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Items 1 to 76 of about 76
1. Melton JT, Weeden DF: Benign mesenchymoma of the mediastinum: a report and review of the literature. Thorac Surg Sci; 2006;3:Doc02

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mesenchymoma of the mediastinum: a report and review of the literature.
  • Benign mesenchymoma is a rare type of germ cell tumour.
  • An extensive literature search revealed only one described case of mediastinal mesenchymoma in Europe and three cases in Asia.
  • We describe our recent experience of a mediastinal mesenchymoma and present the fascinating imaging and operative findings.

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  • (PMID = 21289950.001).
  • [ISSN] 1862-4006
  • [Journal-full-title] Thoracic surgical science
  • [ISO-abbreviation] Thorac Surg Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC3011340
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2. D'Armiento J, Imai K, Schiltz J, Kolesnekova N, Sternberg D, Benson K, Pardo A, Selman M, Smolarek T, Vundavalli M, Sonnet J, Szabolcs M, Chada K: Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis. Cancer Res; 2007 Mar 1;67(5):1902-9
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis.
  • Previously, HMGA2 was shown to be misexpressed in a number of benign, differentiated mesenchymal tumors including lipomas, uterine leiomyomas, and pulmonary chondroid hamartomas.
  • Therefore, similar to the other mesenchymal neoplasms, HMGA2 misexpression in the smooth muscle cell leads to abnormal proliferation and LAM tumorigenesis.


3. Hwang HS, Lee WJ, Lim HK, Chun HK, Ahn GH: Chondrolipoma in the pelvic cavity: a case report. Korean J Radiol; 2008 Nov-Dec;9(6):563-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A chondrolipoma is an extremely rare form of a benign mesenchymal tumor containing mature cartilage and fatty tissue.
  • [MeSH-major] Chondroma / diagnosis. Lipoma / diagnosis. Mesenchymoma / diagnosis. Pelvic Neoplasms / diagnosis

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  • (PMID = 19039275.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627234
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4. Li J, Omo A, Liu L, Liu L, Tang Y, Pan T: Huge benign mesenchymoma in pharynx-esophagus. Ann Thorac Surg; 2006 Jun;81(6):2283-5
MedlinePlus Health Information. consumer health - Throat Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Huge benign mesenchymoma in pharynx-esophagus.
  • Benign mesenchymoma is an uncommon neoplastic disease and its occurrence in pharynx-esophagus is even more rarely reported.
  • The origin of this tumor was in the pharynx-esophagus, and complete excision was achieved through a laterocervical approach.
  • [MeSH-major] Esophageal Neoplasms / pathology. Mesenchymoma / pathology. Pharyngeal Neoplasms / pathology

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  • (PMID = 16731171.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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5. Chatzidarellis E, Mazaris E, Skolarikos A, Maria D, Mitsogiannis I, Mousiou N, Bisas A: Inflammatory Myofibroblastic Bladder Tumor in a Patient with Von Recklinghausen's Syndrome. Case Rep Med; 2010;2010

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inflammatory Myofibroblastic Bladder Tumor in a Patient with Von Recklinghausen's Syndrome.
  • Myofibroblastic tumor, also known as inflammatory pseudotumor or pseudosarcoma, is a benign tumor with mesenchymal origin.
  • The radiograph evaluation revealed a bladder tumor, and the pathologic examination following a transurethral resection showed inflammatory myofibroblastic tumor of the bladder.
  • The patient finally underwent a radical cystectomy due to the uncertain pathogenesis of inflammatory myofibroblastic tumor as well as the rarity of cases published on bladder tumors in Von Recklinghausen's patients.

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  • (PMID = 20827396.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2935546
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6. Lee HI, Lee JW, Han TY, Li K, Hong CK, Seo SJ, Song KY: A case of dermatofibroma of the upper lip. Ann Dermatol; 2010 Aug;22(3):333-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dermatofibroma (DF) is a common benign mesenchymal tumor composed of fibroblastic and histiocytic cells.

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  • (PMID = 20711274.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2917691
  • [Keywords] NOTNLM ; Dermatofibroma / Lip
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7. Fronie A, Simionescu C, Vască V, Dumitrescu D, Fronie AS: Histopathological aspects of benign mesenchymal tumors located in "high risk areas" of the tongue. Rom J Morphol Embryol; 2010;51(1):97-104

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histopathological aspects of benign mesenchymal tumors located in "high risk areas" of the tongue.
  • Even if they are practically considered to be harmless, benign formations of mesenchymal origin with lingual location represent in the same time a neoplastic lesion under the influence of local and general factors, for a variable period of time.
  • In this study (conducted on a total of 16 cases of benign mesenchymal malignancies), we planned a histopathological evaluation of surgical excision samples obtained from interventions on lingual neoplasias, and harvested from areas with the highest risk for lingual cancer development (pelvilingual groove, the base of the tongue and the insertion of the anterior pillar) in order to assess the histopathological aspects in different types of lesions and the possible presence of degenerative changes.
  • [MeSH-major] Mesenchymoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20191127.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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8. Lazar CC, Liard A, Lechevallier J, Bachy B, Michot C: Secondary localisation of an intra-thoracic benign mesenchymoma in the fossa poplitea: a rare paediatric case. Eur J Pediatr Surg; 2006 Feb;16(1):49-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secondary localisation of an intra-thoracic benign mesenchymoma in the fossa poplitea: a rare paediatric case.
  • Thymomas are tumours that rarely occur in children, are almost invariably benign, and are usually discovered incidentally in the anterior mediastinum on chest X-rays.
  • [MeSH-major] Mediastinal Neoplasms / pathology. Mesenchymoma / secondary. Soft Tissue Neoplasms / secondary. Thymoma / secondary

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  • (PMID = 16544227.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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9. Ito R, Fujiwara M, Takagaki K, Nagasako R: Chondrolipoma of the toe. J Dermatol; 2007 Aug;34(8):570-2
MedlinePlus Health Information. consumer health - Foot Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondrolipoma is a rare benign mesenchymoma composed of mature cartilage and adipose tissue.
  • On histological examination, the tumor contained both mature fat cells and chondrocytes.
  • [MeSH-major] Foot Diseases / diagnosis. Mesenchymoma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 17683390.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / S100 Proteins
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10. Ohtsuka H: Chondrolipoma of the popliteal fossa and Japanese reports. J Dermatol; 2006 Mar;33(3):202-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The presented tumor was an early one because of the shortest duration and the smallest size in Japan.
  • Recent criteria for a benign mesenchymoma including a chondrolipoma were also described.

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  • (PMID = 16620227.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 18
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11. Huang LG, Lu J, Xia SL: [Endoscopic removal of a huge nasal benign mesenchymoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jan;45(1):27
MedlinePlus Health Information. consumer health - Nasal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic removal of a huge nasal benign mesenchymoma].
  • [MeSH-major] Endoscopy. Mesenchymoma / surgery. Nose Neoplasms / surgery

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  • (PMID = 20398534.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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12. Haskell HD, Butt KM, Woo SB: Pleomorphic adenoma with extensive lipometaplasia: report of three cases. Am J Surg Pathol; 2005 Oct;29(10):1389-93
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The differential diagnosis, as it pertains to other fat-containing tumors (such as lipoadenoma, spindle cell lipoma, interstitial lipomatosis, and benign mesenchymoma), is discussed.
  • It is likely that the ability of myoepithelial cells to undergo various metaplasias is the cause of the unusual histologic appearances of this tumor.
  • [MeSH-minor] Adenoma / pathology. Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Lipoma / pathology. Male. Mesenchymoma / pathology. Metaplasia / pathology. Middle Aged

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  • (PMID = 16160483.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Atallah D, Rouzier R, Chamoun ML, Mansour F, Nabaa T, Chababi M, Duvillard P, Chahine G: Benign lipoblastomalike tumor of the vulva: report of a case affecting a young patient. J Reprod Med; 2007 Mar;52(3):223-4
MedlinePlus Health Information. consumer health - Vulvar Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign lipoblastomalike tumor of the vulva: report of a case affecting a young patient.
  • BACKGROUND: Mesenchymal vulvar tumors are rare, and a benign lipoblastomalike tumor may be confused with malignancy.
  • After excision, histologic examination revealed a well-circumscribed and lobulated tumor.
  • CONCLUSION: This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma.
  • Because of the benign behavior of this tumor, complete excision without radiation is recommended.
  • [MeSH-major] Lipoma / pathology. Mesenchymoma / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 17465291.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Hu ZM, Zou SC, Zhao DJ, Zhang CW, Shi D, Ye ZY, Jiang YP: [Diagnosis and treatment of benign duodenal tumor]. Zhonghua Wei Chang Wai Ke Za Zhi; 2005 Jan;8(1):35-7
MedlinePlus Health Information. consumer health - Intestinal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and treatment of benign duodenal tumor].
  • OBJECTIVE: To investigate the diagnosis and treatment of benign duodenal tumor.
  • METHODS: Clinical data of 14 patients with benign duodenal tumor confirmed pathologically or by operation from Oct.1988 to Oct.2001 were analyzed retrospectively.
  • RESULTS: Of 14 patients, 5 had Brunner's grand adenoma, 4 mesenchymoma, 2 leiomyoma, 2 hemangioma, 1 lipoma.
  • Tumor resection was performed in all patients.
  • CONCLUSION: Upper abdominal discomfort and gastrointestinal bleeding are common features in patients with benign duodenal tumor.
  • Surgical tumor resection is the first choice of treatment.

