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1. Sekar S, Kuruvila M, Pai HS: Nevus of Ota: a series of 15 cases. Indian J Dermatol Venereol Leprol; 2008 Mar-Apr;74(2):125-7
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  • [Title] Nevus of Ota: a series of 15 cases.
  • BACKGROUND: The nevus of Ota is a dermal nevus characterized by bluish pigmentation in the distribution of the first and the second division of the trigeminal nerve.
  • AIM: Our aim was to study the cutaneous and extracutaneous manifestations of the nevus of Ota.
  • A few rarer associations such as nevus of Ito and hemangioma were also noted in our patients.
  • [MeSH-major] Nevus of Ota / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18388370.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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2. Presentations of the damned I. Mole. By Caveman. J Cell Sci; 2008 Jul 15;121(Pt 14):2277-8
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  • [Title] Presentations of the damned I. Mole. By Caveman.

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  • (PMID = 18754145.001).
  • [ISSN] 0021-9533
  • [Journal-full-title] Journal of cell science
  • [ISO-abbreviation] J. Cell. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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3. Henning JS, Dusza SW, Wang SQ, Marghoob AA, Rabinovitz HS, Polsky D, Kopf AW: The CASH (color, architecture, symmetry, and homogeneity) algorithm for dermoscopy. J Am Acad Dermatol; 2007 Jan;56(1):45-52
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  • Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms.
  • METHODS: A total CASH score (TCS) was calculated for dermoscopic images of 325 melanocytic neoplasms.
  • RESULTS: The mean TCS was 12.28 for melanoma, 7.62 for dysplastic nevi, and 5.24 for nondysplastic nevi.
  • A TCS of 8 or more yielded a sensitivity of 98% and specificity of 68% for the diagnosis of melanoma.
  • CONCLUSIONS: The CASH algorithm can distinguish melanoma from melanocytic nevi with sensitivity and specificity comparable with other algorithms.
  • [MeSH-major] Algorithms. Dermoscopy / standards. Melanoma / ultrastructure. Skin Neoplasms / ultrastructure
  • [MeSH-minor] Area Under Curve. Cross-Sectional Studies. Diagnosis, Differential. Melanocytes / ultrastructure. Nevus, Pigmented / congenital. Nevus, Pigmented / diagnosis. Nevus, Pigmented / ultrastructure. Pigmentation. Pilot Projects. Predictive Value of Tests. ROC Curve. Reproducibility of Results. Severity of Illness Index

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  • (PMID = 17190620.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] United States
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4. Yoon H, Oostrom M, Werth CJ: Estimation of interfacial tension between organic liquid mixtures and water. Environ Sci Technol; 2009 Oct 15;43(20):7754-61
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  • Seven models are evaluated: the ideal and nonideal monolayer models (MLID and MLNID), the ideal and nonideal mutual solubility models (MSID and MSNID), an empirical model for ternary systems (EM), a linear mixing model based on mole fractions (LMMM), and a newly developed linear mixing model based on volume fractions of organic mixtures (LMMV) for higher order systems.

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  • (PMID = 19921890.001).
  • [ISSN] 0013-936X
  • [Journal-full-title] Environmental science & technology
  • [ISO-abbreviation] Environ. Sci. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organic Chemicals; 059QF0KO0R / Water
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5. Cheema MA, Taboada P, Barbosa S, Castro E, Siddiq M, Mosquera V: Energetics and conformational changes upon complexation of a phenothiazine drug with human serum albumin. Biomacromolecules; 2007 Aug;8(8):2576-85
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  • Gibbs energies of drug binding per mole of drug were also derived from zeta-potential data.

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  • (PMID = 17592874.001).
  • [ISSN] 1525-7797
  • [Journal-full-title] Biomacromolecules
  • [ISO-abbreviation] Biomacromolecules
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Phenothiazines; 0 / Serum Albumin; GS9EX7QNU6 / phenothiazine
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6. Shew SB, Keshen TH, Jahoor F, Jaksic T: Assessment of cysteine synthesis in very low-birth weight neonates using a [13C6]glucose tracer. J Pediatr Surg; 2005 Jan;40(1):52-6
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  • When expressed as a product/precursor ratio, the mole percent above baseline of [13C]apo B-100 cysteine/[13C6]glucose correlated with birth weight (r = 0.74, P < .01).

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  • (PMID = 15868558.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apolipoprotein B-100; 0 / Apolipoproteins B; 0 / Carbon Isotopes; IY9XDZ35W2 / Glucose; K848JZ4886 / Cysteine
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7. Xu B, Lynn GW, Guo J, Melnichenko YB, Wignall GD, McClain JB, Desimone JM, Johnson CS Jr: NMR and SANS studies of aggregation and microemulsion formation by phosphorus fluorosurfactants in liquid and supercritical carbon dioxide. J Phys Chem B; 2005 May 26;109(20):10261-9
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  • The observed dependence of the relaxation time (T(2)) on W(0) (mole ratio of water to surfactant in the droplets) for water and NH(4)(+) can also be explained by this exchange model.

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  • (PMID = 16852243.001).
  • [ISSN] 1520-6106
  • [Journal-full-title] The journal of physical chemistry. B
  • [ISO-abbreviation] J Phys Chem B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Premalata CS, Kumar RV, Malathi M, Shenoy AM, Nanjundappa N: Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus. Int J Dermatol; 2007 Mar;46(3):306-8
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  • [Title] Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus.
  • The specimen of the initial surgery consisted of skin-covered tissue with an exophytic firm growth measuring 6 x 5 x 4 cm.
  • The skin surface was rough with areas of ulceration.
  • The third lesion was a spindle cell sarcoma which formed the major part of the lesion, diffusely infiltrating the dermis and subcutaneous tissue, elevating and ulcerating the overlying skin.
  • A small area of epidermal hyperplasia with acanthosis and papillomatosis overlying malformed highly placed sebaceous glands was the only evidence of a pre-existing nevus sebaceus.
  • The wide excision specimen of the recurrent swelling consisted of a skin-covered nodule with ulceration, measuring 3 x 4 x 3 cm, with a gray-white whorled cut surface.
  • Multiple sections showed only spindle cell sarcoma infiltrating the skin and subcutaneous tissue, morphologically similar to the earlier tumor, with ulceration of the overlying skin.
  • Correlating the histomorphology and immunohistochemical findings, a diagnosis of cutaneous leiomyosarcoma with tricho-blastoma and syringocystadenoma papilliferum arising on nevus sebaceus was made.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Nevus / pathology. Scalp. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


9. Mehta SK, Bhawna, Ram G: Behavior of papain in mixed micelles of anionic-cationic surfactants having similar tails and dissimilar head groups. J Colloid Interface Sci; 2010 Apr 1;344(1):105-11
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  • The mixed micellar behavior of anionic surfactant, sodium dodecylsulfate (SDS) and cationic surfactant, dodecylethyldimethylammonium bromide (DDAB) at varying mole fractions of DDAB, i.e. alpha(DDAB) in aqueous solution of papain has been investigated with the aid of spectroscopy and physiochemical measurements.
  • Thermodynamic parameters have been computed over the entire mole fraction range of DDAB.
  • The results show that lower and higher mole fractions of DDAB give negative departure from ideality whereas intermediate mole fractions have positive deviation.
  • The turbidity or cloudiness at intermediate mole fractions demonstrates a reduction in the background free monomer concentration due to neutralization of the monomers of opposite charge.

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  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • (PMID = 20074744.001).
  • [ISSN] 1095-7103
  • [Journal-full-title] Journal of colloid and interface science
  • [ISO-abbreviation] J Colloid Interface Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ions; 0 / Micelles; 0 / Quaternary Ammonium Compounds; 0 / Surface-Active Agents; 13146-86-6 / didodecyldimethylammonium; 368GB5141J / Sodium Dodecyl Sulfate; EC 3.4.22.2 / Papain
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10. Sasirekha V, Vanelle P, Terme T, Meenakshi C, Umadevi M, Ramakrishnan V: Solvatochromism, preferential solvation of 2,3-bis(chloromethyl)-1,4-anthraquinone in binary mixtures and the molecular recognition towards p-tert-butyl-calix[4]arene. J Fluoresc; 2007 Sep;17(5):528-39
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  • This can be elucidated from the local mole fraction, non-linearity in transition energy plot, preferential solvation index (delta (s2)) and (f2/f1) values.


11. Landolsi H, Missaoui N, Yacoubi MT, Trabelsi A, Rammeh-Rommani S, Hidar S, Gribaa M, Hmissa S, Mokni M: Assessment of the role of histopathology and DNA image analysis in the diagnosis of molar and non-molar abortion: a study of 89 cases in the center of Tunisia. Pathol Res Pract; 2009;205(11):789-96
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  • This study retrospectively evaluated the histopathological criteria commonly used in the literature on the diagnosis of hydatidiform mole, in correlation with the diagnosis rendered previously.
  • We retrospectively studied 89 specimens of abortus conception, including 35 complete hydatidiform moles (CHM), 12 partial hydatidiform moles (PHM), and 42 hydropic abortions (HA).
  • [MeSH-major] Abortion, Spontaneous / diagnosis. DNA. Hydatidiform Mole / diagnosis

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  • (PMID = 19665315.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 9007-49-2 / DNA
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12. Olsher M, Yoon SI, Chong PL: Role of sterol superlattice in free radical-induced sterol oxidation in lipid membranes. Biochemistry; 2005 Feb 15;44(6):2080-7
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  • These mole fractions correspond to the critical sterol mole fractions C(r) predicted for maximal sterol superlattice formation.
  • In three-component bilayers composed of POPC, cholesterol, and DHE (fixed at 1 and 5 mol %), the initial rate of AAPH-induced DHE oxidation exhibited a biphasic change whenever the total sterol mole fraction, irrespective of the DHE content, was near C(r), indicating that the correlation between sterol oxidation and sterol superlattice formation revealed in this study is not an artifact due to the use of the fluorescent cholesterol analogue DHE.

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  • (PMID = 15697233.001).
  • [ISSN] 0006-2960
  • [Journal-full-title] Biochemistry
  • [ISO-abbreviation] Biochemistry
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amidines; 0 / Free Radicals; 0 / Lipid Bilayers; 0 / Phosphatidylcholines; 0 / Sphingomyelins; 0 / Sterols; 123R6KJQ51 / dehydroergosterol; 13217-66-8 / 2,2'-azobis(2-amidinopropane); 97C5T2UQ7J / Cholesterol; TE895536Y5 / 1-palmitoyl-2-oleoylphosphatidylcholine; Z30RAY509F / Ergosterol
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13. Huang CY, Tsai TC, Thomas JL, Lee MH, Liu BD, Lin HY: Urinalysis with molecularly imprinted poly(ethylene-co-vinyl alcohol) potentiostat sensors. Biosens Bioelectron; 2009 Apr 15;24(8):2611-7
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  • The mole ratio of ethylene to vinyl alcohol affected the performance: 27 mol% ethylene gave the highest imprinting effectiveness for creatinine and urea, while 44 mol% gave the highest effectiveness for lysozyme.

