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1. Miyazaki T, Yamasaki T, Moritake K, Matsumoto Y, Akiyama Y, Nagai H, Yamamoto Y, Kodama T: Unusual progression of pleomorphic adenoma of the lacrimal gland: case report. Neurol Med Chir (Tokyo); 2005 Aug;45(8):407-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The preoperative diagnosis was pleomorphic adenoma with or without malignant transformation, or cavernous angioma.
  • En bloc excision including adjacent tissues was planned to resolve the progressive symptoms and to obtain a histological diagnosis.
  • The histological diagnosis was pleomorphic adenoma.
  • Accurate clinical diagnosis of neoplasm in the orbital cavity is important for correct therapeutic management.
  • The present case suggests that pleomorphic adenoma should also be considered in the differential diagnosis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Lacrimal Apparatus / pathology. Lacrimal Apparatus Diseases / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Aged. Disease Progression. Exophthalmos / etiology. Exophthalmos / pathology. Exophthalmos / radiography. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Orbit / pathology. Orbit / radiography. Orbit / surgery. Pain / etiology. Pain / pathology. Pain / radiography. Retrobulbar Hemorrhage / etiology. Retrobulbar Hemorrhage / pathology. Retrobulbar Hemorrhage / radiography. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16127259.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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2. Abo-Khatwa MM, Abouel-Enin S, Klimach O, Osborne J: Use of a rectal snare to remove a hypopharyngeal haemangioma. J Laryngol Otol; 2007 Feb;121(2):179-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of a rectal snare to remove a hypopharyngeal haemangioma.
  • We describe in this case report a new technique for treatment of hypopharyngeal haemangioma, using the surgical diathermy snare.
  • We also discuss the histological types of haemangioma, clinical picture, radiological findings and other modalities of treatment.
  • [MeSH-major] Electrocoagulation / instrumentation. Hemangioma / surgery. Hypopharyngeal Neoplasms / surgery

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  • (PMID = 17112397.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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3. Thangappan A, Shields CL, Dinowitz M, Shields JA: Iris cavernous hemangioma associated with multiple cavernous hemangiomas in the kidney, brain, and skin. Cornea; 2007 May;26(4):481-3
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  • [Title] Iris cavernous hemangioma associated with multiple cavernous hemangiomas in the kidney, brain, and skin.
  • PURPOSE: To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child.
  • METHODS: A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris.
  • She had undergone 6 previous brain surgeries and multiple revisions of a ventriculoperitoneal shunt for hydrocephalus beginning at age 3 months.
  • The diagnosis was iris cavernous hemangioma in a patient with multiorgan cavernous hemangiomatosis.
  • By 1-year follow-up, the iris hemangioma deflated, leaving a fibrotic, involuted scar.
  • CONCLUSIONS: Iris cavernous hemangioma can be associated with multiorgan hemangiomas that can be life threatening.
  • [MeSH-major] Brain Neoplasms / pathology. Hemangioma, Cavernous / pathology. Iris Neoplasms / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology


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4. Ooi KG, Wenderoth JD, Francis IC, Wilcsek GA: Selective embolization and resection of a large noninvoluting congenital hemangioma of the lower eyelid. Ophthal Plast Reconstr Surg; 2009 Mar-Apr;25(2):111-4
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  • [Title] Selective embolization and resection of a large noninvoluting congenital hemangioma of the lower eyelid.
  • PURPOSE: To present a combined interventional radiologic and resection technique for the management of a large amblyogenic, highly vascular lesion of the lower eyelid associated with severe mechanical ectropion, conjunctival pyogenic granuloma, and recurrent, spontaneous conjunctival bleeding.
  • Pathology indicated a noninvoluting congenital hemangioma.
  • CONCLUSIONS: To the authors' knowledge, this is the first surgical technique reported in the ophthalmic literature for the selective embolization of a noninvoluting congenital hemangioma prior to its resection.
  • [MeSH-major] Embolization, Therapeutic. Eyelid Neoplasms / congenital. Eyelid Neoplasms / surgery. Hemangioma / congenital. Hemangioma / surgery. Preoperative Care

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  • (PMID = 19300152.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Rudy SJ: Pediatric dermatology: fungal/yeast infections, viral infections, acne, and hemangiomas. Dermatol Nurs; 2007 Oct;19(5):507-8
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  • [Title] Pediatric dermatology: fungal/yeast infections, viral infections, acne, and hemangiomas.

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  • (PMID = 18286865.001).
  • [ISSN] 1060-3441
  • [Journal-full-title] Dermatology nursing
  • [ISO-abbreviation] Dermatol Nurs
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Singh AD, Rundle PA, Vardy SJ, Rennie IG: Photodynamic therapy of choroidal haemangioma associated with Sturge-Weber syndrome. Eye (Lond); 2005 Mar;19(3):365-7
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  • [Title] Photodynamic therapy of choroidal haemangioma associated with Sturge-Weber syndrome.
  • [MeSH-major] Choroid Neoplasms / drug therapy. Hemangioma / drug therapy. Photochemotherapy / methods. Pregnancy Complications, Neoplastic / drug therapy. Sturge-Weber Syndrome / drug therapy