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  • (PMID = 16148996.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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15. Robb A, Rogers T, Nicholls G: A tale of 3 testes? A rare presentation of lipoblastoma with a novel karyotype. J Pediatr Surg; 2010 Jan;45(1):E29-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma is a rare benign mesenchymal tumor of embryonal fat that occurs almost exclusively in infants and children.

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20105570.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Abubakar AM, Mayun AA, Pindiga UH, Chinda JY, Adamu SA: Giant omental lipoma in a 13-year-old adolescent girl. J Pediatr Surg; 2009 Nov;44(11):2230-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although lipoma is a common benign mesenchymal tumor, its occurrence in the omentum is a rare finding.

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  • (PMID = 19944239.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Kim TJ, Lee YS, Song YS, Park CK, Shim SI, Kang CS, Lee KY: Infantile hemangioendothelioma with elevated serum alpha fetoprotein: report of 2 cases with immunohistochemical analysis. Hum Pathol; 2010 May;41(5):763-7
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Infantile hemangioendothelioma is the most common benign mesenchymal tumor of the liver presenting during the first 6 months of life.
  • Serum alpha fetoprotein is an important tumor marker for hepatoblastoma, hepatocellular carcinoma, and germ cell tumors.
  • We report 2 cases of solitary hepatic infantile hemangioendothelioma and demonstrate immunohistochemically that hepatocytes near or entrapped within the tumor were the source of the increased serum levels of alpha fetoprotein explaining the unusual clinical presentation.

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  • [Copyright] Crown Copyright 2010. Published by Elsevier Inc. All rights reserved.
  • [CommentIn] Hum Pathol. 2011 Sep;42(9):1369-71; author reply 1371-2 [21839297.001]
  • (PMID = 20153513.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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18. Moaath A, Raed E, Mohammad R, Mohammad S: Lipoblastoma: a rare mediastinal tumor. Ann Thorac Surg; 2009 Nov;88(5):1695-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipoblastoma: a rare mediastinal tumor.
  • Lipoblastoma is a rare benign mesenchymal tumor of embryonal fat that occurs almost exclusively in infants and children less than age 3.
  • It is a benign tumor with a high recurrence rate.
  • We emphasize that this rare mediastinal tumor should be included in the differential diagnosis of infants having a mediastinal mass.

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  • (PMID = 19853146.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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19. Gómez García I, Molina Burgos R, Fernández Fernández E, Palacio España A, González Chamorro F, Alvarez E, Conde Someso S: [Myofibroblastic tumor of bladder]. Actas Urol Esp; 2005 Jun;29(6):611-4
MedlinePlus Health Information. consumer health - Bladder Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Myofibroblastic tumor of bladder].
  • [Transliterated title] Tumor miofibroblástico de vejiga.
  • The myofibroblastic tumor, is a mesenchymal benign tumor of exceptional character, being its localization but habitual it is the lung; while its appearance in the bladder, is exceptional, not existing but of 100 published cases, of this tumor type in the bladder.
  • This tumor type that clinic and radiologics, behave as a wicked tumor.

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  • (PMID = 16092689.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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20. Ketelsen D, Hartmann J, Horger M: [MR-imaging of aggressive fibromatosis]. Rofo; 2008 Feb;180(2):83-6
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Aggressive fibromatosis is a rare mesenchymal benign tumor characterized histologically by proliferation of fibroblasts and myofibroblasts with marked production of intercellular collagen.

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  • (PMID = 18224580.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 5
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21. Patrozos K, Westphal J, Trawinski J, Wagner W: [Total laparoscopic excision of a leiomyoma of the urinary bladder -- a case report]. Aktuelle Urol; 2005 Feb;36(1):58-60
MedlinePlus Health Information. consumer health - Bladder Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Leiomyoma of the urinary bladder is a rare, benign tumor of mesenchymal origin.

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  • (PMID = 15732006.001).
  • [ISSN] 0001-7868
  • [Journal-full-title] Aktuelle Urologie
  • [ISO-abbreviation] Aktuelle Urol
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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22. Wiedemann A, Jaussi R, Rabs U: [Isolated neurofibromatosis of the urinary bladder. A rare cause of recurrent cystitis]. Urologe A; 2006 Feb;45(2):215-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This benign mesenchymal tumor can be the cause of subvesical obstruction, hematuria or chronic cystitis.

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  • [Cites] Int J Urol. 2001 Nov;8(11):645-7 [11903695.001]
  • [Cites] Eur Urol. 1995;27(3):261-3 [7601195.001]
  • [Cites] Monatsschr Kinderheilkd. 1989 May;137(5):289-92 [2500591.001]
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  • (PMID = 16175398.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


23. Steiner MA, Giles HW: Mesenchymal hamartoma of the liver demonstrating peripheral calcification in a 12-year-old boy. Pediatr Radiol; 2008 Nov;38(11):1232-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenchymal hamartoma of the liver demonstrating peripheral calcification in a 12-year-old boy.
  • Mesenchymal hamartoma of the liver is a rare benign hepatic tumor that typically presents in the first 2 years of life.
  • Although spontaneous regression has been reported in this benign tumor, most mesenchymal hamartomas gradually increase in size and can reach enormous proportions.
  • We present an atypical case of mesenchymal hamartoma in a 12-year-old boy.

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  • [Cites] Radiology. 1986 Mar;158(3):619-24 [3511498.001]
  • [Cites] Comput Med Imaging Graph. 2001 Jan-Feb;25(1):61-5 [11120408.001]
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  • (PMID = 18648751.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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24. Arora R, Abou-Bakr AA, Ahmad MS: Angiomyofibroblastoma of the vulva: report of a rare distinct entity. Gulf J Oncolog; 2010 Jul;(8):35-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyofibroblastoma is a rare benign mesenchymal tumor of lower female genital tract.
  • Clinically it is imperative to differentiate angiomyofibroblastoma from other mesenchymal tumors of this region especially aggressive angiomyxoma which is locally infiltrative and needs long term followup.
  • We stress the need to recognize this tumor on clinicopathologic basis to avoid any potential therapeutic implications.

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  • (PMID = 20601337.001).
  • [ISSN] 2078-2101
  • [Journal-full-title] The Gulf journal of oncology
  • [ISO-abbreviation] Gulf J Oncolog
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Kuwait
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25. Tomita S, Thompson K, Carver T, Vazquez WD: Nodular fasciitis: a sarcomatous impersonator. J Pediatr Surg; 2009 May;44(5):e17-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nodular fasciitis is a benign mesenchymal tumor.

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  • (PMID = 19433154.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromatin
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26. Omori M, Toyoda H, Hirai T, Ogino T, Okada S: Angiomyofibroblastoma of the vulva: a large pedunculated mass formation. Acta Med Okayama; 2006 Aug;60(4):237-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyofibroblastoma is a rare, usually small benign mesenchymal tumor that occurs in vulvar lesions of premenopausal women.
  • The maximum dimension of the tumor measured 11 cm.
  • The resected tumor was well circumscribed with a bulging and glistening cut surface.
  • In the present case, intralesional adipose tissue was present throughout the tumor.
  • There was little stromal mucin throughout the tumor.