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  • (PMID = 19230648.001).
  • [ISSN] 1873-4235
  • [Journal-full-title] Biosensors & bioelectronics
  • [ISO-abbreviation] Biosens Bioelectron
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Polyvinyls; 25067-34-9 / ethylene-vinyl alcohol copolymer
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14. Horner BM, El-Muttardi NS, Mayou BJ: Treatment of congenital melanocytic naevi with CO2 laser. Ann Plast Surg; 2005 Sep;55(3):276-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of congenital melanocytic naevi with CO2 laser.
  • This study assesses the effectiveness of CO2 laser in treating congenital melanocytic naevi (CMN).
  • In all cases, there was minimal visible naevus after treatment.
  • [MeSH-major] Carbon Dioxide. Laser Therapy / methods. Nevus, Pigmented / congenital. Nevus, Pigmented / surgery

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  • [CommentIn] Ann Plast Surg. 2006 Feb;56(2):222-4 [16432339.001]
  • (PMID = 16106167.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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15. Zalaudek I, Sgambato A, Ferrara G, Argenziano G: Diagnosis and management of melanocytic skin lesion in the pediatric praxis. A review of the literature. Minerva Pediatr; 2008 Jun;60(3):291-312
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  • [Title] Diagnosis and management of melanocytic skin lesion in the pediatric praxis. A review of the literature.
  • Children may present a variable spectrum of melanocytic skin lesions and the great majority of them is benign.
  • Childhood melanoma is still exceptionally rare, although recent data suggest an increasing incidence even in young age.
  • The optimal management of children presenting with melanocytic skin lesions aims therefore to a twofold goal, that is to reduce unnecessary surgical excisions of benign melanocytic nevi without running the risk to miss melanoma.
  • It comes therefore not as a surprise that dermoscopy has gained popularity for the diagnosis and management of pigmented and nonpigmented skin lesions in the pediatric praxis.
  • In this article, we provide a review of the current literature on dermoscopy patterns of melanocytic skin lesions and their management with special emphasis to a pediatric population.
  • Moreover, we discuss recent concepts regarding nevogenesis and highlight some controversial aspects regarding childhood melanoma.
  • [MeSH-major] Melanoma / pathology. Nevus / pathology. Skin Neoplasms / pathology


16. Kang H, Kim SE, Park K, Son SJ, Song KY: Nevus lipomatosus cutaneous superficialis with folliculosebaceous cystic hamartoma. J Am Acad Dermatol; 2007 Feb;56(2 Suppl):S55-7
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  • [Title] Nevus lipomatosus cutaneous superficialis with folliculosebaceous cystic hamartoma.
  • [MeSH-major] Cysts / complications. Hamartoma / complications. Lipomatosis / complications. Nevus / complications. Skin Diseases / complications. Skin Neoplasms / complications


17. Tan C, Zhu WY, Ming ZS: Partial depigmentation arise in the naevus of Ito. J Eur Acad Dermatol Venereol; 2006 Nov;20(10):1331-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Partial depigmentation arise in the naevus of Ito.
  • [MeSH-major] Hypopigmentation / pathology. Nevus, Pigmented / pathology. Skin Neoplasms / pathology

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  • (PMID = 17062057.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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18. Kang HS, Park JE, Lee YJ, Chang IS, Chung YI, Tae G: Preparation of liposomes containing oleanolic acid via micelle-to-vesicle transition. J Nanosci Nanotechnol; 2007 Nov;7(11):3944-8
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  • The optimal loading of oleanolic acid to lecithin (about 25 mole%) was found to exist to produce liposomal suspension of small size without homogenization step.

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  • (PMID = 18047093.001).
  • [ISSN] 1533-4880
  • [Journal-full-title] Journal of nanoscience and nanotechnology
  • [ISO-abbreviation] J Nanosci Nanotechnol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Colloids; 0 / Liposomes; 0 / Macromolecular Substances; 0 / Micelles; 6SMK8R7TGJ / Oleanolic Acid
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19. Beachkofsky TM, Sapp JC, Biesecker LG, Darling TN: Progressive overgrowth of the cerebriform connective tissue nevus in patients with Proteus syndrome. J Am Acad Dermatol; 2010 Nov;63(5):799-804
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  • [Title] Progressive overgrowth of the cerebriform connective tissue nevus in patients with Proteus syndrome.
  • BACKGROUND: Proteus syndrome is a rare overgrowth disorder that almost always affects the skin.
  • OBJECTIVE: Our purpose was to evaluate progression of skin lesions in patients with Proteus syndrome.
  • METHODS: Skin findings were documented in 36 patients with Proteus syndrome.
  • Progression of skin lesions in 16 of these patients was assessed by comparing photographs obtained on repeated visits for an average total duration of 53 months.
  • RESULTS: The skin lesion most characteristic of Proteus syndrome, the cerebriform connective tissue nevus, showed progression in 13 children but not in 3 adults.
  • The cerebriform connective tissue nevus progressed by expansion into previously uninvolved skin, increased thickness, and development of new lesions.
  • In contrast, epidermal nevi and vascular malformations generally did not spread or increase in number.
  • CONCLUSION: The cerebriform connective tissue nevus in Proteus syndrome grows throughout childhood but tends to remain stable in adulthood.
  • [MeSH-major] Connective Tissue / pathology. Epidermis / pathology. Nevus / pathology. Proteus Syndrome / pathology. Skin Neoplasms / pathology

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  • [Copyright] Copyright © 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
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  • (PMID = 20709429.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA HG200328-07
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS341425; NLM/ PMC3240941
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20. Deng SS, Ding ZM, Qian JH, Lü WG, Wan XY, Xie X: [Study on parental origin of complete hydatidiform mole detected by polymorphisms of microsatellite]. Zhonghua Fu Chan Ke Za Zhi; 2007 Jul;42(7):468-71
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  • [Title] [Study on parental origin of complete hydatidiform mole detected by polymorphisms of microsatellite].
  • OBJECTIVE: Through detection of 9 loci of polymorphisms of microsatellite to investigate the parental origin of complete hydatidiform mole.
  • METHODS: Using the technology and method of multipolymerase chain reaction and electrophoresis in denatured polyacrylamide gel and silver stain detection, we carried out DNA analysis on 50 cases of complete hydatidiform mole diagnosed by histopathology and 50 copies of the couples' peripheral blood.
  • RESULTS: There are 7 cases of biparental complete hydatidiform mole (14%); and 43 cases of androgenetic complete hydatidiform mole (86%) among 50 cases of complete hydatidiform mole.
  • CONCLUSIONS: Detection of polymorphisms of microsatellite is a technology that can be used to identify the parental origin of complete hydatidiform mole.
  • [MeSH-major] Hydatidiform Mole / genetics. Microsatellite Repeats / genetics. Polymorphism, Genetic. Uterine Neoplasms / genetics
  • [MeSH-minor] Adult. DNA, Neoplasm / genetics. Female. Humans. Karyotyping. Polymerase Chain Reaction / methods. Pregnancy. Reproducibility of Results. Sensitivity and Specificity

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  • (PMID = 17961337.001).
  • [ISSN] 0529-567X
  • [Journal-full-title] Zhonghua fu chan ke za zhi
  • [ISO-abbreviation] Zhonghua Fu Chan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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21. Markland FS, Swenson S: Fibrolase: trials and tribulations. Toxins (Basel); 2010 04;2(4):793-808
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  • The purified enzyme is a zinc metalloproteinase containing one mole of zinc.
  • Fibrolase rapidly cleaves the A(α)-chain of fibrinogen and the B(β)-chain at a slower rate; it has no activity on the γ-chain.

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  • (PMID = 22069611.001).
  • [ISSN] 2072-6651
  • [Journal-full-title] Toxins
  • [ISO-abbreviation] Toxins (Basel)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Fibrinolytic Agents; EC 3.4.24.- / Metalloendopeptidases; EC 3.4.24.- / alfimeprase; EC 3.4.24.- / fibrolase
  • [Other-IDs] NLM/ PMC3153196
  • [Keywords] NOTNLM ; alfimeprase (major topic) / alpha2 macroglobulin (major topic) / animal models (major topic) / central venous access device occlusion (major topic) / fibrolase (major topic) / metalloproteinase (major topic) / peripheral arterial occlusion (major topic) / stroke (major topic) / thrombolysis (major topic)
  • [General-notes] NLM/ Original DateCompleted: 20111110
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22. Horkay F, Basser PJ, Londono DJ, Hecht AM, Geissler E: Ions in hyaluronic acid solutions. J Chem Phys; 2009 Nov 14;131(18):184902
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  • An equation of state is derived for the osmotic pressure Pi in the semidilute concentration region, in terms of two variables, the polymer concentration c and the ionic strength J of the added salt, according to which Pi=1.4x10(3)c(9/4)/J(3/4) kPa, where c and J are expressed in mole.

  • Hazardous Substances Data Bank. CALCIUM CHLORIDE .
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  • (PMID = 19916626.001).
  • [ISSN] 1089-7690
  • [Journal-full-title] The Journal of chemical physics
  • [ISO-abbreviation] J Chem Phys
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biopolymers; 0 / Ions; 0 / Solutions; 451W47IQ8X / Sodium Chloride; 9004-61-9 / Hyaluronic Acid; M4I0D6VV5M / Calcium Chloride
  • [Other-IDs] NLM/ PMC2792326
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23. Harnisch H, Paredes BE, Spieler P, Bornstein MM: [White sponge naevus. Report of a family with respect to histopathologic, cytopathologic and DNA-cytometric aspects]. Schweiz Monatsschr Zahnmed; 2006;116(11):1130-44
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  • [Title] [White sponge naevus. Report of a family with respect to histopathologic, cytopathologic and DNA-cytometric aspects].
  • The white sponge naevus is a rare benign, hereditary autosomal dominant disorder of the mucosa.
  • A potential risk for malignant transformation of white sponge naevus lesions has not been reported.
  • The therapy for this benign hereditary disorder is unknown, however does not appear to be necessary.
  • In the present report of a family with known white sponge naevus in three different generations, clinical, histopathologic, cytopathologic, DNA-cytomertric, and genetic aspects are described and discussed.

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  • (PMID = 17144625.001).
  • [ISSN] 0256-2855
  • [Journal-full-title] Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia
  • [ISO-abbreviation] Schweiz Monatsschr Zahnmed
  • [Language] FRE; GER
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
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24. Singh AK, Singh SK, Mishra H, Prakash R, Rai SB: Structural, thermal, and fluorescence properties of Eu(DBM)(3)Phen(x) complex doped in PMMA. J Phys Chem B; 2010 Oct 21;114(41):13042-51
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  • X-ray analysis reveals an unusual crystalline to amorphous transformation in structure of the Eu(DBM)(3)Phen(x) complexes when x exceeds 1.0 (mole %).
  • A systematic and significant improvement in the thermal and fluorescence properties of the complex is observed with an increase in the mole concentration of Phen.

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  • (PMID = 20873745.001).
  • [ISSN] 1520-5207
  • [Journal-full-title] The journal of physical chemistry. B
  • [ISO-abbreviation] J Phys Chem B
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organometallic Compounds; 0 / Phenanthrolines; 0 / europium-tris(dibenzoylmethane)-1,10-phenanthroline; 9011-14-7 / Polymethyl Methacrylate
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25. Boyle NR, Morgan JA: Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii. BMC Syst Biol; 2009;3:4
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  • Biomass yields ranged from 28.9 g per mole C for autotrophic growth to 15 g per mole C for heterotrophic growth.

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  • (PMID = 19128495.001).
  • [ISSN] 1752-0509
  • [Journal-full-title] BMC systems biology
  • [ISO-abbreviation] BMC Syst Biol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2628641
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26. Gensure RH, Zeidel ML, Hill WG: Lipid raft components cholesterol and sphingomyelin increase H+/OH- permeability of phosphatidylcholine membranes. Biochem J; 2006 Sep 15;398(3):485-95
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  • SM at 10 mole% effected a 2.8-fold increase (P<0.01), whereas 20 and 30 mole% enhanced permeability by 3.6-fold (P<0.05) and 4.1-fold respectively (P<0.05).

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  • (PMID = 16706750.001).
  • [ISSN] 1470-8728
  • [Journal-full-title] The Biochemical journal
  • [ISO-abbreviation] Biochem. J.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK043955; United States / NIDDK NIH HHS / DK / R37 DK048217; United States / NIDDK NIH HHS / DK / DK-43955; United States / NIDDK NIH HHS / DK / DK-48217
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hydroxides; 0 / Liposomes; 0 / Phosphatidylcholines; 0 / Protons; 0 / Sphingomyelins; 1405-97-6 / Gramicidin; 9159UV381P / hydroxide ion; 97C5T2UQ7J / Cholesterol
  • [Other-IDs] NLM/ PMC1559473
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27. Moreno D, Ferrándiz L, Pérez-Bernal AM, Ríos JJ, Carrasco R, Camacho F: [Evaluation of a screening system for patients with pigmented lesions using store-and-forward teleconsultation]. Actas Dermosifiliogr; 2005 May;96(4):222-30
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  • Teleconsultation patients reported changes in a pigmented lesion, a lesion that had recently appeared, multiple lesions, symptomatic lesions or concern about a nevus.
  • The most frequent reason for the teleconsultation was concern about a nevus (37.0 %).
  • However, more experience is needed to establish the true usefulness of this filtering system in the early diagnosis of melanoma.
  • [MeSH-major] Hyperpigmentation / diagnosis. Patient Selection. Remote Consultation. Skin Neoplasms / diagnosis

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  • (PMID = 16476372.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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28. Weatherhead SC, Haniffa M, Lawrence CM: Melanomas arising from naevi and de novo melanomas--does origin matter? Br J Dermatol; 2007 Jan;156(1):72-6
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  • The proportions involved and the effect of melanoma origin on prognosis is unclear.
  • OBJECTIVES: To determine whether melanomas reported by the patient to have developed from a pre-existing naevus are associated with a better or worse prognosis compared with those arising de novo when adjusted for confounding variables.
  • METHODS: All patients attending a dedicated melanoma screening clinic between March 1997 and March 2002 were included.
  • The distinction between melanoma arising without any pre-existing lesion (de novo) and those derived from a pre-existing lesion (naevus melanoma) was based on patient history.
  • We categorized patients into three groups: those who gave a history of their lesion arising within a pre-existing naevus, those in whom the melanoma developed de novo and those in whom no conclusive history could be obtained.
  • We compared prognostic indicators between the naevus and de novo melanoma groups.
  • RESULTS: Of 8593 patients screened, 377 had a positive diagnosis of melanoma (in situ or invasive).
  • Of these 42% had naevus melanomas, 34% new melanomas and 24% were uncertain.
  • Patients presenting with a melanoma arising from a pre-existing naevus had a greater Breslow thickness despite presenting sooner than the de novo group, although no significant difference in thickness was found when other prognostic factors were controlled for.
  • [MeSH-major] Genetic Predisposition to Disease / genetics. Melanoma / etiology. Nevus / etiology. Skin Neoplasms / etiology

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  • [CommentIn] Br J Dermatol. 2009 Sep;161(3):700-2 [19575730.001]
  • (PMID = 17199569.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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29. Galliker B, Kissner R, Nauser T, Koppenol WH: Intermediates in the autoxidation of nitrogen monoxide. Chemistry; 2009 Jun 15;15(25):6161-8
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  • From the semiquantitative determination of mole fractions present in the gas phase by EPR spectroscopy, we estimated the rate constants for the steps that lead to ONOO* and ONOONO, from the known overall rate constant of the autoxidation reaction, by assuming that a quasi-stationary mechanism applies.
  • The rate constant for the rate-determining formation of ONOO* is about 3.1 x 10(-18) cm3 molecule(-1) s(-1) (or 80 s(-1) in mole fractions), the dissociation rate constant of ONOO* is about 6.5 x 10(3) s(-1), and ONOONO is formed with a rate constant of k=7.7 x 10(-14) cm3 molecule(-1) s(-1) (1.9 x 10(6) s(-1) in mole fractions).

