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1. Correia FM, Seabra B, Rego A, Duarte R, Miranda J: Cystic lymphangioma of the mediastinum. J Bras Pneumol; 2008 Nov;34(11):982-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic lymphangioma of the mediastinum.
  • Cystic lymphangioma is a rare congenital benign tumor.
  • Only 1% are located in the mediastinum.
  • Here, we present the case of a 50-year-old male with cystic lymphangioma of the mediastinum, detected on a routine chest X-ray.
  • [MeSH-major] Lymphangioma, Cystic / radiography. Mediastinal Neoplasms / radiography
  • [MeSH-minor] Diagnosis, Differential. Humans. Incidental Findings. Male. Middle Aged

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  • (PMID = 19099107.001).
  • [ISSN] 1806-3756
  • [Journal-full-title] Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • [ISO-abbreviation] J Bras Pneumol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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2. Ulku R, Yilmaz F, Eren S, Onat S: Lymphoepithelial cyst of the mediastinum. Tex Heart Inst J; 2005;32(3):440-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoepithelial cyst of the mediastinum.
  • We report a rare case of lymphoepithelial cyst of the mediastinum.
  • A 38-year-old woman was found to have a right paratracheal mediastinal mass on chest radiograph.
  • The encapsulated mass was situated in the upper mediastinum and was adherent to the trachea.
  • These findings were consistent with a diagnosis of multicystic lymphoepithelial cyst.

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  • [Cites] Am J Clin Pathol. 1989 Dec;92(6):808-13 [2556020.001]
  • [Cites] Respiration. 1995;62(2):110-3 [7784708.001]
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  • [Cites] Chest. 1997 Nov 5;112(5):1344-57 [9367479.001]
  • (PMID = 16392239.001).
  • [ISSN] 0730-2347
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1336730
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3. Andreu C, Yat-Wah P, Fraga J, Olivera MJ, Caballero P: [Necrotic lipoma of the posterior mediastinum]. Arch Bronconeumol; 2008 Nov;44(11):641-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Necrotic lipoma of the posterior mediastinum].
  • [Transliterated title] Lipoma infartado del mediastino posterior.
  • Intrathoracic lipomas are rare, but found most commonly in the pleura or anterior mediastinum.
  • Computed tomography shows fatty, homogenous content of the mass and will establish the diagnosis.
  • We describe a case of lipoma in the posterior mediastinum that contained solid areas on computed tomography.
  • [MeSH-major] Fat Necrosis / etiology. Infarction / complications. Lipoma / blood supply. Mediastinal Neoplasms / blood supply

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  • (PMID = 19007571.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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4. Ernst S, Sanchez-Quintana D, Ho SY: Anatomy of the Pericardial Space and Mediastinum: Relevance to Epicardial Mapping and Ablation. Card Electrophysiol Clin; 2010 Mar;2(1):1-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anatomy of the Pericardial Space and Mediastinum: Relevance to Epicardial Mapping and Ablation.

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  • [Copyright] Copyright © 2010. Published by Elsevier Inc.
  • (PMID = 28770727.001).
  • [ISSN] 1877-9190
  • [Journal-full-title] Cardiac electrophysiology clinics
  • [ISO-abbreviation] Card Electrophysiol Clin
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Weinrich M, Seidel R, Graeter TP, Schäfers HJ, Lausberg HF: [Cystic lesion of the dorsal mediastinum]. Chirurg; 2005 Sep;76(9):894-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cystic lesion of the dorsal mediastinum].
  • [Transliterated title] Zystische Raumforderung im hinteren Mediastinum.
  • We present the case of a 52-year-old male who underwent thoracotomy for resection of a suspected bronchogenic cyst in the right posterior mediastinum.
  • The size of the tumor had increased over years, according to repeated X-rays, and the cyst became symptomatic with obstruction of the right subclavian and jugular veins.
  • [MeSH-major] Echinococcosis / diagnosis. Mediastinal Cyst / etiology. Mediastinal Diseases / diagnosis
  • [MeSH-minor] Bronchogenic Cyst / diagnosis. Bronchogenic Cyst / pathology. Bronchogenic Cyst / surgery. Diagnosis, Differential. Humans. Image Enhancement. Magnetic Resonance Imaging. Male. Middle Aged. Thoracotomy

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  • [Cites] Chest. 1997 Nov 5;112(5):1344-57 [9367479.001]
  • [Cites] Chest. 1997 Aug;112(2):511-22 [9266892.001]
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  • [Cites] Eur J Radiol. 1991 Mar-Apr;12 (2):150-9 [2037004.001]
  • [Cites] J Radiol. 1993 Nov;74(11):541-8 [8283408.001]
  • (PMID = 15864485.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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6. Delso G, Martinez-Möller A, Bundschuh RA, Nekolla SG, Ziegler SI: The effect of limited MR field of view in MR/PET attenuation correction. Med Phys; 2010 Jun;37(6Part1):2804-2812

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A set of spherical lesions was simulated in the lungs and mediastinum of a patient.

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  • [Copyright] © 2010 American Association of Physicists in Medicine.
  • (PMID = 28512938.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Computed tomography / Image reconstruction / Image scanners / Lungs / MR / MR/PET / Magnetic resonance / Magnetic resonance imaging / Medical image reconstruction / Medical imaging / Medical magnetic resonance imaging / PET / Positron emission tomography / Positron emission tomography (PET) / Reconstruction / Segmentation / Tissues / attenuation / biomedical MRI / computerised tomography / field of view / image reconstruction / image segmentation / lung / medical image processing / positron emission tomography
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7. Hirai K, Takeuchi S, Bessho R, Ohaki Y, Koizumi K, Shimizu K: Venous hemangioma of the anterior mediastinum. J Nippon Med Sch; 2010 Apr;77(2):115-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Venous hemangioma of the anterior mediastinum.
  • We report a rare case of venous hemangioma (VH) of the anterior mediastinum in a 56-year-old man admitted to our hospital because of hematemesis.
  • Both CT and magnetic resonance imaging (MRI) suggested a solid tumor such as a thymoma or neurogenic tumor rather than a vascular neoplasm.
  • [MeSH-major] Hemangioma / diagnosis. Mediastinal Neoplasms / diagnosis. Thymus Neoplasms / diagnosis. Veins / pathology

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  • (PMID = 20453425.001).
  • [ISSN] 1345-4676
  • [Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
  • [ISO-abbreviation] J Nippon Med Sch
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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8. Angulo Hervías E, Lample Lacasa C, Crespo Rodríguez AM, Yagüe Romeo D: [Primary mesenchymal chondrosarcoma of the mediastinum]. Radiologia; 2007 Sep-Oct;49(5):358-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary mesenchymal chondrosarcoma of the mediastinum].
  • [Transliterated title] Condrosarcoma mesenquimal primario en el mediastino.
  • Cartilaginous lesions of the mediastinum are quite rare and primary cartilage forming tumors arising within the mediastinum are even more exceptional.
  • However, certain characteristics can orient the diagnosis.
  • They are presented one mediastinal chondrosarcoma case in adult patient of patho-anatomical diagnosis.
  • [MeSH-major] Chondrosarcoma, Mesenchymal / diagnosis. Mediastinal Neoplasms / diagnosis

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  • (PMID = 17910876.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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9. Braun B, Blank W: [Sonography of the neck and superior mediastinum]. Internist (Berl); 2005 Oct;46(10):1133-45; quiz 1146
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sonography of the neck and superior mediastinum].
  • [Transliterated title] Sonographie von Hals und oberem Mediastinum.
  • Sonography of the neck and superior mediastinum is a very instructive method of investigation.
  • The pharyngeal and retropharyngeal space, the base of the brain and the posterior mediastinum are difficult to access by sonography.
  • The investigator must therefore arrange for supplementary imaging procedures such as CT, MRI or thyroid scintigraphy in unclear cases, e.g. in diagnosis and staging of tumors.
  • Mediastinal space occupations are most frequent in the anterior upper mediastinum.
  • [MeSH-major] Head and Neck Neoplasms / diagnostic imaging. Image Enhancement / methods. Mediastinum / diagnostic imaging. Neck / diagnostic imaging. Thoracic Diseases / diagnostic imaging. Ultrasonography / methods

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  • [Cites] Vasa. 1992;21(1):57-62 [1580092.001]
  • (PMID = 16075213.001).
  • [ISSN] 0020-9554
  • [Journal-full-title] Der Internist
  • [ISO-abbreviation] Internist (Berl)
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 6
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10. Kujath P, Scheele J, Esnaashari H, Shekarriz H, Bouchard R: [Fungi in the mediastinum: rare, but relevant]. Mycoses; 2005;48 Suppl 1:18-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Fungi in the mediastinum: rare, but relevant].
  • [Transliterated title] Pilze im Mediastinum: Selten aber relevant.
  • Fungal infections of the mediastinum are rare.
  • There are five forms to be differentiated: (i) hematogenous fungal infection of the mediastinum after fungemia;.
  • (iv) infection of the mediastinum per continuitatem;.
  • (v) fungal infection of the posterior mediastinum after esophageal perforation.
  • The section results of one other patient with pulmonary aspergillosis showed a complete invasion of the mediastinum by Aspergillus fumigatus.
  • [MeSH-major] Fungi / pathogenicity. Mediastinitis / microbiology. Mediastinum / microbiology. Mycoses / microbiology

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  • (PMID = 15826282.001).
  • [ISSN] 0933-7407
  • [Journal-full-title] Mycoses
  • [ISO-abbreviation] Mycoses
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 10
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11. Günter E: [Transesophageal ultrasonography for mediastinum diagnostics]. Chirurg; 2008 Jan;79(1):56-60
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transesophageal ultrasonography for mediastinum diagnostics].
  • [Transliterated title] Transösophagealer Ultraschall zur Diagnostik im Mediastinum.
  • It is especially well suited to assessing mediastinal structures due to its transoesophageal approach and its high local definition.
  • The mediastinum can be viewed all the way from the tracheal bifurcation to the diaphragm.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnostic imaging. Endosonography. Lung Neoplasms / diagnostic imaging. Lymph Nodes / diagnostic imaging. Mediastinum / diagnostic imaging
  • [MeSH-minor] Biopsy, Fine-Needle. Bronchogenic Cyst / diagnostic imaging. Humans. Lung / pathology. Neoplasm Staging / methods

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  • (PMID = 18209979.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 37
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12. Eberhardt R, Becker HD, Herth FJ: [Endobronchial ultrasound for diagnosis of the mediastinum]. Chirurg; 2008 Jan;79(1):50-5
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endobronchial ultrasound for diagnosis of the mediastinum].
  • [Transliterated title] Endobronchialer Ultraschall zur Diagnostik im Mediastinum.
  • Two different techniques are available which improve sonographic diagnostics of the mediastinum and staging in patients with lung and non-lung cancer.
  • Especially the method combining EBUS and TBNA may replace more invasive methods such as mediastinoscopy for evaluating patients with unknown mediastinal lesions or for staging patients with lung cancer.
  • [MeSH-major] Bronchoscopes. Carcinoma, Non-Small-Cell Lung / diagnostic imaging. Endosonography. Lung Neoplasms / diagnostic imaging. Lymph Nodes / diagnostic imaging. Mediastinum / diagnostic imaging
  • [MeSH-minor] Biopsy, Needle / methods. Humans. Lung / pathology. Neoplasm Staging / methods. Ultrasonography, Interventional

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  • (PMID = 18064427.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 36
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13. Jurecka T, Skorkovská S, Coupková H, Postránecká V: [Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum]. Klin Onkol; 2009;22(4):179-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum].
  • [Transliterated title] Duhovková metastáza jako iniciální manifestace bronchogenního malobunecného karcinomu diseminovaného do mediastina.
  • Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma.
  • [MeSH-major] Iris Neoplasms / secondary. Lung Neoplasms / pathology. Mediastinal Neoplasms / secondary. Small Cell Lung Carcinoma / secondary