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  • (PMID = 16943862.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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27. Chatelain D, Brevet M, Fuks D, Yzet T, Verhaeghe P, Regimbeau JM, Lauwers G, Sevestre H: [Inflammatory fibroid polyp, a rare tumor of the appendix]. Gastroenterol Clin Biol; 2008 Mar;32(3):274-7
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  • [Title] [Inflammatory fibroid polyp, a rare tumor of the appendix].
  • On microscopic examination, the tumor consisted of spindle cells dispersed in a loose fibromyxoid stroma containing numerous blood cells and inflammatory cells with abundant eosinophils.
  • On immunohistochemistry, the spindle tumor cells were positive for vimentin, fascin and focally for CD34 and CD35.
  • Inflammatory fibroid polyp is a rare benign mesenchymal tumor of the gastrointestinal tract rarely reported in the appendix.
  • This tumor shares some common pathologic features with the myofibroblatic inflammatory tumor but they are two different entities.
  • The pathogenesis of this tumor remains unclear but fascin and CD35 immunoreactivity of the tumor cells suggests a probable dendritic cell origin.

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  • (PMID = 18353580.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / CR1 protein, human; 0 / Carrier Proteins; 0 / Microfilament Proteins; 0 / Receptors, Complement 3b; 0 / Vimentin; 146808-54-0 / fascin
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28. Cao D, Srodon M, Montgomery EA, Kurman RJ: Lipomatous variant of angiomyofibroblastoma: report of two cases and review of the literature. Int J Gynecol Pathol; 2005 Apr;24(2):196-200
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  • Angiomyofibroblastoma (AMF) is a rare, benign, mesenchymal tumor occurring mainly in the female genital tract.
  • Immunohistochemical analysis showed that the tumor cells were positive for estrogen receptor, progesterone receptor, vimentin, and Bcl-2, and negative for cytokeratin AE1/1, EMA, and CD117.
  • Tumor cells in the first case were positive for CD34 but not desmin and muscle-specific actin.
  • The opposite expression profile of these three markers was observed in tumor cells in the second case: positive for desmin and muscle-specific actin and negative for CD34.
  • Our findings indicate that the tumor cells in the lipomatous variant have similar immunoprofile to those of usual AMF and support the concept that the lipomatous variant probably represents an extreme end of a wide spectrum of differentiation in AMF.
  • [MeSH-minor] Adipose Tissue / metabolism. Adipose Tissue / pathology. Adult. Biomarkers, Tumor. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Myxoma / pathology

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  • (PMID = 15782077.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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29. Li T, Wang L, Yu HH, Sun HC, Qin LX, Ye QH, Fan J, Tang ZY: Hepatic angiomyolipoma: a retrospective study of 25 cases. Surg Today; 2008;38(6):529-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: We report our experience of diagnosing and treating hepatic angiomyolipoma (HAML), a rare benign mesenchymal tumor.

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  • (PMID = 18516533.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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30. Sohn WI, Kim JH, Jung SN, Kwon H, Cho KJ: Intramuscular lipoma of the sternocleidomastoid muscle. J Craniofac Surg; 2010 Nov;21(6):1976-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intramuscular lipoma is a rare benign mesenchymal tumor that infiltrates the skeletal muscle.
  • In addition, although rare, concerning intramuscular lipoma that developed in the head and neck area, because important structures are present densely in a small space, it is important to establish a preoperative plan by determining the size and location of the tumor through preoperative clinical and radiologic tests.

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  • (PMID = 21119474.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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31. Hatano K, Tsujimoto Y, Ichimaru N, Miyagawa Y, Nonomura N, Okuyama A: Rare case of aggressive angiomyxoma presenting as a retrovesical tumor. Int J Urol; 2006 Jul;13(7):1012-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare case of aggressive angiomyxoma presenting as a retrovesical tumor.
  • Aggressive angiomyxoma (AAM) is a rare mesenchymal benign tumor that preferentially involves the pelvic and perineal regions in relatively young females.
  • We report here a rare case of AAM presenting as a retrovesical tumor in a male patient.
  • A 59-year-old man undergoing abdominal ultrasound examination because of benign prostatic hyperplasia was found to have a retrovesical mass.
  • Computed tomography and magnetic resonance imaging of the pelvis showed the retrovesical tumor to be 7.4 x 6.7 cm.
  • The tumor was resected, and diagnosed histopathologically as AAM.
  • Although the majority of retrovesical tumors are considered to be sarcoma or neurogenic tumor, AAM should also be recognized as a differential diagnosis.

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  • (PMID = 16882078.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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32. Makino E, Yamada J, Tada J, Arata J, Iwatsuki K: Cutaneous angiolipoleiomyoma. J Am Acad Dermatol; 2006 Jan;54(1):167-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The 16-year-old girl had a 2.5- x 1.5-cm subcutaneous tumor on the right buttock, which was slightly tender.
  • The tumor appeared to be vascular and was, therefore, surgically excised.
  • Cutaneous angiomyolipoma, which is also known as cutaneous angiolipoleiomyoma, is a rare benign mesenchymal tumor.

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  • (PMID = 16384779.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Shin JU, Lee KY, Roh MR: A case of a cutaneous angiomyolipoma. Ann Dermatol; 2009 May;21(2):217-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A cutaneous angiomyolipoma, which is also known as a cutaneous angiolipoleiomyoma, is a rare benign mesenchymal tumor.

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  • [Cites] Am J Dermatopathol. 2005 Oct;27(5):418-21 [16148412.001]
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  • (PMID = 20523792.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861200
  • [Keywords] NOTNLM ; Angiolipoleiomyoma / Angiomyolipoma
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34. Garrido Abad P, Coloma del Peso A, Jiménez Gálvez M, Herranz Fernández LM, Arellano Gañán R, Reina Durán T: [Inflammatory myofibroblastic tumor. Case report]. Arch Esp Urol; 2008 Jan-Feb;61(1):62-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Inflammatory myofibroblastic tumor. Case report].
  • [Transliterated title] Tumor miofibroblástico inflamatorio vesical. Aportación de un nuevo caso.
  • OBJECTIVE: To report one case of myofibroblastic bladder tumor.
  • After TUR, inflammatory myofibroblastic tumor of the bladder was diagnosed.
  • CONCLUSION: Myofibroblastic tumor (also known as inflammatory pseudotumor or pseudosarcoma) is a benign tumor with mesenchymal origin.
  • [MeSH-major] Leydig Cell Tumor / pathology. Urinary Bladder Neoplasms / pathology

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  • (PMID = 18405029.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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35. Li T, Fan J, Qin LX, Zhou J, Sun HC, Wang L, Ye QH, Qiu SJ, Tang ZY: [A clinicopathologic study of hepatic angiomyolipoma]. Zhonghua Wai Ke Za Zhi; 2009 Oct 15;47(20):1536-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSIONS: HAML is a rare benign mesenchymal tumor of the liver.

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  • (PMID = 20092740.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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36. Castaño JC, Vélez A, Raül Flórez F, Uribe CA: [Renal lymphangioma]. Arch Esp Urol; 2005 Apr;58(3):256-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSIONS: Renal lymphangioma is a mesenchymal tumor of benign behavior which poses several diagnostic difficulties, both radiologically and histologically.
  • This tumor may be confused with other renal tumors, including clear cell renal carcinoma.

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  • (PMID = 15906622.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 5
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37. Leinung S, Möbius C, Udelnow A, Hauss J, Würl P: Histopathological outcome of 597 isolated soft tissue tumors suspected of soft tissue sarcoma: a single-center 12-year experience. Eur J Surg Oncol; 2007 May;33(4):508-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Open biopsy revealed soft tissue sarcoma in 318 cases, benign mesenchymal tumor in 124 cases and isolated metastases (ISTM) from carcinomas in 98 patients; other pathologies were found in 57 patients.
  • CONCLUSIONS: In our collective with soft tissue tumor, 50% of the patients had the diagnosis of soft tissue sarcoma, 20% presented with a metastasis of carcinoma and 20% had a benign tumor.

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  • (PMID = 17081724.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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38. Srinivasan VD, Wayne JD, Rao MS, Zynger DL: Solitary fibrous tumor of the pancreas: case report with cytologic and surgical pathology correlation and review of the literature. JOP; 2008;9(4):526-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the pancreas: case report with cytologic and surgical pathology correlation and review of the literature.
  • CONTEXT: Solitary fibrous tumor is an uncommon spindle cell tumor which can occur in a variety of locations.
  • Four cases of pancreatic solitary fibrous tumor have been reported in the literature.
  • CASE REPORT: We report the fifth case of pancreatic solitary fibrous tumor in a 78-year-old woman who presented with back pain and weight loss.
  • Imaging studies were suggestive of an endocrine tumor.
  • Endoscopic ultrasound with fine needle aspiration was performed and revealed a benign mesenchymal tumor, which is the first successful report of cytology on a pancreatic solitary fibrous tumor.
  • The patient underwent a distal pancreatectomy with resection of the mass which was diagnosed as solitary fibrous tumor, supported by immunohistochemical studies showing positivity for CD99, vimentin, bcl-2, and CD34.
  • CONCLUSION: Diagnosing pancreatic solitary fibrous tumor is challenging due to its rarity, nonspecific clinical presentation, and difficulty to be radiologically distinguished from other pancreatic lesions.

