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1. Palanivelu C, Rangarajan M, Parthasarathi R, Senthilkumar R: Laparoscopic resection for benign tumors of the stomach. JSLS; 2007 Jan-Mar;11(1):81-6
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  • [Title] Laparoscopic resection for benign tumors of the stomach.
  • BACKGROUND: Of all gastric tumors, less than 5% are benign.
  • The traditional treatment of symptomatic and some asymptomatic benign tumors has ranged from mucosal resection to limited gastrectomy.
  • Since the advent of laparoscopy, many different laparoscopic approaches to resection of benign gastric tumors have now been described in the literature.
  • METHODS: We reviewed our experience with laparoscopic approaches to surgical resection of 7 benign gastric tumors.
  • The seventh patient underwent a Billroth I procedure because he had leiomyoma at the antrum.
  • DISCUSSION: Laparoscopic approach is slowly carving a niche for itself in the treatment of benign tumors of the stomach.
  • The basic principles are obtaining a precise preoperative pathological diagnosis; accurate tumor localization; achievement of tumor-free margins; avoidance of spillage of stomach contents, careful dissection of tumors in the esophagogastric junction, and preventing tumor seeding.
  • CONCLUSION: Based on ours and other studies, laparoscopic resection of benign gastric tumors is safe and feasible.

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  • (PMID = 17651562.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015806
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2. Finnell CW, Madan AK, Ternovits CA, Menachery SJ, Tichansky DS: Unexpected pathology during laparoscopic bariatric surgery. Surg Endosc; 2007 Jun;21(6):867-9
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  • The findings included lesions on the small bowel (n = 3), stomach (n = 4), and liver (n = 2).
  • The final pathology showed gastric leiomyomas (n = 2), gastric gastrointestinal stromal cell tumors (n = 2), ectopic pancreatic tissue (n = 2), arteriovenous malformation (n = 1), biliary adenoma (n = 1), and fibrosed hemangioma (n = 1).

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  • (PMID = 17149553.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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3. Iaurova NV, Legostaeva TB, Kordakova AN, Viatchanin OV: [Capacities of ultrasound study in the diagnosis of diffuse gastric carcinoma]. Vestn Rentgenol Radiol; 2007 Jul-Aug;(4):30-8
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  • [Title] [Capacities of ultrasound study in the diagnosis of diffuse gastric carcinoma].
  • By using 237 verified cases of diffuse carcinoma and benign diseases of the stomach as an example, the authors assess the capacities of routine transabdominal ultrasound study (USS) of the stomach in the diagnosis of tumors and present their modification of the procedure facilitating the imaging of problem areas.
  • In the authors' opinion, the symptoms of thickening of the wall of the stomach and abnormalities in its normal five-layered structure indicate diffuse gastric carcinoma.
  • [MeSH-major] Carcinoma / ultrasonography. Leiomyoma / ultrasonography. Stomach Neoplasms / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Diagnostic Errors. Humans. Neoplasm Staging

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  • (PMID = 18634303.001).
  • [ISSN] 0042-4676
  • [Journal-full-title] Vestnik rentgenologii i radiologii
  • [ISO-abbreviation] Vestn Rentgenol Radiol
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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4. Andreano M, D'Ambrosio V, Antropoli M, Fioretto R, Vicenzo L, Clemente M: [Mesenteric Castleman's disease and inflammatory fibroid polyp of the stomach: a case report and review of the literature]. Chir Ital; 2009 Mar-Apr;61(2):241-7
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  • [Title] [Mesenteric Castleman's disease and inflammatory fibroid polyp of the stomach: a case report and review of the literature].
  • Castleman's disease is a very rare disease that causes many problems both in diagnosis and therapy.
  • An inflammatory fibroid polyp is a very rare benign lesion that can develop anywhere in the gastrointestinal tract.
  • Such polyps are most commonly found in the gastric antrum and usually occur in 50- to 60-year-old people.
  • The authors report the unusual finding of mesenteric Castleman's disease and an inflammatory fibroid polyp of the stomach in a 41-year-old woman.
  • [MeSH-major] Giant Lymph Node Hyperplasia / diagnosis. Leiomyoma / diagnosis. Mesentery / pathology. Polyps / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Treatment Outcome

