. 2003 Jan;72(1):156-60 [12439823.001]
  • [Cites] J Med Genet. 2003 Jan;40(1):62-4 [12525545.001]
  • [Cites] Am J Hum Genet. 2003 Jan;72(1):218-9 [12549484.001]
  • [Cites] Hum Reprod. 2003 Sep;18(9):1903-7 [12923147.001]
  • [Cites] Mamm Genome. 2003 Aug;14(8):495-505 [12925882.001]
  • [Cites] Curr Biol. 2000 Apr 20;10(8):475-8 [10801417.001]
  • [Cites] Biol Reprod. 2000 Jun;62(6):1526-35 [10819752.001]
  • [Cites] Biol Reprod. 2001 Feb;64(2):696-705 [11159375.001]
  • [Cites] Hum Reprod. 2001 Mar;16(3):513-6 [11228222.001]
  • [Cites] Reprod Biomed Online. 2004 Jan;8(1):75-80 [14759291.001]
  • [Cites] Biol Reprod. 2004 Apr;70(4):1162-70 [14681201.001]
  • [Cites] Hum Reprod. 2004 Apr;19(4):975-81 [15016785.001]
  • [Cites] Nature. 1984 Apr 5-11;308(5959):548-50 [6709062.001]
  • [Cites] Cell. 1984 May;37(1):179-83 [6722870.001]
  • [Cites] Nature. 1984 Sep 27-Oct 3;311(5984):374-6 [6482961.001]
  • [Cites] J Embryol Exp Morphol. 1985 Dec;90:267-85 [3834032.001]
  • [Cites] Genes Dev. 1988 Apr;2(4):453-61 [3286373.001]
  • [Cites] J Reprod Fertil. 1989 Jul;86(2):679-88 [2760894.001]
  • [Cites] Development. 1991 Oct;113(2):561-8 [1782866.001]
  • [Cites] Proc Soc Exp Biol Med. 1992 Sep;200(4):536-41 [1508946.001]
  • [Cites] Mutat Res. 1992 Dec;296(1-2):69-88 [1279409.001]
  • [Cites] Development. 1993 Nov;119(3):933-42 [8187648.001]
  • [Cites] Biol Reprod. 1994 May;50(5):1027-33 [8025158.001]
  • [Cites] Nucleic Acids Res. 1994 Aug 11;22(15):2990-7 [8065911.001]
  • [Cites] Biol Reprod. 1995 Apr;52(4):709-20 [7779992.001]
  • [Cites] Nat Genet. 1996 May;13(1):91-4 [8673112.001]
  • [Cites] Reprod Fertil Dev. 1996;8(6):975-80 [8896032.001]
  • [Cites] Hum Reprod. 1996 Oct;11(10):2217-22 [8943533.001]
  • [Cites] Nucleic Acids Res. 1996 Dec 15;24(24):5064-6 [9016686.001]
  • [Cites] Curr Biol. 1997 Apr 1;7(4):277-80 [9094308.001]
  • [Cites] Development. 1998 Mar;125(5):929-35 [9449675.001]
  • [Cites] Hum Reprod. 1998 Jan;13(1):154-60 [9512249.001]
  • [Cites] Mol Hum Reprod. 1998 Mar;4(3):269-80 [9570273.001]
  • [Cites] Mol Cell Biol. 1998 Jul;18(7):4149-56 [9632799.001]
  • [Cites] Dev Genet. 1998;23(2):111-8 [9770268.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Fertil Steril. 1999 Apr;71(4):726-31 [10202887.001]
  • [Cites] Hum Reprod. 1999 May;14(5):1312-7 [10325284.001]
  • [Cites] Hum Reprod. 1999 Sep;14(9):2357-61 [10469710.001]
  • [Cites] Genomics. 2004 Dec;84(6):952-60 [15533712.001]
  • [Cites] Biol Reprod. 2005 Mar;72(3):612-8 [15537860.001]
  • [Cites] Hum Reprod. 2005 Jul;20(7):1958-68 [15817588.001]
  • [Cites] Ann N Y Acad Sci. 2005 May;1042:177-85 [15965061.001]
  • [Cites] J Am Soc Nephrol. 2005 Oct;16(10):2913-9 [16093454.001]
  • [Cites] Zygote. 2005 Nov;13(4):317-23 [16388700.001]
  • [Cites] Hypertension. 2007 Jun;49(6):1415-21 [17452506.001]
  • [Cites] Soc Reprod Fertil Suppl. 2007;63:153-8 [17566270.001]
  • [Cites] Int J Obes (Lond). 2007 Sep;31(9):1392-9 [17356523.001]
  • [Cites] Hum Mol Genet. 2008 Jan 1;17(1):1-14 [17901045.001]
  • [Cites] Kidney Int. 2008 Jul;74(2):187-95 [18432184.001]
  • [Cites] FASEB J. 2008 Aug;22(8):2676-89 [18390925.001]
  • [Cites] Biol Reprod. 2008 Oct;79(4):638-48 [18562704.001]
  • [Cites] Hum Reprod. 2001 Apr;16(4):730-6 [11278226.001]
  • (PMID = 19073997.001).
  • [ISSN] 0006-3363
  • [Journal-full-title] Biology of reproduction
  • [ISO-abbreviation] Biol. Reprod.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / R24 RR015253; United States / NCRR NIH HHS / RR / R01 RR18907; United States / NICHD NIH HHS / HD / R01 HD041440; United States / NCRR NIH HHS / RR / R24 RR15253; United States / NICHD NIH HHS / HD / R01 HD41440; United States / NCRR NIH HHS / RR / R01 RR018907
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Kruppel-Like Transcription Factors; 0 / Peg3 protein, mouse; 0 / Proteins; 0 / Rasgrf1 protein, mouse; 0 / major urinary proteins; 0 / ras-GRF1
  • [Other-IDs] NLM/ PMC2805397
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18. Imamura T, Kerjean A, Heams T, Kupiec JJ, Thenevin C, Pàldi A: Dynamic CpG and non-CpG methylation of the Peg1/Mest gene in the mouse oocyte and preimplantation embryo. J Biol Chem; 2005 May 20;280(20):20171-5
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  • [Title] Dynamic CpG and non-CpG methylation of the Peg1/Mest gene in the mouse oocyte and preimplantation embryo.
  • In somatic tissues, the CpG island of the imprinted Peg1/Mest gene is methylated on the maternal allele.
  • After short in vitro culture, Peg1/Mest became hypermethylated, whereas prolonged in vitro culture resulted in demethylation in a fraction of oocytes.

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  • (PMID = 15778220.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proteins; 0 / mesoderm specific transcript protein; 9007-49-2 / DNA
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19. Picken MM, Fresco R: Mixed epithelial and stromal tumor of the kidney: preliminary immunohistochemical and electron microscopic studies of the epithelial component. Ultrastruct Pathol; 2005 May-Aug;29(3-4):283-6
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  • [Title] Mixed epithelial and stromal tumor of the kidney: preliminary immunohistochemical and electron microscopic studies of the epithelial component.
  • Mixed epithelial and stromal tumor of the kidney is a rare biphasic tumor composed of cysts and tubules embedded in the spindle cell stroma.
  • Although the histogenesis of this tumor is unknown, it has been proposed that both components of the tumor, i.e., stromal and epithelial, are neoplastic.
  • The authors report preliminary immunohistochemical and electron microscopic studies of the epithelial component from one case of a typical, benign, mixed epithelial, and stromal tumor of the kidney.
  • The authors believe that in a benign tumor such morphologic heterogeneity is inconsistent with neoplastic proliferation.
  • Therefore, they postulate that in mixed epithelial and stromal tumor of the kidney the tubules are entrapped rather than neoplastic.
  • [MeSH-major] Epithelial Cells / pathology. Kidney Neoplasms / pathology. Mixed Tumor, Malignant / pathology. Stromal Cells / pathology
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry. Keratin-7. Keratins / analysis. Microscopy, Electron. Neprilysin / analysis

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  • (PMID = 16036882.001).
  • [ISSN] 0191-3123
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / KRT7 protein, human; 0 / Keratin-7; 68238-35-7 / Keratins; EC 3.4.24.11 / Neprilysin
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20. Tarantino-Hutchison LM, Sorrentino C, Nadas A, Zhu Y, Rubin EM, Tinkle SS, Weston A, Gordon T: Genetic determinants of sensitivity to beryllium in mice. J Immunotoxicol; 2009 Jun;6(2):130-5
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  • The mouse ear swelling test (MEST) was employed to determine if these different alleles would support a hypersensitivity response to beryllium.
  • Mice were first sensitized on the back and subsequently challenged on the ear.
  • In the HLA-DPB1*1701 mice, the strain with the highest risk transgene, the Be/Be group was the only group that displayed significant maximum increased ear thickness of 19.6% +/- 3.0% over the baseline measurement (p < 0.05).
  • In addition, inter-strain differences in response to beryllium in seven inbred strains were investigated through use of the MEST, these included: FVB/N, AKR, Balb/c, C3H/HeJ, C57/BL6, DBA/2, and SJL/J.
  • [MeSH-minor] Alleles. Animals. Beryllium / adverse effects. Genetic Predisposition to Disease. HLA-DP beta-Chains. Humans. Mice. Mice, Inbred Strains. Mice, Transgenic. Polymorphism, Genetic. Risk Factors. Skin Tests. Species Specificity. Th1 Cells / immunology

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  • (PMID = 19589099.001).
  • [ISSN] 1547-6901
  • [Journal-full-title] Journal of immunotoxicology
  • [ISO-abbreviation] J Immunotoxicol
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / ES011473
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / HLA-DP Antigens; 0 / HLA-DP beta-Chains; 0 / HLA-DPB1 antigen; OW5102UV6N / Beryllium
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21. Marques CJ, Costa P, Vaz B, Carvalho F, Fernandes S, Barros A, Sousa M: Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia. Mol Hum Reprod; 2008 Feb;14(2):67-74
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  • Genomic imprinting marks in the male germ line are already established in the adult germinal stem cell population.
  • We studied the methylation patterns of H19 and MEST imprinted genes in sperm of control and oligozoospermic patients, by bisulphite genomic sequencing.
  • We here report that 7 out of 15 (46.7%) patients with a sperm count below 10 x 10(6)/ml display defective methylation of H19 and/or MEST imprinted genes.
  • Conversely, hypermethylation occurred in 8.3% (3.8-12.2%) and complete methylation in 6.1% (3.8-7.6%) of MEST clones.
  • Of the seven patients presenting imprinting errors, two had both H19 hypomethylation and MEST hypermethylation, whereas five displayed only one imprinted gene affected.
  • The frequency of patients with MEST hypermethylation was highest in the severe oligozoospermia group (2/5 patients), whereas H19 hypomethylation was more frequent in the moderate oligozoospermia (2/5 patients).

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  • (PMID = 18178607.001).
  • [ISSN] 1460-2407
  • [Journal-full-title] Molecular human reproduction
  • [ISO-abbreviation] Mol. Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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22. Colombo P, Naspro R, Vallieri L, Vavassori I, Valenti S, Galli C, Roncalli M: Non-hormone-induced mixed epithelial and stromal tumor of kidney in a man: description of a rare case. Urology; 2008 Jan;71(1):168.e7-9
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  • [Title] Non-hormone-induced mixed epithelial and stromal tumor of kidney in a man: description of a rare case.
  • Mixed epithelial and stromal tumor of the kidney is a recently recognized category of lesions occurring mostly in adult, middle-age women with a history of hormonal treatment.
  • We present a rare case of a 58-year-old asymptomatic man without a history of hormonal treatment with a tumor characterized by proliferation of multiple cysts lined by single layers of epithelial cells and hypercellular stroma of spindle "ovarian-like" cells.
  • Immunohistochemically, the stromal cells reacted against estrogen and progesterone receptors, vimentin, desmin, and CD34.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Neoplasms, Glandular and Epithelial / diagnosis. Stromal Cells / pathology

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  • (PMID = 18242391.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Desmin
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23. Andrade AC, Lui JC, Nilsson O: Temporal and spatial expression of a growth-regulated network of imprinted genes in growth plate. Pediatr Nephrol; 2010 Apr;25(4):617-23
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  • [Title] Temporal and spatial expression of a growth-regulated network of imprinted genes in growth plate.
  • Similar to the coordinated decline previously observed in kidney, lung, liver, and heart, expression of all genes, except Gtl2, decreased with age in metaphyseal bone.
  • On the contrary, Mest, Dlk1, H19, and Gtl2 decreased, and Cdkn1c, Grb10, and Slc38a4 increased with age in growth plate.
  • During differentiation from resting to hypertrophic zone, Mest, Dlk1, Grb10, and Gtl2 expression decreased, whereas Slc38a4 expression increased.
  • In particular, developmental changes in the expression of growth-promoting genes, Mest, Dlk1, Gtl2, and growth-inhibitory genes, Cdkn1c and Grb10, may contribute to the decline in longitudinal bone growth that occurs with age.

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  • [Cites] Endocrinology. 2002 May;143(5):1851-7 [11956168.001]
  • [Cites] Endocrinology. 1994 Sep;135(3):1113-8 [8070354.001]
  • [Cites] Nat Genet. 1995 Oct;11(2):204-6 [7550351.001]
  • [Cites] Genes Dev. 1995 Mar 15;9(6):639-49 [7729683.001]
  • [Cites] J Theor Biol. 1979 Jun 7;78(3):365-74 [513788.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8292-7 [12829789.001]
  • [Cites] Development. 1991 Dec;113(4):1105-14 [1811930.001]
  • [Cites] J Physiol. 1989 Jul;414:55-71 [2607442.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R189-96 [18448610.001]
  • [Cites] J Biol Chem. 1998 Jan 9;273(2):720-8 [9422723.001]
  • [Cites] Hum Mol Genet. 2000 Dec 12;9(20):3101-10 [11115855.001]
  • [Cites] Nature. 1995 May 4;375(6526):34-9 [7536897.001]
  • [Cites] Endocrinology. 2009 Apr;150(4):1791-800 [19036884.001]
  • [Cites] J Endocrinol. 2007 Apr;193(1):75-84 [17400805.001]
  • [Cites] Dev Cell. 2006 Nov;11(5):711-22 [17084362.001]
  • [Cites] Cytogenet Genome Res. 2006;113(1-4):279-91 [16575191.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Apr 15;329(3):909-16 [15752742.001]
  • [Cites] Genes Dev. 1995 Mar 15;9(6):650-62 [7729684.001]
  • [Cites] Nat Med. 1999 Jun;5(6):623-8 [10371499.001]
  • [Cites] Nat Genet. 1999 Oct;23(2):199-202 [10508517.001]
  • [Cites] J Endocrinol. 2006 Apr;189(1):27-36 [16614378.001]
  • [Cites] Anal Biochem. 2001 Aug 1;295(1):17-21 [11476540.001]
  • [Cites] Cytogenet Genome Res. 2006;113(1-4):188-93 [16575179.001]
  • [Cites] Anticancer Res. 2002 Nov-Dec;22(6C):4173-8 [12553051.001]
  • [Cites] Trends Endocrinol Metab. 2004 Oct;15(8):370-4 [15380808.001]
  • [Cites] Endocrinology. 2008 Apr;149(4):1820-8 [18174286.001]
  • [Cites] J Endocrinol. 2007 Jul;194(1):31-40 [17592018.001]
  • [Cites] Bone. 2007 Mar;40(3):577-86 [17169623.001]
  • (PMID = 19902269.001).
  • [ISSN] 1432-198X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Proteins; 0 / RNA, Messenger
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24. Modigh K: [The most vulnerable addicts deserted by the National Board of Health and Welfare]. Lakartidningen; 2007 May 2-8;104(18):1426-7; discussion 1427
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  • [Transliterated title] Socialstyrelsen sviker de mest utsatta missbrukarna.