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  • (PMID = 18648147.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 7
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39. Andreu García A, Herrero Polo E, Alapont Alacreu JM, Coronel Sánchez MB, Schiefenbuch Munné E, Botella Almodovar R, Brotons Márquez JL, Llamazares Cachá G: [Renal leiomyoma: case report]. Arch Esp Urol; 2006 Jan-Feb;59(1):81-4
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  • CONCLUSIONS: Renal leiomyoma is a rare benign mesenchymal tumor that should be taken into consideration for the differential diagnosis of renal masses, because it would be an indication for nephron-sparing surgery; nevertheless, due to the difficulties to differentiate it from renal cell carcinoma it is not rare that the diagnosis is achieved after histological study of the nephrectomy specimen.

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  • (PMID = 16568699.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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40. Goldman A, Wollina U: Lipoma treatment with a subdermal Nd:YAG laser technique. Int J Dermatol; 2009 Nov;48(11):1228-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Lipoma is the most common benign mesenchymal tumor composed of mature fat cells.
  • RESULTS: Subdermal lipoma treatment using a 1064-nm Nd:YAG laser resulted in complete or almost complete removal of the tumor in 100% of patients.

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  • (PMID = 20064183.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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41. Quicios Dorado C, Allona Almagro A: [Renal angiomyolipoma causing inferior vena cava thrombus and secondary Budd-Chiari's syndrome]. Arch Esp Urol; 2008 Apr;61(3):435-9
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  • OBJECTIVE: We report one case of renal angiomyolipoma with three characteristics: renal sinus origin, inferior vena cava tumor thrombus reaching the right atrium and Budd-Chiari syndrome.
  • RESULTS/CONCLUSIONS: Renal angiomyolipoma is a benign mesenchymal tumor.
  • It is an uncommon tumor (2-6.4% of all kidney tumors), with a female predominance.
  • They can involve the renal vein, the inferior vena cava and even the right atrium as a tumor thrombus.
  • Angiomyolipoma commonly present as an incidental finding on radiographic studies, but the clinical presentation varies from flank pain to fatal pulmonary tumor embolism.
  • Because of the risk of potentially fatal cardiopulmonary embolism and death, surgical treatment (radical nephrectomy plus tumor thrombectomy) of these lesions is indicated even when they are asymptomatic.

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  • (PMID = 18581683.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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42. van Boekel G, Ruinemans-Koerts J, Joosten F, Dijkhuizen P, van Sorge A, de Boer H: Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling. Eur J Endocrinol; 2008 Mar;158(3):431-7
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  • [Title] Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling.
  • BACKGROUND: Tumor-induced osteomalacia is a rare paraneoplastic syndrome characterized by hypophosphatemia, renal phosphate wasting, suppressed 1,25-dihydroxyvitamin D production, and osteomalacia.
  • It is caused by a usually benign mesenchymal tumor producing fibroblast growth factor 23 (FGF-23).
  • Surgical excision of the tumor is the first choice of treatment because complete resection is curative.
  • CASE: In this report, we describe the diagnostic value of two-staged venous sampling to localize the FGF-23 secreting tumor in a case where conventional imaging failed.
  • In addition, we examined the effect of dipyridamole on renal phosphate excretion, explored the efficacy of octreotide and calcitonin to suppress the FGF-23 production, and closely evaluated the hormonal changes following successful removal of the tumor.
  • The latter observations indicate that calcitonin may be useful to suppress tumor-FGF-23 production and that FGF-23 may be a clinically relevant inhibitor of parathyroid hormone secretion in man.

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  • (PMID = 18299479.001).
  • [ISSN] 1479-683X
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / fibroblast growth factor 23; 62031-54-3 / Fibroblast Growth Factors
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43. Ma L, Kowalski D, Javed K, Hui P: Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: a case report with p53 gene mutation analysis. Arch Pathol Lab Med; 2005 May;129(5):676-9
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  • Angiomyolipoma (AML) is the most common benign mesenchymal tumor of the kidney.
  • The tumor consisted of mostly epithelioid cells with marked nuclear pleomorphism and frequent mitoses and was positive for HMB-45.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cytoplasm / ultrastructure. DNA Mutational Analysis. DNA, Neoplasm / genetics. Female. Humans. Immunohistochemistry. Intercellular Junctions / ultrastructure. Nephrectomy. Polymerase Chain Reaction. Polymorphism, Single-Stranded Conformational. Treatment Outcome

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  • (PMID = 15859641.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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44. Carretto E, Dall'Igna P, Alaggio R, Siracusa F, Granata C, Ferrari A, Cecchetto G: Fibrous hamartoma of infancy: an Italian multi-institutional experience. J Am Acad Dermatol; 2006 May;54(5):800-3
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  • BACKGROUND: Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass.

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  • (PMID = 16635660.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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45. Pudil J, Martínek J, Belsan T, Ryska M: [Atypically localised hepatic haemangioma as a cause of dyspeptic syndrome]. Rozhl Chir; 2006 Jul;85(7):354-6
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  • INTRODUCTION: Haemangioma is a benign mesenchymal tumor growing from the endothehum of blood vessels.
  • USG, CT, MR, CT angiography and EUS have all shown two lesiones (haemangioma of the left hepatic lobe, a tumor in the left subphrenic area of uncertain origin).

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  • (PMID = 17044281.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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46. Agaimy A, Bihl MP, Tornillo L, Wünsch PH, Hartmann A, Michal M: Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis. Am J Surg Pathol; 2010 Feb;34(2):271-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis.
  • Calcifying fibrous tumor (CFT) is a rare benign mesenchymal tumor composed of hyalinized fibrous tissue with interspersed bland fibroblastic spindled cells, scattered psammomatous, and/or dystrophic calcifications and variably prominent mononuclear inflammatory infiltrate.
  • Mean tumor size was 2.2 cm.
  • One ulcerated tumor caused iron deficiency anemia and ulcer symptoms.
  • In none of the cases were there remnants of burnt-out GIST, inflammatory fibroid polyp, inflammatory myofibroblastic tumor, leiomyoma, schwannoma, or other specific lesion.
  • Gastric CFTs are distinct from sclerosing GIST and other mesenchymal gut lesions and may represent a localized inflammatory fibrosclerosis in response to immune-mediated or other-type tissue injury affecting the muscularis propria.
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. DNA Mutational Analysis. Female. Humans. Incidental Findings. Male. Middle Aged

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  • (PMID = 20090503.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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47. Ducarme G, Valentin M, Davitian C, Felce-Dachez M, Luton D: Angiomyofibroblastoma: a rare vulvar tumor. Arch Gynecol Obstet; 2010 Jan;281(1):161-2
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  • [Title] Angiomyofibroblastoma: a rare vulvar tumor.
  • INTRODUCTION: Angiomyofibroblastoma is a rare, benign mesenchymal tumor that occurs mainly in the vulval region of middle age (35-45 years) women.

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  • (PMID = 19430941.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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48. Hox V, Vander Poorten V, Delaere PR, Hermans R, Debiec-Rychter M, Sciot R: Extramammary myofibroblastoma in the head and neck region. Head Neck; 2009 Sep;31(9):1240-4
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  • BACKGROUND: Mammary myofibroblastoma is a benign mesenchymal tumor of the breast.
  • CONCLUSION: We describe this case because of the unusual location of this rare tumor.

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  • (PMID = 19132718.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Guevara N, Lassalle S, Castillo L, Butori C, Santini J: [Angiomyolipoma of the parotid gland]. Ann Otolaryngol Chir Cervicofac; 2008 Apr;125(2):90-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Angiomyolipoma is a rare benign mesenchymal tumor.
  • Partial parotidectomy was performed and the tumor showed the characteristic appearance of angiomyolipoma, with an admixture of fat smooth cells and tortuous thick-walled blood vessels.
  • CONCLUSION: This article discusses the presentation and management associated with this exceptional tumor.