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  • (PMID = 19537001.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 36
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5. Cheng B, Zhong L, Ding F, Xie HP, Wang Y, Yang YZ, Liu M, Wan J: [A comparative study of the diagnostic value of endoscopic ultrasonography with pathological features of upper gastrointestinal mesenchymal tumors]. Zhonghua Nei Ke Za Zhi; 2009 Sep;48(9):724-8
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  • Thirty-four cases were diagnosed as leiomyoma (47.2%) and 1 case as schwannoma (1.4%).
  • EUS showed that 38 cases were originated from the muscularis mucosae layer; 33 of them were leiomyoma and 5 stromal tumor.
  • Thirty-two cases were gastric GIMTs, EUS showed that 2 cases originating from the muscularis mucosae layer were gastric stromal tumor.
  • Of the 30 cases originating from the muscularis propria layer, 28 cases were stromal tumor, 1 case was leiomyoma and 1 case was schwannoma.
  • The sensitivity and the specificity of EUS in distinguishing benign and malignant stromal tumors according to sonographic characteristics were 81.0% and 93.8% respectively.
  • CONCLUSION: Stromal tumor is more common in stomach mesenchymal neoplasms and is more often originated from the muscularis propria layer in EUS; leiomyoma is more common in esophagus and is more often originated from the muscularis mucosae layer.
  • The diagnostic sensitivity and specificity of EUS are high in distinguishing benign and malignant character of upper digestive tract GIMTs.

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  • (PMID = 20079206.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] China
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6. Kim BC, Cheon JH, Lee SK, Kim TI, Kim H, Kim WH: Needle knife-assisted endoscopic polypectomy for a large inflammatory fibroid colon polyp by making its stalk into an omega shape using an endoloop. Yonsei Med J; 2008 Aug 30;49(4):680-6
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  • Colonic inflammatory fibroid polyp (IFP) is an uncommon benign polypoid lesion, which is composed of fibroblasts, numerous small vessels and edematous connective tissue with marked eosinophilic inflammatory cell infiltration.
  • This condition is frequently detected in the stomach and small intestine, but uncommon in the colon.
  • Although IFP is a benign lesion, surgical resections are performed in most colonic cases because the polyps are usually too large to resect endoscopically.
  • [MeSH-major] Colonic Polyps / pathology. Colonic Polyps / surgery. Colonoscopy / methods. Leiomyoma / surgery

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  • (PMID = 18729316.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2615300
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7. Tagaya N, Kasama K, Suzuki N, Taketsuka S, Horie K, Kubota K: Simultaneous laparoscopic treatment for diseases of the gallbladder, stomach, and colon. Surg Laparosc Endosc Percutan Tech; 2005 Jun;15(3):169-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous laparoscopic treatment for diseases of the gallbladder, stomach, and colon.
  • We describe a successful simultaneous laparoscopic treatment of a gallstone and gastric and colonic neoplasms.
  • Gastroscopy revealed a 3-cm protruding submucosal tumor in the gastric fundus and colonoscopy revealed a 2-cm sessile lesion in the sigmoid colon.
  • He underwent simultaneous laparoscopic treatment of the 3 organs because of the high risk of perforation or bleeding after gastric or colonic resection.
  • The laparoscopic procedures consisted of cholecystectomy, partial stapled resection of the gastric fundus, and partial resection of the sigmoid colon.
  • The histopathologic diagnoses were chronic cholecystitis, leiomyoma of the stomach, and tubulovillous adenoma with severe dysplasia of the colon.
  • [MeSH-major] Adenoma, Villous / surgery. Cholecystolithiasis / epidemiology. Cholecystolithiasis / surgery. Colonic Neoplasms / surgery. Laparoscopy. Leiomyoma / surgery. Stomach Neoplasms / surgery

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  • (PMID = 15956904.001).
  • [ISSN] 1530-4515
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Rotstein DS, Harms CA, Lovewell GN, Hohn AA: Gastric leiomyoma in a free-living Atlantic bottlenosed dolphin (Tursiops truncatus). Vet Rec; 2007 Jan 27;160(4):130-1
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  • [Title] Gastric leiomyoma in a free-living Atlantic bottlenosed dolphin (Tursiops truncatus).
  • [MeSH-major] Bottle-Nosed Dolphin. Leiomyoma / veterinary. Stomach Neoplasms / veterinary
  • [MeSH-minor] Animals. Animals, Wild. Diagnosis, Differential. Male

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  • (PMID = 17259457.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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9. Sidhu R, McAlindon ME, Leeds JS, Skilling J, Sanders DS: The role of serum chromogranin A in diarrhoea predominant irritable bowel syndrome. J Gastrointestin Liver Dis; 2009 Mar;18(1):23-6
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  • One patient (3.7%) had a gastric adenocarcinoma.
  • In the other 7, there were no cases of carcinoid, n=1 gastric leiomyoma, n=1 rectal tumour and 4 patients had persistently elevated CgA levels but with improvement of symptoms.