25. Hara N, Kawaguchi M, Murayama S, Maruyama R, Tanikawa T, Takahashi K: Mixed epithelial and stromal tumor of the kidney in a 12-year-old girl. Pathol Int; 2005 Oct;55(10):670-6
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  • [Title] Mixed epithelial and stromal tumor of the kidney in a 12-year-old girl.
  • Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare kidney neoplasm that almost exclusively occurs in perimenopausal women, and long-term estrogen replacement is relevant to its pathogenesis.
  • On surgical specimen it was found that the well-circumscribed tumor measuring 14 cm arose from the lower pole of the right kidney, showing solid and fibrous-cystic areas.
  • Microscopically, it was composed both of epithelial structures similar to renal tubules and stroma comprising non-specific spindle cells.
  • In addition, primitive ductal structures were reactive both for CD15 and lectins, but immature epithelial elements typical of nephroblastoma were absent.
  • The tumor was comparable with MESTK, although some epithelia were associated with the immunophenotype of proximal tubules.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Child. Disease-Free Survival. Female. Humans. Immunoenzyme Techniques. Treatment Outcome

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  • (PMID = 16185300.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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26. Yang Y, Nie X, Lu J, Lu XY, Wei YY, Wang H, Han ZH, Chen ZH, Zheng J: [Mixed epithelial and stromal tumor of kidney]. Zhonghua Bing Li Xue Za Zhi; 2006 Jan;35(1):29-31
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  • [Title] [Mixed epithelial and stromal tumor of kidney].
  • OBJECTIVE: To study the clinicopathological features and differential diagnoses of mixed epithelial and stromal tumor of the kidney.
  • METHODS: Clinical and pathological characteristics of 4 cases of mixed epithelial and stromal tumor of the kidney were studied.
  • Radiologic studies revealed cystic and solid masses involving the kidney.
  • Microscopically, the tumors were composed of a mixture of stromal and epithelial elements.
  • The epithelial elements were variable in cell types including cuboidal, hobnail and columnar cells.
  • One case showed Müllerian and intestinal epithelial differentiations.
  • Stromal elements essentially consisted of spindle cells, with thick-walled blood vessels and bands of smooth muscle cells as distinctive features of the tumor.
  • Immunohistochemical staining revealed that the epithelial components were positive for AE1/AE3, whereas the stromal components were positive for ER, PR, and SMA.
  • CONCLUSIONS: Mixed epithelial and stromal tumor of the kidney is a benign neoplasm with distinct histopathological features.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Muscle, Smooth / metabolism. Nephrectomy / methods. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16608646.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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27. Jäger S, Schönherr N, Spengler S, Ranke MB, Wollmann HA, Binder G, Eggermann T: LOT1 (ZAC1/PLAGL1) as member of an imprinted gene network does not harbor Silver-Russell specific variants. J Pediatr Endocrinol Metab; 2009 Jun;22(6):555-9
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  • These chromosomes harbor the imprinted genes IGF2, H19, LIT1 and MEST.
  • Interestingly, two of these variants, g.10212T/A and g.10214C/A, showed strict association.
  • [MeSH-major] Cell Cycle Proteins / genetics. Craniofacial Abnormalities / genetics. Fetal Growth Retardation / genetics. Transcription Factors / genetics. Tumor Suppressor Proteins / genetics

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  • (PMID = 19694203.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / PLAGL1 protein, human; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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28. Xiang H, Ding W, Liu F, Ren GP, Wang ZM, Zhu XZ: [Clinicopathologic analysis of mixed epithelial and stromal tumor of kidney and adult cystic nephroma]. Zhonghua Bing Li Xue Za Zhi; 2009 Jul;38(7):436-40
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  • [Title] [Clinicopathologic analysis of mixed epithelial and stromal tumor of kidney and adult cystic nephroma].
  • OBJECTIVE: To study the clinicopathologic features, immunophenotype and differential diagnosis of mixed epithelial and stromal tumor of kidney (MEST) and adult cystic nephroma (CN).
  • METHODS: Five cases of MEST and 4 cases of CN were retrospectively analyzed.
  • RESULTS: All of the five patients with MEST were females.
  • On gross examination, MEST was well-circumscribed but non-encapsulated.
  • One was composed of a mixture of solid and cystic elements, while the remaining case showed a multicystic cut surface bridged by thick fibrous septa.
  • Histologically, MEST consisted of proliferation of cystically dilated glands admixed with spindly stromal cells with various cellularity and growth patterns.
  • Both the glandular and stromal elements were well-differentiated with no cytologic atypia identified.
  • In contrast, the thin-walled cystic spaces in CN were lined by a single layer of epithelium.Immunohistochemical study showed that the epithelial cells were positive for pan-cytokeratin and epithelial membrane antigen.
  • The spindle cells in MEST expressed vimentin (5/5), smooth muscle actin (3/5), desmin (4/5), CD10 (5/5), estrogen receptor (4/5) and progesterone receptor (4/5).
  • CONCLUSIONS: Both MEST and CN are uncommon renal neoplasm.
  • Most of them run a benign clinical course.
  • The stromal cells in MEST show smooth muscle or myofibroblastic differentiation.
  • MEST and CN share overlapping histological and immunohistochemical features, and may represent spectrum of the same group of lesions.
  • [MeSH-major] Epithelial Cells / pathology. Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Cystic, Mucinous, and Serous / pathology. Stromal Cells / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Carcinoma, Renal Cell / pathology. Desmin / metabolism. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nephroma, Mesoblastic / pathology. Receptors, Estrogen / metabolism. Retrospective Studies. Vimentin / metabolism

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  • (PMID = 19781188.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Desmin; 0 / Receptors, Estrogen; 0 / Vimentin
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29. Torres Gómez FJ, Silva Abad A, Galán P: [Adult's mesoblastic nephroma. Report of a case with aggressive course]. Arch Esp Urol; 2007 Jan-Feb;60(1):72-5
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  • [Title] [Adult's mesoblastic nephroma. Report of a case with aggressive course].
  • [Transliterated title] Nefroma mesoblástico del adulto. Presentación de un caso con curso agresivo.
  • OBJECTIVE: Mesoblastic nephroma is a rare renal neoplasia mainly diagnosed in the first three months of life; there is an adult type with pathologic similarities but it has its own features.
  • METHODS: We report the case of a 71-year-old female patient with the diagnosis of adult mesoblastic nephroma, the clinical outcome of which was ominous.
  • RESULTS: The presence of epithelial elements with tubular conformation surrounded by a spindle cell component is greatly useful to perform the differential diagnosis between this entity and others of greater clinical significance.
  • [MeSH-major] Kidney Neoplasms / pathology. Nephroma, Mesoblastic / pathology

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  • (PMID = 17408177.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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30. Poole RL, Baple E, Crolla JA, Temple IK, Mackay DJ: Investigation of 90 patients referred for molecular cytogenetic analysis using aCGH uncovers previously unsuspected anomalies of imprinting. Am J Med Genet A; 2010 Aug;152A(8):1990-3
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  • Methylation analysis was performed at 13 imprinted loci [PLAGL1, IGF2R, MEST, GRB10, H19, IGF2 DMR2 (IGF2P0), KCNQ1OT1 (KvDMR), MEG3, SNRPN, PEG3, GNAS (GNAS exon 1a and NESP55) and GNASAS].
  • [MeSH-minor] Adolescent. Adult. Child, Preschool. Cohort Studies. Cytogenetic Analysis. Female. Humans. Male

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  • (PMID = 20635366.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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31. Skov RL, Urth TR, Hansen DS: [Methicillin resistant S. aureus and multi-resistant Enterobacteriaceae. Two of the most significant resistance problems in Denmark]. Ugeskr Laeger; 2007 Dec 3;169(49):4259-62
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  • [Transliterated title] Methicillinresistente S. aureus og multiresistente Enterobacteriacea. To af de mest betydningsfulde resistensproblemer i Danmark.

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  • (PMID = 18208704.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Quinolones
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32. Finkielstain GP, Forcinito P, Lui JC, Barnes KM, Marino R, Makaroun S, Nguyen V, Lazarus JE, Nilsson O, Baron J: An extensive genetic program occurring during postnatal growth in multiple tissues. Endocrinology; 2009 Apr;150(4):1791-800
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  • Consistent with this hypothesis, microarray analysis identified more than 1600 genes that were regulated with age (1 vs. 4 wk) coordinately in kidney, lung, and heart of male mice, including many genes that regulate proliferation.
  • As examples, we focused on three growth-promoting genes, Igf2, Mest, and Peg3, that were markedly down-regulated with age.
  • At least some of these are themselves apparently regulated by growth, suggesting that, in the embryo, a gene expression pattern is established that allows for rapid somatic growth of multiple tissues, but then, during postnatal life, this growth leads to negative-feedback changes in gene expression that in turn slow and eventually halt somatic growth, thus imposing a fundamental limit on adult body size.

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  • [Cites] Genesis. 2004 May;39(1):65-72 [15124229.001]
  • [Cites] Pediatr Res. 2008 Sep;64(3):240-5 [18535488.001]
  • [Cites] Trends Endocrinol Metab. 2004 Oct;15(8):370-4 [15380808.001]
  • [Cites] Dev Biol. 1965 Dec;12(3):451-66 [5884354.001]
  • [Cites] Am Rev Respir Dis. 1975 Jun;111(6):803-44 [1094872.001]
  • [Cites] Acta Endocrinol (Copenh). 1978 Dec;89(4):780-8 [716781.001]
  • [Cites] Biol Reprod. 1978 Nov;19(4):807-16 [570431.001]
  • [Cites] Life Sci. 1984 Apr 9;34(15):1487-96 [6708742.001]
  • [Cites] Nature. 1985 Sep 19-25;317(6034):260-2 [2995818.001]
  • [Cites] Biol Reprod. 1986 Mar;34(2):322-6 [3955146.001]
  • [Cites] J Biol Chem. 1986 Oct 5;261(28):13144-50 [3759952.001]
  • [Cites] Development. 1988 Jul;103(3):497-506 [3246220.001]
  • [Cites] J Pharm Pharmacol. 1989 Jul;41(7):439-44 [2570847.001]
  • [Cites] Nature. 1990 May 3;345(6270):78-80 [2330056.001]
  • [Cites] Cell. 1991 Feb 22;64(4):849-59 [1997210.001]
  • [Cites] Endocrinology. 1991 Dec;129(6):3281-8 [1659527.001]
  • [Cites] Nucleic Acids Res. 1993 Apr 25;21(8):2009 [8493110.001]
  • [Cites] Nature. 1996 Apr 25;380(6576):711-4 [8614465.001]
  • [Cites] Eur J Pediatr. 1996 May;155(5):362-7 [8741031.001]
  • [Cites] Am J Physiol. 1996 Aug;271(2 Pt 1):L332-9 [8770073.001]
  • [Cites] Physiol Rev. 1996 Oct;76(4):1005-26 [8874492.001]
  • [Cites] J Mol Cell Cardiol. 1996 Aug;28(8):1737-46 [8877783.001]
  • [Cites] Am J Physiol. 1996 Nov;271(5 Pt 2):H2183-9 [8945939.001]
  • [Cites] Endocr Rev. 1997 Oct;18(5):646-61 [9331546.001]
  • [Cites] Nature. 1997 Oct 23;389(6653):809-15 [9349812.001]
  • [Cites] Hum Mol Genet. 1997 Oct;6(11):1907-15 [9302270.001]
  • [Cites] Semin Immunol. 1998 Apr;10(2):127-32 [9618758.001]
  • [Cites] Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):180-91 [10925158.001]
  • [Cites] Dev Biol. 2001 Jan 1;229(1):141-62 [11133160.001]
  • [Cites] J Bone Miner Res. 2000 Dec;15(12):2402-12 [11127205.001]
  • [Cites] Toxicol Sci. 2001 Apr;60(2):285-95 [11248141.001]
  • [Cites] Nat Rev Mol Cell Biol. 2001 Jan;2(1):48-54 [11413465.001]
  • [Cites] J Histochem Cytochem. 2002 Apr;50(4):541-8 [11897807.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4397-402 [11917104.001]
  • [Cites] Am J Physiol Renal Physiol. 2002 May;282(5):F953-65 [11934706.001]
  • [Cites] J Biol Chem. 2002 Jun 21;277(25):23000-7 [11943780.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Sep;83(9):3252-7 [9745438.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Circ Res. 1998 Nov 16;83(10):986-94 [9815146.001]
  • [Cites] Science. 1999 Apr 9;284(5412):330-3 [10195900.001]
  • [Cites] J Pediatr Orthop. 1999 May-Jun;19(3):398-403 [10344328.001]
  • [Cites] Endocrinology. 1999 Jul;140(7):3391-4 [10385438.001]
  • [Cites] Nephron Exp Nephrol. 2004;98(4):e109-13 [15627793.001]
  • [Cites] Endocrinology. 2005 Mar;146(3):1012-7 [15604211.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2814-9 [15710898.001]
  • [Cites] J Mol Endocrinol. 2005 Apr;34(2):489-503 [15821112.001]
  • [Cites] Horm Res. 2005;63(3):125-8 [15795509.001]
  • [Cites] J Biol Chem. 2005 May 6;280(18):18517-24 [15753088.001]
  • [Cites] J Endocrinol. 2005 Jul;186(1):241-9 [16002553.001]
  • [Cites] FASEB J. 2005 Aug;19(10):1302-4 [15928196.001]
  • [Cites] Transpl Immunol. 2005 Oct;15(1):1-8 [16223667.001]
  • [Cites] Nat Rev Neurosci. 2005 Dec;6(12):945-54 [16340955.001]
  • [Cites] Nephron Physiol. 2006;102(3-4):p81-91 [16340241.001]
  • [Cites] Endocrinology. 2006 Nov;147(11):5132-8 [16873534.001]
  • [Cites] Dev Cell. 2006 Nov;11(5):711-22 [17084362.001]
  • [Cites] Pituitary. 2007;10(2):151-7 [17429593.001]
  • [Cites] J Endocrinol. 2007 Jul;194(1):31-40 [17592018.001]
  • [Cites] Endocrinology. 2008 Apr;149(4):1820-8 [18174286.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R189-96 [18448610.001]
  • [Cites] Birth Defects Res B Dev Reprod Toxicol. 2004 Jun;71(3):185-90 [15282739.001]
  • (PMID = 19036884.001).
  • [ISSN] 1945-7170
  • [Journal-full-title] Endocrinology
  • [ISO-abbreviation] Endocrinology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / IGF2 protein, mouse; 0 / Igf2bp3 protein, mouse; 0 / Kruppel-Like Transcription Factors; 0 / Peg3 protein, mouse; 0 / Proteins; 0 / RNA, Messenger; 0 / RNA-Binding Proteins; 0 / mesoderm specific transcript protein; 67763-97-7 / Insulin-Like Growth Factor II
  • [Other-IDs] NLM/ PMC2659288
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33. Dekel B, Metsuyanim S, Schmidt-Ott KM, Fridman E, Jacob-Hirsch J, Simon A, Pinthus J, Mor Y, Barasch J, Amariglio N, Reisner Y, Kaminski N, Rechavi G: Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. Cancer Res; 2006 Jun 15;66(12):6040-9
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  • [Title] Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney.
  • Wilms' tumor (WT), the embryonic kidney malignancy, is suggested to evolve from a progenitor cell population of uninduced metanephric blastema, which typically gives rise to nephrons.
  • However, apart from blastema, WT specimens frequently contain cells that have differentiated into renal tubular or stromal phenotypes, complicating their analysis.
  • We aimed to define tumor-progenitor genes that function in normal kidney development using WT xenografts (WISH-WT), in which the blastema accumulates with serial passages at the expense of differentiated cells.
  • Herein, we did transcriptional profiling using oligonucleotide microarrays of WISH-WT, WT source, human fetal and adult kidneys, and primary and metastatic renal cell carcinoma.
  • Among the most significantly up-regulated genes in WISH-WT, we identified a surprising number of paternally expressed genes (PEG1/MEST, PEG3, PEG5/NNAT, PEG10, IGF2, and DLK1), as well as Meis homeobox genes [myeloid ecotropic viral integration site 1 homologue 1 (MEIS1) and MEIS2], which suppress cell differentiation and maintain self-renewal.
  • Concomitantly, they were significantly induced in human fetal kidneys, strictly developmentally regulated throughout mouse nephrogenesis and overexpressed in the normal rat metanephric blastema.
  • Interestingly, ischemic/reperfusion injury to adult mouse kidneys reinduced the expression of PEG3, PEG10, DLK1, and MEIS1, hence simulating embryogenesis.
  • [MeSH-major] Genomic Imprinting. Kidney Neoplasms / genetics. Wilms Tumor / genetics
  • [MeSH-minor] Animals. Gene Expression Profiling. Homeodomain Proteins / biosynthesis. Homeodomain Proteins / genetics. Humans. Kidney / embryology. Kidney / growth & development. Mice. Mice, Inbred BALB C. Mice, Nude. Mice, SCID. Multigene Family. Neoplasm Proteins / biosynthesis. Neoplasm Proteins / genetics. Neoplasm Transplantation. Neoplastic Stem Cells. Oligonucleotide Array Sequence Analysis. Rats. Transplantation, Heterologous

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  • (PMID = 16778176.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Neoplasm Proteins; 0 / myeloid ecotropic viral integration site 1 protein
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34. Rauf F, Yaqoob N, Husain A: Mixed epithelial and stromal tumour of kidney. J Pak Med Assoc; 2006 Jul;56(7):340-1
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  • [Title] Mixed epithelial and stromal tumour of kidney.
  • Mixed epithelial and stromal tumour of kidney is a recently described, rare entity and includes cases previously termed as cystic hamartoma of renal pelvis and adult mesoblastic nephroma.
  • During ultrasound abdomen, a solid right renal mass was incidentally found in upper pole of right kidney.
  • On gross examination it was a 3.5 cm diameter mass which was microscopically composed of both epithelial and stromal components in the form of cystically dilated tubules and fascicles of spindle shaped cells.
  • [MeSH-major] Epithelial Cells / pathology. Kidney Neoplasms / surgery. Kidney Neoplasms / ultrasonography. Stromal Cells / pathology
  • [MeSH-minor] Adult. Female. Humans. Nephrectomy

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  • (PMID = 16900720.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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35. Iqbal J, Gupta S, Breuer FU: Metanephric adenoma mimicking papillary carcinoma arising in a mixed epithelial and stromal tumor of the kidney. Cancer Genet Cytogenet; 2006 Oct 1;170(1):83-5
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  • [Title] Metanephric adenoma mimicking papillary carcinoma arising in a mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Adenoma / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 16965964.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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36. Antic T, Perry KT, Harrison K, Zaytsev P, Pins M, Campbell SC, Picken MM: Mixed epithelial and stromal tumor of the kidney and cystic nephroma share overlapping features: reappraisal of 15 lesions. Arch Pathol Lab Med; 2006 Jan;130(1):80-5
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  • [Title] Mixed epithelial and stromal tumor of the kidney and cystic nephroma share overlapping features: reappraisal of 15 lesions.
  • CONTEXT: Cystic nephroma is a rare cystic tumor, which only recently has been recognized as an exclusively adult lesion.
  • Mixed epithelial and stromal tumor of the kidney is also a rare, recently recognized, biphasic tumor composed of tubular and cystic elements embedded in grossly recognizable spindle cell stroma.
  • OBJECTIVES: To compare clinical phenotype, morphology, and immunohistochemistry in mixed epithelial and stromal tumor of the kidney and cystic nephroma in order to explore the relationship between these 2 lesions.
  • DESIGN: Fifteen biphasic lesions (8 mixed epithelial and stromal tumors of the kidney and 7 cystic nephromas) were studied.
  • RESULTS: Mixed epithelial and stromal tumor of the kidney occurred exclusively in women aged 36 to 80 years (mean, 49.7 years), all of whom had a history of estrogen therapy and/or obesity.
  • Cystic nephroma occurred in both sexes; patients were aged 22 to 71 years (mean, 50.4 years), and a history of hormonal therapy was present on occasion.
  • All 15 lesions were benign.
  • In mixed epithelial and stromal tumors of the kidney, the stroma was positive for estrogen and progesterone receptors in 4 of 5 lesions tested.
  • In cystic nephroma, focal positivity for hormone receptors was seen in 2 of 7 tumors tested; both positive lesions were from women.
  • The epithelial lining in both mixed epithelial and stromal tumor of the kidney and cystic nephroma lesions was variable with regard to shape, cytoplasmic appearance, and immunophenotype (with focal positivity for CD10, cytokeratin 7, high-molecular-weight keratin, and Ulex europaeus detectable in both lesions).
  • CONCLUSIONS: While mixed epithelial and stromal tumor of the kidney has a strong association with the female sex and hormonal milieu, cystic nephroma can affect both sexes and, on occasion, may also have hormonal associations.
  • Our studies also suggest that the tubules may be entrapped rather than comprising an intrinsic component of the tumor.
  • [MeSH-major] Kidney Neoplasms / pathology. Nephroma, Mesoblastic / pathology. Stromal Cells / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasms, Glandular and Epithelial / metabolism. Neoplasms, Glandular and Epithelial / pathology. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16390243.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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37. Tsuchiyama K, Ueki O, Minami H, Kawaguchi K, Sato K, Katsuda S: [Mixed epithelial and stromal tumor of the kidney: a case report]. Hinyokika Kiyo; 2009 Apr;55(4):219-21
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  • [Title] [Mixed epithelial and stromal tumor of the kidney: a case report].
  • We report a case of a mixed epithelial and stromal tumor of the kidney.
  • A 64-year-old female who had no complaint was found to have a left renal tumor by computed tomography (CT) for an examination of a right breast tumor and was referred to our department.
  • CT revealed a gradually enhancing 5 cm mass in the left kidney.
  • The patient underwent left radical nephrectomy, and the tumor was histologically diagnosed as a mixed epithelial and stromal tumor.
  • [MeSH-major] Kidney Neoplasms / pathology
  • [MeSH-minor] Aged. Epithelial Cells / pathology. Female. Humans. Stromal Cells / pathology

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  • (PMID = 19462828.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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38. Chang G, Liu S, Wang F, Zhang Y, Kou Z, Chen D, Gao S: Differential methylation status of imprinted genes in nuclear transfer derived ES (NT-ES) cells. Genomics; 2009 Feb;93(2):112-9
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  • In contrast to H19, maternally imprinted genes, Mest and Peg3, showed relatively stable methylation patterns in ES cells, especially Peg3, which displayed better capability in enduring long-term culture in vitro.

