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1. Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL: Protein biomarker identification in the CSF of patients with CNS lymphoma. J Clin Oncol; 2008 Jan 1;26(1):96-105
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Protein biomarker identification in the CSF of patients with CNS lymphoma.
  • We tested the hypothesis that individual CSF proteins distinguish CNS lymphoma from benign focal brain lesions.
  • METHODS: We used a liquid chromatography/mass spectrometry-based method to differentially quantify and identify several hundred CSF proteins in CNS lymphoma and control patients.
  • We propose that the discovery of CSF protein biomarkers will facilitate early and noninvasive diagnosis in patients with lesions not amenable to brain biopsy, as well as provide improved surrogates of prognosis and treatment response in CNS lymphoma and brain metastasis.
  • [MeSH-major] Biomarkers, Tumor / cerebrospinal fluid. Brain Neoplasms / cerebrospinal fluid. Lymphoma / cerebrospinal fluid. Neoplasm Proteins / cerebrospinal fluid
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antithrombin III / genetics. Antithrombin III / metabolism. Case-Control Studies. Chromatography, Liquid. Diagnosis, Differential. Enzyme-Linked Immunosorbent Assay. Female. Humans. Immunoblotting. Immunoenzyme Techniques. Leukemia, Myeloid / cerebrospinal fluid. Leukemia, Myeloid / pathology. Lymphoma, B-Cell / cerebrospinal fluid. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell, Marginal Zone / cerebrospinal fluid. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, Large B-Cell, Diffuse / cerebrospinal fluid. Lymphoma, Large B-Cell, Diffuse / pathology. Lymphoma, Non-Hodgkin / cerebrospinal fluid. Lymphoma, Non-Hodgkin / pathology. Male. Middle Aged. Proteomics. Sensitivity and Specificity. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization. Survival Rate

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  • [Cites] J Clin Oncol. 1999 Feb;17(2):554-60 [10080599.001]
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  • [CommentIn] J Clin Oncol. 2009 May 1;27(13):2302-3; author reply 2303-4 [19332721.001]
  • (PMID = 18056677.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / K23 CA100291
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 9000-94-6 / Antithrombin III
  • [Other-IDs] NLM/ NIHMS612770; NLM/ PMC4134101
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2. Jana AK, Jaswal A, Sikder B, Jana U, Nandi TK: Preauricular malignant lymphoma masqurading as benign pleomorphic adenoma - A rare tricky presentation. Indian J Otolaryngol Head Neck Surg; 2007 Dec;59(4):386-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preauricular malignant lymphoma masqurading as benign pleomorphic adenoma - A rare tricky presentation.
  • Lymphoma in the head neck area most commonly present as cervical lymph node swelling followed by tonsillar enlargement but the presentation as sole preauricular swelling without systemic involvement is a very rare finding.
  • Here we present a case of malignant lymphoma Grade I, presenting as a single prauricular swelling masquerading as a benign pleomorphic adenoma, in a 24 year old girl.

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  • (PMID = 23120483.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3452266
  • [Keywords] NOTNLM ; Malignant lymphoma / Pleomorphic adenoma / Preauricular region
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3. Omoti AE, Omoti CE: Ophthalmic manifestations of lymphoma. Ann Afr Med; 2007 Sep;6(3):89-93
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  • [Title] Ophthalmic manifestations of lymphoma.
  • BACKGROUND: Ophthalmic involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an intraocular manifestation of systemic lymphoma.
  • This report reviews the ophthalmic manifestations of lymphoma.
  • RESULTS: Almost all the structures in the orbit, adnexiae and eye can be involved in lymphoma.
  • Lymphoma of the eye and adnexiae are most frequently of B lineage.
  • Most of the ocular manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis, uveitis, multiple evanescent white dot syndrome, acute retinal necrosis or herpetic retinitis.
  • CONCLUSIONS: It is important to review the ocular manifestations of lymphoma to assist the ophthalmologist to play a pivotal role in the prompt diagnosis and treatment of ocular lymphoma, and the haematologist/oncologist to recognize the need for a complete ophthalmic evaluation in the diagnosis, follow-up and management of lymphoma patients.
  • [MeSH-major] Eye Diseases / etiology. Lymphoma / complications

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  • (PMID = 18240494.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Nigeria
  • [Number-of-references] 36
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4. Primrose WJ, Napier SS, Primrose AJ: Kikuchi-Fugimoto disease (Cervical Subacute Necrotising Lymphadenitis): an important benign disease often masquerading as lymphoma. Ulster Med J; 2009 May;78(2):134-6
HIV InSite. treatment guidelines - Ophthalmic Manifestations of HIV .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kikuchi-Fugimoto disease (Cervical Subacute Necrotising Lymphadenitis): an important benign disease often masquerading as lymphoma.
  • OBJECTIVES: We describe a rare cause of posterior triangle cervical lymphadenopathy in a third decade female, outline the clinical and histopathological features and discuss excision biopsy as the investigation of choice in this age group, with lymphoma as the diagnosis of exclusion.
  • She was "Red Flagged" as a possible lymphoma.
  • CONCLUSIONS: Persistent posterior triangle lymphadenopathy in the 16-40 year old age group warrants "Red Flag" referral to rule out serious pathology such as HIV, metastatic cancer or lymphoma.
  • [MeSH-minor] Adult. Female. Humans. Lymphoma / diagnosis. Lymphoma / pathology. Lymphoma / surgery

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  • [Cites] Am J Pathol. 1982 Jun;107(3):292-9 [6282130.001]
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  • (PMID = 19568451.001).
  • [ISSN] 0041-6193
  • [Journal-full-title] The Ulster medical journal
  • [ISO-abbreviation] Ulster Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Northern Ireland
  • [Other-IDs] NLM/ PMC2699202
  • [Keywords] NOTNLM ; Excision biopsy / Kikuchi-Fujimoto disease / Red Flag referral / cervical lymphadenopathy
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5. Ellis GL: Lymphoid lesions of salivary glands: malignant and benign. Med Oral Patol Oral Cir Bucal; 2007 Dec;12(7):E479-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoid lesions of salivary glands: malignant and benign.
  • Lesions of salivary glands with a prominent lymphoid component are a heterogeneous group of diseases that include benign reactive lesions and malignant neoplasms.
  • Lymphoepithelial sialadenitis, HIV-associated salivary gland disease, chronic sclerosing sialadenitis, Warthin tumor, and extranodal marginal zone B-cell lymphoma are examples of this pathology that are sometimes problematic to differentiate from one another.
  • [MeSH-minor] Adenolymphoma / diagnosis. Carcinoma / diagnosis. Humans. Lymphoma, B-Cell, Marginal Zone / diagnosis. Prognosis. Sialadenitis / diagnosis

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  • (PMID = 17978770.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 30
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6. Sata N, Kurogochi A, Endo K, Shimura K, Koizumi M, Nagai H: Follicular lymphoma of the pancreas: a case report and proposed new strategies for diagnosis and surgery of benign or low-grade malignant lesions of the head of the pancreas. JOP; 2007;8(1):44-9
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  • [Title] Follicular lymphoma of the pancreas: a case report and proposed new strategies for diagnosis and surgery of benign or low-grade malignant lesions of the head of the pancreas.
  • CONTEXT: Primary pancreatic lymphoma is a rare form of extranodal lymphoma originating in the pancreas.
  • The present report describes a case of follicular lymphoma of the pancreas with unique CT and MRI findings.
  • Follicular lymphoma is quite rare in the pancreas and gastrointestinal tract.
  • A considerable number of pancreatic lymphoma subtypes have been reported.
  • The expression "pancreatic lymphoma" has been used to describe both primary lymphoid neoplasms originating in the pancreatic parenchyma and tumors invading from a peri-pancreatic lymphadenopathy.
  • In the future, primary pancreatic lymphoma should be discussed separately depending on the subtype.
  • CONCLUSION: We propose a new subtype of primary pancreatic lymphoma.
  • Enucleation is indicated for benign and low-grade malignant tumors of the pancreas, even if the tumor is located in the head of the pancreas.
  • [MeSH-major] Lymphoma, Follicular / diagnosis. Pancreas / pathology. Pancreatic Neoplasms / diagnosis

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  • (PMID = 17228133.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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7. Arshad AR: Benign parotid lesions: is near total parotidectomy justified? Ann Acad Med Singapore; 2006 Dec;35(12):889-91

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign parotid lesions: is near total parotidectomy justified?
  • INTRODUCTION: Benign tumours of the parotid gland constitute about 80% of parotid tumours.
  • The most common benign tumour of the parotid gland is pleomorphic adenoma.
  • Various modes of treatment have been advocated for the treatment of benign parotid lesions, ranging from enucleation to near-total parotidectomy.
  • MATERIAL AND METHODS: This is an audit of an 18-year period where 173 lesions of the parotid gland (34 malignant and 139 benign lesions) were treated by the author.
  • RESULTS: There were 139 benign lesions, of which 123 were benign tumours and 16 non-tumour conditions.
  • Near-total parotidectomy was performed on all these cases with benign lesions.
  • Near-total parotidectomy should be considered when there is a need to treat benign parotid swellings.
  • [MeSH-minor] Adenoma, Pleomorphic / surgery. Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Lymphoma / surgery. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17219001.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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8. Morales AV, Arber DA, Seo K, Kohler S, Kim YH, Sundram UN: Evaluation of B-cell clonality using the BIOMED-2 PCR method effectively distinguishes cutaneous B-cell lymphoma from benign lymphoid infiltrates. Am J Dermatopathol; 2008 Oct;30(5):425-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of B-cell clonality using the BIOMED-2 PCR method effectively distinguishes cutaneous B-cell lymphoma from benign lymphoid infiltrates.
  • We hypothesized that clonality detection in CBCL with the BIOMED-2 method could effectively distinguish malignant from benign B-cell-rich infiltrates in the skin.
  • Formalin-fixed tissue samples from 26 patients with CBCL and 23 with benign lymphoid infiltrates were analyzed for Ig clonality using standardized BIOMED-2 polymerase chain reaction protocols.
  • A clone was detected in 22 (85%) of the 26 patients with CBCL [12/15 (80%) marginal zone B-cell lymphoma; 10/11 (91%) follicle center lymphoma] and in 1 (4%) of the 23 patients with benign infiltrates.
  • The (14;18) translocation was present in 3 (12%) of the 26 patients with CBCL [1/15 (7%) marginal zone B-cell lymphoma; 2/11 (18%) follicle center lymphoma].
  • This study forms the basis for further investigating the role of Ig clonality in distinguishing CBCL from benign lymphoid infiltrates that may pose a challenge in morphologic diagnosis.
  • [MeSH-major] B-Lymphocytes / pathology. Lymphoma, B-Cell / diagnosis. Polymerase Chain Reaction / methods. Skin Diseases / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18806482.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin Heavy Chains; 0 / Immunoglobulin kappa-Chains
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9. Rodríguez-Vázquez M, García-Arpa M, Martín F, Calle C, Marchán E, Romero G, Cortina P: [Panniculitic T-cell lymphoma]. Actas Dermosifiliogr; 2005 Mar;96(2):98-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Panniculitic T-cell lymphoma].
  • [Transliterated title] Linfoma de células T paniculítico.
  • Panniculitic T-cell lymphoma is a rare, aggressive variant of cutaneous T-cell lymphoma, with fewer than 100 cases described.
  • The main problem is its diagnosis, as both the clinical and the histological features may simulate benign panniculitis.
  • After two skin biopsies, the patient was diagnosed with panniculitic cutaneous T-cell lymphoma.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476344.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 28
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10. Zhang MD, Zhao YN, An LW: [B-cell lymphoma/leukemia-2 and benign prostatic hyperplasia]. Zhonghua Nan Ke Xue; 2009 May;15(5):452-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [B-cell lymphoma/leukemia-2 and benign prostatic hyperplasia].
  • The B-cell lymphoma/leukemia-2 (Bcl-2) gene is an important member of the Bcl-2 family, a type of protein that plays an important role in the process of cell apoptosis.
  • In the recent years, more and more evidence has shown a close correlation of the Bcl-2 gene with the development and progression of benign prostatic hyperplasia (BPH), a disease whose mechanism is not yet fully understood but is drawing more and more attention towards the role of cell apoptosis.

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  • (PMID = 19514561.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-bcl-2
  • [Number-of-references] 18
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11. Gill MT, Cotelingam JD, Lowery-Nordberg M, Nathan CO: Tracheal non-Hodgkin's lymphoma masquerading as benign granulation tissue: a report of two cases. Ann Otol Rhinol Laryngol; 2010 Jul;119(7):431-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tracheal non-Hodgkin's lymphoma masquerading as benign granulation tissue: a report of two cases.
  • Primary tracheal non-Hodgkin's lymphoma (NHL) is rare, with fewer than 30 cases reported to date.
  • In both cases, bronchoscopy revealed abundant granulation tissue, and the initial biopsy results indicated benign disease.
  • However, after requests from the diagnostic team to rule out lymphoma, additional immunohistochemical stains and polymerase chain reaction testing confirmed NHL.
  • Recurrent granulation tissue should raise the suspicion of malignancy and prompt further tissue evaluation for evidence of lymphoma.
  • Steroids for airway compromise may cause progression to mature stenosis as prednisone is used in the treatment of lymphoma.
  • [MeSH-major] Granulation Tissue / pathology. Lymphoma, Non-Hodgkin / diagnosis. Tracheal Neoplasms / diagnosis

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  • (PMID = 20734962.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Zhang D, O'neil MF, Cunningham MT, Fan F, Olyaee M, Li L: Abnormal Wnt signaling and stem cell activation in reactive lymphoid tissue and low-grade marginal zone lymphoma. Leuk Lymphoma; 2010 May;51(5):906-10
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  • [Title] Abnormal Wnt signaling and stem cell activation in reactive lymphoid tissue and low-grade marginal zone lymphoma.
  • The variable natural history of mucosa-associated lymphoid tissue (MALT) lymphoma poses a challenge in predicting clinical outcome.
  • Since Wnt signaling, as indicated by nuclear localization of beta-catenin, is believed to be key in stem cell activation and stem cell self-renewal, we explored the possibility that it might have a predictive value in marginal zone lymphoma.
  • Wnt signaling and activation was studied in 22 tissue samples of extranodal marginal zone lymphoma, atypical lymphoid hyperplasia, reactive lymphoid hyperplasia, and normal lymphoid tissue to determine whether Wnt signaling could help distinguish MALT lymphoma from benign lesions.
  • Compared to normal or reactive lymphoid tissue, we found increased nuclear expression of localized pbeta-catenin-S552 in atypical lymphoid hyperplasia and extranodal marginal zone lymphoma.
  • We show that the anti-pbeta-catenin-S552 antibody may be useful in diagnosing and monitoring the progression of or response to therapy of MALT lymphoma.
  • [MeSH-major] Lymphoid Tissue / metabolism. Lymphoma, B-Cell, Marginal Zone / metabolism. Lymphoma, Non-Hodgkin / metabolism. Pseudolymphoma / metabolism. Stem Cells / metabolism. beta Catenin / metabolism