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  • (PMID = 19731881.001).
  • [ISSN] 0862-495X
  • [Journal-full-title] Klinická onkologie : casopis Ceské a Slovenské onkologické spolecnosti
  • [ISO-abbreviation] Klin Onkol
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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14. Duwe BV, Sterman DH, Musani AI: Tumors of the mediastinum. Chest; 2005 Oct;128(4):2893-909
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumors of the mediastinum.
  • Tumors of the mediastinum represent a wide diversity of disease states.
  • The location and composition of a mass is critical to narrowing the differential diagnosis.
  • The most common causes of an anterior mediastinal mass include the following: thymoma; teratoma; thyroid disease; and lymphoma.
  • Masses of the middle mediastinum are typically congenital cysts, including foregut and pericardial cysts, while those that arise in the posterior mediastinum are often neurogenic tumors.
  • The clinical sequelae of mediastinal masses can range from being asymptomatic to producing symptoms of cough, chest pain, and dyspnea.
  • This article will review the anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features, and therapeutic options of the most commonly encountered masses.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Lymphoma / diagnosis. Neoplasm Staging. Teratoma / diagnosis. Thymoma / diagnosis. Thymus Neoplasms / diagnosis. Thyroid Neoplasms / diagnosis

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  • (PMID = 16236967.001).
  • [ISSN] 0012-3692
  • [Journal-full-title] Chest
  • [ISO-abbreviation] Chest
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 154
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15. Feldman DR, Sheinfeld J, Bajorin DF, Fischer P, Turkula S, Ishill N, Patil S, Bains M, Bosl GJ, Motzer RJ: Paclitaxel (T) plus ifosfamide (I) followed by high-dose carboplatin (C) and etoposide (E) with autologous stem cell support for patients (pts) with previously treated germ cell tumors (GCT): TI-CE results and prognostic factor analysis in 107 pts. J Clin Oncol; 2009 May 20;27(15_suppl):5027

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 5027 Background: Pts with incomplete response (IR) to first-line chemotherapy or relapsed primary mediastinal non-seminomatous GCT (NSGCT) have <10% 3-year (yr) survival with conventional-dose salvage regimens (Cancer. 67:1305).
  • RESULTS: Of 107 pts, primary site was testis in 72, mediastinum (all NSGCT) in 21, and other in 14.
  • 5/21 (24%) primary mediastinal NSGCT and 2/7 late relapses are continuously disease-free.
  • On multivariate analysis, primary mediastinal site (p = 0.0002), ≥2 lines of prior therapy (p = 0.0005), baseline HCG >1000 (p = 0.01), and lung metastases (p = 0.02) significantly predicted adverse DFS.
  • Mediastinal primary site and ≥2 lines of prior therapy were most predictive of adverse DFS.

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  • (PMID = 27962915.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Gandola L, Nantron M, Marchianò A, Pession A, Indolfi P, Di Cataldo A, Collini P, Arcamone G, Fossati Bellani F, Spreafico F: Outcome in stage IV Wilms tumor treated according to the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) trials. J Clin Oncol; 2009 May 20;27(15_suppl):10031

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcome in stage IV Wilms tumor treated according to the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) trials.
  • : 10031 Background: Children with metastases at diagnosis for Wilms tumor (WT) still display a worse prognosis compared to localized disease.
  • Adjuvant therapy included 8-month 3-drug chemotherapy for non anaplastic "local" tumor stage I to III (flank RT for stage III), or an intensified regimen for anaplastic histology, adding etoposide, carboplatinum and ifosfamide (6 patients).
  • Overall 19 tumor failure occurred (3 in anaplastic tumors): metastases progression 9, abdominal relapse 5 (combined to liver and mediastinum in 1 case each), lung 4, liver 1.
  • The impact of metastatic tumor burden deserves further analysis.

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  • (PMID = 27962576.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Gerrard M, Waxman I, Sposto R, Auperin A, Harrison L, Pinkerton R, Perkins SL, McCarthy K, Raphael M, Patte C, Cairo MS, FAB/LMB 96 Trial: Association of primary mediastinal B-cell lymphoma (PMBL) in children (C) and adolescents (A) with a significantly inferior prognosis: Final results of the FAB/LMB 96 trial. J Clin Oncol; 2009 May 20;27(15_suppl):10001

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of primary mediastinal B-cell lymphoma (PMBL) in children (C) and adolescents (A) with a significantly inferior prognosis: Final results of the FAB/LMB 96 trial.
  • : 10001 Background: Single pediatric cooperative group studies have demonstrated an EFS ranging from 65 - 75% in C & A with large cell lymphomas arising in the mediastinum (Lones/Cairo et al, J Clin Oncol, 2000; Burkhardt/Reiter et al, Br J Haematol, 2005; Seidman/Reiter et al, J Clin Oncol, 2003).

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  • (PMID = 27962546.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Medford-Davis LN, Varlotto J, Recht A, Flickinger JC, DeCamp MM: Varying recurrence rates and risk factors associated with different definitions of local recurrence in patients with surgically resected stage I non-small cell lung cancer. J Clin Oncol; 2009 May 20;27(15_suppl):7583

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Local recurrence was defined as either: "radiation" (i.e., recurrences confined to the post-operative radiotherapy fields used in the Phase III trial of adjuvant radiotherapy by Trodella et al) (LRR), including the bronchial stump, staple line, the ipsilateral hilum, and ipsilateral mediastinum; or "comprehensive" (LRC), including these sites plus the ipsilateral lung and contralateral mediastinal and hilar nodes.
  • Significant risk factors for LRC on multivariable analysis were diabetes, lymphatic vascular invasion and tumor size; significant factors for LRR were resection of less than a lobe and lymphatic vascular invasion.
  • Significant risk factors for distant failure were histology when using the LRC definitions and tumor size using the LRR definition.

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  • (PMID = 27963380.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Darling G, Maziak D, Inculet R, Gulenchyn K, Driedger A, Ung Y, Miller J, Gu C, Evans W, Levine M: PET-CT compared to invasive mediastinal staging in non-small cell lung cancer (NSCLC). J Clin Oncol; 2009 May 20;27(15_suppl):7575

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PET-CT compared to invasive mediastinal staging in non-small cell lung cancer (NSCLC).
  • <sup>18</sup>FDG PET-CT is useful in identifying patients with mediastinal disease not evident by CT.
  • METHODS: In this analysis, we determined the accuracy of PET-CT in mediastinal staging compared to invasive surgical staging either by M alone or by M and T.
  • Patients in the PET-CT arm had invasive mediastinal staging either by M or mediastinal nodal sampling at T.
  • RESULTS: M was performed in 81 of 143 patients in the PET-CT arm; the remainder had mediastinal nodal staging at T.
  • Of 21 patients with a positive PET-CT, 7 did not have tumor.
  • Based on PET-CT alone, 7 patients would have been denied T if PET-CT abnormalities had not been evaluated with invasive mediastinal staging.
  • CONCLUSIONS: Mediastinal abnormalities on PET-CT should be confirmed by invasive mediastinal staging because of the risk of a false positive test.
  • If PET-CT is negative in the mediastinum, the likelihood of occult metastatic disease in the mediastinum is very low and invasive staging may not be required depending on the clinical context.

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  • (PMID = 27963383.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Indelicato DJ, Keole SR, Shahlaee AH, Morris CG, Gibbs CP, Scarborough MT, Islam S, Marcus RB: Ewing tumors of the chest wall: Local control and long-term outcomes. J Clin Oncol; 2009 May 20;27(15_suppl):e21501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e21501 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 4 pts had a previous history of mediastinal radiation for Hodgkin's and non-Hodgkin's linfomas.
  • 5 mediastinal tumours were located as follows: 2 in anterior part, 1 in posterior and 2 in the middle (sarcomas of the heart).
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • CONCLUSIONS: Primary sarcomas of the lungs and mediastinum have a very severe prognosis.

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  • (PMID = 27963390.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Weyl Ben Arush M Sr, Hersalis Eldar A, Abrahami G, Attias D, Ben Barak A, Dvir R, Gabriel H, Kapelushnik J, Kaplinsky H, Vilk-Revel S: Burkitt lymphoma in children: The Israel Society of Pediatric Hematology Oncology retrospective study. J Clin Oncol; 2009 May 20;27(15_suppl):10051

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Initial disease sites included the abdomen in 43%, head and neck in 45%, mediastinum in 7%.
  • In group A: there were neither events nor deaths in this group, 6 patients relapsed in group B, among them 4 patients had died, tumor lysis syndrome in 3 patients, death of toxicity in 1 patient.
  • OS according to primary site: bone and ovary (100%), head and neck (95%), abdomen (92%) and mediastinum (50%) (p = 0.003).
  • All of the mediastinal tumors were of DLBC origin, but when comparing the DLBC to other histologies, no significant difference in outcome were found.(DLBC: 81.8%, other B line: 90.9%).
  • Patients with primary DLBC mediastinal mass had a significantly reduced overall survival, indicating the need for a different therapeutic approach.

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  • (PMID = 27962447.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Comandone A, Boglione A, Pochettino P, Berno E, Inguì M, Papotti M, Borasio P, Maggi G, Brach Del Prever E, Gino G: Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):e21509

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas.
  • : e21509 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 4 pts had a previous history of mediastinal radiation for Hodgkin's and non-Hodgkin's linfomas.
  • 5 mediastinal tumours were located as follows: 2 in anterior part, 1 in posterior and 2 in the middle (sarcomas of the heart).
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • CONCLUSIONS: Primary sarcomas of the lungs and mediastinum have a very severe prognosis.

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  • (PMID = 27963441.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Haveman JW, Jörning PJ: [A man with a widened mediastinum after trauma]. Ned Tijdschr Geneeskd; 2009;153:B472

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A man with a widened mediastinum after trauma].
  • [Transliterated title] Een man met een verbreed mediastinum na trauma.
  • A 36-year-old male patient with a high energy trauma had a widened mediastinum caused by a traumatic transsection of the aorta.
  • [MeSH-major] Aortic Rupture / diagnosis. Aortic Rupture / surgery. Mediastinum / pathology. Suicide, Attempted

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  • (PMID = 19857295.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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24. Siemsen M, Steffensen IE, Iversen M, Andersen C: [Endobronchial mediastinal ultrasound with biopsy]. Ugeskr Laeger; 2010 Apr 26;172(17):1285-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endobronchial mediastinal ultrasound with biopsy].
  • [Transliterated title] Endobronkial ultralydsskanning af mediastinum med biopsi.
  • EBUS is mostly used for staging of lung cancer patients, but EBUS is now used worldwide as a diagnostic tool in patients with mediastinal tumours or adenopathy.
  • MATERIAL AND METHODS: In this paper, we report of the result of the first 100 EBUS patients referred for further investigation of mediastinal adenopathy or tumour found via CT.
  • RESULTS: A total of 46 patients were known to have or have had cancer; in 20 of these patients we found cancer in the mediastinum by EBUS-TBNA, 24 patients had lymph node aspirates without cancer and in two patients the aspirate was inconclusive.
  • The remaining 49 patients all had a record of non-malignant medical disease; 22 of these patients were found to have cancer in the mediastinum, one patient had cancer-suspect EBUS-TBNA, 24 had lymph node aspirates without malignancy and in two patients the aspirate was inconclusive.
  • CONCLUSION: We conclude that EBUS-TBNA is a safe and accurate diagnostic tool in the evaluation of mediastinum in patients with cancer as well as in patients with non-malignant disease.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Mediastinal Neoplasms / pathology. Mediastinum / pathology. Ultrasonography, Interventional / methods
  • [MeSH-minor] Endosonography / methods. Humans. Lymphatic Metastasis / pathology. Lymphatic Metastasis / ultrasonography. Neoplasm Staging. Sensitivity and Specificity

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  • (PMID = 20444395.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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25. Abakumov MM, Shamba KhL, Danielian ShN: [Spontaneous emphysema of the mediastinum]. Khirurgiia (Mosk); 2010;(10):17-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Spontaneous emphysema of the mediastinum].
  • Cases of 104 patients with the spontaneous emphysema of the mediastinum were thoroughly analyzed.
  • Surgical treatment is indicated to less then 4% of patients with spontaneous mediastinal emphysema.
  • [MeSH-major] Mediastinal Emphysema / radiography. Mediastinal Emphysema / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Sex Factors. Young Adult

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  • (PMID = 21169925.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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26. Wick MR: Cystic lesions of the mediastinum. Semin Diagn Pathol; 2005 Aug;22(3):241-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic lesions of the mediastinum.
  • Cysts of the mediastinum comprise a relatively diverse group of lesions that include neoplastic and nonneoplastic constituents, the latter of which are largely congenital in nature.
  • [MeSH-major] Mediastinal Cyst / pathology. Mediastinal Neoplasms / pathology
  • [MeSH-minor] Humans. Mediastinum / embryology. Mediastinum / growth & development