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  • (PMID = 18948186.001).
  • [ISSN] 1089-8646
  • [Journal-full-title] Genomics
  • [ISO-abbreviation] Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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39. Ferraro TN, Smith GG, Schwebel CL, Lohoff FW, Furlong P, Berrettini WH, Buono RJ: Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains. Physiol Genomics; 2007 Nov 14;31(3):458-62
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  • [Title] Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.
  • To confirm the presence and refine the position of the chromosome 5 QTL for maximal electroshock seizure threshold (MEST), reciprocal congenic strains between B6 and D2 mice were created by a DNA marker-assisted backcross breeding strategy and studied with respect to changes in MEST.
  • Comparison of MEST between congenic and control (parental genetic background) mice indicates that genes influencing this trait were captured in all strains.
  • Thus, mice from strains having D2 alleles from chromosome 5 on a B6 genetic background exhibit significantly lower MEST compared with control littermates, whereas congenic mice harboring B6 chromosome 5 alleles on a D2 genetic background exhibit significantly higher MEST compared with control littermates.
  • Combining data from all congenic strains, we conclude that the gene(s) underlying the chromosome 5 QTL for MEST resides in the interval between D5Mit108 (26 cM) and D5Mit278 (61 cM).

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  • (PMID = 17698926.001).
  • [ISSN] 1531-2267
  • [Journal-full-title] Physiological genomics
  • [ISO-abbreviation] Physiol. Genomics
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / NS-40554
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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40. Wenzelberg C, Weis M, Akeson J: [Swedish medical students' thoughts prior to medical degree graduation. Family practice, child and adolescent medicine most popular]. Lakartidningen; 2007 Jan 31-Feb 6;104(5):322-5
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  • [Transliterated title] Svenska medicinstudenters tankar inför läkarexamen. Allmänmedicin och barn- och ungdomsmedicin lockar mest.

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  • (PMID = 17328355.001).
  • [ISSN] 0023-7205
  • [Journal-full-title] Läkartidningen
  • [ISO-abbreviation] Lakartidningen
  • [Language] swe
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
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41. Gasior M, Yankura J, Hartman AL, French A, Rogawski MA: Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. Epilepsia; 2010 Aug;51(8):1385-94
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  • METHODS: Mice were treated with 2-DG or 3-MG and the seizure threshold determined in the 6-Hz test, the mouse electroshock seizure threshold (MEST) test, and the intravenous pentylenetetrazol (i.v.
  • KA) seizure threshold tests.
  • RESULTS: 2-DG (125-500 mg/kg, i.p., 30 min before testing) significantly elevated the seizure threshold in the 6-Hz seizure test.
  • 2-DG (250-500 mg/kg) decreased the threshold in the MEST and i.v.
  • PTZ and i.v. KA tests.
  • 3-MG had no effect on seizure threshold in the 6-Hz test but, like 2-DG, decreased seizure threshold in the i.v. PTZ test.
  • CONCLUSIONS: Although 2-DG protects against seizures in the 6-Hz seizure test, it promotes seizures in some other models.

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  • [Copyright] Wiley Periodicals, Inc. © 2010 International League Against Epilepsy.
  • (PMID = 20491877.001).
  • [ISSN] 1528-1167
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Antimetabolites; 0 / Blood Glucose; 9G2MP84A8W / Deoxyglucose; SIV03811UC / Kainic Acid; TZP1275679 / 3-Hydroxybutyric Acid; WM5Z385K7T / Pentylenetetrazole
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42. Teshome K, Gebre-Mariam T, Asres K, Engidawork E: Toxicity studies on dermal application of plant extract of Dodonaea viscosa used in Ethiopian traditional medicine. Phytother Res; 2010 Jan;24(1):60-9
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  • To this effect, the dermatotoxicity of an 80% methanol extract of the leaf was investigated in animals following standard procedures for irritation, sensitization, acute toxicity and repeated toxicity tests.
  • The skin irritation test in rabbits showed the extract to be a slight or negligibly slight irritant, with a primary irritation index of 0.45.
  • A sensitization test in mice by the mouse ear swelling test method revealed the extract to be a non-sensitizer in the dose range 12-30 mg/mL.
  • The acute and repeated dermal toxicity tests on rats did not show any overt sign of toxicity.
  • [MeSH-minor] Administration, Cutaneous. Animals. Female. Male. Medicine, African Traditional. Mice. Plant Leaves / toxicity. Plants, Medicinal / toxicity. Rabbits. Rats. Toxicity Tests

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  • [Copyright] (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19441008.001).
  • [ISSN] 1099-1573
  • [Journal-full-title] Phytotherapy research : PTR
  • [ISO-abbreviation] Phytother Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Plant Extracts
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43. Mai KT, Elkeilani A, Veinot JP: Mixed epithelial and stromal tumour (MEST) of the kidney: report of 14 cases with male and PEComatous variants and proposed histopathogenesis. Pathology; 2007 Apr;39(2):235-40
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  • [Title] Mixed epithelial and stromal tumour (MEST) of the kidney: report of 14 cases with male and PEComatous variants and proposed histopathogenesis.
  • AIMS: This article adds new cases and variants of MEST with discussion of the histopathogenesis.
  • METHODS AND RESULTS: Fourteen MEST were originally diagnosed as cystic nephroma which represents an incidence of 1.6% of renal neoplasms in adults.
  • In females, the stromal component showed areas of müllerian differentiation with positive immunoreactivity for oestrogen (ER) and progesterone receptors (PR) and CD10.
  • The epithelial component displayed features of müllerian epithelium and reactive renal tubular cells.
  • In two male cases, MEST consisted of fibrous and smooth muscle stroma and cysts lined only by reactive renal tubular cells.
  • CONCLUSIONS: MEST represents a tumour developing from müllerian-like stromal cells in the kidney.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology
  • [MeSH-minor] Adult. Aged. Angiomyolipoma / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Kidney Diseases, Cystic / pathology. Male. Middle Aged. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Sex Factors

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  • (PMID = 17454754.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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44. Hiura H, Obata Y, Komiyama J, Shirai M, Kono T: Oocyte growth-dependent progression of maternal imprinting in mice. Genes Cells; 2006 Apr;11(4):353-61
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  • Here, we analyzed the methylation of DMR for each eight imprinted genes (Igf2r, Lit1, Zac1, Snrpn, Peg1/Mest, Impact, Meg1/Grb10, and H19) by bisulfite sequencing methylation assay, using oocytes from 10 dpp (days post partum), 15 dpp, 20 dpp, and adult mice.
  • More than 85% of DMR methylation was achieved for both Igf2r, Zac1 & Lit1 with oocyte size of reaching 55 microm and Snrpn, Peg1/Mest, Impact, and Meg1/Grb10 with oocyte size of reaching 60 microm.
  • Preferential methylation of maternal allele was observed in Zac1 and Peg1/Mest of juvenile oocytes and in Snrpn of juvenile and adult oocytes.
  • The size-dependent-methylation was also recognized in the growing oocytes collected from adult mice, although the progress is slightly slower than that of juvenile mice.
  • [MeSH-minor] Alleles. Animals. Autoantigens / genetics. Cell Cycle / physiology. Cell Cycle Proteins / genetics. DNA / genetics. DNA / metabolism. DNA Methylation. Female. GRB10 Adaptor Protein / genetics. Genes, Tumor Suppressor. Mice. Mice, Inbred C57BL. Mice, Inbred DBA. Proteins / genetics. Ribonucleoproteins, Small Nuclear / genetics. Transcription Factors / genetics. snRNP Core Proteins

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  • (PMID = 16611239.001).
  • [ISSN] 1356-9597
  • [Journal-full-title] Genes to cells : devoted to molecular & cellular mechanisms
  • [ISO-abbreviation] Genes Cells
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Autoantigens; 0 / Cell Cycle Proteins; 0 / Grb10 protein, mouse; 0 / Impact protein, mouse; 0 / Plagl1 protein, mouse; 0 / Proteins; 0 / Ribonucleoproteins, Small Nuclear; 0 / Transcription Factors; 0 / mesoderm specific transcript protein; 0 / snRNP Core Proteins; 151441-47-3 / GRB10 Adaptor Protein; 9007-49-2 / DNA
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45. Spielmann H: The way forward in reproductive/developmental toxicity testing. Altern Lab Anim; 2009 Dec;37(6):641-56
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  • A comparison of the test guidelines for drugs, agrochemicals and industrial chemicals shows that, for historical reasons, significantly different testing strategies are applied.
  • The current status of development and validation of in vitro tests in reproductive toxicology is also critically evaluated.
  • The mouse embryonic stem cell test (mEST) is the most advanced and promising of the in vitro tests.
  • Moreover, promising molecular endpoints have been established in the mEST, including proteomic and toxicogenomic endpoints.
  • In addition, an overview is given on new in vitro reproductive toxicity tests that are currently being developed in the EU FP6 project, ReProTect, since the ReProTect test battery, which covers the essential steps of female and male fertility, implantation and embryotoxicity, holds promise for use as a screening assay for reproductive toxicity testing according to the EU REACH legislation.
  • However, since validated in vitro methods will not be available in the short term, opportunities for the refinement of the standard in vivo tests are discussed, in order to reduce the numbers of animal used in reproductive toxicity testing.
  • Finally, recommendations for toxicity testing in the 21st century call for the harmonisation of test methods across all areas of regulatory testing as a first step.
  • In particular, the implementation of a new 'extended one-generation reproductive toxicity study' (EOGRTS), which includes triggers for additional testing for fertility, developmental neurotoxicity and immunotoxicity, would significantly reduce test animal numbers.
  • It is concluded that in vitro methods hold great promise for reproductive toxicity testing in the 21st century, e.g. the ReProTect in vitro battery and the embryonic stem cell (ESC) technology focusing on molecular endpoints in both the mEST and the hEST.
  • [MeSH-major] Animal Testing Alternatives / methods. Growth and Development / drug effects. Mutagenicity Tests / methods. Reproduction / drug effects. Toxicity Tests / methods

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  • [Copyright] 2009 FRAME.
  • (PMID = 20105000.001).
  • [ISSN] 0261-1929
  • [Journal-full-title] Alternatives to laboratory animals : ATLA
  • [ISO-abbreviation] Altern Lab Anim
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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46. Lee D, Lee Y: The Korea national research resource center. Biopreserv Biobank; 2009 Sep;7(3):137-42
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  • The Korea National Research Resource Center (KNRRC) is supported by the Ministry of Education, Science, and Technology (MEST) and consists of 33 research resource centers (RRCs), 5 core centers, and a head office.

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  • (PMID = 24835879.001).
  • [ISSN] 1947-5535
  • [Journal-full-title] Biopreservation and biobanking
  • [ISO-abbreviation] Biopreserv Biobank
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Hora M, Hes O, Michal M, Boudová L, Chudácek Z, Kreuzberg B, Klecka J: Extensively cystic renal neoplasms in adults (Bosniak classification II or III)--possible "common" histological diagnoses: multilocular cystic renal cell carcinoma, cystic nephroma, and mixed epithelial and stromal tumor of the kidney. Int Urol Nephrol; 2005;37(4):743-50
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  • [Title] Extensively cystic renal neoplasms in adults (Bosniak classification II or III)--possible "common" histological diagnoses: multilocular cystic renal cell carcinoma, cystic nephroma, and mixed epithelial and stromal tumor of the kidney.
  • RESULTS: Seven multilocular cystic renal cell carcinomas, three mixed epithelial and stromal tumour of the kidney and one cystic nephroma were diagnosed on histology.
  • CONCLUSION(S): Extensively cystic renal tumours classified as the Bosniak type II or III correspond histologically to the entities mentioned above (multilocular cystic renal cell carcinoma, cystic nephroma, mixed epithelial and stromal tumour of the kidney).
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male. Middle Aged. Nephrectomy. Retrospective Studies. Wilms Tumor / pathology


48. Zetterström R: [Nils Rosen--one of the world's most important physicians]. Lakartidningen; 2006 Dec 13;103(50-52):4067-9
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  • [Transliterated title] Nils Rosén--en av världens mest betydelsefulla läkare.

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  • (PMID = 17330614.001).
  • [ISSN] 0023-7205
  • [Journal-full-title] Läkartidningen
  • [ISO-abbreviation] Lakartidningen
  • [Language] swe
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits
  • [Publication-country] Sweden
  • [Personal-name-as-subject] Rosen N
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49. Li Y, Meng G, Guo QN: Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma. Exp Mol Pathol; 2008 Jun;84(3):234-9
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  • Genomic imprinting, a heritable form of epigenetic information, is thought to play an important role in tumor progression.
  • Ten imprinted genes, including H19, MKRN3, NDN, CDKN1C, PHLDA2, MEST, CD81, GRB10, SLC22A18, and SLC22A3 were aberrantly regulated in transformed cells, suggesting roles in tumorigenesis.


50. Luszczki JJ, Czuczwar SJ: Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy. Prog Neuropsychopharmacol Biol Psychiatry; 2007 Mar 30;31(2):529-38
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  • To characterize the type of interactions between vigabatrin (VGB) and tiagabine (TGB) -- two newer antiepileptic drugs influencing GABA-ergic neurotransmitter system, the isobolographic analysis was used in two experimental models of epilepsy: the maximal electroshock seizure threshold (MEST) test and pentylenetetrazole (PTZ)-induced seizures in mice.
  • Results indicated that VGB and TGB administered separately (i.p.) increased the electroconvulsive threshold in mice, which allowed the calculation of their TID(20) values (threshold increasing doses by 20% over the threshold of control animals) in the MEST test.
  • With isobolography, the combinations of VGB with TGB (at fixed-ratios of 1:3, 1:1 and 3:1) exerted additive interactions in the MEST test in mice.
  • Only the combination of VGB with TGB at the fixed-ratio of 3:1 was additive in the PTZ test.
  • The evaluation of acute adverse-effect potential for all fixed-ratio combinations of VGB with TGB (administered at their TID(20) and ED(50) values from the MEST and PTZ tests) revealed that none of the examined combinations affected motor coordination in the chimney test and altered neuromuscular tone in the grip-strength test in mice.
  • In contrast, VGB in combinations with TGB produced the antinociceptive effects with respect to suppression of acute thermal pain in animals subjected to the hot-plate test.

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  • (PMID = 17204358.001).
  • [ISSN] 0278-5846
  • [Journal-full-title] Progress in neuro-psychopharmacology & biological psychiatry
  • [ISO-abbreviation] Prog. Neuropsychopharmacol. Biol. Psychiatry
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Nipecotic Acids; GR120KRT6K / Vigabatrin; WM5Z385K7T / Pentylenetetrazole; Z80I64HMNP / tiagabine
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51. Tveden-Nyborg PY, Alexopoulos NI, Cooney MA, French AJ, Tecirlioglu RT, Holland MK, Thomsen PD, D'Cruz NT: Analysis of the expression of putatively imprinted genes in bovine peri-implantation embryos. Theriogenology; 2008 Oct 15;70(7):1119-28
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  • This study reports original data on the expression pattern of 8 putatively imprinted genes (Ata3, Dlk1, Gnas, Grb10, Magel2, Mest-1, Ndn and Sgce) in bovine peri-implantation embryos.
  • Among the 8 genes investigated, only Mest-1 showed differential expression in Day 21 parthenogenetic embryos compared to in vivo and IVP counterparts, indicating maternal imprinting of this gene.