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  • (PMID = 19337629.001).
  • [ISSN] 1841-8724
  • [Journal-full-title] Journal of gastrointestinal and liver diseases : JGLD
  • [ISO-abbreviation] J Gastrointestin Liver Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Chromogranin A; 0 / Gastrointestinal Agents; RWM8CCW8GP / Octreotide
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10. Beye MD, Calton B, Launoy A, Pottecher T, Sall KB: [Role of MRI in the diagnostic of Gayet Wernicke's encephalopathy (GWE) after gastrectomy and parenteral nutrition]. Dakar Med; 2005;50(1):33-6
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  • GWE is rarely described after gastric surgery following parenteral nutrition.
  • She was operated 8 days before for gastric leiomyoma and underwent partial gastrectomy.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Peritonitis / surgery. Reoperation. Thiamine / therapeutic use. Thiamine Deficiency / complications. Treatment Outcome

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  • (PMID = 16190123.001).
  • [ISSN] 0049-1101
  • [Journal-full-title] Dakar médical
  • [ISO-abbreviation] Dakar Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Senegal
  • [Chemical-registry-number] X66NSO3N35 / Thiamine
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11. Galbfach PJ, Narbutt PG, Mik MŁ, Trzciński R, Dziki AJ: [Inflammatory fibroid polyp of the stomach--a case report]. Pol Merkur Lekarski; 2009 Feb;26(152):125-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Inflammatory fibroid polyp of the stomach--a case report].
  • Inflammatory fibroid polyp of the stomach is a rare benign mass of unknown etiology, mostly located within the pyloric area.
  • We report a case of 50-year-old woman with a large inflammatory fibroid polyp with a diameter of 60 x 50 x 40 mm imitating benign gastric tumour.
  • Clinical manifestation of large inflammatory fibroid polyp of the stomach can imitate symptoms of gastric cancer.
  • [MeSH-major] Leiomyoma / diagnosis. Polyps / diagnosis. Stomach Neoplasms / diagnosis

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  • (PMID = 19388517.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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12. Lee EJ, Kim TD, Oh HA, Lee HC, Kim JH, Jang BI, Kim TN, Chung MK, Bae YK: [Is the invasive approach for all the upper gastrointestinal mesenchymal tumors necessary?]. Korean J Gastroenterol; 2005 Jun;45(6):387-93
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  • RESULTS: Mesenchymal tumors consisted of thirty-six gastrointestinal stromal tumors (GISTs), 20 leiomyomas and 3 schwannomas.
  • All the esophageal tumors were leiomyoma (12/12, 100%).
  • In stomach, there were 32 GISTs (76.2%), 7 leiomyomas (16.7%) and 3 schwannomas (7.1%).
  • And there were 4 GISTs (80.0%) and 1 leiomyoma (20.0%) in duodenum.
  • Tumors less than 1 cm in maximal diameter were leiomyoma or GISTs with very low risk of aggressive behavior.
  • The invasive approach for every esophageal submucosal tumor is not necessary unless the size is very large, because most of them are benign in nature.
  • However, the gastric submucosal tumor with more than 1 cm in diameter should be carefully and regularly followed up or biopsied because it cannot be assumed to be benign for any GIST more than 1 cm in size at the present time, safely.
  • [MeSH-minor] Adult. Aged. Endoscopy, Gastrointestinal. Female. Humans. Leiomyoma / pathology. Male. Middle Aged. Neurilemmoma / pathology. Upper Gastrointestinal Tract

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  • (PMID = 15973072.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
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13. Daum O, Hatlova J, Mandys V, Grossmann P, Mukensnabl P, Benes Z, Michal M: Comparison of morphological, immunohistochemical, and molecular genetic features of inflammatory fibroid polyps (Vanek's tumors). Virchows Arch; 2010 May;456(5):491-7
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  • Vanek's tumor (inflammatory fibroid polyp) is a rare benign lesion occurring throughout the digestive tract.
  • Recently, mutations in platelet-derived growth factor receptor alpha (PDGFRA) were reported in gastric and small intestinal Vanek's tumors.
  • Six Vanek's tumors harbored activating mutations in PDGFRA exons 12 (n = 5) and 18 (n = 1) respectively: S566_E571delinsK (n = 1), S566_E571delinsR (n = 4), and D842 del (n = 1).
  • [MeSH-major] Intestinal Diseases / pathology. Leiomyoma / genetics. Leiomyoma / pathology. Polyps / genetics. Polyps / pathology. Receptor, Platelet-Derived Growth Factor alpha / genetics. Stomach Diseases / pathology