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  • (PMID = 20233054.001).
  • [ISSN] 1029-2403
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / beta Catenin
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13. Greco L, Marino F, Troilo VL, Marzullo A, Gentile A: Gastric stump lymphoma after distal gastrectomy for benign peptic ulcer: Report of a case. Surg Today; 2006;36(11):985-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric stump lymphoma after distal gastrectomy for benign peptic ulcer: Report of a case.
  • We report a case of primary non-Hodgkin gastric stump lymphoma, found in a 78-year-old man 30 years after a distal gastrectomy for a benign peptic ulcer.
  • The development of lymphoma in the gastric stump is rare.
  • Conversely, bile reflux and nitrite and N-nitrous compounds caused by abnormal bacterial growth in the gastric stump may play a role in inducing mucosa-associated lymphoid tissue lymphoma.
  • [MeSH-major] Gastrectomy / adverse effects. Gastric Stump. Lymphoma, B-Cell / etiology. Stomach Neoplasms / etiology. Stomach Ulcer / surgery

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  • (PMID = 17072720.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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14. Gundrum JD, Go R, Kwong R: Cancer in the oldest old population in the United States: Current statistics and projections. J Clin Oncol; 2009 May 20;27(15_suppl):9553

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We included patients who had a previous cancer before age 85, but excluded benign tumors, myeloproliferative, and myelodysplastic neoplasms.
  • The 10 leading cancers by incidence (both sexes and decreasing order) are colorectal (388.9), lung (287.7), breast (250), prostate (211.5), urinary bladder (162.5), non-Hodgkin lymphoma (110.9), leukemia (85.1), melanoma (65), renal (46.4), and uterine (40.2).
  • The incidences of melanoma, non-Hodgkin lymphoma, renal, and lung cancers are increasing, while those of leukemia, prostate, breast, and colorectal cancers are decreasing.
  • Cancer specific survival (CSS) has been increasing continuously since 1973 for melanoma, non-Hodgkin lymphoma, breast, colorectal, prostate, and urinary bladder cancers but decreasing in recent years for colorectal, breast, prostate, and uterine cancers.

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  • (PMID = 27963637.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Yi J, Kim S, Lee S, Park S, Ko Y, Choi J, Kim W: Clinical usefulness of PET/CT in initial staging and response evaluation of primary gastric lymphoma. J Clin Oncol; 2009 May 20;27(15_suppl):e19541

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical usefulness of PET/CT in initial staging and response evaluation of primary gastric lymphoma.
  • : e19541 Background: Positron emission tomography (PET)/computed tomography (CT) scan has a well-established role in the management of non-Hodgkin's lymphoma (NHL).
  • However, in case of the primary gastric lymphoma, which is the most frequent extranodal NHL, the role of PET/CT scan is still controversial.
  • METHODS: We retrospectively analyzed 42 patients with primary gastric lymphoma who underwent PET/CT scans; 32 patients with diffuse large B-cell lymphoma (DLBCL) and 10 patients with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) were analyzed.
  • All of these gastric lesions were grossly and pathologically benign lesions without evidence of lymphoma cells.
  • CONCLUSIONS: PET/CT scan can help staging patients with primary gastric lymphoma, and the maximum SUV has possibility to have prognostic value.

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  • (PMID = 27960998.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Matsumoto K, Sawaki A, Kobayashi Y, Mizuno N, Hara K, Takagi T, Sawai Y, Shimizu Y, Yatabe Y, Yamao K: Diagnostic yield of nonfunctional pancreatic neuroendocrine tumor using endoscopic ultrasound-guided fine needle aspiration biopsy. J Clin Oncol; 2009 May 20;27(15_suppl):e15680

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diagnosis by CT and EUS was 12 (75.0%) PNETs, two pancreatic cancer, one solid papillary tumors and one malignant lymphoma.
  • The Ki-67 in specimens of malignancy tended to be higher than those of benign or uncertain behavior.

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  • (PMID = 27962818.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Rofail M, Lee LR, Whitehead K: Conjunctival benign reactive lymphoid hyperplasia associated with myopic scleral thinning. Clin Exp Ophthalmol; 2005 Feb;33(1):73-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival benign reactive lymphoid hyperplasia associated with myopic scleral thinning.
  • Known causes of conjunctival salmon patches include lymphoma, amyloidosis, sarcoidosis, leukaemia and benign reactive lymphoid hyperplasia.
  • The aetiology of benign reactive lymphoid hyperplasia is thought to be a localized reactive change induced by an irritative or antigenic stimulus.
  • The case of benign reactive lymphoid hyperplasia reported herein occurred in a myopic patient with extremely thin sclera.

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  • (PMID = 15670084.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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18. Hossain FS, Koak Y, Khan FH: Primary gastric Hodgkin's lymphoma. World J Surg Oncol; 2007;5:119
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary gastric Hodgkin's lymphoma.
  • Nearly all cases of primary gastric lymphoma are of the non-Hodgkin's variety.
  • Subsequent multiple upper GI endoscopies revealed a large malignant looking ulcer which was deemed to be histologically benign.
  • CONCLUSION: Our case illustrates the significant difficulties in achieving a rare diagnosis of primary Hodgkin's lymphoma of the stomach.

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  • (PMID = 17949508.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2117016
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19. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T: [Incidence of benign and malignant lesions of eyelid and conjunctival tumors]. Nippon Ganka Gakkai Zasshi; 2005 Sep;109(9):573-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Incidence of benign and malignant lesions of eyelid and conjunctival tumors].
  • PURPOSE: To examine the incidence of benign and malignant eyelid lesions and conjunctival tumors.
  • The incidence of benign or malignant lesions, the pathological classification, age, sex, and clinical diagnostic accuracy were all investigated.
  • RESULTS: Sixty-four (73%) of the tumors were found to be benign eyelid tumors.
  • The common benign eyelid tumors were 14 nevocellular nevi, 9 seborrheic keratosis, 7 epidermoid cysts, and 6 papillomas.
  • Thirty-four (79%) conjunctival tumors were benign, and the common benign conjunctival tumors were 9 nevocellular nevi and 7 papillomas.
  • The mean ages of malignant eyelid and conjunctival tumor patients were significantly older than those of benign tumor patients.
  • CONCLUSIONS: Approximately 70 approximately 80% of all eyelid and conjunctival tumors are benign.
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Female. Humans. Incidence. Lymphoma / epidemiology. Lymphoma / pathology. Male. Middle Aged. Retrospective Studies

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  • (PMID = 16218435.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 27
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20. Abdelwahab IF, Hoch B, Hermann G, Bianchi S, Klein MJ, Springfield DS: Primary periosteal lymphoma--rare and unusual. Skeletal Radiol; 2007 Apr;36(4):335-9
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary periosteal lymphoma--rare and unusual.
  • We describe a primary periosteal lymphoma that involved only the periosteum without affecting the adjacent medulla or the regional lymph nodes.
  • This unusual presentation simulates the imaging appearance of surface lesions of bone, namely benign and malignant tumors, and departs from the typical appearance of primary lymphoma of bone.
  • Therefore, this rare type of lymphoma should be considered in the differential diagnosis of surface bone lesions.
  • [MeSH-major] Bone Neoplasms / diagnosis. Femur / pathology. Lymphoma, Large B-Cell, Diffuse / diagnosis. Periosteum / pathology

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  • (PMID = 16534637.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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21. van Gelder M, Bot FJ: [Kikuchi's histiocytic necrotising lymphadenitis: a benign disorder--not to be confused with malignant lymphoma]. Ned Tijdschr Geneeskd; 2006 Sep 23;150(38):2099-103
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Kikuchi's histiocytic necrotising lymphadenitis: a benign disorder--not to be confused with malignant lymphoma].
  • [Transliterated title] Histiocytaire necrotiserende lymfadenitis van Kikuchi: een benigne aandoening--niet te verwarren met maligne lymfoom.
  • A 26-year-old woman who later turned out to have the rarely seen histiocytic necrotising lymphadenitis of Kikuchi was twice diagnosed incorrectly with malignant T-cell lymphoma.
  • Fear for recurrent lymphoma greatly affected the patient's life until the proper diagnosis was ultimately made.
  • This occurred after the patient herself had seen in her dossier that the diagnosis 'Kikuchi's histiocytic lymphadenitis' had been proposed by two pathologists of the consulted regional lymphoma board in the past, but had been rejected by the board after external consultation.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Lymphoma, T-Cell / diagnosis. Necrosis

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  • (PMID = 17036863.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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22. Levy AD, Rimola J, Mehrotra AK, Sobin LH: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics; 2006 Jan-Feb;26(1):245-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation.
  • Mesenteric fibromatosis, sclerosing mesenteritis, inflammatory pseudotumor, and extrapleural solitary fibrous tumor constitute a loosely associated group of benign fibrous tumors and tumorlike lesions of the mesentery.
  • Mesenteric fibromatosis is a locally aggressive, benign proliferative process that may occur sporadically or in association with familial adenomatous polyposis.
  • It most frequently manifests as a focal mesenteric mass and may simulate lymphoma, metastatic disease, or a soft-tissue sarcoma.
  • Inflammatory pseudotumor (inflammatory myofibroblastic tumor) is a benign, chronic inflammatory disorder of unknown cause that manifests as a solid mesenteric mass, indistinguishable from malignancy.
  • When located in the mesentery or peritoneal cavity, extrapleural solitary fibrous tumor has an imaging pattern that must be differentiated from metastatic disease, soft-tissue sarcomas, and other benign and malignant neoplasms of the mesentery and peritoneum.
  • Knowledge of this group of benign fibrous tumors and tumorlike lesions of the mesentery is important in the preoperative evaluation of a mesenteric mass.

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  • (PMID = 16418255.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 57
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23. Romaguera J, Hagemeister FB: Lymphoma of the colon. Curr Opin Gastroenterol; 2005 Jan;21(1):80-4
MedlinePlus Health Information. consumer health - Hodgkin Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoma of the colon.
  • PURPOSE OF REVIEW: This review updates the status of the diagnosis of colonic lymphoma, whether primary or as part of a generalized presentation.
  • RECENT FINDINGS: Mantle cell lymphoma has a much higher incidence of colonic presentation than previously reported, presents mostly in asymptomatic patients, and is detected microscopically in 50% of patients after a biopsy of a visually benign mucosa.
  • There are reports suggesting a receptor-driven homing mechanism in lymphoma genesis for both of these entities.
  • Patients with a history of chronic inflammatory bowel disease should have their biopsy specimens subjected to rigorous analysis including immunophenotypic and genotypic studies to rule out underlying lymphoma.
  • [MeSH-major] Colonic Neoplasms / pathology. Hodgkin Disease / pathology. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, Mantle-Cell / pathology. Lymphoma, T-Cell, Peripheral / pathology

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  • (PMID = 15687889.001).
  • [ISSN] 0267-1379
  • [Journal-full-title] Current opinion in gastroenterology
  • [ISO-abbreviation] Curr. Opin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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24. Moghazy KM: Gastrosplenic fistula following chemotherapy for lymphoma. Gulf J Oncolog; 2008 Jan;(3):64-7
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  • [Title] Gastrosplenic fistula following chemotherapy for lymphoma.
  • Gastrosplenic fistula resulting from erosion of a primary splenic lymphoma is a very rare cause of massive upper gastrointestinal hemorrhage as compared to benign peptic ulcer disease, gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas.
  • A 50-year-old patient developed a gastrosplenic fistula during a course of chemotherapy for differentiated histiocytic lymphoma.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Gastric Fistula / chemically induced. Lymphoma, Large B-Cell, Diffuse / drug therapy. Splenic Diseases / chemically induced

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  • (PMID = 20084800.001).
  • [ISSN] 2078-2101
  • [Journal-full-title] The Gulf journal of oncology
  • [ISO-abbreviation] Gulf J Oncolog
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Kuwait
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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25. Heidebrecht HJ, Claviez A, Kruse ML, Pollmann M, Buck F, Harder S, Tiemann M, Dörffel W, Parwaresch R: Characterization and expression of CT45 in Hodgkin's lymphoma. Clin Cancer Res; 2006 Aug 15;12(16):4804-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization and expression of CT45 in Hodgkin's lymphoma.
  • PURPOSE: The monoclonal antibody Ki-A10 (IgG1) generated after immunization of mice with Hodgkin's lymphoma cell line L428 detects a nuclear antigen in human tissues with a restricted distribution pattern similar to cancer/testis antigens.
  • The aim of this study was to characterize the antigen and to determine the expression profile in Hodgkin's lymphoma.
  • In comparison, 54 of 99 (55%) samples from pediatric and adolescent Hodgkin's lymphoma patients enrolled in the multicenter trial HD-95 stained Ki-A10 positive.
  • Ki-A10 expression correlated with histologic subtypes (nodular sclerosis Hodgkin's lymphoma 68% versus mixed cellularity Hodgkin's lymphoma 40% versus nodular lymphocyte predominant Hodgkin's lymphoma 9%; P < 0.001).
  • As benign lymphoid lesions did not express CT45, the use of Ki-A10 antibody will facilitate the discrimination of Hodgkin's lymphoma from reactive lymphadenopathies.
  • [MeSH-minor] Adolescent. Antibodies, Monoclonal / immunology. Child. Child, Preschool. Female. HeLa Cells. Humans. Lymphoma / immunology. Lymphoma / metabolism. Male. Molecular Sequence Data. Protein Processing, Post-Translational

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  • (PMID = 16914565.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Neoplasm; 0 / CT45A1 protein, human
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26. Ponti R, Quaglino P, Novelli M, Fierro MT, Comessatti A, Peroni A, Bonello L, Bernengo MG: T-cell receptor gamma gene rearrangement by multiplex polymerase chain reaction/heteroduplex analysis in patients with cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome) and benign inflammatory disease: correlation with clinical, histological and immunophenotypical findings. Br J Dermatol; 2005 Sep;153(3):565-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] T-cell receptor gamma gene rearrangement by multiplex polymerase chain reaction/heteroduplex analysis in patients with cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome) and benign inflammatory disease: correlation with clinical, histological and immunophenotypical findings.
  • BACKGROUND: A dominant T-cell clone can be detected by polymerase chain reaction (PCR) in 40-90% of cutaneous samples from patients with cutaneous T-cell lymphoma (CTCL).
  • The final diagnosis was benign inflammatory disease (BID) in 353 samples (64.5%) and CTCL in 194 (35.5%).