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  • (PMID = 16711405.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 108
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27. Athanassiadi KA: Infections of the mediastinum. Thorac Surg Clin; 2009 Feb;19(1):37-45, vi

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infections of the mediastinum.
  • Infections of the mediastinum (ie, mediastinitis) are serious, are associated with high morbidity and mortality, and may result from adjacent disease with direct extension, hematogenous spread, or direct introduction into the mediastinal space.
  • Today, the most common cause of mediastinitis is direct invasion of the mediastinum after surgical intervention.
  • [MeSH-major] Mediastinitis / diagnosis. Mediastinitis / therapy
  • [MeSH-minor] Acute Disease. Anti-Bacterial Agents / therapeutic use. Chronic Disease. Drainage. Humans. Mediastinum / radiography. Postoperative Complications / therapy. Sternum / surgery

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  • (PMID = 19288819.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
  • [Number-of-references] 69
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28. Palimento D, Picchio M: Meningioma of the mediastinum causing spontaneous hemothorax. Ann Thorac Surg; 2006 May;81(5):1903-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meningioma of the mediastinum causing spontaneous hemothorax.
  • Mediastinal tumors may rarely cause spontaneous hemothorax.
  • We report a case of angioblastic meningioma of the posterior mediastinum causing spontaneous hemothorax.
  • [MeSH-major] Hemothorax / etiology. Mediastinum. Meningioma / complications. Thoracic Neoplasms / complications

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  • (PMID = 16631706.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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29. Trainer S, Bergmann T, Bölükbas S, Weissbach L, Figge M, Schirren J: [The approach to tumors of the retrocrural mediastinum]. Chirurg; 2008 Jan;79(1):26-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The approach to tumors of the retrocrural mediastinum].
  • [Transliterated title] Zugang zu retrokruralen Tumoren des Mediastinums.
  • Retrocrural tumors of the lower posterior mediastinum are rare.
  • [MeSH-major] Diaphragm / surgery. Mediastinal Neoplasms / surgery. Neoplasm, Residual / surgery. Neoplasms, Germ Cell and Embryonal / surgery
  • [MeSH-minor] Disease-Free Survival. Humans. Lymph Node Excision. Lymphatic Metastasis. Magnetic Resonance Imaging. Prognosis. Ribs / surgery. Teratoma / diagnosis. Teratoma / diagnostic imaging. Teratoma / secondary. Teratoma / surgery. Thoracotomy. Tomography, X-Ray Computed. Treatment Outcome

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  • [Cites] Semin Thorac Cardiovasc Surg. 1992 Oct;4(4):314-9 [1457572.001]
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  • (PMID = 18209978.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 8
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30. Zidane A, Atoini F, Arsalane A, Traibi A, Redouane B, Jidal M, El Bouzidi A, Kabiri EH: [Primary leiomyosarcoma of visceral mediastinum]. Rev Pneumol Clin; 2009 Apr;65(2):93-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary leiomyosarcoma of visceral mediastinum].
  • [Transliterated title] Léiomyosarcome primitif du médiastin viscéral.
  • Primary leiomyosarcoma of the thorax is a rare malignant mesenchymatous tumour.
  • Most of those tumours occurring in the mediastinum arise from the oesophagus and great vessels, whereas an appearance in the soft tissue of the mediastinum is extremely rare.
  • The rare incidence of this tumour and its slow growth reflect the difficulties in differential diagnosis according to their histopathology and location.
  • The authors describe a case of a leiomyosarcoma arising from soft tissue of the mediastinum and present a review of the literature.
  • [MeSH-major] Leiomyosarcoma / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 19375048.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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31. Tennyson C, Routledge T, Chambers A, Scarci M: Arteriovenous malformation in the anterior mediastinum. Ann Thorac Surg; 2010 Jul;90(1):e9-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Arteriovenous malformation in the anterior mediastinum.
  • Arteriovenous malformations of the mediastinum are exceedingly rare.
  • A literature search found fewer than 10 reported cases of congenital, posterior mediastinal arteriovenous malformations in adults.
  • We describe a giant anterior mediastinal arteriovenous malformation in a 29-year-old man.
  • [MeSH-major] Arteriovenous Malformations / diagnosis
  • [MeSH-minor] Adult. Humans. Male. Mediastinum

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20609737.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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32. Boateng P, Anjum W, Wechsler AS: Vascular lesions of the mediastinum. Thorac Surg Clin; 2009 Feb;19(1):91-105
MedlinePlus Health Information. consumer health - Vascular Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular lesions of the mediastinum.
  • Most mediastinal masses seen on thoracic imaging are of solid tumor origin.
  • As such, vascular lesions of the mediastinum can be mistaken for, or misinterpreted as, one of these more common mediastinal masses.
  • This article stresses the importance of considering vascular entities in the differential diagnosis of mediastinal masses.
  • [MeSH-major] Mediastinal Diseases / diagnosis. Mediastinum / blood supply. Vascular Diseases / diagnosis
  • [MeSH-minor] Aorta, Thoracic / abnormalities. Humans. Lymphangioma / diagnosis. Pulmonary Artery / abnormalities. Pulmonary Veins / abnormalities

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  • (PMID = 19288824.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 86
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33. Huang TW, Yang MH, Cheng YL, Tsai WC, Lee SC: Vagus nerve schwannoma in the middle mediastinum. Thorac Cardiovasc Surg; 2010 Aug;58(5):312-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vagus nerve schwannoma in the middle mediastinum.
  • Intrathoracic neurogenic tumors are generally located in the posterior mediastinum.
  • Tumors originating from the vagus nerve in the middle mediastinum are extremely rare.
  • This report describes a patient with a huge intrathoracic schwannoma of the vagus nerve in the middle mediastinum and reviews the literature.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Neurilemmoma / diagnosis. Vagus Nerve / pathology. Vagus Nerve Diseases / diagnosis

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  • [Copyright] Copyright (c) Georg Thieme Verlag KG Stuttgart-New York.
  • [CommentIn] Thorac Cardiovasc Surg. 2011 Feb;59(1):63-4 [21243580.001]
  • (PMID = 20680914.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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34. Saint-Blancard P, Harket A, Bonnichon A, Jancovici R: [Neurogenic spindle-cell tumors of the mediastinum: two cases]. Presse Med; 2008 Feb;37(2 Pt 1):229-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neurogenic spindle-cell tumors of the mediastinum: two cases].
  • [Transliterated title] Tumeurs nerveuses à cellules fusiformes du médiastin: deux observations.
  • They are commonly found, however, in the mediastinum, most often in its posterior compartment.
  • Neurogenic tumors can be benign or malignant.
  • CASES: We report one case of a malignant peripheral nerve sheath tumor in the posterior mediastinum of a 29-year-old man and another of a schwannoma of the anterior mediastinum, in an 82-year-old woman.
  • DISCUSSION: Neurogenic tumors of spindle-shaped cells in the mediastinum are generally benign, but can be malignant.
  • Often asymptomatic, they are usually detected on standard pulmonary radiography, but computerized tomography is necessary, supplemented by magnetic resonance imaging, especially for posterior mediastinal tumors, to provide additional information and to assess its possible extension to adjacent structures.
  • Radiographic, clinical, and especially histopathological features are essential for diagnosis.
  • [MeSH-major] Carcinoma. Mediastinal Neoplasms

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  • (PMID = 17988829.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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35. Ortega PF, Sosa LA, Patel M, Zambrano E: Cystic paraganglioma of the anterior mediastinum. Ann Diagn Pathol; 2010 Oct;14(5):341-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic paraganglioma of the anterior mediastinum.
  • Paraganglioma of the mediastinum is an extremely uncommon neoplasm, and the concurrent finding of cystic changes has yet to be reported in the literature.
  • Imaging studies revealed a well-defined cystic lesion located in the anterior mediastinum, with the patient undergoing subsequent surgical resection of the mass.
  • Immunohistochemical stains showed strong positivity for chromogranin, synaptophysin, and CD56 in the epithelioid cells, with negative staining for cytokeratin AE1/AE3, confirming the diagnosis of paraganglioma.
  • S-100 was positive in the intervening sustentacular cells throughout the tumor.
  • Cystic paraganglioma of the anterior mediastinum is a rare neoplasm, which , to our knowledge, has not yet been reported in the English literature, and should be added to the differential diagnosis of cystic lesions of the mediastinum.
  • [MeSH-major] Cysts / pathology. Mediastinal Neoplasms / pathology. Paraganglioma / pathology
  • [MeSH-minor] Adult. Antigens, CD56 / metabolism. Biomarkers, Tumor / metabolism. Chromogranins / metabolism. Epithelioid Cells / chemistry. Humans. Immunohistochemistry. Male. Mediastinum / pathology. Mediastinum / surgery. S100 Proteins / metabolism. Synaptophysin / metabolism. Tomography, X-Ray Computed

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20850697.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Biomarkers, Tumor; 0 / Chromogranins; 0 / S100 Proteins; 0 / Synaptophysin
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36. Kadowaki T, Hamada H, Yokoyama A, Katayama H, Aramoto T, Ueda N, Tomioka H, Higaki J: Thymic carcinoma originating from the mid-posterior mediastinum. Respirology; 2005 Nov;10(5):689-91
MedlinePlus Health Information. consumer health - Lymphatic Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thymic carcinoma originating from the mid-posterior mediastinum.
  • Initial chest CT revealed a mass at the mid-posterior mediastinum.
  • Transbronchial fine needle biopsy of the mass failed to provide a definite diagnosis.
  • The mass was treated as a malignant mediastinal tumour, and chemoradiotherapy was performed as initial treatment.
  • This case is interesting in that the mid-posterior mediastinum is the site where thymic carcinoma is least likely to originate.
  • [MeSH-major] Choristoma / pathology. Lymphatic Diseases / pathology. Mediastinal Neoplasms / pathology. Thymoma / pathology. Thymus Gland

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  • (PMID = 16268928.001).
  • [ISSN] 1323-7799
  • [Journal-full-title] Respirology (Carlton, Vic.)
  • [ISO-abbreviation] Respirology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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37. Kim JY, Hofstetter WL: Tumors of the mediastinum and chest wall. Surg Clin North Am; 2010 Oct;90(5):1019-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumors of the mediastinum and chest wall.
  • Primary tumors of the mediastinum and chest wall comprise a diverse group of conditions with a wide range of presentations.
  • A thorough knowledge of thoracic anatomy is essential for appropriate diagnosis and treatment.
  • Although surgery is the mainstay of therapy for most mediastinal and chest wall tumors, a multidisciplinary approach is valuable in many cases.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis. Thoracic Neoplasms / diagnosis. Thoracic Wall. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans

  • MedlinePlus Health Information. consumer health - Thymus Cancer.
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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20955881.001).
  • [ISSN] 1558-3171
  • [Journal-full-title] The Surgical clinics of North America
  • [ISO-abbreviation] Surg. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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38. Priola AM, Priola SM, Cardinale L, Cataldi A, Fava C: The anterior mediastinum: diseases. Radiol Med; 2006 Apr;111(3):312-42
MedlinePlus Health Information. consumer health - Diagnostic Imaging.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The anterior mediastinum: diseases.
  • Mediastinal tumours are frequently asymptomatic and first noted on routine chest radiograph.
  • Primary tumours in the anterior mediastinum account for half of all mediastinal masses.
  • They comprise various benign and malignant neoplasms, but a wide variety of nonneoplastic lesions (developmental, inflammatory) can present as a localised mass in this compartment.
  • The most common primary anterior mediastinal tumours are thymoma, teratoma and lymphoma; all other lesions are rare.
  • Understanding the pathology, clinical presentation, imaging and diagnosis of the major tumour types is instrumental in the safe and efficient work-up of a mediastinal mass.
  • Patients with primary mediastinal masses and cysts will usually undergo surgical resection; radiological and clinical features should prompt limited biopsy specimens followed by oncologic consultation, and chemotherapy or radiotherapy when appropriate.
  • The objective of this review was to examine the role of diagnostic imaging in the management of masses of the anterior mediastinum.
  • [MeSH-major] Diagnostic Imaging. Mediastinal Diseases / diagnosis. Mediastinal Neoplasms / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Humans. Lymphatic Diseases / diagnosis. Mediastinal Cyst / diagnosis. Mediastinitis / diagnosis. Neoplasms, Germ Cell and Embryonal / diagnosis. Thymus Gland / pathology. Tomography, Spiral Computed