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  • (PMID = 20393746.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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14. Tokunaga M, Ohyama S, Fujimoto Y, Hiki N, Fukunaga T, Yamamoto N, Yamaguchi T: Simultaneous adenocarcinoma and leiomyoma of the stomach presenting as a collision tumor. Clin J Gastroenterol; 2009 Dec;2(6):394-397
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  • [Title] Simultaneous adenocarcinoma and leiomyoma of the stomach presenting as a collision tumor.
  • Preoperative esophagogastroduodenoscopy revealed a submucosal tumor with ulcer formation near the esophagogastric junction of the stomach.
  • Histopathological examination of the resected specimen revealed both adenocarcinoma and leiomyoma presenting as a collision tumor.
  • Preoperative accurate histopathological diagnosis of a gastric submucosal tumor is generally difficult.
  • Consequently, surgical resection of large gastric submucosal tumors may be indicated in the absence of histopathological confirmation of the diagnosis.
  • However, in this case preoperative histopathological diagnosis enabled surgeons to perform the appropriate surgery.

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  • (PMID = 26192793.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Adenocarcinoma / Collision tumor / Gastric cancer / Leiomyoma
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15. Kim GH, Park DY, Kim S, Kim DH, Kim DH, Choi CW, Heo J, Song GA: Is it possible to differentiate gastric GISTs from gastric leiomyomas by EUS? World J Gastroenterol; 2009 Jul 21;15(27):3376-81
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  • [Title] Is it possible to differentiate gastric GISTs from gastric leiomyomas by EUS?
  • AIM: To evaluate the ultrasonography (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.
  • METHODS: We evaluated the endoscopic EUS features in 53 patients with gastric mesenchymal tumors confirmed by histopathologic diagnosis.
  • The GISTs were classified into benign and malignant groups according to the histological risk classification.
  • RESULTS: Immunohistochemical analyses demonstrated 7 leiomyomas and 46 GISTs.
  • Inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer appeared more frequently in the GISTs than in the leiomyomas (P < 0.05).
  • CONCLUSION: EUS may help to differentiate gastric GISTs from gastric leiomyomas.
  • [MeSH-major] Gastrointestinal Stromal Tumors / ultrasonography. Leiomyoma / ultrasonography. Stomach Neoplasms / ultrasonography

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  • (PMID = 19610138.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2712898
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16. Lee IL, Lin PY, Tung SY, Shen CH, Wei KL, Wu CS: Endoscopic submucosal dissection for the treatment of intraluminal gastric subepithelial tumors originating from the muscularis propria layer. Endoscopy; 2006 Oct;38(10):1024-8
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  • [Title] Endoscopic submucosal dissection for the treatment of intraluminal gastric subepithelial tumors originating from the muscularis propria layer.
  • BACKGROUND AND STUDY AIMS: Subepithelial tumors of the stomach used to be considered as benign, but they do have malignant potential, especially when they originate from the muscularis propria layer.
  • ESD using an insulated-tip knife was used to remove gastric subepithelial tumors from the muscularis propria where this was possible.
  • Endoscopic mucosal resection using a suction and cap method ("EMR-c") was used to obtain a sufficiently large specimen for tissue diagnosis if complete resection by ESD was not possible.
  • The histological diagnosis was gastrointestinal stromal tumor for eight lesions and leiomyoma for four tumors.
  • CONCLUSIONS: ESD can be used for the resection of intraluminal gastric subepithelial tumors and could replace treatment by surgical resection in some cases.
  • EMR-c is an alternative method that can be used to obtain sufficient tumor tissue for histological diagnosis if complete resection by ESD fails.
  • [MeSH-major] Endoscopy, Gastrointestinal / methods. Gastric Mucosa / surgery. Gastrointestinal Stromal Tumors / surgery. Leiomyoma / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Endosonography. Female. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 17058168.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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17. Tivadar B, Serban B, Mircea M, Tivadar B Jr, Leonard A, Daniela P, Simona M: Late hepatic metastasis in the evolution of gastrointestinal stromal tumors. Hepatogastroenterology; 2010 Jan-Feb;57(97):95-7
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  • We here by present two cases of gastro-intestinal stromal tumours one with gastric location and one jejunal tumor with ulceration and hemorrhage, of small sizes, initially diagnosed as benign but developing in the late evolution liver metastases.
  • [MeSH-major] Gastrointestinal Stromal Tumors / pathology. Jejunal Neoplasms / pathology. Leiomyoma / pathology. Liver Neoplasms / secondary. Stomach Neoplasms / pathology