7. Adouani A, Bouguila J, Abdelali MA, Ben Aicha M, Landolsi A, Hellali M, Zitouni K, Mahri I, Zairi I: [Place of the precocious surgical treatment in facial hemangioma]. Ann Chir Plast Esthet; 2008 Oct;53(5):435-40
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  • [Title] [Place of the precocious surgical treatment in facial hemangioma].
  • [Transliterated title] Place du traitement chirurgical précoce dans les hémangiomes périorificiels de la face.
  • Infantile cutaneous hemangioma is a benign vascular tumour present at 10% of the infants.
  • It forms part of the group of the vascular tumours in the classification of international society for vascular anomalies (ISSVA).
  • We insist on the fact that the dogma of the therapeutic abstention remained true for a majority of children with small size hemangioma and that a precocious surgery must be proposed for some localizations in the face.
  • [MeSH-major] Facial Neoplasms / surgery. Hemangioma / surgery

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  • (PMID = 18054819.001).
  • [ISSN] 1768-319X
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 26
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8. O TM, Tan M, Tarango M, Fink L, Mihm M, Ma Y, Waner M: Differential expression of SKI oncogene protein in hemangiomas. Otolaryngol Head Neck Surg; 2009 Aug;141(2):213-8
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  • [Title] Differential expression of SKI oncogene protein in hemangiomas.
  • OBJECTIVE: The pathogenesis for benign tumorigenesis in hemangiomas is unknown.
  • We investigated the differential expression of the SKI (sarcoma viral oncogene) protein in hemangiomas.
  • SUBJECTS AND METHODS: Paraffin-embedded hemangioma tissues were obtained from the senior author from 2005 to 2006.
  • We created the first vascular tissue array composed of 12 hemangioma specimens at various stages of growth and anatomic location.
  • RESULTS: All 12 hemangioma tissues overexpressed the SKI protein.
  • CONCLUSION: SKI oncogene protein is differentially and specifically expressed in hemangioma tissues.
  • CLINICAL SIGNIFICANCE OF STUDY: The SKI oncogene protein is upregulated by hemangiomas and may play a role in hemangioma tumorigenesis.
  • [MeSH-major] Biomarkers, Tumor / analysis. DNA-Binding Proteins / analysis. Hemangioma / chemistry. Hemangioma / diagnosis. Proto-Oncogene Proteins / analysis

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  • (PMID = 19643254.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Proto-Oncogene Proteins; 126648-96-2 / SKI protein, human
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9. Garzon MC, Huang JT, Enjolras O, Frieden IJ: Vascular malformations. Part II: associated syndromes. J Am Acad Dermatol; 2007 Apr;56(4):541-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These lesions occur much less commonly but are often confused with the common infantile hemangioma.
  • Vascular malformations may be associated with underlying disease or systemic anomalies.
  • LEARNING OBJECTIVE: At the completion of this learning activity, participants should be able to better recognize underlying diseases or systemic anomalies that may be associated with vascular malformations.
  • [MeSH-major] Arteriovenous Malformations / diagnosis. Arteriovenous Malformations / therapy. Vascular Diseases / congenital
  • [MeSH-minor] Arteries / abnormalities. Capillaries / abnormalities. Female. Humans. Incidence. Klippel-Trenaunay-Weber Syndrome / diagnosis. Klippel-Trenaunay-Weber Syndrome / epidemiology. Klippel-Trenaunay-Weber Syndrome / therapy. Male. Neurocutaneous Syndromes / diagnosis. Neurocutaneous Syndromes / epidemiology. Neurocutaneous Syndromes / therapy. Prognosis. Risk Assessment. Sturge-Weber Syndrome / diagnosis. Sturge-Weber Syndrome / epidemiology. Sturge-Weber Syndrome / therapy. Veins / abnormalities


10. Erkek E, Hizel S, Sanlý C, Erkek AB, Tombakoglu M, Bozdogan O, Ulkatan S, Akarsu C: Clinical and histopathological findings in Bannayan-Riley-Ruvalcaba syndrome. J Am Acad Dermatol; 2005 Oct;53(4):639-43
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  • We present a case of Bannayan-Riley-Ruvalcaba syndrome with macrocephaly, abnormal facies, lipoma, tender and painful arteriovenous hemangiomas, lymphangiokeratomas, musculoskeletal abnormalities, and localized myopathy.
  • [MeSH-major] Abnormalities, Multiple. Adenomatous Polyposis Coli. Head / abnormalities. Hemangioma. Lentigo
  • [MeSH-minor] Child. Dermis / pathology. Germ-Line Mutation. Humans. Keratosis / pathology. Male. PTEN Phosphohydrolase / genetics. Penile Diseases / pathology. Syndrome. Warts / pathology


11. Ramia JM, Muffak K, Villar J, Garrote D, Ferrón JA: [Benign solid liver tumors]. Cir Esp; 2005 May;77(5):247-53
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  • [Title] [Benign solid liver tumors].
  • Benign solid liver tumors are a heterogeneous group of lesions (adenoma, focal nodular hyperplasia, hemangioma, etc.) with highly varied epidemiological characteristics.
  • Advances in diagnostic methods have improved preoperative diagnosis.
  • Magnetic resonance imaging has become the key test, but there is still a percentage of cases in which definitive preoperative diagnosis is not feasible.
  • Surgery is indicated when diagnosis is uncertain or there are complications (rupture, hemorrhage, etc.).
  • Morbidity and mortality after resection of these tumors is very low since excision is limited, performed in young people without concomitant disease, and in healthy liver.
  • [MeSH-major] Adenoma. Hemangioma, Cavernous. Liver Neoplasms

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  • (PMID = 16420928.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 57
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12. Perumal V, Francisco CJ: Arteriovenous hemangioma of the foot--a case report. Foot Ankle Surg; 2010 Sep;16(3):e61-2
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  • [Title] Arteriovenous hemangioma of the foot--a case report.
  • We report a case of a 40-year-old woman who presented with a heel mass on her left foot.
  • She underwent removal of the mass, which was found to be an arteriovenous hemangioma (AVH).
  • Arteriovenous hemangioma is a rare tumours, especially in the foot which is extremely rare.
  • This tumour should be considered in the differential diagnosis of a mass presenting in the foot.
  • [MeSH-major] Hemangioma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Heel. Humans. Magnetic Resonance Imaging