27. Baker R, Slayden G, Jennings W: Multifocal primary breast lymphoma. South Med J; 2005 Oct;98(10):1045-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multifocal primary breast lymphoma.
  • Primary breast lymphoma (PBL) is a rare condition, accounting for only 0.04 to 0.5% of breast malignancies and less than 2% of extranodal lymphomas.
  • Clinical presentation and imaging may suggest a benign condition.
  • [MeSH-major] Breast Neoplasms / pathology. Lymphoma / pathology
  • [MeSH-minor] Antigens, CD20 / analysis. Fatal Outcome. Female. Humans. Immunohistochemistry. Lymphoma, B-Cell / metabolism. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / therapy. Middle Aged. Ultrasonography, Mammary

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  • (PMID = 16295824.001).
  • [ISSN] 0038-4348
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD20
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28. Bergman R: Pseudolymphoma and cutaneous lymphoma: facts and controversies. Clin Dermatol; 2010 Sep-Oct;28(5):568-74
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pseudolymphoma and cutaneous lymphoma: facts and controversies.
  • Cutaneous pseudolymphoma refers to a heterogenous group of benign reactive T-cell or B-cell lymphoproliferative processes of diverse causes that simulate cutaneous lymphomas clinically and histologically.
  • Although this enables a more precise differentiation from cutaneous lymphoma, a substantial number of patients still present in whom the differential diagnosis is difficult or impossible.
  • Some evidence suggests that pseudolymphomas may progress to cutaneous lymphoma due to persistent antigenic stimulation.
  • More compelling evidence is needed, especially when most cutaneous pseudolymphoma are not associated with known antigens and the differentiation from cutaneous lymphoma may be difficult; therefore, a careful approach should be used, and the antigenic stimulus should be removed whenever possible.
  • [MeSH-major] Lymphoma, B-Cell / diagnosis. Lymphoma, T-Cell, Cutaneous / diagnosis. Pseudolymphoma / diagnosis. Skin Neoplasms / diagnosis

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20797521.001).
  • [ISSN] 1879-1131
  • [Journal-full-title] Clinics in dermatology
  • [ISO-abbreviation] Clin. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Mendenhall WM, Olivier KR, Lynch JW Jr, Mendenhall NP: Lethal midline granuloma-nasal natural killer/T-cell lymphoma. Am J Clin Oncol; 2006 Apr;29(2):202-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lethal midline granuloma-nasal natural killer/T-cell lymphoma.
  • PURPOSE: The purpose of this paper is to discuss lethal midline granuloma (LMG)-nasal natural killer (NK) T-cell lymphoma (LMG-NTL).
  • CONCLUSIONS: LMG-NTL is a rare nasal NK/T-cell lymphoma that can be difficult to distinguish from other benign and malignant entities.
  • [MeSH-major] Granuloma, Lethal Midline / pathology. Lymphoma, T-Cell / pathology. Nose Neoplasms / pathology

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  • (PMID = 16601443.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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30. Rosso R, Pretolesi F, del Bono V, Buscaglia M, Ferrando S, Farinella ST, di Biagio A, Bassetti M, Derchi LE, Viscoli C: Benign lymphoepithelial parotid lesions in vertically HIV-infected patients. AIDS Patient Care STDS; 2006 Aug;20(8):536-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign lymphoepithelial parotid lesions in vertically HIV-infected patients.
  • Benign lymphoepithelial parotid lesions (BLL) are frequently reported in HIV-infected patients, although their clinical and prognostic significance in HIV infection has not been clearly defined.
  • None of them had any symptoms ascribed to "sicca syndrome" and only one patient developed non-Hodgkin's lymphoma during the follow-up, although his USG pattern at baseline was type 0.

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  • (PMID = 16893322.001).
  • [ISSN] 1087-2914
  • [Journal-full-title] AIDS patient care and STDs
  • [ISO-abbreviation] AIDS Patient Care STDS
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Hurley MY, George MN, Leonardi CL, Frater JL: A transient benign lymph node-based proliferation of T-cells simulating non-Hodgkin lymphoma in a patient with psoriasis treated with tumor necrosis factor alpha and CD11a antagonists. Diagn Pathol; 2008;3:13

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A transient benign lymph node-based proliferation of T-cells simulating non-Hodgkin lymphoma in a patient with psoriasis treated with tumor necrosis factor alpha and CD11a antagonists.
  • BACKGROUND: Therapeutic biologic agents are uncommonly associated with lymphoma.
  • CASE PRESENTATION: We report a patient with psoriasis treated with the biologic agents efalizumab (Raptiva) and etanercept (Enbrel), who developed painless lymphadenopathy with peripheral lymphocytosis during treatment, simulating a non-Hodgkin lymphoma clinically and pathologically.
  • CONCLUSION: Distinction between clinically benign lymphoid proliferations related to anti-psoriasis therapy and malignant lymphoma avoids the unnecessary use of anti-lymphoma chemotherapy.

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  • [Cites] J Invest Dermatol. 2000 Mar;114(3):587-90 [10692122.001]
  • [Cites] Arch Dermatol. 2001 Jun;137(6):778-83 [11405770.001]
  • [Cites] Arthritis Rheum. 2002 Dec;46(12):3151-8 [12483718.001]
  • [Cites] Clin Lymphoma Myeloma. 2006 Jan;6(4):329-32 [16507211.001]
  • [Cites] J Dermatolog Treat. 2004 Sep;15(5):280-94 [15370396.001]
  • [Cites] J Am Acad Dermatol. 2004 Oct;51(4):660-2 [15389210.001]
  • [Cites] Arch Dermatol. 2004 Feb;140(2):218-25 [14967799.001]
  • (PMID = 18366773.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2291032
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32. Lam J, Pope E: Pediatric pityriasis lichenoides and cutaneous T-cell lymphoma. Curr Opin Pediatr; 2007 Aug;19(4):441-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric pityriasis lichenoides and cutaneous T-cell lymphoma.
  • PURPOSE OF REVIEW: The purpose of this review is to educate the reader about two cutaneous lymphoproliferative diseases in childhood: pityriasis lichenoides and cutaneous T-cell lymphoma.
  • The two forms of the disease, however, are best thought of as two ends of a benign lymphoproliferative spectrum.
  • Cutaneous T-cell lymphoma is a rare but underrecognized cutaneous malignancy in children.
  • Early stage disease and hypopigmented presentation are characteristic of pediatric cutaneous T-cell lymphoma.
  • RECENT FINDINGS: This article will summarize recent articles on pityriasis lichenoides and pediatric cutaneous T-cell lymphoma, including recent findings from an international registry of pediatric cutaneous T-cell lymphoma.
  • SUMMARY: After reading this review, the reader should be able to recognize the clinical presentation of pityriasis lichenoides, to understand the overlap between its acute and chronic forms, and to recognize its relationship with cutaneous T-cell lymphoma.
  • In addition, the reader will appreciate the challenges in diagnosing and treating pediatric cutaneous T-cell lymphoma.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / diagnosis. Pityriasis Lichenoides / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17630609.001).
  • [ISSN] 1040-8703
  • [Journal-full-title] Current opinion in pediatrics
  • [ISO-abbreviation] Curr. Opin. Pediatr.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 54
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33. von Herbay A, Barreiros AP, Ignee A, Westendorff J, Gregor M, Galle PR, Dietrich C: Contrast-enhanced ultrasonography with SonoVue: differentiation between benign and malignant lesions of the spleen. J Ultrasound Med; 2009 Apr;28(4):421-34
Hazardous Substances Data Bank. SULFUR HEXAFLUORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Contrast-enhanced ultrasonography with SonoVue: differentiation between benign and malignant lesions of the spleen.
  • OBJECTIVE: We investigated the ability of contrast-enhanced ultrasonography with SonoVue (Bracco SpA, Milan, Italy), a sulfur hexafluoride microbubble contrast agent, to reveal differences between benign and malignant focal splenic lesions.
  • RESULTS: In 14 patients, the splenic lesions were malignant (metastasis, n = 6; non-Hodgkin lymphoma, n = 6; and Hodgkin lymphoma, n = 2).
  • In 21 patients, the focal splenic lesions were benign (ischemic lesion, n = 6; echogenic cyst, n = 5; abscess, n = 4; hemangioma, n = 3; hematoma, n = 1; hemophagocytosis syndrome, n = 1; and splenoma, n = 1.
  • Typical findings for benign lesions were 2 arrival patterns: no contrast enhancement (neither in the early nor in the parenchymal phase; P < .05) and the beginning of contrast enhancement in the early phase followed by contrast enhancement in the parenchymal phase 60 seconds after injection.
  • CONCLUSIONS: Contrast-enhanced ultrasonography is helpful in the differentiation between benign and malignant lesions of the spleen.
  • [MeSH-major] Image Enhancement / methods. Lymphoma / ultrasonography. Phospholipids. Splenic Neoplasms / ultrasonography. Sulfur Hexafluoride

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  • (PMID = 19321670.001).
  • [ISSN] 1550-9613
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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34. Carnelio S, Rodrigues G: Benign lymphoid hyperplasia of the tongue masquerading as carcinoma: case report and literature review. J Contemp Dent Pract; 2005 Aug 15;6(3):111-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign lymphoid hyperplasia of the tongue masquerading as carcinoma: case report and literature review.
  • Lymphoid hyperplasia of the tongue is a very rare benign lymphoproliferative lesion that closely resembles carcinoma or lymphoma, clinically or histopathologically.
  • A case of benign lymphoid hyperplasia (BLH) of the tongue is reported.
  • Microscopy showed typical histologic features of multiple germinal centers with a rim of small mature lymphocytes together with a mixed, mainly mononuclear infiltrate which clinched the diagnosis of benign lymphoid hyperplasia.
  • Their distinction from carcinoma and lymphoma is discussed.
  • [MeSH-minor] Adult. Carcinoma / diagnosis. Diagnosis, Differential. Female. Humans. Hyperplasia. Immunohistochemistry. Lymphoma / diagnosis. Tongue Neoplasms / diagnosis

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  • (PMID = 16127479.001).
  • [ISSN] 1526-3711
  • [Journal-full-title] The journal of contemporary dental practice
  • [ISO-abbreviation] J Contemp Dent Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 11
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35. Kyrmizakis DE, Hajiioannou JK, Koutsopoulos AV, Papadaki E, Papadakis D, Bizakis J, Velegrakis G: Primary nasal non-Hodgkin lymphomas presented initially as benign disease. Am J Otolaryngol; 2006 May-Jun;27(3):217-20
Hazardous Substances Data Bank. VINCRISTINE .

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  • [Title] Primary nasal non-Hodgkin lymphomas presented initially as benign disease.
  • METHODS-RESULTS: We present three cases of NHLs, initially diagnosed as benign diseases.
  • CONCLUSION: It is important to underline that atypical or persistent symptoms of rhinosinusitis may represent the initial expression of a more serious condition such as deep fungal infection, vasculitis, lymphoma, or other malignancy.
  • [MeSH-major] Lymphoma, Non-Hodgkin / diagnosis. Nose Neoplasms / diagnosis

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  • (PMID = 16647990.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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36. Lee PS, Beneck D, Weisberger J, Gorczyca W: Coexpression of CD43 by benign B cells in the terminal ileum. Appl Immunohistochem Mol Morphol; 2005 Jun;13(2):138-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexpression of CD43 by benign B cells in the terminal ileum.
  • Expression of CD43 by B cells is often used as a diagnostic criterion in favor of a B-cell lymphoproliferative disorder, including small lymphocytic lymphoma/chronic lymphocytic leukemia, mantle cell lymphoma, Burkitt lymphoma, precursor B-lymphoblastic lymphoma, and a subset of marginal zone B-cell lymphomas.
  • Benign B cells generally do not coexpress CD43.
  • The majority of cases (85%) showed strong coexpression of CD43 by benign perifollicular B cells.
  • The presence of CD43 coexpression in B-cell populations of the terminal ileum, including those of Peyer's patches, should not be used as a diagnostic parameter to differentiate extranodal marginal zone B-cell lymphoma of MALT type from reactive processes.

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  • (PMID = 15894925.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD43; 0 / Sialoglycoproteins; 0 / UN1 sialoglycoprotein, human
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37. Abdussalam A, Gerridzen RG: Mantle cell lymphoma of the prostate. Can Urol Assoc J; 2009 Dec;3(6):E94-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mantle cell lymphoma of the prostate.
  • Lymphoma of the prostate, either primary or secondary, is very rare.
  • We report the case of an 82-year-old man with symptoms of bladder outlet obstruction presumably due to benign prostate hyperplasia (BPH).
  • Histology and immunoprofile were consistent with mantle cell lymphoma.