18. Dundr P, Povýsil C, Tvrdík D: Leiomyoma of the gastrointestinal tract with intracytoplasmic inclusion bodies. Report of three cases. Cesk Patol; 2006 Jul;42(3):139-44
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  • [Title] Leiomyoma of the gastrointestinal tract with intracytoplasmic inclusion bodies. Report of three cases.
  • We report three cases of leiomyoma of the gastrointestinal tract with intracytoplasmic inclusion bodies similar to those characteristic of inclusion body fibromatosis (IBF).
  • The first two cases represent leiomyoma of the stomach: one in a 70-year-old female and the other in a 72-year-old female.
  • In the third case the leiomyoma was located in the esophagus of a 63-year-old male and inclusion bodies in this case were rare.
  • [MeSH-major] Esophageal Neoplasms / pathology. Inclusion Bodies / pathology. Leiomyoma / pathology. Stomach Neoplasms / pathology

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  • (PMID = 16955562.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Actins; 68238-35-7 / Keratins
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19. Agaimy A, Bihl MP, Tornillo L, Wünsch PH, Hartmann A, Michal M: Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis. Am J Surg Pathol; 2010 Feb;34(2):271-8
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  • [Title] Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis.
  • Calcifying fibrous tumor (CFT) is a rare benign mesenchymal tumor composed of hyalinized fibrous tissue with interspersed bland fibroblastic spindled cells, scattered psammomatous, and/or dystrophic calcifications and variably prominent mononuclear inflammatory infiltrate.
  • To date, 6 gastric and 3 intestinal CFTs have been reported.
  • We analyzed 7 gastric CFTs including 6 new cases.
  • Most tumors originated in the gastric body (6/7).
  • In none of the cases were there remnants of burnt-out GIST, inflammatory fibroid polyp, inflammatory myofibroblastic tumor, leiomyoma, schwannoma, or other specific lesion.
  • Gastric CFTs are distinct from sclerosing GIST and other mesenchymal gut lesions and may represent a localized inflammatory fibrosclerosis in response to immune-mediated or other-type tissue injury affecting the muscularis propria.
  • [MeSH-major] Calcinosis / pathology. Neoplasms, Fibrous Tissue / pathology. Stomach Neoplasms / pathology

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  • (PMID = 20090503.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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20. Brown TH, Menon VS, Richards DG, Griffiths AP: Gastrointestinal bleeding in a pregnant woman: mucinous cystic neoplasm of pancreas mimicking gastrointestinal stromal tumor of stomach. J Hepatobiliary Pancreat Surg; 2009;16(5):681-3
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  • [Title] Gastrointestinal bleeding in a pregnant woman: mucinous cystic neoplasm of pancreas mimicking gastrointestinal stromal tumor of stomach.
  • A 38-year-old woman presented in early pregnancy with anemia due to an ulcerated gastric tumor which had the typical clinical presentation and endoscopic appearance of a gastric leiomyoma or gastrointestinal stromal tumor.
  • Review of the literature shows that both gastrointestinal hemorrhage and infiltration of stomach are infrequent complications of this tumor.
  • [MeSH-major] Gastrointestinal Stromal Tumors / diagnosis. Neoplasms, Cystic, Mucinous, and Serous / diagnosis. Pancreatic Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Pregnancy Outcome. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Female. Gastric Mucosa / pathology. Gastrointestinal Hemorrhage / diagnosis. Gastrointestinal Hemorrhage / etiology. Gastroscopy / methods. Humans. Immunohistochemistry. Pregnancy. Pregnancy Trimester, First. Risk Assessment. Treatment Outcome