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  • (PMID = 19437472.001).
  • [ISSN] 1521-3765
  • [Journal-full-title] Chemistry (Weinheim an der Bergstrasse, Germany)
  • [ISO-abbreviation] Chemistry
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Gases; 0 / Oxidants; 0 / Pentanes; 31C4KY9ESH / Nitric Oxide; ZH67814I0O / isopentane
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30. Zhang JM, Yang ZW, Chen RY, Gao P, Zhang YR, Zhang LF: Two new mutations in the keratin 4 gene causing oral white sponge nevus in Chinese family. Oral Dis; 2009 Jan;15(1):100-5
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  • [Title] Two new mutations in the keratin 4 gene causing oral white sponge nevus in Chinese family.
  • OBJECTIVE: We investigated white sponge nevus (WSN) in a Chinese family, and tried to find new mutation and demonstrated that this mutation is the causative mutation for WSN in this family and this condition affects a functionally important segment of the keratin 4 protein.

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  • (PMID = 18992023.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / KRT13 protein, human; 0 / Keratin-13; 0 / Keratin-4; 0 / RNA, Untranslated; 3KX376GY7L / Glutamic Acid; 5Z93L87A1R / Guanine; JAC85A2161 / Adenine; K3Z4F929H6 / Lysine
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31. Massone C, Brunasso AM, Campbell TM, Soyer HP: Mobile teledermoscopy--melanoma diagnosis by one click? Semin Cutan Med Surg; 2009 Sep;28(3):203-5
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  • [Title] Mobile teledermoscopy--melanoma diagnosis by one click?
  • Mobile teledermatology may provide a triage service aimed toward management of patients with emergent skin disease or for follow-up with patients requiring systemic treatment.
  • Further to this, telediagnosis of melanocytic skin neoplasms achieved a diagnostic accuracy of 83% versus the conventional histopathologic diagnosis.
  • Such applications are of benefit to physicians in enabling easy storage of data for follow-up or referral of images for expert second opinion and may facilitate a "person-centered health system" for patients with numerous moles and pigmented skin lesions who could forward images for evaluation.
  • The incidence of skin cancers has reached epidemic proportions among whites and the trend is still going upward.
  • [MeSH-major] Dermoscopy. Melanoma / pathology. Mobile Health Units. Telemedicine

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  • (PMID = 19782945.001).
  • [ISSN] 1558-0768
  • [Journal-full-title] Seminars in cutaneous medicine and surgery
  • [ISO-abbreviation] Semin Cutan Med Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Zhuang JM, Hobenshield E, Walsh T: Fe-As sludge stability and effluent quality for a two-stage As-contaminated water treatment with Fe(II) and aeration. Environ Technol; 2009 Feb;30(2):199-213
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  • In stage I, using an Fe/As mole ratio of 1.5-2.5 at a pH of around 6.5-7.5, the dissolved arsenic can be reduced with Fe(II) oxidation-precipitation from an initial 72 mg L(-1) to < 2 mg L(-1).

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  • (PMID = 19278161.001).
  • [ISSN] 0959-3330
  • [Journal-full-title] Environmental technology
  • [ISO-abbreviation] Environ Technol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Validation Studies
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Metals; 0 / Sewage; 059QF0KO0R / Water; 8062-15-5 / lignosulfuric acid; 9005-53-2 / Lignin; E1UOL152H7 / Iron; N712M78A8G / Arsenic
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33. Farago O, Ewert K, Ahmad A, Evans HM, Grønbech-Jensen N, Safinya CR: Transitions between distinct compaction regimes in complexes of multivalent cationic lipids and DNA. Biophys J; 2008 Jul;95(2):836-46
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  • At low mole fraction of neutral lipids (NLs), Phi(NL), the complexes show dramatic DNA compaction, down to essentially close-packed DNA arrays with a DNA interaxial spacing d(DNA) = 25 A.

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  • (PMID = 18390608.001).
  • [ISSN] 1542-0086
  • [Journal-full-title] Biophysical journal
  • [ISO-abbreviation] Biophys. J.
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM059288; United States / NIGMS NIH HHS / GM / GM-59288
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cations; 0 / Lipids; 9007-49-2 / DNA
  • [Other-IDs] NLM/ PMC2440430
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34. Kolokythas A, Fernandes RP, Pazoki A, Ord RA: Odontogenic keratocyst: to decompress or not to decompress? A comparative study of decompression and enucleation versus resection/peripheral ostectomy. J Oral Maxillofac Surg; 2007 Apr;65(4):640-4
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  • Three of these patients diagnosed with basal cell nevus syndrome and multiple OKCs and 6 patients who did not have adequate follow-up were excluded from this study; thus, 22 patients were evaluated.

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  • (PMID = 17368357.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 68238-35-7 / Keratins
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35. Cleveland DB, Rinaggio J, Schneider LC, UMDNJ-New Jersey Dental School Biopsy Service: Oral pathology quiz #49. Case number 4. Melanocytic nevus. J N J Dent Assoc; 2005;76(4):27, 41
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  • [Title] Oral pathology quiz #49. Case number 4. Melanocytic nevus.
  • [MeSH-major] Nevus, Pigmented / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16433302.001).
  • [ISSN] 0093-7347
  • [Journal-full-title] Journal of the New Jersey Dental Association
  • [ISO-abbreviation] J N J Dent Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Ogilvie CM, Renwick PJ, Khalaf Y, Braude PR: First use of preimplantation genotyping in prevention of recurrent diandric complete hydatidiform mole. Reprod Biomed Online; 2009 Aug;19(2):224-7
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  • [Title] First use of preimplantation genotyping in prevention of recurrent diandric complete hydatidiform mole.
  • Complete hydatidiform moles have a diploid chromosome constitution, generally with only paternal genetic material present (diandry).
  • Diandric complete moles are thought to arise either by fertilization of an anucleate oocyte by two spermatozoa or, more commonly, doubling of a single sperm genotype.
  • This study presents the first use of preimplantation genotyping to ensure biparental inheritance in a woman presenting with recurrent diandric complete hydatidiform mole.
  • [MeSH-major] Blastocyst. Hydatidiform Mole / prevention & control

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  • (PMID = 19712559.001).
  • [ISSN] 1472-6491
  • [Journal-full-title] Reproductive biomedicine online
  • [ISO-abbreviation] Reprod. Biomed. Online
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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37. Shirke S, Takhistov P, Ludescher RD: Molecular mobility in amorphous maltose and maltitol from phosphorescence of erythrosin B. J Phys Chem B; 2005 Aug 25;109(33):16119-26
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  • We have used phosphorescence from erythrosin B (tetraiodofluorescein) dispersed in amorphous thin films of maltose and maltitol at mole ratios of 0.8:10(4) dye:sugar to monitor the molecular mobility of these matrixes over the temperature range from -25 to over 110 degrees C.

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  • (PMID = 16853048.001).
  • [ISSN] 1520-6106
  • [Journal-full-title] The journal of physical chemistry. B
  • [ISO-abbreviation] J Phys Chem B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Jonak C, Metze D, Traupe H, Happle R, König A, Trautinger F: The expression of the 27-kd heat shock protein in keratinization disorders: an immunohistological study. Hum Pathol; 2005 Jun;36(6):686-93
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  • In human skin, the 27-kd heat shock protein (hsp27), a member of the small hsp family, is expressed mainly in the upper epidermal layers.
  • Twelve hereditary and acquired skin diseases associated with an ichthyotic phenotype and 2 corresponding mouse models were investigated by immunohistochemistry on formalin-fixed paraffin-embedded tissue, using a monoclonal antibody specific for hsp27.
  • In ichthyosis vulgaris, lamellar ichthyosis, Sjögren-Larsson syndrome, Netherton syndrome, and acquired ichthyosiform skin condition, the pattern of hsp27 expression resembles healthy human skin.
  • Hsp27 expression was reduced in bullous ichthyosiform erythroderma and annular epidermolytic ichthyosis, and absent in X-linked recessive ichthyosis (1/3 patients) and congenital hemidysplasia with ichthyosiform nevus and limb defects syndrome (1/1).
  • In the mouse models, tattered and bare patches, representing the murine analogues to X-linked dominant chondrodysplasia and congenital hemidysplasia with ichthyosiform nevus and limb defects syndrome, expression of hsp25 (the murine homologue of hsp27) also showed lyonization, demonstrating a clear-cut link between hsp27 expression and underlying molecular pathology.
  • [MeSH-major] Heat-Shock Proteins / biosynthesis. Ichthyosis / metabolism. Neoplasm Proteins / biosynthesis

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  • (PMID = 16021576.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HSP27 Heat-Shock Proteins; 0 / HSPB1 protein, human; 0 / Heat-Shock Proteins; 0 / Neoplasm Proteins; 68238-35-7 / Keratins
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39. Fang Q, Shortle D: A consistent set of statistical potentials for quantifying local side-chain and backbone interactions. Proteins; 2005 Jul 1;60(1):90-6
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  • They vary from -0.4 - -0.5 kcal/mole per residue for phi/psi/chi1 propensities to a range of -0.15 - -0.6 kcal/mole per residue for each of the other 3 terms.

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  • (PMID = 15852305.001).
  • [ISSN] 1097-0134
  • [Journal-full-title] Proteins
  • [ISO-abbreviation] Proteins
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amino Acids; 0 / Proteins
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40. Abaffy T, Duncan R, Riemer DD, Tietje O, Elgart G, Milikowski C, DeFazio RA: Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process. PLoS One; 2010 Nov 04;5(11):e13813
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  • [Title] Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process.
  • BACKGROUND: Early detection of melanoma is of great importance to reduce mortality.
  • Discovering new melanoma biomarkers would improve early detection and diagnosis.
  • Here, we present a novel approach to detect volatile compounds from skin.
  • METHODS AND FINDINGS: We used Head Space Solid Phase Micro-Extraction (HS-SPME) and gas chromatography/mass spectrometry (GC/MS) to identify volatile signatures from melanoma, naevi and skin samples.
  • Volatiles released from fresh biopsy tissue of melanoma and benign naevus were compared based on their difference in frequency distribution and their expression level.
  • We also analyzed volatile profiles from frozen tissue, including skin and melanoma.
  • CONCLUSIONS: Three volatiles, 4-methyl decane, dodecane and undecane were preferentially expressed in both fresh and frozen melanoma, indicating that they are candidate biomarkers.
  • Twelve candidate biomarkers evaluated by fuzzy logic analysis of frozen samples distinguished melanoma from skin with 89% sensitivity and 90% specificity.
  • Our results demonstrate proof-of-principle that there is differential expression of volatiles in melanoma.
  • Our volatile metabolomic approach will lead to a better understanding of melanoma and can enable development of new diagnostic and treatment strategies based on altered metabolism.

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  • (PMID = 21079799.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA132046-02; United States / NCI NIH HHS / CA / R21 CA132046; United States / NCI NIH HHS / CA / R21CA 132046; United States / NCI NIH HHS / CA / R21 CA132046-01A1; United States / NCI NIH HHS / CA / R21 CA132046-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Volatile Organic Compounds
  • [Other-IDs] NLM/ PMC2973952
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41. Ikeda Y, Inagaki M, Yamada K, Miyamoto T, Higuchi R, Shibata O: Langmur monolayers of cerebroside with different head groups originated from sea cucumber: binary systems with dipalmitoylphosphatidylcholine (DPPC). Colloids Surf B Biointerfaces; 2009 Sep 1;72(2):272-83
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  • In addition, their miscibility with DPPC was examined by the variation of the molecular areas and the surface potentials as a function of cerebroside mole fractions, the additivity rule.