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  • (PMID = 16683081.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 78
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39. Ayadi-Kaddour A, Chaabouni N, Smati B, Mehouachi R, Djilani H, El Mezni F: [Desmoid fibromatosis of the posterior mediastinum]. Rev Mal Respir; 2008 Jan;25(1):82-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoid fibromatosis of the posterior mediastinum].
  • [Transliterated title] Fibromatose de type desmoïde du médiastin postérieur.
  • Although they are considered histologically benign they behave aggressively locally and relapse repeatedly after surgical excision.
  • Mediastinal localisation is very rare.
  • We describe a case of de novo fibromatosis of the posterior mediastinum in a 61 year old man with no history of thoracotomy or trauma.
  • Although mediastinal fibromatosis is very uncommon physicians should be aware of this disease in order to ensure appropriate surgical treatment.
  • [MeSH-major] Fibromatosis, Aggressive / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 18288057.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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40. Bibas BJ, Terra RM, Fernandez A, Shiang C, Pêgo-Fernandes PM, Jatene FB: Leiomyomatous hamartoma of the posterior mediastinum. Ann Thorac Surg; 2010 Jan;89(1):304-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leiomyomatous hamartoma of the posterior mediastinum.
  • A posterior mediastinal mass was found in a 72-year-old man who complained of progressive shortness of breath.
  • The final diagnosis was a leiomyomatous hamartoma of the posterior mediastinum.
  • This is an unusual location for this type of tumor, and it has rarely been reported in the literature.
  • [MeSH-major] Hamartoma / diagnosis. Leiomyoma / diagnosis. Mediastinal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Radiography, Thoracic. Thoracotomy / methods. Tomography, X-Ray Computed

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20103268.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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41. Knight CS, Cerfolio RJ, Winokur TS: Angiomyolipoma of the anterior mediastinum. Ann Diagn Pathol; 2008 Aug;12(4):293-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyolipoma of the anterior mediastinum.
  • Angiomyolipoma is a benign tumor composed of varying proportions of smooth muscle cells, blood vessels, and adipose tissue that most commonly occurs in the kidney.
  • We present the case of an incidentally discovered angiomyolipoma in the anterior mediastinum.
  • [MeSH-major] Angiomyolipoma / pathology. Mediastinal Neoplasms / pathology
  • [MeSH-minor] Actins / metabolism. Antigens, Neoplasm / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Melanoma-Specific Antigens. Middle Aged. Muscle, Smooth / pathology. Neoplasm Proteins / metabolism. Thymoma / pathology. Thymus Neoplasms / pathology

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  • (PMID = 18620999.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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42. Biondi A, Rausei S, Cananzi FC, Zoccali M, D'Ugo S, Persiani R: [Surgical anatomy of the anterior mediastinum]. Ann Ital Chir; 2007 Sep-Oct;78(5):351-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical anatomy of the anterior mediastinum].
  • [Transliterated title] Anatomia chirurgica del mediastino anteriore.
  • The mediastinum is located from the thoracic inlet to the diaphragm between the left and right pleural cavities and contains vital structures of the circulatory, respiratory, digestive, and nervous system.
  • Over the years, since there are no fascial or anatomic planes, anatomists and radiologists have suggested various schemes for subdividing the mediastinum and several anatomical and radiological classifications of the mediastinum are reported in the literature.
  • The most popular of these scheme divides medistinum, for purposes of description, into two parts: an upper portion, above the upper level of the pericardium, which is named the superior mediastinum; and a lower portion, below the upper level of the pericardium.
  • For clinical purposes, the mediastinum may be subdivided into three major areas, i.e. anterior, middle, and posterior compartments.
  • The anterior mediastinum is defined as the region posterior to the sternum and anterior to the heart and brachiocephalic vessels.
  • This article will review surgical anatomy of the anterior mediastinum and will focus on the surgical approch to anterior mediastinum and thymic diseases.
  • [MeSH-major] Mediastinum / anatomy & histology. Mediastinum / surgery

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  • (PMID = 18338536.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 14
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43. Ayadi-Kaddour A, Ismail O, Hassen F, Smati B, Djilani H, Kilani T, El Mezni F: [Benign mature teratomas of the mediastinum]. Rev Mal Respir; 2008 May;25(5):531-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign mature teratomas of the mediastinum].
  • [Transliterated title] Tératomes matures bénins du médiastin.
  • INTRODUCTION: Mature teratomas of the mediastinum are rare.
  • However, they represent the most common mediastinal germ cell tumours.
  • PATIENTS AND METHODS: Fourteen cases of mediastinal mature teratoma, diagnosed between January 1992 and December 2006, were reviewed retrospectively, noting the clinical, radiological, surgical, and pathological findings.
  • Imaging features comprised a heterogeneous anterior mediastinal mass containing soft-tissue, fluid, fat, or calcium attenuation, or any combination of the four.
  • CONCLUSION: Every form of teratoma occurs in the mediastinum (mature, immature and with malignant transformation) but, in our study, they were exclusively mature.
  • However, pancreatic tissue occurs frequently in mediastinum (54% in literature, 25% in our study) but not in the gonads.
  • On the other hand, thyroid follicles have not yet been seen in mediastinal teratomas.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 18535520.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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44. Bastos P, Magalhães A, Fernandes G, Cruz MR, Saleiro S, Gonçalves L, Piñon M: [Primary cysts and tumors of the mediastinum]. Rev Port Pneumol; 2007 Sep-Oct;13(5):659-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary cysts and tumors of the mediastinum].
  • [Transliterated title] Cistos e tumores primários do mediastino.
  • OBJECTIVE: To assess results in patients with primary cysts and tumours of the mediastinum who under- went surgery.
  • METHODS: A retrospective single-centre study was undertaken into patients with primary cysts and tumours of the mediastinum who underwent surgery between January 1992 and December 2004.
  • We analysed demographic data, clinical presentation, type of surgery carried out and procedure, lesion location and histological diagnosis.
  • The pri- mary tumours included thymic neoplasms (31%), lymphoma (22%), neurogenic tumours (16%), germ cell tumours (9%) and a miscellaneous group (13%).
  • Malignant neoplasms were present in 78 patients (46%).
  • The antero-superior mediastinum was the most commonly involved site to have a primary cyst or tumour (58%), followed by the posterior mediastinum (24%) and the middle mediastinum (18%).
  • Actuarial survival at five years was 97.6% for benign lesions and 76.4% for malignant tumours.
  • CONCLUSION: Results support surgical resection for benign lesions and an aggressive multimodal approach for malignant tumours.
  • [MeSH-major] Mediastinal Cyst / surgery. Mediastinal Neoplasms / surgery

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  • (PMID = 17962885.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
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45. Doğan R, Kara M, Yazicioğlu A, Onder S: Giant atypical lipomatous tumor of the mediastinum. Tuberk Toraks; 2008;56(1):100-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant atypical lipomatous tumor of the mediastinum.
  • Mediastinum is an uncommon localization for these tumors and they have a potential risk of recurrence following excision.
  • We herein report a case with a giant atypical lipomatous tumor located at the mediastinum that was surgically excised.
  • Surgery remains as the treatment of choice for mediastinal liposarcomas.
  • [MeSH-major] Liposarcoma / surgery. Mediastinal Neoplasms / surgery

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  • (PMID = 18330763.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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46. Paul S, Jain SH, Gallegos RP, Aranki SF, Bueno R: Functional paraganglioma of the middle mediastinum. Ann Thorac Surg; 2007 Jun;83(6):e14-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional paraganglioma of the middle mediastinum.
  • We describe a 49-year-old woman with refractory hypertension resulting from a functional paraganglioma of the middle mediastinum.
  • We believe that this is the first report of a functionally active paraganglioma of the mediastinum requiring resection with cardiopulmonary bypass and aortic reconstruction.
  • [MeSH-major] Aorta / surgery. Mediastinal Neoplasms / surgery. Paraganglioma / surgery

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  • (PMID = 17532372.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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47. Joshi S, Haridas A, Rout PL: Primary carcinoid of posterior mediastinum: truth or myth! Indian J Chest Dis Allied Sci; 2010 Oct-Dec;52(4):241-3
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary carcinoid of posterior mediastinum: truth or myth!
  • Mediastinal masses present challenging problems in thoracic practice.
  • Carcinoids arising from the mediastinum are invariably related to thymus.
  • Non-thymic origin of mediastinal carcinoids is rare, especially in the posterior mediastinum.
  • Only two cases of posterior mediastinal carcinoids have been reported so far.
  • We report a case of a 45-year-old woman who presented with dyspnoea and dry cough due to giant carcinoid tumour of the mediastinum, the pedicle originating from the posterior mediastinum, not related to thymus.
  • The immunochemical studies revealed positive reaction to cytokeratin, chromogranins and synaptophysin, and negative reaction to S100, CD99 (MIC2) confirming the tumour being neuroendocrine in nature.
  • [MeSH-major] Carcinoid Tumor / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 21302602.001).
  • [ISSN] 0377-9343
  • [Journal-full-title] The Indian journal of chest diseases & allied sciences
  • [ISO-abbreviation] Indian J Chest Dis Allied Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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48. Veselý M, Pestál A, Dolezel J, Jedlicka V, Capov I, Chovanec Z, Veverková L, Hermanová M: [Malignant mediastinal teratoma--a case review]. Rozhl Chir; 2009 May;88(5):222-4
Genetic Alliance. consumer health - Teratoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant mediastinal teratoma--a case review].
  • [Transliterated title] Maligni teratom mediastina--kazuistika.
  • In this case report the authors present a case of mediastinal malignant teratoma of a 23 years old patient, who suddenly suffers form chest pain as the only symptom.
  • During examination is a huge mediastinal tumor diagnosed.
  • After histological diagnosis is a radical surgery performed.
  • The aim of our report is to think always about the mediastinal tumors as one of the possible cause of thoracic pain.
  • [MeSH-major] Mediastinal Neoplasms. Teratoma

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  • (PMID = 19642337.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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49. Mahmoud A, Pham H, Matolo N, Shrivastava D: Safety of mediastinoscopy in anatomical variations of the mediastinum: the situs inversus syndrome. Am Surg; 2006 Jan;72(1):64-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Safety of mediastinoscopy in anatomical variations of the mediastinum: the situs inversus syndrome.
  • Mediastinoscopy has been widely used by thoracic surgeons to evaluate the superior mediastinum since 1959.
  • Proper attention to surgical techniques and mediastinal anatomy are essential to maintain the safety of the procedure.
  • Situs inversus totalis is exceedingly rare, but variations in mediastinal anatomy in this group of patients can render the procedure challenging for the thoracic surgeon.
  • A case of mediastinoscopy in a situs inversus patient is presented with emphasis on anatomical variations of the mediastinum and technical pitfalls of the procedure in this rare group.
  • [MeSH-major] Mediastinoscopy / methods. Mediastinum / anatomy & histology. Situs Inversus / diagnosis

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  • (PMID = 16494186.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Choe KS, Salama JK: Advances in radiotherapy for tumors involving the mediastinum. Thorac Surg Clin; 2009 Feb;19(1):133-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advances in radiotherapy for tumors involving the mediastinum.
  • RT is an integral component of treatment in many tumors of the mediastinum.
  • [MeSH-major] Mediastinal Neoplasms / radiotherapy
  • [MeSH-minor] Carbon Radioisotopes / therapeutic use. Carcinoma, Non-Small-Cell Lung / radiotherapy. Humans. Lymphoma / radiotherapy. Radiotherapy / methods. Radiotherapy Planning, Computer-Assisted. Small Cell Lung Carcinoma / radiotherapy. Thymoma / radiotherapy. Thymus Neoplasms / radiotherapy

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  • (PMID = 19288828.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbon Radioisotopes
  • [Number-of-references] 60
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56. Weissenbacher A, Bodner J: Robotic surgery of the mediastinum. Thorac Surg Clin; 2010 May;20(2):331-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Robotic surgery of the mediastinum.
  • Several different mediastinal procedures for benign and malignant diseases have been proved to be feasible and safe when performed by a robotic minimally invasive approach.
  • This article reviews the published data on robotic mediastinal surgery, focusing on technical aspects and perioperative outcomes.
  • Is there a need for the robot in the mediastinum?
  • [MeSH-major] Mediastinal Diseases / surgery. Robotics. Thoracic Surgical Procedures / methods