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  • [Copyright] Copyright (c) 2010 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20655002.001).
  • [ISSN] 1460-9584
  • [Journal-full-title] Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
  • [ISO-abbreviation] Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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13. Juszkat R, Zabicki B, Checiński P, Gabriel M, Matar N: Endovascular treatment of arteriovenous malformation. Aesthetic Plast Surg; 2009 Jul;33(4):639-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • According to the approved classification of vascular lesions by Glowacki and Mulliken, hemangiomas and vascular malformations are distinguishable.
  • Hemangiomas usually appear during the first days or weeks after birth and grow faster than the whole body of the infant.
  • They are proliferating benign tumors that often involute.
  • The opposite of hemangiomas, vascular malformations are present at birth, grow commensurately with the patient, demonstrate normal endothelial turnover, and never involute.
  • The case of a young woman with an arteriovenous malformation (AVM) located on the left side of her face beneath the lower lip is described.

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  • (PMID = 18820964.001).
  • [ISSN] 1432-5241
  • [Journal-full-title] Aesthetic plastic surgery
  • [ISO-abbreviation] Aesthetic Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Skalicky T, Treska V, Sutnar A, Liska V, Mirka H, Ohlidalova K, Ferda J: Surgical treatment of benign liver tumors. Bratisl Lek Listy; 2005;106(10):330-2
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  • [Title] Surgical treatment of benign liver tumors.
  • In their report, the authors evaluated in their report a group of patients with benign liver tumors.
  • In the group of 24 patients with liver haemangioma, the authors recorded 14 patients with focal nodular hyperplasia, 3 patients with hepatocellular adenoma and 2 patients with other types of benign tumors--multilocular cystic lymphangioma of the liver and one hamartoma.
  • [MeSH-minor] Focal Nodular Hyperplasia / surgery. Hemangioma / surgery. Humans

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  • (PMID = 16541615.001).
  • [ISSN] 0006-9248
  • [Journal-full-title] Bratislavské lekárske listy
  • [ISO-abbreviation] Bratisl Lek Listy
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
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15. Opocher G, Schiavi F: Genetics of pheochromocytomas and paragangliomas. Best Pract Res Clin Endocrinol Metab; 2010 Dec;24(6):943-56
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  • The best known hereditary forms of pheochromocytoma and paraganglioma are the von Hippel-Lindau disease, in which pheochromocytoma may be associated with CNS hemangioblastoma, retinal angioma, pancreatic endocrine tumor/cysts and renal clear cell carcinoma/cysts; the multiple endocrine neoplasia type 2, in which pheochromocytoma is associated with medullary thyroid carcinoma and primary hyperparathyroidism, Type 1 neurofibromatosis, the most frequent hereditary cancer syndrome.


16. Prasanna PM, Fredericks SE, Winn SS, Christman RA: Best cases from the AFIP: giant cavernous hemangioma. Radiographics; 2010 Jul-Aug;30(4):1139-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Best cases from the AFIP: giant cavernous hemangioma.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Liver Neoplasms / diagnosis. Magnetic Resonance Angiography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 20631374.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Herman TE, Siegel MJ: Congenital enormous high flow capillary hemangioma of forearm. J Perinatol; 2008 Mar;28(3):235-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital enormous high flow capillary hemangioma of forearm.
  • [MeSH-major] Forearm / abnormalities. Hemangioma, Capillary / blood supply. Magnetic Resonance Angiography

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  • (PMID = 18309319.001).
  • [ISSN] 0743-8346
  • [Journal-full-title] Journal of perinatology : official journal of the California Perinatal Association
  • [ISO-abbreviation] J Perinatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Hudgens JL, Fleet SL, Davis LS: Purpuric nodule on the shoulder. Targetoid hemosiderotic hemangioma. Arch Dermatol; 2006 Oct;142(10):1351-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Purpuric nodule on the shoulder. Targetoid hemosiderotic hemangioma.
  • [MeSH-major] Hemangioma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Hemosiderin / metabolism. Humans. Male. Shoulder

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  • (PMID = 17043193.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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19. Kleiter M, Velde K, Hainisch E, Auer U, Reifinger M: Radiation therapy communication: equine hemangioma. Vet Radiol Ultrasound; 2009 Sep-Oct;50(5):560-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiation therapy communication: equine hemangioma.
  • A 13-month-old Standardbred Colt had a recurrent hemangioma at the level of the coronary band.
  • [MeSH-major] Hemangioma / veterinary. Hindlimb. Horse Diseases / radiotherapy. Radiotherapy, High-Energy / veterinary. Skin Neoplasms / veterinary