42. Chang X, Han J, Pang L, Zhao Y, Yang Y, Shen Z: Increased PADI4 expression in blood and tissues of patients with malignant tumors. BMC Cancer; 2009;9:40
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  • However, PADI4 expression was not observed in benign leiomyomas of stomach, uterine myomas, endometrial hyperplasias, cervical polyps, teratomas, hydatidiform moles, trophoblastic cell hyperplasias, hyroid adenomas, hemangiomas, lymph hyperplasias, schwannomas, neurofibromas, lipomas, and cavernous hemangiomas of the liver.
  • ELISA detected increased PADI4 and cAT levels in the blood of patients with various malignant tumors compared to those in patients with chronic inflammation and benign tumors.
  • [MeSH-major] Hydrolases / metabolism. Neoplasm Proteins / metabolism. Neoplasms / metabolism

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  • (PMID = 19183436.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antithrombins; 0 / Neoplasm Proteins; 29VT07BGDA / Citrulline; EC 3.- / Hydrolases; EC 3.5.3.15 / peptidylarginine deiminase type IV
  • [Other-IDs] NLM/ PMC2637889
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43. Azzam T, Eisenberg A: Monolayer-protected gold nanoparticles by the self-assembly of micellar poly(ethylene oxide)-b-poly(epsilon-caprolactone) block copolymer. Langmuir; 2007 Feb 13;23(4):2126-32
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  • Gold nanoparticles stabilized with the PEO-b-PCL block (named Au/Block (x/y), where x/y is the mole feed ratio between HAuCl4 and PEO-b-PCL-TE) were prepared and analyzed.

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  • (PMID = 17279704.001).
  • [ISSN] 0743-7463
  • [Journal-full-title] Langmuir : the ACS journal of surfaces and colloids
  • [ISO-abbreviation] Langmuir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Micelles; 0 / Polyesters; 059QF0KO0R / Water; 24980-41-4 / polycaprolactone; 30IQX730WE / Polyethylene Glycols; 7440-57-5 / Gold
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44. Chung TW, Liu DZ, Hsieh JH, Fan XC, Yang JD, Chen JH: Characterizing poly(epsilon-caprolactone)-b-chitooligosaccharide-b-poly(ethylene glycol) (PCP) copolymer micelles for doxorubicin (DOX) delivery: effects of crosslinked of amine groups. J Nanosci Nanotechnol; 2006 Sep-Oct;6(9-10):2902-11
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  • In addition, gel permeation chromatography (GPC) determines the number average molecular weight of the tri-block copolymers (Mn) of approximately 11340 Da/mole.

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  • (PMID = 17048497.001).
  • [ISSN] 1533-4880
  • [Journal-full-title] Journal of nanoscience and nanotechnology
  • [ISO-abbreviation] J Nanosci Nanotechnol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amines; 0 / Antineoplastic Agents; 0 / Cross-Linking Reagents; 0 / Drug Carriers; 0 / Macromolecular Substances; 0 / Micelles; 0 / Oligosaccharides; 0 / Polyesters; 0 / poly(epsilon-caprolactone-co-ethylene oxide); 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin; 9012-76-4 / Chitosan
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45. Er TK, Jong YJ, Tsai EM, Huang CL, Chou HW, Zheng BH, Tsai LY: False-negative pregnancy test in hydatidiform mole. Clin Chem; 2006 Aug;52(8):1616-8
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  • [Title] False-negative pregnancy test in hydatidiform mole.
  • [MeSH-major] Hydatidiform Mole / diagnosis. Uterine Neoplasms / diagnosis

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  • (PMID = 16873308.001).
  • [ISSN] 0009-9147
  • [Journal-full-title] Clinical chemistry
  • [ISO-abbreviation] Clin. Chem.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin
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46. Brychtova S, Fiuraskova M, Hlobilková A, Brychta T, Hirnak J: Nestin expression in cutaneous melanomas and melanocytic nevi. J Cutan Pathol; 2007 May;34(5):370-5
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  • [Title] Nestin expression in cutaneous melanomas and melanocytic nevi.
  • In this study, nestin expression was detected in both benign and malignant melanocytic skin lesions and its diagnostic relevance was then evaluated.
  • METHODS: Altogether 139 bioptic tissue samples consisting of 42 nodular melanomas, 32 superficial spreading melanomas, 12 metastatic melanomas, 10 dysplastic nevi and 43 common melanocytic intradermal and dermoepidermal nevi were analysed using indirect immunohistochemical staining.
  • [MeSH-major] Biomarkers, Tumor / analysis. Intermediate Filament Proteins / biosynthesis. Melanoma / metabolism. Nerve Tissue Proteins / biosynthesis. Nevus, Pigmented / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 17448190.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin
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47. Ha L, Ichikawa T, Anver M, Dickins R, Lowe S, Sharpless NE, Krimpenfort P, Depinho RA, Bennett DC, Sviderskaya EV, Merlino G: ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc Natl Acad Sci U S A; 2007 Jun 26;104(26):10968-73
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  • [Title] ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence.
  • But in the setting of melanoma, a highly aggressive and invariably fatal malignancy in its advanced disseminated form, mutation/deletion of p53 is relatively rare, whereas its positive regulator ARF is often lost.
  • Here, we show that genetic deficiency in Arf but not p53 facilitates rapid development of melanoma in a genetically engineered mouse model.
  • Our data demonstrate that ARF and p53, although linked in a common pathway, suppress tumorigenesis through distinct, lineage-dependent mechanisms and suggest that ARF helps restrict melanoma progression by executing the oncogene-induced senescence program in benign nevi.
  • Thus, therapeutics designed to restore wild-type p53 function may be insufficient to counter melanoma and other malignancies in which ARF holds p53-independent tumor suppressor activity.

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  • (PMID = 17576930.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748; United States / Intramural NIH HHS / / ; United Kingdom / Wellcome Trust / / 064583; United Kingdom / Wellcome Trust / / 078327; United States / NCI NIH HHS / CA / N01CO12400; United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p14ARF; 0 / Tumor Suppressor Protein p53; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras)
  • [Other-IDs] NLM/ PMC1904138
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48. Salma U, Imtiaz-ud-Din, Mazhar M, Khan KM: Germatranyl substituted organotin (IV) carboxylates: synthesis spectroscopic characterization and biological activities. Med Chem; 2009 Nov;5(6):543-8
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  • Eight new organotin (IV) derivatives of general formula [N(CH2CH2O)3GeCH(R1)CH2COO](4-n)SnR(2)n, where n= 2, R(2) = C2H5 (1-5); R(1) = CH3 (1); C6H5 (2); p-CH3C6H4 (3); p-FC6H4(4); p-CH3OC6H4 (5) and n = 3, R(2) = CH2C6H5 (6-8), R(1) = CH3 (6); C6H5 (7); p-CH3C6H4 (8) have been synthesized by the reaction of di- or tri-organotin chloride with the corresponding germatranyl (substituted) propionic acid in the appropriate mole ratios using triethylamine as a base.

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  • (PMID = 20041833.001).
  • [ISSN] 1875-6638
  • [Journal-full-title] Medicinal chemistry (Shāriqah (United Arab Emirates))
  • [ISO-abbreviation] Med Chem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antiprotozoal Agents; 0 / Carboxylic Acids; 0 / Ligands; 0 / Organotin Compounds
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49. Bataille V, Kato BS, Falchi M, Gardner J, Kimura M, Lens M, Perks U, Valdes AM, Bennett DC, Aviv A, Spector TD: Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo. Cancer Epidemiol Biomarkers Prev; 2007 Jul;16(7):1499-502
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  • [Title] Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo.
  • Nevus counts represent one of the strongest risk factors for melanoma.
  • Recent evidence has shown that nevus cells undergo oncogene-induced senescence involving the p16/retinoblastoma pathway.
  • This study explores whether telomere length measured in white cells is associated with nevus count and size in 1,897 Caucasian women ages 18 to 79 years.
  • Total body nevus counts were positively correlated with white cell telomere length (mean, 7.09 kbp; range, 5.09-9.37) after adjustment for age (P = 0.0001).
  • Age-adjusted telomere length was also associated with nevus count for nevi above 5 mm in diameter (P = 0.04).
  • Subjects in the top category for nevus count had an average age-adjusted telomere length 150 bp longer than those in the lowest category.
  • The positive correlation between white cell telomere length and nevi number and size may reflect an increased replicative potential (reduced senescence) in individuals with longer telomeres, which may not be melanocyte specific.
  • Understanding mechanisms influencing the induction and involution of nevi will not only help in understanding the pathophysiology of melanoma but should also shed light on the complex relationship between aging and cancer.
  • [MeSH-major] Biomarkers / metabolism. Nevus, Pigmented / pathology. Telomere / physiology

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  • (PMID = 17627017.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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50. García de Marcos JA, Dean-Ferrer A, Arroyo Rodríguez S, Calderón-Polanco J, Alamillos Granados FJ, Poblet E: Basal cell nevus syndrome: clinical and genetic diagnosis. Oral Maxillofac Surg; 2009 Dec;13(4):225-30
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  • [Title] Basal cell nevus syndrome: clinical and genetic diagnosis.
  • INTRODUCTION: Basal cell nevus syndrome (BCNS), also known as Gorlin-Goltz syndrome, comprises five main pathological features: nevoid basal cell carcinomas, keratocystic odontogenic tumors, congenital skeletal anomalies, calcification of the falx cerebri, and point skin depressions on the palms and/or soles.
  • [MeSH-major] Basal Cell Nevus Syndrome / genetics. Basal Cell Nevus Syndrome / pathology. Jaw Neoplasms / genetics. Jaw Neoplasms / pathology

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  • (PMID = 19795138.001).
  • [ISSN] 1865-1569
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Codon, Nonsense; 0 / PTCH protein, human; 0 / Patched Receptors; 0 / Patched-1 Receptor; 0 / Receptors, Cell Surface
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51. Albayrak M, Ozer A, Demir OF, Ozer S, Erkaya S: Complete mole coexistent with a twin fetus. Arch Gynecol Obstet; 2010 Jan;281(1):119-22
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  • [Title] Complete mole coexistent with a twin fetus.
  • INTRODUCTION: Complete hydatiforme mole with coexisting live fetus (CMCF) is a rare entity.
  • We report the delivery of a healthy baby coexisting with complete mole as twins.
  • Hydatiforme mole was suspected.
  • Histopathologic examination confirmed the diagnosis of complete mole.
  • CONCLUSION: Today most of the twin pregnancies with complete mole are identified in the first or second trimester.
  • [MeSH-major] Hydatidiform Mole. Live Birth

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  • (PMID = 19370357.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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52. Bachmann IM, Straume O, Puntervoll HE, Kalvenes MB, Akslen LA: Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin Cancer Res; 2005 Dec 15;11(24 Pt 1):8606-14
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  • [Title] Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma.
  • PURPOSE: It has been proposed that melanoma cells shift from E-cadherin to N-cadherin expression during tumor development, and recent gene profiling has shown increased expression of Wnt5a/Frizzled in aggressive melanomas possibly by interactions with beta-catenin.
  • We therefore wanted to investigate the role of cadherin subtypes, beta-catenin, and Wnt5a/Frizzled in melanocytic tumors, with focus on prognosis in nodular melanomas.
  • EXPERIMENTAL DESIGN: The immunohistochemical expression of E-cadherin, N-cadherin, P-cadherin, beta-catenin, and Wnt5a/Frizzled was examined using tissue microarrays of 312 melanocytic tumors.
  • Wnt5a and its receptor Frizzled were highly coexpressed, and nuclear expression of both markers was significantly reduced from benign nevi to melanomas, with a shift from nuclear to cytoplasmic expression in malignant tumors.
  • CONCLUSIONS: Alterations in the expression and subcellular localization of cell adhesion markers are important in the development and progression of melanocytic tumors, and strong cytoplasmic P-cadherin expression and loss of nuclear beta-catenin staining were associated with aggressive melanoma behavior and reduced patient survival.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Cadherins / metabolism. Melanoma / mortality. Proto-Oncogene Proteins / metabolism. Skin Neoplasms / mortality. Wnt Proteins / metabolism. beta Catenin / metabolism
  • [MeSH-minor] Cell Membrane / chemistry. Cell Membrane / metabolism. Cell Nucleus / chemistry. Cell Nucleus / metabolism. Cell Proliferation. Cytoplasm / chemistry. Cytoplasm / metabolism. Disease Progression. Down-Regulation. Frizzled Receptors. Humans. Immunohistochemistry. Melanocytes / pathology. Neovascularization, Pathologic / diagnosis. Neovascularization, Pathologic / pathology. Nevus / diagnosis. Nevus / pathology. Prognosis. Receptors, G-Protein-Coupled. Receptors, Neurotransmitter / analysis. Receptors, Neurotransmitter / metabolism. Up-Regulation

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  • (PMID = 16361544.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cadherins; 0 / FZD5 protein, human; 0 / Frizzled Receptors; 0 / Proto-Oncogene Proteins; 0 / Receptors, G-Protein-Coupled; 0 / Receptors, Neurotransmitter; 0 / WNT5A protein, human; 0 / Wnt Proteins; 0 / beta Catenin
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53. Makary R, Mohammadi A, Rosa M, Shuja S: Twin gestation with complete hydatidiform mole and a coexisting live fetus: case report and brief review of literature. Obstet Med; 2010 Mar;3(1):30-2
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  • [Title] Twin gestation with complete hydatidiform mole and a coexisting live fetus: case report and brief review of literature.
  • Complete hydatidiform (also referred to as hydatiform) mole with coexisting live fetus is an exceedingly rare event.
  • We report a case of a 19-year-old primigravida, at 25 weeks gestation with a complete hydatidiform mole and a coexisting live fetus.
  • A morphologically normal live female fetus and placenta were delivered without complications, along with a separate mass of complete mole.
  • Our case is a rare example of a twin gestation composed of a complete hydatidiform mole with a coexisting live fetus, and illustrates the associated spectrum of maternal complications that mandate close pre- and post-natal surveillance.