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  • (PMID = 18280455.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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50. Brunschweiler B, Guedj N, Lenoir T, Faillot T, Rillardon L, Guigui P: Oncogenous osteomalacia and myopericytoma of the thoracic spine: a case report. Spine (Phila Pa 1976); 2009 Nov 1;34(23):E857-60
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  • SUMMARY OF BACKGROUND DATA: Osteomalacia related to a tumor is well known.
  • The cause of the disorder is usually a highly vascularized, benign tumor of mesenchymal origin.
  • Location of the tumor in the spine is very rare.
  • Removal of the tumor is followed by resolution of osteomalacia.
  • Localization of the tumor at T5 and T6 levels was obtained by magnetic resonance imaging.
  • Surgical treatment consisted in a circumferential correction-fusion with hemivertebrectomy of T5 and T6 and tumor removal.
  • RESULTS: Tumor removal was rapidly followed by disappearance of the clinical symptoms of osteomalacia, and by correction of hypophosphatemia.
  • At 2-years follow-up, no recurrence of the tumor was detectable on imaging studies-the correction fusion remained stable.
  • Histologically, the tumor was classified as a myopericytoma.
  • However, secondary recurrence of the biologic markers due to an incomplete tumor removal was disclosed.
  • CONCLUSION: Removal of the tumor was followed by healing of the clinical features of osteomalacia, demonstrating the causal connection between the myopericytoma and the osteopathy.
  • [MeSH-minor] Adult. Biomarkers, Tumor. Female. Follow-Up Studies. Humans. Spine / pathology. Spine / surgery. Treatment Outcome

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  • (PMID = 19927092.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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51. Yu K, Liu Y, Wang H, Hu S, Long C: Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases. Interact Cardiovasc Thorac Surg; 2007 Oct;6(5):636-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of primary cardiac tumors, the incidence of benign neoplasm was much higher than malignant masses (90.6% vs. 9.4%, P<0.01).
  • The most common benign cardiac tumor was myxoma (86.8%).
  • Mesenchymoma and angiosarcoma were the most common primary malignant cardiac tumors.
  • Benign non-myxoma tumors are more likely to occur in the ventricular (64.3%).
  • [MeSH-major] Asian Continental Ancestry Group / statistics & numerical data. Heart Neoplasms. Hemangiosarcoma. Lipoma. Mesenchymoma. Myxoma. Rhabdomyoma

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  • (PMID = 17670730.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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52. Rau TT, Hartmann A, Dietmaier W, Schmitz J, Hohenberger W, Hofstaedter F, Katenkamp K: Plexiform angiomyxoid myofibroblastic tumour: differential diagnosis of gastrointestinal stromal tumour in the stomach. J Clin Pathol; 2008 Oct;61(10):1136-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mesenchymal tumours other than gastrointestinal stromal tumours are rare in the stomach.
  • Plexiform angiomyxoid myofibroblastic tumour is a recently described new entity of a presumably benign mesenchymal gastric tumour.
  • Plexiform angiomyxoid myofibroblastic tumour may present a new mesenchymal tumour entity in the stomach.
  • [MeSH-major] Gastrointestinal Stromal Tumors / pathology. Mesenchymoma / pathology. Stomach Neoplasms / pathology

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  • (PMID = 18820104.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 7
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53. Machaladze ZO, Davydov MI, Polotskiĭ BE, Karseladze AI, Savelov NA: [Surgery for mesenchymal tumours of the mediastinum]. Khirurgiia (Mosk); 2008;(4):43-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgery for mesenchymal tumours of the mediastinum].
  • Results of treatment of 52 patients with mesenchymal tumours of the mediastinum.
  • Among 52 patients with mesenchymal tumours of the mediastinum, 40 patients were treated surgically and 12 patients got conservative treatment.
  • Radical surgical treatment was carried out in 21 patients with benign tumors.
  • Benign tumors have a favorable prognosis after surgical treatment.
  • Major factors of the prognosis of surgical treatment are dissemination and the histologic form of a tumor as well as type of surgical intervention.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Mediastinoscopy / methods. Mesenchymoma / surgery. Thoracic Surgery, Video-Assisted / methods

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  • (PMID = 18454108.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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54. Bezerra MF, Costa FW, Pereira KM, Cavalcante RB, Pouchain EC: Chondrolipoma of the posterior tongue. J Craniofac Surg; 2010 Nov;21(6):1982-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondrolipomas are rare benign mesenchymal tumors characterized by the proliferation of mature adipocytes associated with variable amounts of mature cartilaginous tissue.
  • [MeSH-major] Mesenchymoma / diagnosis. Tongue Neoplasms / diagnosis

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  • (PMID = 21119476.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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55. Rajaram V, Knezevich S, Bove KE, Perry A, Pfeifer JD: DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation. Genes Chromosomes Cancer; 2007 May;46(5):508-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation.
  • Undifferentiated embryonal sarcoma of the liver is a highly malignant and aggressive tumor that occasionally arises within mesenchymal hamartoma of the liver (MHL), a benign tumor that typically occurs in young children.
  • The breakpoint at 19q13.4 occurs at a locus we refer to as MHLB1, for Mesenchymal Hamartoma of the Liver Breakpoint 1.
  • [MeSH-minor] Base Sequence. Chromosome Mapping. Chromosomes, Artificial, Bacterial. DNA Primers. Humans. In Situ Hybridization, Fluorescence. Mesenchymoma / genetics. Molecular Sequence Data. Polymerase Chain Reaction

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17311249.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Neoplasm
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56. Eisner BH, McAleer SJ, Gargollo PC, Perez-Atayde A, Diamond DA, Elder JS: Pediatric penile tumors of mesenchymal origin. Urology; 2006 Dec;68(6):1327-30

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  • [Title] Pediatric penile tumors of mesenchymal origin.
  • OBJECTIVES: To describe 2 cases of mesenchymal pediatric penile tumors in a 13-year-old boy and an 11-month-old infant.
  • Mesenchymal tumors are rare in the male external genitalia.
  • Because of malignancy, the first patient underwent wide reexcision of the tumor site.
  • RESULTS: The pathologic findings of the first case were combined dermatofibrosarcoma protuberans, giant cell fibroblastoma, and fibrosarcoma, a malignant tumor.
  • Immunohistochemical staining showed strong and diffuse CD34 cytoplasmic positivity in the giant cell fibroblastoma and dermatofibrosarcoma protuberans components; the dedifferentiated fibrosarcoma tumor cells were negative for this antibody.
  • The second case was myofibroma, a benign fibroblastic tumor with a prominent myofibroblastic component that is congenital and tends to occur within the first few months after birth.
  • [MeSH-major] Mesenchymoma. Penile Neoplasms

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  • (PMID = 17169655.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Ahrens WA, Ridenour RV 3rd, Caron BL, Miller DV, Folpe AL: GLUT-1 expression in mesenchymal tumors: an immunohistochemical study of 247 soft tissue and bone neoplasms. Hum Pathol; 2008 Oct;39(10):1519-26
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  • [Title] GLUT-1 expression in mesenchymal tumors: an immunohistochemical study of 247 soft tissue and bone neoplasms.
  • However, GLUT-1 expression has not been systematically examined in other mesenchymal neoplasms.
  • Prompted by a recent report of GLUT-1 expression in epithelioid sarcoma, a tumor not generally felt to show perineurial differentiation, we examined GLUT-1 expression in a wide variety of mesenchymal tumors.
  • Sections from 247 mesenchymal tumors of a variety of histologic subtypes were retrieved from our archives and immunostained for GLUT-1 using heat-induced epitope retrieval and the DAKO ADVANCE detection system (DAKO, Carpinteria, CA).
  • All benign nerve sheath tumors showed a peripheral rim of positive normal perineurial cells, with 2 neurofibromas and 3 schwannomas showing more extensive staining.
  • GLUT-1 expression was also seen in a wide variety of benign and malignant mesenchymal tumors.
  • We conclude that GLUT-1 expression in mesenchymal tumors is by no means specific for perineurial differentiation, but may instead represent upregulation of this protein within hypoxic zones, secondary to upstream activation of proteins such as hypoxia-inducible factor 1-alpha.
  • [MeSH-major] Bone Neoplasms / metabolism. Glucose Transporter Type 1 / metabolism. Mesenchymoma / metabolism. Soft Tissue Neoplasms / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cell Count. Humans. Immunohistochemistry. Neoplasm Proteins / metabolism

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  • (PMID = 18620729.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glucose Transporter Type 1; 0 / Neoplasm Proteins
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58. Cheng B, Zhong L, Ding F, Xie HP, Wang Y, Yang YZ, Liu M, Wan J: [A comparative study of the diagnostic value of endoscopic ultrasonography with pathological features of upper gastrointestinal mesenchymal tumors]. Zhonghua Nei Ke Za Zhi; 2009 Sep;48(9):724-8