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  • [Cites] J Urol. 1985 Apr;133(4):615-6 [3981711.001]
  • [Cites] J Clin Oncol. 2003 Dec 1;21(23):4456-8 [14645437.001]
  • [Cites] Cancer. 1998 Aug 15;83(4):732-8 [9708938.001]
  • (PMID = 20019965.001).
  • [ISSN] 1920-1214
  • [Journal-full-title] Canadian Urological Association journal = Journal de l'Association des urologues du Canada
  • [ISO-abbreviation] Can Urol Assoc J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2792431
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38. Roy S, Dobson P, Henry L: An isolated osteochondroma with underlying non-Hodgkin's lymphoma of bone. J Bone Joint Surg Br; 2005 Oct;87(10):1423-4
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  • [Title] An isolated osteochondroma with underlying non-Hodgkin's lymphoma of bone.
  • Osteochondroma is the most common benign bone tumour.
  • We report a case of an isolated osteochondroma which appeared benign on clinical and plain radiographic examination but routine histological analysis revealed non-Hodgkin's lymphoma in the underlying bone.
  • This association has not previously been reported and the case emphasises the importance of routine histological analysis, even if a lesion appears benign.
  • [MeSH-major] Bone Neoplasms / pathology. Lymphoma, Large B-Cell, Diffuse / pathology. Neoplasms, Multiple Primary / pathology. Osteochondroma / pathology

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  • (PMID = 16189321.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Ruan J, Hyjek E, Kermani P, Christos PJ, Hooper AT, Coleman M, Hempstead B, Leonard JP, Chadburn A, Rafii S: Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma. Clin Cancer Res; 2006 Oct 1;12(19):5622-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma.
  • Here, we investigated whether stromal incorporation of CD68(+) hemangiogenic cells and alpha-smooth muscle actin(+) (alpha-SMA(+)) stromal cells correlates with neoangiogenesis and progression in human non-Hodgkin's lymphoma subtypes.
  • EXPERIMENTAL DESIGN: Spatial localizations of vascular and stromal cells expressing CD34, VEGFR-1, alpha-SMA, and CD68 were examined by immunohistochemistry in 42 cases of non-Hodgkin's lymphoma, including diffuse large B-cell lymphoma, Burkitt lymphoma, follicular lymphoma, and chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), and compared with benign follicular hyperplasia.
  • Overall, there was no correlation between CD34(+) microvessel density and lymphoma histologic subtype.
  • CONCLUSIONS: Heightened stromal hemangiogenesis as marked by infiltration of proangiogenic VEGFR-1(+)CD68(+)VEGF-A(+) cells and their paracrine cross-talk with neovasculature appears to be a distinct feature of aggressive lymphoma, providing novel targets for antiangiogenic therapy, whereas alpha-SMA(+) stromal vascular network may be differentially targeted in CLL/SLL.
  • [MeSH-major] Lymphoma, Non-Hodgkin / pathology. Neovascularization, Pathologic / pathology. Stromal Cells / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Aged. Aged, 80 and over. Antigens, CD / metabolism. Antigens, CD34 / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Burkitt Lymphoma / metabolism. Burkitt Lymphoma / pathology. Female. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / metabolism. Leukemia, Lymphocytic, Chronic, B-Cell / pathology. Lymphoma, Follicular / metabolism. Lymphoma, Follicular / pathology. Lymphoma, Large B-Cell, Diffuse / metabolism. Lymphoma, Large B-Cell, Diffuse / pathology. Male. Microcirculation. Middle Aged. Muscle, Smooth / metabolism. Vascular Endothelial Growth Factor A / metabolism. Vascular Endothelial Growth Factor Receptor-1 / metabolism. Vascular Endothelial Growth Factor Receptor-2 / metabolism

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  • (PMID = 17020964.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL 075234; United States / NHLBI NIH HHS / HL / HL 59312; United States / NHLBI NIH HHS / HL / HL 67839; United States / NCRR NIH HHS / RR / K23 RR 016814
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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40. Grzanka AA, Placek W, Grzanka A, Sokolowska-Wojdylo M, Zuryn A: Immunoelectron microscopy in mycosis fungoides and benign dermatoses. Expression of CD3, CD4 and CD7 receptors. Neoplasma; 2010;57(1):41-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunoelectron microscopy in mycosis fungoides and benign dermatoses. Expression of CD3, CD4 and CD7 receptors.
  • Mycosis fungoides is an epidermotropic cutaneous T-cell lymphoma (CTCL).Specimens for presented study were taken from sixteen patients with MF confirmed by immunohistochemical methods and PCR and from nine patients with benign dermatoses.
  • We saw morphological differences between lymphocytes from MF and benign dermatoses.
  • In benign dermatoses the majority of all receptors was present on the cell membrane.
  • KEYWORDS: mycosis fungoides, benign dermatoses, CD3, CD4 and CD7 receptors, immumogold labelling.

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  • (PMID = 19895171.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antigens, CD3; 0 / Antigens, CD4; 0 / Antigens, CD7
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41. Nicholson BT, Harvey JA, Cohen MA: Nipple-areolar complex: normal anatomy and benign and malignant processes. Radiographics; 2009 Mar-Apr;29(2):509-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nipple-areolar complex: normal anatomy and benign and malignant processes.
  • The nipple-areolar complex may be affected by many normal variations in embryologic development and breast maturation as well as by abnormal processes of a benign or malignant nature.
  • Benign processes that may affect the nipple-areolar complex include eczema, duct ectasia, periductal mastitis, adenomas, papillomas, leiomyomas, and abscesses; malignant processes include Paget disease, lymphoma, and invasive and noninvasive breast cancers.
  • Patients may present with benign developmental variations; inversion, retraction, or enlargement of the nipple, which may have either a benign or a malignant cause; a palpable mass; nipple discharge; skin changes in and around the nipple; infection with resultant nipple changes or a subareolar mass; or abnormal findings at routine mammographic screening.

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  • [Copyright] (c) RSNA, 2009.
  • (PMID = 19325062.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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42. Hocke M, Menges M, Topalidis T, Dietrich CF, Stallmach A: Contrast-enhanced endoscopic ultrasound in discrimination between benign and malignant mediastinal and abdominal lymph nodes. J Cancer Res Clin Oncol; 2008 Apr;134(4):473-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Contrast-enhanced endoscopic ultrasound in discrimination between benign and malignant mediastinal and abdominal lymph nodes.
  • EUS-guided fine needle aspiration was performed and cytologic specimens were diagnosed as representing a malignant or benign process in case of Papanicolau IV and V, or Papanicolau I and II, respectively.
  • Using the B-mode criteria the preliminary diagnosis was confirmed in 64 out of 74 benign lymph nodes (specificity 86%).
  • Using the advanced contrast-enhanced EUS criteria the diagnosis was confirmed in 68 of 74 benign lymph nodes (specificity 91%).
  • The contrast-enhanced EUS criteria to identify benign lymph nodes and node enlargement in malignant lymphoma do not differ.
  • If those ten patients with malignant lymphoma are excluded, the sensitivity of the contrast enhanced EUS for malignant lymph nodes rises to 73%.
  • CONCLUSION: Contrast-enhanced EUS improves the specificity in diagnosing benign lymph nodes as compared to B-mode EUS.

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  • (PMID = 17891499.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
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43. Ferreira M, Sanches M, Teixeira M, Guerra M, Selores M: Persistent varicella as the initial manifestation of systemic lymphoma. Dermatol Online J; 2008;14(2):24
MedlinePlus Health Information. consumer health - Chickenpox.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Persistent varicella as the initial manifestation of systemic lymphoma.
  • Varicella is a common benign childhood disease that often presents in adolescents and adults in a more severe form.
  • His poor response to treatment was indicative of immune compromise; an underlying peripheral T-cell lymphoma was discovered.
  • [MeSH-major] Chickenpox / etiology. Lymphoma, T-Cell, Peripheral / complications. Neoplasms, Unknown Primary / diagnosis

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  • (PMID = 18700127.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Przybylik-Mazurek E, Darczuk A, Huszno B, Budzyński A, Rembiasz K, Gałazka K, Wierzchowski W, Giza A, Jurczak W, Skotnicki AB, Sztuk S, Urbanik A: [Primary adrenal lymphoma in incidentally discovered adrenal tumour]. Przegl Lek; 2006;63(8):701-5
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary adrenal lymphoma in incidentally discovered adrenal tumour].
  • In most of cases incidentaloma are benign and gave no clinical signs; however primary adrenal cortex cancer and metastases of different cancers are not uncommon.
  • The primary adrenal lymphoma is an extremely rare disease.
  • The predominant group of patients are men over 50 years with other manifestations of non Hodgkin lymphoma.
  • In our paper we present a case of primary, unilateral lymphoma in a 19 year old women.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / surgery. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / surgery

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  • (PMID = 17441388.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide
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45. Zhai J, Harbour JW, Smith ME, Dávila RM: Correlation study of benign cytomorphology and final clinical diagnosis. Acta Cytol; 2008 Mar-Apr;52(2):196-200
MedlinePlus Health Information. consumer health - Eye Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation study of benign cytomorphology and final clinical diagnosis.
  • OBJECTIVE: To assess significance of cytologically benign vitreous samples and identify cellular patterns that may correspond to specific clinical entities.
  • RESULTS: Fifty-four cytologically benign samples were identified (1994-2004).
  • One had a diagnosis of malignant lymphoma, based on vitreous fluid from the opposite eye at another hospital.
  • CONCLUSION: Most cytologic features of benign vitreous fluids did not correspond to specific clinical entities.
  • Based on our study, negative predictive value of a benign vitreous sample is 98%.

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  • (PMID = 18499993.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Bagheri A, Babsharif B, Yazdani S, Rezaee Kanavi M: Benign reactive lymphoid hyperplasia of the caruncle and plica: report of 5 cases. Ophthal Plast Reconstr Surg; 2007 Nov-Dec;23(6):473-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign reactive lymphoid hyperplasia of the caruncle and plica: report of 5 cases.
  • PURPOSE: To report the clinicopathologic features and management of patients with benign reactive lymphoid hyperplasia of the caruncle and plica semilunaris.
  • CONCLUSIONS: Benign reactive lymphoid hyperplasia should be considered in the differential diagnosis of mass lesions of the caruncle and plica semilunaris, especially in young male patients.
  • Histopathologic evaluation and immunohistochemistry studies are necessary to exclude lymphoma and other malignant lesions.

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  • (PMID = 18030120.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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47. Scheckenbach K, Winterhalter S, Chaker A, Hoffmann TK, Ramp U, Wagenmann M: [MALT lymphoma of the orbit]. HNO; 2008 Feb;56(2):161-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MALT lymphoma of the orbit].
  • [Transliterated title] MALT-Lymphom der Orbita.
  • MALT lymphomas of the orbit are rare orbital tumors; the differential diagnosis needs to exclude inflammatory pseudotumors of the orbit, but also benign lymphoproliferations, pseudolymphomas, and other orbital neoplasms.
  • The clinical picture of MALT lymphoma and its differential diagnosis and treatment are discussed with reference to an actual case.
  • [MeSH-major] Lymphoma, B-Cell, Marginal Zone / diagnosis. Orbital Neoplasms / diagnosis

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  • [Cites] Eur Arch Otorhinolaryngol Suppl. 1993;1:227-53 [8374340.001]
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  • (PMID = 17143610.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD3; 0 / Ki-67 Antigen
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48. Quer M, Pujol A, León X, López M, García J, Orús C, Sañudo JR: Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification. Acta Otorrinolaringol Esp; 2010 Jan-Feb;61(1):1-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification.
  • INTRODUCTION AND GOALS: At present different options co-exist for treating a benign tumour of the parotid gland, which has led to some confusion about the extent of resection performed in each case.
  • METHODS: We analyzed 44 patients who underwent surgery for clinically benign tumours of the parotid gland in our department between July, 2006, and December, 2008.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / surgery. Cysts / surgery. Diagnostic Errors. Female. Humans. Incidental Findings. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, B-Cell, Marginal Zone / surgery. Male. Middle Aged. Parotid Diseases / surgery. Retrospective Studies. Young Adult

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  • [Copyright] 2009 Elsevier España, S.L. All rights reserved.
  • (PMID = 19962123.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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49. Robson A: The pathology of cutaneous T-cell lymphoma. Oncology (Williston Park); 2007 Feb;21(2 Suppl 1):9-12
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The pathology of cutaneous T-cell lymphoma.
  • The diagnosis of cutaneous T-cell lymphoma (CTCL) requires accurate histopathology, including immunocytochemistry, as well as careful clinical appraisal and analysis for T-cell clonality.
  • Clinical information is particularly important in the diagnosis of LyP, as the disease appears malignant histologically, but has a benign clinical course.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17474353.001).
  • [ISSN] 0890-9091
  • [Journal-full-title] Oncology (Williston Park, N.Y.)
  • [ISO-abbreviation] Oncology (Williston Park, N.Y.)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / Antigens, CD4; 0 / Antigens, CD8; 0 / Antigens, Differentiation, T-Lymphocyte
  • [Number-of-references] 1
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50. Blumer SL, Scalcione LR, Ring BN, Johnson R, Motroni B, Katz DS, Yung EY: Cutaneous and subcutaneous imaging on FDG-PET: benign and malignant findings. Clin Nucl Med; 2009 Oct;34(10):675-83

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous and subcutaneous imaging on FDG-PET: benign and malignant findings.
  • However, false-positive interpretations may occur from benign subcutaneous and cutaneous etiologies.
  • Additionally, malignant cutaneous and subcutaneous malignant lesions may also demonstrate substantial F-18 FDG uptake on PET scans, including lymphoma, skin metastases, and melanoma.
  • The purpose of this atlas article is to demonstrate and review key features of various cutaneous and subcutaneous lesions, both benign and malignant, which can result in hypermetabolism on FDG-PET or PET-CT scans.

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  • (PMID = 19893399.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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51. Huber MA, Staib G, Pehamberger H, Scharffetter-Kochanek K: Management of refractory early-stage cutaneous T-cell lymphoma. Am J Clin Dermatol; 2006;7(3):155-69
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of refractory early-stage cutaneous T-cell lymphoma.
  • Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of non-Hodgkin's lymphomas that manifest primarily in the skin.
  • Patients with early-stage CTCL usually have a benign and chronic disease course.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / therapy. Skin Neoplasms / therapy

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  • (PMID = 16734503.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Antineoplastic Agents; 0 / Immunologic Factors; 0 / Retinoids
  • [Number-of-references] 93
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52. Geyer JT, Ferry JA, Harris NL, Young RH, Longtine JA, Zukerberg LR: Florid reactive lymphoid hyperplasia of the lower female genital tract (lymphoma-like lesion): a benign condition that frequently harbors clonal immunoglobulin heavy chain gene rearrangements. Am J Surg Pathol; 2010 Feb;34(2):161-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Florid reactive lymphoid hyperplasia of the lower female genital tract (lymphoma-like lesion): a benign condition that frequently harbors clonal immunoglobulin heavy chain gene rearrangements.
  • Lymphoma-like lesions (LLL) of the lower female genital tract are florid reactive inflammatory processes that mainly occur in women in their reproductive years.
  • Histologically, they are characterized by a dense lymphoid infiltrate with admixed large cells that is often suspicious for lymphoma.
  • In contrast to lymphoma, however, they are superficial lesions that typically show surface erosion and a mixed lymphoid infiltrate and do not have evidence of a mass, deep invasion, or prominent sclerosis.
  • There was no evidence of lymphoma on staging or on follow-up in any patient, including the 4 patients with clonal IGH rearrangement, after a mean follow-up of 3.5 years (range: 4 mo to 13 y).
  • The clinical and pathologic features of these cases suggest that a clonal IGH rearrangement in this setting does not warrant a diagnosis of lymphoma.
  • [MeSH-major] Gene Rearrangement. Immunoglobulin Heavy Chains / genetics. Lymphoma / diagnosis. Pseudolymphoma / diagnosis. Uterine Cervical Diseases / diagnosis. Uterine Diseases / diagnosis