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  • (PMID = 19788045.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Popescu I, Vasile S, Sgarbură O, Hrehoreţ D, Tomulescu V: [Laparoscopic left lateral segmentectomy of the liver: indications, technique, results]. Chirurgia (Bucur); 2008 Jan-Feb;103(1):17-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: The laparoscopic approach of the hepatic lesions located in the left lobe is a frequently used procedure in liver surgery for both benign and malign tumors because of the minimal invasive character, anatomical particularities and modem devices used in hemostasis and biliary-stasis.
  • The hepatic lesions approached laparoscopically were both benign (5 cases out of which 3 hemangioma and 2 adenoma) and malignant (7 cases hepatocellular carcinoma).
  • [MeSH-minor] Adenoma / surgery. Aged. Carcinoma, Hepatocellular / surgery. Cohort Studies. Digestive System Surgical Procedures / methods. Female. Hemangioma / surgery. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18459493.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
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21. Bouguila J, Yacoub K, Bouguila H, Neji NB, Sahtout S, Besbes G: [Intraorbital cavernous hemangioma]. Rev Stomatol Chir Maxillofac; 2008 Nov;109(5):312-5
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  • [Title] [Intraorbital cavernous hemangioma].
  • Cavernous hemangioma is the most frequent primary vascular orbital tumor in adults.
  • [MeSH-major] Hemangioma, Cavernous / surgery. Orbital Neoplasms / surgery

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  • (PMID = 18707746.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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22. Erdemoglu E, Kamaci M, Ozen S, Sahin HG, Kolusari A: Ovarian hemangioma with elevated CA125 and ascites mimicking ovarian cancer. Eur J Gynaecol Oncol; 2006;27(2):195-6
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  • [Title] Ovarian hemangioma with elevated CA125 and ascites mimicking ovarian cancer.
  • We report a case of a very rare tumor of the ovary with an unusual presentation; an ovarian hemangioma with massive ascites and elevated CA125.
  • Pathologic examination revealed cavernous hemangioma which is an extremely rare tumor of the ovary.
  • Although it is very unusual, an ovarian hemangioma may present with ascites and elevated CA125 and the differential diagnosis from ovarian cancer should be considered.
  • [MeSH-major] Ascites / etiology. CA-125 Antigen / blood. Hemangioma / complications. Hemangioma / surgery. Ovarian Neoplasms / complications. Ovarian Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Laparotomy. Middle Aged


23. Mundinger GS, Gust S, Micchelli ST, Fishman EK, Hruban RH, Wolfgang CL: Adult pancreatic hemangioma: case report and literature review. Gastroenterol Res Pract; 2009;2009:839730
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  • [Title] Adult pancreatic hemangioma: case report and literature review.
  • We report an adult pancreatic hemangioma diagnosed on pathological specimen review following pylorus preserving pancreaticoduodenectomy for a symptomatic cystic mass in the head of the pancreas.
  • Eight cases of adult pancreatic hemangioma have been reported in literature since 1939.
  • Presenting symptoms, radiographic diagnosis, pathologic characteristics, and treatment of adult pancreatic hemagiomas are discussed following review of all published cases.

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  • [Cites] JOP. 2006;7(5):496-501 [16998249.001]
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  • (PMID = 19421421.001).
  • [ISSN] 1687-630X
  • [Journal-full-title] Gastroenterology research and practice
  • [ISO-abbreviation] Gastroenterol Res Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2676326
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24. Akiyama T, Hamazaki S, Monobe Y, Nishimura H, Irei I, Sadahira Y: Sphingosine-1-phosphate receptor 1 is a useful adjunct for distinguishing vascular neoplasms from morphological mimics. Virchows Arch; 2009 Feb;454(2):217-22
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  • S1P(1) expression was observed in eight of eight hemangiomas, four of four lymphangiomas, four of four epithelioid hemangioendotheliomas, three of three Kaposi's sarcomas, and 15 of 15 angiosarcomas with vasoformative, spindle, epithelioid, and undifferentiated features.
  • Conventional analysis and use of a tissue microarray of soft tissue tumors revealed three of 21 liposarcomas to have weak cytoplasmic staining and one of five squamous cell carcinomas to have membranous staining in a very limited area among 115 nonvascular tumors including histological mimics of angiosarcoma such as undifferentiated carcinoma, melanoma, and epithelioid sarcoma.
  • Based on this study, S1P(1) may be a useful adjunct to CD31 in cases where a vascular neoplasm requires a differential diagnosis.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasms, Vascular Tissue / diagnosis. Receptors, Lysosphingolipid / analysis
  • [MeSH-minor] Adult. Aged. Female. Hemangioma / diagnosis. Hemangiosarcoma / diagnosis. Humans. Immunohistochemistry. Lymphangioma / diagnosis. Male. Middle Aged

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  • (PMID = 19005676.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Lysosphingolipid
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25. Kawano Y, Tamura A, Goto Y, Shinozaki K, Zaizen H, Kadota J: Incidental detection of cancers and other non-cardiac abnormalities on coronary multislice computed tomography. Am J Cardiol; 2007 Jun 1;99(11):1608-9
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  • [Title] Incidental detection of cancers and other non-cardiac abnormalities on coronary multislice computed tomography.
  • The investigators prospectively examined 625 consecutive patients who underwent coronary multislice computed tomography (MSCT) for suspected coronary artery disease (CAD) and evaluated the presence or absence of cancers and other noncardiac abnormalities on the original transverse sectional images of MSCT.
  • In addition, nonmalignant abnormalities (nodules, tumors, or lymphadenopathies) were also found in 142 patients (23.01%), consisting of 58 postinflammatory lung nodules (9.40%), 49 hepatic cysts or hemangiomas (7.94%), 18 benign thyroid tumors (2.92%), 12 mediastinal lymphadenopathies (1.94%), 4 benign mammary gland tumors (0.65%), and 1 esophageal submucosal tumor (0.16%).
  • [MeSH-major] Coronary Artery Disease / radiography. Incidental Findings. Neoplasms / pathology. Neoplasms / radiography. Tomography, X-Ray Computed


26. Vogel AM, Alesbury JM, Burrows PE, Fishman SJ: Vascular anomalies of the female external genitalia. J Pediatr Surg; 2006 May;41(5):993-9
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  • METHODS: An international review board-approved retrospective database and a record review from 1994 through 2004 was conducted.
  • Tumors included 20 infantile hemangiomas, 1 kaposiform hemangioendothelioma, and 1 kaposiform lymphangioendothelioma.
  • The referring diagnosis was incorrect in 56% of patients.
  • CONCLUSIONS: Vascular anomalies of the female external genitalia are uncommon, and the initial diagnosis is often inaccurate.
  • Correct diagnosis using clinical and radiographic data is feasible and leads to meaningful intervention for these frequently devastating lesions.