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  • [Title] [A comparative study of the diagnostic value of endoscopic ultrasonography with pathological features of upper gastrointestinal mesenchymal tumors].
  • OBJECTIVE: To study the pathological and immunohistochemical features of upper gastrointestinal mesenchymal tumors (GIMTs) and compare them with endoscopic ultrasonographic (EUS) characteristics so as to evaluate the diagnostic value of EUS in upper digestive tract GIMTs.
  • RESULTS: In the 72 cases of upper digestive tract GIMTs, 37 cases were diagnosed as stromal tumor with pathological and immunohistochemical methods (51.4%); 21 of them were malignant, accounting for 56.7% of the stromal tumors.
  • EUS showed that 38 cases were originated from the muscularis mucosae layer; 33 of them were leiomyoma and 5 stromal tumor.
  • Thirty-two cases were gastric GIMTs, EUS showed that 2 cases originating from the muscularis mucosae layer were gastric stromal tumor.
  • Of the 30 cases originating from the muscularis propria layer, 28 cases were stromal tumor, 1 case was leiomyoma and 1 case was schwannoma.
  • The sensitivity and the specificity of EUS in distinguishing benign and malignant stromal tumors according to sonographic characteristics were 81.0% and 93.8% respectively.
  • CONCLUSION: Stromal tumor is more common in stomach mesenchymal neoplasms and is more often originated from the muscularis propria layer in EUS; leiomyoma is more common in esophagus and is more often originated from the muscularis mucosae layer.
  • The diagnostic sensitivity and specificity of EUS are high in distinguishing benign and malignant character of upper digestive tract GIMTs.
  • [MeSH-major] Gastrointestinal Neoplasms / pathology. Gastrointestinal Neoplasms / ultrasonography. Mesenchymoma / pathology. Mesenchymoma / ultrasonography

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  • (PMID = 20079206.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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59. Mathur SR, Gupta R, Seith A, Agarwala S, Subramanian S, Gupta SD: Aspiration cytology of mesenchymal hamartoma of the chest wall in an infant: a case report. Acta Cytol; 2010 Jan-Feb;54(1):63-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aspiration cytology of mesenchymal hamartoma of the chest wall in an infant: a case report.
  • BACKGROUND: Mesenchymal hamartoma of the chest wall is an extremely uncommon lesion of infants.
  • Radiologic features simulate a malignant neoplasm; however, pathologic examination demonstrates an admixture of fibroblasts, benign cartilage and woven bone.
  • A cytologic diagnosis of a benign chondroid, possibly hamartomatous lesion was given, which was confirmed as mesenchymal hamartoma on histopathologic examination.
  • CONCLUSION: Mesenchymal hamartoma is a rare chest wall lesion that can be diagnosed on cytology, provided that the cytopathologist is aware of this uncommon entity and appreciates the benign cytologic features.
  • [MeSH-major] Hamartoma / pathology. Mesenchymoma / pathology. Thoracic Wall

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  • (PMID = 20306991.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Peterson NR, Summerlin DJ, Cordes SR: Multiple phosphaturic mesenchymal tumors associated with oncogenic osteomalacia: case report and review of the literature. Ear Nose Throat J; 2010 Jun;89(6):E11-5
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  • [Title] Multiple phosphaturic mesenchymal tumors associated with oncogenic osteomalacia: case report and review of the literature.
  • Oncogenic osteomalacia is a rare paraneoplastic syndrome that occurs secondary to tumor development in a variety of locations.
  • The most common causal tumor is phosphaturic mesenchymal tumor (PMT), a histologically benign lesion.
  • Despite resection of both tumors, the patient's signs and symptoms did not resolve, suggesting either incomplete tumor removal or the presence of another undetected tumor.
  • [MeSH-major] Bone Neoplasms / etiology. Hypophosphatemia, Familial / pathology. Mesenchymoma / etiology. Osteomalacia / complications. Tibia / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Neoplasms, Connective and Soft Tissue / pathology

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  • (PMID = 20556724.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 36
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61. Zimering MB, Caldarella FA, White KE, Econs MJ: Persistent tumor-induced osteomalacia confirmed by elevated postoperative levels of serum fibroblast growth factor-23 and 5-year follow-up of bone density changes. Endocr Pract; 2005 Mar-Apr;11(2):108-14
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  • [Title] Persistent tumor-induced osteomalacia confirmed by elevated postoperative levels of serum fibroblast growth factor-23 and 5-year follow-up of bone density changes.
  • OBJECTIVE: To describe a case of persistent tumor-induced osteomalacia, determine whether serum fibroblast growth factor-23 (FGF-23) levels postoperatively indicate incomplete tumor resection, and report lumbar spine and forearm bone mineral density (BMD) changes during 5 years of follow-up.
  • RESULTS: A 52-year-old man, who presented with muscle weakness and multiple fractures, was found to have low values for serum phosphorus, serum 1,25-dihydroxyvitamin D, and maximal tubular reabsorption of phosphate per glomerular filtration rate, a high level of serum alkaline phosphatase, and a normal serum concentration of parathyroid hormone, characteristic of tumor-induced osteomalacia.
  • Magnetic resonance imaging to evaluate an abnormality of the left foot revealed a soft tissue mass, biopsy of which confirmed the presence of a benign, phosphaturic, mesenchymal tumor.
  • The baseline serum FGF-23 level (2,050 RU/mL) was more than 17 times the upper limit of normal for adults (23 to 118 RU/mL) and decreased substantially within 1 day after partial resection of the tumor but remained above normal postoperatively.
  • CONCLUSION: The serum FGF-23 level is high in a substantial proportion of patients with tumor-induced osteomalacia.
  • The postoperative above normal levels of serum FGF-23 correlated with known persistence of tumor in our study patient.
  • This result suggests that this assay can provide clinicians with rapid prognostic information in patients with known or suspected residual tumor.
  • BMD should be assessed at both appendicular and axial sites in patients with persistent tumor-induced osteomalacia.
  • [MeSH-major] Bone Density. Fibroblast Growth Factors / blood. Foot. Mesenchymoma / complications. Osteomalacia / etiology. Soft Tissue Neoplasms / complications

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  • (PMID = 15901526.001).
  • [ISSN] 1530-891X
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / fibroblast growth factor 23; 62031-54-3 / Fibroblast Growth Factors
  • [Number-of-references] 18
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62. Vujanić GM, Kelsey A, Perlman EJ, Sandstedt B, Beckwith JB: Anaplastic sarcoma of the kidney: a clinicopathologic study of 20 cases of a new entity with polyphenotypic features. Am J Surg Pathol; 2007 Oct;31(10):1459-68
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  • The tumors were identified by re-reviewing tumors with unusual anaplastic features from the National Wilms Tumor Study Pathology Center, the International Society of Pediatric Oncology and the United Kingdom Children's Cancer Study Group trials.
  • The nodules of cartilage showed both benign and malignant features, often within the same tumor.
  • Cytokeratin, using the antibody CAM5.2, was uniformly negative within the tumor cells.
  • Tumor stage was known in 15 patients including 7 stage I, 4 stage II, 3 stage III, and 1 stage IV tumors.
  • One patient with stage I tumor developed widespread metastases and died.
  • Five stage I patients were alive and free of tumor at last follow-up.
  • In the differential diagnosis, anaplastic Wilms tumor, primary renal synovial sarcoma, malignant mesenchymoma, ectomesenchymoma, and mesenchymal chondrosarcomas have been considered but none of these tumors shared the same features as the 20 cases described here which represent a distinct clinicopathologic entity with morphologic features of a polyphenotypic anaplastic sarcoma of the kidney.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Child. Child, Preschool. Desmin / analysis. Disease-Free Survival. Female. Gene Expression. Humans. Immunoenzyme Techniques. Infant. Male. Neoplasm Recurrence, Local. Neoplasm Staging. Nephrectomy. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. Phenotype. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Vimentin / analysis

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  • (PMID = 17895746.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Oncogene Proteins, Fusion; 0 / RNA, Messenger; 0 / SYT-SSX fusion protein; 0 / Vimentin
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63. Yoshioka K, Nagata R, Ueda M, Yamaguchi T, Konishi Y, Hosoi M, Inoue T, Yamanaka K, Iwai Y, Sato T: Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy. Intern Med; 2006;45(20):1157-60
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  • [Title] Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy.
  • He had undergone surgery 2 years previously for a "benign unclassified mesenchymal tumor" in the skull, but there were no clinical symptoms related to osteomalacia.
  • The diagnosis of tumor-induced osteomalacia due to phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) was made by re-examining the pathologic specimens.
  • [MeSH-major] Cranial Fossa, Posterior / pathology. Hypophosphatemia, Familial / etiology. Mesenchymoma / complications. Osteomalacia / etiology. Skull Base Neoplasms / complications