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  • (PMID = 20087162.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin Heavy Chains
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53. Gulmann C, Espina V, Petricoin E 3rd, Longo DL, Santi M, Knutsen T, Raffeld M, Jaffe ES, Liotta LA, Feldman AL: Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma. Clin Cancer Res; 2005 Aug 15;11(16):5847-55
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma.
  • Follicular lymphoma (FL) is the second most common non-Hodgkin's lymphoma and generally is incurable.
  • To determine whether a proteomic approach could help overcome these obstacles, we procured lymphoid follicles from 20 cases of FL and 15 cases of benign follicular hyperplasia (FH) using laser capture microdissection.
  • [MeSH-major] Apoptosis. Lymphoma, Follicular / pathology. Proteome / analysis

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  • (PMID = 16115925.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proteome; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-2 Homologous Antagonist-Killer Protein; 0 / bcl-2-Associated X Protein
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54. Yener S, Ertilav S, Secil M, Akinci B, Demir T, Comlekci A, Yesil S: Natural course of benign adrenal incidentalomas in subjects with extra-adrenal malignancy. Endocrine; 2009 Aug;36(1):135-40
MedlinePlus Health Information. consumer health - Pheochromocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Natural course of benign adrenal incidentalomas in subjects with extra-adrenal malignancy.
  • Patients with extra-adrenal malignancies are diagnosed increasingly with benign adrenal tumors, as well as non-oncology subjects.
  • [MeSH-minor] Adult. Aged. Carcinoma, Non-Small-Cell Lung / epidemiology. Carcinoma, Renal Cell / epidemiology. Disease Progression. Female. Follow-Up Studies. Humans. Incidental Findings. Kidney Neoplasms / epidemiology. Lung Neoplasms / epidemiology. Lymphoma, Non-Hodgkin / epidemiology. Male. Middle Aged. Pancreatic Neoplasms / epidemiology. Prevalence. Registries

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  • [Cites] Arch Surg. 1994 Mar;129(3):291-6 [8129606.001]
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  • (PMID = 19381885.001).
  • [ISSN] 1355-008X
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Martorell M, Gaona Morales JJ, Garcia JA, Manuel Gutierrez Herrera J, Grau FG, Calabuig C, Vallés AP: Transformation of vulvar pseudolymphoma (lymphoma-like lesion) into a marginal zone B-cell lymphoma of labium majus. J Obstet Gynaecol Res; 2008 Aug;34(4 Pt 2):699-705
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transformation of vulvar pseudolymphoma (lymphoma-like lesion) into a marginal zone B-cell lymphoma of labium majus.
  • Diffuse large B-cell lymphoma and follicular lymphoma are the most common types.
  • We describe the case of an 80-year-old woman with a recurrent lesion in the vulva initially diagnosed as a lymphoma-like lesion and evolving 7 years later into a marginal zone B-cell lymphoma (lymphoplasmacytic lymphoma).
  • No previous cases of vulvar marginal zone B-cell lymphoma arising in the context of a persistent lymphoma-like lesion have been reported.
  • We highlight the importance of differentiating benign from malignant lymphoid infiltrates in the vulva.
  • [MeSH-major] Lymphoma, B-Cell, Marginal Zone / pathology. Pseudolymphoma / pathology. Vulva / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 18840185.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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56. Shi H, Guo J, Duff DJ, Rahmatpanah F, Chitima-Matsiga R, Al-Kuhlani M, Taylor KH, Sjahputera O, Andreski M, Wooldridge JE, Caldwell CW: Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis; 2007 Jan;28(1):60-70
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Discovery of novel epigenetic markers in non-Hodgkin's lymphoma.
  • Non-Hodgkin's lymphoma (NHL) is a group of malignancies with heterogeneous genetic and epigenetic alterations.
  • Each gene (DLC-1, PCDHGB7, CYP27B1, EFNA5, CCND1 and RARbeta2) was frequently hypermethylated in these NHLs (87, 78, 61, 53, 40 and 38%, respectively), but not in benign follicular hyperplasia.
  • [MeSH-major] Biomarkers, Tumor / genetics. DNA Methylation. Epigenesis, Genetic. Gene Expression Regulation, Neoplastic. Lymphoma, Non-Hodgkin / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Blotting, Western. CpG Islands. GTPase-Activating Proteins. Gene Expression Profiling. Genome, Human. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / genetics. Leukemia, Lymphocytic, Chronic, B-Cell / metabolism. Leukemia, Lymphocytic, Chronic, B-Cell / pathology. Lymphoma, B-Cell / genetics. Lymphoma, B-Cell / metabolism. Lymphoma, B-Cell / pathology. Lymphoma, Large B-Cell, Diffuse / genetics. Lymphoma, Large B-Cell, Diffuse / metabolism. Lymphoma, Large B-Cell, Diffuse / pathology. Microarray Analysis. Middle Aged. Promoter Regions, Genetic. Reverse Transcriptase Polymerase Chain Reaction. Tumor Suppressor Proteins / genetics. Tumor Suppressor Proteins / metabolism

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  • (PMID = 16774933.001).
  • [ISSN] 0143-3334
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA097880; United States / NCI NIH HHS / CA / CA100055; United States / NCI NIH HHS / CA / P50 CA097274
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DLC1 protein, human; 0 / GTPase-Activating Proteins; 0 / Tumor Suppressor Proteins
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57. O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L, Fleischmann C, Mein CA, Crook T, Smith P, Kelly G, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Johnson N, Gascoyne RD, Reimer S, Braziel RM, Wright GW, Staudt LM, Lister TA, Fitzgibbon J: Array-based DNA methylation profiling in follicular lymphoma. Leukemia; 2009 Oct;23(10):1858-66
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  • [Title] Array-based DNA methylation profiling in follicular lymphoma.
  • Quantitative methylation profiling was performed using the Illumina GoldenGate Assay in untreated follicular lymphoma (FL) (164), paired pre- and post-transformation FL (20), benign haematopoietic (24) samples and purified B and T cells from two FL cases.
  • [MeSH-major] DNA Methylation. Gene Expression Profiling. Lymph Nodes / pathology. Lymphoma, Follicular / genetics. Oligonucleotide Array Sequence Analysis

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  • (PMID = 19587707.001).
  • [ISSN] 1476-5551
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U01 CA114778; United Kingdom / Cancer Research UK / / A9424; United Kingdom / Cancer Research UK / / A8314; United Kingdom / Medical Research Council / / ; United States / NCI NIH HHS / CA / 5 U01 CA114778; United Kingdom / Cancer Research UK / / MONG1E9R
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2762475; NLM/ UKMS4607
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58. Lu JB, Li XQ, Zhu XZ: [Distinction between lymphoma-like lesions and lymphoma of uterine cervix: a clinicopathologic study of 26 cases]. Zhonghua Bing Li Xue Za Zhi; 2007 May;36(5):297-301
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  • [Title] [Distinction between lymphoma-like lesions and lymphoma of uterine cervix: a clinicopathologic study of 26 cases].
  • OBJECTIVE: To study the clinicopathologic features and differential diagnosis of lymphoma-like lesions and lymphoma of uterine cervix.
  • METHODS: Clinical data and hematoxylin and eosin-stained slides of 10 cases of lymphoma-like lesion and 16 cases of lymphoma of uterine cervix were reviewed.
  • The rearrangement status of immunoglobulin heavy chain (IgH) gene was analyzed with semi-nested polymerase chain reaction in 4 cases lymphoma-like lesion and 4 cases of lymphoma of uterine cervix.
  • RESULTS: The age of patients with lymphoma-like lesion ranged from 24 to 54 years (medium = 43 years).
  • On the other hand, the age of the patients with lymphoma of uterine cervix varied from 28 to 78 years (medium = 58 years).
  • The cases included 12 examples of diffuse large B-cell lymphoma and 4 examples of follicular lymphoma.
  • Molecular study showed clonal rearrangement of IgH gene in all cases of cervical lymphoma, as well as 2 cases of lymphoma-like lesion.
  • CONCLUSIONS: The distinction between lymphoma-like lesion and lymphoma of uterine cervix depends primarily on the clinical and histopathologic features.
  • Assay for rearrangement of IgH gene may be helpful in differential diagnosis, though monoclonality can be detected in some benign lesions as well.
  • [MeSH-major] Lymphoma, Follicular / pathology. Lymphoma, Large B-Cell, Diffuse / pathology. Polyps / pathology. Uterine Cervical Erosion / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 17706135.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD79; 0 / CD79A protein, human; 0 / Immunoglobulin G
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59. Erly WK, Oh ES, Outwater EK: The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine. AJNR Am J Neuroradiol; 2006 Jun-Jul;27(6):1183-8
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  • [Title] The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine.
  • BACKGROUND AND PURPOSE: Benign and malignant fractures of the spine may have similar signal intensity characteristics on conventional MR imaging sequences.
  • METHODS: Twenty-five consecutive patients who were evaluated for suspected malignancy (lymphoma [4 patients], breast cancer [3], multiple myeloma [2], melanoma [2], prostate [2], and renal cell carcinoma [1]) or for trauma to the thoracic or lumbar spine were entered into this study.
  • RESULTS: Twenty-one patients had 49 vertebral lesions, consisting of 20 malignant and 29 benign fractures.
  • There was a significant difference (P < .001, Student t test) in the mean SIR for the benign lesions (mean, 0.58; SD, 0.02) compared with the malignant lesions (mean, 0.98; SD, 0.095).
  • If a SIR of 0.80 as a cutoff is chosen, with >0.8 defined as malignant and <0.8 defined as a benign result, in-phase/opposed-phase imaging correctly identified 19 of 20 malignant lesions and 26 of 29 benign lesions (sensitivity, 0.95; specificity, 0.89).
  • CONCLUSION: There is significant difference in signal intensity between benign compression fractures and malignancy on in-phase/opposed-phase MR imaging.

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  • (PMID = 16775260.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Sharon V, Mecca PS, Steinherz PG, Trippett TM, Myskowski PL: Two pediatric cases of primary cutaneous B-cell lymphoma and review of the literature. Pediatr Dermatol; 2009 Jan-Feb;26(1):34-9
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  • [Title] Two pediatric cases of primary cutaneous B-cell lymphoma and review of the literature.
  • Primary cutaneous B-cell lymphoma has rarely been reported in children, and in the past may have been mistaken for disseminated nodal disease or benign cutaneous lymphoid hyperplasias.
  • We describe two cases of marginal zone primary cutaneous B-cell lymphoma in young males.
  • [MeSH-major] Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / therapy. Skin / pathology. Skin Neoplasms / pathology. Skin Neoplasms / therapy

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  • (PMID = 19250402.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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61. Anderson L, Middleton WD, Teefey SA, Reading CC, Langer JE, Desser T, Szabunio MM, Mandel SJ, Hildebolt CF, Cronan JJ: Hashimoto thyroiditis: Part 2, sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis. AJR Am J Roentgenol; 2010 Jul;195(1):216-22
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  • [Title] Hashimoto thyroiditis: Part 2, sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis.
  • OBJECTIVE: The purpose of this article is to compare sonographic features of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis.
  • Patients with a sonographic appearance consistent with diffuse Hashimoto thyroiditis and with coexisting nodules that could be confirmed to be benign or malignant by fine-needle aspiration or surgical pathologic analysis were included in the study.
  • RESULTS: Among nodules within diffuse Hashimoto thyroiditis, 84% (69/82) were benign (35 nodular Hashimoto thyroiditis, 32 nodular hyperplasia, and two follicular adenoma), and 16% (13/82) were malignant (12 papillary carcinoma and one lymphoma).
  • Benign nodules were more likely to be hyperechoic (46% vs 9%), to have a halo (39% vs 15%), and to lack calcifications (88% vs 23%).
  • Benign nodules more often had ill-defined margins (36% vs 8%).
  • CONCLUSION: Sonographic features of benign and malignant nodules within diffuse Hashimoto thyroiditis are generally similar to the features typical of benign and malignant nodules in the general population.

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  • (PMID = 20566819.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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62. Bennett LB, Schnabel JL, Kelchen JM, Taylor KH, Guo J, Arthur GL, Papageorgio CN, Shi H, Caldwell CW: DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma. Genes Chromosomes Cancer; 2009 Sep;48(9):828-41
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  • [Title] DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma.
  • High-throughput microarray technologies were used to study DNA methylation accompanied by transcriptional changes in follicular lymphoma (FL).
  • Using Methylated CpG Island Amplification with Microarrays to study CpG Island DNA methylation in FL, we discovered widespread hypermethylation of homeobox genes and previously identified targets of polycomb repressive complex 2 (PRC2) in cell lines and primary tumors, but not in benign follicular hyperplasia (BFH).

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  • (PMID = 19530241.001).
  • [ISSN] 1098-2264
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA10055; United States / NCI NIH HHS / CA / R03 CA123565; United States / NCI NIH HHS / CA / R33 CA097880; United States / NCI NIH HHS / CA / R03 CA123565-02; United States / NCI NIH HHS / CA / CA100055-04; United States / NCI NIH HHS / CA / CA097880; United States / NCI NIH HHS / CA / R21 CA123018; United States / NCI NIH HHS / CA / CA123565-02; United States / NCI NIH HHS / CA / R21 CA123018-02; United States / NCI NIH HHS / CA / R21 CA097880; United States / NCI NIH HHS / CA / CA123018-02; United States / NCI NIH HHS / CA / R33 CA097880-05; United States / NCI NIH HHS / CA / R01 CA100055; United States / NCI NIH HHS / CA / CA123018; United States / NCI NIH HHS / CA / CA097880-05; United States / NCI NIH HHS / CA / R01 CA100055-04; United States / NCI NIH HHS / CA / CA123565
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCND1 protein, human; 0 / Carrier Proteins; 0 / HOXA11 protein, human; 0 / Homeodomain Proteins; 0 / Nuclear Proteins; 0 / Polycomb-Group Proteins; 0 / Repressor Proteins; 0 / SUZ12 protein, human; 136601-57-5 / Cyclin D1; EC 2.1.1.43 / Polycomb Repressive Complex 2
  • [Other-IDs] NLM/ NIHMS125568; NLM/ PMC2738630
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63. Lazzareschi I, Barone G, Ruggiero A, Liotti L, Maurizi P, Larocca LM, Riccardi R: Paediatric Kikuchi-Fujimoto disease: a benign cause of fever and lymphadenopathy. Pediatr Blood Cancer; 2008 Jan;50(1):119-23
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  • [Title] Paediatric Kikuchi-Fujimoto disease: a benign cause of fever and lymphadenopathy.
  • Kikuchi-Fujimoto disease (KFD) is a rare and benign disease that typically affects the cervical lymph nodes.
  • No specific management is generally required but long-term follow-up should be planned despite the low risk of recurrence, as recurrences have been described many years after the first episode and there is a high risk of development of an autoimmune disease or even lymphoma.