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  • (PMID = 18675451.001).
  • [ISSN] 0093-691X
  • [Journal-full-title] Theriogenology
  • [ISO-abbreviation] Theriogenology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Jevremovic D, Lager DJ, Lewin M: Cystic nephroma (multilocular cyst) and mixed epithelial and stromal tumor of the kidney: a spectrum of the same entity? Ann Diagn Pathol; 2006 Apr;10(2):77-82
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  • [Title] Cystic nephroma (multilocular cyst) and mixed epithelial and stromal tumor of the kidney: a spectrum of the same entity?
  • The recently described mixed epithelial and stromal tumor (MEST) of the kidney and adult cystic nephroma (CN) (multilocular cyst) are rare benign cystic renal neoplasms that are composed of epithelial and stromal elements.
  • Our objective in this study was to evaluate cases of CN and MEST to define the morphological, immunophenotypic, and clinical features of these two entities.
  • Eleven cases from the files of a single institution diagnosed from 1996 to the present as either CN or MEST were reviewed.
  • Architecturally, all lesions were composed of multiple noncommunicating cysts lined by a single layer of epithelial cells.
  • All cases had areas with increased stromal cellularity and 8 cases had ovarian-like stroma present at least focally within the tumor.
  • No stromal or epithelial cell atypia, blastemal elements, or increased mitotic activity was appreciated.
  • The immunoprofile was also similar in the 7 cases stained and included epithelial reactivity with keratin and CAM 5.2 and stromal reactivity with estrogen receptor, progesterone receptor, smooth muscle actin, WT-1, vimentin, and focal desmin.
  • All cases have acted in a benign fashion with no history of recurrence or metastasis.
  • We propose that CN and MEST of the kidney represent a spectrum of the same entity.
  • If the diagnosis of CN is limited to cases that are comprised entirely of thin fibrous-walled cysts, all 11 of our cases would be classified as MEST.
  • [MeSH-major] Kidney Diseases, Cystic / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Complex and Mixed / diagnosis
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasms, Glandular and Epithelial / metabolism. Neoplasms, Glandular and Epithelial / pathology. Stromal Cells

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  • (PMID = 16546041.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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53. Martinez R, Martin-Subero JI, Rohde V, Kirsch M, Alaminos M, Fernandez AF, Ropero S, Schackert G, Esteller M: A microarray-based DNA methylation study of glioblastoma multiforme. Epigenetics; 2009 May 16;4(4):255-64
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  • Glioblastoma multiforme (GBM) is the most frequent and devastating primary brain tumor in adults.
  • The presence of epigenetic lesions, like hypermethylation of known tumor suppressor genes such as MGMT, has been widely described in GBM, but to our knowledge, a genome-wide profile of DNA methylation changes in these lethal tumors is not yet available.
  • The most frequently hypermethylated genes were HOXA11, CD81, PRKCDBP, TES, MEST, TNFRSF10A and FZD9, being involved in more than half of the cases.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Line, Tumor. Cluster Analysis. CpG Islands. Epigenesis, Genetic. Female. Gene Expression Profiling. Humans. Male. Middle Aged. Oligonucleotide Array Sequence Analysis. Polycomb-Group Proteins. Repressor Proteins / metabolism

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  • (PMID = 19550145.001).
  • [ISSN] 1559-2308
  • [Journal-full-title] Epigenetics
  • [ISO-abbreviation] Epigenetics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Polycomb-Group Proteins; 0 / Repressor Proteins
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54. Moon YS, Park SK, Kim HT, Lee TS, Kim JH, Choi YS: Imprinting and expression status of isoforms 1 and 2 of PEG1/MEST gene in uterine leiomyoma. Gynecol Obstet Invest; 2010;70(2):120-5
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  • [Title] Imprinting and expression status of isoforms 1 and 2 of PEG1/MEST gene in uterine leiomyoma.
  • PEG1/MEST gene has been known to be an imprinting gene, which is associated with growth of mesodermal origin cells.
  • The purpose of this study was to investigate whether overexpression of PEG1/MEST gene in leiomyoma is associated with loss of imprinting of the gene (biallelic), or whether the overexpression occurs while maintaining the imprinting (monoallelic).
  • We investigated the expression and the imprinting status of PEG1/MEST and its isoforms in samples from 25 patients with uterine leiomyomas as well as in matched normal myometrial tissue.
  • All normal myometrial tissues and 19 of 20 leiomyomas showed monoallelic expression of PEG1/MEST.
  • Thus, these data demonstrated that tumorigenesis of leiomyoma is associated with overexpression of isoform 1 of PEG1/MEST gene, but not with loss of imprinting of the gene.

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20339302.001).
  • [ISSN] 1423-002X
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Protein Isoforms; 0 / Proteins; 0 / RNA, Messenger; 0 / mesoderm specific transcript protein
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55. National Toxicology Program: Toxicology studies of pentaerythritol triacrylate (technical grade) (CAS No. 3524-68-3) in F344/N rats, B6C3F1 mice, and genetically modified (FVB Tg.AC hemizygous) mice (dermal studies). Natl Toxicol Program Genet Modif Model Rep; 2005 Oct;(4):1-190
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  • Pentaerythritol triacrylate was nominated by the National Cancer Institute for testing based on its high production volume and use, its potential for human exposure, and a lack of adequate testing of the chemical.
  • Genetic toxicology was evaluated in Salmonella typhimurium and in B6C3F(1) and Tg.AC hemizygous mouse peripheral blood erythrocytes.
  • One female vehicle control mouse was sacrificed during the first week of the study due to ataxia and one 1.5 mg/kg female died during week 8.
  • In an irritancy study in which formulations of pentaerythritol triacrylate (approximately 10% or 45% pure) in acetone were applied to the ear, the maximal nonirritating concentration was 0.1% and the minimal irritating concentration was 0.25% for both mixtures.
  • A mouse ear swelling test yielded negative results for pentaerythritol triacrylate as a potential contact sensitizer using the 10% mixture and positive results with the 45% mixture.

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  • (PMID = 18784764.001).
  • [ISSN] 1556-5246
  • [Journal-full-title] National Toxicology Program genetically modified model report
  • [ISO-abbreviation] Natl Toxicol Program Genet Modif Model Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acrylates; 0 / Carcinogens; 0 / Propylene Glycols; PJJ1161ULF / pentaerythrityl triacrylate
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56. Sansom SN, Hébert JM, Thammongkol U, Smith J, Nisbet G, Surani MA, McConnell SK, Livesey FJ: Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap. Development; 2005 Sep;132(17):3947-61
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  • [Title] Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap.
  • One such gene, Mest, was predicted by those studies to be a direct target of Fgf8 signalling and to be involved in setting up, rather than implementing, the progenitor cell protomap.
  • In support of this, we confirmed Mest as a direct transcriptional target of Fgf8-regulated signalling in vitro.

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  • [Cites] J Neurosci. 2000 May 15;20(10):3714-24 [10804213.001]
  • [Cites] Trends Neurosci. 1989 Oct;12(10):400-6 [2479138.001]
  • [Cites] Curr Opin Neurobiol. 2003 Feb;13(1):57-69 [12593983.001]
  • [Cites] Development. 2004 Nov;131(22):5639-47 [15509764.001]
  • [Cites] Nucleic Acids Res. 1999 Mar 15;27(6):1558-60 [10037822.001]
  • [Cites] Genome Biol. 2001;2(10):RESEARCH0042 [11597334.001]
  • [Cites] J Neurosci. 1998 Aug 1;18(15):5723-45 [9671663.001]
  • [Cites] J Neurosci. 1997 Feb 15;17 (4):1425-34 [9006984.001]
  • [Cites] Science. 1999 Aug 6;285(5429):906-9 [10436162.001]
  • [Cites] Cereb Cortex. 1999 Sep;9(6):601-10 [10498278.001]
  • [Cites] Science. 2000 Apr 14;288(5464):344-9 [10764649.001]
  • [Cites] Dev Dyn. 2003 Mar;226(3):460-9 [12619132.001]
  • [Cites] J Neurosci. 1996 Oct 1;16(19):6183-96 [8815900.001]
  • [Cites] J Neurosci. 1999 Dec 15;19(24):10877-85 [10594069.001]
  • [Cites] Curr Biol. 2000 Mar 23;10(6):301-10 [10744971.001]
  • [Cites] Pigment Cell Res. 2002 Aug;15(4):305-9 [12100497.001]
  • [Cites] J Neurosci. 2002 Sep 1;22(17 ):7627-38 [12196586.001]
  • [Cites] Bioinformatics. 2004 Mar 1;20(4):578-80 [14990455.001]
  • [Cites] Neuron. 2002 Sep 12;35(6):1029-41 [12354394.001]
  • [Cites] Development. 1995 Feb;121(2):439-51 [7768185.001]
  • [Cites] Nature. 1990 Aug 2;346(6283):418 [2142998.001]
  • [Cites] Cereb Cortex. 1999 Sep;9(6):586-600 [10498277.001]
  • [Cites] Development. 1992 Aug;115(4):1111-9 [1280558.001]
  • [Cites] J Neurosci. 1998 Feb 15;18(4):1408-18 [9454850.001]
  • [Cites] J Neurosci. 1999 Jul 15;19(14):5967-79 [10407035.001]
  • [Cites] Nat Rev Genet. 2000 Oct;1(1):20-9 [11262869.001]
  • [Cites] Dev Suppl. 1991;Suppl 2:105-22 [1842349.001]
  • [Cites] Development. 1999 Oct;126(20):4465-75 [10498682.001]
  • [Cites] Cell. 1994 Feb 25;76(4):761-75 [8124714.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10729-34 [10485894.001]
  • [Cites] J Neurosci. 2000 Oct 15;20(20):7682-90 [11027229.001]
  • [Cites] Brain Res Dev Brain Res. 2001 May 31;128(1):83-90 [11356266.001]
  • [Cites] Neuron. 2004 Aug 5;43(3):359-72 [15294144.001]
  • [Cites] Cell. 2003 Apr 18;113(2):235-48 [12705871.001]
  • [Cites] Nat Neurosci. 2000 Jul;3(7):679-86 [10862700.001]
  • [Cites] Nat Neurosci. 2003 Aug;6(8):825-31 [12872126.001]
  • [Cites] Cell. 1993 Dec 31;75(7):1417-30 [7916661.001]
  • [Cites] Genes Dev. 2001 Aug 15;15(16):2054-9 [11511537.001]
  • [Cites] Science. 2000 Jan 7;287(5450):134-7 [10615048.001]
  • [Cites] Development. 1997 Jun;124(11):2203-12 [9187146.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1374-9 [14734810.001]
  • [Cites] Curr Biol. 2001 Jan 9;11(1):39-43 [11166178.001]
  • [Cites] J Exp Zool. 1998 Dec 15;282(6):677-90 [9846380.001]
  • [Cites] Genesis. 2003 Apr;35(4):214-9 [12717732.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):11038-43 [11005875.001]
  • [Cites] Genes Cells. 1999 May;4(5):267-76 [10421837.001]
  • [Cites] Gene Expr Patterns. 2003 Aug;3(4):397-405 [12915301.001]
  • [Cites] Development. 2003 May;130(9):1903-14 [12642494.001]
  • [Cites] J Neurosci. 2004 Mar 3;24(9):2247-58 [14999075.001]
  • [Cites] J Neurosci. 2002 Feb 1;22(3):863-75 [11826116.001]
  • [Cites] Curr Opin Neurobiol. 2001 Feb;11(1):50-8 [11179872.001]
  • [Cites] Development. 1997 Sep;124(17):3221-32 [9310317.001]
  • [Cites] Cell. 1993 Dec 31;75(7):1401-16 [8269518.001]
  • [Cites] Cereb Cortex. 2002 Feb;12 (2):129-39 [11739261.001]
  • [Cites] Nature. 1994 Mar 31;368(6470):460-3 [8133892.001]
  • [Cites] Development. 2003 Mar;130(6):1101-11 [12571102.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Mech Dev. 1998 Jul;75(1-2):29-42 [9739103.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1757-62 [12574514.001]
  • [Cites] Mech Dev. 1999 Jun;84(1-2):133-8 [10473127.001]
  • [Cites] Curr Opin Genet Dev. 1994 Aug;4(4):535-42 [7950321.001]
  • [Cites] Science. 2001 Nov 2;294(5544):1071-4 [11567107.001]
  • [Cites] Curr Opin Neurobiol. 2002 Feb;12(1):14-25 [11861160.001]
  • [Cites] J Neurosci. 1999 Dec 1;19(23):10357-71 [10575033.001]
  • [Cites] Anal Biochem. 1987 Apr;162(1):156-9 [2440339.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5116-21 [11309499.001]
  • [Cites] Eur J Neurosci. 2003 Apr;17 (7):1375-83 [12713640.001]
  • [Cites] Neuron. 1999 Nov;24(3):541-53 [10595508.001]
  • [Cites] Mech Dev. 2000 May;93(1-2):201-4 [10781957.001]
  • [Cites] Science. 1988 Jul 8;241(4862):170-6 [3291116.001]
  • [Cites] Annu Rev Neurosci. 2003;26:355-80 [14527269.001]
  • [Cites] J Neurosci. 1999 Jun 15;19(12):4889-98 [10366623.001]
  • [Cites] Neuron. 2001 Nov 20;32(4):591-604 [11719201.001]
  • [Cites] Cell. 2000 May 12;101(4):435-45 [10830170.001]
  • [Cites] Dev Dyn. 1997 Jan;208(1):92-106 [8989524.001]
  • [Cites] Dev Biol. 2000 Jun 15;222(2):296-306 [10837119.001]
  • (PMID = 16079153.001).
  • [ISSN] 0950-1991
  • [Journal-full-title] Development (Cambridge, England)
  • [ISO-abbreviation] Development
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 064611; United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proteins; 0 / Transcription Factors; 0 / mesoderm specific transcript protein; 62031-54-3 / Fibroblast Growth Factors
  • [Other-IDs] NLM/ EMS5311; NLM/ PMC4729368
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57. Stean TO, Atkins AR, Heidbreder CA, Quinn LP, Trail BK, Upton N: Postsynaptic 5-HT1B receptors modulate electroshock-induced generalised seizures in rats. Br J Pharmacol; 2005 Mar;144(5):628-35
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  • 2. The aim of the present study was to investigate the role of 5-HT(1A, 1B and 1D) receptors in modulating generalised seizures in the rat maximal electroshock seizure threshold (MEST) test.
  • 3. The mixed 5-HT receptor agonists SKF 99101 (5-20 mg kg(-1) i.p.) and RU 24969 (1-5 mg kg(-1) i.p.
  • 6. In addition, the ability of the 5-HT(1B/1D) receptor antagonist GR 127935 (0.3-3 mg kg(-1) s.c., 60 min pretest) to dose-dependently inhibit SKF 99101-induced elevation of seizure threshold also suggests possible downstream involvement of 5-HT1D receptors in the action of this agonist, although confirmation awaits the identification of a selective 5-HT1D receptor antagonist.

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  • [Cites] Trends Pharmacol Sci. 2001 May;22(5):224-8 [11339972.001]
  • [Cites] Radiat Res. 1957 Jul;7(1):1-12 [13453662.001]
  • [Cites] Am J Physiol. 1978 Aug;235(2):E97-102 [686171.001]
  • [Cites] Brain Res. 1981 Nov 9;224(1):204-8 [7284836.001]
  • [Cites] Fed Proc. 1984 Jul;43(10):2521-4 [6145628.001]
  • [Cites] Brain Res. 1985 Nov 4;346(2):205-30 [4052776.001]
  • [Cites] Eur J Pharmacol. 1986 Sep 23;129(1-2):131-8 [2429847.001]
  • [Cites] J Neurochem. 1986 Dec;47(6):1832-6 [3772379.001]
  • [Cites] Neuropharmacology. 1986 Aug;25(8):877-86 [3022180.001]
  • [Cites] Epilepsy Res. 1987 Jan;1(1):40-5 [3504382.001]
  • [Cites] Epilepsy Res. 1988 May-Jun;2(3):145-81 [3058469.001]
  • [Cites] Indian J Exp Biol. 1989 Feb;27(2):128-30 [2572545.001]
  • [Cites] EMBO J. 1991 Dec;10(13):4017-23 [1836757.001]
  • [Cites] Neurosci Lett. 1993 Sep 3;159(1-2):179-82 [8264964.001]
  • [Cites] Epilepsia. 1994 Jul-Aug;35(4):889-94 [8082639.001]
  • [Cites] Pharmacol Ther. 1994;62(3):385-405 [7972340.001]
  • [Cites] Brain Res. 1995 Sep 18;692(1-2):111-7 [8548293.001]
  • [Cites] Behav Brain Res. 1996;73(1-2):337-53 [8788530.001]
  • [Cites] Brain Res. 1996 May 25;722(1-2):50-8 [8813349.001]
  • [Cites] Brain Res. 1996 Jun 10;724(1):84-8 [8816259.001]
  • [Cites] Brain Res. 1996 Oct 21;737(1-2):331-4 [8930386.001]
  • [Cites] Life Sci. 1996;59(21):1763-71 [8937503.001]
  • [Cites] Brain Res. 1997 Feb 7;747(2):338-42 [9046012.001]
  • [Cites] Eur J Pharmacol. 1997 Jun 11;328(2-3):153-62 [9218697.001]
  • [Cites] Neuropharmacology. 1997 Apr-May;36(4-5):609-20 [9225286.001]
  • [Cites] Psychopharmacology (Berl). 1997 Jul;132(1):35-43 [9272757.001]
  • [Cites] Eur J Pharmacol. 1997 Jul 23;331(2-3):169-74 [9274976.001]
  • [Cites] Br J Pharmacol. 1997 Aug;121(8):1679-86 [9283703.001]
  • [Cites] Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20 [9303567.001]
  • [Cites] J Med Chem. 1998 Apr 9;41(8):1218-35 [9548813.001]
  • [Cites] Br J Pharmacol. 1998 Sep;125(1):202-8 [9776361.001]
  • [Cites] Eur J Pharmacol. 1998 Oct 16;359(1):33-40 [9831290.001]
  • [Cites] Neuropsychopharmacology. 1999 Aug;21(2 Suppl):52S-60S [10432489.001]
  • [Cites] Brain Res. 1976 May 7;107(2):385-99 [944613.001]
  • (PMID = 15678098.001).
  • [ISSN] 0007-1188
  • [Journal-full-title] British journal of pharmacology
  • [ISO-abbreviation] Br. J. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Indoles; 0 / Piperidones; 0 / Receptor, Serotonin, 5-HT1B; 0 / Receptor, Serotonin, 5-HT1D; 0 / SB 22489G; 0 / Serotonin 5-HT1 Receptor Agonists; 0 / Serotonin 5-HT1 Receptor Antagonists; 0 / Serotonin Antagonists; 0 / Serotonin Receptor Agonists; 0 / Spiro Compounds; 112692-38-3 / Receptor, Serotonin, 5-HT1A; 172378-03-9 / SKF 99101H; 74163-68-1 / 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole
  • [Other-IDs] NLM/ PMC1576040
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58. Terao H, Makiyama K, Yanagisawa M, Miyake M, Sano F, Kita K, Murakami T, Nakaigawa N, Ogawa T, Uemura H, Yao M, Kubota Y, Inayama Y, Nagashima Y: [Mixed epithelial and stromal tumor of kidney: a case report]. Hinyokika Kiyo; 2009 Aug;55(8):495-8
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  • [Title] [Mixed epithelial and stromal tumor of kidney: a case report].
  • Mixed epithelial and stromal tumor of kidney (MEST-K) is a rare benign renal tumor that was first described by Michal and Syrucek in 1998.
  • Here, we report an additional case of MEST-K occurring in a 28-year-old woman.
  • The computed tomography revealed hydronephrosis and a cystic tumor in the right kidney, and laparoscopic right nephrectomy was performed.
  • The resected kidney contained a cystic lesion with a grayish-white mural nodule, in the lower portion.
  • Based on these findings, the tumor was diagnosed as MEST-K.
  • MEST-K was newly introduced to the WHO classification of renal tumors, with a pathogenesis related to long-term estrogen exposure, because of ER and PR expression in the stroma.
  • It is important to consider the possibility of this tumor when encountering cases of cystic tumor in middle-aged and older women, and men with a previous history of estrogen administration.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology
  • [MeSH-minor] Adult. Female. Humans