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  • (PMID = 19669687.001).
  • [ISSN] 1436-0691
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 8
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21. Lee MJ, Lim JS, Kwon JE, Kim H, Hyung WJ, Park MS, Kim MJ, Kim KW: Gastric true leiomyoma: computed tomographic findings and pathological correlation. J Comput Assist Tomogr; 2007 Mar-Apr;31(2):204-8
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  • [Title] Gastric true leiomyoma: computed tomographic findings and pathological correlation.
  • OBJECTIVE: This study describes the computed tomographic (CT) findings of true leiomyomas in the stomach.
  • METHODS: Eleven patients with histopathologically proven gastric true leiomyomas were finally enrolled.
  • We retrospectively reviewed the CT findings of gastric true leiomyomas for the following considerations: location, morphological features (size, contour, tumor growth pattern, and enhancement pattern), and ancillary findings (ulceration and calcification).
  • RESULTS: All leiomyomas were in the cardia, with an average tumor size of 36 mm (range, 13-47 mm).
  • CONCLUSIONS: In conclusion, gastric leiomyomas are mainly located in the cardia and usually appeared as homogenous low attenuated masses on computed tomography.
  • [MeSH-major] Leiomyoma / diagnosis. Stomach Neoplasms / diagnosis. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Aged. Contrast Media / administration & dosage. Female. Humans. Iohexol / analogs & derivatives. Male. Middle Aged. Observer Variation. Radiographic Image Enhancement / methods. Retrospective Studies. Stomach / radiography

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  • (PMID = 17414754.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 182ECH14UH / iobitridol; 4419T9MX03 / Iohexol
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22. Chang X, Han J, Pang L, Zhao Y, Yang Y, Shen Z: Increased PADI4 expression in blood and tissues of patients with malignant tumors. BMC Cancer; 2009;9:40
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  • However, PADI4 expression was not observed in benign leiomyomas of stomach, uterine myomas, endometrial hyperplasias, cervical polyps, teratomas, hydatidiform moles, trophoblastic cell hyperplasias, hyroid adenomas, hemangiomas, lymph hyperplasias, schwannomas, neurofibromas, lipomas, and cavernous hemangiomas of the liver.
  • Quantitative PCR and western blot analysis showed higher PADI4 expression in gastric adenocarcinomas, lung adenocarcinomas, hepatocellular carcinomas, esophageal squamous cell cancers and breast cancers (n = 5 for each disease) than in the surrounding healthy tissues.
  • ELISA detected increased PADI4 and cAT levels in the blood of patients with various malignant tumors compared to those in patients with chronic inflammation and benign tumors.

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  • (PMID = 19183436.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antithrombins; 0 / Neoplasm Proteins; 29VT07BGDA / Citrulline; EC 3.- / Hydrolases; EC 3.5.3.15 / peptidylarginine deiminase type IV
  • [Other-IDs] NLM/ PMC2637889
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23. Ozdil B, Akkiz H, Kece C, Sandikci M: Endoscopic alcohol injection therapy of giant gastric leiomyomas: an alternative method to surgery. Can J Gastroenterol; 2010 Sep;24(9):533-5
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  • [Title] Endoscopic alcohol injection therapy of giant gastric leiomyomas: an alternative method to surgery.
  • Leiomyomas are the most common benign mesenchymal tumours of the upper gastrointestinal tract.
  • The treatment of esophageal leiomyoma has been enhanced by improvements in diagnostic and therapeutic endoscopic techniques; however, the same cannot be said for gastric leiomyoma management.
  • The present article describes the management of two cases involving giant gastric leiomyomas that were&nbsp; successfully treated using endoscopic injection of alcohol.
  • To the authors' knowledge, the present study is the first report of the treatment of such hemorrhagic gastric tumours using this alternative and low-cost technique.
  • Endoscopic local ethanol injection may be the treatment of choice in carefully selected patients with hemorrhagic leiomyomas of the upper gastrointestinal tract.
  • [MeSH-major] Ethanol / administration & dosage. Gastroscopy / methods. Leiomyoma / therapy. Stomach Neoplasms / therapy
  • [MeSH-minor] Female. Gastrointestinal Hemorrhage / diagnosis. Gastrointestinal Hemorrhage / etiology. Gastrointestinal Hemorrhage / therapy. Humans. Injections. Male. Middle Aged. Treatment Outcome

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  • (PMID = 21152456.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 3K9958V90M / Ethanol
  • [Other-IDs] NLM/ PMC2948761
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24. Casseres YA, Mannaerts GH: [Diagnostic image (289). A woman with the sensation that an internal air bubble comes up]. Ned Tijdschr Geneeskd; 2006 Sep 2;150(35):1929
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • She was suffering from a gastric leiomyoma in the cardia-fundus area, which was removed laparoscopically.
  • [MeSH-major] Leiomyoma / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Gastroscopy. Humans. Treatment Outcome