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20451142.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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57. Guimarães MJ, Valente CM, Santos L, Baganha MF: Ectopic thyroid in the anterior mediastinum. J Bras Pneumol; 2009 Apr;35(4):383-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic thyroid in the anterior mediastinum.
  • Ectopic thyroid is a rare condition, and its location in the anterior mediastinum is even rarer, there having been only 5 reported cases in the past 30 years.
  • [MeSH-major] Choristoma / diagnosis. Mediastinal Diseases / diagnosis. Thyroid Gland
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Mediastinal Neoplasms / diagnosis. Middle Aged

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  • (PMID = 19466277.001).
  • [ISSN] 1806-3756
  • [Journal-full-title] Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • [ISO-abbreviation] J Bras Pneumol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 18
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58. De Troyer A: Impact of diaphragmatic contraction on the stiffness of the canine mediastinum. J Appl Physiol (1985); 2008 Sep;105(3):887-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of diaphragmatic contraction on the stiffness of the canine mediastinum.
  • Thus, although the canine ventral mediastinum is a delicate structure, it sustained a significant pressure gradient.
  • The hypothesis was then considered that this gradient was allowed to develop through the stretching and stiffening of the mediastinum caused by the descent of the diaphragm, and it was tested by measuring DeltaPao in the two lungs during isolated, unilateral contraction of the inspiratory intercostal muscles.
  • A model analysis of the respiratory system led to the estimate that mediastinal elastance was approximately 25 times greater during hemidiaphragmatic contraction than during unilateral intercostal contraction.
  • These observations indicate that 1) a particular hemidiaphragm has an expanding action on both lungs and 2) during contraction, however, it makes the mediastinum stiffer so that the pressure transmission from the ipsilateral to the contralateral pleural cavity is reduced.
  • These observations imply that the mediastinum may play a significant role in determining the pressure-generating ability of the diaphragm.
  • [MeSH-major] Diaphragm / physiology. Inhalation. Lung / physiology. Mediastinum / physiology. Muscle Contraction

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  • (PMID = 18635883.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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59. Migliore M, Costanzo M, Cannizzaro MA: Cervico-mediastinal goiter: is telescopic exploration of the mediastinum (video mediastinoscopy) useful? Interact Cardiovasc Thorac Surg; 2010 Mar;10(3):439-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cervico-mediastinal goiter: is telescopic exploration of the mediastinum (video mediastinoscopy) useful?
  • Surgeons are aware that most mediastinal goiters can be excised through a Kocher transverse collar incision, but in rare circumstances a partial-complete median sternotomy or a thoracotomy are mandatory.
  • During an operation to remove a large cervico-mediastinal goiter (CMG) a profound, not massive, bleeding in the anterior mediastinum developed.
  • Telescopic exploration of the mediastinum was performed in seven patients.
  • The goiters were located in the middle mediastinum in five patients and in the anterior and middle mediastinum in one, respectively.
  • The use of a telescope can help the surgeon during the removal of a large mediastinal goiter.

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  • (PMID = 20022881.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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60. Bhatnagar S, Pradhan R, Shastri P, Shenoy P: Accessory thymus in posterior mediastinum. J Indian Assoc Pediatr Surg; 2008 Oct;13(4):140-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Accessory thymus in posterior mediastinum.
  • Presence of thymus in the normal position as well as in the posterior mediastinum is an unusual phenomenon.
  • We report here a case of posterior mediastinal mass in a 20-month old male child who presented with dysphagia and dry cough.
  • Investigations revealed it to be a solid posterior mediastinal mass, suspected to be either lymphoma or a neuroblastoma.
  • This case indicates that a benign mass, an accessory thymus, though rare, can be located in the posterior mediastinum and cause symptoms similar to solid mediastinal tumors.

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  • [Cites] Pediatr Radiol. 1978 Dec 4;7(4):243-4 [733404.001]
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  • (PMID = 20011497.001).
  • [ISSN] 1998-3891
  • [Journal-full-title] Journal of Indian Association of Pediatric Surgeons
  • [ISO-abbreviation] J Indian Assoc Pediatr Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2788476
  • [Keywords] NOTNLM ; Accessory thymus / posterior mediastinum
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61. D'Andrilli A, Venuta F, Rendina EA: Surgical approaches for invasive tumors of the anterior mediastinum. Thorac Surg Clin; 2010 May;20(2):265-84

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical approaches for invasive tumors of the anterior mediastinum.
  • Malignant tumors of the anterior mediastinum frequently appear locally advanced at the time of diagnosis, with invasion of the surrounding organs including major blood vessels, lungs, and pericardium.
  • Extended operations with complex vascular reconstructions may be required for the complete removal of the mediastinal mass.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Thoracic Surgical Procedures / methods
  • [MeSH-minor] Combined Modality Therapy. Humans. Mediastinoscopy / methods. Neoplasm Invasiveness. Reconstructive Surgical Procedures / methods. Sternotomy. Thoracic Surgery, Video-Assisted / methods. Vena Cava, Superior / surgery

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20451137.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 46
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62. Kitano K, Konoeda C, Tanaka M: [Multiple presentation of undifferentiated pleomorphic sarcoma in the mediastinum]. Kyobu Geka; 2010 Nov;63(12):1045-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multiple presentation of undifferentiated pleomorphic sarcoma in the mediastinum].
  • A case of undifferentiated pleomorphic sarcoma in the mediastinum is presented.
  • A 74-year-old man with no complaint was referred to our department for treatment of mediastinal mass pointed out by chest X-ray.
  • Chest computed tomography (CT) revealed 3 tumors located in the left mediastinum.
  • A diagnosis of undifferentiated pleomorphic sarcoma was made with negative immunohistochemical staining for markers except for vimentin.
  • Tumor cells were found to be scattered in the partially resected thymus.
  • We assume this is a rare presentation of mediastinal dissemination of the tumor.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Mediastinal Neoplasms / pathology

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  • (PMID = 21066845.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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63. Limmer S, Merz H, Kujath P: Giant thymoma in the anterior-inferior mediastinum. Interact Cardiovasc Thorac Surg; 2010 Mar;10(3):451-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant thymoma in the anterior-inferior mediastinum.
  • Thymomas are usually found in the superior mediastinum and sternotomy is the standard approach for resection.
  • Due to the sheer size of the tumor and its location in the anterior-inferior mediastinum, we performed a lateral approach for thymectomy.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis. Thymoma / diagnosis. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Thymectomy. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20040475.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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64. De Raet J, Sacré R, Hoorens A, Fletcher C, Lamote J: Malignant giant solitary fibrous tumor of the mediastinum. J Thorac Oncol; 2008 Sep;3(9):1068-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant giant solitary fibrous tumor of the mediastinum.
  • Malignant giant solitary fibrous tumor (SFT) of the mediastinum is a rare neoplasm derived from mesenchymal tissue.
  • Owing to its large size, a complete resection of the tumor can present many challenges, particularly given its proximity to vital neighboring structures.
  • We report a successful en-bloc resection of a massive mediastinal SFT, which was compressing the inferior trachea and heart, by means of a median sternotomy and an anterior left thoracotomy.
  • We emphasize the rarity of this uncommon mediastinal mass.
  • Key points of mediastinal SFT are discussed.
  • [MeSH-major] Mediastinal Neoplasms / pathology. Solitary Fibrous Tumors / pathology. Thoracotomy

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  • (PMID = 18758314.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Rivo JE, Cañizares MA, García-Fontán E, Albort J, González-Piñeiro A, Peñalver R: [Liposarcomas of the mediastinum in atypical locations: report of two cases]. Cir Esp; 2005 Feb;77(2):99-101

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Liposarcomas of the mediastinum in atypical locations: report of two cases].
  • [Transliterated title] Liposarcomas mediastínicos de localización atípica. Aportación de 2 casos.
  • Liposarcomas of the mediastinum are unusual tumors characterized by compression of neighboring structures and frequent recurrence.
  • Computed tomography and magnetic resonance imaging provide useful data for diagnosis.
  • We report two cases of mediastinal liposarcoma: the first was a liposarcoma that was a recurrence of an atypical lipoma of the neck, and the second was a giant mediastinal liposarcoma involving both hemithoraces.
  • [MeSH-major] Liposarcoma / diagnosis. Mediastinal Neoplasms / diagnosis

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  • (PMID = 16420896.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 7
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66. Shoji F, Maruyama R, Okamoto T, Wataya H, Nishiyama K, Ichinose Y: Malignant schwannoma of the upper mediastinum originating from the vagus nerve. World J Surg Oncol; 2005 Oct 6;3:65

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant schwannoma of the upper mediastinum originating from the vagus nerve.
  • BACKGROUND: Malignant schwannoma of the upper mediastinum originating from the vagus nerve is extremely rare.
  • Chest computed tomography showed a mass extending from the left upper mediastinum to the left supraclavicular area.
  • The tumor was found to involve both the left vagus nerve and the left sympathetic nerve.
  • Histological examination of the resected specimen revealed the tumor to be malignant schwannoma.
  • CONCLUSION: Despite incorrect preoperative diagnosis, the multimodality treatment administered in this case, including induction chemo-radiotherapy and surgery, proved to be effective.

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  • [Cites] Ann Thorac Surg. 2003 Dec;76(6):1810-4; discussion 1815 [14667588.001]
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  • (PMID = 16207383.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1276821
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67. Kaplan T, Altuntas B, Ceran S, Sadi Sunam G: Unusual location of arteriovenous malformation; posterior mediastinum. Interact Cardiovasc Thorac Surg; 2009 Feb;8(2):260-2
MedlinePlus Health Information. consumer health - Arteriovenous Malformations.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual location of arteriovenous malformation; posterior mediastinum.
  • Vascular malformations of the mediastinum presenting as mediastinal masses are very rare.
  • We report a histologically proven case of a posterior mediastinal arteriovenous malformation in a 42-year-old man that was incidentally detected by chest radiography during a routine health check.
  • [MeSH-major] Arteriovenous Malformations / pathology. Diagnostic Errors. Echinococcosis / diagnosis. Incidental Findings. Mediastinal Cyst / diagnosis. Mediastinum / blood supply

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  • (PMID = 19038980.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 10
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68. Milosavljević MZ, Mitrović SLj, Vujadinović M, Aćimović L, Mrvić SA, Milisavljević SS: Giant dumbbell tumor of the posterior mediastinum. Vojnosanit Pregl; 2009 Nov;66(11):909-13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant dumbbell tumor of the posterior mediastinum.
  • CASE REPORT: We presented a 54-year-old woman with a giant dumbbell schwannoma in the posterior mediastinum.
  • The tumor was removed by the posterior approach with hemilaminectomy and costotransversectomy.
  • By microscopic examination the diagnosis of benign schwannoma was made.
  • [MeSH-major] Mediastinal Neoplasms / pathology. Neurilemmoma / pathology

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  • (PMID = 20017423.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
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69. Geusens E, Pans S, Prinsloo J, Fourneau I: The widened mediastinum in trauma patients. Eur J Emerg Med; 2005 Aug;12(4):179-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The widened mediastinum in trauma patients.
  • Mediastinal widening is a frequent radiological finding in the emergency department patient.
  • The causes of mediastinal widening can be divided into traumatic and nontraumatic mediastinal widening.
  • An important association of moderate to high velocity trauma is the mediastinal haematoma.
  • It may be the result of traumatic transsection of the aorta, or it may be due to bleeding from other mediastinal vessels.
  • Before the era of multidetector spiral CT, angiography was the gold standard for the evaluation of patients with a widened mediastinum.
  • This article discusses the radiological signs of traumatic mediastinal widening.
  • Different traumatic lesions resulting in a widened mediastinum are presented, and some nontraumatic causes of a widened mediastinum are shown, in order to facilitate the differentiation between both entities.
  • [MeSH-major] Hematoma / radiography. Mediastinum / radiography. Wounds and Injuries / radiography

  • MedlinePlus Health Information. consumer health - Wounds and Injuries.
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  • (PMID = 16034263.001).
  • [ISSN] 0969-9546
  • [Journal-full-title] European journal of emergency medicine : official journal of the European Society for Emergency Medicine
  • [ISO-abbreviation] Eur J Emerg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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70. Ciriaco P, Negri G, Bandiera A, Casiraghi M, Ferla L, Torracca L, Zannini P: Videothoracoscopic resection of benign neurogenic tumors of the posterior mediastinum. Innovations (Phila); 2006;1(6):332-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Videothoracoscopic resection of benign neurogenic tumors of the posterior mediastinum.
  • OBJECTIVE: : Videothoracoscopy is becoming the preferred approach for the removal of neurogenic mediastinal tumors.
  • The aim of the study was to evaluate the feasibility of videothoracoscopic resection of benign neurogenic tumors (BNT) of the posterior mediastinum, including dumbbell-type tumors, through a retrospective review of our experience.
  • METHODS: : Between January 1993 and November 2005, 30 patients underwent resection of a BNT of the posterior mediastinum at our institution.
  • Preoperative assessment included chest CT scan, nuclear magnetic resonance for dumbbell-type tumors, and spinal angiography when the tumor was located in the vicinity of the Adamkiewicz artery.
  • RESULTS: : Mean tumor size was 5.6 ± 1.4 cm (range, 4 to 11).
  • CONCLUSIONS: : BNT of the posterior mediastinum, including dumbbell-type tumors, can be safely resected thoracoscopically.