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  • (PMID = 27582837.001).
  • [ISSN] 1753-495X
  • [Journal-full-title] Obstetric medicine
  • [ISO-abbreviation] Obstet Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4989764
  • [Keywords] NOTNLM ; choriocarcinoma / complete hydatidiform mole / live fetus / twin gestation
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54. González-Vela MC, Val-Bernal JF, González-López MA, Belaustegui I, Fernández-Llaca JH: Proliferating trichilemmal cyst associated with an epidermal nevus. J Dermatol; 2008 Jan;35(1):52-4
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  • [Title] Proliferating trichilemmal cyst associated with an epidermal nevus.
  • [MeSH-major] Neoplasms, Adnexal and Skin Appendage / etiology. Nevus / complications. Skin / pathology. Skin Neoplasms / complications


55. Bhattacharjee S, Choi JS, Yang ST, Choi SB, Kim J, Ahn WS: Solvothermal synthesis of Fe-MOF-74 and its catalytic properties in phenol hydroxylation. J Nanosci Nanotechnol; 2010 Jan;10(1):135-41
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  • The effect of temperature, phenol/H2O2 mole ratio, catalyst quantity, and solvent on catalytic performance was discussed, and a reaction mechanism is proposed based upon the experimental results.

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  • (PMID = 20352823.001).
  • [ISSN] 1533-4880
  • [Journal-full-title] Journal of nanoscience and nanotechnology
  • [ISO-abbreviation] J Nanosci Nanotechnol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iron Compounds; 0 / Organometallic Compounds; 0 / Phenols; BBX060AN9V / Hydrogen Peroxide
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56. Glavatskiy KS, Bedeaux D: Nonequilibrium properties of a two-dimensionally isotropic interface in a two-phase mixture as described by the square gradient model. Phys Rev E Stat Nonlin Soft Matter Phys; 2008 Jun;77(6 Pt 1):061101
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  • Furthermore, we give numerically obtained profiles of the concentration, the mole fraction, and the temperature, which illustrate the solution for some special cases.

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  • [ErratumIn] Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jan;83(1 Pt 1):019902
  • [ErratumIn] Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Oct;82(4 Pt 2):049902
  • (PMID = 18643211.001).
  • [ISSN] 1539-3755
  • [Journal-full-title] Physical review. E, Statistical, nonlinear, and soft matter physics
  • [ISO-abbreviation] Phys Rev E Stat Nonlin Soft Matter Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Lehmler HJ, Bummer PM: Mixing behavior of 10-(perfluorohexyl)-decanol and DPPC. Colloids Surf B Biointerfaces; 2005 Aug;44(2-3):74-81
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  • The concentration dependence of the onset pressure of the liquid-expanded to liquid condensed phase transition of DPPC showed a slight change with increasing mole fraction on all four subphases.
  • The surface area-mole fraction diagrams of 10-(perfluorohexyl)-decanol and DPPC on water, sodium chloride and calcium chloride showed near ideal behavior with slight negative deviations at higher surface pressure.

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  • (PMID = 16024238.001).
  • [ISSN] 0927-7765
  • [Journal-full-title] Colloids and surfaces. B, Biointerfaces
  • [ISO-abbreviation] Colloids Surf B Biointerfaces
  • [Language] ENG
  • [Grant] United States / NIBIB NIH HHS / EB / R21 EB002748-01; United States / NIBIB NIH HHS / EB / EB02748; United States / NIBIB NIH HHS / EB / EB002748-02; United States / NIEHS NIH HHS / ES / K25 ES012475-01A1; United States / NIBIB NIH HHS / EB / R21 EB002748-02; United States / NIEHS NIH HHS / ES / K25 ES012475; United States / NIBIB NIH HHS / EB / R21 EB002748; United States / NIEHS NIH HHS / ES / ES12475; United States / NIBIB NIH HHS / EB / EB002748-01; United States / NIEHS NIH HHS / ES / ES012475-01A1
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / 10-(perfluorohexyl)decanol; 0 / Alcohols; 0 / Colloids; 0 / Fluorocarbons; 0 / Lipid Bilayers; 0 / Pulmonary Surfactants; 059QF0KO0R / Water; 2644-64-6 / 1,2-Dipalmitoylphosphatidylcholine; 451W47IQ8X / Sodium Chloride; M4I0D6VV5M / Calcium Chloride
  • [Other-IDs] NLM/ NIHMS71497; NLM/ PMC2577365
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58. Navas M, Pascual JM, Fraga J, Pedrosa M, Shakur S, Carrasco R, Martínez P, Manzanares R, de Sola RG: Intracranial intermediate-grade meningeal melanocytoma with increased cellular proliferative index: an illustrative case associated with a nevus of Ota. J Neurooncol; 2009 Oct;95(1):105-115
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  • [Title] Intracranial intermediate-grade meningeal melanocytoma with increased cellular proliferative index: an illustrative case associated with a nevus of Ota.
  • Solitary primary melanocytic tumors of the central nervous system (CNS) represent a spectrum of lesions ranging from well-differentiated melanocytoma to melanoma.
  • The association of a meningeal melanocytoma with an ipsilateral nevus of Ota is extremely rare, with only six cases reported in the literature to date.
  • Only a minority of melanocytic tumors correspond to lesions of intermediate-grade malignancy, whose biological behavior and outcome remain undetermined.
  • We report a new case of a 25-year-old man with a giant fronto-temporal intracranial meningeal melanocytoma associated with a congenital nevus of Ota, who suffered an acute neurological deterioration requiring an emergent surgical procedure.
  • The lesion showed no histological criteria of malignancy but did exhibit an elevated (8%) MIB-1/Ki-67 cell proliferative index, which suggested an intermediate-grade melanocytoma.
  • To our knowledge, this is the first case of a meningeal melanocytoma of intermediate grade associated with a nevus of Ota reported in the literature.
  • The MIB-1/Ki-67 labeling index may have potential prognostic value in helping the clinician to predict an aggressive clinical behavior and/or malignant progression for primary melanocytic neoplasms of the CNS.
  • [MeSH-major] Melanoma / pathology. Meningeal Neoplasms / pathology. Nevus of Ota / pathology
  • [MeSH-minor] Adult. Humans. Male. Nevus, Pigmented / surgery. Radiography. Tomography Scanners, X-Ray Computed

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  • (PMID = 19449182.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Petros HM: What's your assessment? Blue rubber bleb nevus syndrome. Dermatol Nurs; 2007 Oct;19(5):465-7
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  • [Title] What's your assessment? Blue rubber bleb nevus syndrome.

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  • (PMID = 18286860.001).
  • [ISSN] 1060-3441
  • [Journal-full-title] Dermatology nursing
  • [ISO-abbreviation] Dermatol Nurs
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. de Maleissye MF, Beauchet A, Aegerter P, Saiag P, Mahé E: Parents' attitudes related to melanocytic nevus count in children. Eur J Cancer Prev; 2010 Nov;19(6):472-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parents' attitudes related to melanocytic nevus count in children.
  • Sun exposure, fair phototype, and a high common melanocytic nevus (MN) count have been identified as the most important risk factors for melanoma.
  • MN are mainly acquired during childhood, and their relationship to sun exposure, sunburn, and light skin complexion is well documented.
  • Multivariate analysis showed that the childhood MN count was linked to fair phenotype--fair skin: rate ratio (RR)=3.80, 95% confidence interval (CI)=2.25-6.41; blue/green eyes: RR=1.2, 95% CI=1.11-1.34; blond hair: RR=1.25, 95% CI=1.10-1.41; history of sunburn: RR=1.13, 95% CI=1.03-1.23, seaside sun exposure--RR=1.14, 95% CI=1.01-1.28, and to their parents' behaviors during exposure to the sun--increase in the number of MN when parents used sunscreen: RR=1.23, 95% CI=1.08-1.40; decrease in MN count when parents wore a tee-shirt: RR=0.86, 95% CI=0.79-0.93.
  • [MeSH-major] Attitude to Health. Melanoma / prevention & control. Nevus, Pigmented / prevention & control. Skin Neoplasms / prevention & control

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  • (PMID = 20736840.001).
  • [ISSN] 1473-5709
  • [Journal-full-title] European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
  • [ISO-abbreviation] Eur. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sunscreening Agents
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61. Triki S, Mekni A, Haouet S, Mokni M, Kchir N, Ben Osman Dhahri A, Zitouna M: [Nevus lipomatosus cutaneous superficialis: a clinico-pathological study of 13 cases]. Tunis Med; 2006 Dec;84(12):800-2
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  • [Title] [Nevus lipomatosus cutaneous superficialis: a clinico-pathological study of 13 cases].
  • [Transliterated title] Naevus lipomateux cutane superficiel : étude anatomoclinique de 13 cas.
  • Nevus lipomatosus cutaneous superficialis (NLCS) is a rare hamartomatous skin lesion histologically characterised by the presence of mature fat tissue within the dermis.
  • [MeSH-major] Nevus / pathology. Skin Neoplasms / pathology

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  • (PMID = 17288284.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Tunisia
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62. Taube JM, Begum S, Shi C, Eshleman JR, Westra WH: Benign nodal nevi frequently harbor the activating V600E BRAF mutation. Am J Surg Pathol; 2009 Apr;33(4):568-71
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  • [Title] Benign nodal nevi frequently harbor the activating V600E BRAF mutation.
  • Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
  • Potentially, BRAF mutation analysis of sentinel lymph node (SLN) biopsies could enhance the detection of micrometastases and improve the accuracy of nodal staging for patients with melanoma.
  • Nodal nevi are small aggregates of benign nevus cells that are commonly encountered in the SLNs of patients with melanoma.
  • The status of the BRAF gene in nodal nevi is not known, but this unresolved issue is of critical importance to any future detection strategies that use genetic alterations as biomarkers of metastatic spread.
  • Twenty-six nodal nevi from 26 patients were evaluated for the thymine (T)-->adenine (A) missense mutation at nucleotide 1796 of the BRAF gene using the LigAmp assay, which can detect 1 mutant allele among 10,000 wild-type alleles.
  • BRAF mutations were detected in 13 of the 26 nodal nevi, but in just 1 of the 26 adjacent controls (50% vs. 4%, P<0.0005, Fisher exact).
  • Novel strategies that rely on detection of putative melanoma-specific markers for the diagnosis of micrometastatic melanoma in SLNs need to take into account the molecular genetic profile of the benign nodal nevus.
  • Indeed, these nodal nevi, like melanoma, frequently harbor activating mutations of the BRAF oncogene underscoring the potentially confounding impact of these inclusions on melanoma detection.
  • [MeSH-major] Lymph Nodes / pathology. Melanoma / diagnosis. Mutation, Missense. Nevus / diagnosis. Proto-Oncogene Proteins B-raf / genetics. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. DNA Mutational Analysis. DNA, Neoplasm / analysis. Female. Humans. Male. Middle Aged. Young Adult


