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1. Liao CH, Chueh SC, Lai MK, Hsiao PJ, Chen J: Laparoscopic adrenalectomy for potentially malignant adrenal tumors greater than 5 centimeters. J Clin Endocrinol Metab; 2006 Aug;91(8):3080-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Final pathology revealed eight malignant (four adrenocortical carcinomas and four metastatic carcinomas) and 31 benign tumors (14 cortical adenomas, eight pheochromocytomas, six myelolipomas, and three ganglioneuromas).
  • Four patients (two adrenocortical carcinomas, one metastatic hepatoma, and one lymphoma) died 24, 10, 9, and 3 months after surgery, respectively.

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  • [CommentIn] Nat Clin Pract Endocrinol Metab. 2007 Mar;3(3):210-1 [17262068.001]
  • (PMID = 16720665.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. Sousa Ade A, Soares JM, Sá Santos MH, Martins MP, Salles JM: Kikuchi-Fujimoto disease: three case reports. Sao Paulo Med J; 2010 Jul;128(4):232-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It can be histologically confused with lymphoma.
  • The disease is benign and self-limiting and an excisional biopsy of an affected lymph node is necessary for diagnosis.

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  • (PMID = 21120436.001).
  • [ISSN] 1806-9460
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
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3. Redman RS, Katuri V, Tang Y, Dillner A, Mishra B, Mishra L: Orofacial and gastrointestinal hyperplasia and neoplasia in smad4+/- and elf+/-/smad4+/- mutant mice. J Oral Pathol Med; 2005 Jan;34(1):23-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: In addition to polyps and adenocarcinomas of the stomach and duodenum, the smad4+/- mice developed squamous cell carcinomas of the skin, oral mucosa and forestomach, benign neoplasms of connective tissue and lacrimal gland, and a lymphoma.

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  • (PMID = 15610403.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01DK56111; United States / NIDDK NIH HHS / DK / R01DK58637
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Smad4 Protein; 0 / Trans-Activators
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4. Bandyopadhyay A, Das TK, Raha K, Hati GC, Mitra PK, Dasgupta A: A study of fine needle aspiration cytology of salivary gland lesions with histopathological corroboration. J Indian Med Assoc; 2005 Jun;103(6):312-4, 316
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A major diagnostic categories were inflammatory lesions (n = 7 5), cystic lesions (n = 9), benign tumours (n = 81), malignant neoplasms (n = 1 8) and normal acinar pattern (n = 2).
  • Malignant tumours included muco-epidermoid carcinoma (n = 5), adenoid cystic carcinoma (n = 3), acinic cell carcinoma (n = 2), adenocarcinoma (n= 2), squamous cell carcinoma (n = 1), undifferentiated carcinoma (n= 4) and malignant lymphoma (n = 1).
  • Histopathological correlation was possible in 40% of benign and 80% of malignant neoplasms.

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  • (PMID = 16225156.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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5. Blumer SL, Scalcione LR, Ring BN, Johnson R, Motroni B, Katz DS, Yung EY: Cutaneous and subcutaneous imaging on FDG-PET: benign and malignant findings. Clin Nucl Med; 2009 Oct;34(10):675-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous and subcutaneous imaging on FDG-PET: benign and malignant findings.
  • However, false-positive interpretations may occur from benign subcutaneous and cutaneous etiologies.
  • Additionally, malignant cutaneous and subcutaneous malignant lesions may also demonstrate substantial F-18 FDG uptake on PET scans, including lymphoma, skin metastases, and melanoma.
  • The purpose of this atlas article is to demonstrate and review key features of various cutaneous and subcutaneous lesions, both benign and malignant, which can result in hypermetabolism on FDG-PET or PET-CT scans.

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  • (PMID = 19893399.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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6. Nakase K, Yamamoto K, Hiasa A, Tawara I, Yamaguchi M, Shiku H: Contrast-enhanced ultrasound examination of lymph nodes in different types of lymphoma. Cancer Detect Prev; 2006;30(2):188-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Contrast-enhanced ultrasound examination of lymph nodes in different types of lymphoma.
  • BACKGROUND: Since the tumor growth depends on the formation of feeding vessels, color/power Doppler ultrasonography (US) has been used to evaluate the vascular flow images of lymph nodes (LNs) in order to differentiate benign LNs from malignant LNs or lymphoma from metastatic carcinoma.
  • METHODS: We performed color/power Doppler ultrasonography (US) using Levovist (LV) to evaluate the vascular patterns in the LNs of 10 patients with different types of lymphoma.
  • The vascular pattern of the LNs was of the central type in all seven B-cell lymphoma patients and one of two T-cell lymphoma patients and of the peripheral type in the remaining T-cell lymphoma patient.
  • The avascular type pattern was observed in one Hodgkin lymphoma patient even with LV.
  • DISCUSSION: Typical vascular patterns might be associated with certain subtypes of lymphoma, and LV appears to improve the diagnostic value of Doppler US.
  • [MeSH-major] Lymph Nodes / ultrasonography. Lymphatic Vessels / ultrasonography. Lymphoma / ultrasonography

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  • (PMID = 16632242.001).
  • [ISSN] 0361-090X
  • [Journal-full-title] Cancer detection and prevention
  • [ISO-abbreviation] Cancer Detect. Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Polysaccharides; 127279-08-7 / SHU 508
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7. Trimeche M, Korbi S, Ziadi S, Amara K, Boniver J, de Leval L: [Molecular characterization of Epstein-Barr virus associated with classical Hodgkin's lymphoma in Tunisia: prevalence of the LMP1 oncogene deletions and A and B viruses strains]. Ann Biol Clin (Paris); 2005 Mar-Apr;63(2):193-9
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  • [Title] [Molecular characterization of Epstein-Barr virus associated with classical Hodgkin's lymphoma in Tunisia: prevalence of the LMP1 oncogene deletions and A and B viruses strains].
  • [Transliterated title] Caractérisation moléculaire du virus d'Epstein-Barr associé au lymphome de Hodgkin classique en Tunisie: prévalence des délétions de l'oncogène LMP1 et des souches virales A et B.
  • Epstein-Barr virus (EBV) is detected in Hodgkin's lymphoma (HL) at variable frequencies, depending on various factors including the geographic location.
  • The aim of the current work was to define the genotypic features of EBV in a series of EBV-positive HL in this area, in comparison to those of EBV found in association with benign lymphoadenopathies.

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  • (PMID = 15771977.001).
  • [ISSN] 0003-3898
  • [Journal-full-title] Annales de biologie clinique
  • [ISO-abbreviation] Ann. Biol. Clin. (Paris)
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / EBV-associated membrane antigen, Epstein-Barr virus; 0 / Oncogene Proteins, Viral; 0 / Viral Matrix Proteins
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8. Vahid B, Leone FT: The solitary pulmonary nodule: not always bronchogenic carcinoma. Prim Care Respir J; 2006 Aug;15(4):256-8
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  • Benign causes include infectious granulomas and hamartomas, and less commonly, rheumatoid nodules, intrapulmonary lymph nodes and sarcoidosis.
  • Primary pulmonary non-Hodgkins lymphoma is a rare disease, constituting 0.4% of all lymphomas.
  • We present a case of primary pulmonary non-Hodgkins lymphoma which presented as a SLN in an 87-year old lady with a smoking history of 50 pack years.
  • [MeSH-major] Lung Neoplasms / complications. Lymphoma, B-Cell / complications. Lymphoma, Non-Hodgkin / complications. Solitary Pulmonary Nodule / etiology

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  • (PMID = 16854629.001).
  • [ISSN] 1471-4418
  • [Journal-full-title] Primary care respiratory journal : journal of the General Practice Airways Group
  • [ISO-abbreviation] Prim Care Respir J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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9. Okada T, Mibayashi H, Hasatani K, Hayashi Y, Tsuji S, Kaneko Y, Yoshimitsu M, Tani T, Zen Y, Yamagishi M: Pseudolymphoma of the liver associated with primary biliary cirrhosis: a case report and review of literature. World J Gastroenterol; 2009 Sep 28;15(36):4587-92
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  • Although we could find only one case of transformation of hepatic pseudolymphoma into lymphoma in the liver, the exact nature of development from benign pseudolymphoma to malignant lymphoma is still not fully understood and cases of hepatic lymphoma need to be followed carefully.

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  • (PMID = 19777620.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD3
  • [Number-of-references] 51
  • [Other-IDs] NLM/ PMC2752006
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10. Chatelain D, Mokrani N, Fléjou JF: [Anal and anal margin tumors]. Ann Pathol; 2007 Dec;27(6):459-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign tumors mainly consist of condylomas, cloacogenic polyps and fibro-epithelial polyps.
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Endocrine Gland Neoplasms / epidemiology. Endocrine Gland Neoplasms / pathology. France / epidemiology. Humans. Incidence. Leiomyosarcoma / pathology. Lymphoma / pathology. Melanoma / epidemiology. Melanoma / pathology. Papilloma / pathology. Sarcoma, Kaposi / pathology

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  • (PMID = 18554556.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 110
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11. Kaspareit J, Friderichs-Gromoll S, Buse E, Habermann G: Spontaneous neoplasms observed in cynomolgus monkeys (Macaca fascicularis) during a 15-year period. Exp Toxicol Pathol; 2007 Nov;59(3-4):163-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The great majority of neoplasms was benign (23 benign neoplasms versus 10 malignant tumors).
  • Four animals revealed malignant lymphoma infiltrating multiple organs.