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  • (PMID = 17106161.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Phosphates; 1406-16-2 / Vitamin D; 66772-14-3 / 1,25-dihydroxyvitamin D; RWM8CCW8GP / Octreotide
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64. Zhu X, Zhang XQ, Li BM, Xu P, Zhang KH, Chen J: Esophageal mesenchymal tumors: endoscopy, pathology and immunohistochemistry. World J Gastroenterol; 2007 Feb 7;13(5):768-73
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  • [Title] Esophageal mesenchymal tumors: endoscopy, pathology and immunohistochemistry.
  • AIM: To study the endoscopic, pathological and immunohistochemical features of esophageal mesenchymal tumors.
  • METHODS: Twenty-nine patients diagnosed as esophageal mesenchymal tumors by electronic endoscopy and endoscopic ultrasound (EUS) were observed under light microscopes, and all tissues were stained by the immunohistochemical method.
  • CONCLUSION: The most common esophageal mesenchymal tumors are leiomyomas, and esophageal GISTs are less common.
  • Most of esophageal LMs and GISTs are benign.
  • Endoscopy and EUS are the effective methods to diagnose esophageal mesenchymal tumors and they can provide useful information for the treatment of these tumors.
  • [MeSH-major] Endoscopy, Gastrointestinal. Esophageal Neoplasms / pathology. Leiomyoma / pathology. Mesenchymoma / pathology

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  • (PMID = 17278201.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Other-IDs] NLM/ PMC4066011
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65. Joyner DE, Wade ML, Szabo A, Bastar J, Coffin CM, Albritton KH, Bernard PS, Randall RL: Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo. J Cancer Res Clin Oncol; 2005 Mar;131(3):137-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo.
  • BACKGROUND: Mesenchymal neoplasia comprises a heterogeneous group of tumors with over 200 benign neoplasms and 100 sarcomas.
  • As a feasibility study, our goal was to generate a preliminary discriminatory gene list for selected mesenchymal tumors, including sarcomas.
  • This technique may enable an eventual molecular classification schema based on expression profiles that can complement current clinical and pathologic diagnostic procedures in mesenchymal tumors.
  • Messenger RNA (mRNA) from four general tumor classes was competitively hybridized against a human dermal fibroblast cell line comparator and the resulting gene expression profiles processed by ANOVA and linear discriminate analysis.
  • RESULTS: The tissue classification involved 18 patients with malignant peripheral nerve sheath tumors, giant cell containing tumors, benign spindle cell lesions, or Ewing's family of tumors.
  • CONCLUSIONS: Linear discriminate analysis of cDNA gene expression profiles partitioned mesenchymal tumor classes, even when constrained by limited sample sizes.
  • [MeSH-major] DNA Fingerprinting. DNA, Neoplasm / analysis. Mesenchymoma / diagnosis. Mesenchymoma / genetics. Neoplasms, Connective Tissue / diagnosis. Neoplasms, Connective Tissue / genetics. Oligonucleotide Array Sequence Analysis

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  • (PMID = 15614524.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / RNA, Messenger; 0 / RNA, Neoplasm
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66. Pawel BR, Crombleholme TM: Mesenchymal hamartoma of the chest wall. Pediatr Surg Int; 2006 Apr;22(4):398-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenchymal hamartoma of the chest wall.
  • Mesenchymal hamartoma of the chest wall is an unusual lesion remarkable for its occurrence in early infancy and alarming clinical presentation, which often suggests malignancy.
  • Despite its aggressive appearance and propensity to attain massive size, the lesion behaves biologically in a benign fashion, and may be treated conservatively, provided that there is no respiratory compromise secondary to mass effect.
  • The case of an incompletely resected mesenchymal hamartoma that has behaved in a benign fashion after more than 4 years of follow-up is discussed here.
  • We present this case to provide insight and raise clinicians' awareness of the behavior of an extremely rare tumor.
  • [MeSH-major] Hamartoma / diagnosis. Mesenchymoma / diagnosis. Thoracic Wall / diagnostic imaging

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  • (PMID = 16331523.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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67. Vardar E, Gunlusoy B, Arslan M, Kececi S: Myointimoma of the glans penis. Pathol Int; 2007 Mar;57(3):158-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myointimoma is a recently described benign tumor, which is regarded as a rare type of mesenchymal tumor of the penis.
  • The histological findings revealed a multinodular tumor that was characterized by spindle-shaped cells located in the intravascular area.
  • [MeSH-major] Mesenchymoma / pathology. Penile Neoplasms / pathology. Penis / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunoenzyme Techniques. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17295649.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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68. Seckin D, Demirkesen C, Gurbuz O: Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue. J Am Acad Dermatol; 2008 Aug;59(2 Suppl 1):S23-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue.
  • Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue is a benign rare tumor.
  • Histopathologically, the tumor is composed of a well-circumscribed, lobular proliferation of fusiform and ovoid cells in a chondromyxoid background.
  • Histogenetic origin of the tumor is uncertain.
  • Total excision was performed and histopathologic findings were consistent with ectomesenchymal chondromyxoid tumor.
  • [MeSH-major] Mesenchymoma / pathology. Tongue / pathology. Tongue Neoplasms / pathology

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  • (PMID = 18625372.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Williams K, Flanagan A, Folpe A, Thakker R, Athanasou NA: Lymphatic vessels are present in phosphaturic mesenchymal tumours. Virchows Arch; 2007 Nov;451(5):871-5
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  • [Title] Lymphatic vessels are present in phosphaturic mesenchymal tumours.
  • Oncogenic osteomalacia (OO) is an acquired form of hypophosphataemic osteomalacia, which is associated most commonly with the development of a benign phosphaturic mesenchymal tumour mixed connective tissue type (PMTMCT).
  • Taken with previous observations that PMTMCTs overexpress FGF23 and other gene products, this finding provides further evidence that most osteomalacia associated mesenchymal tumours represent a discrete pathological entity.
  • [MeSH-major] Bone Neoplasms / pathology. Lymphatic Vessels / pathology. Mesenchymoma / pathology. Osteomalacia / pathology

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  • [Cites] Cancer. 1987 Apr 15;59(8):1442-54 [3545439.001]
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  • (PMID = 17674036.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / Phosphates; 0 / fibroblast growth factor 23; 62031-54-3 / Fibroblast Growth Factors
  • [Number-of-references] 23
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70. Zhong DR, Liu TH, Yang D, Feng RE, Cui QC, Luo YF, Jia Y: [Clinicopathologic study of 10 cases of osteomalacia or rickets-associated mesenchymal tumors]. Zhonghua Bing Li Xue Za Zhi; 2005 Nov;34(11):724-8
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  • [Title] [Clinicopathologic study of 10 cases of osteomalacia or rickets-associated mesenchymal tumors].
  • OBJECTIVE: To study the clinicopathologic features of osteomalacia or rickets-associated mesenchymal tumors.
  • METHODS: The clinical and pathologic findings of 10 cases of osteomalacia or rickets-associated mesenchymal tumors were evaluated.
  • The tumor size ranged from 1 to 7 cm (mean size = 3.52 cm).
  • Microscopically, the tumors were composed of various mesenchymal cells, including spindled fibroblast-like cells, adipocytes, chondroid cells and mucinous cells.
  • On immunohistochemical study, the tumor cells were all positive for vimentin.
  • CONCLUSIONS: Most of the osteomalacia or rickets-associated tumors are either benign or low-grade malignant mesenchymal tumors.
  • They can be mistaken as other neoplasms due to the morphologic heterogeneity present.
  • [MeSH-major] Bone Neoplasms / pathology. Mesenchymoma / pathology. Osteomalacia / complications. Rickets / complications. Soft Tissue Neoplasms / pathology

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  • (PMID = 16536317.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Vimentin; 0 / smooth muscle actin, rat
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71. Angiero F: Ectomesenchymal chondromyxoid tumour of the tongue. A review of histological and immunohistochemical features. Anticancer Res; 2010 Nov;30(11):4685-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Ectomesenchymal chondromyxoid tumour (ECT) is a rare, benign neoplasm of uncertain histogenesis, which appears to exclusively involve the oral cavity, particularly the tongue.
  • Immunohistochemical expression of S100, glial fibrillary acidic protein and vimentin, very helpful in confirming diagnosis, suggest a probable mesenchymal and neural origin of this rare entity.
  • [MeSH-major] Chondroma / pathology. Mesenchymoma / pathology. Myxoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21115924.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Desmin; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins; 0 / Vimentin
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72. Trencsenyi G, Juhasz T, Bako F, Marian T, Pocsi I, Kertai P, Hunyadi J, Banfalvi G: Comparison of the tumorigenic potential of liver and kidney tumors induced by N-nitrosodimethylamine. Histol Histopathol; 2010 03;25(3):309-20
Hazardous Substances Data Bank. N-NITROSODIMETHYLAMINE .