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 16755552.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Su MG, Fan QP, Tian Y, Li FL, Yang XC, Li L, Fan CZ, Tian R: [Differentiation of malignant and benign superficial lymph nodes by dual time point 18F-FDG PET]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2009 May;40(3):517-20
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  • [Title] [Differentiation of malignant and benign superficial lymph nodes by dual time point 18F-FDG PET].
  • OBJECTIVE: To evaluate the value of dual time point 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in differentiating malignant and benign superficial lymph nodes.
  • RESULTS: The histopathology examinations confirmed 51 malignant nodes and 39 benign nodes.
  • The SUV early (x +/- s) for benign nodes and malignant nodes were 3.26 +/- 1.62 and 8.04 +/- 5.56, respectively (P=0.000).
  • The SUV delayed for benign nodes and malignant nodes were 3.93 +/- 2.11 and 9.82 +/- 6.29, respectively (P=0.000).
  • The RI for benign nodes and malignant nodes were 19.1 +/- 22.5 and 24.8 +/- 18.8, respectively (P=0.191).
  • CONCLUSION: Dual-time point 18F-FDG PET does differentiate benign and malignant superficial lymph nodes effectively.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphoma / radionuclide imaging. Male. Middle Aged. Radiopharmaceuticals. Young Adult

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  • (PMID = 19627018.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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65. Escobosa Sánchez OM, Herrero Hernández A, Acha García T: [Endobronchial anaplastic large cell lymphoma in childhood]. An Pediatr (Barc); 2009 May;70(5):449-52
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  • [Title] [Endobronchial anaplastic large cell lymphoma in childhood].
  • [Transliterated title] Linfoma anaplásico de células grandes endobronquial en la infancia.
  • Anaplastic large cell lymphoma is a very rare disease in childhood.
  • The most common location of this lymphoma is lymph node and skin, with endobronchial involvement being extremely rare.
  • We report a case of a 10-year-old boy diagnosed by chance with an endobronchial anaplastic large cell lymphoma, while he was being investigated for a a benign bone disease, due to the initial absence of respiratory symptoms.
  • [MeSH-major] Bronchial Neoplasms. Lymphoma, Large-Cell, Anaplastic

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  • (PMID = 19375996.001).
  • [ISSN] 1695-4033
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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66. Nakase K, Yamamoto K, Hiasa A, Tawara I, Yamaguchi M, Shiku H: Contrast-enhanced ultrasound examination of lymph nodes in different types of lymphoma. Cancer Detect Prev; 2006;30(2):188-91
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  • [Title] Contrast-enhanced ultrasound examination of lymph nodes in different types of lymphoma.
  • BACKGROUND: Since the tumor growth depends on the formation of feeding vessels, color/power Doppler ultrasonography (US) has been used to evaluate the vascular flow images of lymph nodes (LNs) in order to differentiate benign LNs from malignant LNs or lymphoma from metastatic carcinoma.
  • METHODS: We performed color/power Doppler ultrasonography (US) using Levovist (LV) to evaluate the vascular patterns in the LNs of 10 patients with different types of lymphoma.
  • The vascular pattern of the LNs was of the central type in all seven B-cell lymphoma patients and one of two T-cell lymphoma patients and of the peripheral type in the remaining T-cell lymphoma patient.
  • The avascular type pattern was observed in one Hodgkin lymphoma patient even with LV.
  • DISCUSSION: Typical vascular patterns might be associated with certain subtypes of lymphoma, and LV appears to improve the diagnostic value of Doppler US.
  • [MeSH-major] Lymph Nodes / ultrasonography. Lymphatic Vessels / ultrasonography. Lymphoma / ultrasonography

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  • (PMID = 16632242.001).
  • [ISSN] 0361-090X
  • [Journal-full-title] Cancer detection and prevention
  • [ISO-abbreviation] Cancer Detect. Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Polysaccharides; 127279-08-7 / SHU 508
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67. Hagspiel KD: Manifestation of Hodgkin's lymphoma in an adrenal myelolipoma. Eur Radiol; 2005 Aug;15(8):1757-9
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  • [Title] Manifestation of Hodgkin's lymphoma in an adrenal myelolipoma.
  • Adrenal myelolipomas are benign tumors histologically consisting of fat and bone marrow.
  • The computed tomography findings of Hodgkin's lymphoma manifested in an adrenal myelolipoma are described.

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  • [Cites] Clin Radiol. 2002 Nov;57(11):1034-7 [12409116.001]
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  • (PMID = 15503042.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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68. van Besien K, Schouten H: Follicular lymphoma: a historical overview. Leuk Lymphoma; 2007 Feb;48(2):232-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Follicular lymphoma: a historical overview.
  • Lymphoma was first described in 1862 and follicular lymphoma in 1925.
  • Initially considered a benign disorder, and named Brill - Symmers disease after the authors of the original papers, it was rapidly recognized as a malignancy with a variable but often indolent course.
  • Despite discussion about its cell of origin, and in contrast to many other lymphoma subtypes, follicular lymphoma could always be accurately recognized and diagnosed using light microscopy morphological features.
  • B-cell origin was demonstrated in the 1970s and the important role of t(14;18) and bcl-2 gene rearrangement in the pathogenesis of follicular lymphoma was established shortly thereafter.
  • The etiology of follicular lymphoma, the reason for marked geographic variation in its incidence, the role of alternative molecular pathways in its pathogenesis, and the cause for its variable clinical behavior all remain unknown.
  • Several observations suggest an important role for the normal immune response in regulating the clinical behavior of follicular lymphoma.
  • From the earliest descriptions, radiation therapy was shown to be very effective in follicular lymphoma, but not curative.
  • Targeted therapies, particularly rituximab have revolutionized the treatment of follicular lymphoma.
  • For the first time consistent improvements in survival of follicular lymphoma are reported.
  • [MeSH-major] Lymphoma, Follicular / history

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  • (PMID = 17325883.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] England
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69. Bi R, Lin DM, Han YL, Lu J, Xue LY, Zheng S, Wang MR, Lü N: [Application of interphase fluorescence in situ hybridization in the diagnosis of lymphoma]. Zhonghua Bing Li Xue Za Zhi; 2009 Nov;38(11):733-8
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  • [Title] [Application of interphase fluorescence in situ hybridization in the diagnosis of lymphoma].
  • METHODS: A total of 74 fresh tissue samples clinically suspicious of lymphoma were investigated by FISH using three probes including IgH/bcl-2, IgH/CCND1 and API2/MALT1, corresponding the translocation t(14;18), t(11;14) and t(11;18) respectively.
  • RESULTS: Histological evaluation eventually confirmed that there were 62 cases of lymphoma and 12 cases of reactive lymphoid processes.
  • The translocations were detected in 7 cases in 62 cases of lymphoma: 3 demonstrated t(14;18) including 2 cases of follicular lymphomas and 1 nodular sclerosing Hodgkin lymphoma.
  • Four cases had t(11;14) including mantle cell lymphoma (2 cases), follicular lymphoma (1 case) and small cell lymphoma (1 case).
  • Amplification or loss of regional genes was seen more often in malignant than in the benign cases.
  • CONCLUSION: Interphase FISH offers useful ancillary technology that plays an important role in differential diagnosis and classification of lymphoma.
  • [MeSH-major] In Situ Hybridization, Fluorescence / methods. Lymphoma / diagnosis. Translocation, Genetic
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 14. Chromosomes, Human, Pair 18. Diagnosis, Differential. Female. Hodgkin Disease / diagnosis. Hodgkin Disease / genetics. Hodgkin Disease / pathology. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis. Leukemia, Lymphocytic, Chronic, B-Cell / genetics. Leukemia, Lymphocytic, Chronic, B-Cell / pathology. Lymphoma, Follicular / diagnosis. Lymphoma, Follicular / genetics. Lymphoma, Follicular / pathology. Lymphoma, Large B-Cell, Diffuse / diagnosis. Lymphoma, Large B-Cell, Diffuse / genetics. Lymphoma, Large B-Cell, Diffuse / pathology. Lymphoma, Mantle-Cell / diagnosis. Lymphoma, Mantle-Cell / genetics. Lymphoma, Mantle-Cell / pathology. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / genetics. Lymphoma, Non-Hodgkin / pathology. Male. Middle Aged. Young Adult

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  • (PMID = 20079011.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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70. Goshen E, Davidson T, Avigdor A, Zwas TS, Levy I: PET/CT in the evaluation of lymphoma in patients with HIV-1 with suppressed viral loads. Clin Nucl Med; 2008 Sep;33(9):610-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] PET/CT in the evaluation of lymphoma in patients with HIV-1 with suppressed viral loads.
  • Patients with HIV-1 are at risk for lymphoma, making the differential diagnosis between benign and malignant lymphadenopathy imperative.
  • This study retrospectively evaluated the role of PET/computed tomography (CT) in differentiating active lymphoma from persistent generalized lymphadenopathy in patients with HIV-1.
  • Six, with known non-Hodgkin lymphoma underwent a total of 16 PET/CT scans; 5/16 scans were performed for initial staging, and 10/16 for evaluating treatment response and follow-up.
  • One patient was referred for evaluation of lymphadenopathy suspected of being lymphoma.
  • RESULTS: PET/CT accurately depicted the extent of lymphoma in 12/16 patients' scans (75%), yet in 4/16 (25%) scans increased fluorodeoxyglucose uptake was noted in lymph nodes of normal CT appearance (PET+/CT-).
  • The PET+/CT- findings in both these patients were observed in neck, axillae, mediastinum, spleen, and inguinal regions, and sample biopsies of the PET (+) nodes consequently proved benign findings in both patients.
  • All PET+/CT+ findings correctly indicated lymphoma status, as proven by clinical follow-up.
  • CONCLUSION: PET/CT accurately detected lymphoma in patients with HIV-1 and had been used confidently as a management tool in this patient group.
  • In the context of discrepant PET/CT findings, increased viral loads and CD4 levels may imply benign HIV-related lymphadenopathy.
  • [MeSH-major] HIV Infections / complications. HIV Infections / virology. Lymphoma / complications. Lymphoma / diagnosis. Viral Load

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  • (PMID = 18716509.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Rutherford SC, Andemariam B, Philips SM, Elstrom RL, Chadburn A, Furman RR, Niesvizky R, Martin P, Fahey TJ, Coleman M, Goldsmith SJ, Leonard JP: FDG-PET in prediction of splenectomy findings in patients with known or suspected lymphoma. Leuk Lymphoma; 2008 Apr;49(4):719-26
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  • [Title] FDG-PET in prediction of splenectomy findings in patients with known or suspected lymphoma.
  • Diagnostic splenectomy is frequently performed in patients with suspected or known lymphoma.
  • Of 165 patients undergoing splenectomy at the Weill Cornell Medical Centre/New York Presbyterian Hospital from 2004 to 2006, 10 were identified as being performed to evaluate known or suspected lymphoma and included a pre-splenectomy FDG-PET scan.
  • Low activity was associated with benign findings or mantle cell lymphoma at splenectomy, intermediate activity with marginal zone lymphoma and high activity with DLBCL.
  • This comprises the largest pathologically confirmed series of cases to evaluate splenic FDG-PET uptake in suspected or known lymphoma.
  • Low splenic SUV appears less likely to be associated with splenic involvement of lymphoma; intermediate and high values suggest presence of lymphoma.
  • [MeSH-major] Fluorodeoxyglucose F18 / pharmacokinetics. Lymphoma, Non-Hodgkin / diagnosis. Positron-Emission Tomography / methods. Splenectomy

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  • (PMID = 18398739.001).
  • [ISSN] 1029-2403
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / K23 RR16814
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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72. Peng ZM, Liu Q, Liu QW, Yao SZ, Meng L, Liu Q, Chen JH: [The value of dual time point 11C-choline PET-CT in differentiating malignant from benign lesion of mediastinum]. Zhonghua Yi Xue Za Zhi; 2007 Dec 18;87(47):3317-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The value of dual time point 11C-choline PET-CT in differentiating malignant from benign lesion of mediastinum].
  • OBJECTIVE: To evaluate the value of dual time point 11C-choline PET-CT in differentiating malignant from benign lesions of mediastinum.
  • RESULTS: Eleven of the 35 patients with mediastinal diseases were diagnosed as with sarcoidosis, 6 with tuberculosis, 5 with lymphoma, 11 with nodal metastasis (8 had their modes from the lung and the primary lesions of the other 3 failed to be identified), and 2 with lung cancer with reactive hyperplasia lymph node.
  • The value of SUV of delayed images of the 19 benign lesions was 4.99 (2.2-9.3), lower than that of early images [5.11 (2.9-8.3)] with a DeltaSUV of -0.12 (-0.9-1.0).
  • The DeltaSUV of the benign lesions was significantly lower than that of the malignant lesions (F = 1.939, P = 0.04).
  • Conclusion With a high diagnostic yield, videomediastinoscopy remains the gold standard in differentiation of malignant and benign lesions located in the middle mediastinum.