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  • (PMID = 17869495.001).
  • [ISSN] 0940-2993
  • [Journal-full-title] Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie
  • [ISO-abbreviation] Exp. Toxicol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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12. Plaza JA, Morrison C, Magro CM: Assessment of TCR-beta clonality in a diverse group of cutaneous T-Cell infiltrates. J Cutan Pathol; 2008 Apr;35(4):358-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • While some unequivocally benign infiltrates are easy to distinguish from cutaneous T-cell lymphoma (CTCL), drug-associated lymphomatoid hypersensitivity reaction and cutaneous lesions of collagen vascular disease can show cytologic atypia, clonality and an immunophenotypic profile that closely simulates CTCL and cause diagnostics difficulties.
  • Similar immunophenotypic and molecular abnormalities to those of malignant lymphoma can also be observed in pityriasis lichenoides chronica (PLC), large plaque parapsoriasis (LPP), pigmented purpuric dermatosis (PPD) and atypical lymphocytic lobular panniculitis leading one to consider these entities as forms of cutaneous lymphoid dyscrasia.
  • [MeSH-major] Gene Rearrangement, beta-Chain T-Cell Antigen Receptor / genetics. Genes, T-Cell Receptor / genetics. Leukemic Infiltration. Lymphoma, T-Cell, Cutaneous / genetics

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  • (PMID = 17976210.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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13. Dursun P, Gultekin M, Bozdag G, Usubutun A, Uner A, Celik NY, Yuce K, Ayhan A: Primary cervical lymphoma: report of two cases and review of the literature. Gynecol Oncol; 2005 Sep;98(3):484-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cervical lymphoma: report of two cases and review of the literature.
  • BACKGROUND: Primary lymphoma arising from the female genital tract has been rarely encountered.
  • Primary cervical lymphoma is even rarer in gynecologic oncology practice and accounts for approximately only 1% of extranodal lymphomas.
  • In this article, two cases of cervical lymphoma are presented with a review of the available literature.
  • Histopathological evaluation of LEEP material was reported as diffuse large B cell lymphoma.
  • Punch biopsy under colposcopic examination presented no remarkable pathology except for a benign inflammation.
  • Due to discordance between cytology and histology, LEEP was performed under colposcopic examination, which revealed follicular lymphoma grade III.
  • CONCLUSION: Primary cervical lymphoma is a rare disorder.
  • [MeSH-major] Lymphoma / pathology. Uterine Cervical Neoplasms / pathology


14. Daum S, Thiel E, Zeitz M: Is intestinal diffuse large b cell lymphoma a relatively benign disease? Leuk Res; 2007 Mar;31(3):287-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is intestinal diffuse large b cell lymphoma a relatively benign disease?
  • [MeSH-major] Intestinal Neoplasms / diagnosis. Lymphoma, B-Cell / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis

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  • [CommentOn] Leuk Res. 2007 Mar;31(3):359-64 [16930692.001]
  • (PMID = 17010434.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Publication-type] Comment; Editorial; Review
  • [Publication-country] England
  • [Number-of-references] 19
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15. Patel T, Given-Wilson RM, Thomas V: The clinical importance of axillary lymphadenopathy detected on screening mammography: revisited. Clin Radiol; 2005 Jan;60(1):64-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Those with a definite diagnosis were referred for appropriate management and those with benign reactive cytology on FNAC reviewed at 6 weeks with subsequent referral for excision of persisting abnormal nodes.
  • RESULTS: The ultimate diagnosis was benign in 45 cases: 26 benign reactive changes, 11 arthritides, five with dermatological and viral conditions and three with tuberculosis.
  • Malignancy was diagnosed in 13 cases: four with metastatic breast carcinoma and nine with lymphoma/leukaemia.
  • Of the 22 patients with benign reactive cytology, one had significant pathology on excision biopsy: tuberculosis.


16. Xu XL, Li B, Sun XL, Li LQ, Ren RJ, Gao F, Jonas JB: Eyelid neoplasms in the Beijing Tongren Eye Centre between 1997 and 2006. Ophthalmic Surg Lasers Imaging; 2008 Sep-Oct;39(5):367-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Of the 2,639 eyelid specimens, 2,276 (86.2%) were benign and 363 (13.8%) were malignant.
  • The most common benign lesions were inflammatory lesions, melanocytic nevi, papillomas, dermoid and epidermoid cysts, and epithelial cysts.
  • The mean age at diagnosis was 41 years for benign lesions and 60 years for malignant tumors.
  • There was no significant gender predilection among the five major non-benign eyelid tumors.
  • CONCLUSION: At the BeijingTongren Eye Centre between 1997 and 2006, the predominant non-benign eyelid tumors were basal cell carcinoma and sebaceous gland carcinoma, followed by lymphoma.
  • The non-benign lesions occurred predominantly in elderly patients who were 60 years of age and older.

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  • (PMID = 18831417.001).
  • [ISSN] 1542-8877
  • [Journal-full-title] Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
  • [ISO-abbreviation] Ophthalmic Surg Lasers Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Li Y, Zhong DR, Cui QC: [Advances in primary thyroid lymphoma]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2006 Oct;28(5):724-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Advances in primary thyroid lymphoma].
  • It is really necessary to improve the ability to differentiate between benign and malignant PTLs along with the introduction of some new molecular biology methods.
  • Customized therapy of PTLs becomes possible with the further advances in lymphoma's pathological classification, clinical stages, and international prognosis index standard.
  • [MeSH-major] Lymphoma. Thyroid Neoplasms

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  • (PMID = 17121242.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 20
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18. Auerbach A, Fanburg-Smith JC, Wang G, Rushing EJ: Focal myositis: a clinicopathologic study of 115 cases of an intramuscular mass-like reactive process. Am J Surg Pathol; 2009 Jul;33(7):1016-24
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  • Clinical diagnostic considerations ranged from benign entities such as rhabdomyoma, intramuscular lipoma, fibromatosis, myositis ossificans, proliferative myositis, inflammatory myofibroblastic tumor, and inflammatory myopathy to malignant entities such as rhabdomyosarcoma, leiomyosarcoma, liposarcoma, and lymphoma.

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  • (PMID = 19363438.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin Heavy Chains
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19. Huang BY, Castillo M: Nonadenomatous tumors of the pituitary and sella turcica. Top Magn Reson Imaging; 2005 Jul;16(4):289-99
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  • While pituitary adenomas make up over 90% of all sellar masses, there are a number of less known tumors, both malignant and benign, which may arise within the sella turcica.
  • [MeSH-major] Craniopharyngioma / diagnosis. Ganglioneuroma / diagnosis. Granular Cell Tumor / diagnosis. Lymphoma / diagnosis. Meningioma / diagnosis. Pituitary Neoplasms / diagnosis. Sella Turcica / pathology

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  • (PMID = 16785844.001).
  • [ISSN] 0899-3459
  • [Journal-full-title] Topics in magnetic resonance imaging : TMRI
  • [ISO-abbreviation] Top Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 80
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20. Wang Z, Guo Z, Li J, Li XD, Sang HX: Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection. Orthop Surg; 2010 Feb;2(1):19-26
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  • METHODS: Twenty-five patients who underwent Malawer I type resection and reconstruction of the proximal humerus for treatment of malignant or invasive benign tumors from August 1999 to August 2005 were evaluated.
  • RESULTS: The study group consisted of 10 male and 15 female patients, among which there were 20 malignant and 5 benign tumors.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Lymphoma / mortality. Lymphoma / pathology. Lymphoma / surgery. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Postoperative Complications / epidemiology. Recovery of Function. Retrospective Studies. Treatment Outcome. Young Adult

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  • [Copyright] © 2010 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.
  • (PMID = 22009903.001).
  • [ISSN] 1757-7861
  • [Journal-full-title] Orthopaedic surgery
  • [ISO-abbreviation] Orthop Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Australia
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21. Arora AJ, Mohapatra T, Shaikh S, Arora RA: Increased renal corticomedullary FDG activity in a patient of NHL-malignant or benign? Indian J Nucl Med; 2010 Oct;25(4):178
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  • [Title] Increased renal corticomedullary FDG activity in a patient of NHL-malignant or benign?
  • Authors describe diagnostic dilemma of differentiating pyelonephritis with lymphomatous involvement of kidney in a known case of lymphoma.

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  • [Cites] Clin Nucl Med. 2009 Oct;34(10):722-4 [19893414.001]
  • [Cites] Radiographics. 1997 Jul-Aug;17(4):851-66; discussion 867-8 [9225387.001]
  • [Cites] South Med J. 2010 Jul;103(7):642-9 [20531045.001]
  • (PMID = 21712917.001).
  • [ISSN] 0974-0244
  • [Journal-full-title] Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
  • [ISO-abbreviation] Indian J Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3109829
  • [Keywords] NOTNLM ; FDG PET-CT / lymphoma / pyelonephritis
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22. D'Onofrio M, Rozzanigo U, Masinielli BM, Caffarri S, Zogno A, Malagò R, Procacci C: Hypoechoic focal liver lesions: characterization with contrast enhanced ultrasonography. J Clin Ultrasound; 2005 May;33(4):164-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: There were 37/88 benign lesions demonstrated: 17 cavernous hemangiomas, 3 capillary hemangiomas, 11 focal nodular hyperplasias (FNH), 3 focal areas of sparing in hepatic steatosis, 2 adenomas, and 1 intrahepatic necrotic area.
  • Malignant lesions demonstrated included 51/88: 27 hepatocellular carcinomas (HCC) in cirrhosis, 11 metastatic carcinomas, 10 metastatic endocrine tumors, 2 cholangiocellular carcinomas (CCC) and 1 non-Hodgkin's lymphoma (NHL).
  • CEUS characterized 30/37 (81%) benign lesions and 45/51 (88%) malignant lesions.
  • On the basis of the results obtained during the sinusoidal contrast enhanced phase of CEUS, diagnosis of benignancy was possible in 35/37 (95%) of benign liver lesions and diagnosis of malignancy in 49/51 (96%) of malignant liver lesions.
  • CONCLUSIONS: CEUS distinguished malignant from benign hypoechoic liver lesions with an accuracy of 95%.

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  • [Copyright] Copyright 2005 Wiley Periodicals, Inc.
  • (PMID = 15856516.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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23. Machida K, Urano K, Yoshimura M, Tsutsumi H, Nomura T, Usui T: Carcinogenic comparative study on rasH2 mice produced by two breeding facilities. J Toxicol Sci; 2008 Oct;33(4):493-501
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  • In the pathological examination, only benign tumors of lungs, spleen, forestomach and skin were observed in a few mice in the vehicle group of both facilities.
  • The incidences of malignant lymphoma in CLEA Japan mice and Taconic mice were 86.7% and 93.3%, respectively, and no significant difference was observed (Fisher's exact probability test).

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  • (PMID = 18827450.001).
  • [ISSN] 1880-3989
  • [Journal-full-title] The Journal of toxicological sciences
  • [ISO-abbreviation] J Toxicol Sci
  • [Language] eng
  • [Publication-type] Comparative Study; Letter
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Carcinogens; 684-93-5 / Methylnitrosourea
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24. Haferkamp S, Tran SL, Becker TM, Scurr LL, Kefford RF, Rizos H: The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence. Aging (Albany NY); 2009 Jun;1(6):542-56
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  • Oncogene-induced senescence acts as a barrier against tumour formation and has been implicated as the mechanism preventing the transformation of benign melanocytic lesions that frequently harbour oncogenic B-RAF or N-RAS mutations.


25. Hoffmeier A, Schmid C, Deiters S, Drees G, Rothenburger M, Tjan TD, Schmidt C, Löher A, Maintz D, Spieker T, Mesters RM, Scheld HH: Neoplastic heart disease -- the Muenster experience with 108 patients. Thorac Cardiovasc Surg; 2005 Feb;53(1):1-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common tumour entity is benign cardiac myxoma.
  • All patients underwent radical surgical resection, except for 2 patients who had malignant lymphoma of the heart.
  • RESULTS: Histological findings included 78 myxomas (72.2 %), and 6 other benign cardiac tumours in 5.6 % of the patients.
  • Mean overall survival was 12.7 years for myxoma patients and 5.6 years for patients with other benign heart tumours.

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  • (PMID = 15692911.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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26. Dar NR, Shaheen, Mustafvi SA, Raza N: Cutaneous pseudolymphoma due to topical application of 4% hydroquinone cream for melasma. J Coll Physicians Surg Pak; 2005 Aug;15(8):496-7
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  • Cutaneous pseudolymphoma is an aggregate of mature or abnormal looking lymphocytes in the dermis, which clinically and /or histologically simulates lymphoma but has a benign course and outcome.