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  • (PMID = 22436834.001).
  • [ISSN] 1556-9845
  • [Journal-full-title] Innovations (Philadelphia, Pa.)
  • [ISO-abbreviation] Innovations (Phila)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Machaladze ZO, Davydov MI, Polotskiĭ BE, Karseladze AI, Savelov NA: [Surgery for mesenchymal tumours of the mediastinum]. Khirurgiia (Mosk); 2008;(4):43-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgery for mesenchymal tumours of the mediastinum].
  • Results of treatment of 52 patients with mesenchymal tumours of the mediastinum.
  • Among 52 patients with mesenchymal tumours of the mediastinum, 40 patients were treated surgically and 12 patients got conservative treatment.
  • Radical surgical treatment was carried out in 21 patients with benign tumors.
  • Benign tumors have a favorable prognosis after surgical treatment.
  • Major factors of the prognosis of surgical treatment are dissemination and the histologic form of a tumor as well as type of surgical intervention.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Mediastinoscopy / methods. Mesenchymoma / surgery. Thoracic Surgery, Video-Assisted / methods

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  • (PMID = 18454108.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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72. Orki A, Patlakoglu MS, Tahaoglu C, Kutlu CA: Malignant invasive thymoma in the posterior mediastinum. Ann Thorac Surg; 2009 Apr;87(4):1274-5
MedlinePlus Health Information. consumer health - Thymus Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant invasive thymoma in the posterior mediastinum.
  • We present a rare case of malignant invasive thymoma (type A) arising from the posterior mediastinum.
  • The tumor and parenchymal foci were totally resected through a left minithoracotomy.
  • [MeSH-major] Thymoma / therapy. Thymus Neoplasms / therapy
  • [MeSH-minor] Adolescent. Female. Humans. Mediastinum. Thoracic Surgery, Video-Assisted

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  • (PMID = 19324171.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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73. Huang YX, Jin LZ, Lowe JA, Wang XY, Xu HZ, Teng YJ, Zhang HZ, Chi YL: Three-dimensional reconstruction of the superior mediastinum from Chinese Visible Human Female. Surg Radiol Anat; 2010 Aug;32(7):693-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Three-dimensional reconstruction of the superior mediastinum from Chinese Visible Human Female.
  • PURPOSE: This research aimed to construct three-dimensional (3D) visible models of the superior mediastinum for anatomic study and surgical approaches to the superior mediastinum.
  • METHOD: Sectional images of the superior mediastinum were acquired through the Chinese Visible Human Female (VCHF) database.
  • One hundred eighty images of the superior mediastinum were imported into Photoshop CS and the images were converted into a JPEG format.
  • RESULT: The surface and volume reconstruction of the superior mediastinum were successful.
  • The surface reconstruction model allowed rotation and magnification of the superior mediastinum structures as well as displayed the contours of reconstructed structures individually or as a composite with any other selected structure.
  • CONCLUSION: Three-dimensional, visible models of the superior mediastinum based on the sectional images of VCHF can provide unique insight into the anatomy of superior mediastinum.
  • [MeSH-major] Image Processing, Computer-Assisted / methods. Imaging, Three-Dimensional. Mediastinum / anatomy & histology. Visible Human Projects

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  • (PMID = 20131053.001).
  • [ISSN] 1279-8517
  • [Journal-full-title] Surgical and radiologic anatomy : SRA
  • [ISO-abbreviation] Surg Radiol Anat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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74. Shadmehr MB, Jamaati HR, Saidi B, Tehrai M, Arab M: Extralobar sequestration in anterior mediastinum with pericardial agenesis. Ann Thorac Surg; 2009 Jul;88(1):291-3
MedlinePlus Health Information. consumer health - Thymus Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extralobar sequestration in anterior mediastinum with pericardial agenesis.
  • A computed tomographic (CT) scan demonstrated an anterior mediastinal mass.
  • The anterior mediastinum is an unusual site for extralobar sequestions.
  • It is recommended to include extralobar sequestration in the differential diagnosis of anterior mediastinal masses, even if the aberrant artery is not recognized on the computed tomographic scan.
  • [MeSH-major] Bronchopulmonary Sequestration / surgery. Mediastinum / surgery. Pericardium / abnormalities. Thoracic Surgical Procedures / methods. Thymoma / diagnosis. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Abnormalities, Multiple / radiography. Abnormalities, Multiple / surgery. Angiography. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Rare Diseases. Risk Assessment. Sternum / surgery. Thoracotomy / methods. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • (PMID = 19559252.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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75. Tamura Y, Takahama M, Kushibe K, Taniguchi S: Ectopic pancreas in the anterior mediastinum. Jpn J Thorac Cardiovasc Surg; 2005 Sep;53(9):498-501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic pancreas in the anterior mediastinum.
  • We report an uncommon clinical case of anterior mediastinal localization of ectopic pancreatic tissue.
  • A 39-year-old male was referred to our institution for investigation of an abnormal mediastinal shadow on a chest X-ray, and a large cystic lesion measuring 10 x 8 cm located in the anterior mediastinum was observed on a computed tomographic scan.
  • The postoperative pathological examination confirmed the diagnosis of ectopic mediastinal pancreas.
  • [MeSH-major] Choristoma / diagnosis. Mediastinal Diseases / diagnosis. Pancreas

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  • (PMID = 16200892.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
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76. Martino F, Avila LF, Encinas JL, Luis AL, Olivares P, Lassaletta L, Nistal M, Tovar JA: Teratomas of the neck and mediastinum in children. Pediatr Surg Int; 2006 Aug;22(8):627-34
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Teratomas of the neck and mediastinum in children.
  • This retrospective study reviews a series of teratomas of the neck and mediastinum aiming at defining the features of these particular locations.
  • We recorded prenatal diagnosis, perinatal management, clinical and radiologic features, pathology, surgical strategies and results in cervical and mediastinal teratomas treated over the last 10 years.
  • Five babies had cervical teratomas extended into the anterior mediastinum in two cases.
  • Prenatal diagnosis was made in three (two with polyhydramnios).
  • The diagnosis was confirmed by imaging and increased AFP.
  • Surgical treatment involved total tumor removal and in one case subsequent removal of lymph node metastases.
  • During the same period six patients aged 0-17 years were treated for mediastinal teratoma.
  • Prenatal diagnosis and planned multidisciplinary management are mandatory at birth.
  • In contrast, only some mediastinal tumors cause respiratory embarrassment.
  • Although benign, these tumors are sometimes immature and may metastasize to regional lymph nodes.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / surgery. Mediastinal Neoplasms / diagnosis. Mediastinal Neoplasms / surgery. Teratoma / diagnosis. Teratoma / surgery
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Fetal Diseases / surgery. Humans. Infant. Infant, Newborn. Male. Pregnancy. Prenatal Diagnosis. Retrospective Studies

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  • (PMID = 16838188.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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77. Suehisa H, Yamashita M, Komori E, Sawada S, Teramoto N: Solitary fibrous tumor of the mediastinum. Gen Thorac Cardiovasc Surg; 2010 Apr;58(4):205-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the mediastinum.
  • An 18-year-old man was referred to our hospital for further evaluation of a right anterior mediastinal tumor that measured 6 cm in diameter.
  • Computed tomography-guided transcutaneous aspiration biopsy was performed, but no definitive diagnosis could be obtained.
  • Because the tumor did not appear to be a high-grade malignant tumor, we undertook resection of the tumor to obtain a definitive diagnosis and provide appropriate treatment.
  • Total thymectomy with tumor resection was performed through a median sternotomy.
  • The tumor was solid, measuring 5.2 x 4.2 x 3.5 cm.
  • The histological diagnosis was solitary fibrous tumor (SFT) arising from the mediastinum.
  • Most extrathoracic SFTs appear to pursue a benign course, although careful long-term follow-up of these patients is necessary because the tumors have been reported to recur or metastasize in some cases.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis. Solitary Fibrous Tumors / diagnosis

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  • (PMID = 20401717.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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78. Thomas-de-Montpréville V, Dulmet E: Cysts of the posterior mediastinum showing müllerian differentiation (Hattori's cysts). Ann Diagn Pathol; 2007 Dec;11(6):417-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cysts of the posterior mediastinum showing müllerian differentiation (Hattori's cysts).
  • Cysts of probable müllerian origin have recently been recognized in the mediastinum by Hattori (Virchows Arch.
  • In a retrospective study, we found 9 such cases, accounting for 5.5% of a series of 163 consecutive mediastinal nonneoplastic cysts operated in our institution.
  • They were initially classified as bronchogenic or unspecified benign serous cysts.
  • In conclusion, cysts with müllerian differentiation account for a small proportion of mediastinal cysts and have a usual but nonspecific paravertebral location.
  • [MeSH-major] Mediastinal Cyst / pathology. Mullerian Ducts / pathology
  • [MeSH-minor] Adult. Female. Humans. Hysterectomy. Immunohistochemistry. Leiomyoma / complications. Leiomyoma / surgery. Middle Aged. Mucin-1 / metabolism. Obesity / complications. Ovarian Cysts / complications. Ovarian Cysts / surgery. Polyps / complications. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Retrospective Studies. Uterine Cervical Neoplasms / complications. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18022126.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucin-1; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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79. Estrozi B, Queiroga E, Bacchi CE, Faria Soares de Almeida V, Lucas de Carvalho J, Lageman GM, Rosado-de-Christenson M, Suster S: Myxopapillary ependymoma of the posterior mediastinum. Ann Diagn Pathol; 2006 Oct;10(5):283-7
Genetic Alliance. consumer health - Myxopapillary ependymoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxopapillary ependymoma of the posterior mediastinum.
  • It was not possible to determine the exact anatomic location of the mass based on the imaging studies as both peripheral lung tumors and posterior mediastinal lesions may exhibit the imaging findings described here.
  • At thoracotomy, the mass was seen to be well circumscribed, focally attached to the pleura but without involvement of lung parenchyma, and situated in the left posterior mediastinum.
  • Immunohistochemical studies confirmed this impression by demonstrating strong positivity of the tumor cells for S-100 protein, glial fibrillary acidic protein, and CD99 and negative staining with other differentiation markers.
  • A review of the literature with a discussion of the histologic and radiologic differential diagnosis of these lesions is presented.
  • [MeSH-major] Ependymoma / pathology. Mediastinal Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD / genetics. Antigens, CD / metabolism. Cell Adhesion Molecules / genetics. Cell Adhesion Molecules / metabolism. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Glial Fibrillary Acidic Protein / genetics. Glial Fibrillary Acidic Protein / metabolism. Humans. S100 Proteins / genetics. S100 Proteins / metabolism. Tomography, X-Ray Computed

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  • (PMID = 16979521.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins
  • [Number-of-references] 24
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80. De Troyer A, Cappello M, Leduc D, Gevenois PA: Role of the mediastinum in the mechanics of the canine diaphragm. J Appl Physiol (1985); 2010 Jul;109(1):27-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of the mediastinum in the mechanics of the canine diaphragm.
  • The objective of this study was to evaluate the role of the mediastinum in the mechanics of the canine diaphragm.
  • In the first experiment on five animals, the mediastinum was severed from the sternum to the vena cava, and radiopaque markers were attached to muscle bundles in the midcostal region of the diaphragm.
  • From these data, accurate measurements of muscle displacement and muscle length were obtained, and these measurements, together with the changes in airway opening pressure, were compared with those previously obtained in animals with an intact mediastinum.
  • Severing the mediastinum per se appeared to have no influence on the pressure-generating capacity of the diaphragm or on the lung-volume dependence of this capacity.
  • In the second experiment, therefore, loads were applied caudally to the central tendon to assess the force-displacement relationship of the entire mediastinum, and this relationship, combined with the known displacement of the diaphragm dome during phrenic nerve stimulation, was used to infer the force exerted by the mediastinum on the muscle during contraction.
  • It is concluded, therefore, that the mediastinum has only little influence on the mechanics of the canine diaphragm.
  • [MeSH-major] Diaphragm / physiology. Mediastinum / physiology. Respiratory Mechanics / physiology