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  • The aim of the study was to determine the tumorigenic potential of two cell lines established from N-nitrosodimethylamine induced rat hepatocarcinoma (HeDe) and mesenchymal renal tumors (NeDe).
  • Western blot analysis and whole body autoradiography were used to measure the 18FDG uptake of tumor cells.
  • Elevated 18FDG uptake was measured in both tumor cell lines.
  • Whole body autoradiography provided evidence that the uptake of 18FDG was lower in the necrotic inner part than in the more vascularized outer parts of primary hepatocarcinoma and mesenchymal renal tumors.
  • GLUT-1 overexpression in hepatocarcinoma tumor, and high levels of GLUT-3 were found in the NeDe cell line and in the mesenchymal renal tumor.
  • TGF-beta-1 was overexpressed in hepatocarcinoma and mesenchymal renal tumors.
  • Besides the tumorigenic potential of the hepatocarcinoma, the high metabolic activity of the renal tumor indicated by its 18FDG uptake, GLUT-3 and TGF-beta1 expression, the mesenchymal renal tumor induced by N-nitroso-dimethylamine is not a benign, but an an aggressive renal carcinoma.
  • [MeSH-major] Carcinoma, Hepatocellular / chemically induced. Dimethylnitrosamine / toxicity. Kidney Neoplasms / chemically induced. Liver Neoplasms / chemically induced. Mesenchymoma / chemically induced
  • [MeSH-minor] Analysis of Variance. Animals. Autoradiography. Biomarkers, Tumor / metabolism. Blotting, Western. Carcinogenicity Tests. Cell Cycle / physiology. Cell Line, Tumor. Flow Cytometry. Fluorodeoxyglucose F18 / metabolism. Glucose Transporter Type 1 / metabolism. Glucose Transporter Type 3 / metabolism. Immunohistochemistry. Kidney / diagnostic imaging. Kidney / metabolism. Liver / diagnostic imaging. Liver / metabolism. Microscopy, Fluorescence. Radionuclide Imaging. Rats. Transforming Growth Factor beta1 / metabolism

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  • (PMID = 20054803.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glucose Transporter Type 1; 0 / Glucose Transporter Type 3; 0 / Transforming Growth Factor beta1; 0Z5B2CJX4D / Fluorodeoxyglucose F18; M43H21IO8R / Dimethylnitrosamine
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73. Santeusanio G, Schiaroli S, Ortenzi A, Mulè A, Perrone G, Fadda G: Solitary fibrous tumour of thyroid: report of two cases with immunohistochemical features and literature review. Head Neck Pathol; 2008 Sep;2(3):231-5
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  • The differential diagnosis of thyroid SFT includes different types of spindle cell proliferation, benign and malignant mesenchymal tumours, medullary thyroid carcinoma, fasciitis-like papillary carcinoma, and undifferentiated (anaplastic) carcinoma.
  • However, the morphologic and immunohistochemical findings of SFT are so characteristic that this diagnosis seldom represent a difficulty.
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Carcinoma / diagnosis. Carcinoma, Medullary / diagnosis. Carcinoma, Papillary / diagnosis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Mesenchymoma / diagnosis. Middle Aged

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  • (PMID = 20614321.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807559
  • [Keywords] NOTNLM ; Immunohistochemistry / Review / Solitary fibrous tumour / Thyroid
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74. Takahashi Y, Suzuki M, Fukusato T: Plexiform angiomyxoid myofibroblastic tumor of the stomach. World J Gastroenterol; 2010 Jun 21;16(23):2835-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plexiform angiomyxoid myofibroblastic tumor of the stomach.
  • Plexiform angiomyxoid myofibroblastic tumor of the stomach is a unique mesenchymal tumor that we first described in 2007.
  • The tumor is very rare, and to date, only 18 cases confirmed by immunohistochemistry have been reported in the literature.
  • The tumors are located at the antrum in all cases, and grossly, the tumor is whitish to brownish or reddish, and forms a lobulated submucosal or transmural mass.
  • Microscopically, the tumor is characterized by a plexiform growth pattern, the proliferation of cytologically bland spindle cells, and a myxoid stroma that is rich in small vessels and positive for Alcian blue stain.
  • Immunohistochemically, the tumor cells are positive for alpha-smooth muscle actin and negative for KIT and CD34.
  • Differential diagnoses include gastrointestinal stromal tumor and other mesenchymal tumors of the gastrointestinal tract.
  • Some authors proposed that this tumor should be designated as "plexiform fibromyxoma", but this designation might cause confusion.
  • The tumor is probably benign and thus far, neither recurrence nor metastasis has been reported.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. DNA Mutational Analysis. Diagnosis, Differential. Female. Gastrointestinal Stromal Tumors / diagnosis. Humans. Immunohistochemistry. Male. Mesenchymoma / diagnosis. Middle Aged. Young Adult

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  • (PMID = 20556828.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Editorial; Review
  • [Publication-country] China
  • [Number-of-references] 24
  • [Other-IDs] NLM/ PMC2887578
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75. Wang Q, Zhang P, Zhang Q, Wang X, Li J, Ma C, Sun W, Zhang L: Analysis of CD137 and CD137L expression in human primary tumor tissues. Croat Med J; 2008 Apr;49(2):192-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Analysis of CD137 and CD137L expression in human primary tumor tissues.
  • AIM: To assess the expression of CD137 and CD137L in human primary tumor tissues and their potential role in tumor immunity.
  • METHODS: Expression of CD137 and CD137L was assessed by immunohistochemistry in frozen sections of 12 human normal tissues, 15 benign tumors of epithelial or mesenchymal origin (adenoma and leiomyoma), and 36 malignant tumors of epithelial origin (squamous cell carcinoma and adenocarcinoma).
  • The expression of CD137L on 9 human tumor cell lines (3 hepatocarcinoma, 2 lung carcinoma, 2 colon carcinoma, 1 lymphoma, and 1 leukemia) was detected by reverse transcription polymerase chain reaction.
  • To analyze the role of CD137L expressed on tumor cells, we co-cultured tumor cells expressing CD137L with activated T lymphocytes expressing CD137 or with Chinese hamster ovary cells expressing CD137 and then detected by ELISA the levels of cytokines (IL-8, IFN-gamma) secreted by tumor cells or activated T cells.
  • RESULTS: The expression of CD137 and CD137L was observed only in human benign (2/15, 3/15) or malignant tumors (15/36, 21/36), but not in normal tissues (0/12, 0/12).
  • CD137 was expressed on the vessel walls within tumor tissues, whereas CD137L was expressed on tumor cells.
  • Furthermore, CD137L expression found on tumor cell lines was functional because the ligation of CD137L on lung squamous carcinoma cells L78 with CD137 on T cells induced IFN-gamma production by T cells, and ligation of CD137L on hepatocarcinoma cells HepG2.2.15 with CD137 triggered tumor cells to produce IL-8.
  • CONCLUSION: CD137 and CD137L are expressed in different human primary tumor tissues, suggesting that they may influence the progression of tumors.
  • [MeSH-major] 4-1BB Ligand / genetics. Antigens, CD137 / genetics. Carcinoma / genetics. Gene Expression. Mesenchymoma / genetics
  • [MeSH-minor] Cell Line, Tumor. Disease Progression. Humans. Immunohistochemistry. Signal Transduction. Tumor Cells, Cultured

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  • (PMID = 18461674.001).
  • [ISSN] 1332-8166
  • [Journal-full-title] Croatian medical journal
  • [ISO-abbreviation] Croat. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / 4-1BB Ligand; 0 / Antigens, CD137
  • [Other-IDs] NLM/ PMC2359873
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76. Padilla-Rodriguez AL, Padilla-Villalta A, Arandia Y: Synchronous benign and malignant mesenchymal breast tumor. Breast J; 2007 May-Jun;13(3):314-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous benign and malignant mesenchymal breast tumor.
  • [MeSH-major] Breast Neoplasms / pathology. Liposarcoma, Myxoid / pathology. Mesenchymoma / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Breast Diseases / pathology. Female. Fibroma / pathology. Granular Cell Tumor / pathology. Humans. Middle Aged

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  • (PMID = 17461913.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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