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  • (PMID = 16202363.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Hydroquinones; 123-31-9 / hydroquinone
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27. Silverman SG, Mortele KJ, Tuncali K, Jinzaki M, Cibas ES: Hyperattenuating renal masses: etiologies, pathogenesis, and imaging evaluation. Radiographics; 2007 Jul-Aug;27(4):1131-43
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  • Most hyperattenuating renal masses are benign hemorrhagic or proteinaceous cysts.
  • However, solid enhancing hyperattenuating renal masses may have malignant as well as benign causes.
  • Possible malignant causes include renal cell carcinoma and lymphoma; benign causes include angiomyolipoma with minimal fat.
  • CT may be useful for diagnosing benign hyperattenuating renal cysts, hematomas, and vascular anomalies that appear masslike.
  • However, some solid, enhancing, hyperattenuating masses cannot be diagnosed confidently with CT alone: Small (< or = 3-cm-diameter), homogeneously enhancing, hyperattenuating renal masses depicted on CT images may be either benign angiomyolipomas with minimal fat or renal cell carcinomas.

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  • [Copyright] RSNA, 2007
  • (PMID = 17620471.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
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28. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T: [Incidence of benign and malignant lesions of eyelid and conjunctival tumors]. Nippon Ganka Gakkai Zasshi; 2005 Sep;109(9):573-9
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  • [Title] [Incidence of benign and malignant lesions of eyelid and conjunctival tumors].
  • PURPOSE: To examine the incidence of benign and malignant eyelid lesions and conjunctival tumors.
  • The incidence of benign or malignant lesions, the pathological classification, age, sex, and clinical diagnostic accuracy were all investigated.
  • RESULTS: Sixty-four (73%) of the tumors were found to be benign eyelid tumors.
  • The common benign eyelid tumors were 14 nevocellular nevi, 9 seborrheic keratosis, 7 epidermoid cysts, and 6 papillomas.
  • Thirty-four (79%) conjunctival tumors were benign, and the common benign conjunctival tumors were 9 nevocellular nevi and 7 papillomas.
  • The mean ages of malignant eyelid and conjunctival tumor patients were significantly older than those of benign tumor patients.
  • CONCLUSIONS: Approximately 70 approximately 80% of all eyelid and conjunctival tumors are benign.
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Female. Humans. Incidence. Lymphoma / epidemiology. Lymphoma / pathology. Male. Middle Aged. Retrospective Studies

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  • (PMID = 16218435.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 27
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29. Eroğlu A, Sari A: Expression of c-kit proto-oncogene product in breast cancer tissues. Med Oncol; 2007;24(2):169-74
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  • BACKGROUND: The published results on expression of c-kit in benign and malignant breast tissues vary.
  • MATERIALS AND METHODS: The immunohistochemical expression of c-kit proto-oncogene product in 52 invasive breast cancer tissues and 16 benign breast tumor (fibroadenoma) tissues was studied using anti-c-kit proto-oncogene product antibody.

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  • (PMID = 17848740.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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30. Gorai S, Numata T, Kawada S, Nakano M, Tamaru J, Kobayashi T: Malignant lymphoma arising from heterotopic Warthin's tumor in the neck: case report and review of the literature. Tohoku J Exp Med; 2007 Jun;212(2):199-205
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  • [Title] Malignant lymphoma arising from heterotopic Warthin's tumor in the neck: case report and review of the literature.
  • Warthin's tumor (WT), so-called adenolymphoma, is a benign salivary gland tumor with both epithelial and lymphoid histological characteristics, so the histogenesis remains unclear.
  • Here we present a rare case of malignant lymphoma arising from heterotopic (ectopic) WT.
  • The histological diagnosis was malignant lymphoma, diffuse large B-cell type, arising from heterotopic WT.
  • Postoperative staging examination including chest radiography, bone scan, and computed tomography of the abdomen and pelvis revealed no evidence of dissemination of malignant lymphoma.
  • Only 16 cases of malignant transformation arising from WT have been reported, including only three cases of non-Hodgkin lymphoma apparently arising from heterotopic WT.
  • [MeSH-major] Adenolymphoma / pathology. Lymphoma, Large B-Cell, Diffuse / etiology. Neck / pathology

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  • (PMID = 17548964.001).
  • [ISSN] 0040-8727
  • [Journal-full-title] The Tohoku journal of experimental medicine
  • [ISO-abbreviation] Tohoku J. Exp. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD79; 0 / B-Cell-Specific Activator Protein; 0 / PAX5 protein, human
  • [Number-of-references] 28
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31. Winter LK, Spiegel JH, King T: Dermatopathic lymphadenitis of the head and neck. J Cutan Pathol; 2007 Feb;34(2):195-7
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  • While considered a benign histopathologic finding, differentiation of this disorder from mycosis fungoides or lymphoma can be difficult.
  • [MeSH-minor] Adenoma, Pleomorphic / complications. Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Head / pathology. Head and Neck Neoplasms / diagnosis. Humans. Lymphoma / diagnosis. Mycosis Fungoides / diagnosis. Neck / pathology. Parotid Gland / pathology. Parotid Gland / surgery. Parotid Neoplasms / complications. Parotid Neoplasms / pathology. Parotid Neoplasms / surgery

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  • (PMID = 17244033.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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32. Pellegrino M, Vadrucci S, Tinelli A: [Angiomyofibroblastoma of the vulva: a rare but distinct entity. Case report and literature review]. Pathologica; 2007 Dec;99(6):438-9
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  • Angiomyofibroblastoma is a benign vulvar tumour involving soft tissue that is characterized by alternating hypocellular and hypercellular areas of spindle stromal cells, admixed and aggregated around blood vessels.
  • It is important to recognize this entity as it shows benign behaviour with respect to other mesenchymal tumours of the vagina, which have a more aggressive behaviour.
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor. Breast Neoplasms / drug therapy. Breast Neoplasms / surgery. Combined Modality Therapy. Female. Humans. Lymphoma, Large B-Cell, Diffuse / drug therapy. Lymphoma, Large B-Cell, Diffuse / surgery. Neoplasm Proteins / analysis. Receptors, Estrogen / analysis

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  • (PMID = 18416337.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Receptors, Estrogen
  • [Number-of-references] 7
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33. van Besien K, Schouten H: Follicular lymphoma: a historical overview. Leuk Lymphoma; 2007 Feb;48(2):232-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Follicular lymphoma: a historical overview.
  • Lymphoma was first described in 1862 and follicular lymphoma in 1925.
  • Initially considered a benign disorder, and named Brill - Symmers disease after the authors of the original papers, it was rapidly recognized as a malignancy with a variable but often indolent course.
  • Despite discussion about its cell of origin, and in contrast to many other lymphoma subtypes, follicular lymphoma could always be accurately recognized and diagnosed using light microscopy morphological features.
  • B-cell origin was demonstrated in the 1970s and the important role of t(14;18) and bcl-2 gene rearrangement in the pathogenesis of follicular lymphoma was established shortly thereafter.
  • The etiology of follicular lymphoma, the reason for marked geographic variation in its incidence, the role of alternative molecular pathways in its pathogenesis, and the cause for its variable clinical behavior all remain unknown.
  • Several observations suggest an important role for the normal immune response in regulating the clinical behavior of follicular lymphoma.
  • From the earliest descriptions, radiation therapy was shown to be very effective in follicular lymphoma, but not curative.
  • Targeted therapies, particularly rituximab have revolutionized the treatment of follicular lymphoma.
  • For the first time consistent improvements in survival of follicular lymphoma are reported.
  • [MeSH-major] Lymphoma, Follicular / history

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  • (PMID = 17325883.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] England
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34. Sanchez R, Ladino-Torres MF, Bernat JA, Joe A, DiPietro MA: Breast fibroadenomas in the pediatric population: common and uncommon sonographic findings. Pediatr Radiol; 2010 Oct;40(10):1681-9
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  • Forty-three children had a total of 49 pathologically proven breast masses with the diagnoses of fibroadenoma (44), hamartoma (1), non-Hodgkin lymphoma (1), tubular adenoma (1), pseudoangiomatous stromal hyperplasia (1) and lactation changes (1).
  • RESULTS: The vast majority of solid breast masses in girls are histologically benign.

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  • (PMID = 20449731.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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35. Nathoo N, Ugokwe K, Chang AS, Li L, Ross J, Suh JH, Vogelbaum MA, Barnett GH: The role of 111indium-octreotide brain scintigraphy in the diagnosis of cranial, dural-based meningiomas. J Neurooncol; 2007 Jan;81(2):167-74
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  • OBS provided false positive data in 3 patients (metastasis, chronic inflammation, lymphoma).
  • CONCLUSION: OBS may increase the diagnostic specificity of conventional MRI when differentiating meningioma from other dural-based pathologies, while the addition of FDG-PET differentiates benign from malignant lesions.

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  • (PMID = 16850106.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indium Radioisotopes; 0 / Radiopharmaceuticals; 0 / Receptors, Somatostatin; 0 / indium-111-octreotide; 0Z5B2CJX4D / Fluorodeoxyglucose F18; RWM8CCW8GP / Octreotide
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36. Kondi-Pafiti A, Grapsa D, Kairi-Vassilatou E, Kontogianni-Katsarou K, Koliopoulos C, Botsis D: Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature. Eur J Gynaecol Oncol; 2006;27(1):73-7
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  • METHODS: Ten cases of mesenchymal tumors of the uterine corpus, massively infiltrated by hematopoioetic cells, or composed of other benign heterologous elements (adipose tissue in the present cases) were retrieved from the archival files of our laboratory and studied histopathologically.
  • In the presence of massive lymphocytic infiltration of a leiomyoma the clonality of the infiltrate may aid in differentiating it from a malignant lymphoma.

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  • (PMID = 16550975.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 37
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37. Morgan JL, Khan HN, Lambertz MM: Oesophageal stenting in a district general hospital. Surgeon; 2009 Aug;7(4):203-5
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  • Other rarer causes were benign stricture of the oesophagus, lung carcinoma, non-Hodgkin's lymphoma and salivary gland tumour.