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  • (PMID = 19764536.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 11
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59. Chu PG, Lau SK, Weiss LM, Jiang Z: Intestinal type of mucinous borderline tumor arising from mixed epithelial and stromal tumor of kidney. Virchows Arch; 2009 Oct;455(4):389-94
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  • [Title] Intestinal type of mucinous borderline tumor arising from mixed epithelial and stromal tumor of kidney.
  • We report a mucinous borderline tumor arising from a mixed epithelial and stromal tumor of left kidney (MESTK).
  • The patient had a cytoscopy with a retrograde pyelogram, which indicated a dilated left kidney with a central mass lesion.
  • Cross-sections of left kidney showed a 4.5 x 3.5 x 1.5 cm ill-defined cystic lesion with mucinous and solid areas.
  • In areas, the mucinous epithelium showed complex proliferation with stratification, papillae formation, and nuclear atypia, resembling that of an ovarian mucinous borderline tumor, a colorectal tubular adenoma, or a low-grade appendiceal mucinous carcinoma.
  • Immunohistochemically, the mucinous borderline tumor showed a colorectal phenotype, being strongly positive for CK20, CDX-2, and MUC2.
  • There was no invasive mucinous tumor identified.
  • We believe that this case represents the first reported example of mucinous borderline tumor arising from a MESTK.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Kidney Neoplasms / pathology. Neoplasms, Glandular and Epithelial / pathology

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  • [Cites] J Urol. 2001 Oct;166(4):1381-2 [11547080.001]
  • [Cites] Am J Surg Pathol. 2007 Apr;31(4):489-500 [17414095.001]
  • [Cites] Arch Pathol Lab Med. 2006 Jan;130(1):80-5 [16390243.001]
  • [Cites] Virchows Arch. 2004 Oct;445(4):359-67 [15322873.001]
  • [Cites] Am J Surg Pathol. 2008 Jun;32(6):884-90 [18425046.001]
  • [Cites] Am J Surg Pathol. 2009 Jan;33(1):72-80 [18971776.001]
  • [Cites] Hum Pathol. 2007 Sep;38(9):1432-7 [17707262.001]
  • [Cites] APMIS. 2008 Nov;116(11):1013-5 [19133001.001]
  • [Cites] Hum Pathol. 2008 Mar;39(3):463-8 [18261632.001]
  • [Cites] Histopathology. 2004 Mar;44(3):302-4 [14987239.001]
  • [Cites] Am J Surg Pathol. 1993 Nov;17(11):1169-75 [8214262.001]
  • [Cites] Virchows Arch. 2005 Sep;447(3):669-71 [16025280.001]
  • [Cites] Am J Surg Pathol. 2006 Sep;30(9):1130-9 [16931958.001]
  • [Cites] Virchows Arch. 2001 Nov;439(5):700-2 [11764393.001]
  • [Cites] Int J Gynecol Pathol. 2002 Oct;21(4):391-400 [12352188.001]
  • [Cites] Pathol Res Pract. 1998;194(6):445-8 [9689654.001]
  • [Cites] Am J Surg Pathol. 2000 Jul;24(7):958-70 [10895818.001]
  • (PMID = 19756727.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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60. Takahashi M, Kamei Y, Ezaki O: Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size. Am J Physiol Endocrinol Metab; 2005 Jan;288(1):E117-24
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  • [Title] Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size.
  • We have found that mesoderm-specific transcript (Mest)/paternally expressed gene 1 (Peg1) gene expression was markedly enhanced in white adipose tissue of mice with diet-induced and genetically caused obesity/diabetes but not with streptozotocin-induced diabetes, which does not cause obesity.
  • Administration of pioglitazone, a drug for type II diabetes and activator of peroxisome proliferator-activated receptor (PPAR)gamma, in obese db/db mice reduced the enhanced expression of Mest mRNA in adipose tissue, concomitant with an increase in body weight and a decrease in the size of adipose cells.
  • Ectopic expression of Mest in 3T3-L1 cells caused increased gene expression of adipose markers such as PPARgamma, CCAAT/enhancer binding protein (C/EBP)alpha, and adipocyte fatty acid binding protein (aP)2.
  • In transgenic mice overexpressing Mest in adipose tissue, enhanced expression of the adipose genes was observed.
  • Thus Mest appears to enlarge adipocytes and could be a novel marker of the size of adipocytes.

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  • (PMID = 15353408.001).
  • [ISSN] 0193-1849
  • [Journal-full-title] American journal of physiology. Endocrinology and metabolism
  • [ISO-abbreviation] Am. J. Physiol. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Dietary Fats; 0 / Hypoglycemic Agents; 0 / Proteins; 0 / RNA, Messenger; 0 / Thiazolidinediones; 0 / mesoderm specific transcript protein; X4OV71U42S / pioglitazone
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61. McMinn J, Wei M, Sadovsky Y, Thaker HM, Tycko B: Imprinting of PEG1/MEST isoform 2 in human placenta. Placenta; 2006 Feb-Mar;27(2-3):119-26
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  • [Title] Imprinting of PEG1/MEST isoform 2 in human placenta.
  • MEST) is expressed in human placental trophoblast and endothelium, and data from knockout mice show that this gene regulates placental and fetal growth.
  • Isoform 1 of PEG1 mRNA initiates from exon 1c and produces the long form of the MEST protein.
  • This isoform is imprinted, with expression only from the paternal allele in many human and mouse organs, including placenta.
  • In contrast, PEG1 isoform 2, initiating from exon 1a and producing the short form of MEST protein, is biallelically expressed (non-imprinted) in several non-placental organs.
  • A CpG island overlapping PEG1 exon 1a is unmethylated in various fetal and adult non-placental tissues, but is often substantially methylated in the placenta, with the extent of methylation in a large series approximating a normal distribution.
  • [MeSH-minor] Adult. Alleles. CpG Islands. DNA / analysis. DNA / metabolism. Exons. Female. Genetic Markers / genetics. Genetic Variation. Humans. Protein Isoforms / genetics. RNA, Messenger / analysis. RNA, Messenger / metabolism. Trophoblasts / chemistry. Trophoblasts / metabolism

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  • (PMID = 16338457.001).
  • [ISSN] 0143-4004
  • [Journal-full-title] Placenta
  • [ISO-abbreviation] Placenta
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Genetic Markers; 0 / Protein Isoforms; 0 / Proteins; 0 / RNA, Messenger; 0 / mesoderm specific transcript protein; 9007-49-2 / DNA
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62. Kagami M, Nagai T, Fukami M, Yamazawa K, Ogata T: Silver-Russell syndrome in a girl born after in vitro fertilization: partial hypermethylation at the differentially methylated region of PEG1/MEST. J Assist Reprod Genet; 2007 Apr;24(4):131-6
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  • [Title] Silver-Russell syndrome in a girl born after in vitro fertilization: partial hypermethylation at the differentially methylated region of PEG1/MEST.
  • METHODS: We examined methylation status of 31 cytosines at the CpG dinucleotides in the DMR of PEG1/MEST on 7q32.2 and 23 cytosines at the CpG dinucleotides in the DMR of H19 on 11p15, using leukocyte genomic DNA.
  • RESULTS: Eight of the 31 cytosines in the patient and four of the 31 cytosines in the father were hypermethylated in the PEG1/MEST-DMR.
  • CONCLUSION: The results suggest that hypermethylation of paternally expressed genes including PEG1/MEST, which usually have growth-promoting effects, may be relevant to LBW in subjects conceived by ART.

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  • [Cites] Am J Hum Genet. 2000 Jan;66(1):36-46 [10631135.001]
  • [Cites] Am J Hum Genet. 2006 Apr;78(4):604-14 [16532391.001]
  • [Cites] J Med Genet. 1999 Jun;36(6):457-60 [10874633.001]
  • [Cites] J Med Genet. 2000 Sep;37(9):E19 [10978366.001]
  • [Cites] Am J Hum Genet. 2001 Jan;68(1):247-53 [11112662.001]
  • [Cites] Nat Genet. 2001 Feb;27(2):153-4 [11175780.001]
  • [Cites] J Med Genet. 2001 Dec;38(12):810-9 [11748303.001]
  • [Cites] Am J Med Genet. 2001 Dec 1;104(3):225-31 [11754049.001]
  • [Cites] N Engl J Med. 2002 Mar 7;346(10):725-30 [11882727.001]
  • [Cites] N Engl J Med. 2002 Mar 7;346(10):731-7 [11882728.001]
  • [Cites] Am J Hum Genet. 2002 Jul;71(1):162-4 [12016591.001]
  • [Cites] Am J Hum Genet. 2003 Jan;72(1):156-60 [12439823.001]
  • [Cites] J Med Genet. 2003 Jan;40(1):62-4 [12525545.001]
  • [Cites] Am J Hum Genet. 2003 May;72(5):1338-41 [12772698.001]
  • [Cites] Am J Hum Genet. 2004 Apr;74(4):599-609 [14991528.001]
  • [Cites] Nat Genet. 1997 May;16(1):16-7 [9140389.001]
  • [Cites] Trends Genet. 1997 Nov;13(11):436-43 [9385840.001]
  • [Cites] Am J Med Genet. 1997 Dec 19;73(3):308-13 [9415690.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):163-9 [9771709.001]
  • [Cites] Nat Genet. 2005 Sep;37(9):1003-7 [16086014.001]
  • [Cites] Hum Mol Genet. 2000 Jul 1;9(11):1587-95 [10861285.001]
  • (PMID = 17450433.001).
  • [ISSN] 1058-0468
  • [Journal-full-title] Journal of assisted reproduction and genetics
  • [ISO-abbreviation] J. Assist. Reprod. Genet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Proteins; 0 / mesoderm specific transcript protein
  • [Other-IDs] NLM/ PMC3455069
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63. Shannon BA, Cohen RJ, Segal A, Baker EG, Murch AR: Clear cell renal cell carcinoma with smooth muscle stroma. Hum Pathol; 2009 Mar;40(3):425-9
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  • Epithelial differentiation of the malignant clear cell components and smooth muscle differentiation of the benign spindle cell stroma was confirmed by the immunostaining profiles and by electron microscopy.
  • We therefore interpret these tumors as unique low-grade variants of clear cell renal cell carcinoma that have induced a prolific metaplastic stromal reaction.
  • Extensive tissue sampling and immunostaining are recommended to distinguish cases with an extensive smooth muscle component from morphologically similar but benign lesions including angiomyolipoma, leiomyoma, or mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Kidney Neoplasms / pathology. Muscle, Smooth / pathology. Stromal Cells / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Chromosome Deletion. Chromosomes, Human, Pair 3. Disease-Free Survival. Female. Humans. In Situ Hybridization, Fluorescence. Male. Microscopy, Electron, Transmission. Middle Aged. Nephrectomy


64. Ferraro TN, Golden GT, Dahl JP, Smith GG, Schwebel CL, MacDonald R, Lohoff FW, Berrettini WH, Buono RJ: Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer. Epilepsia; 2007 Sep;48(9):1667-77
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  • [Title] Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer.
  • A gene transfer strategy involving a bacterial artificial chromosome (BAC) DNA construct that contains several candidate genes from the critical interval was used to test the hypothesis that a strain-specific variation in one (or more) of the genes is responsible for the QTL effect.
  • Seizure susceptibility was quantified by measuring maximal electroshock seizure threshold (MEST) in transgenic mice and nontransgenic littermates.
  • RESULTS: Seizure testing documented significant MEST elevation in all three transgenic lines compared to littermate controls.

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  • (PMID = 17521350.001).
  • [ISSN] 0013-9580
  • [Journal-full-title] Epilepsia
  • [ISO-abbreviation] Epilepsia
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / NS040554
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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65. Agarwal R, Levinson AW, Schowinsky J, Su LM: Large mixed epithelial and stromal tumor of the kidney masquerading as metastatic renal cell carcinoma. Urology; 2007 Nov;70(5):1008.e17-9
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  • [Title] Large mixed epithelial and stromal tumor of the kidney masquerading as metastatic renal cell carcinoma.
  • We report the case of a 39-year-old woman with a large right renal mass 20 cm in size with heterogeneous solid and cystic components as well as concurrent liver lesions suspicious for metastatic renal cell carcinoma.
  • Surgical extirpation of the renal mass and liver lesions was performed laparoscopically with the pathological analysis revealing a rare renal neoplasm--mixed epithelial and stromal tumor of the kidney--and adenomas of the liver.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Liver Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans


66. Diplas AI, Lambertini L, Lee MJ, Sperling R, Lee YL, Wetmur J, Chen J: Differential expression of imprinted genes in normal and IUGR human placentas. Epigenetics; 2009 May 16;4(4):235-40
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  • Using placental tissue from ten normal and seven IUGR pregnancies, we conducted a systematic survey of the expression of a panel of 74 "putatively" imprinted genes using quantitative RT-PCR.
  • Some genes exhibited frequent LOI in placentas regardless of the disease status (IGF2, TP73, MEST, SLC22A18, PEG3), while others exhibited LOI only in IUGR placentas (PLAGL1, DLK1, H19, SNRPN).

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  • (PMID = 19483473.001).
  • [ISSN] 1559-2308
  • [Journal-full-title] Epigenetics
  • [ISO-abbreviation] Epigenetics
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / N01 AI50028; United States / NIEHS NIH HHS / ES / P50 ES09584; United States / NIAID NIH HHS / AI / U19 AI06231
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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67. Lui JC, Finkielstain GP, Barnes KM, Baron J: An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs. Am J Physiol Regul Integr Comp Physiol; 2008 Jul;295(1):R189-96
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  • In mammals, somatic growth is rapid in early postnatal life but decelerates with age and eventually halts, thus determining the adult body size of the species.
  • For these genes, Igf2, H19, Plagl1, Mest, Peg3, Dlk1, Gtl2, Grb10, Ndn, Cdkn1c, and SLC38a4, the declines show a temporal pattern similar to the decline in growth rate.
  • Contrary to this hypothesis, the methylation status of the promoter regions of Mest, Peg3, and Plagl1 did not change with age.
  • Our findings suggest that a set of growth-regulating imprinted genes is expressed at high levels in multiple tissues in early postnatal life, contributing to rapid somatic growth, but that these genes are subsequently downregulated in multiple tissues simultaneously, contributing to coordinate growth deceleration and cessation, thus imposing a fundamental limit on adult body size.

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  • [Cites] J Biol Chem. 1998 Jan 9;273(2):720-8 [9422723.001]
  • [Cites] Bioessays. 1997 Oct;19(10):839-42 [9363677.001]
  • [Cites] Hum Genet. 1999 Mar;104(3):205-10 [10323243.001]
  • [Cites] J Pediatr Orthop. 1999 May-Jun;19(3):398-403 [10344328.001]
  • [Cites] Nat Genet. 1999 Oct;23(2):199-202 [10508517.001]
  • [Cites] Exp Cell Res. 1964 Oct;36:111-23 [14222732.001]
  • [Cites] Med Sci (Paris). 2005 Apr;21(4):390-5 [15811304.001]
  • [Cites] Clin Chim Acta. 2006 Jan;363(1-2):83-94 [16165119.001]
  • [Cites] Am J Physiol Cell Physiol. 2006 Jan;290(1):C305-12 [16148032.001]
  • [Cites] Cytogenet Genome Res. 2006;113(1-4):279-91 [16575191.001]
  • [Cites] Horm Res. 2006;65 Suppl 3:50-8 [16612114.001]
  • [Cites] Dev Cell. 2006 Nov;11(5):711-22 [17084362.001]
  • [Cites] J Pathol. 2007 Feb;211(3):261-8 [17177177.001]
  • [Cites] BMC Dev Biol. 2007;7:53 [17517131.001]
  • [Cites] Endocrinology. 2008 Apr;149(4):1820-8 [18174286.001]
  • [Cites] Oncogene. 1999 Dec 9;18(52):7527-34 [10602511.001]
  • [Cites] J Biochem. 2000 Jan;127(1):73-83 [10731669.001]
  • [Cites] Hum Mol Genet. 2000 Dec 12;9(20):3101-10 [11115855.001]
  • [Cites] Crit Rev Eukaryot Gene Expr. 2000;10(3-4):241-57 [11272467.001]
  • [Cites] J Biol Chem. 2001 Mar 23;276(12):8674-80 [11124954.001]
  • [Cites] Genomics. 2002 Apr;79(4):530-8 [11944985.001]
  • [Cites] Gene. 2002 Jun 12;292(1-2):101-12 [12119104.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8292-7 [12829789.001]
  • [Cites] Biotechniques. 2003 Jul;35(1):146-50 [12866414.001]
  • [Cites] Front Biosci. 2004 Jan 1;9:603-18 [14766395.001]
  • [Cites] Pflugers Arch. 2004 Feb;447(5):784-95 [12845534.001]
  • [Cites] Dev Biol. 1965 Dec;12(3):451-66 [5884354.001]
  • [Cites] J Anat. 1970 Mar;106(Pt 2):349-70 [5442228.001]
  • [Cites] Acta Anat (Basel). 1972;82(3):305-6 [5048601.001]
  • [Cites] J Clin Invest. 1981 Nov;68(5):1321-30 [7028787.001]
  • [Cites] Trends Genet. 1991 Feb;7(2):45-9 [2035190.001]
  • [Cites] Growth Dev Aging. 1991 Spring;55(1):11-8 [1677931.001]
  • [Cites] J Reconstr Microsurg. 1992 Mar;8(2):93-100 [1564687.001]
  • [Cites] Nature. 1995 May 4;375(6526):34-9 [7536897.001]
  • [Cites] Genes Dev. 1995 Mar 15;9(6):650-62 [7729684.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3026-30 [8610162.001]
  • [Cites] J Clin Endocrinol Metab. 1996 May;81(5):1927-32 [8626859.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11757-62 [8876210.001]
  • [Cites] Genes Dev. 1997 Apr 15;11(8):973-83 [9136926.001]
  • [Cites] Nature. 1997 May 8;387(6629):151-8 [9144284.001]
  • [Cites] EMBO J. 1997 May 15;16(10):2814-25 [9184226.001]
  • [Cites] Cancer Res. 1998 Dec 1;58(23):5489-94 [9850084.001]
  • (PMID = 18448610.001).
  • [ISSN] 0363-6119
  • [Journal-full-title] American journal of physiology. Regulatory, integrative and comparative physiology
  • [ISO-abbreviation] Am. J. Physiol. Regul. Integr. Comp. Physiol.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger
  • [Other-IDs] NLM/ PMC2494817
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68. Kuroda N, Sakaida N, Kinoshita H, Matsuda T, Hes O, Michal M, Okamoto S, Nagashima Y, Tanaka Y: Carcinosarcoma arising in mixed epithelial and stromal tumor of the kidney. APMIS; 2008 Nov;116(11):1013-5
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  • [Title] Carcinosarcoma arising in mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Carcinosarcoma / pathology. Kidney Neoplasms / pathology. Mixed Tumor, Malignant / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Fatal Outcome. Female. Humans. Middle Aged. Nephrectomy. Stromal Cells / pathology

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  • (PMID = 19133001.001).
  • [ISSN] 1600-0463
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Denmark
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69. Karnros MM: [Macabre studies behind Gericault's most known work]. Lakartidningen; 2006 Feb 8-14;103(6):395
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  • [Transliterated title] Makabra studier bakom Géricaults mest kända verk.