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  • (PMID = 16677899.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Kawatra V, Lakshmikantha A, Dhingra KK, Gupta P, Khurana N: A rare coexistence of concurrent breast hemangioma with fibroadenoma: a case report. Cases J; 2009;2:7005
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  • [Title] A rare coexistence of concurrent breast hemangioma with fibroadenoma: a case report.
  • We report the case of a 38-year-old Asian, Indian female with capillary hemangioma breast in coexistence with the commonly occurring fibroadenoma.
  • Histopathology confirmed the diagnosis of a completely encapsulated fibroadenoma coexistent with a capillary hemangioma in the adjacent breast tissue.
  • The rarity of literature on breast hemangioma especially capillary type with coexisting fibroadenoma deserves mention.

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  • (PMID = 19829893.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2740063
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28. Torres-Carranza E, García-Perla A, Infante-Cossío P, Acosta-Feria M, Belmonte-Caro R, Gutiérrez-Pérez JL: [Primary intraosseous hemangioma of the orbit: report of two cases]. Neurocirugia (Astur); 2007 Aug;18(4):320-5
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  • [Title] [Primary intraosseous hemangioma of the orbit: report of two cases].
  • [Transliterated title] Hemangioma intraóseo primario de la órbita: a propósito de dos casos.
  • Primary intraosseous hemangioma, though rarely affect the bones of the orbit, should be considered in the differential diagnosis when a patient presents an enlarging mass fixed to the bone in the orbit or signs of progressive painless proptosis.
  • Assessing the exact site and extent of the hemangioma by means of a CT scan and MRI and establishing the vascular origin of the lesion, is critical in the therapeutical planning, since an inadequate management may result in a severe hemorrhage.
  • Two cases of patients with primary intraosseus hemangioma of the supra-lateral orbital rim are reported.
  • After three-year follow-up there have not been evidence of local recurrence, and the functional and aesthetic results obtained have been very satisfactory.
  • [MeSH-major] Hemangioma / pathology. Orbit / pathology. Orbital Neoplasms / pathology

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  • (PMID = 17882339.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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29. Simadibrata M, Abdullah M: Rectal hemangioma. Acta Med Indones; 2006 Jul-Sep;38(3):167-8
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  • [Title] Rectal hemangioma.
  • [MeSH-major] Hemangioma / diagnosis. Rectal Neoplasms / diagnosis

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  • (PMID = 16953034.001).
  • [ISSN] 0125-9326
  • [Journal-full-title] Acta medica Indonesiana
  • [ISO-abbreviation] Acta Med Indones
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Indonesia
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30. Bartolotta TV, Sandonato L, Taibbi A, Latteri S, Soresi M, Lombardo G, Genova C, Latteri MA: [Focal liver lesions: clinical usefulness of contrast-enhanced ultrasound in the selection of surgical patients]. Chir Ital; 2009 May-Jun;61(3):295-307
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  • [Transliterated title] Lesioni focali epatiche: utilità clinica dell'ecografia con mezzo di contrasto nella selezione delpaziente chirurgico.
  • One hundred and thirty-five consecutive patients (71 women, 64 men) with 165 focal liver lesions (mean size: 3.1 cm)--89 benign (10 simple cysts, 26 haemangiomas, 29 focal nodular hyperplasia, 2 hepatocellular adenomas, 11 focal fatty sparing, 3 focal fatty areas, 5 regenerative nodules, 2 hydatid cysts, 1 abscess) and 76 malignant (47 metastases, 26 hepatocellular carcinomas and 3 peripheral cholangiocarcinomas)--underwent CEUS after the administration of SonoVue.
  • The radiologists classified each lesion as malignant or benign on the basis of clearly defined diagnostic criteria.
  • CEUS correctly characterised 156/165 focal liver lesions (94.5%), 85 benign and 71 malignant.
  • Five focal liver lesions (3%; 3 haemangiomas and 2 hepatocellular carcinomas) remained undetermined after CEUS and 4 focal liver lesions (2.4%; 3 hepatocellular carcinomas and 1 abscess) were misdiagnosed.
  • [MeSH-major] Contrast Media. Liver Diseases / surgery. Liver Diseases / ultrasonography. Patient Selection. Ultrasonography, Doppler, Color / methods
  • [MeSH-minor] Adenoma, Liver Cell / surgery. Adenoma, Liver Cell / ultrasonography. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / surgery. Carcinoma / ultrasonography. Cholangiocarcinoma / surgery. Cholangiocarcinoma / ultrasonography. Cysts / surgery. Cysts / ultrasonography. Diagnosis, Differential. Echinococcosis, Hepatic / surgery. Echinococcosis, Hepatic / ultrasonography. Fatty Liver / surgery. Fatty Liver / ultrasonography. Female. Focal Nodular Hyperplasia / surgery. Focal Nodular Hyperplasia / ultrasonography. Hemangioma / surgery. Hemangioma / ultrasonography. Humans. Liver Neoplasms / surgery. Liver Neoplasms / ultrasonography. Male. Middle Aged. Predictive Value of Tests. Retrospective Studies. Sensitivity and Specificity. Treatment Outcome. Ultrasonography, Interventional / methods