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  • (PMID = 19736885.001).
  • [ISSN] 1479-666X
  • [Journal-full-title] The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
  • [ISO-abbreviation] Surgeon
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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38. Panizzon RG: [Dermatologic radiotherapy]. Hautarzt; 2007 Aug;58(8):701-10, quiz 711
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  • The most common benign lesions where radiotherapy may be indicated are eczemas, psoriasis, and keloids, but its use should be carefully weighed in these settings.
  • [MeSH-minor] Eczema / radiotherapy. Humans. Keloid / radiotherapy. Lymphoma, B-Cell / radiotherapy. Lymphoma, T-Cell, Cutaneous / radiotherapy. Palliative Care. Psoriasis / radiotherapy. Radiotherapy Dosage. Sarcoma, Kaposi / radiotherapy

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  • (PMID = 17639284.001).
  • [ISSN] 0017-8470
  • [Journal-full-title] Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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39. Kinns J, Mai W: Association between malignancy and sonographic heterogeneity in canine and feline abdominal lymph nodes. Vet Radiol Ultrasound; 2007 Nov-Dec;48(6):565-9
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  • Certain sonographic features can be used to suggest whether lymphadenopathy is more likely benign or malignant.
  • Twenty-three canine and 18 feline patients with ultrasonographically heterogeneous abdominal nodes were evaluated for presence of benign or malignant lymphadenopathy.
  • [MeSH-major] Cat Diseases / ultrasonography. Dog Diseases / ultrasonography. Lymph Nodes / ultrasonography. Lymphoma / veterinary

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  • (PMID = 18018731.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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40. Oh HR, Lee MJ, Park G, Moon DS, Park YJ, Jang SJ: [A case of lambda-expressing pulmonary MALT lymphoma with dual clonal rearrangements of kappa and lambda immunoglobulin light chain gene]. Korean J Lab Med; 2009 Jun;29(3):256-61
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  • [Title] [A case of lambda-expressing pulmonary MALT lymphoma with dual clonal rearrangements of kappa and lambda immunoglobulin light chain gene].
  • However, the findings of histopathology and immunohistochemistry were not sufficient to decide whether the lesion was benign or malignant, because of the presence of crush artifacts in the biopsy specimens.
  • Based on the clinical, pathologic, and molecular findings, this case was diagnosed as pulmonary MALT lymphoma.
  • We report the first case in Korea of lambda-expressing MALT lymphoma that is shown to have dual clonal rearrangements of kappa and lambda immunoglobulin light chain gene by multiplex PCR.
  • [MeSH-major] Gene Rearrangement, B-Lymphocyte, Light Chain. Immunoglobulin kappa-Chains / genetics. Immunoglobulin lambda-Chains / genetics. Lymphoma, B-Cell, Marginal Zone / diagnosis

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  • (PMID = 19571625.001).
  • [ISSN] 1598-6535
  • [Journal-full-title] The Korean journal of laboratory medicine
  • [ISO-abbreviation] Korean J Lab Med
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Immunoglobulin kappa-Chains; 0 / Immunoglobulin lambda-Chains
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41. Shome D, Esmaeli B: Targeted monoclonal antibody therapy and radioimmunotherapy for lymphoproliferative disorders of the ocular adnexa. Curr Opin Ophthalmol; 2008 Sep;19(5):414-21
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  • PURPOSE OF REVIEW: The goal of this review is to update ophthalmologists and orbital and adnexal specialists with the emerging role of targeted monoclonal antibody therapy and radioimmunotherapy for orbital and adnexal non-Hodgkin's lymphoma and other lymphoproliferative disorders of the orbit.
  • RECENT FINDINGS: Rituximab as monotherapy for indolent lymphoma of the orbit and conjunctiva may be associated with good initial response, but the risk of distant relapse is about 50%.
  • Radioimmunotherapy using targeted monoclonal antibodies with radioactive conjugates is also associated with a more durable response rate than monotherapy with rituximab alone and may be an alternative for treatment of ocular adnexal lymphoma.
  • Rituximab monotherapy may be considered as an alternative to systemic steroids for treatment of orbital benign lymphoid hyperplasia.
  • SUMMARY: Targeted monoclonal antibody therapy is an intriguing new modality for treatment of orbital, eyelid, or conjunctival lymphoma and can be used in combination with radioimmunotherapy or standard chemotherapy for a more durable response.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Conjunctival Neoplasms / therapy. Eyelid Neoplasms / therapy. Lymphoma, Non-Hodgkin / therapy. Orbital Neoplasms / therapy. Radioimmunotherapy

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  • (PMID = 18772675.001).
  • [ISSN] 1531-7021
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 4F4X42SYQ6 / Rituximab
  • [Number-of-references] 44
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42. Abdelwahab IF, Hoch B, Hermann G, Bianchi S, Klein MJ, Springfield DS: Primary periosteal lymphoma--rare and unusual. Skeletal Radiol; 2007 Apr;36(4):335-9
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  • [Title] Primary periosteal lymphoma--rare and unusual.
  • We describe a primary periosteal lymphoma that involved only the periosteum without affecting the adjacent medulla or the regional lymph nodes.
  • This unusual presentation simulates the imaging appearance of surface lesions of bone, namely benign and malignant tumors, and departs from the typical appearance of primary lymphoma of bone.
  • Therefore, this rare type of lymphoma should be considered in the differential diagnosis of surface bone lesions.
  • [MeSH-major] Bone Neoplasms / diagnosis. Femur / pathology. Lymphoma, Large B-Cell, Diffuse / diagnosis. Periosteum / pathology

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  • (PMID = 16534637.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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43. Tamas EF, Epstein JI: Detection of residual tumor cells in bladder biopsy specimens: pitfalls in the interpretation of cytokeratin stains. Am J Surg Pathol; 2007 Mar;31(3):390-7
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  • Immunohistochemistry for a panel of antibodies [AE1/AE3, CAM 5.2, high molecular weight cytokeratin, smooth muscle actin (SMA), desmin, and anaplastic lymphoma kinase (ALK)] was performed on 29 cases of bladder biopsies with prior biopsy site changes.
  • Four patients had prior benign bladder diagnoses: cystitis cystica et glandularis; polypoid cystitis; follicular cystitis; and neurogenic bladder with benign prostate hyperplasia.

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  • (PMID = 17325480.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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44. Jakowski JD, Mayerson J, Wakely PE Jr: Fine-needle aspiration biopsy of the distal extremities: a study of 141 cases. Am J Clin Pathol; 2010 Feb;133(2):224-31
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  • Specific benign or malignant diagnoses were achievable in 71.6% of cases, whereas the remaining cases were given a descriptive diagnosis (26.2%) or, infrequently, a "suspicious for" diagnosis (2.1%).
  • Overall sensitivity and specificity for distinguishing a benign from malignant entity from all 4 sites were 100% and 96%, respectively, whereas positive and negative predictive values were 88% and 100%, respectively.
  • Of the benign neoplasms, giant cell tumor of tendon sheath (17) and desmoid-type fibromatosis (7) were most common.
  • Seven nonsarcomas included melanoma (3), metastatic squamous carcinoma (2), and malignant lymphoma (2).

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  • (PMID = 20093231.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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45. Fresneau B, Oberlin O, Brugières L, Valteau-Couanet D, Patte C: [Malignant primary cardiac tumors in childhood and adolescence]. Arch Pediatr; 2010 May;17(5):495-501
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  • The majority of them are benign, with only 10% malignant.
  • Among malignant cardiac tumors, sarcoma (rhabdomyosarcoma, angiosarcoma, synovial sarcoma) and lymphoma (Burkitt's lymphoma, large B-cell lymphoma, lymphoblastic lymphoma) predominate.
  • We report here 3 observations of primary malignant cardiac tumors, 2 cases of sarcoma (angiosarcoma and synovial sarcoma) and 1 case of Burkitt's lymphoma.
  • For primary cardiac lymphoma, management should not be different from lymphoma in other locations.
  • Prognosis depends on histology and not lymphoma location, and so is better than the prognosis for sarcoma.
  • [MeSH-major] Burkitt Lymphoma / diagnosis. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Sarcoma, Synovial / diagnosis

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20338733.001).
  • [ISSN] 1769-664X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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46. Neumann-Silkow H, Görg C: [Differentiation of abdominal lymphadenoptahy with power Doppler sonography]. Rofo; 2010 Mar;182(3):229-34
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  • PURPOSE: Recent studies have reported high accuracy of power Doppler sonography (PDS) and color Doppler sonography (CDS) in the differentiation of benign and malignant peripheral superficial lymphadenopathy.
  • This study was conducted to determine whether PDS can differentiate benign from malignant abdominal lymph nodes on the basis of defined vascular patterns.
  • MATERIALS AND METHODS: We retrospectively evaluated 88 color pictures of abdominal lymph nodes (39 benign lymph nodes, 24 malignant lymphomas, 25 lymph node metastasis) done in the power Doppler mode.
  • The goal was to determine whether benign and malignant abdominal lymph nodes can be differentiated in power Doppler sonography on the basis of 9 defined vascular patterns.
  • RESULTS: Three vascular patterns showed a significantly (p < 0.05) higher appearance in malignant than in benign lymph nodes: aberrant vessel (specificity 87 %), avascular focus (specificity 92 %) and subcapsular vessel (specificity 100 %).
  • The vascular pattern hiliar vessel showed a significantly higher appearance in benign lymph nodes (specificity 87.8 %).
  • One vascular pattern (hiliar vessel) shows a significantly higher appearance in benign lymph nodes.
  • [MeSH-major] Abdominal Neoplasms / ultrasonography. Hodgkin Disease / ultrasonography. Lymph Nodes / ultrasonography. Lymphadenitis / ultrasonography. Lymphatic Metastasis / ultrasonography. Lymphoma, Non-Hodgkin / ultrasonography. Neoplasms, Unknown Primary / ultrasonography. Neovascularization, Pathologic / ultrasonography. Ultrasonography, Doppler, Color

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  • [Copyright] Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20084598.001).
  • [ISSN] 1438-9010
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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47. Mhawech-Fauceglia P, Herrmann FR, Bshara W, Odunsi K, Terracciano L, Sauter G, Cheney RT, Groth J, Penetrante R, Mhawech-Fauceglia P: Friend leukaemia integration-1 expression in malignant and benign tumours: a multiple tumour tissue microarray analysis using polyclonal antibody. J Clin Pathol; 2007 Jun;60(6):694-700
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  • [Title] Friend leukaemia integration-1 expression in malignant and benign tumours: a multiple tumour tissue microarray analysis using polyclonal antibody.
  • However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT).
  • AIM: To determine expression of FLI-1 in various benign and malignant neoplasms, by immunohistochemical analysis on 4323 tumours using multiple tumour microarrays, as well as on whole sections.
  • RESULTS: FLI-1 was expressed in 46/62 EWS/PNETs, 2/3 olfactory neuroblastomas, 7/102 small cell carcinomas of the lung, 10/34 MCCs, 1/14 rhabdomyosarcoma, 19/132 non-Hodgkin's lymphomas, 2/3 DSRCTs, and in 53/74 benign and malignant vascular tumours.