63. Mason MJ: Evolution of the middle ear apparatus in Talpid moles. J Morphol; 2006 Jun;267(6):678-95
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  • [Title] Evolution of the middle ear apparatus in Talpid moles.
  • The middle ear structures of eight species of mole in the family Talpidae (Mammalia: Eulipotyphla) were studied under light and electron microscopy.
  • These characteristics are ancestral for talpid moles.
  • By contrast, the unusual middle ear apparatus of Parascaptor, which exhibits striking similarities to that of golden moles, probably augments seismic sensitivity by inertial bone conduction.
  • [MeSH-major] Ear, Middle / anatomy & histology. Moles / anatomy & histology

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  • [Copyright] J. Morphol. (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16511863.001).
  • [ISSN] 0362-2525
  • [Journal-full-title] Journal of morphology
  • [ISO-abbreviation] J. Morphol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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64. Yap FB: Nevus lipomatosus superficialis. Singapore Med J; 2009 May;50(5):e161-2
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  • [Title] Nevus lipomatosus superficialis.
  • Nevus lipomatosus superficialis is a rare benign skin malformation characterised by ectopic adipocytes in the upper dermis.
  • A case of the classical type with multiple soft, non-tender, pedunculated, cerebriform, skin-coloured papules and nodules over the right lower back is presented in a 21-year-old Malay woman.
  • [MeSH-minor] Adipocytes / pathology. Adult. Female. Humans. Nevus, Pigmented / diagnosis. Nevus, Pigmented / pathology. Nevus, Pigmented / surgery. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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  • (PMID = 19495497.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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65. Hofmann UB, Bröcker EB, Hamm H: Simultaneous onset of segmental vitiligo and a halo surrounding a congenital melanocytic naevus. Acta Derm Venereol; 2009;89(4):402-6
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  • [Title] Simultaneous onset of segmental vitiligo and a halo surrounding a congenital melanocytic naevus.
  • Unlike in common melanocytic naevi, an acquired leukoderma (halo) surrounding a congenital melanocytic naevus is a rare phenomenon.
  • A 6-year-old boy developed a depigmentation around a congenital melanocytic naevus on the right thigh.
  • The simultaneous occurrence of a halo phenomenon around a congenital melanocytic naevus and segmental vitiligo, as well as identical histological and immunohistological findings in both pigmented lesions, suggest shared immunological mechanisms.
  • [MeSH-major] Nevus, Pigmented / immunology. Skin Neoplasms / immunology. Skin Pigmentation / immunology. Vitiligo / immunology
  • [MeSH-minor] Antigens, Neoplasm / metabolism. Child. Dermis / metabolism. Humans. Immunohistochemistry. MART-1 Antigen. Male. Melanocytes / metabolism. Melanocytes / pathology. Neoplasm Proteins / metabolism. T-Lymphocytes, Cytotoxic / metabolism

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  • (PMID = 19688155.001).
  • [ISSN] 1651-2057
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins
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66. Woan K, Tsai YY, Sigmund W: Synthesis and characterization of luminescent cerium oxide nanoparticles. Nanomedicine (Lond); 2010 Feb;5(2):233-42
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  • RESULTS: The nanoparticles exhibited enhancement of the catalytic properties with increasing erbium content to 10 mole% in the cerium oxide lattice; and they demonstrated emission at 515 nm and 572.5 nm under 405 nm UV excitation in aqueous conditions.

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  • (PMID = 20148635.001).
  • [ISSN] 1748-6963
  • [Journal-full-title] Nanomedicine (London, England)
  • [ISO-abbreviation] Nanomedicine (Lond)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Surface-Active Agents; 30K4522N6T / Cerium; 619G5K328Y / ceric oxide; 77B218D3YE / Erbium; BBX060AN9V / Hydrogen Peroxide
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67. Yan CY, Ma WL, Yan WW, Yu RM: [Biotransformation of furannoligularenone by hairy root cultures of Polygonum multiflorum]. Zhong Yao Cai; 2008 May;31(5):633-5
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  • After co-cultured for 3 days, the mole conversion ratio of the substrate reached the highest (27.2%).

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  • (PMID = 18826134.001).
  • [ISSN] 1001-4454
  • [Journal-full-title] Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  • [ISO-abbreviation] Zhong Yao Cai
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Culture Media; 0 / Furans; 0 / Sesquiterpenes; 0 / furannoligularenone
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68. Jiang BG, Zhang L, Fan SD: [The spectrum studies of mechano-optical signal transduction with participation of LDH]. Guang Pu Xue Yu Guang Pu Fen Xi; 2008 Mar;28(3):609-11
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  • : NADH was 1 : 4.5 (mole ratio)without lactate, and the average period of system was shortened from 108 to 34 min, and to 29 min with lactate existing.

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  • (PMID = 18536424.001).
  • [ISSN] 1000-0593
  • [Journal-full-title] Guang pu xue yu guang pu fen xi = Guang pu
  • [ISO-abbreviation] Guang Pu Xue Yu Guang Pu Fen Xi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0U46U6E8UK / NAD; EC 1.1.1.27 / L-Lactate Dehydrogenase
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69. Cutts SM, Nudelman A, Pillay V, Spencer DM, Levovich I, Rephaeli A, Phillips DR: Formaldehyde-releasing prodrugs in combination with adriamycin can overcome cellular drug resistance. Oncol Res; 2005;15(4):199-213
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  • Drugs that released two molar equivalents of formaldehyde per mole of prodrug were superior in their ability to enhance adduct formation compared to those that released one molar equivalent.
  • However, in growth inhibition experiments, prodrug combinations were able to overcome Adriamycin resistance to varying degrees, and the combination of Adriamycin with selected prodrugs that release two moles of formaldehyde totally overcame resistance in HL60/MX2 cells.
  • Combinations of Adriamycin with selected prodrugs that release one or two moles of formaldehyde partially overcame P-glycoprotein-mediated resistance in MES-SA/Dx5 cells.
  • [MeSH-major] Antineoplastic Agents / pharmacology. Butyrates / pharmacology. DNA Adducts / pharmacology. Doxorubicin / pharmacology. Drug Resistance, Neoplasm / drug effects. Formaldehyde / pharmacology. Prodrugs / pharmacology

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  • (PMID = 17822280.001).
  • [ISSN] 0965-0407
  • [Journal-full-title] Oncology research
  • [ISO-abbreviation] Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Butyrates; 0 / DNA Adducts; 0 / Prodrugs; 0 / Topoisomerase II Inhibitors; 0 / doxorubicin-DNA; 122110-53-6 / pivalyloxymethyl butyrate; 1HG84L3525 / Formaldehyde; 80168379AG / Doxorubicin
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70. Newman MD, Lertsburapa T, Mirzabeigi M, Mafee M, Guitart J, Gerami P: Fluorescence in situ hybridization as a tool for microstaging in malignant melanoma. Mod Pathol; 2009 Aug;22(8):989-95
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  • [Title] Fluorescence in situ hybridization as a tool for microstaging in malignant melanoma.
  • Up to 30-50% of melanomas arise in association with a nevus.
  • Accurately defining, the nevus from the melanoma can significantly affect microstaging.
  • Recently, we showed that a targeted fluorescence in situ hybridization (FISH) assay could distinguish between benign nevi and melanoma with a sensitivity of 87% and specificity of 95%.
  • In this study, we evaluated the potential of this same assay for use in the microstaging of melanoma.
  • We performed FISH on 36 cases of melanoma occurring in association with a nevus and 6 cases of nevoid melanoma with deep dermal involvement.
  • In the melanomas with associated benign nevi, FISH enumeration was performed separately on the histologically malignant and benign components.
  • On the basis of the criteria developed in our earlier studies, we determined the sensitivity of the assay within the malignant areas and the specificity within the benign areas of melanomas with associated nevi.
  • Among melanomas with associated nevi, 28 of 36 cases (78%) tested positively in the histologically malignant areas.
  • The benign nevus components were uniformly negative for all criteria.
  • FISH analysis with probes targeting 6p25, 6q23, 11q13 and CEP6 can effectively discriminate the malignant and benign components of melanomas with associated nevi and can be used as an adjunctive tool for microstaging.
  • The assay has high sensitivity for the malignant areas of nevus-associated melanomas and outstanding specificity for the benign areas.
  • The sensitivity is independent of the morphological features, and the assay performs well in nevoid melanoma cases.
  • [MeSH-major] In Situ Hybridization, Fluorescence. Melanoma / pathology. Neoplasm Staging / methods. Nevus, Pigmented / pathology. Skin Neoplasms / pathology

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  • (PMID = 19448594.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Da Forno PD, Fletcher A, Pringle JH, Saldanha GS: Understanding spitzoid tumours: new insights from molecular pathology. Br J Dermatol; 2008 Jan;158(1):4-14
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  • Spitzoid tumours are a morphologically diverse group of lesions that share histological similarity to the Spitz naevus, a benign melanocytic skin tumour.
  • Distinguishing classic Spitz naevi from cutaneous malignant melanoma is usually achievable on standard histology sections, but occasionally equivocal lesions are encountered that show features intermediate between these two entities and consequently generate considerable clinical and histopathological concern.
  • These studies compare spitzoid tumours with better-characterized melanocytic lesions, and from such comparisons assumptions concerning the biological nature of different spitzoid tumours can be made.
  • In contrast, investigations of the mitogen-activated protein kinase (MAPK) pathway and DNA gains and losses have suggested that Spitz naevi may be genetically distinct from other melanocytic tumours.
  • [MeSH-major] Nevus, Epithelioid and Spindle Cell / genetics. Skin Neoplasms / genetics
  • [MeSH-minor] Diagnosis, Differential. Disease Progression. Humans. MAP Kinase Signaling System / genetics. Melanoma / diagnosis. Melanoma / genetics


72. Atassi MZ, Childress C: Oxygen-binding heme complexes of peptides designed to mimic the heme environment of myoglobin and hemoglobin. Protein J; 2005 Jan;24(1):37-49
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  • However, each of the peptides that were designed to mimic the E-F helices, and even shorter designs, which removed from this region residues that do not contribute to contacts with the heme group, were each able to bind one mole of heme per mole of peptide forming peptide heme complexes that were stable to manipulation and behaved as single molecular species.

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  • (PMID = 15756816.001).
  • [ISSN] 1572-3887
  • [Journal-full-title] The protein journal
  • [ISO-abbreviation] Protein J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Hemoglobins; 0 / Macromolecular Substances; 0 / Myoglobin; 0 / Peptides; 42VZT0U6YR / Heme; S88TT14065 / Oxygen
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73. Eichhorn R, Wessler G, Scholz M, Leupold D, Stankovic G, Buder S, Stücker M, Hoffmann K: Early diagnosis of melanotic melanoma based on laser-induced melanin fluorescence. J Biomed Opt; 2009 May-Jun;14(3):034033
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  • [Title] Early diagnosis of melanotic melanoma based on laser-induced melanin fluorescence.
  • Because of the increasing incidence of skin cancer, interest in using the autofluorescence of skin tissue as a noninvasive tool for early diagnosis is enforced.
  • Focus is especially on malignant melanotic melanoma.
  • On the basis of a newly developed method to selectively excite melanin fluorescence of skin tissue by stepwise two-photon excitation with nanosecond laser pulses at 810 nm, we have investigated information from this melanin fluorescence with respect to the differentiation of pigmented lesions.
  • A distinct difference in the melanin fluorescence spectrum of malignant melanoma (including melanoma in situ) when compared to that of benign melanocytic lesions (i.e., common nevi) has been found for freshly excised samples as well as for histopathological samples.
  • There is also specific fluorescence from dysplastic nevi.
  • In this way, early detection of malignant melanoma is possible.
  • [MeSH-major] Lasers. Melanins / chemistry. Melanoma / diagnosis. Skin Neoplasms / diagnosis. Spectrometry, Fluorescence / methods
  • [MeSH-minor] Dysplastic Nevus Syndrome / diagnosis. Equipment Design. Flavin-Adenine Dinucleotide / chemistry. Histocytochemistry. Humans. Skin / chemistry

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  • (PMID = 19566326.001).
  • [ISSN] 1083-3668
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Melanins; 146-14-5 / Flavin-Adenine Dinucleotide
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74. Mazoit JX, Le Guen R, Beloeil H, Benhamou D: Binding of long-lasting local anesthetics to lipid emulsions. Anesthesiology; 2009 Feb;110(2):380-6
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  • RESULTS: The apparent distribution coefficient expressed as the ratio of mole fraction was 823 +/- 198 and 320 +/- 65 for racemic bupivacaine and levobupivacaine, and ropivacaine, respectively, at 500 mg in the Medialipide/buffer emulsion; and 1,870 +/- 92 and 1,240 +/- 14 for racemic bupivacaine and levobupivacaine, and ropivacaine, respectively, in the Intralipid/buffer emulsion.