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  • (PMID = 20448030.001).
  • [ISSN] 1522-1601
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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81. Dutta R, Kumar A, Jindal T, Tanveer N: Concurrent benign schwannoma of oesophagus and posterior mediastinum. Interact Cardiovasc Thorac Surg; 2009 Dec;9(6):1032-4
MedlinePlus Health Information. consumer health - Esophageal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent benign schwannoma of oesophagus and posterior mediastinum.
  • A 52-year-old female with recent onset dysphagia and haematemesis was found to have an intramural tumour of the oesophagus.
  • A separate tumour in the posterior mediastinum was also detected.
  • Both the tumours were immunohistochemically and histomorphologically compatible with benign schwannoma.
  • Oesophageal schwannoma is extremely rare and its association with a concurrent schwannoma in posterior mediastinum is not reported earlier in the literature.
  • [MeSH-major] Esophageal Neoplasms / diagnosis. Mediastinal Neoplasms / diagnosis. Neoplasms, Multiple Primary. Neurilemmoma / diagnosis

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  • (PMID = 19770133.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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82. Hsu JS, Kang WY, Chou SH, Chuang MT: Mature cystic teratoma in the anterior mediastinum containing a carcinoid. J Thorac Imaging; 2006 Mar;21(1):60-2
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mature cystic teratoma in the anterior mediastinum containing a carcinoid.
  • Mature teratomas are common neoplasms in the anterior mediastinum.
  • However, a primary carcinoid tumor occurring in a mature teratoma is extremely rare.
  • To our knowledge, there are only 2 published articles in the literature to date reporting a mature cystic teratoma of the mediastinum containing a carcinoid.
  • We herein report another case of primary carcinoid tumor arising from a mature cystic teratoma in the anterior mediastinum.
  • [MeSH-major] Carcinoid Tumor / diagnosis. Mediastinal Neoplasms / diagnosis. Mediastinum / radiography. Neoplasms, Second Primary / diagnosis. Teratoma / diagnosis

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  • (PMID = 16538161.001).
  • [ISSN] 0883-5993
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Sakurai H, Kaji M, Suemasu K: Thymoma of the middle mediastinum: 11C-acetate positron emission tomography imaging. Ann Thorac Surg; 2009 Apr;87(4):1271-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thymoma of the middle mediastinum: 11C-acetate positron emission tomography imaging.
  • Thymomas arising outside the anterior mediastinum are very rare.
  • We report a case of thymoma in the middle mediastinum, right paratracheal region.
  • There have been few reports of middle mediastinal thymoma.
  • In the present case, (11)C-acetate positron emission tomography (PET) was useful for a preoperative suggestive diagnosis.
  • [MeSH-major] Positron-Emission Tomography. Thymoma / radionuclide imaging. Thymus Neoplasms / radionuclide imaging
  • [MeSH-minor] Acetates. Carbon Radioisotopes. Fluorodeoxyglucose F18. Humans. Male. Mediastinum. Middle Aged. Radiopharmaceuticals

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  • (PMID = 19324170.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Acetates; 0 / Carbon Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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84. Fatimi S, Sheikh S, Shafiq M, Shah Z: Non-clostridial gas gangrene of the neck and mediastinum. Asian Cardiovasc Thorac Ann; 2007 Jan;15(1):e12-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-clostridial gas gangrene of the neck and mediastinum.
  • Herein we report a case of gas gangrene of the neck and mediastinum in a poorly managed Type II diabetic with concomitant chronic renal failure and a recent history of mucormycosis.
  • [MeSH-minor] Female. Humans. Mediastinum. Middle Aged. Neck

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  • (PMID = 17244906.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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85. Eckardt J: Endobronchial ultrasound-guided transbronchial needle aspiration of lesions in mediastinum. J Thorac Dis; 2010 Sep;2(3):125-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endobronchial ultrasound-guided transbronchial needle aspiration of lesions in mediastinum.
  • BACKGROUND: Lesions in mediastinum can represent malignancy and warrants further workup.
  • Commonly a diagnosis is achieved by conventional bronchoscopy, transbronchial needle aspiration or CT guided fine needle aspiration, however a number of patients remain undiagnosed despite these common investigations METHODS: During a period of 36 months 601 patients underwent EBUS at our institution.
  • Two hundred ninety three patients had an established diagnosis of lung cancer and were referred to us for mediastinal staging.
  • The remaining patients had a radiologically suspicious intrathoracic lesion of which 107 had an undiagnosed lesion in mediastinum.
  • RESULTS: Of the 107 patients with undiagnosed lesions in the mediastinum 89 enlarged lymph nodes and 18 mediastinal tumours.
  • Forty-eight of the 89 patients (54%) with enlarged mediastinal lymph nodes were diagnosed by EBUS of the remaining 41 patients 11 went on to more invasive methods.
  • In patients with undiagnosed tumours in mediastinum we achieved a final diagnosis by EBUS in 14 of the 18 patients (78%) and 3 went on to more invasive methods.
  • CONCLUSION: EBUS provides a final diagnosis in 78% of patients with tumour in mediastinum and in more than half of patients with enlarged lymph nodes despite previous workup.

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  • (PMID = 22263032.001).
  • [ISSN] 2077-6624
  • [Journal-full-title] Journal of thoracic disease
  • [ISO-abbreviation] J Thorac Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC3256455
  • [Keywords] NOTNLM ; EBUS / lung cancer / tumour mediastinum
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86. Marulli G, Rea F, Feltracco P, Calabrese F, Giacometti C, Rizzardi G, Vincenzo L, Sartori F: Successful resection of a giant primary liposarcoma of the posterior mediastinum. J Thorac Oncol; 2007 May;2(5):453-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful resection of a giant primary liposarcoma of the posterior mediastinum.
  • Primary liposarcomas of the mediastinum are extremely rare neoplasms, comprising less than 1% of all mediastinal tumors.
  • We present a case involving a successful radical resection of a large myxoid liposarcoma and its recurrence, both located in the posterior mediastinum.
  • [MeSH-major] Liposarcoma / diagnosis. Mediastinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Reoperation. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 17473663.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Uludag M, Isgor A, Yetkin G, Citgez B: Ectopic mediastinal thyroid tissue: cervical or mediastinum originated? BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic mediastinal thyroid tissue: cervical or mediastinum originated?
  • The thyroid mass extended to the mediastinum and was totally extracted by cervical incision.
  • Postoperatively, a residual thyroid mass of 8.5×9×10 cm in size, was detected on MRI at the median part of the anterior mediastinum.
  • The isolated mediastinal thyroid mass was then extracted by sternotomy.
  • We believe that, because of the close anatomical relationship between the thyroid tissue extending cervically and the mass detected in the mediastinum, the mediastinal mass might have developed from the cervical thyroid tissue residues by pushing the cervical thyroid or it might have mechanically entered the mediastinum.

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  • [Cites] Thyroid. 1999 Dec;9(12):1261-4 [10646669.001]
  • [Cites] Ann Chir. 2000 Jan;125(1):18-25 [10921180.001]
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  • (PMID = 21686510.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028393
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88. Lemenev VL, Mikhaĭlov IP, Iofik VV, Zhulin DV, Abakumov MM: [Flap transverse sternotomy during operations on the vessels and organs of the upper mediastinum and the first cervical zone]. Khirurgiia (Mosk); 2005;(10):19-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Flap transverse sternotomy during operations on the vessels and organs of the upper mediastinum and the first cervical zone].
  • A surgical approach to vessels and organs of the upper mediastinum was grounded, developed and tested.
  • [MeSH-major] Aorta, Thoracic / surgery. Brachiocephalic Veins / surgery. Mediastinum / surgery. Sternum / surgery. Surgical Flaps. Thoracotomy / methods

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  • (PMID = 16247402.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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89. Priola SM, Priola AM, Cardinale L, Perotto F, Fava C: The anterior mediastinum: anatomy and imaging procedures. Radiol Med; 2006 Apr;111(3):295-311
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The anterior mediastinum: anatomy and imaging procedures.
  • The mediastinum is divided into compartments (anterior, middle, posterior) on the basis of lateral chest radiographs.
  • Several anatomical and radiological classifications of the mediastinum are reported in the literature.
  • Most mediastinal abnormalities are initially suspected following chest radiography; the need for further investigation and the most appropriate imaging modality are largely dictated by the tentative diagnosis made on this examination.
  • Although routine chest radiography initiates the evaluation of mediastinal disorders, it is rarely diagnostic: notable exceptions are teeth or bones within a mass, which are diagnostic of a teratoma; air/fluid levels suggest an oesophageal origin, hernia, cyst, or abscess.
  • However, even sCT with contrast material is occasionally diagnostic (a confident diagnosis can be made of some lesions such as mature teratoma and mediastinal goiter) but is usually sufficient for preoperative evaluation before mediastinotomy or mediastinoscopy: it is instrumental in planning further diagnostic workup.
  • Besides, although the anterior mediastinum is suitable for sonographic examination, the diagnostic value of ultrasonography has not been fully exploited.
  • The role of fluorodeoxyglucose positron emission tomography (FDG-PET) in mediastinal diseases continues to be evaluated: it has potential for differentiating between benign and malignant disease and is expected to play a more extensive role in the imaging of mediastinal neoplasms in the future.
  • In this paper, the radiological features of masses located in the anterior mediastinum are discussed, with particular reference to radiographic and CT patterns useful to the clinician's everyday practice.
  • [MeSH-major] Diagnostic Imaging. Mediastinal Diseases / diagnosis. Mediastinum / anatomy & histology
  • [MeSH-minor] Contrast Media. Fluorodeoxyglucose F18. Goiter / radiography. Humans. Magnetic Resonance Imaging. Mediastinal Neoplasms / diagnosis. Mediastinal Neoplasms / radiography. Mediastinoscopy. Positron-Emission Tomography. Radiography, Thoracic. Radiopharmaceuticals. Teratoma / radiography. Tomography, Spiral Computed

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  • (PMID = 16683080.001).
  • [ISSN] 0033-8362
  • [Journal-full-title] La Radiologia medica
  • [ISO-abbreviation] Radiol Med
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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90. Wakely PE Jr: Cytopathology-histopathology of the mediastinum II. Mesenchymal, neural, and neuroendocrine neoplasms. Ann Diagn Pathol; 2005 Feb;9(1):24-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytopathology-histopathology of the mediastinum II. Mesenchymal, neural, and neuroendocrine neoplasms.
  • An appraisal of the cytopathology and corresponding histopathology of epithelial, germ cell, and lymphoid lesions of the mediastinum was previously reported in the Journal.
  • This report aims to complete that topic with a discussion focusing on the correlative cyto-histopathology of the major mesenchymal, neural, and neuroendocrine neoplasms from this anatomic site.
  • As previously stated, the mediastinum remains an uncommon site for fine needle aspiration (FNA) biopsy when compared with other anatomic sites.
  • Yet, the recent use of endoscopic ultrasound-guided FNA for sampling mediastinal masses may increase this use.
  • The purpose of this review is to focus on the shared and dissimilar morphologic features of this subset of neoplasms to improve diagnostic correlation between the two.
  • [MeSH-major] Mediastinal Neoplasms / pathology. Mesoderm / pathology. Neoplasms, Fibrous Tissue / pathology. Neoplasms, Nerve Tissue / pathology. Neuroendocrine Tumors / pathology

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  • (PMID = 15692947.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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91. Bhatia V: Endoscopic ultrasound: imaging techniques and applications in the mediastinum. Trop Gastroenterol; 2010 Apr-Jun;30(2 Suppl):S4-19