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  • (PMID = 16917000.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proto-Oncogene Protein c-fli-1
  • [Other-IDs] NLM/ PMC1955051
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48. Kannangara AP, Levitan D, Fleischer AB Jr: Six patients with early-stage cutaneous T-cell lymphoma successfully treated with topical 5-fluorouracil. J Drugs Dermatol; 2010 Aug;9(8):1017-8
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  • [Title] Six patients with early-stage cutaneous T-cell lymphoma successfully treated with topical 5-fluorouracil.
  • Topical 5-fluorouracil (5-FU) has been used in the treatment of various benign and malignant tumors of the skin, but only few address its therapeutic value on cutaneoues T-cell lymphoma. (CTCL).
  • [MeSH-major] Fluorouracil / therapeutic use. Lymphoma, T-Cell, Cutaneous / drug therapy. Skin Neoplasms / drug therapy

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  • (PMID = 20684155.001).
  • [ISSN] 1545-9616
  • [Journal-full-title] Journal of drugs in dermatology : JDD
  • [ISO-abbreviation] J Drugs Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; U3P01618RT / Fluorouracil
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49. Moghazy KM: Gastrosplenic fistula following chemotherapy for lymphoma. Gulf J Oncolog; 2008 Jan;(3):64-7
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  • [Title] Gastrosplenic fistula following chemotherapy for lymphoma.
  • Gastrosplenic fistula resulting from erosion of a primary splenic lymphoma is a very rare cause of massive upper gastrointestinal hemorrhage as compared to benign peptic ulcer disease, gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas.
  • A 50-year-old patient developed a gastrosplenic fistula during a course of chemotherapy for differentiated histiocytic lymphoma.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Gastric Fistula / chemically induced. Lymphoma, Large B-Cell, Diffuse / drug therapy. Splenic Diseases / chemically induced

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  • (PMID = 20084800.001).
  • [ISSN] 2078-2101
  • [Journal-full-title] The Gulf journal of oncology
  • [ISO-abbreviation] Gulf J Oncolog
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Kuwait
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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50. Zhang QH, Liu HS, Kong F: [Endoscopic endonasal surgery for tumors of petroclival region and infratemporal fossa]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2005 Jul;40(7):488-92
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  • There were 5 chordoma, 1 esthesioneuroblastoma, 1 chondrosarcoma, 1 lymphoma, 1 craniopharyngioma, 1 hemangioblastoma, 4 meningioma, 1 schwannoma, and 2 metastatic carcinoma.
  • The other cases with benign tumors were no recurrence.

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  • (PMID = 16200953.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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51. Moraitis D, Singh P, Jayadevan R, Cayten CG: Colonic wall thickening on computed tomography scan and clinical correlation. Does it suggest the presence of an underlying neoplasia? Am Surg; 2006 Mar;72(3):269-71
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  • One (3%) patient had lymphoma of the colon and two (6%) had benign polyps.

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  • (PMID = 16553131.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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52. Howard M, Dogan A: Diagnosis of Nodal Peripheral T-Cell Lymphomas. Surg Pathol Clin; 2010 Dec;3(4):955-88
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  • Lymph node-based peripheral T-cell lymphomas are rare and exhibit a morphologic spectrum that overlaps with reactive lymphoid hyperplasia, B-cell lymphomas, and Hodgkin lymphoma, presenting a diagnostic challenge.
  • Practical information to aid in distinguishing peripheral T-cell lymphomas from other hematologic malignancies and benign conditions is provided.

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 26839296.001).
  • [ISSN] 1875-9181
  • [Journal-full-title] Surgical pathology clinics
  • [ISO-abbreviation] Surg Pathol Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Anaplastic large cell lymphoma / Angioimmunoblastic / Lymph node hyperplasia / T-cell lymphoma
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53. Granados-García M, Cortés-Flores AO, del Carmen González-Ramírez I, Cano-Valdez AM, Flores-Hernández L, Aguilar-Ponce JL: Follicular neoplasms of the thyroid: importance of clinical and cytological correlation. Cir Cir; 2010 Nov-Dec;78(6):473-8
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  • Definitive report showed 45 benign (60%) and 30 malignant (40%) cases.
  • Benign cases included 29 goiters, 11 follicular adenomas, and 5 cases of thyroiditis.
  • Malignant cases were comprised of 12 papillary carcinomas, 4 follicular carcinomas, 3 papillary carcinomas-follicular variant, 1 lymphoma, 1 teratoma, 5 medullary carcinomas, 2 insular carcinomas, 1 anaplastic carcinoma and 1 metastatic breast carcinoma.
  • Tumor size of benign lesions was 3.43 ± 2.04 cm, and 4.67 ± 2.78 (p = 0.049) for malignant lesions.
  • Age was 46.95 ± 15.39 years for benign lesions and 48.67 ± 17.28 for malignant lesions (p = 0.66).

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  • (PMID = 21214982.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Mexico
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54. Farinha P, Masoudi H, Skinnider BF, Shumansky K, Spinelli JJ, Gill K, Klasa R, Voss N, Connors JM, Gascoyne RD: Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL). Blood; 2005 Sep 15;106(6):2169-74
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  • [Title] Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).
  • We studied the role of multiple biomarkers in determining outcome in follicular lymphoma (FL), concentrating in particular on the role of benign macrophages.
  • A multivariate Cox model that included the IPI score, the histologic grade, and the lymphoma-associated macrophage (LAM) score, showed IPI and LAM to be independent predictors of OS (P = .009 and P = .004, respectively).
  • [MeSH-major] Lymphoma, Follicular / diagnosis. Lymphoma, Follicular / mortality. Macrophages / cytology. Predictive Value of Tests


55. Alam K, Khan R, Jain A, Maheshwari V, Agrawal S, Chana RS, Harris SH: The value of fine-needle aspiration cytology in the evaluation of pediatric head and neck tumors. Int J Pediatr Otorhinolaryngol; 2009 Jul;73(7):923-7
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  • RESULTS: Benign lesions were found to be more common than the malignant variety, the commonest being soft tissue tumors (46.87%).
  • [MeSH-minor] Adolescent. Biopsy, Needle / methods. Child. Child, Preschool. False Negative Reactions. False Positive Reactions. Female. Humans. Infant. Lymphoma / diagnosis. Lymphoma / pathology. Male. Retrospective Studies. Sensitivity and Specificity. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / pathology

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  • (PMID = 19375806.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Ireland
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56. Leinweber B, Beltraminelli H, Kerl H, Cerroni L: Solitary small- to medium-sized pleomorphic T-cell nodules of undetermined significance: clinical, histopathological, immunohistochemical and molecular analysis of 26 cases. Dermatology; 2009;219(1):42-7
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  • The incongruity between the indolent clinical course and the worrying histopathological features poses difficulties in classifying these cases unambiguously as benign or malignant.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / pathology. Skin Neoplasms / pathology. T-Lymphocytes / pathology

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  • [Copyright] 2009 S. Karger AG, Basel.
  • (PMID = 19349695.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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57. Quer M, Pujol A, León X, López M, García J, Orús C, Sañudo JR: Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification. Acta Otorrinolaringol Esp; 2010 Jan-Feb;61(1):1-5
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  • [Title] Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification.
  • INTRODUCTION AND GOALS: At present different options co-exist for treating a benign tumour of the parotid gland, which has led to some confusion about the extent of resection performed in each case.
  • METHODS: We analyzed 44 patients who underwent surgery for clinically benign tumours of the parotid gland in our department between July, 2006, and December, 2008.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / surgery. Cysts / surgery. Diagnostic Errors. Female. Humans. Incidental Findings. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, B-Cell, Marginal Zone / surgery. Male. Middle Aged. Parotid Diseases / surgery. Retrospective Studies. Young Adult

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  • [Copyright] 2009 Elsevier España, S.L. All rights reserved.
  • (PMID = 19962123.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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58. Scagni P, Peisino MG, Bianchi M, Morello M, Sardi N, Linari A, Mastrodicasa L, Madon E, Pecco P: Kikuchi-Fujimoto disease is a rare cause of lymphadenopathy and fever of unknown origin in children: report of two cases and review of the literature. J Pediatr Hematol Oncol; 2005 Jun;27(6):337-40
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  • Kikuchi-Fujimoto disease, a benign and unusual self-limiting histiocytic necrotizing lymphadenitis of unknown origin, should be included in the differential diagnosis of lymphadenopathy and fever of unknown origin.
  • This disease mostly affects young Asian women and has rarely been reported in children, thus remaining a poorly recognized entity that is frequently confused with malignant lymphoma.

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  • [CommentIn] J Pediatr Hematol Oncol. 2007 Dec;29(12):864 [18090944.001]
  • [CommentIn] J Pediatr Hematol Oncol. 2006 Mar;28(3):163-4 [16679940.001]
  • (PMID = 15956890.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Coco C, Rizzo G, Manno A, Mattana C, Verbo A: Surgical treatment of small bowel neoplasms. Eur Rev Med Pharmacol Sci; 2010 Apr;14(4):327-33
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  • Benign small intestinal tumors (e.g., leiomyoma, lipoma, hamartoma, or desmoid tumor) usually are asymptomatic but may present with complications.
  • Primary malignancies of the small intestine, including adenocarcinoma, leiomyosarcoma, carcinoid, and lymphoma, are often symptomatic and may present with intestinal obstruction, jaundice, bleeding, or pain.
  • [MeSH-minor] Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Gastrointestinal Stromal Tumors / pathology. Gastrointestinal Stromal Tumors / surgery. Humans. Laparoscopy. Lymphoma / pathology. Lymphoma / surgery. Neoplasm Metastasis

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  • (PMID = 20496543.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 51
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60. Kelley TW, Prayson RA, Barnett GH, Stevens GH, Cook JR, Hsi ED: Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue arising in the lateral ventricle. Leuk Lymphoma; 2005 Oct;46(10):1423-7
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  • [Title] Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue arising in the lateral ventricle.
  • Extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT) lymphomas are a well-described type of low-grade B-cell non-Hodgkin lymphoma.
  • We recently encountered a case of an intracranial MALT lymphoma in a 53-year-old man who presented with persistent headaches and a seizure.
  • Histologically, there was a vaguely nodular, dense lymphoid infiltrate with occasional benign follicles colonized by marginal zone lymphoma, suggesting derivation from a focus of prior inflammation.
  • [MeSH-major] Brain Neoplasms / pathology. Lateral Ventricles / pathology. Lymphoma, B-Cell, Marginal Zone / pathology

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  • (PMID = 16194887.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Receptors, Complement 3d
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61. DeWitt J, Misra VL, Leblanc JK, McHenry L, Sherman S: EUS-guided FNA of proximal biliary strictures after negative ERCP brush cytology results. Gastrointest Endosc; 2006 Sep;64(3):325-33
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  • EUS-FNA (median, 4 passes; range, 1-11) demonstrated malignancy in 17 of 24 (71%) patients with findings showing adenocarcinoma (15), lymphoma (2), atypical cytology (3), or benign cells (4).
  • Pathology results from 8 of 24 (33%) patients who underwent surgery showed hilar cholangiocarcinoma (6), gallbladder cancer (1), and a benign, inflammatory stricture (1).