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  • (PMID = 19194164.001).
  • [ISSN] 1528-1175
  • [Journal-full-title] Anesthesiology
  • [ISO-abbreviation] Anesthesiology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amides; 0 / Anesthetics, Local; 0 / Buffers; 0 / Fat Emulsions, Intravenous; 0 / Triglycerides; 7IO5LYA57N / ropivacaine; Y8335394RO / Bupivacaine
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75. Liu YB, Fan JC, Jiao P, Tang X, Liu LQ, Wang Q, Tian J, Gan C, Yang ZJ, Zhang ZN, Chen YG: [Repair of the facial defects using the expanded induced prefabricated skin flap of the retroauricular and mastoid process region based on the superficial temporal vascular bundle]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2007 May;23(3):187-90
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  • [Title] [Repair of the facial defects using the expanded induced prefabricated skin flap of the retroauricular and mastoid process region based on the superficial temporal vascular bundle].
  • When the expanding process has been finished, the expander was removed and the expanded induced prefabricated skin flap of the retroauricular and mastoid process region pedicled on the superficial temporal vascular bundle was elevated and transferred to repair the facial skin defect.
  • Facial defects after resection of the melanotic nevus was repaired in 2 cases and facial defects after resection of the facial haemangioma and scar were repaired in 2 and 5 cases respectively.
  • The size of the prefabricated skin flaps was ranged from 5 cm x 5 cm to 8.0 cm x 7.5 cm (mean size 6.4 cm x 6.1 cm).
  • The split-thickness skin grafting was used to recover the donor site defects in 4 cases.
  • Meanwhile, the skin of the retroauricular and mastoid process region is most similar to that of the face in texture, color and depth.
  • [MeSH-major] Ear, External / surgery. Facial Injuries / surgery. Skin Transplantation / methods. Soft Tissue Injuries / surgery

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  • (PMID = 17649933.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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76. Klatt TE, Franciosi RA, Cruikshank DP: Normal fetus with a twin presenting as both a complete hydatidiform mole and placenta previa. Obstet Gynecol; 2006 Feb;107(2 Pt 2):527-30
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  • [Title] Normal fetus with a twin presenting as both a complete hydatidiform mole and placenta previa.
  • BACKGROUND: A twin gestation comprising a complete hydatidiform mole and a coexisting normal fetus is a rare and high-risk condition.
  • CONCLUSION: We recommend that intra-arterial balloon catheters be considered before cesarean delivery in cases of complete hydatidiform mole with a coexisting normal fetus if the molar pregnancy presents as a previa.
  • [MeSH-major] Hydatidiform Mole / complications. Placenta Previa. Twins. Uterine Neoplasms / complications

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  • (PMID = 16449175.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Zajac M, Jelińska A, Sobczak A, Musiał W: Stability of ceftazidime pentahydrate in medicinal preparations Biotum and Ceftim. Acta Pol Pharm; 2005 Jan-Feb;62(1):11-5
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  • The study was conducted using the HPLC method on LiChrosorb RP-18 columns (250 x 4 mm) with 9% acetonitrile in 0.1 mole/L ammonium acetate as mobile phase and detection at 254 nm.

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  • (PMID = 16022488.001).
  • [ISSN] 0001-6837
  • [Journal-full-title] Acta poloniae pharmaceutica
  • [ISO-abbreviation] Acta Pol Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Cephalosporins; 0 / Indicators and Reagents; 9M416Z9QNR / Ceftazidime
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78. Katunarić M, Jurisić D, Hadzisejdić I, Kirin I, Zamolo G: Real-time expression of hTERT in primary melanoma biopsies. Coll Antropol; 2010 Dec;34(4):1401-4
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  • [Title] Real-time expression of hTERT in primary melanoma biopsies.
  • Skin melanoma is by far the most lethal skin cancer, it is unpredictable by nature and presents a severe diagnostic problem.
  • One of the major issues in melanoma diagnostics is to differentiate it with confidence from a dysplastic nevus.
  • Thus, the aim of this study was to evaluate hTERT expression on a spectrum of dermal lesions (from normal skin toprimary melanoma) in order to examine its possible role as a diagnostic marker in melanoma diagnostics.
  • In this study we analyzed the expression of hTERT by real-time PCR on 58 freshly obtained biopsy samples (4 samples of normal skin, 12 dermal nevi, 23 dysplastic nevi, 19 primary melanomas).
  • Our results showed slightly greater hTERT expression in dysplastic nevi than melanomas with major data overlap.
  • Considering the given results, hTERT does not seem to be a reliable diagnostic marker for melanoma.
  • [MeSH-major] Melanoma / genetics. Skin Neoplasms / genetics. Telomerase / genetics

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  • (PMID = 21874728.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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79. Santillan AA, Cherpelis BS, Glass LF, Sondak VK: Management of familial melanoma and nonmelanoma skin cancer syndromes. Surg Oncol Clin N Am; 2009 Jan;18(1):73-98, viii
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  • [Title] Management of familial melanoma and nonmelanoma skin cancer syndromes.
  • The clinical manifestations of hereditary skin cancer syndromes depend upon the interplay between environmental and genetic factors.
  • Familial melanoma occurs in the setting of hereditary susceptibility, with a complex phenotype of early age of onset, multiple atypical moles, multiple primary melanomas, multiple melanomas in the family, and in some instances pancreatic cancer.
  • Identification of individuals who may have a hereditary susceptibility for the development of melanoma is essential to provide an opportunity for primary prevention, and to target high-risk groups for early diagnosis and treatment.
  • Consequently, the surgeon as one of the primary caregivers should be familiar with hereditary skin cancer syndromes and their pathogenesis, diagnosis, management, and surveillance recommendations.
  • This article discusses a practical approach for some of the issues likely encountered by the surgeon in the management of familial melanoma and non-melanoma skin cancer.
  • [MeSH-major] Melanoma / genetics. Melanoma / therapy. Neoplastic Syndromes, Hereditary / therapy. Skin Neoplasms / genetics. Skin Neoplasms / therapy

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  • (PMID = 19056043.001).
  • [ISSN] 1055-3207
  • [Journal-full-title] Surgical oncology clinics of North America
  • [ISO-abbreviation] Surg. Oncol. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 135
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80. Che L, Ren Z, Wang X, Dong W, Dai D, Wang X, Zhang DH, Yang X, Sheng L, Li G, Werner HJ, Lique F, Alexander MH: Breakdown of the Born-Oppenheimer approximation in the F+ o-D2 -&gt; DF + D reaction. Science; 2007 Aug 24;317(5841):1061-4
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  • In a crossed-beam scattering experiment, we determined relative integral and differential cross sections for reaction of the ground F(2P(3/2)) and excited F*(2P(1/2)) spin-orbit states with D2 for collision energies of 0.25 to 1.2 kilocalorie/mole.

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  • (PMID = 17717180.001).
  • [ISSN] 1095-9203
  • [Journal-full-title] Science (New York, N.Y.)
  • [ISO-abbreviation] Science
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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81. Alcântara EF, Faria EA, Rodrigues DV, Evangelista SM, DeOliveira E, Zara LF, Rabelo D, Prado AG: Modification of silica gel by attachment of 2-mercaptobenzimidazole for use in removing Hg(II) from aqueous media: a thermodynamic approach. J Colloid Interface Sci; 2007 Jul 1;311(1):1-7
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  • The maximum number of moles adsorbed was determined to be 1.35+/-0.3 and 1.42+/-0.17 mmolg-1 for SiMhet and SiMhomt, respectively.

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  • (PMID = 17416385.001).
  • [ISSN] 0021-9797
  • [Journal-full-title] Journal of colloid and interface science
  • [ISO-abbreviation] J Colloid Interface Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzimidazoles; 0 / Gels; 059QF0KO0R / Water; 619CVM6HOK / 2-mercaptobenzimidazole; 7631-86-9 / Silicon Dioxide; FXS1BY2PGL / Mercury
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82. Ko JM, Velez NF, Tsao H: Pathways to melanoma. Semin Cutan Med Surg; 2010 Dec;29(4):210-7
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  • [Title] Pathways to melanoma.
  • Melanoma is one of the most aggressive and yet poorly understood of human malignancies.
  • Advances in genomics has allowed a more nuanced understanding of the disease, moving beyond the traditional dysplastic nevus-to-melanoma model and identifying multiple divergent oncogenic pathways leading to melanoma.
  • An understanding of the molecular mechanisms driving melanoma has opened the doors for the development of targeted therapeutic approaches.
  • As we enter the era of personalized medicine, it will be critical for clinicians to both appreciate and be able to determine the molecular profile of their patients' melanoma because this profile will guide risk stratification, genetic counseling, and treatment customization.
  • A review of the divergent pathways of melanoma development is presented here, with a particular emphasis on recently identified mutations, and their implications for patient care.
  • [MeSH-major] Melanoma / genetics. Oncogenes. Skin Neoplasms / genetics
  • [MeSH-minor] Cell Transformation, Neoplastic. Humans. Nevus / genetics. Nevus / pathology

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  • [Copyright] Copyright © 2010. Published by Elsevier Inc.
  • (PMID = 21277534.001).
  • [ISSN] 1558-0768
  • [Journal-full-title] Seminars in cutaneous medicine and surgery
  • [ISO-abbreviation] Semin Cutan Med Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
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83. Moutray T, Napier M, Shafiq A, Fryer A, Rankin S, Willoughby CE: Monozygotic twins discordant for phacomatosis pigmentovascularis: evidence for the concept of twin spotting. Am J Med Genet A; 2010 Mar;152A(3):718-20
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  • The term phacomatosis pigmentovascularis (PPV) refers to the occurrence of vascular nevi with melanocytic or epidermal nevi.
  • The affected twin had a nevus flammeus on the right arm and the right maxilla, and a pigmented area on the trunk in keeping with a persistent, aberrant Mongolian spot.

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  • [Copyright] (c) 2010 Wiley-Liss, Inc.
  • (PMID = 20186807.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Freire MG, Carvalho PJ, Fernandes AM, Marrucho IM, Queimada AJ, Coutinho JA: Surface tensions of imidazolium based ionic liquids: anion, cation, temperature and water effect. J Colloid Interface Sci; 2007 Oct 15;314(2):621-30
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  • The influence of water content in the surface tension was studied for several ILs as a function of the temperature as well as a function of water mole fraction, for the most hydrophobic IL investigated, [omim][PF(6)], and one of the more hygroscopic IL, [bmim][PF(6)].

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  • (PMID = 17604038.001).
  • [ISSN] 0021-9797
  • [Journal-full-title] Journal of colloid and interface science
  • [ISO-abbreviation] J Colloid Interface Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Khalifeh I, Taraif S, Reed JA, Lazar AF, Diwan AH, Prieto VG: A subgroup of melanocytic nevi on the distal lower extremity (ankle) shares features of acral nevi, dysplastic nevi, and melanoma in situ: a potential misdiagnosis of melanoma in situ. Am J Surg Pathol; 2007 Jul;31(7):1130-6
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  • [Title] A subgroup of melanocytic nevi on the distal lower extremity (ankle) shares features of acral nevi, dysplastic nevi, and melanoma in situ: a potential misdiagnosis of melanoma in situ.
  • Melanocytic lesions in certain locations (eg, genital, breast, acral) may have histologic and clinical features simulating melanoma.
  • Here we describe a group of lesions from the lower distal extremity and analyze their histologic features and possible relation to dysplastic nevi (DN) and melanomas.
  • One hundred fifteen melanocytic lesions from the ankle were retrieved from January 1990 to August 2006 from the files of M. D.
  • Anderson Cancer Center and were classified as benign melanocytic nevi (BN; n=17), DN (n=35), melanomas (MM; n=52), and melanocytic nevi of the ankle with atypical features (MNAAF; ie, cases that did not readily fit in any of the previous categories, n=11).
  • All MNAAF showed moderate-severe architectural disorder whereas 78% showed only mild-moderate cytologic atypia.
  • This study highlights a group of melanocytic lesions located on the ankle that share histologic features with acral nevi, DN, and melanoma.
  • After complete excision, follow-up data indicate an apparently benign outcome.
  • Pathologists should be aware of this type of lesions to avoid overdiagnosis of melanoma.
  • [MeSH-major] Diagnostic Errors / prevention & control. Dysplastic Nevus Syndrome / pathology. Hutchinson's Melanotic Freckle / pathology. Nevus, Pigmented / pathology. Precancerous Conditions / pathology. Skin Neoplasms / pathology

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  • (PMID = 17592281.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Melanins
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86. Magnúsdóttir V, Stefánsson E: [Choroidal haemangioma worsens after laser therapy for skin port-wine nevus and improves with photodynamic therapy in the eye]. Laeknabladid; 2007 Feb;93(2):119-21
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  • [Title] [Choroidal haemangioma worsens after laser therapy for skin port-wine nevus and improves with photodynamic therapy in the eye].
  • A young man with facial port-wine nevus on one side of his face underwent skin laser treatment on his facial lesions and experienced worsening visual acuity from 0.9 to 0.4 and metamorphosis afterwards in the ipsilateral eye.