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  • (PMID = 18478942.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Carbon Radioisotopes; N91BDP6H0X / Choline
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73. Roca B, Vidal-Tegedor B, Moya M: Primary non-hodgkin lymphoma of the larynx. South Med J; 2005 Mar;98(3):388-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary non-hodgkin lymphoma of the larynx.
  • A rare case of primary large B-cell non-Hodgkin lymphoma of the larynx is reported.
  • Although cases of aggressive course and poor response to therapy exist, primary large B-cell non-Hodgkin lymphoma of the larynx is generally considered a relatively benign and radiosensitive tumor.
  • [MeSH-major] Laryngeal Neoplasms / radiotherapy. Lymphoma, B-Cell / radiotherapy

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  • (PMID = 15813168.001).
  • [ISSN] 0038-4348
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Hunt BM, Vallières E, Buduhan G, Aye R, Louie B: Sarcoidosis as a benign cause of lymphadenopathy in cancer patients. Am J Surg; 2009 May;197(5):629-32; discussion 632
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sarcoidosis as a benign cause of lymphadenopathy in cancer patients.
  • This association makes the cancer patient with lymphadenopathy a diagnostic dilemma: malignant involvement of the lymph nodes is common, but benign diagnoses are possible and must be considered.
  • [MeSH-major] Breast Neoplasms / epidemiology. Lung Neoplasms / epidemiology. Lymphatic Diseases / etiology. Lymphoma, Non-Hodgkin / epidemiology. Sarcoidosis / complications. Testicular Neoplasms / epidemiology


75. Asoglu O, Porter L, Donohue JH, Cha SS: Laparoscopy for the definitive diagnosis of intra-abdominal lymphoma. Mayo Clin Proc; 2005 May;80(5):625-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopy for the definitive diagnosis of intra-abdominal lymphoma.
  • OBJECTIVE: To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma.
  • PATIENTS AND METHODS: The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed.
  • Among the 69 cases of lymphoma, 55 (80%) were diagnosed via laparoscopy only, 9 (13%) via laparotomy, and 5 (7%) with later procedures.
  • Of the remaining 25 patients, 7 had nonlymphoma disease (4 occult carcinomas, 1 multiple myeloma, 1 epithelioid leiomyosarcoma, and 1 neuroblastoma), and 18 had benign lymphadenopathy (no evidence of lymphoma with a mean follow-up of 53 months).
  • CONCLUSION: Laparoscopic lymph node biopsy safely provides adequate tissue for full histological evaluation on an outpatient basis in most patients with intra-abdominal lymphoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy / methods. Diagnosis, Differential. False Negative Reactions. Feasibility Studies. Female. Follow-Up Studies. Humans. Laparotomy. Lymphoma, Non-Hodgkin / pathology. Lymphoma, Non-Hodgkin / surgery. Male. Middle Aged. Reproducibility of Results. Retrospective Studies. Safety

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  • (PMID = 15887430.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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76. Riehl G, Aubert A, Sandu C, Brichon PY: Malignant non-Hodgkin's lymphoma developing late after pneumonectomy. Eur J Cardiothorac Surg; 2006 Dec;30(6):948-9

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  • [Title] Malignant non-Hodgkin's lymphoma developing late after pneumonectomy.
  • A 64-year-old man underwent a left pneumonectomy for a benign bronchial stenosis in 1968.
  • In 1997, a left parietal thoracic tumour: T-type malignant non-Hodgkin's lymphoma (MNHL) was detected.
  • We have found only one case of such a lymphoma in the literature.
  • It could be classified as pyothorax-associated lymphoma from which there are several published cases especially in Japanese literature.
  • [MeSH-major] Lymphoma, T-Cell / etiology. Pleural Neoplasms / etiology. Pneumonectomy / adverse effects

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  • (PMID = 17046274.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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77. Strömberg S, Agnarsdóttir M, Magnusson K, Rexhepaj E, Bolander A, Lundberg E, Asplund A, Ryan D, Rafferty M, Gallagher WM, Uhlen M, Bergqvist M, Ponten F: Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma. J Proteome Res; 2009 Apr;8(4):1639-46
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  • [Title] Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma.
  • In tumor tissues, STX7 was expressed in malignant melanoma and lymphoma.
  • STX7 was expressed in normal melanocytes, various benign melanocytic nevi, atypical nevi and malignant melanoma.

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  • (PMID = 19714869.001).
  • [ISSN] 1535-3893
  • [Journal-full-title] Journal of proteome research
  • [ISO-abbreviation] J. Proteome Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Qa-SNARE Proteins
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78. Martínez De Pablo MI, Iranzo P, Mascaró JM, Llambrich A, Baradad M, Herrero C: Paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma and good response to prednisone. Acta Derm Venereol; 2005;85(3):233-5
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  • [Title] Paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma and good response to prednisone.
  • These cases were generally associated with benign neoplasms.
  • We report here the case of a patient with paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma who had a surprisingly good response to systemic corticosteroids and remains free of lesions more than 3 years later despite progression of her neoplasm.
  • [MeSH-major] Lymphoma, B-Cell / diagnosis. Paraneoplastic Syndromes / diagnosis. Pemphigus / diagnosis

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  • (PMID = 16040408.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Glucocorticoids; VB0R961HZT / Prednisone
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79. Sands NB, Tewfik MA, Hwang SY, Desrosiers M: Extranodal T-cell lymphoma of the sinonasal tract presenting as severe rhinitis: case series. J Otolaryngol Head Neck Surg; 2008 Aug;37(4):528-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extranodal T-cell lymphoma of the sinonasal tract presenting as severe rhinitis: case series.
  • One clinical entity that mimics severe rhinitis and thus poses a particular challenge in this regard is extranodal T-cell lymphoma of the sinonasal tract.
  • Sinonasal lymphoma has a vague initial presentation that masquerades as more common, benign causes of rhinitis but progresses as a "midfacial progressive destructive lesion" and is uniformly fatal if untreated.
  • Each patient presented initially with severe rhinitis but was later diagnosed with extranodal natural killer/T-cell non-Hodgkin lymphoma of the sinonasal tract.
  • CONCLUSION: The challenge in making an early diagnosis of T-cell lymphoma of the sinonasal tract has been reaffirmed in our case series.
  • [MeSH-major] Lymphoma, T-Cell / diagnosis. Paranasal Sinus Neoplasms / diagnosis

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  • (PMID = 19128588.001).
  • [ISSN] 1916-0216
  • [Journal-full-title] Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
  • [ISO-abbreviation] J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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80. Whitt JC, Dunlap CL, Martin KF: Oral Hodgkin lymphoma: a wolf in wolf's clothing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Nov;104(5):e45-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oral Hodgkin lymphoma: a wolf in wolf's clothing.
  • Hodgkin lymphoma typically presents as a nodal lesion and infrequently involves extranodal sites.
  • The English language literature contains only 7 reports of primary Hodgkin lymphoma arising in the oral mucosa in the absence of nodal disease.
  • We report a case of primary, extranodal Hodgkin lymphoma in the palatal mucosa of a 79-year-old white female.
  • An incisional biopsy revealed a diffuse, mixed cellular infiltrate, consisting of benign lymphocytes, plasma cells, histiocytes, and foci rich in eosinophils.
  • Within this background was a scattering of large, atypical cells, including Reed-Sternberg forms that exhibited immunoreactivity for CD30 and CD20 and nonreactivity for CD15 and CD45RO, supporting a diagnosis of classical Hodgkin lymphoma.

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  • (PMID = 17964472.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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81. Yazbeck V, Georgakis GV, Wedgwood A, Younes A: Hodgkin's lymphoma: molecular targets and novel treatment strategies. Future Oncol; 2006 Aug;2(4):533-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hodgkin's lymphoma: molecular targets and novel treatment strategies.
  • The WHO classification of Hodgkin's lymphoma (HL) distinguishes between two major subtypes, classical and nodular lymphocyte predominant HL.
  • Approximately 95% of patients with HL will have the classical HL histology, which is characterized by the presence of rare malignant Hodgkin's and Reed-Sternberg cells among an overwhelming number of benign reactive cells.

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  • (PMID = 16922620.001).
  • [ISSN] 1479-6694
  • [Journal-full-title] Future oncology (London, England)
  • [ISO-abbreviation] Future Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 198
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82. Vonderheid EC: On the diagnosis of erythrodermic cutaneous T-cell lymphoma. J Cutan Pathol; 2006 Feb;33 Suppl 1:27-42
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  • [Title] On the diagnosis of erythrodermic cutaneous T-cell lymphoma.
  • Erythrodermic cutaneous T-cell lymphoma (E-CTCL) is the cause of less than 5% of all cases of generalized erythroderma.
  • In this commentary, the author discusses available information regarding the role of these diagnostic methods for the diagnosis of E-CTCL with emphasis on personal observations regarding skin IHC and polymerase chain reaction (PCR)-based molecular studies as adjunct diagnostic studies on a series of 55 patients with erythrodermic mycosis fungoides and 50 patients with Sézary syndrome compared to 50 patients with extensive benign inflammatory skin disease.
  • The conclusions are (1) IHC of the skin does not reliably differentiate E-CTCL from benign simulants, (2) presence of phenotypically abnormal T cells in the blood or expanded subsets of CD4+CD7- or CD4+CD26- cells by FC is particularly helpful as a diagnostic study, (3) the presence of an identical T-cell clone in the skin and blood also is a specific diagnostic criterion for E-CTCL, but exceptions may occur, and (4) the PCRgamma-denaturing gradient gel electrophoresis technique appears to be more reliable than PCRgamma-single-stranded conformational polymorphism for diagnostic purposes.
  • [MeSH-major] Dermatitis, Exfoliative / diagnosis. Lymphoma, T-Cell, Cutaneous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16412210.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 107
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83. Chang H, Gao Y, Zhang JY, Shi F, Chen YZ: [Expression of survivin and NF-kappaB in peripheral T-cell lymphoma and its significance]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2008 Oct;16(5):1079-81
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  • [Title] [Expression of survivin and NF-kappaB in peripheral T-cell lymphoma and its significance].
  • This study was aimed to explore the expression of survivin and NF-kappaB in the peripheral T-cell lymphoma and its significance.
  • 30 cases of benign reactive lymphohistiocytosis were selected as control tor analysis.
  • The results showed that the expression of survivin in 21 patients with lymphoma was positive, the positive rate reached to 80.8%; the expression of NF-kappaB in 17 cases was positive, the positive rate reached to 65.4%.
  • It is concluded that survivin and NF-kappaB widely expressed in lymphoma cells and they play an important role in enhancing proliferation and inhibiting apoptosis of tumor cells.

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  • (PMID = 18928599.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / NF-kappa B
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84. Jin Y, Li YC, Su ZL, Tang LY, Feng ZY, Guo SZ: [Protein expressions of Fas and FasL in B-cell lymphoma and their significances]. Ai Zheng; 2005 Mar;24(3):332-6
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  • [Title] [Protein expressions of Fas and FasL in B-cell lymphoma and their significances].
  • This study was designed to detect protein expressions of Fas and FasL in B-cell non-Hodgkin's lymphoma (B-NHL) and benign lymphoid tissue, and to provide new markers for diagnosis of lymphoma.
  • METHODS: Immunohistochemistry was used to detect protein expressions of Fas and FasL in 92 specimens of B-NHL, and 20 specimens of benign lymphoid tissue.
  • Positive rates of both Fas and FasL in benign lymphoid tissue were 60.0% (12/20).
  • There was no significant difference in expressions of Fas and FasL between B-NHL group and benign group (P>0.05), but positive locations of Fas and FasL in these 2 groups are different.
  • Positive rates of Fas and FasL were higher in diffuse large B-cell lymphoma (DLBL) than in follicular lymphoma (FL), and small cell lymphoma (SLL) (87.2% vs. 64.5%, and 31.8%, P<0.05u 89.7% vs. 67.7%, and 27.3%, P<0.05).
  • CONCLUSIONS: The expressions of Fas and FasL are not useful for distinguishing benign lymphoid tissue from lymphoma tissue, while their locational characteristics are valuable for differential diagnosis.
  • [MeSH-major] Antigens, CD95 / metabolism. Lymphoma, B-Cell / metabolism. Lymphoma, Follicular / metabolism. Lymphoma, Large B-Cell, Diffuse / metabolism. Membrane Glycoproteins / metabolism. Tumor Necrosis Factors / metabolism

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  • (PMID = 15757536.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD95; 0 / Biomarkers, Tumor; 0 / FASLG protein, human; 0 / Fas Ligand Protein; 0 / Membrane Glycoproteins; 0 / Tumor Necrosis Factors
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85. Hui D, Reiman T, Hanson J, Linford R, Wong W, Belch A, Lai R: Immunohistochemical detection of cdc2 is useful in predicting survival in patients with mantle cell lymphoma. Mod Pathol; 2005 Sep;18(9):1223-31
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  • [Title] Immunohistochemical detection of cdc2 is useful in predicting survival in patients with mantle cell lymphoma.
  • Recent cDNA microarray studies have reported the prognostic value of several genes in mantle cell lymphoma patients.
  • Their immunoreactivity in 48 formalin-fixed/paraffin-embedded mantle cell lymphoma tumors was determined by estimating the percentage of positive cells.
  • Of these 48 mantle cell lymphoma patients, 41 were men and seven were women.
  • In benign lymph nodes, the expression of cdc2 and alpha-tubulin was restricted to the germinal centers; mantle zones were negative.
  • In mantle cell lymphoma, Ki67 significantly correlated with all three markers (P<0.05, Spearman), but only Ki67 (>50%) and cdc2 (>25%) significantly correlated with shorter survival (P<0.0006, Spearman).
  • We have validated the prognostic value of cdc2, and confirmed that of Ki67, in a cohort of mantle cell lymphoma patients.
  • Immunohistochemical detection of cdc2 and Ki67 may be a useful and simple method in evaluating the prognosis of mantle cell lymphoma patients.
  • [MeSH-major] Biomarkers, Tumor / analysis. CDC2 Protein Kinase / biosynthesis. Lymphoma, Mantle-Cell / metabolism. Lymphoma, Mantle-Cell / mortality

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  • (PMID = 15933757.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromosomal Proteins, Non-Histone; 0 / Ki-67 Antigen; 0 / Microfilament Proteins; 0 / Tubulin; 0 / centromere protein F; EC 2.7.11.22 / CDC2 Protein Kinase
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86. Bianciotto C, Shields CL, Lally SE, Freire J, Shields JA: CyberKnife radiosurgery for the treatment of intraocular and periocular lymphoma. Arch Ophthalmol; 2010 Dec;128(12):1561-7
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  • [Title] CyberKnife radiosurgery for the treatment of intraocular and periocular lymphoma.
  • OBJECTIVES: To evaluate efficacy, patient tolerance, and adverse effects of CyberKnife radiosurgery for the treatment of intraocular and periocular lymphoma.
  • The tissue location of the lymphoma was orbit (7 eyes), conjunctiva (3 eyes), choroid (2 eyes), and retina (2 eyes).
  • The lymphoma type was classified as extranodal marginal zone B-cell lymphoma in 7 eyes (50%), diffuse large B-cell lymphoma in 3 eyes (21%), follicular lymphoma in 2 eyes (14%), and benign reactive lymphoid hyperplasia in 2 eyes (14%).
  • Radiation-associated adverse effects included mild dry eye in 2 patients and cataract in 1 patient with conjunctival lymphoma.
  • CONCLUSIONS: CyberKnife radiosurgery is a well-tolerated technique for the treatment of intraocular and periocular lymphoma, allowing for local resolution of the lesions.
  • [MeSH-major] Eye Neoplasms / surgery. Lymphoma, Non-Hodgkin / surgery. Pseudolymphoma / surgery. Radiosurgery

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  • (PMID = 21149780.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Witzig TE, Inwards DJ, Habermann TM, Dogan A, Kurtin PJ, Gross JB Jr, Ananthamurthy A, Ristow KM, Garity JA: Treatment of benign orbital pseudolymphomas with the monoclonal anti-CD20 antibody rituximab. Mayo Clin Proc; 2007 Jun;82(6):692-9
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  • [Title] Treatment of benign orbital pseudolymphomas with the monoclonal anti-CD20 antibody rituximab.
  • RESULTS: Ninety-eight patients were evaluated, and the biopsy results revealed malignant non-Hodgkin lymphoma in 72 (73%); the other 26 (27%) had a pseudolymphoma.
  • CONCLUSION: Benign lymphoproliferative tumors are responsive to monoclonal antibody therapy targeted to B lymphocytes.