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  • (PMID = 16999277.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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25. Singaporewalla RM, Baladas GH, Lee TD: Laparoendoscopic removal of a benign gastric stromal tumor at the cardia. JSLS; 2006 Jan-Mar;10(1):117-21
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  • [Title] Laparoendoscopic removal of a benign gastric stromal tumor at the cardia.
  • OBJECTIVE: Gastrointestinal stromal tumors are the most common submucosal masses in the stomach and are mostly benign.
  • Tumors close to the cardia often require a stapled resection of stomach.
  • We report a technique for enucleating a 4-cm, well-circumscribed gastric submucosal tumor at the cardia, avoiding gastric transection.
  • METHODS: A gastroscope was introduced to distend the stomach.
  • Two 5-mm metal trocars were inserted into the stomach under vision.
  • A 10-mm trocar was passed through the umbilical incision into the stomach for the camera.
  • The submucosal defect and gastric port-site defects were sutured laparoscopically with Vicryl 3-0.
  • Final histology indicated a benign leiomyoma.
  • CONCLUSION: Benign stromal tumors at the cardia can be safely enucleated by this method.
  • This technique is cost-effective as it avoids expensive staplers or self-retaining gastric balloon ports.

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  • [ErratumIn] JSLS. 2006 Oct-Dec;10(4):550. Moiz, Singaporewalla Reyaz [corrected to Singaporewalla, Reyaz Moiz]; Ganesan, Baladas Haridas [corrected to Baladas, Ganesan Haridas]
  • (PMID = 16709375.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015683
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26. Pickhardt PJ, Kim DH, Taylor AJ, Gopal DV, Weber SM, Heise CP: Extracolonic tumors of the gastrointestinal tract detected incidentally at screening CT colonography. Dis Colon Rectum; 2007 Jan;50(1):56-63
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  • Tumor locations included ileum (n = 3), stomach (n = 3), jejunum (n = 2), and appendix (n = 2).
  • Final diagnoses were benign in all cases and included lipoma (n = 3), small-bowel hamartoma (n = 2), appendiceal mucinous cystadenoma (n = 2), gastric leiomyoma (n = 1), small-bowel lymphangioma (n = 1), and gastric fundic gland polyp (n = 1).
  • CONCLUSIONS: Incidental extracolonic tumors of the gastrointestinal tract detected at screening CT colonography were all asymptomatic and benign but often prompted more invasive workup.

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  • (PMID = 17115333.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Sargan I, Motoc A, Vaida MA, Bolintineanu S: Benign gastric tumors. Anatomopathological aspects of the gastric wall. Rev Med Chir Soc Med Nat Iasi; 2007 Oct-Dec;111(4):996-1000
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign gastric tumors. Anatomopathological aspects of the gastric wall.
  • Benign tumours of the stomach are quite rare and are discovered accidentally during routine endoscopy or necroscopy.
  • They represent less than 20 per cent of gastric tumours, and their clinical picture consists in pain, bleeding and antropyloric stenosis.
  • RESULTS: Benign tumoural pathology was present in 73 cases, 43 (58.9%) in women, 30 (42.1%) in men.
  • The material for study consisted in gastric resection pieces and specimens of needle biopsy.
  • In order to establish the histopathological diagnosis and to define the specific type of the damage, the first specimens were stained using morphological methods.
  • [MeSH-major] Biopsy, Needle. Precancerous Conditions / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma / pathology. Adult. Aged. Aged, 80 and over. Cardia / pathology. Diagnosis, Differential. Female. Hemangioma / pathology. Hospitals, General. Humans. Leiomyoma / pathology. Male. Middle Aged. Neurilemmoma / pathology. Polyps / pathology. Pyloric Antrum / pathology. Retrospective Studies. Treatment Outcome