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic ultrasound: imaging techniques and applications in the mediastinum.
  • The esophagus passes through the superior and posterior mediastinum, and provides a window for transesophageal imaging of the mediastinum.
  • The applications of endosonography in the mediastinum can be divided on the basis of location into:.
  • Primary lung tumours in a periesophageal location and those invading the mediastinum can also be safely biopsied.
  • The most common causes of mediastinal lymphadenopathy are tuberculosis, sarcoidosis, metastatic and reactive.
  • This illustrated review describes the applications of endosonography in the mediastinum, practical tips for optimal imaging, and step-by-step instructions for radial and curved linear array endosonographic imaging, along with relevant applied mediastinal anatomy.
  • [MeSH-major] Endosonography / methods. Mediastinum / ultrasonography
  • [MeSH-minor] Carcinoma, Non-Small-Cell Lung / ultrasonography. Esophageal Neoplasms / ultrasonography. Granular Cell Tumor / ultrasonography. Humans. Leiomyoma / ultrasonography. Lung Neoplasms / ultrasonography. Mediastinal Neoplasms / ultrasonography. Sarcoidosis / ultrasonography. Tuberculosis / ultrasonography

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  • (PMID = 20715425.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 29
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92. Dogan R, Kara M, Firat P, Gedikoglu G: An unusual tumor of the neck and mediastinum: lipoblastomatosis resulting in paraparesis. Eur J Cardiothorac Surg; 2007 Feb;31(2):325-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusual tumor of the neck and mediastinum: lipoblastomatosis resulting in paraparesis.
  • Lipoblastomatous tumors are quite rare neoplasms deriving from embryonic white fatty tissues, most often seen in infancy and childhood.
  • We present a 14-month-old male infant presenting with a mediastinal mass showing paraparesis, who had previously undergone the removal of the cervical part of this mediastinal mass.
  • We removed the mediastinal part of the mass with a posterolateral thoracotomy which proved to be a lipoblastomatosis.
  • We emphasize that this very uncommon tumor located at the neck and mediastinum should be included in the differential diagnosis of infants having gait disturbance.
  • [MeSH-major] Head and Neck Neoplasms / complications. Lipoma / complications. Mediastinal Neoplasms / complications. Paraparesis / etiology. Spinal Cord Compression / etiology

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  • (PMID = 17161954.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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93. Yang C, Liu HP, Chu Y, Liu YH, Wu CY, Ko PJ, Liu HP: Video. Natural orifice transtracheal evaluation of the thoracic cavity and mediastinum. Surg Endosc; 2010 Nov;24(11):2905-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Video. Natural orifice transtracheal evaluation of the thoracic cavity and mediastinum.
  • BACKGROUND: This study aimed to determine the feasibility of a novel transtracheal endoscopic technique for thoracic and mediastinum evaluation in a canine model.
  • METHODS: In two dogs under general anesthesia, a transverse incision was made in the right lateral wall of the lower trachea and used as an entrance for thoracic and mediastinum evaluation.
  • CONCLUSIONS: The transtracheal approach to the thoracic cavity and mediastinum appears to be feasible.

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  • [Cites] Arch Surg. 2007 Aug;142(8):793-6 [17724853.001]
  • [Cites] Endoscopy. 2009 Feb;41(2):154-9 [19214896.001]
  • [Cites] Surg Innov. 2009 Jun;16(2):104-10 [19411279.001]
  • [Cites] Endoscopy. 2009 Jun;41(6):487-92 [19440954.001]
  • (PMID = 20372933.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
  • [Publication-country] Germany
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94. Jung SM, Chu PH, Shiu TF, Wu HH, Kuo TT, Chu JJ, Lin PJ: Expression of OCT4 in the primary germ cell tumors and thymoma in the mediastinum. Appl Immunohistochem Mol Morphol; 2006 Sep;14(3):273-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of OCT4 in the primary germ cell tumors and thymoma in the mediastinum.
  • Primary germ cell tumors (GCTs) and thymoma are both located in the anterior mediastinum.
  • This study examined OCT4 expression in GCTs and thymoma originating from the mediastinum.
  • A retrospective study included 46 consecutive patients with GCTs conducted between 1983 and 2005, and 22 consecutive thymoma in the mediastinum whose tumors had been surgically excised.
  • The 46 primary GCTs in mediastinum included teratoma (n=27; 58.7%), seminoma (n=10; 21.7%), yolk sac tumor (n=6; 13%), embryonal carcinoma (n=1; 2.1%), and mixed GCTs (n=2; 4%; one consisted of teratoma and yolk sac tumor, and the other teratoma, yolk sac tumor, and seminoma); and 22 thymoma including World Health Organization type A (n=3, 13.6%), type AB (n=4, 18.2%), type B1 (n=6, 27.3%), type B2 (n=4, 13.6%), and type B3 (n=5, 22.7%).
  • Each tumor was examined with hematoxylin and eosin staining, and with antibodies to OCT4.
  • On the other hand, the 22 thymoma, 6 yolk sac tumor, 27 teratomas, and 1 case with mixed GCT without component of seminoma were immunonegative for OCT4.
  • We conclude that immunostaining with antibodies to OCT4 is a useful diagnostic tool in the identification of seminomas and primary embryonal carcinomas in GCTs originating from the mediastinum.

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  • (PMID = 16932017.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Congresses; Evaluation Studies; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / OKT4A monoclonal antibody
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95. Wang Z, Zhao Y, Zhou C, Li R, Wu G, Zhao R, Hu J, Chen X, Zhou W: [Discussion about cervical incision of goiter in mediastinum posterior and its indications]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Sep;22(18):817-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Discussion about cervical incision of goiter in mediastinum posterior and its indications].
  • OBJECTIVE: To explore the feasibility of cervical approach for goiter in posterior mediastinum.
  • METHOD: According to the mechanism that goiter filed into posterior mediastinum and the dissection of thyroid gland and mediastinum, we designed the following surgery principles (1) From top to bottom. (2) Find out recurrent nerve at the place where it enters larynx, then dissect recurrent nerve as long as possible and protect it carefully, meanwhile, search thyroid vessels along recurrent nerve. (3) To avoid and uncontrollable serious hemorrhage in the operation, all normal and aberrant blood vessels must be ligated cautiously, and avoid pulling great vessels in the thoracic part. (4) Separating tumor of hemorrhage under surgical capsule.
  • Bluntly, it can avoid damage important structure in most occasions. (5) If the tumor of hemorrhage was difficult to be separated from the surrounding structure, ask thoracic surgeon for cooperation.
  • CONCLUSION: Cervical approach for goiter in mediastinum posterior is an ideal method of surgery, but it has following operative indication. (1) imaging date indicate that tumor of posterior septum is not connected to the surrounding structure. (2) It is not accompanied with superior vena cava syndrome. (3) The size of large thyroid tumor of posterior septum could be decreased by taking out the center part of tumor, and it is suitable for liquidized center tissue especially, then take out the tumor from neck.
  • [MeSH-major] Goiter / surgery. Neck / surgery. Orthopedic Procedures / contraindications. Orthopedic Procedures / methods. Thyroid Neoplasms / surgery
  • [MeSH-minor] Female. Humans. Mediastinum / surgery. Middle Aged

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  • (PMID = 19166024.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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96. Moran CA: Primary neuroendocrine carcinomas of the mediastinum: review of current criteria for histopathologic diagnosis and classification. Semin Diagn Pathol; 2005 Aug;22(3):223-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary neuroendocrine carcinomas of the mediastinum: review of current criteria for histopathologic diagnosis and classification.
  • Primary neuroendocrine neoplasms occurring in the mediastinum are rare.
  • The spectrum of such tumors can range from low- to high-grade neoplasms.
  • The histogenesis of these tumors is varied, and some of them may originate from ectopic tissues in the mediastinum whereas others represent tumors native to the thymus.
  • Primary thymic neuroendocrine carcinomas therefore need to be separated from other neuroendocrine neoplasms of the mediastinum, namely ectopic parathyroid tumors and paragangliomas.
  • The histopathologic classification of primary neuroendocrine carcinomas of the mediastinum is still under debate and continues to be controversial, as is attested to by the different publications on the topic.
  • However, one aspect that all agree on is that, when they occur in the thymic region, these tumors should be considered as aggressive neoplasms capable of local recurrence and distant metastasis.
  • [MeSH-major] Carcinoma, Neuroendocrine / classification. Carcinoma, Neuroendocrine / diagnosis. Mediastinal Neoplasms / classification. Mediastinal Neoplasms / diagnosis. Thymus Neoplasms / classification. Thymus Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Prognosis

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  • (PMID = 16711403.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 78
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97. Puri V, Meyers BF: Utility of positron emission tomography in the mediastinum: moving beyond lung and esophageal cancer staging. Thorac Surg Clin; 2009 Feb;19(1):7-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of positron emission tomography in the mediastinum: moving beyond lung and esophageal cancer staging.
  • In the mediastinum, PET can provide information to distinguish thymic hyperplasia from neoplasia, although the use of this imaging for this purpose is not accepted uniformly as necessary.
  • PET is the standard of care in staging and follow-up of mediastinal lymphoma and in follow-up of metastatic seminomas after chemotherapy.
  • Mycobacterial/fungal infections, sarcoidosis, and brown fat can mimic malignant findings on PET in the mediastinum.
  • [MeSH-major] Mediastinum / radionuclide imaging. Positron-Emission Tomography. Thoracic Neoplasms / radionuclide imaging
  • [MeSH-minor] Fluorodeoxyglucose F18. Humans. Lymphoma / pathology. Lymphoma / radionuclide imaging. Neoplasm Staging. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals

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  • (PMID = 19288816.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 34
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98. Hung JJ, Lin SC, Hsu WH: Pancoast syndrome caused by metastasis to the superior mediastinum of hepatocellular carcinoma. Thorac Cardiovasc Surg; 2007 Oct;55(7):463-5
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancoast syndrome caused by metastasis to the superior mediastinum of hepatocellular carcinoma.
  • We present here a case of a 46-year-old man with an unusual metastasis to the superior mediastinum causing Pancoast syndrome eight months after a right hepatic lobectomy for HBV-related HCC.
  • [MeSH-major] Carcinoma, Hepatocellular / complications. Hepatitis B / complications. Liver Neoplasms / pathology. Mediastinal Neoplasms / complications. Pancoast Syndrome / etiology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Catheter Ablation. Fatal Outcome. Hepatectomy. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Thoracotomy. Tomography, X-Ray Computed

  • MedlinePlus Health Information. consumer health - Hepatitis B.
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  • (PMID = 17902073.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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99. Tanaka O, Kiryu T, Hirose Y, Iwata H, Hoshi H: Neurogenic tumors of the mediastinum and chest wall: MR imaging appearance. J Thorac Imaging; 2005 Nov;20(4):316-20
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurogenic tumors of the mediastinum and chest wall: MR imaging appearance.
  • Various histologic types of neurogenic tumors may originate in the mediastinum and chest wall.
  • It is possible to make accurate diagnosis of these tumors by using the multiplanar capability and high contrast resolution of MR imaging because of these characteristic imaging findings.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Mediastinal Neoplasms / diagnosis. Mediastinum / pathology. Neoplasms, Nerve Tissue / diagnosis. Thoracic Wall / pathology
  • [MeSH-minor] Diagnosis, Differential. Ganglioneuroma. Humans

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  • (PMID = 16282916.001).
  • [ISSN] 0883-5993
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 5
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100. González-Cruz A, García-Ferrer L, García C: [Cervical and mediastinum haematoma secondary to spontaneous thyroid rupture]. Acta Otorrinolaringol Esp; 2010 Nov-Dec;61(6):459-61
MedlinePlus Health Information. consumer health - Bleeding.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cervical and mediastinum haematoma secondary to spontaneous thyroid rupture].
  • [Transliterated title] Hematoma cervical y mediastínico secundario a rotura espontánea de tiroides.
  • We present a case of spontaneous haemorrhage of a thyroid nodule with diffusion of the haematoma to cervical spaces and mediastinum, which began as a progressive cervical mass affecting the airway and which required surgical treatment for control.
  • The diagnosis was made using ultrasonography and cervicothoracic CT scan, giving high quality images to determine the site of bleeding as well as the extent of the process.
  • [MeSH-minor] Aged. Female. Humans. Mediastinum. Neck. Rupture, Spontaneous

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  • [Copyright] Copyright © 2009 Elsevier España, S.L. All rights reserved.
  • [CommentIn] Acta Otorrinolaringol Esp. 2011 Mar-Apr;62(2):171 [21334581.001]
  • (PMID = 20152954.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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