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  • (PMID = 17550749.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antineoplastic Agents; 4F4X42SYQ6 / Rituximab
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88. Brinkman J, de Nef JJ, Barth PG, Verschuur AC: Burkitt lymphoma in a child with Joubert syndrome. Pediatr Blood Cancer; 2005 Apr;44(4):397-9
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  • [Title] Burkitt lymphoma in a child with Joubert syndrome.
  • Previously known associations between Joubert syndrome and tumors, are benign soft tissue tumors of the tongue and laryngeal lymphangioma.
  • This report describes a 17-year-old boy known with Joubert syndrome, who was diagnosed with Burkitt lymphoma.
  • [MeSH-major] Abnormalities, Multiple. Burkitt Lymphoma. Cerebellar Ataxia. Cerebellum / abnormalities. Muscle Hypotonia. Psychomotor Disorders

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  • [CommentIn] Pediatr Blood Cancer. 2005 Nov;45(6):863-4 [15926161.001]
  • (PMID = 15562502.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Wiernik PH: Serum CA125 and PSA concentrations in patients with lymphoma. Clin Adv Hematol Oncol; 2008 Jul;6(7):527-31
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  • [Title] Serum CA125 and PSA concentrations in patients with lymphoma.
  • Serum CA125 can be elevated in many benign and malignant conditions in which coelomic epithelium is involved.
  • Although lymphoma cells do not secrete CA125, several investigators have reported serum elevations of CA125 in as many as 40% of patients with non-Hodgkin lymphoma (NHL), particularly when peritoneal, pleural, or pericardial effusions are present.
  • A number of investigators have suggested including serum CA125 levels in prognostic indices for lymphoma.
  • PSA elevations have been reported in patients with NHL less frequently than CA125 elevations, but the PSA in such cases appears to be secreted by the lymphoma cells themselves.
  • [MeSH-major] Lymphoma, Non-Hodgkin / blood. Prostate-Specific Antigen / blood. Proteins / analysis

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  • (PMID = 18654120.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / NBR1 protein, human; 0 / Proteins; EC 3.4.21.77 / Prostate-Specific Antigen
  • [Number-of-references] 50
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90. Flangea C, Potencz E, Mihăescu R, Anghel A, Gîju S, Motoc M, Dogaru C: CD30 expression utilization for the accuracy of classical Hodgkin's lymphoma staging. Rom J Morphol Embryol; 2006;47(2):113-7
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  • [Title] CD30 expression utilization for the accuracy of classical Hodgkin's lymphoma staging.
  • INTRODUCTION: The presence of Reed-Sternberg malignant cells is absolutely necessary for Hodgkin's lymphoma diagnostic, but it is not always sufficient because can be observed Reed-Sternberg-like cells in other malignant and benign diseases, too.
  • MATERIAL AND METHODS: Our study was composed from 63 cases histopathological diagnosed with Hodgkin's lymphoma and hospitalized in Hematology Department of County Hospital Timişoara.
  • We consider that using this staining, although less used in Romania, must be done in all Hodgkin's lymphoma and Hodgkin's lymphoma-like cases.

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  • (PMID = 17106517.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD30
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91. von Falck C, Rosenthal H, Gratz KF, Galanski M: Nonossifying fibroma can mimic residual lymphoma in FDG PET: additional value of combined PET/CT. Clin Nucl Med; 2007 Aug;32(8):640-2
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  • [Title] Nonossifying fibroma can mimic residual lymphoma in FDG PET: additional value of combined PET/CT.
  • A 12-year-old girl was diagnosed with Hodgkin's lymphoma and underwent conventional cross-sectional imaging for initial staging.
  • The scan demonstrated focal uptake of FDG in the right distal femur and residual lymphoma was taken into consideration.
  • However, findings in the coregistered CT scan were consistent with nonossfiying fibroma, a common benign skeletal lesion.
  • Combined PET/CT imaging can be helpful to identify benign bone lesions mimicking metastatic or residual disease in F-18 FDG PET as illustrated by this case.
  • [MeSH-major] Femoral Neoplasms / diagnosis. Fibroma / radionuclide imaging. Fluorodeoxyglucose F18. Hodgkin Disease / diagnosis. Lymphoma / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 17667441.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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92. Avenia N, Ragusa M, Cirocchi R, Puxeddu E, Cavaliere A, De Feo P, Sidoni A, Roila F, Sanguinetti A, Puma F: Surgical treatment of primitive thyroid lymphoma. Tumori; 2009 Nov-Dec;95(6):712-9
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  • [Title] Surgical treatment of primitive thyroid lymphoma.
  • AIMS AND BACKGROUND: Primitive thyroid lymphoma, although rare, is becoming more frequent.
  • In fact, it is often the result of pathologic findings on a gland resected for an apparently benign disease.
  • RESULTS: Six cases of thyroid lymphoma were retrospectively reviewed: 4 diffuse large B-cell lymphomas and 2 MALT lymphomas.
  • All patients with stage IE lymphoma who underwent total thyroidectomy had equivalent surgical complications and prognosis.
  • [MeSH-major] Incidental Findings. Lymphoma / diagnosis. Lymphoma / surgery. Thyroid Neoplasms / diagnosis. Thyroid Neoplasms / surgery. Thyroidectomy
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Hashimoto Disease / complications. Humans. Incidence. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / surgery. Lymphoma, Large B-Cell, Diffuse / diagnosis. Lymphoma, Large B-Cell, Diffuse / surgery. Male. Middle Aged. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 20210235.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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93. Rahemtullah A, Harris NL, Dorn ME, Preffer FI, Hasserjian RP: Beyond the lymphocyte predominant cell: CD4+CD8+ T-cells in nodular lymphocyte predominant Hodgkin lymphoma. Leuk Lymphoma; 2008 Oct;49(10):1870-8
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  • [Title] Beyond the lymphocyte predominant cell: CD4+CD8+ T-cells in nodular lymphocyte predominant Hodgkin lymphoma.
  • However, two recent studies describing a CD4+CD8+ (double-positive) T-cell population in nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) suggest that flow cytometry could play a role in the diagnosis of this Hodgkin lymphoma subtype.
  • CD4+CD8+ T-cells have also been identified in the benign entity progressive transformation of germinal centres (PTGC), suggesting a possible relationship between NLPHL and PTGC.

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  • (PMID = 18949610.001).
  • [ISSN] 1029-2403
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD4; 0 / Antigens, CD8
  • [Number-of-references] 49
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94. Ren LQ, Xue LY, Bi R, Liang JM, Lin DM, Ma J, Lü N: [Application of flow cytometric immunophenotypic analysis in the diagnosis of malignant lymphoma]. Zhonghua Xue Ye Xue Za Zhi; 2007 Oct;28(10):671-6
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  • [Title] [Application of flow cytometric immunophenotypic analysis in the diagnosis of malignant lymphoma].
  • OBJECTIVE: To explore the value of flow cytometric immunophenotyping (FCI) in the diagnosis and differentiated diagnosis of lymphoma and explain the immunophenotypic features and differences of malignant lymphoma.
  • METHODS: Seventy four fresh samples of suspicious lymphoma were collected from Nov.
  • For the diagnosis of B and T non-Hodgkin's lymphoma (NHL), thymoma, carcinoma and benign lesions of lymph node, the concordance between FCI data and morphological diagnosis were 93.5%, 100%, 100%, 100% and 81.3%, respectively.
  • CONCLUSION: Multi-parameter FCI analysis can provide important information and help for diagnosis of lymphoma.
  • It is an assistant but necessary approach for the diagnosis and differential diagnosis of lymphoma.
  • [MeSH-major] Flow Cytometry. Immunophenotyping / methods. Lymphoma / diagnosis

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  • (PMID = 18399172.001).
  • [ISSN] 0253-2727
  • [Journal-full-title] Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • [ISO-abbreviation] Zhonghua Xue Ye Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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95. Takabe K, Al-Refaie W, Chin B, Chu PK, Baird SM, Blair SL: Can large B-cell lymphoma mimic cystic lesions of the spleen? Int J Gastrointest Cancer; 2005;35(1):83-8
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  • [Title] Can large B-cell lymphoma mimic cystic lesions of the spleen?
  • On final histological analysis, it was diagnosed to be a large B-cell lymphoma.
  • Despite its rarity, gastroenterologists and surgeons should be aware of large B-cell lymphoma when encountering cystic lesions of the spleen, because the management of benign cystic disease is usually nonsurgical.
  • [MeSH-major] Cysts / diagnosis. Lymphoma, B-Cell / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis. Splenic Diseases / diagnosis. Splenic Neoplasms / diagnosis

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  • (PMID = 15722578.001).
  • [ISSN] 1537-3649
  • [Journal-full-title] International journal of gastrointestinal cancer
  • [ISO-abbreviation] Int J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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96. Farinha P, Masoudi H, Skinnider BF, Shumansky K, Spinelli JJ, Gill K, Klasa R, Voss N, Connors JM, Gascoyne RD: Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL). Blood; 2005 Sep 15;106(6):2169-74
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  • [Title] Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).
  • We studied the role of multiple biomarkers in determining outcome in follicular lymphoma (FL), concentrating in particular on the role of benign macrophages.
  • A multivariate Cox model that included the IPI score, the histologic grade, and the lymphoma-associated macrophage (LAM) score, showed IPI and LAM to be independent predictors of OS (P = .009 and P = .004, respectively).
  • [MeSH-major] Lymphoma, Follicular / diagnosis. Lymphoma, Follicular / mortality. Macrophages / cytology. Predictive Value of Tests


97. Dursun P, Gultekin M, Bozdag G, Usubutun A, Uner A, Celik NY, Yuce K, Ayhan A: Primary cervical lymphoma: report of two cases and review of the literature. Gynecol Oncol; 2005 Sep;98(3):484-9
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  • [Title] Primary cervical lymphoma: report of two cases and review of the literature.
  • BACKGROUND: Primary lymphoma arising from the female genital tract has been rarely encountered.
  • Primary cervical lymphoma is even rarer in gynecologic oncology practice and accounts for approximately only 1% of extranodal lymphomas.
  • In this article, two cases of cervical lymphoma are presented with a review of the available literature.
  • Histopathological evaluation of LEEP material was reported as diffuse large B cell lymphoma.
  • Punch biopsy under colposcopic examination presented no remarkable pathology except for a benign inflammation.
  • Due to discordance between cytology and histology, LEEP was performed under colposcopic examination, which revealed follicular lymphoma grade III.
  • CONCLUSION: Primary cervical lymphoma is a rare disorder.
  • [MeSH-major] Lymphoma / pathology. Uterine Cervical Neoplasms / pathology


98. Yi JH, Kim SJ, Choi JY, Ko YH, Kim BT, Kim WS: 18F-FDG uptake and its clinical relevance in primary gastric lymphoma. Hematol Oncol; 2010 Jun;28(2):57-61
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 18F-FDG uptake and its clinical relevance in primary gastric lymphoma.
  • We studied the clinical relevance of (18)F-fluorodeoxyglucose ((18)F-FDG) uptake in patients with primary gastric lymphoma underwent positron emission tomography (PET)/ computed tomography (CT) scan.
  • Forty-two patients with primary gastric lymphoma were analysed: 32 diffuse large B-cell lymphomas (DLBCL) and 10 extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT lymphomas).
  • All of these gastric lesions were grossly and pathologically benign lesions without evidence of lymphoma cells.
  • In conclusion, PET/CT scan can be used in staging patients with primary gastric lymphoma; however, the residual (18)F-FDG uptake observed during follow-up should be interpreted cautiously and should be combined with endoscopy and multiple biopsies of the stomach.
  • [MeSH-major] Fluorine Radioisotopes. Fluorodeoxyglucose F18. Lymphoma, B-Cell, Marginal Zone / radionuclide imaging. Lymphoma, Large B-Cell, Diffuse / radionuclide imaging. Positron-Emission Tomography. Radiopharmaceuticals. Stomach Neoplasms / radionuclide imaging

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  • [Copyright] (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19593742.001).
  • [ISSN] 1099-1069
  • [Journal-full-title] Hematological oncology
  • [ISO-abbreviation] Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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99. Amorena Muro E, Borda Celaya F, Martínez-Peñuela Virseda JM, Borobio Aguilar E, Oquiñena Legaz S, Jiménez Pérez FJ: [Analysis of the clinical benefits and cost-effectiveness of performing a systematic second-look gastroscopy in benign gastric ulcer]. Gastroenterol Hepatol; 2009 Jan;32(1):2-8
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of the clinical benefits and cost-effectiveness of performing a systematic second-look gastroscopy in benign gastric ulcer].
  • INTRODUCTION: We analyzed the need to routinely perform a second gastroscopy after an initial diagnosis of benign gastric ulcer.
  • RESULTS: There were 178 benign ulcers (79%) and 48 malignant ulcers (21%).
  • Three new cases of MALT lymphoma and three new cases of gastric adenocarcinoma were diagnosed and could be treated with curative intent.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / economics. Adenocarcinoma / pathology. Cost-Benefit Analysis. Diagnosis, Differential. Early Diagnosis. Gastric Mucosa / pathology. Humans. Internship and Residency. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / economics. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / economics. Lymphoma, Non-Hodgkin / pathology. Medical Staff, Hospital. Precancerous Conditions / diagnosis. Precancerous Conditions / economics. Precancerous Conditions / pathology. Predictive Value of Tests. Reproducibility of Results. Retrospective Studies. Sensitivity and Specificity

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  • (PMID = 19174093.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Spain
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100. Guastafierro S, Falcone U, Celentano M, Cappabianca S, Giudice A, Colella G: Primary mantle-cell non-Hodgkin's lymphoma of the tongue. Int J Hematol; 2008 Sep;88(2):206-8
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mantle-cell non-Hodgkin's lymphoma of the tongue.
  • The evaluation of tongue swellings often represents a diagnostic challenge, because of the wide spectrum of benign and malignant possible lesions.
  • Diagnosis of primary Mantle Cell non-Hodgkin's Lymphoma of the tongue was made by histological, immunohistochemical and cytogenetic studies.
  • [MeSH-major] Lymphoma, Mantle-Cell / pathology. Magnetic Resonance Imaging. Tongue / pathology. Tongue Neoplasms / pathology

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  • (PMID = 18629601.001).
  • [ISSN] 0925-5710
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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