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  • [CommentIn] Gastrointest Endosc. 2006 Sep;64(3):334-7 [16923478.001]
  • (PMID = 16923477.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Tadini B, Repetto L, Guarino N, Lace R, Marras E, Bianchi M: Retroperitoneoscopic renal surgery in children: our experience. J Laparoendosc Adv Surg Tech A; 2006 Jun;16(3):305-7
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  • BACKGROUND: Laparoscopic renal surgery has become an accepted approach for benign disease in adult and pediatric urology.
  • Twenty-seven patients underwent unilateral retroperitoneal nephrectomy; 1 child with Denis Drash syndrome underwent transperitoneal bilateral nephrectomy; 2 children underwent renal cyst unroofing; and 1 child with lymphoma underwent retroperitoneal laparoscopic renal biopsy.
  • Indications for surgery were: renal function <9% in cases of unilateral nephrectomy; the prevention of renal neoplastic changes in the patient with Denys-Drash syndrome; symptomatic large renal cysts; and suspected lymphoma not diagnosed with a previous percutaneous biopsy.

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  • (PMID = 16796447.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Leuschner I: [Inflammatory myofibroblastic tumor]. Pathologe; 2010 Mar;31(2):106-8
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  • The tumors are associated with a benign behavior but recurrences occur in about one third of abdominal cases.

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  • (PMID = 20063099.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases; EC 2.7.10.1 / anaplastic lymphoma kinase
  • [Number-of-references] 6
  •  go-up   go-down


64. Hu XC, Bao LM, Zhu XZ, Irons RD, Fu H, Chen Y, Chen H, Zhao XM, Yang XM, Li J: [Cytogenetic and interphase FISH studies in the diagnosis of malignant lymphomas]. Zhonghua Zhong Liu Za Zhi; 2007 Jan;29(1):45-8
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  • OBJECTIVE: To evaluate the role of cytogenetic study and interphase FISH analysis in differential diagnosis of patients with clinical and/or cytological diagnosis as lymphoma or "suspicious for lymphoma".
  • RESULTS: Based on these studies, forty-four patients were diagnosed as Hodgkin's lymphomas ( HL) , 162 as Non-Hodgkin's lymphomas ( NHL) , 11 with benign diseases and 4 as other malignancies, while the remaining 2 cases were discarded due to tissue necrosis.
  • Using interphase FISH, abnormalities of immunoglobulin heavy chain gene (IGH) were detected in 6/44 (13.6%) and 83/162 (51.2%) in the HIL and NHL cases, respectively, while none was observed in 11 cases with a benign disease (P <0. 001).
  • [MeSH-major] Hodgkin Disease / diagnosis. In Situ Hybridization, Fluorescence / methods. Lymphoma, Non-Hodgkin / diagnosis

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  • (PMID = 17575693.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-bcl-2
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65. Cunha BA, Mickail N, Durie N, Pherez FM, Strollo S: Fever of unknown origin (FUO) caused by Kikuchi's disease mimicking lymphoma. Heart Lung; 2009 Sep-Oct;38(5):450-6
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  • [Title] Fever of unknown origin (FUO) caused by Kikuchi's disease mimicking lymphoma.
  • Kikuchi's disease (Kikuchi-Fujimoto disease) is also known as histiocytic necrotizing lymphadenitis, a benign, self-limited disorder usually in middle-aged women of Asian descent.
  • In middle-aged adults patients presenting with an FUO, the presence of otherwise unexplained cervical adenopathy should suggest the possibility of lymphoma or, rarely, Kikuchi's disease.
  • [MeSH-minor] Adult. Female. Humans. Lymphatic Diseases / diagnosis. Lymphoma / diagnosis

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  • (PMID = 19755197.001).
  • [ISSN] 1527-3288
  • [Journal-full-title] Heart & lung : the journal of critical care
  • [ISO-abbreviation] Heart Lung
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Hutchinson CB, Wang E: Kikuchi-Fujimoto disease. Arch Pathol Lab Med; 2010 Feb;134(2):289-93
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  • Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is a self-limited condition, characterized by benign lymphadenopathy with associated fevers and systemic symptoms.
  • Non-Hodgkin lymphoma and systemic lupus erythematosus should be ruled out before diagnosis of Kikuchi-Fujimoto disease, given the overlapped clinical and histologic features as well as the different therapeutic approaches.

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  • (PMID = 20121621.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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67. Tanko NM, Echejoh GO, Manasseh NA, Mandong MB, Uba AF: Paediatric solid tumours in Nigerian children: a changing pattern? Afr J Paediatr Surg; 2009 Jan-Jun;6(1):7-10
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  • Ninety-four (51%) were benign and 87 (49%) malignant.
  • Non Hodgkin lymphoma and Burkitt lymphoma accounted for 17 (19.5%) and 12 (13.8%), respectively.

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  • (PMID = 19661657.001).
  • [ISSN] 0974-5998
  • [Journal-full-title] African journal of paediatric surgery : AJPS
  • [ISO-abbreviation] Afr J Paediatr Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nigeria
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68. Asoglu O, Porter L, Donohue JH, Cha SS: Laparoscopy for the definitive diagnosis of intra-abdominal lymphoma. Mayo Clin Proc; 2005 May;80(5):625-31
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  • [Title] Laparoscopy for the definitive diagnosis of intra-abdominal lymphoma.
  • OBJECTIVE: To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma.
  • PATIENTS AND METHODS: The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed.
  • Among the 69 cases of lymphoma, 55 (80%) were diagnosed via laparoscopy only, 9 (13%) via laparotomy, and 5 (7%) with later procedures.
  • Of the remaining 25 patients, 7 had nonlymphoma disease (4 occult carcinomas, 1 multiple myeloma, 1 epithelioid leiomyosarcoma, and 1 neuroblastoma), and 18 had benign lymphadenopathy (no evidence of lymphoma with a mean follow-up of 53 months).
  • CONCLUSION: Laparoscopic lymph node biopsy safely provides adequate tissue for full histological evaluation on an outpatient basis in most patients with intra-abdominal lymphoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy / methods. Diagnosis, Differential. False Negative Reactions. Feasibility Studies. Female. Follow-Up Studies. Humans. Laparotomy. Lymphoma, Non-Hodgkin / pathology. Lymphoma, Non-Hodgkin / surgery. Male. Middle Aged. Reproducibility of Results. Retrospective Studies. Safety

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  • (PMID = 15887430.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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69. Shields CL, Shields JA: Conjunctival tumors in children. Curr Opin Ophthalmol; 2007 Sep;18(5):351-60
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  • Overall, 97% prove to be benign and only 3% are malignant.
  • RECENT FINDINGS: The most common malignancies include conjunctival lymphoma and melanoma.

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  • (PMID = 17700226.001).
  • [ISSN] 1040-8738
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 51
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70. Yepes JF, Mozaffari E, Ruprecht A: Case report: B-cell lymphoma of the maxillary sinus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Dec;102(6):792-5
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  • [Title] Case report: B-cell lymphoma of the maxillary sinus.
  • The radiographic manifestation of malignant lesions of the maxillary sinus on dental radiographs may be nonspecific, making it difficult to differentiate the lesion from disease of odontogenic origin or more benign sinus pathoses.
  • A case of B-cell lymphoma is reported.
  • [MeSH-major] Lymphoma, B-Cell / pathology. Maxillary Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology

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  • (PMID = 17138183.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Oudidi A, El-Alami MN, Boulaich M, Jazouli N, Kzadri M: [Primary sub-mandibular gland tumours: experience based on 68 cases]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):187-90
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  • RESULTS: 68 cases were reviewed comprising 37 benign and 31 malignant tumours (15 females and 33 males).
  • Pleomorphic adenoma (n= 32) were the most frequent benign tumours.
  • For malignant lesions (n= 31) the most frequent were: Adenoid cystic carcinoma (n= 10), epidermoid carcinoma (n= 5), adenocarcinoma (n= 5), mucoepidermoid carcinoma (n= 3), malignant non Hodgkinien lymphoma (n= 5).

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  • (PMID = 17007195.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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72. Liang J, Newman JG, Frank DM, Chalian AA: Cervical unicentric Castleman disease presenting as a neck mass: case report and review of the literature. Ear Nose Throat J; 2009 May;88(5):E8
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  • Although Castleman disease may be mistaken for a malignant process such as lymphoma, it is a benign condition that is curable with complete surgical resection.

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  • (PMID = 19444782.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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73. Gheith S, Boulay R, Cornfield D: Small lymphocytic lymphoma/chronic lymphocytic leukemia in a pelvic myelolipoma. Int J Clin Exp Pathol; 2009;2(1):95-8
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  • [Title] Small lymphocytic lymphoma/chronic lymphocytic leukemia in a pelvic myelolipoma.
  • Myelolipoma is a rare benign tumor composed of mature adipose tissue and normal hematopoietic elements.
  • On immunostains, the lymphoid aggregates showed positivity for CD20, CD5, and CD23, consistent with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL).
  • This case represents the first report of a myelolipoma involved by a non-Hodgkin lymphoma.
  • The likeliest scenario is that an unusual benign tumor (myelolipoma) was colonized by a relatively common systemic hematopoietic neoplasm SLL/CLL, producing a collision tumor.

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  • (PMID = 18830383.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Extra adrenal myelolipoma / chronic lymphocytic leukemia / lymphoma / non-Hodgkin lymphoma / small lymphocytic lymphoma
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74. Takahashi K, Al-Janabi NJ: Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging; 2010 Dec;32(6):1325-39
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  • We describe the clinical, pathological, and imaging findings of mediastinal tumors with focus on thymic hyperplasia, thymic epithelial tumors, and germ cell tumors, malignant lymphoma, and various cystic masses.
  • In mediastinal lymphomas, a residual mass is common after treatment and MRI provides important information in distinguishing viable tumors from residual benign masses.
  • [MeSH-minor] Adult. Carcinoma / pathology. Female. Humans. Lymphoma / pathology. Male. Middle Aged. Neoplasms, Germ Cell and Embryonal / pathology. Thymus Gland / pathology. Thymus Hyperplasia / pathology. Thymus Neoplasms / pathology

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  • [Copyright] Copyright © 2010 Wiley-Liss, Inc.
  • (PMID = 21105138.001).
  • [ISSN] 1522-2586
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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75. Siösteen AK, Celsing F, Jacobsson H: FDG uptake in a catheter-related thrombus simulating relapse of lymphoma. Clin Nucl Med; 2005 May;30(5):338-9
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  • [Title] FDG uptake in a catheter-related thrombus simulating relapse of lymphoma.
  • FDG-PET imaging was performed because of suspected recurrence of lymphoma of the chest.
  • Focal activity in relation to the tip of a venous catheter is very likely to have a benign etiology.
  • [MeSH-major] Catheterization / adverse effects. Fluorodeoxyglucose F18 / pharmacokinetics. Lymphoma / metabolism. Lymphoma / radionuclide imaging. Neoplasm Recurrence, Local / radionuclide imaging. Venous Thrombosis / etiology. Venous Thrombosis / radionuclide imaging