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  • (PMID = 16536050.001).
  • [ISSN] 0023-7205
  • [Journal-full-title] Läkartidningen
  • [ISO-abbreviation] Lakartidningen
  • [Language] swe
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits
  • [Publication-country] Sweden
  • [Personal-name-as-subject] Gericault T
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70. Kalinichev M, Starr KR, Teague S, Bradford AM, Porter RA, Herdon HJ: Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test. Brain Res; 2010 May 17;1331:105-13
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  • [Title] Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test.
  • In the present study we tested several glycine transporter 1 (GlyT1) inhibitors including NFPS, SSR 504734, Lu AA21279, Org 25935, SB-710622, GSK931145, as well as the glycine agonist d-serine, in the maximal electroshock threshold (MEST) test in the rat.
  • SB-710622 and GSK931145 had lower minimum effective doses (MEDs) in the MEST test than other GlyT1 inhibitors.

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20303337.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / 2-(N-bis(2-methoxyethyl)amino)butyric acid,2',6'-dimethoxyphenyl ester hydrobromide; 0 / Anticonvulsants; 0 / Benzamides; 0 / GSK 931145; 0 / Glycine Plasma Membrane Transport Proteins; 0 / Phenols; 0 / Slc6a9 protein, rat; TE7660XO1C / Glycine
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71. Stroick M, Alonso A, Fatar M, Griebe M, Kreisel S, Kern R, Gaud E, Arditi M, Hennerici M, Meairs S: Effects of simultaneous application of ultrasound and microbubbles on intracerebral hemorrhage in an animal model. Ultrasound Med Biol; 2006 Sep;32(9):1377-82
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  • Microbubble-enhanced sonothrombolysis (MEST) may be an alternative therapeutic option in ischemic stroke.
  • Clinical study of the efficacy of MEST as an adjunct stroke therapy, before imaging with CT or MRI, requires experimental data on the safety of this approach in the presence of hemorrhagic stroke.
  • This finding provides support for the use of MEST as an early stroke therapy.

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  • (PMID = 16965978.001).
  • [ISSN] 0301-5629
  • [Journal-full-title] Ultrasound in medicine & biology
  • [ISO-abbreviation] Ultrasound Med Biol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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72. Algaba F: Editorial comment on: cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? Eur Urol; 2008 Dec;54(6):1245-6
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  • [Title] Editorial comment on: cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity?
  • [MeSH-major] Kidney Neoplasms / classification. Kidney Neoplasms / pathology

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  • [CommentOn] Eur Urol. 2008 Dec;54(6):1237-46 [18006141.001]
  • (PMID = 18006142.001).
  • [ISSN] 0302-2838
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] Switzerland
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73. Arslan AA, Gold LI, Mittal K, Suen TC, Belitskaya-Levy I, Tang MS, Toniolo P: Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review. Hum Reprod; 2005 Apr;20(4):852-63
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  • [Title] Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review.
  • BACKGROUND: Uterine leiomyomas are extremely common and a major cause of pelvic pain, bleeding, infertility, and the leading indication for hysterectomy.
  • A comparative analysis including eight previous gene expression studies revealed eight prominent genes (ADH1, ATF3, CRABP2, CYR61, DPT, GRIA2, IGF2, MEST) identified by at least five different studies, eleven genes (ALDH1, CD24, CTGF, DCX, DUSP1, FOS, GAGEC1, IGFBP6, PTGDS, PTGER3, TYMS) reported by four studies, twelve genes (ABCA, ANXA1, APM2, CCL21, CDKN1A, CRMP1, EMP1, ESR1, FY, MAP3K5, TGFBR2, TIMP3) identified by three studies, and 40 genes reported by two different studies.
  • [MeSH-minor] Adult. Down-Regulation. Female. Humans. Middle Aged. Oligonucleotide Array Sequence Analysis. Up-Regulation


74. Halldin J: [Health services and the most vulnerable persons I: Not providing care for the homeless is against the law]. Lakartidningen; 2005 Apr 11-17;102(15):1181
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  • [Transliterated title] Vården och de mest utsatta I: Lagstridigt att inte ge utsatta vård.


75. Toledo MS, Tagliari L, Suzuki E, Silva CM, Straus AH, Takahashi HK: Effect of anti-glycosphingolipid monoclonal antibodies in pathogenic fungal growth and differentiation. Characterization of monoclonal antibody MEST-3 directed to Manpalpha1--&gt;3Manpalpha1--&gt;2IPC. BMC Microbiol; 2010;10:47
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  • [Title] Effect of anti-glycosphingolipid monoclonal antibodies in pathogenic fungal growth and differentiation. Characterization of monoclonal antibody MEST-3 directed to Manpalpha1-->3Manpalpha1-->2IPC.
  • RESULTS: In this paper, we describe a detailed characterization of an IgG2a monoclonal antibody (mAb), termed MEST-3, directed to the Paracoccidioides brasiliensis glycolipid antigen Pb-2 (Manpalpha1-->3Manpalpha1-->2IPC).
  • mAb MEST-3 also recognizes GIPCs bearing the same structure in other fungi.
  • Studies performed on fungal cultures clearly showed the strong inhibitory activity of MEST-3 on differentiation and colony formation of Paracoccidioides brasiliensis, Histoplasma capsulatum and Sporothrix schenckii.
  • Similar inhibitory results were observed when these fungi where incubated with a different mAb, which recognizes GIPCs bearing terminal residues of beta-D-galactofuranose linked to mannose (mAb MEST-1).
  • On the other hand, mAb MEST-2 specifically directed to fungal glucosylceramide (GlcCer) was able to promote only a weak inhibition on fungal differentiation and colony formation.

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  • [Cites] Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3254-9 [10716729.001]
  • [Cites] Infect Immun. 2000 Dec;68(12):7049-60 [11083830.001]
  • [Cites] Expert Opin Investig Drugs. 2000 Aug;9(8):1787-96 [11060777.001]
  • [Cites] Biochem Biophys Res Commun. 2001 Jan 12;280(1):19-24 [11162471.001]
  • [Cites] FEBS Lett. 2001 Mar 23;493(1):50-6 [11278004.001]
  • [Cites] Glycobiology. 2001 Feb;11(2):105-12 [11287397.001]
  • [Cites] Glycobiology. 2001 Feb;11(2):113-24 [11287398.001]
  • [Cites] J Endod. 2001 Feb;27(2):107-9 [11491632.001]
  • [Cites] Glycobiology. 2002 Jul;12(7):409-20 [12122022.001]
  • [Cites] J Lipid Res. 2003 Nov;44(11):2073-88 [12923229.001]
  • [Cites] Biochem J. 2004 Mar 1;378(Pt 2):461-72 [14583095.001]
  • [Cites] J Lipid Res. 1972 Sep;13(5):680-6 [5075512.001]
  • [Cites] Anal Biochem. 1980 Dec;109(2):399-402 [7224165.001]
  • [Cites] Biochemistry. 1984 Nov 6;23(23):5581-8 [6509037.001]
  • [Cites] Biochemistry. 1984 Nov 6;23(23):5589-96 [6509038.001]
  • [Cites] J Lipid Res. 1985 Mar;26(3):338-43 [4039347.001]
  • [Cites] Cancer Res. 1988 Aug 1;48(15):4361-7 [3390832.001]
  • [Cites] Biochim Biophys Acta. 1989 Feb 6;1001(2):185-90 [2917142.001]
  • [Cites] Anal Biochem. 1992 Feb 14;201(1):1-8 [1377883.001]
  • [Cites] J Biol Chem. 1993 Jun 25;268(18):13723-30 [8514804.001]
  • [Cites] J Antibiot (Tokyo). 1993 Sep;46(9):1414-20 [8226319.001]
  • [Cites] J Med Vet Mycol. 1995 Jul-Aug;33(4):247-51 [8531023.001]
  • [Cites] Braz J Med Biol Res. 1995 Aug;28(8):919-23 [8555996.001]
  • [Cites] Biochem Biophys Res Commun. 1996 May 15;222(2):639-45 [8670257.001]
  • [Cites] J Bacteriol. 1996 Nov;178(21):6223-6 [8892822.001]
  • [Cites] J Biol Chem. 1997 Apr 11;272(15):9809-17 [9092515.001]
  • [Cites] Glycobiology. 1997 Jun;7(4):463-8 [9184826.001]
  • [Cites] Braz J Med Biol Res. 1997 Mar;30(3):395-9 [9246238.001]
  • [Cites] Biochemistry. 1998 Jun 16;37(24):8764-75 [9628738.001]
  • [Cites] Biochemistry. 1999 Jun 1;38(22):7294-306 [10353841.001]
  • [Cites] Curr Drug Targets. 2005 Dec;6(8):895-907 [16375673.001]
  • [Cites] Eukaryot Cell. 2006 Mar;5(3):488-98 [16524904.001]
  • [Cites] Clin Vaccine Immunol. 2007 Feb;14(2):150-6 [17135452.001]
  • [Cites] J Lipid Res. 2007 Aug;48(8):1801-24 [17488996.001]
  • [Cites] Glycobiology. 2008 Jan;18(1):84-96 [17971386.001]
  • [Cites] Biochim Biophys Acta. 2008 Mar;1780(3):362-9 [17976917.001]
  • [Cites] Ann Clin Microbiol Antimicrob. 2009;8:13 [19402910.001]
  • [Cites] An Acad Bras Cienc. 2009 Sep;81(3):477-88 [19722017.001]
  • [Cites] Mol Gen Genet. 2000 Sep;264(1-2):64-74 [11016834.001]
  • (PMID = 20156351.001).
  • [ISSN] 1471-2180
  • [Journal-full-title] BMC microbiology
  • [ISO-abbreviation] BMC Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Fungal; 0 / Antibodies, Monoclonal; 0 / Antigens, Fungal; 0 / Glycosphingolipids; 0 / Immunoglobulin G
  • [Other-IDs] NLM/ PMC2831884
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76. Suzuki S, Renfree MB, Pask AJ, Shaw G, Kobayashi S, Kohda T, Kaneko-Ishino T, Ishino F: Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby. Mech Dev; 2005 Feb;122(2):213-22
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  • [Title] Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby.
  • Imprinted gene orthologues of human and mouse p57(KIP2), IGF2 and PEG1/MEST genes were isolated. p57(KIP2) did not show stable monoallelic expression suggesting that it is not imprinted in marsupials.
  • The differentially methylated region (DMR) of the human and mouse PEG1/MEST promoter is absent in the wallaby.

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  • (PMID = 15652708.001).
  • [ISSN] 0925-4773
  • [Journal-full-title] Mechanisms of development
  • [ISO-abbreviation] Mech. Dev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / CDKN1C protein, human; 0 / Cdkn1c protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p57; 0 / DNA Primers; 0 / DNA, Complementary; 0 / Nuclear Proteins; 0 / Proteins; 0 / mesoderm specific transcript protein; 67763-97-7 / Insulin-Like Growth Factor II
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77. Halldin J: [Health services for the most vulnerable II: What has been done and what should be done?]. Lakartidningen; 2005 Apr 18-24;102(16):1266-7
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  • [Transliterated title] Vården och de mest utsatta Il: Vad har gjorts och vad bör göras?


78. Montironi R, Mazzucchelli R, Lopez-Beltran A, Martignoni G, Cheng L, Montorsi F, Scarpelli M: Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? Eur Urol; 2008 Dec;54(6):1237-46
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  • [Title] Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity?
  • OBJECTIVES: The term "renal epithelial and stromal tumour" (REST) was proposed recently to encompass the spectrum of findings observed in cystic nephroma (CN) and mixed epithelial and stromal tumour (MEST) of the kidney.
  • Our aim was to review the broad spectrum of usual and unusual clinical and morphologic findings observed in CN and MEST.
  • METHODS: Based on Medline database searches, all aspects of CN and MEST were assessed.
  • RESULTS: CN and MEST have a remarkable similarity in sex predilection, age distribution, and morphologic attributes of both the epithelial and stromal components and immunohistochemical profile, albeit with variation in individual categories, with higher prevalence of stromal-to-epithelial ratio, prominent ovarian-like stroma, smaller cysts, and stromal luteinisation in MEST, and large cysts, thin septa, and low stromal-to-epithelial ratio in CN.
  • The stromal component in both lesions expresses estrogen and progesterone receptors.
  • Rare and unusual morphologic features, such as endometrioid, cervical, and intestinal differentiation, and luteinised ovarian-like stroma, have been described in MEST.
  • The epithelial element occasionally shows estrogen and progesterone receptors.
  • Even though an aggressive behaviour has been reported in very few cases, in general both neoplasms are considered benign and surgical excision is curative.
  • [MeSH-major] Kidney Neoplasms / classification. Kidney Neoplasms / pathology

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  • [CommentIn] Eur Urol. 2008 Dec;54(6):1245-6 [18006142.001]
  • [CommentIn] Eur Urol. 2009 Jul;56(1):e3 [19167806.001]
  • (PMID = 18006141.001).
  • [ISSN] 0302-2838
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 50
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79. Koza RA, Nikonova L, Hogan J, Rim JS, Mendoza T, Faulk C, Skaf J, Kozak LP: Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. PLoS Genet; 2006 May;2(5):e81
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  • In particular, elevated expression of SFRP5, an inhibitor of Wnt signaling, the imprinted gene MEST and BMP3 may be causally linked to fat mass expansion, since differences in gene expression observed in biopsies of epididymal fat at 7 wk of age (before the high-fat diet) correlated with adiposity after 8 wk on a high-fat diet.

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  • [Cites] Nat Cell Biol. 2001 Mar;3(3):267-75 [11231576.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3802-7 [11274398.001]
  • [Cites] Hum Mol Genet. 2001 Apr 1;10(8):807-14 [11285246.001]
  • [Cites] FASEB J. 2001 Aug;15(10):1840-2 [11481248.001]
  • [Cites] Nature. 2001 Dec 13;414(6865):799-806 [11742412.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E834-42 [11882503.001]
  • [Cites] Eur J Cell Biol. 2002 Apr;81(4):222-30 [12018390.001]
  • [Cites] Curr Opin Clin Nutr Metab Care. 2002 Jul;5(4):385-9 [12107373.001]
  • [Cites] Science. 2002 Aug 2;297(5582):843-5 [12161655.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10730-5 [12149466.001]
  • [Cites] J Biol Chem. 2002 Aug 23;277(34):30998-1004 [12055200.001]
  • [Cites] Biochim Biophys Acta. 2003 Jan 3;1625(1):36-42 [12527424.001]
  • [Cites] J Clin Invest. 2003 Feb;111(3):399-407 [12569166.001]
  • [Cites] Science. 2003 Feb 7;299(5608):853-5 [12574618.001]
  • [Cites] Science. 2003 Feb 7;299(5608):856-8 [12574619.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2538-43 [12601169.001]
  • [Cites] J Cell Sci. 2003 Jul 1;116(Pt 13):2627-34 [12775774.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2003 Jul;285(1):R183-92 [12609816.001]
  • [Cites] Physiol Genomics. 2003 Jul 7;14(2):139-47 [12746468.001]
  • [Cites] Diabetes. 2003 Aug;52(8):1958-66 [12882911.001]
  • [Cites] Genome Res. 2003 Sep;13(9):2129-41 [12952881.001]
  • [Cites] Circ Res. 2003 Oct 31;93(9):e88-97 [14525808.001]
  • [Cites] J Biol Chem. 2003 Nov 14;278(46):45969-77 [12925529.001]
  • [Cites] Diabetes. 2004 Feb;53(2):336-46 [14747283.001]
  • [Cites] Dev Cell. 2004 Apr;6(4):483-95 [15068789.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E891-5 [14749209.001]
  • [Cites] J Cell Sci. 2004 Jun 1;117(Pt 13):2853-64 [15169841.001]
  • [Cites] J Biol Chem. 2004 Jul 9;279(28):29558-64 [15123608.001]
  • [Cites] FASEB J. 2004 Aug;18(11):1282-4 [15208271.001]
  • [Cites] J Biol Chem. 2004 Aug 20;279(34):35503-9 [15190075.001]
  • [Cites] Obes Res. 2004 Aug;12(8):1264-70 [15340109.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E738-44 [12217891.001]
  • [Cites] Development. 2004 Oct;131(19):4725-34 [15329348.001]
  • [Cites] Annu Rev Cell Dev Biol. 2004;20:781-810 [15473860.001]
  • [Cites] Gene. 2004 Oct 27;341:19-39 [15474285.001]
  • [Cites] Int J Obes Relat Metab Disord. 2004 Nov;28(11):1357-64 [15356668.001]
  • [Cites] Cell. 1983 Dec;35(3 Pt 2):657-66 [6686086.001]
  • [Cites] J Appl Physiol (1985). 1988 Mar;64(3):1249-56 [3284871.001]
  • [Cites] Diabetes. 1988 Sep;37(9):1163-7 [3044882.001]
  • [Cites] N Engl J Med. 1990 May 24;322(21):1477-82 [2336074.001]
  • [Cites] N Engl J Med. 1990 May 24;322(21):1483-7 [2336075.001]
  • [Cites] Am J Physiol. 1991 Jun;260(6 Pt 2):R1104-13 [2058738.001]
  • [Cites] Science. 1992 Apr 17;256(5055):379-82 [1566086.001]
  • [Cites] Diabetologia. 1993 Jan;36(1):62-7 [8436255.001]
  • [Cites] Mol Endocrinol. 1994 Apr;8(4):518-27 [7914350.001]
  • [Cites] N Engl J Med. 1995 Mar 9;332(10):621-8 [7632212.001]
  • [Cites] Metabolism. 1995 May;44(5):645-51 [7752914.001]
  • [Cites] Annu Rev Biochem. 1995;64:345-73 [7574486.001]
  • [Cites] Am J Physiol. 1996 May;270(5 Pt 1):E768-75 [8967464.001]
  • [Cites] Int J Obes Relat Metab Disord. 1996 Jun;20(6):501-6 [8782724.001]
  • [Cites] Behav Genet. 1997 Jul;27(4):325-51 [9519560.001]
  • [Cites] Diabetes. 2004 Dec;53(12):3097-106 [15561939.001]
  • [Cites] Diabetes. 2004 Dec;53(12):3274-85 [15561960.001]
  • [Cites] J Physiol. 2004 Dec 1;561(Pt 2):355-77 [15459241.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E117-24 [15353408.001]
  • [Cites] Diabetologia. 2005 Jan;48(1):123-31 [15624093.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3324-9 [15728361.001]
  • [Cites] Obes Res. 2005 Mar;13(3):381-490 [15833932.001]
  • [Cites] Biochim Biophys Acta. 2005 May 30;1740(2):287-92 [15949695.001]
  • [Cites] J Biol Chem. 2005 Jun 24;280(25):24004-10 [15849360.001]
  • [Cites] J Cell Biochem. 2005 Aug 15;95(6):1135-45 [15962287.001]
  • [Cites] Cell Metab. 2005 Jun;1(6):371-8 [16054086.001]
  • [Cites] Crit Rev Biochem Mol Biol. 2005 Jul-Aug;40(4):229-42 [16126487.001]
  • [Cites] Int J Obes Relat Metab Disord. 1999 Nov;23(11):1105-17 [10578199.001]
  • [Cites] Biosci Biotechnol Biochem. 1999 Oct;63(10):1749-55 [10586503.001]
  • [Cites] Nature. 2000 Apr 6;404(6778):644-51 [10766251.001]
  • [Cites] J Clin Invest. 2000 May;105(10):1345-52 [10811842.001]
  • [Cites] J Biol Chem. 2000 Jul 7;275(27):20896-902 [10777495.001]
  • [Cites] Science. 2000 Aug 11;289(5481):950-3 [10937998.001]
  • [Cites] Physiol Genomics. 2000 Aug 9;3(2):113-20 [11015606.001]
  • [Cites] Science. 2000 Oct 6;290(5489):134-8 [11021798.001]
  • [Cites] Nature. 2000 Sep 28;407(6803):535-8 [11029008.001]
  • [Cites] Annu Rev Cell Dev Biol. 2000;16:145-71 [11031233.001]
  • [Cites] J Biol Chem. 2000 Nov 3;275(44):34486-92 [10931824.001]
  • [Cites] Nat Genet. 2001 Jan;27(1):84-8 [11138004.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):2005-10 [11172066.001]
  • [Cites] J Clin Invest. 1997 Feb 1;99(3):385-90 [9022070.001]
  • (PMID = 16733553.001).
  • [ISSN] 1553-7404
  • [Journal-full-title] PLoS genetics
  • [ISO-abbreviation] PLoS Genet.
  • [Language] eng
  • [Databank-accession-numbers] GEO/ GSE4692/ GSE4697
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK072476; United States / NIDDK NIH HHS / DK / P-30 DK072476
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / Sfrp5 protein, mouse
  • [Other-IDs] NLM/ PMC1464831
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80. Takabatake M, Takuwa Y, Takuwa N, Yasuno H, Matsumoto S, Shibutani M, Mitsumori K: A case report of a renal mixed epithelial and stromal tumor in a heterozygous S1P2 receptor deficient mouse. J Vet Med Sci; 2008 May;70(5):483-5
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  • [Title] A case report of a renal mixed epithelial and stromal tumor in a heterozygous S1P2 receptor deficient mouse.
  • We report a case of mixed epithelial and stromal tumor of the kidney (MESTK) in a 32-week-old heterozygous sphingosine 1-phosphate-2 (S1P2) receptor deficient female mouse.
  • A white solid mass replacing the left kidney was observed at the left retroperitoneal wall.
  • Histologically, the tumor mass consisted of dimorphic cellular components of epithelial and stromal cells.
  • Epithelial cells formed various sized irregular-shaped tubular structures resembling renal tubules surrounded by stromal cells.
  • Immunohistochemically, epithelial cells were positive for cytokeratin, while stromal cells showed positive immunoreactivity with alpha-smooth muscle actin as well as vimentin.
  • Based on the morphological and immunohistochemical findings, this tumor was diagnosed as a MESTK.