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  • (PMID = 19694231.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contrast Media
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31. Trillaud H, Bruel JM, Valette PJ, Vilgrain V, Schmutz G, Oyen R, Jakubowski W, Danes J, Valek V, Greis C: Characterization of focal liver lesions with SonoVue-enhanced sonography: international multicenter-study in comparison to CT and MRI. World J Gastroenterol; 2009 Aug 14;15(30):3748-56
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  • [Title] Characterization of focal liver lesions with SonoVue-enhanced sonography: international multicenter-study in comparison to CT and MRI.
  • The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined.
  • The final diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used.
  • RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions.
  • The sensitivity and specificity of CEUS for the identification of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%.
  • [MeSH-major] Focal Nodular Hyperplasia. Hemangioma. Liver. Liver Neoplasms. Magnetic Resonance Imaging. Tomography, X-Ray Computed. Ultrasonography


32. Iba Y, Watanabe S, Akimoto T, Abe K, Koyanagi H: Pedicled cardiac hemangioma with right ventricular outflow tract obstruction. Jpn J Thorac Cardiovasc Surg; 2005 May;53(5):269-71
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  • [Title] Pedicled cardiac hemangioma with right ventricular outflow tract obstruction.
  • Histological examination revealed the nature of the tumor to be a benign hemangioma.
  • As reports of cardiac hemangioma causing severe RVOT obstruction are extremely rare, this case warrants attention.
  • [MeSH-major] Heart Neoplasms / complications. Hemangioma / complications. Ventricular Outflow Obstruction / etiology

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  • (PMID = 15952321.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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33. Xu HX, Liu GJ, Lu MD, Xie XY, Xu ZF, Zheng YL, Liang JY: Characterization of small focal liver lesions using real-time contrast-enhanced sonography: diagnostic performance analysis in 200 patients. J Ultrasound Med; 2006 Mar;25(3):349-61
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  • A 5-point confidence level was used to discriminate malignant from benign FLLs, and specific diagnoses were recorded.
  • RESULTS: After review of contrast-enhanced sonography, ROC analysis revealed significant improvement in differentiating between malignant and benign small FLLs that the areas under the ROC curve were 0.856 at baseline sonography versus 0.954 at contrast-enhanced sonography for reader 1 (P < .001) and 0.857 versus 0.954 for reader 2 (P = .003).
  • A better result of specific diagnosis was obtained (38.5% [77/200] at baseline sonography versus 80.5% [161/200] at contrast-enhanced sonography for reader 1 and 34.5% [69/200] versus 80.5% [161/200] for reader 2; both P < .001) after contrast agent administration, and a better interobserver agreement was achieved (kappa = 0.425 at baseline sonography versus 0.716 at contrast-enhanced sonography).
  • [MeSH-major] Carcinoma, Hepatocellular / diagnosis. Contrast Media / administration & dosage. Hemangioma / diagnosis. Image Enhancement / methods. Liver / ultrasonography. Liver Diseases / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Echocardiography, Doppler, Color / methods. Female. Granuloma, Plasma Cell / diagnosis. Humans. Male. Microbubbles. Middle Aged. Observer Variation. Prospective Studies. ROC Curve. Reproducibility of Results. Sensitivity and Specificity. Sulfur Hexafluoride / administration & dosage

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  • (PMID = 16495496.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; WS7LR3I1D6 / Sulfur Hexafluoride
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34. Xu WL, Niu AG, Li SL, Li ZD: [Pingyangmycin emulsion inducing apoptosis in infantile proliferating capillary hemangiomas]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2006 Sep;22(5):362-4
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  • [Title] [Pingyangmycin emulsion inducing apoptosis in infantile proliferating capillary hemangiomas].
  • OBJECTIVE: To insight whether PYM emulsion induces apoptosis more rapidly in proliferating capillary hemangiomas so as to find the optimal method for hemangiomas' treatment.
  • METHODS: Thirty volunteers of infantile proliferating hemangiomas were divided into control group (15 cases) and mediational group (15 cases).
  • CONCLUSIONS: PYM emulsion can effectively accelerate apoptosis in infantile proliferating capillary hemangiomas .
  • [MeSH-major] Apoptosis / drug effects. Bleomycin / analogs & derivatives. Hemangioma, Capillary / pathology

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  • (PMID = 17144454.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 11116-32-8 / bleomycetin
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35. Kornasiewicz O, Debski M, Stepnowska M, Szałas A, Bar-Andziak E, Krawczyk M: The enzymatic activity of type 1 iodothyronine deiodinase (D1) is low in liver hemangioma: a preliminary study. Arch Immunol Ther Exp (Warsz); 2010 Feb;58(1):77-80
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  • [Title] The enzymatic activity of type 1 iodothyronine deiodinase (D1) is low in liver hemangioma: a preliminary study.
  • However, there are few available data about D1 enzyme activity in benign tumors such as hemangioma, which is the most common primary liver tumor.
  • Hence this study aimed to determine the enzymatic activity of D1 in hemangiomas in relation to healthy liver tissue.
  • Seven tumors and healthy control tissues were obtained from patients who had liver resection due to hemangioma.
  • It was found that D1 activity was significantly lower in the hemangiomas than in the healthy surrounding tissue (p = 0.0017).
  • Healthy liver tissue expresses a high level of D1, but disturbed D1 activity may result in changes in the local concentration of T3 which may impair gene transcription.
  • These finding demonstrate a low enzymatic activity of D1 in liver hemangioma and suggest an as yet unknown role of thyroid hormones in this type of benign liver tumor.
  • [MeSH-major] Hemangioma / enzymology. Iodide Peroxidase / metabolism. Liver / enzymology. Liver Neoplasms / enzymology