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  • (PMID = 15827407.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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76. Lopez-Beltran A, Cheng L: Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications. Hum Pathol; 2006 Nov;37(11):1371-88
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  • It is important for surgical pathologists to be aware of these morphological variants that, on occasion, may lead to misinterpretation as benign.
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Large Cell / pathology. Carcinoma, Papillary / pathology. Carcinoma, Small Cell / pathology. Carcinoma, Squamous Cell / pathology. Carcinoma, Transitional Cell / pathology. Choriocarcinoma / pathology. Diagnosis, Differential. Female. Humans. Lymphoma / pathology. Male. Mesothelioma / pathology. Middle Aged. Papilloma, Inverted / pathology. Paraganglioma / pathology. Plasmacytoma / pathology. Sarcoma / pathology. Urothelium

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  • (PMID = 16949919.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 107
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77. Amorena Muro E, Borda Celaya F, Martínez-Peñuela Virseda JM, Borobio Aguilar E, Oquiñena Legaz S, Jiménez Pérez FJ: [Analysis of the clinical benefits and cost-effectiveness of performing a systematic second-look gastroscopy in benign gastric ulcer]. Gastroenterol Hepatol; 2009 Jan;32(1):2-8
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  • [Title] [Analysis of the clinical benefits and cost-effectiveness of performing a systematic second-look gastroscopy in benign gastric ulcer].
  • INTRODUCTION: We analyzed the need to routinely perform a second gastroscopy after an initial diagnosis of benign gastric ulcer.
  • RESULTS: There were 178 benign ulcers (79%) and 48 malignant ulcers (21%).
  • Three new cases of MALT lymphoma and three new cases of gastric adenocarcinoma were diagnosed and could be treated with curative intent.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / economics. Adenocarcinoma / pathology. Cost-Benefit Analysis. Diagnosis, Differential. Early Diagnosis. Gastric Mucosa / pathology. Humans. Internship and Residency. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / economics. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / economics. Lymphoma, Non-Hodgkin / pathology. Medical Staff, Hospital. Precancerous Conditions / diagnosis. Precancerous Conditions / economics. Precancerous Conditions / pathology. Predictive Value of Tests. Reproducibility of Results. Retrospective Studies. Sensitivity and Specificity

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  • (PMID = 19174093.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Spain
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78. Inaba H, Suzuki S, Shigematsu S, Shinomiya K, Ohfusa H, Shimojo Y, Uehara T, Hashizume K: Leydig cell tumor and malignant lymphoma in a patient with nonclassical 21-hydroxylase deficiency. Intern Med; 2009;48(8):601-5
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  • [Title] Leydig cell tumor and malignant lymphoma in a patient with nonclassical 21-hydroxylase deficiency.
  • Five years earlier, he underwent simultaneous surgeries for an adrenal adenoma, a benign Leydig cell tumor (LCT), and a malignant lymphoma.
  • The genetic background of 21-OHD might contribute to the development of malignant lymphoma.
  • Such as a case of LCT and malignant lymphoma in a patient with 21-OHD seems to be rare.
  • [MeSH-major] Adrenal Hyperplasia, Congenital / complications. Adrenal Hyperplasia, Congenital / diagnosis. Leydig Cell Tumor / etiology. Lymphoma / etiology. Testicular Neoplasms / etiology


79. Fung MA: 'Epidermotropism' vs. 'exocytosis' of lymphocytes 101: definition of terms. J Cutan Pathol; 2010 May;37(5):525-9
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  • The terms 'epidermotropism' and 'exocytosis' are commonly used to describe intraepithelial lymphocytes in the mycosis fungoides (MF) variant of cutaneous T cell lymphoma (CTCL).
  • In definitions provided by 19 responders, 'epidermotropism' correlated with MF/CTCL, and 'exocytosis' correlated with benign conditions.

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  • (PMID = 20132423.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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80. Nguyen BD, Chivers SF: Tear of plantar fascia and tibiocalcaneal ligament with positive F-18 FDG PET findings. Clin Nucl Med; 2006 Nov;31(11):709-12
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  • Although PET/CT imaging provides the most comprehensive evaluation of cancer, coexisting hypermetabolic benign processes may interfere with the staging of aggressive malignancy such as melanoma and extranodal non-Hodgkin lymphoma.

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  • (PMID = 17053392.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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81. Hatzibougias D, Bobos M, Karayannopoulou G, Karkavelas G, Karapanagiotidis GT, Foroulis CN, Kostopoulos I: A rare tumoral combination, synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura. World J Surg Oncol; 2008;6:137
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  • [Title] A rare tumoral combination, synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura.
  • BACKGROUND: Coexistence of adenocarcinoma and mantle cell lymphoma in the same or different anatomical sites is extremely rare.
  • We present a case of incidental discovery of primary lung adenocarcinoma and mantle cell lymphoma involving the pleura, during an axillary thoracotomy performed for a benign condition.
  • Histologic examination of the stripped-off parietal pleura and of the bullectomy specimen revealed the synchronous occurrence of two distinct neoplasms, a lymphoma infiltrating the pleura and a primary, early lung adenocarcinoma.
  • The morphologic, immunophenotypic and genetic findings supported the diagnosis of primary lung adenocarcinoma (papillary subtype) coexisting with a non-Hodgkin, B-cell lineage, mantle cell lymphoma involving both, visceral and parietal pleura and without mediastinal lymph node involvement.
  • The neoplastic lymphoid cells showed the characteristic immunophenotype of mantle cell lymphoma and the translocation t(11;14).
  • CONCLUSION: This is the first reported case of a rare tumoral combination involving simultaneously lung and pleura, emphasizing at the incidental discovery of the two coexisting neoplasms during a procedure performed for a benign condition.
  • [MeSH-major] Adenocarcinoma / pathology. Lung Neoplasms / pathology. Lymphoma, Mantle-Cell / pathology. Neoplasms, Multiple Primary / pathology. Pleural Neoplasms / pathology

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  • (PMID = 19114021.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2629472
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82. Abouzied MM, Crawford ES, Nabi HA: 18F-FDG imaging: pitfalls and artifacts. J Nucl Med Technol; 2005 Sep;33(3):145-55; quiz 162-3
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  • 18F-FDG PET is emerging as a useful tool in the staging and restaging of many malignant neoplasms, such as lymphoma, lung cancer, colorectal cancer, head and neck cancer, breast cancer, and melanoma.
  • To accurately interpret 18F-FDG findings one must be familiar with the normal physiologic distribution of the tracer, frequently encountered physiologic variants, and benign pathologic causes of 18F-FDG uptake that can be confused with a malignant neoplasm.
  • The objectives of this article are to (a) describe the mechanism of 18F-FDG uptake, (b) list the patient preparation and pertinent patient history before 18F-FDG imaging, (c) describe the whole-body physiologic distribution of 18F-FDG, (d) list and discuss normal physiologic variants, and (e) list and discuss benign pathologic causes of 18F-FDG uptake.

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  • (PMID = 16145222.001).
  • [ISSN] 0091-4916
  • [Journal-full-title] Journal of nuclear medicine technology
  • [ISO-abbreviation] J Nucl Med Technol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 48
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83. Chumsri S, Tummala MK, Khna AM, Zhao XF, Rapoport AP: Persistent positron emission tomography positivity secondary to benign histiocytic proliferation after treatment of Hodgkin lymphoma. Leuk Lymphoma; 2007 Mar;48(3):616-8
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  • [Title] Persistent positron emission tomography positivity secondary to benign histiocytic proliferation after treatment of Hodgkin lymphoma.


84. Khedmat H, Taheri S: Characteristics and prognosis of post-transplant lymphoproliferative disorders within renal allograft: Report from the PTLD.Int. Survey. Ann Transplant; 2010 Jul-Sep;15(3):80-6
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  • Before development of multi-organ involvement allograft PTLD in renal transplant patients has a benign behavior; therefore it is crucial to evaluate renal recipients with initial symptoms of PTLDs.
  • [MeSH-minor] Adult. Female. Humans. Lymphoma / chemically induced. Lymphoma / complications. Lymphoma / etiology. Male. Middle Aged. Prognosis. Survival Analysis. Transplants / adverse effects

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  • (PMID = 20877272.001).
  • [ISSN] 2329-0358
  • [Journal-full-title] Annals of transplantation
  • [ISO-abbreviation] Ann. Transplant.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Poland
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85. Haverkamp MC, Scholte AJ, Holman ER, Jongbloed MR, Schippers EF, de Roos A, van der Wall EE, Poldermans D, Bax JJ, Schalij MJ: Contrast echocardiography as a useful additional diagnostic tool in evaluating a primary cardiac tumor. Eur J Echocardiogr; 2005 Oct;6(5):388-91
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  • The current report describes a case of a primary cardiac lymphoma.
  • For early and appropriate treatment of a cardiac mass it is not only important to determine its localization and extension but also to differentiate between malignant and benign lesions.
  • [MeSH-major] Echocardiography. Echocardiography, Transesophageal. Heart Neoplasms / ultrasonography. Lymphoma, Large B-Cell, Diffuse / ultrasonography

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  • (PMID = 16153561.001).
  • [ISSN] 1525-2167
  • [Journal-full-title] European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
  • [ISO-abbreviation] Eur J Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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86. Eros N, Károlyi Z, Marschalkó M, Kárpáti S, Matolcsy A: Clinical, histopathological, immunophenotypic and molecular analysis of 60 patients with cutaneous T-cell infiltrates with follow up of indeterminate cases to identify T-cell lymphoma. Pathol Oncol Res; 2008 Mar;14(1):63-7
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  • [Title] Clinical, histopathological, immunophenotypic and molecular analysis of 60 patients with cutaneous T-cell infiltrates with follow up of indeterminate cases to identify T-cell lymphoma.
  • To assess diagnostic value of complex histological, immunophenotypic and T-cell receptor gamma gene rearrangement analysis, skin biopsy specimen and peripheral blood samples of 60 patients with suspected cutaneous T-cell lymphoma were analyzed.
  • Our results indicate clear distinction between reactive dermatoses (benign cases, n = 31) and cutaneous T-cell lymphomas (lymphoma cases, n = 17).
  • [MeSH-major] Dermatitis / diagnosis. Lymphoma, T-Cell, Cutaneous / diagnosis. Mycosis Fungoides / diagnosis. Skin Neoplasms / diagnosis. T-Lymphocytes

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  • (PMID = 18392954.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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87. Mohamud SO, Motorwala SA, Daniel AR, Tworek JA, Shehab TM: Giant ileal inflammatory fibroid polyp causing small bowel obstruction: a case report and review of the literature. Cases J; 2008;1(1):341
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  • Benign disease is the typical cause in children and adolescents while malignant or adhesive disease is far more common in older patients.
  • Although cases of adult intussusception caused by benign processes are rare, there are reports of inflammatory fibroid polyps causing adult intussusception of the terminal ileum published in the literature.
  • CONCLUSION: Small bowel lesions include both malignant and benign etiologies.
  • The malignant etiologies include adenocarcinoma, carcinoid or lymphoma while benign lesions are typically lipomas, inflammatory polyps or adenomas.
  • Inflammatory fibroid polyps are rare, benign lesions that can occur anywhere within the gastrointestinal tract.