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  • (PMID = 18525171.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Receptors, Lysosphingolipid; P8M1T4190R / Ethylnitrosourea
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81. Huang YJ, Huang X, Shi XY, Lu J: [Pathological characteristics mixed epithelial and stromal tumor of kidney]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):415-8
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  • [Title] [Pathological characteristics mixed epithelial and stromal tumor of kidney].
  • OBJECTIVE: To study the clinicopathological features of mixed epithelial and stromal tumor of the kidney(MESTK).
  • RESULTS: A case of MESTK which uncommonly occurred in a 16-year old adolescent male presented with dysuria and a large mass in the right renal region without a history of estrogen/progestogen treatment and/or obesity or urogenital surgery.
  • Radiology revealed a large cystic/solid mass within the right kidney.
  • Microscopically, the tumor was composed of a mixture of stromal and epithelial components.
  • The epithelial component was composed of flat to columnar cells forming glands or tubules.
  • The stromal components essentially consisted of bland, loosely packed spindle cells in an edematous and myxoid background.
  • Immunohistochemical staining revealed that the epithelial components were positive for AE1/AE3 and focally positive for estrogen receptor (ER),progesterone receptor(PR), CD10 and Vimentin, whereas the stromal components were positive for ER, PR, Desmin and smooth muscle actin(SMA).
  • Both epithelial and stromal components were negative for HMB-45, S-100, alpha-inhibin and WT-T.
  • CONCLUSION; MESTK occurred in a pubertal male, as in the current case, supports the hypothesis that proliferation of remnants of the primitive mesenchyme in the kidney in situation of sex-steroid abnormity may play an important role in the pathogenesis of male MESTK.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology

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  • (PMID = 18677391.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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82. Kamei Y, Suganami T, Kohda T, Ishino F, Yasuda K, Miura S, Ezaki O, Ogawa Y: Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner. FEBS Lett; 2007 Jan 9;581(1):91-6
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  • [Title] Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.
  • Paternally expressed 1 (Peg1)/mesoderm specific transcript (Mest) is an imprinted gene, which is only transcribed from the paternal (father's) allele.
  • In some human cancer tissues, an alternatively spliced variant of PEG1/MEST mRNA using a different promoter of a distinct first exon is expressed from both paternal and maternal alleles.
  • We previously reported that Peg1/Mest expression was markedly up-regulated in obese adipose tissue in mice.
  • Moreover, transgenic overexpression of Peg1/Mest in the adipose tissue resulted in the enlargement of adipocytes in size.
  • Given the potential pathophysiologic relevance in obesity, we examined the nature of increased expression of Peg1/Mest in obese adipose tissue.
  • In obese adipose tissue, expression of Peg1/Mest was increased, but not that of other imprinted genes tested.
  • The transcription rate of Peg1/Mest was increased in obese adipose tissue.
  • We found at least four isoforms of mouse Peg1/Mest generated by use of the alternative first exons.
  • We also demonstrated that the abundantly expressed Peg1/Mest in obese adipose tissue retained monoallelic expression.
  • This is the first report of monoallelic induction of Peg1/Mest in adult tissues.

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  • (PMID = 17182038.001).
  • [ISSN] 0014-5793
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Protein Isoforms; 0 / Proteins; 0 / mesoderm specific transcript protein
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83. Large MC, Al-Ahmadie H, Shalhav AL, Zorn KC: Mixed epithelial stromal renal tumor with dystrophic ossification: a case report and literature review. Can J Urol; 2009 Jun;16(3):4690-3
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  • [Title] Mixed epithelial stromal renal tumor with dystrophic ossification: a case report and literature review.
  • A 25-year-old female presented with worsening right flank pain and a 9 year history of a slow growing 4 centimeter calcified renal mass.
  • The lesion was resected by laparoscopic partial nephrectomy revealing a mixed epithelial and stromal tumor (MEST).
  • This tumor has unusual features including the extensive amount of dystrophic calcification and the young age at presentation.
  • [MeSH-major] Kidney Neoplasms / surgery. Laparoscopy. Neoplasms, Glandular and Epithelial / surgery. Nephrectomy / methods. Ossification, Heterotopic / surgery
  • [MeSH-minor] Adult. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 19497183.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 22
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84. Boman J, Nylander E: [Chlamydia decreasing mostly in Västerbotten--why?]. Lakartidningen; 2010 Mar 31-Apr 13;107(13-14):920-1
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  • [Transliterated title] Klamydia minskar mest i Västerbotten--varför det?
  • [MeSH-minor] Adult. Female. Humans. Incidence. Male. Primary Prevention. Secondary Prevention. Sweden / epidemiology. Young Adult

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  • (PMID = 20432868.001).
  • [ISSN] 0023-7205
  • [Journal-full-title] Läkartidningen
  • [ISO-abbreviation] Lakartidningen
  • [Language] swe
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
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85. Ihlebaek C, Laerum E: [Hits most, costs most and gets least]. Tidsskr Nor Laegeforen; 2010 Nov 4;130(21):2106
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  • [Transliterated title] Rammer flest, koster mest og får minst.

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  • (PMID = 21052101.001).
  • [ISSN] 0807-7096
  • [Journal-full-title] Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
  • [ISO-abbreviation] Tidsskr. Nor. Laegeforen.
  • [Language] nor
  • [Publication-type] Editorial
  • [Publication-country] Norway
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86. Parikh P, Chan TY, Epstein JI, Argani P: Incidental stromal-predominant mixed epithelial-stromal tumors of the kidney: a mimic of intraparenchymal renal leiomyoma. Arch Pathol Lab Med; 2005 Jul;129(7):910-4
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  • [Title] Incidental stromal-predominant mixed epithelial-stromal tumors of the kidney: a mimic of intraparenchymal renal leiomyoma.
  • CONTEXT: Mixed epithelial-stromal tumor of the kidney is a recently recognized benign renal tumor that usually occurs in adult women and typically forms a sizable lesion with solid and cystic areas.
  • The recognized morphologic spectrum of this recently described entity is evolving.
  • OBJECTIVE: To review the clinicopathologic features of 3 small mixed epithelial-stromal tumors of the kidney that were incidental findings in kidneys removed for other reasons.
  • DESIGN: The clinical presentation and morphologic findings of the 3 cases were reviewed.
  • RESULTS: All 3 lesions contained predominantly fascicles of smooth muscle mimicking leiomyoma, but they also had cellular subpopulations of smaller, müllerian-appearing stromal cells.
  • Although only the spindled smooth muscle cells were immunoreactive for muscle markers desmin and actin, both the spindled smooth muscle cells and the cellular müllerian-appearing stromal cells demonstrated diffuse nuclear labeling for estrogen and progesterone receptors.
  • CONCLUSIONS: Mixed epithelial-stromal tumor of the kidney may present as an incidental stromal-predominant lesion within the kidney.
  • Such lesions are easily confused with leiomyomas or stromal-predominant angiomyolipomas.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Leiomyoma / diagnosis. Neoplasms, Complex and Mixed / diagnosis. Neoplasms, Glandular and Epithelial / diagnosis. Smooth Muscle Tumor / diagnosis. Stromal Cells / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 15974815.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Paese K, Jäger A, Poletto FS, Pinto EF, Rossi-Bergmann B, Pohlmann AR, Guterres SS: Semisolid formulation containing a nanoencapsulated sunscreen: effectiveness, in vitro photostability and immune response. J Biomed Nanotechnol; 2009 Jun;5(3):240-6
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  • In parallel, the immune response of the nanostructured system was evaluated by mouse ear swelling test and the local lymph node assay.
  • Formulations did not induce increases higher than 10% in ear swelling, indicating that the hydrogels did not cause cutaneous sensitization in mice.

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  • (PMID = 20055005.001).
  • [ISSN] 1550-7033
  • [Journal-full-title] Journal of biomedical nanotechnology
  • [ISO-abbreviation] J Biomed Nanotechnol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drug Carriers; 0 / Powders; 0 / Sunscreening Agents
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88. Kim Y, Kim SS, Kim G, Park S, Park IS, Yoo HW: Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays. Clin Genet; 2005 Mar;67(3):267-9
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  • [Title] Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays.

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  • (PMID = 15691366.001).
  • [ISSN] 0009-9163
  • [Journal-full-title] Clinical genetics
  • [ISO-abbreviation] Clin. Genet.
  • [Language] eng
  • [Publication-type] Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / GRB10 protein, human; 0 / Proteins; 0 / mesoderm specific transcript protein; 151441-47-3 / GRB10 Adaptor Protein
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89. Ya'u J, Yaro AH, Abubakar MS, Anuka JA, Hussaini IM: Anticonvulsant activity of Carissa edulis (Vahl) (Apocynaceae) root bark extract. J Ethnopharmacol; 2008 Nov 20;120(2):255-8
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  • The anticonvulsant activity of the extract was assessed in pentylenetetrazole (PTZ)-induced convulsion in mice and maximal electroshock test (MEST) in chicks, with benzodiazepine and phenytoin as standard drugs, respectively.
  • Carissa edulis exhibited dose-dependent inhibition of the convulsion induced by MEST with 20mg/kg providing 90% protection while phenytoin (20mg/kg) produced 100% protection.
  • [MeSH-minor] Administration, Oral. Animals. Chickens. Disease Models, Animal. Dose-Response Relationship, Drug. Female. Flumazenil / pharmacology. Injections, Intraperitoneal. Lethal Dose 50. Male. Mice. Naloxone / pharmacology. Phenytoin / pharmacology. Plant Bark. Plant Roots. Toxicity Tests, Acute

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  • (PMID = 18822365.001).
  • [ISSN] 0378-8741
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Plant Extracts; 36B82AMQ7N / Naloxone; 40P7XK9392 / Flumazenil; 6158TKW0C5 / Phenytoin
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90. Fretheim A: [Most help to the needest]. Tidsskr Nor Laegeforen; 2005 Mar 17;125(6):715
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  • [Transliterated title] Mest hjelp der behovet er størst.

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  • (PMID = 15776062.001).
  • [ISSN] 0807-7096
  • [Journal-full-title] Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
  • [ISO-abbreviation] Tidsskr. Nor. Laegeforen.
  • [Language] nor
  • [Publication-type] Editorial
  • [Publication-country] Norway
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91. Thyavihally YB, Tongaonkar HB, Desai SB: Benign mixed epithelial stromal tumor of the renal pelvis with exophytic growth: case report. Int Semin Surg Oncol; 2005 Sep 9;2:18
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  • [Title] Benign mixed epithelial stromal tumor of the renal pelvis with exophytic growth: case report.
  • BACKGROUND: Mixed epithelial and stromal tumor (MEST) is a distinctive benign composite neoplasm of the kidney predominantly seen in females mostly in the perimenopausal period.
  • A computed tomography scan of abdomen and pelvis showed a 9 x 7 cm uniformly solid mass with poor contrast enhancement situated in the inferomedial aspect of the left kidney.
  • The mass was excised preserving the kidney.
  • Microscopically, the tumor was composed of large collagenized areas containing bundles of spindle cells and several 'microcysts' lined by cuboidal epithelium suggestive of a benign mixed epithelial stromal tumor.
  • DISCUSSION: Mixed epithelial tumors usually present in perimenopausal women as a partially cystic mass.
  • Tumors are composed of irregular mixtures of cystic and solid areas, glands with variable complexity and distribution and the stromal component is characterized by a spindle cell proliferation.
  • CONCLUSION: MEST is a distinctive benign tumor of the kidney that should be distinguished from other renal neoplasms.
  • MEST arising from the renal pelvis and growing exophytically is a rare entity.

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  • [Cites] Lancet Oncol. 2004 Dec;5(12):747-9 [15581546.001]
  • [Cites] Am J Surg Pathol. 2000 Jul;24(7):958-70 [10895818.001]
  • [Cites] Hum Pathol. 2001 May;32(5):513-20 [11381370.001]
  • [Cites] Virchows Arch. 2001 Nov;439(5):700-2 [11764393.001]
  • [Cites] Semin Diagn Pathol. 1998 Feb;15(1):2-20 [9503503.001]
  • [Cites] Hinyokika Kiyo. 2004 Jan;50(1):49-52 [15032017.001]
  • [Cites] Pathologe. 2004 Sep;25(5):356-61 [15127227.001]
  • [Cites] Virchows Arch. 2004 Oct;445(4):359-67 [15322873.001]
  • [Cites] Pathol Res Pract. 1998;194(6):445-8 [9689654.001]
  • [Cites] Adv Anat Pathol. 2003 Jul;10(4):223-33 [12826829.001]
  • (PMID = 16150156.001).
  • [ISSN] 1477-7800
  • [Journal-full-title] International seminars in surgical oncology : ISSO
  • [ISO-abbreviation] Int Semin Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1215508
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92. Teshome K, Gebre-Mariam T, Asres K, Perry F, Engidawork E: Toxicity studies on dermal application of plant extract of Plumbago zeylanica used in Ethiopian traditional medicine. J Ethnopharmacol; 2008 May 8;117(2):236-48
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  • To this effect, the dermatotoxicity of 80% methanol extract of the root part of Plumbago zeylanica was investigated in animals following standard procedures for irritation, sensitization, acute toxicity and repeated toxicity tests.
  • The skin irritation test on rabbits showed Plumbago zeylanica extract to be a moderate irritant, with a primary irritation index of 2.00.
  • Sensitization test on mice by the Mouse Ear Swelling Test method revealed the extract to be non-sensitizer in a dose range of 4-10mg/ml and the percent responder was zero.
  • Acute dermal toxicity test on rats did not produce any overt signs of toxicity, except that there was a weight gain difference between the test and control groups of female rats.
  • Repeated dose toxicity test was associated with increased relative testis weight (P<0.05) as well as higher values for Blood urea nitrogen and K+ (P<0.05) in both sexes with the highest dose (1000 mg/kg) group, although histopathological analyses failed to lend support to these observations.
  • Taken together, the dermatotoxicity test results from this study suggest that Plumbago zeylanica toxic effects might be limited to effects like moderate irritation.