87. Chiu GN, Abraham SA, Ickenstein LM, Ng R, Karlsson G, Edwards K, Wasan EK, Bally MB: Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese. J Control Release; 2005 May 18;104(2):271-88
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  • In the present study, doxorubicin was encapsulated into two thermosensitive liposome formulations which were composed of DPPC/MSPC/DSPE-PEG(2000) (90/10/4 mole ratio) or DPPC/DSPE-PEG(2000) (95/5 mole ratio).

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  • (PMID = 15907579.001).
  • [ISSN] 0168-3659
  • [Journal-full-title] Journal of controlled release : official journal of the Controlled Release Society
  • [ISO-abbreviation] J Control Release
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Drug Carriers; 0 / Liposomes; 37H9VM9WZL / Calcimycin; 42Z2K6ZL8P / Manganese; 80168379AG / Doxorubicin
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88. Mobio S, Noujeim Z, Boutigny H, Jensen M, Cassia A, Soueidan A: [Pigmentation and pigmented lesions of the gingival mucosa]. Rev Belge Med Dent (1984); 2008;63(1):15-28
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  • When melanocytes are directly concerned, the lesions can be of intrinsic origin, such as oral mucosa melanoma, the nevus, pigmented oral lichen planus etc.
  • In this article, gingival pigmentations are described to allow practitioner to elaborate a differential and positive diagnosis of gingival pigmented lesions and to facilitate an early detection of these lesions particularly the gingival melanoma.
  • [MeSH-minor] Diagnosis, Differential. Gingival Neoplasms / diagnosis. Humans. Melanoma / diagnosis. Nevus / diagnosis

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  • (PMID = 18754536.001).
  • [ISSN] 0775-0293
  • [Journal-full-title] Revue belge de médecine dentaire
  • [ISO-abbreviation] Rev Belge Med Dent (1984)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 89
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89. Hansen N, Kasper T, Klippenstein SJ, Westmoreland PR, Law ME, Taatjes CA, Kohse-Höinghaus K, Wang J, Cool TA: Initial steps of aromatic ring formation in a laminar premixed fuel-rich cyclopentene flame. J Phys Chem A; 2007 May 17;111(19):4081-92
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  • Mole fractions as a function of distance from the burner are measured for 49 intermediates with ion masses ranging from 2 (H2) to 106 (C8H10), providing a broad database for flame modeling studies.

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  • (PMID = 17300183.001).
  • [ISSN] 1089-5639
  • [Journal-full-title] The journal of physical chemistry. A
  • [ISO-abbreviation] J Phys Chem A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Amato C, Elia M, Schepis C: Schimmelpenning syndrome: a kind of craniofacial epidermal nevus associated with cerebral and ocular MR imaging abnormalities. AJNR Am J Neuroradiol; 2010 May;31(5):E47-8
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  • [Title] Schimmelpenning syndrome: a kind of craniofacial epidermal nevus associated with cerebral and ocular MR imaging abnormalities.
  • [MeSH-major] Brain / abnormalities. Brain / pathology. Eye Abnormalities / diagnosis. Facial Dermatoses / diagnosis. Nevus / diagnosis


91. Mulekar SV, Issa AA, Eisa AA: Treatment of halo nevus with a 308-nm excimer laser: a pilot study. J Cosmet Laser Ther; 2007 Dec;9(4):245-8
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  • [Title] Treatment of halo nevus with a 308-nm excimer laser: a pilot study.
  • BACKGROUND: The treatment of halo nevus is controversial and ranges from observation requiring no therapy to excision biopsy.
  • OBJECTIVE: To assess the efficacy of excimer laser for the treatment of halo nevus.
  • METHODS: Four patients with halo nevus on the face were treated by excimer laser three times a week until they achieved 75% pigmentation or a maximum of 36 treatment sessions.
  • CONCLUSION: Treatment with the 308-nm excimer laser may be an effective treatment of halo nevi located on the face.
  • [MeSH-major] Facial Neoplasms / radiotherapy. Lasers, Excimer / therapeutic use. Low-Level Light Therapy / methods. Nevus, Pigmented / radiotherapy

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  • [CommentIn] J Cosmet Laser Ther. 2008 Dec;10(4):217 [18618360.001]
  • (PMID = 18236244.001).
  • [ISSN] 1476-4172
  • [Journal-full-title] Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology
  • [ISO-abbreviation] J Cosmet Laser Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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92. Anbalagan K, Lydia IS: Homogeneous solvation controlled photoreduction of cobalt(III) complexes in aqueous 2-methyl-2-propanol solutions linear solvation energy relationship and cyclic voltammetric analyses. Spectrochim Acta A Mol Biomol Spectrosc; 2008 Mar;69(3):964-70
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  • Irradiation of the complexes with UV light (lambda=254nm) in binary mixtures produce Co(II)(aq) and the concentration of this species are highly dependent on x(alc) (x(alc)=mole fraction of alcohol).
  • The observed quantum yield (logPhi(Co(II))) is found to be linearly related to mole fraction of organic co-solvent added in the mixture, therefore, logPhi(Co(II))=26.41 x 10(-2) when x(2)=0.0094 and 43.75 x 10(-2) when x(2)=0.076 for a typical complex Co(III)(en)(2)Br(p-OCH(3)C(6)H(4)NH(2))(2+) in aqueous 2-methyl-2-propanol at 300K.

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  • (PMID = 17698408.001).
  • [ISSN] 1386-1425
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Solutions; 0 / Solvents; 3G0H8C9362 / Cobalt; 96F264O9SV / 1-Propanol
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93. Losada-Pérez P, Pérez-Sánchez G, Troncoso J, Cerdeiriña CA: Heat capacity anomalies along the critical isotherm in fluid-fluid phase transitions. J Chem Phys; 2010 Apr 21;132(15):154509
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  • From the complete scaling formulation of fluid-fluid criticality, explicit expressions for the critical amplitudes of the leading /Y-Y(c)/(-alpha/beta) (where Y can be the density or the mole fraction) contributions are found to reveal previously discovered features of the scaling function, whereas the nature of the most important asymmetry-related terms is characterized.

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  • (PMID = 20423191.001).
  • [ISSN] 1089-7690
  • [Journal-full-title] The Journal of chemical physics
  • [ISO-abbreviation] J Chem Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Baran R: The red nail--always benign? Actas Dermosifiliogr; 2009 Nov;100 Suppl 1:106-13
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  • [Title] The red nail--always benign?
  • Red nail is a common disorder.
  • Only the former type can show histologically Bowen's disease or an amelanotic melanoma.
  • Among the polydactylous type, the nosologic position of the acantholytic and dyskeratotic naevus versus Darier's disease is still controversial.
  • Subungual warty dyskeratoma is rare, but other dermatoses such as lichen planus, psoriasis, mail melanoma and various tumours have to be ruled out.

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  • (PMID = 20096204.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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95. Orienti I, Zuccari G, Carosio R, Montaldo PG: Improvement of aqueous solubility of fenretinide and other hydrophobic anti-tumor drugs by complexation with amphiphilic dextrins. Drug Deliv; 2009 Oct;16(7):389-98
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  • The amphiphilic dextrins were obtained by conjugation of low molecular weight dextrin (average molecular weight 1670, average polymerization degree 9.33 glucose monomer) with hydrocarbon chains at substitution degree of about 0.1 mole hydrocarbon chain per mole of glucose monomer, as confirmed by 1H-NMR spectra.

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  • (PMID = 19624248.001).
  • [ISSN] 1521-0464
  • [Journal-full-title] Drug delivery
  • [ISO-abbreviation] Drug Deliv
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Dextrins; 0 / Drug Carriers; 0 / Surface-Active Agents; 187EJ7QEXL / Fenretinide
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96. Zurita F, Carmona FD, Lupiáñez DG, Barrionuevo FJ, Guioli S, Burgos M, Jiménez R: Meiosis onset is postponed to postnatal stages during ovotestis development in female moles. Sex Dev; 2007;1(1):66-76
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  • [Title] Meiosis onset is postponed to postnatal stages during ovotestis development in female moles.
  • The gonads of female moles (genus Talpa) develop according to a testis-like pattern which results in the formation of ovotestes.
  • In this paper, we studied the expression pattern of several pre-meiotic and meiotic germ cell markers, in order to establish the precise time of meiosis onset in the mole species T. occidentalis, and to investigate the location and possible role of germ cells in ovotestis organogenesis.
  • (1) the asymmetrical distribution of primordial germ cells, which concentrate in the cortex of the XX gonad, is brought about by germ cell depletion from the medulla between the s5a and s5b stages, (2) XX germ cells enter meiosis postnatally, which is quite exceptional among eutherian mammals, and (3) XX but not XY germ cells of moles express DMRT1 during premeiotic stages of development, an expression pattern not described previously in vertebrates.
  • [MeSH-major] Gonads / cytology. Gonads / embryology. Meiosis. Moles / embryology

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  • [Copyright] (c) 2007 S. Karger AG, Basel
  • (PMID = 18391517.001).
  • [ISSN] 1661-5433
  • [Journal-full-title] Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation
  • [ISO-abbreviation] Sex Dev
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / MC/ U117562207
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / DMRT1 protein; 0 / Transcription Factors
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97. Lewis ER, Narins PM, Jarvis JU, Bronner G, Mason MJ: Preliminary evidence for the use of microseismic cues for navigation by the Namib golden mole. J Acoust Soc Am; 2006 Feb;119(2):1260-8
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  • [Title] Preliminary evidence for the use of microseismic cues for navigation by the Namib golden mole.
  • Insect prey of the Namib golden mole congregate beneath clumps of grass scattered among the sand dunes of the Namib Desert.
  • While foraging in the sand-swimming mode (a few centimeters below the surface of the sand), some moles apparently were attracted toward manmade sources emitting vibrations matching those recorded from the grass clumps.
  • [MeSH-major] Environment. Feeding Behavior. Locomotion / physiology. Moles / physiology. Vibration

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  • (PMID = 16521787.001).
  • [ISSN] 0001-4966
  • [Journal-full-title] The Journal of the Acoustical Society of America
  • [ISO-abbreviation] J. Acoust. Soc. Am.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / DC00222
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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98. Barros Jde N, Lowen MS, Mascaro VL, Andrade TP, Martins MC: Impression cytology features of conjunctival nevi reported as more noticeable. Arq Bras Oftalmol; 2009 Mar-Apr;72(2):205-10
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  • [Title] Impression cytology features of conjunctival nevi reported as more noticeable.
  • PURPOSE: To report the impression cytology features of conjunctival nevi reported as more noticeable.
  • On slit-lamp examination, a clinical diagnosis of nevus was made and lesions underwent impression cytology using acetate cellulose strips and a combined staining with PAS, H&E and Papanicolaou.
  • RESULTS: Impression cytology examination revealed nests or cluster of nevus cells within the epithelium layer containing or not mucous-secreting goblet cells in 32 cases (91.4%).
  • Ten patients (28.5%) had the tumor removed and histopathological diagnosis was compound nevus in 8 eyes (1 from caruncle, 1 from plica semilunaris and 6 from bulbar conjunctiva) and subepithelial nevus from bulbar conjunctiva (2 eyes).
  • CONCLUSION: Optical microscopy analysis of the impression cytology specimens confirmed the clinical diagnosis by demonstrating typical histopathological features of the superficial layers from conjunctival nevi in 91.4% of the cases.
  • For amelanotic nevi IC can also allow a differential diagnosis from other nonpigmented lesions.
  • The technique does not replace histopathological examination, but additionally, may assist in evaluating nevus cells in children and adults.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Nevus / pathology

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  • (PMID = 19466330.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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99. Brockmann K, Happle R, Oeffner F, König A: Monozygotic twins discordant for Proteus syndrome. Am J Med Genet A; 2008 Aug 15;146A(16):2122-5
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  • Proteus syndrome is a rare, complex disorder predominantly characterized by asymmetric overgrowth of body parts, connective tissue and epidermal nevi, and vascular malformations.
  • The affected 9-year-old boy showed progressive postnatal overgrowth of his right leg and foot and asymmetric progressive overgrowth of single toes with a small cerebriform connective tissue nevus on his right fourth toe.

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  • [Copyright] Copyright 2008 Wiley-Liss, Inc.
  • (PMID = 18627057.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Twin Study
  • [Publication-country] United States
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100. Yamashita T, Uno T, Ishikawa Y: Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms. Bioorg Med Chem; 2005 Apr 1;13(7):2423-30
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  • One mole equivalent of the isomers was sufficient to stabilize the quadruplex.

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  • (PMID = 15755644.001).
  • [ISSN] 0968-0896
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cations; 0 / Porphyrins; 5Z93L87A1R / Guanine; 9007-49-2 / DNA
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