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  • (PMID = 19025593.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2596112
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88. Lee JY, Jang YD, Kim HK: The primary role of the otolaryngologist in managing pediatric sinonasal malignancies: an extranodal NK/T-cell lymphoma originating from the inferior turbinate mucosa of the nasal cavity. J Pediatr Hematol Oncol; 2008 May;30(5):401-4
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  • [Title] The primary role of the otolaryngologist in managing pediatric sinonasal malignancies: an extranodal NK/T-cell lymphoma originating from the inferior turbinate mucosa of the nasal cavity.
  • Recently, we observed a nasal extranodal natural killer/T-cell lymphoma in a 12-year-old girl with a 6-month history of right nasal obstruction.
  • In this case, we emphasize the importance of a complete endoscopic examination of the nasal cavity in a pediatric patient with unilateral nasal symptoms and the possible necessity of referral to an otolaryngologist to prevent misdiagnosis and management of the pathology as benign.
  • [MeSH-major] Killer Cells, Natural / pathology. Lymphoma, T-Cell / drug therapy. Lymphoma, T-Cell / radiotherapy. Nasal Mucosa / pathology. Paranasal Sinus Neoplasms / drug therapy. Paranasal Sinus Neoplasms / radiotherapy

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  • (PMID = 18458579.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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89. Kojima M, Nakamura N, Otuski Y, Itoh H, Ogawa Y, Kobayashi H, Nakamura S: Pulmonary lesion of idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia appears to be a cause of lymphoplasmacytic proliferation of the lung: a report of five cases. Pathol Res Pract; 2008;204(3):185-90
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  • Therapeutically, it is important to discriminate between pulmonary involvement of IPL and pulmonary benign or malignant pulmonary lymphoplasmacytic proliferation, particularly marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Lymphoma, B-Cell, Marginal Zone / pathology. Male. Middle Aged. Plasma Cells / pathology


90. Kallenberg MH, Gill RR, Factor RE, Bryar JM, Rubin RH, Jacobson FL, Marty FM: Diagnostic efficacy and safety of computed tomography-guided transthoracic needle biopsy in patients with hematologic malignancies. Acad Radiol; 2009 Nov;16(11):1408-15
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  • RATIONALE AND OBJECTIVES: The role of transthoracic needle biopsy (TTNB) in patients with hematologic malignancies, particularly in discriminating between malignant and benign etiologies, has not been well studied.
  • RESULTS: The most common underlying hematologic malignancy was non-Hodgkin lymphoma, in 20 patients (37.7%).

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  • (PMID = 19683945.001).
  • [ISSN] 1878-4046
  • [Journal-full-title] Academic radiology
  • [ISO-abbreviation] Acad Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Rofeim O, Gilbert BR: Long-term effects of cryopreservation on human spermatozoa. Fertil Steril; 2005 Aug;84(2):536-7
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  • We evaluated the long-term effects of cryopreservation on spermatozoa of men with testicular cancer, lymphoma, and benign conditions.

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  • (PMID = 16084905.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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92. Christensen JH, Abildgaard N, Plesner T, Nibe A, Nielsen O, Sørensen AG, Kerndrup GB, Leukemia/Lymphoma Study Group, Region of Southern Denmark: Interphase fluorescence in situ hybridization in multiple myeloma and monoclonal gammopathy of undetermined significance without and with positive plasma cell identification: analysis of 192 cases from the Region of Southern Denmark. Cancer Genet Cytogenet; 2007 Apr 15;174(2):89-99
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  • Interphase fluorescence in-situ hybridization (i-FISH) was used to investigate 192 patients with multiple myeloma (MM; n = 182) and benign monoclonal gammopathy of undetermined significance (MGUS; n = 10).

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  • (PMID = 17452249.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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93. Anderson L, Middleton WD, Teefey SA, Reading CC, Langer JE, Desser T, Szabunio MM, Mandel SJ, Hildebolt CF, Cronan JJ: Hashimoto thyroiditis: Part 2, sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis. AJR Am J Roentgenol; 2010 Jul;195(1):216-22
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  • [Title] Hashimoto thyroiditis: Part 2, sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis.
  • OBJECTIVE: The purpose of this article is to compare sonographic features of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis.
  • Patients with a sonographic appearance consistent with diffuse Hashimoto thyroiditis and with coexisting nodules that could be confirmed to be benign or malignant by fine-needle aspiration or surgical pathologic analysis were included in the study.
  • RESULTS: Among nodules within diffuse Hashimoto thyroiditis, 84% (69/82) were benign (35 nodular Hashimoto thyroiditis, 32 nodular hyperplasia, and two follicular adenoma), and 16% (13/82) were malignant (12 papillary carcinoma and one lymphoma).
  • Benign nodules were more likely to be hyperechoic (46% vs 9%), to have a halo (39% vs 15%), and to lack calcifications (88% vs 23%).
  • Benign nodules more often had ill-defined margins (36% vs 8%).
  • CONCLUSION: Sonographic features of benign and malignant nodules within diffuse Hashimoto thyroiditis are generally similar to the features typical of benign and malignant nodules in the general population.

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  • (PMID = 20566819.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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94. Greco L, Marino F, Troilo VL, Marzullo A, Gentile A: Gastric stump lymphoma after distal gastrectomy for benign peptic ulcer: Report of a case. Surg Today; 2006;36(11):985-8
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  • [Title] Gastric stump lymphoma after distal gastrectomy for benign peptic ulcer: Report of a case.
  • We report a case of primary non-Hodgkin gastric stump lymphoma, found in a 78-year-old man 30 years after a distal gastrectomy for a benign peptic ulcer.
  • The development of lymphoma in the gastric stump is rare.
  • Conversely, bile reflux and nitrite and N-nitrous compounds caused by abnormal bacterial growth in the gastric stump may play a role in inducing mucosa-associated lymphoid tissue lymphoma.
  • [MeSH-major] Gastrectomy / adverse effects. Gastric Stump. Lymphoma, B-Cell / etiology. Stomach Neoplasms / etiology. Stomach Ulcer / surgery

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  • (PMID = 17072720.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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95. Beland MD, Mayo-Smith WW, Dupuy DE, Cronan JJ, DeLellis RA: Diagnostic yield of 58 consecutive imaging-guided biopsies of solid renal masses: should we biopsy all that are indeterminate? AJR Am J Roentgenol; 2007 Mar;188(3):792-7
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  • The diagnosis of a benign lesion was made in 14 (27%) of 52 biopsies.
  • Lymphoma (1/58) and metastatic disease (1/58) accounted for the remaining two diagnostic biopsies.
  • The diagnosis of a benign lesion was made in 27% of diagnostic biopsies.

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  • (PMID = 17312070.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Kremer M, Horn T, Koch I, Dechow T, Gattenloehner S, Pfeiffer W, Quintanilla-Martínez L, Fend F: Quantitation of the JAK2V617F mutation in microdissected bone marrow trephines: equal mutational load in myeloid lineages and rare involvement of lymphoid cells. Am J Surg Pathol; 2008 Jun;32(6):928-35
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  • A heterozygous JAK2V617F mutation was detected in 3/8 "reactive" lymphoid nodule in patients with Ph-cMPD, whereas all concomitant non-Hodgkin lymphoma of B-cell type were negative.
  • The occasional detection of JAK2V617F in benign lymphocytes points to involvement of the lympho-myeloid stem cell.

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  • (PMID = 18551750.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.2 / JAK2 protein, human; EC 2.7.10.2 / Janus Kinase 2
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97. Killian JK, Bilke S, Davis S, Walker RL, Killian MS, Jaeger EB, Chen Y, Hipp J, Pittaluga S, Raffeld M, Cornelison R, Smith WI Jr, Bibikova M, Fan JB, Emmert-Buck MR, Jaffe ES, Meltzer PS: Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome. Cancer Res; 2009 Feb 1;69(3):758-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome.
  • Emerging technologies allow broad profiling of the cancer genome for differential DNA methylation relative to benign cells.
  • Herein, bisulfite-modified DNA from lymph nodes with either reactive hyperplasia or follicular lymphoma (FL) were analyzed using a commercial C/UpG genotyping assay.
  • [MeSH-major] Lymph Nodes / pathology. Lymphoma, Follicular / genetics. Lymphoma, Follicular / pathology

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  • (PMID = 19155300.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 1HG84L3525 / Formaldehyde
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98. DeWitt J, LeBlanc J, McHenry L, McGreevy K, Sherman S: Endoscopic ultrasound-guided fine-needle aspiration of ascites. Clin Gastroenterol Hepatol; 2007 May;5(5):609-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Transgastric (n = 55) or transduodenal (n = 5) EUS-guided paracentesis (mean, 8.9; range, 1-40 mL) revealed malignancy in 16 (27%) from primary pancreatic (n = 9), gastric (n = 2), urothelial (n = 1), esophageal (n = 1), gallbladder (n = 1), bile duct (n = 1) cancer, and lymphoma (n = 1).
  • The cytology from 2 patients was atypical (1 suspicious for malignancy and 1 considered reactive) and the remaining 42 were benign.

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  • (PMID = 17336593.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Zaman S, Majid S, Hussain M, Chughtai O, Mahboob J, Chughtai S: A retrospective study of ovarian tumours and tumour-like lesions. J Ayub Med Coll Abbottabad; 2010 Jan-Mar;22(1):104-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The study was a retrospective review of all cases of ovarian cancer, benign ovarian neoplasm and functional ovarian cysts received during Jan-Dec 2008 at Chughtai's Lahore Laboratory.
  • Among the neoplastic tumours 78.70% were benign and 21.29% were malignant.
  • Benign serous cysts were the commonest benign tumour followed by mature cystic teratoma and mucinous cyst.
  • Krukenberg tumour, tumour metastatic to ovaries and non-Hodgkins lymphoma was also diagnosed during this period.

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  • (PMID = 21409917.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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100. Davidson T, Goitein O, Avigdor A, Zwas ST, Goshen E: 18F- FDG-PET/CT for the diagnosis of tumor thrombosis. Isr Med Assoc J; 2009 Feb;11(2):69-73
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  • Underlying pathologies included pancreatic, colorectal, renal cell, and head-neck squamous cell carcinoma, as well as lymphoma (4 patients).
  • Accuracy of PET/CT to differentiate between tumor thrombosis and benign VTE was 100% in this small study.
  • [MeSH-minor] Adult. Aged. Carcinoma / radiography. Carcinoma / radionuclide imaging. Cohort Studies. Diagnosis, Differential. Digestive System Neoplasms / radiography. Digestive System Neoplasms / radionuclide imaging. Female. Fluorodeoxyglucose F18. Humans. Kidney Neoplasms / radiography. Kidney Neoplasms / radionuclide imaging. Lymphoma / radiography. Lymphoma / radionuclide imaging. Male. Middle Aged. Predictive Value of Tests. Radiopharmaceuticals. Retrospective Studies

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  • (PMID = 19432032.001).
  • [ISSN] 1565-1088
  • [Journal-full-title] The Israel Medical Association journal : IMAJ
  • [ISO-abbreviation] Isr. Med. Assoc. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Israel
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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