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  • (PMID = 18339496.001).
  • [ISSN] 0378-8741
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Irritants; 0 / Plant Extracts; 0 / Solvents
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93. Cheng L, Yang YP, Zhang SB, Zhu YL, Zhang JM: [Cystic nephroma and mixed epithelial stromal tumor of kidney: evolution of terminology, controversies, pathologic features and differential diagnosis]. Zhonghua Bing Li Xue Za Zhi; 2008 Oct;37(10):707-10
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  • [Title] [Cystic nephroma and mixed epithelial stromal tumor of kidney: evolution of terminology, controversies, pathologic features and differential diagnosis].
  • [MeSH-major] Kidney Neoplasms / diagnosis. Kidney Neoplasms / pathology. Nephroma, Mesoblastic / diagnosis. Nephroma, Mesoblastic / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Kidney / pathology

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  • (PMID = 19094493.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Lectures
  • [Publication-country] China
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94. Koza RA, Rogers P, Kozak LP: Inter-individual variation of dietary fat-induced mesoderm specific transcript in adipose tissue within inbred mice is not caused by altered promoter methylation. Epigenetics; 2009 Oct 1;4(7):512-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mesoderm specific transcript (Mest), an imprinted gene associated with fat mass expansion under conditions of positive energy balance, shows highly variable expression (approximately 80-fold) in white adipose tissue (WAT) of C57BL/6J (B6) mice fed an obesogenic diet.
  • Since B6 mice are essentially genetically invariant and Mest is known to be regulated by CpG methylation within its immediate proximal promoter, the large variability in its expression in adipose tissue has the hallmarks of being controlled via an epigenetic mechanism.
  • In this study, bisulfite sequencing and allelic discrimination analyses were performed to determine whether variations in CpG methylation within the Mest promoter were associated with its expression.
  • Results showed no relationship between CpG methylation in the Mest promoter and high versus low expression in either WAT or isolated adipocytes; and, experiments using a single nucleotide polymorphism in the Mest promoter region between B6 and Castaneus mice showed the expected pattern for an imprinted gene with all maternal alleles being methylated.
  • These data suggest that mechanisms independent of the CpG methylation status of the Mest promoter must underlie the control of its expression during adipose tissue expansion.

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  • [Cites] EMBO J. 1997 Nov 3;16(21):6510-20 [9351832.001]
  • [Cites] Gene. 1999 Jan 21;226(2):199-209 [9931489.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E117-24 [15353408.001]
  • [Cites] PLoS Genet. 2006 May;2(5):e81 [16733553.001]
  • [Cites] FEBS Lett. 2007 Jan 9;581(1):91-6 [17182038.001]
  • [Cites] Int J Obes (Lond). 2008 Sep;32(9):1373-9 [18626486.001]
  • [Cites] FASEB J. 2008 Nov;22(11):3925-37 [18644838.001]
  • [Cites] Mol Biol Cell. 2009 Jan;20(1):296-305 [18923144.001]
  • [Cites] Kobe J Med Sci. 2009;54(5):E241-9 [19628964.001]
  • [Cites] Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E834-42 [11882503.001]
  • [Cites] Am J Physiol Renal Physiol. 2002 May;282(5):F953-65 [11934706.001]
  • [Cites] J Biol Chem. 2002 Apr 19;277(16):13518-27 [11821432.001]
  • [Cites] Curr Protein Pept Sci. 2000 Sep;1(2):209-35 [12369917.001]
  • [Cites] Genesis. 2004 May;39(1):65-72 [15124229.001]
  • [Cites] J Nutr. 1977 Nov;107(11):1969-74 [908953.001]
  • [Cites] J Lipid Res. 1979 Jan;20(1):97-106 [220355.001]
  • [Cites] J Lipid Res. 1984 Apr;25(4):336-47 [6726086.001]
  • [Cites] Protein Eng. 1992 Apr;5(3):197-211 [1409539.001]
  • [Cites] Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2562-6 [8146154.001]
  • [Cites] Nat Genet. 1994 Sep;8(1):59-65 [7987393.001]
  • [Cites] Genetics. 1996 Feb;142(2):557-67 [8852853.001]
  • [Cites] Nucleic Acids Res. 1996 Dec 15;24(24):5064-6 [9016686.001]
  • [Cites] Cell. 1997 Jul 11;90(1):181-92 [9230313.001]
  • [Cites] Genetics. 1997 Oct;147(2):777-86 [9335612.001]
  • [Cites] Hum Mol Genet. 1997 Oct;6(11):1907-15 [9302270.001]
  • (PMID = 19875931.001).
  • [ISSN] 1559-2308
  • [Journal-full-title] Epigenetics
  • [ISO-abbreviation] Epigenetics
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / P20 RR021945; United States / NIDDK NIH HHS / DK / P30 DK072476; United States / NIDDK NIH HHS / DK / R21 DK074951; United States / NCRR NIH HHS / RR / P20-RR021945
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dietary Fats; 0 / Proteins; 0 / mesoderm specific transcript protein
  • [Other-IDs] NLM/ NIHMS559296; NLM/ PMC3951159
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95. Tierling S, Souren NY, Gries J, Loporto C, Groth M, Lutsik P, Neitzel H, Utz-Billing I, Gillessen-Kaesbach G, Kentenich H, Griesinger G, Sperling K, Schwinger E, Walter J: Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human. J Med Genet; 2010 Jun;47(6):371-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Using bisulfite based technologies 10 differentially methylated regions (DMRs) were analysed, including KvDMR1, H19, SNRPN, MEST, GRB10, DLK1/MEG3 IG-DMR, GNAS NESP55, GNAS NESPas, GNAS XL-alpha-s and GNAS Exon1A.
  • The only slightly variable DMR was that of MEST.

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  • (PMID = 19948534.001).
  • [ISSN] 1468-6244
  • [Journal-full-title] Journal of medical genetics
  • [ISO-abbreviation] J. Med. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DLK1 protein, human; 0 / GRB10 protein, human; 0 / H19 long non-coding RNA; 0 / Intercellular Signaling Peptides and Proteins; 0 / KCNQ1OT1 protein, human; 0 / Membrane Proteins; 0 / Potassium Channels, Voltage-Gated; 0 / Proteins; 0 / RNA, Long Noncoding; 0 / RNA, Untranslated; 0 / mesoderm specific transcript protein; 0 / snRNP Core Proteins; 151441-47-3 / GRB10 Adaptor Protein; 9007-49-2 / DNA; EC 3.6.1.- / GNAS protein, human; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gs
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96. Hammoud SS, Purwar J, Pflueger C, Cairns BR, Carrell DT: Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility. Fertil Steril; 2010 Oct;94(5):1728-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTERVENTION(S): The CpG methylation patterns were examined at seven imprinted loci sequenced: LIT1, MEST, SNRPN, PLAGL1, PEG3, H19, and IGF2.
  • When comparing the severity of methylation alterations among infertile patients, the oligozoospermic patients were significantly affected at mesoderm-specific transcript (MEST), whereas abnormal protamine patients were affected at KCNQ1, overlapping transcript 1 (LIT1), and at small nuclear ribonucleoprotein polypeptide N (SNRPN).

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19880108.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / IGF2 protein, human; 0 / KCNQ1OT1 protein, human; 0 / Kruppel-Like Transcription Factors; 0 / PEG3 protein, human; 0 / Potassium Channels, Voltage-Gated; 0 / Protamines; 0 / Proteins; 0 / SNRPN protein, human; 0 / mesoderm specific transcript protein; 0 / snRNP Core Proteins; 67763-97-7 / Insulin-Like Growth Factor II; 9007-49-2 / DNA
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97. Van der Stelt B, Temminghoff EJ, Van Vliet PC, Van Riemsdijk WH: Volatilization of ammonia from manure as affected by manure additives, temperature and mixing. Bioresour Technol; 2007 Dec;98(18):3449-55
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  • Ammonia (NH(3)) volatilization decreases the N-nutrient value of livestock manure slurries and can lead to soil acidification and eutrophication problems.
  • In this study the effect of three manure additives (Euro Mest-mix (Mx), Effective Micro-organisms (EM), and Agri-mest (Am)) on NH(3) volatilization at three temperatures (4, 20, and 35 degrees C) was investigated.

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  • (PMID = 17215124.001).
  • [ISSN] 0960-8524
  • [Journal-full-title] Bioresource technology
  • [ISO-abbreviation] Bioresour. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Gases; 0 / Manure; 7664-41-7 / Ammonia
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98. Li SS, Yu SL, Singh S: Epigenetic states and expression of imprinted genes in human embryonic stem cells. World J Stem Cells; 2010 Aug 26;2(4):97-102
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  • Ten imprinted genes, namely GRB10, PEG10, SGCE, MEST, SDHD, SNRPN, SNURF, NDN, IPW and NESP55, were found to be highly expressed in the undifferentiated hESC lines and down-regulated in differentiated derivatives.

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  • [Cites] J Clin Invest. 2000 Feb;105(3):247-52 [10675349.001]
  • [Cites] Science. 1998 Nov 6;282(5391):1145-7 [9804556.001]
  • [Cites] Stem Cells. 2001;19(3):193-204 [11359944.001]
  • [Cites] Science. 2001 Jul 6;293(5527):95-7 [11441181.001]
  • [Cites] Science. 2001 Aug 10;293(5532):1089-93 [11498579.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2001;2:153-75 [11701647.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10599-604 [12114541.001]
  • [Cites] Annu Rev Cell Dev Biol. 2003;19:237-59 [14570570.001]
  • [Cites] Hum Reprod. 2003 Dec;18(12):2508-11 [14645164.001]
  • [Cites] Stem Cells. 2004;22(3):367-76 [15153613.001]
  • [Cites] Curr Opin Genet Dev. 2004 Apr;14(2):188-95 [15196466.001]
  • [Cites] Annu Rev Genet. 2004;38:553-85 [15568986.001]
  • [Cites] Physiol Rev. 2005 Apr;85(2):635-78 [15788707.001]
  • [Cites] Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R47-58 [15809273.001]
  • [Cites] Nat Genet. 2005 Jun;37(6):585-7 [15864307.001]
  • [Cites] Trends Genet. 2005 Aug;21(8):457-65 [15990197.001]
  • [Cites] Cell Cycle. 2005 Oct;4(10):1323-6 [16205114.001]
  • [Cites] Hum Mol Genet. 2006 Jan 1;15(1):65-75 [16319131.001]
  • [Cites] Nat Biotechnol. 2006 Sep;24(9):1115-22 [16964225.001]
  • [Cites] Nat Biotechnol. 2006 Sep;24(9):1151-61 [16964229.001]
  • [Cites] Stem Cells Dev. 2006 Aug;15(4):532-55 [16978057.001]
  • [Cites] Hum Mol Genet. 2007 Oct 15;16 Spec No. 2:R243-51 [17911167.001]
  • [Cites] Annu Rev Genet. 1997;31:493-525 [9442905.001]
  • [Cites] Nat Biotechnol. 2000 Apr;18(4):399-404 [10748519.001]
  • (PMID = 21607126.001).
  • [ISSN] 1948-0210
  • [Journal-full-title] World journal of stem cells
  • [ISO-abbreviation] World J Stem Cells
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC3097928
  • [Keywords] NOTNLM ; DNA microarray / Human embryonic stem cell / Imprinting / Single nucleotide polymorphism
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99. Riclet R, Chendeb M, Vonesch JL, Koczan D, Thiesen HJ, Losson R, Cammas F: Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation. Mol Biol Cell; 2009 Jan;20(1):296-305
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  • [Title] Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation.
  • Here, we identified the imprinted mesoderm-specific transcript (MEST) gene as an endogenous TIF1beta primary target gene and demonstrated that transcriptional intermediary factor (TIF) 1beta, through its interaction with heterochromatin protein (HP) 1, is essential in establishing and maintaining a local heterochromatin-like structure on MEST promoter region characterized by H3K9 trimethylation and hypoacetylation, H4K20 trimethylation, DNA hypermethylation, and enrichment in HP1 that correlates with preferential association to foci of pericentromeric heterochromatin and transcriptional repression.
  • On disruption of the interaction between TIF1beta and HP1, TIF1beta is released from the promoter region, and there is a switch from DNA hypermethylation and histone H3K9 trimethylation to DNA hypomethylation and histone H3K27 trimethylation correlating with rapid reactivation of MEST expression.
  • Interestingly, we provide evidence that the imprinted MEST allele DNA methylation is insensitive to TIF1beta loss of function, whereas the nonimprinted allele is regulated through a distinct TIF1beta-DNA methylation mechanism.

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  • [Cites] Nucleic Acids Res. 1999 Nov 15;27(22):4324-7 [10536138.001]
  • [Cites] EMBO J. 1999 Nov 15;18(22):6385-95 [10562550.001]
  • [Cites] FEBS Lett. 2000 Apr 28;472(2-3):230-4 [10788617.001]
  • [Cites] Development. 2000 Jul;127(13):2955-63 [10851139.001]
  • [Cites] Mol Cell Biol. 2000 Sep;20(18):6970-83 [10958692.001]
  • [Cites] J Biol Chem. 2000 Dec 22;275(51):40463-70 [11013263.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1422-6 [11171966.001]
  • [Cites] Genes Dev. 2001 Feb 15;15(4):428-43 [11230151.001]
  • [Cites] Genes Dev. 2002 Apr 15;16(8):919-32 [11959841.001]
  • [Cites] J Cell Sci. 2002 Sep 1;115(Pt 17):3439-48 [12154074.001]
  • [Cites] Science. 2003 Jan 31;299(5607):721-5 [12560555.001]
  • [Cites] Bioessays. 2003 Jun;25(6):577-88 [12766947.001]
  • [Cites] Genes Dev. 2003 Aug 1;17(15):1855-69 [12869583.001]
  • [Cites] Mol Cell. 2003 Dec;12(6):1577-89 [14690609.001]
  • [Cites] EMBO J. 2004 Feb 11;23(3):489-99 [14765118.001]
  • [Cites] Mol Cell. 2004 Feb 13;13(3):427-34 [14967149.001]
  • [Cites] Genes Dev. 2004 Jun 1;18(11):1251-62 [15145825.001]
  • [Cites] Genes Dev. 2004 Sep 1;18(17):2147-60 [15342492.001]
  • [Cites] Proc Natl Acad Sci U S A. 1990 Dec;87(24):9923-7 [2124708.001]
  • [Cites] J Cell Biol. 1991 Mar;112(5):965-79 [1847931.001]
  • [Cites] Mol Cell. 1999 Feb;3(2):207-17 [10078203.001]
  • [Cites] Mol Cell Biol. 1999 Jun;19(6):4366-78 [10330177.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3336-41 [15728362.001]
  • [Cites] Dev Dyn. 2005 Mar;232(3):767-74 [15704177.001]
  • [Cites] Mol Cell Biol. 2005 Apr;25(7):2525-38 [15767660.001]
  • [Cites] Mol Cell. 2005 Aug 5;19(3):381-91 [16061184.001]
  • [Cites] EMBO J. 2005 Aug 3;24(15):2783-91 [16001083.001]
  • [Cites] Cancer Res. 2006 Apr 1;66(7):3541-9 [16585178.001]
  • [Cites] Genes Dev. 2006 May 1;20(9):1123-36 [16618801.001]
  • [Cites] Trends Genet. 2006 Jun;22(6):320-9 [16631276.001]
  • [Cites] Genes Dev. 2006 Aug 1;20(15):2041-54 [16882982.001]
  • [Cites] Mol Cell Biol. 2006 Nov;26(22):8623-38 [16954381.001]
  • [Cites] Nat Rev Genet. 2007 Jan;8(1):35-46 [17173056.001]
  • [Cites] Genome Biol. 2006;7(7):228 [17224041.001]
  • [Cites] Nat Genet. 2007 Apr;39(4):457-66 [17334365.001]
  • [Cites] Genes Dev. 2007 May 15;21(10):1169-78 [17470536.001]
  • [Cites] J Biochem. 2007 May;141(5):615-9 [17416595.001]
  • [Cites] Nature. 2007 May 24;447(7143):425-32 [17522676.001]
  • [Cites] Differentiation. 2007 Sep;75(7):627-37 [17381543.001]
  • [Cites] Stem Cells. 2007 Oct;25(10):2498-510 [17600113.001]
  • [Cites] Cell Tissue Res. 2008 Jan;331(1):31-55 [18060563.001]
  • [Cites] Nature. 2008 Mar 6;452(7183):45-50 [18322525.001]
  • [Cites] Nature. 2008 Mar 6;452(7183):112-5 [18322535.001]
  • [Cites] Mol Cell Biol. 2008 May;28(10):3219-35 [18332107.001]
  • [Cites] Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R189-96 [18448610.001]
  • [Cites] Nat Genet. 1995 Sep;11(1):52-9 [7550314.001]
  • [Cites] Genes Dev. 1996 Aug 15;10(16):2067-78 [8769649.001]
  • [Cites] FEBS Lett. 1996 Oct 14;395(1):11-6 [8849680.001]
  • [Cites] EMBO J. 1996 Dec 2;15(23):6701-15 [8978696.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15299-304 [8986806.001]
  • [Cites] Nucleic Acids Res. 1996 Dec 15;24(24):4859-67 [9016654.001]
  • [Cites] J Cell Biol. 1997 Nov 3;139(3):735-47 [9348290.001]
  • [Cites] Hum Mol Genet. 1997 Oct;6(11):1907-15 [9302270.001]
  • (PMID = 18923144.001).
  • [ISSN] 1939-4586
  • [Journal-full-title] Molecular biology of the cell
  • [ISO-abbreviation] Mol. Biol. Cell
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromosomal Proteins, Non-Histone; 0 / Heterochromatin; 0 / Histones; 0 / Nuclear Proteins; 0 / Protein Isoforms; 0 / Proteins; 0 / Transcription Factors; 0 / mesoderm specific transcript protein; 0 / transcriptional intermediary factor 1; 107283-02-3 / heterochromatin-specific nonhistone chromosomal protein HP-1
  • [Other-IDs] NLM/ PMC2613122
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100. Yang Y, Ondrej H, Zhang L, Lu J, Lu M, Wang H, Zheng J, Michal M: Mixed epithelial and stromal tumor of the kidney with cervical and intestinal differentiation. Virchows Arch; 2005 Sep;447(3):669-71
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  • [Title] Mixed epithelial and stromal tumor of the kidney with cervical and intestinal differentiation.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology
  • [MeSH-minor] Cervix Uteri / metabolism. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Intestinal Mucosa / metabolism. Middle Aged. Stromal Cells / metabolism. Stromal Cells / pathology

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  • [Cites] Am J Surg Pathol. 2000 Jul;24(7):958-70 [10895818.001]
  • [Cites] Virchows Arch. 2004 Oct;445(4):359-67 [15322873.001]
  • [Cites] Pathol Res Pract. 1998;194(6):445-8 [9689654.001]
  • (PMID = 16025280.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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