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  • (PMID = 20049650.001).
  • [ISSN] 1661-4917
  • [Journal-full-title] Archivum immunologiae et therapiae experimentalis
  • [ISO-abbreviation] Arch. Immunol. Ther. Exp. (Warsz.)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] EC 1.11.1.- / iodothyronine deiodinase type I; EC 1.11.1.8 / Iodide Peroxidase
  • [Other-IDs] NLM/ PMC2816262
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36. Hong HS, Kim HS, Kim MJ, De Becker J, Mitchell DG, Kanematsu M: Single breath-hold multiarterial dynamic MRI of the liver at 3T using a 3D fat-suppressed keyhole technique. J Magn Reson Imaging; 2008 Aug;28(2):396-402
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  • The enhancement pattern of each hepatic lesion was analyzed according to the specific diagnosis.
  • The progressive centripetal enhancement of hemangiomas (n = 6) was clearly depicted.
  • [MeSH-major] Image Enhancement / methods. Imaging, Three-Dimensional. Liver Diseases / diagnosis. Magnetic Resonance Imaging / methods

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18666146.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 15G12L5X8K / gadobenic acid; 6HG8UB2MUY / Meglumine
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37. Lowman E, Mooradian AD: Macromelia masquerading as an acromegaloid syndrome in an adult with Klippel-Trénaunay syndrome. Endocr Pract; 2008 Jan-Feb;14(1):109-11
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  • The patient's insulinlike growth factor 1 concentration was 92 ng/mL (reference range, 117-329 ng/mL), which did not support the diagnosis of acromegaly.
  • Classically, the syndrome presents as a triad of vascular malformations, cutaneous hemangiomas, and bone or soft-tissue hypertrophy usually affecting one extremity.
  • [MeSH-major] Acromegaly / diagnosis. Klippel-Trenaunay-Weber Syndrome / diagnosis. Lymphedema / diagnosis. Port-Wine Stain / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Syndrome

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  • (PMID = 18238750.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Yun JP, Miao J, Chen GG, Tian QH, Zhang CQ, Xiang J, Fu J, Lai PB: Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters. Br J Cancer; 2007 Feb 12;96(3):477-84
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  • In this study, we examined NPM expression in 103 paired cases of hepatocellular carcinoma (HCC), 12 cases of hepatic focal nodular hyperplasia, 17 cases of liver tissue adjacent to a hepatic haemangioma, and series of array tissues from normal human organs and malignancies using a monoclonal antibody against NPM and reverse transcription-PCR techniques, Western blot analysis, immunohistochemistry, and immunocytofluorescence.
  • Our data indicated that NPM expression was significantly higher in HCC than in the non-malignant hepatocytes (P<0.001).

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  • (PMID = 17245342.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Proliferating Cell Nuclear Antigen; 117896-08-9 / nucleophosmin
  • [Other-IDs] NLM/ PMC2360035
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39. Lawley LP, Cerimele F, Weiss SW, North P, Cohen C, Kozakewich HP, Mulliken JB, Arbiser JL: Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions. Arch Dermatol; 2005 Oct;141(10):1297-300
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  • BACKGROUND: Vascular malformations and hemangiomas, which are endothelial lesions of childhood, may result in considerable morbidity because they can cause discomfort and functional impairment and have a negative affect on the patient's appearance.
  • Although vascular malformations may initially appear very similar to hemangiomas, they have distinct clinical courses.
  • Infantile hemangiomas progress through 3 stages: proliferative, involuting, and involuted.
  • Once hemangiomas reach their maximum size, they begin to regress or involute.
  • Finally, the involuted stage of the hemangioma occurs when the original lesion is replaced by a connective tissue remnant.
  • In contrast to hemangiomas, vascular malformations do not involute but continue to enlarge as the patient grows.
  • OBSERVATIONS: The biochemical differences between hemangiomas, which involute, and vascular malformations, which do not involute, are not well understood.
  • We found that the transcription factor encoded by the Wilms tumor 1 (WT1) gene is expressed in the endothelium of hemangiomas but not in vascular malformations.
  • The availability of WT1 staining in hospital laboratories may allow the clinician to distinguish hemangiomas from vascular malformations and thus to give appropriate therapy to the patient.
  • [MeSH-major] Arteriovenous Malformations / diagnosis. Arteriovenous Malformations / genetics. Gene Expression. Genes, Wilms Tumor. Hemangioma / diagnosis. Hemangioma / genetics
  • [MeSH-minor] Apoptosis. Diagnosis, Differential. Disease Progression. Humans. Immunohistochemistry

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  • (PMID = 16230568.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / R01 AR47901
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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40. Schaffer JV, Fangman W, Bossenbroek NM, Meehan SA, Kamino H: Tufted angioma. Dermatol Online J; 2008;14(10):20
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  • [Title] Tufted angioma.
  • Histopathologic evaluation showed multiple, discrete lobules of tightly packed capillaries in a 'cannonball' pattern within the dermis, which confirmed the diagnosis of tufted angioma.
  • The clinical and histopathologic features, natural history, and treatment options for tufted angiomas are reviewed; their relationship to kaposiform hemangioendotheliomas is discussed.
  • [MeSH-major] Hemangioma / diagnosis. Skin Neoplasms / diagnosis


41. Gallentine WB, Mikati MA: Intraoperative electrocorticography and cortical stimulation in children. J Clin Neurophysiol; 2009 Apr;26(2):95-108
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  • In children younger than 10 years, cortical stimulation identifies language cortex at a lower rate than in children older than 10 years or in adults. (2) They have variability within the same individual in the stimulation threshold depending on the cortical site.
  • This often results in the need to maximize stimulation of currents at each cortical site regardless of adjacent afterdischarge threshold. (3) They demonstrate more difficultly to evoke motor responses particularly with certain pathologies such as retrorolandic low-grade tumors.
  • These lesions include brain tumors, cortical dysplasia resulting in intractable epilepsy, and cavernous angioma causing epilepsy.