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  • (PMID = 18389794.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Romania
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28. Prenzel KL, Schäfer E, Stippel D, Beckurts KT, Hölscher AH: Multiple giant leiomyomas of the esophagus and stomach. Dis Esophagus; 2006;19(6):504-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple giant leiomyomas of the esophagus and stomach.
  • Leiomyomas are rare esophageal disorders, although among the benign esophageal neoplasms, they are the most common.
  • Multiple leiomyomas are distinguished from esophageal leiomyomatosis, an extremely rare condition, which is associated with Alport syndrome, showing deletions and rearrangements of the COL4A5/COL4A6 gene.
  • Barium swallow demonstrated narrowing of the middle and lower esophagus with the upper third of the stomach filled by the tumor.
  • The infiltration reached the whole lesser curvature of the stomach.
  • Due to the extended tumor growth with infiltration of the upper third of the stomach, a total esophago-gastrectomy with reconstruction by colon interposition was performed.
  • On histopathological examination multiple esophageal leiomyomas with infiltration of the proximal third of the stomach was shown.
  • If the proximal third of the stomach is infiltrated by the tumor an extended resection is necessary.

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  • (PMID = 17069596.001).
  • [ISSN] 1120-8694
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / COL4A5 protein, human; 0 / Collagen Type IV
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29. Schildhaus HU, Merkelbach-Bruse S, Binot E, Büttner R, Wardelmann E: [Inflammatory fibroid polyp: from Vanek's "submucosal granuloma" to the concept of submucosal mesenchymal neoplasia]. Pathologe; 2010 Mar;31(2):109-14
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  • IFP represent polypous proliferations of spindle cells in the submucosa and mucosa of the stomach, small bowel and colon with inflammatory infiltration.
  • Therefore, IFP represent true benign mesenchymal tumors of the gastrointestinal tract.
  • [MeSH-major] Eosinophilic Granuloma / pathology. Gastrointestinal Neoplasms / pathology. Leiomyoma / pathology. Polyps / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / genetics. Cell Transformation, Neoplastic / genetics. Cell Transformation, Neoplastic / pathology. DNA Mutational Analysis. Diagnosis, Differential. Gastric Mucosa / pathology. Gastritis / pathology. Gastrointestinal Stromal Tumors / genetics. Gastrointestinal Stromal Tumors / pathology. Helicobacter Infections / genetics. Helicobacter Infections / pathology. Helicobacter pylori. Humans. Intestinal Mucosa / pathology. Receptor, Platelet-Derived Growth Factor alpha / genetics. Sequence Analysis, DNA. Sequence Analysis, Protein

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  • (PMID = 20107807.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
  • [Number-of-references] 23
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30. Golubović G, Celeketić D, Kiurski M, Tomasević R, Stanković D, Pavlović A: [Leiomyomas and massive digestive hemorrhages--case reports of patients diagnosed in 2004]. Med Pregl; 2007 May-Jun;60(5-6):292-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Leiomyomas and massive digestive hemorrhages--case reports of patients diagnosed in 2004].
  • INTRODUCTION: During 2004, there were 6 patients with leiomyomas diagnosed and treated at the Department of Gastroenterology and Clinical Pathology of the Zemun Clinical Center.
  • The most common location of these benign submucosal tumors is stomach, followed by small intestine and large intestine.
  • A significant contribution in reaching the final diagnosis and selecting appropriate therapeutic approach was provided by CT and arteriography.
  • Most patients underwent surgical treatment, which provided precise diagnosis (based on histopathologicalfindings), and at the same time a definite therapeutic procedure.
  • DISCUSSION AND CONCLUSION: According to the literature data, gastrointestinal leiomyomas account for 20%-30% of all types of gastrointestinal tumors.
  • Our research revealed that the incidence of leiomyomas was significantly lower within our group of patients, accounting for 12% of all benign gastrointestinal tumors.
  • Presently, endoscopic ultrasonography is considered to be the the most accurate procedure in the diagnosis of leiomyoma, with a diagnostic specificity that is superior to other imaging techniques.
  • [MeSH-major] Gastrointestinal Hemorrhage / etiology. Gastrointestinal Neoplasms / complications. Leiomyoma / complications

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  • (PMID = 17988066.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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31. Starkov IuG, Strekalovskiĭ VP, Shishin KV, Solodinina EN, Domarev LV, Shchegolev AI, Paklina OI: [Laparoscopic transgastric removal of a benign tumor of the stomach]. Khirurgiia (Mosk); 2005;(4):73-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Laparoscopic transgastric removal of a benign tumor of the stomach].
  • [MeSH-major] Laparoscopy. Leiomyoma, Epithelioid / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Follow-Up Studies. Humans. Male. Middle Aged. Stomach / pathology. Time Factors

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  • (PMID = 15943015.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Russia (Federation)
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