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  • (PMID = 19279495.001).
  • [ISSN] 1537-1603
  • [Journal-full-title] Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • [ISO-abbreviation] J Clin Neurophysiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Intravenous; YI7VU623SF / Propofol
  • [Number-of-references] 87
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42. Gianfrancesco F, Cannella M, Martino T, Maglione V, Esposito T, Innocenzi G, Vitale E, Liquori CL, Marchuk DA, Squitieri F: Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations. Am J Med Genet B Neuropsychiatr Genet; 2007 Jul 5;144B(5):691-5
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  • [Title] Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations.
  • In most cases, cerebral cavernous malformations (CCMs) involve the brain alone, and are rarely associated with skin hemangiomas, spinal cord, retinal, hepatic or vertebral lesions.
  • After collecting CCM families of Italian origin and investigating the genetic basis of the disorder we disclosed two novel molecular variations in the KRIT1 and MGC4607 genes.
  • We found a novel CCM1 gene mutation (Q66X) in a family with apparently asymptomatic old-aged mutation carriers and patients who either had skin angiomas alone or the full association of cerebral, spinal, and skin lesions.
  • [MeSH-major] Carrier Proteins / genetics. Hemangioma, Cavernous, Central Nervous System / genetics. Microtubule-Associated Proteins / genetics. Mutation. Penetrance. Proto-Oncogene Proteins / genetics

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  • (PMID = 17440989.001).
  • [ISSN] 1552-4841
  • [Journal-full-title] American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • [ISO-abbreviation] Am. J. Med. Genet. B Neuropsychiatr. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCM2 protein, human; 0 / Carrier Proteins; 0 / KRIT1 protein, human; 0 / Microtubule-Associated Proteins; 0 / Proto-Oncogene Proteins
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43. Anand N, Rai AK: Nasopharyngeal glioma: A unique presentation in infants. Indian J Otolaryngol Head Neck Surg; 2007 Jun;59(2):151-3
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  • Of the various anomalies like-nasopharyngeal cysts, hairy polyps, dermoids, haemangiomata, fibromas, mucocoeles, lipoma, aplasias.

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  • (PMID = 23120416.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3451793
  • [Keywords] NOTNLM ; Glioma Nasopharynx infants
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44. Buhl R, Barth H, Dörner L, Nabavi A, Rohr A, Mehdorn HM: De novo development of intraosseous cavernous hemangioma. J Clin Neurosci; 2007 Mar;14(3):289-92
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  • [Title] De novo development of intraosseous cavernous hemangioma.
  • Intraosseous cavernous hemangiomas are rare and not often multifocal.
  • De novo development of a skull cavernous hemangioma has not been described previously.
  • We present a 20-year-old man who was operated upon for a skull cavernoma in the right frontal area and developed a new lesion 3 years later in the right occipital region.
  • Histology showed an intraosseous cavernous hemangioma.
  • Surgical removal was performed and histology again showed a cavernous hemangioma.
  • The patient seems to be unique and it is important to keep young patients with the diagnosis of cavernous hemangioma under close follow-up.
  • This supports the experience from parenchymatous cavernous hemangiomas that this malformation may become a dynamic disease.
  • [MeSH-major] Frontal Bone / pathology. Hemangioma, Cavernous / pathology. Neoplasms, Second Primary / pathology. Occipital Bone / pathology. Skull Neoplasms / pathology

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  • (PMID = 17258139.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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45. Huang W, Hu XL, Gao XF, Liu Y, Zhao LS: [Distribution, GLUT-1 expression and early surgical intervention for infantile hemangioma on the face]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2009 Sep;25(5):321-4
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  • [Title] [Distribution, GLUT-1 expression and early surgical intervention for infantile hemangioma on the face].
  • OBJECTIVE: To investigate the development, distribution and GLUT-1 expression of infantile hemangioma and to discuss the early surgical intervention for better results and avoiding severe complication.
  • METHODS: The lesion site of each case was recorded and analyzed by SPSS V13.0 to study the distribution.
  • The operation was guided by the principle of plastic surgery to remove the hemangioma.
  • 71.7% of the hemangiomas were located at upper and lower lip, periorbital region and facial midline.
  • It indicates that hemangioma is not randomly distributed.
  • CONCLUSIONS: Infantile facial hemangioma maybe originated from endothelial progenitor cells of placenta which migrate and implant on the fusion of facial prominences.
  • Early surgical intervention is one of the best choice for infantile facial hemangioma.
  • [MeSH-major] Face / pathology. Glucose Transporter Type 1 / metabolism. Hemangioma / pathology. Hemangioma / surgery

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  • (PMID = 20030103.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glucose Transporter Type 1; 0 / SLC2A1 protein, human
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46. Choi JC, Baek YH, Jeong JS, Lee SW, Han SY, Cho JH: Discrete hypoechoic ring in hepatic cavernous hemangioma resembling a malignant tumor: correlation with histologic features. Gut Liver; 2009 Sep;3(3):226-30
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  • [Title] Discrete hypoechoic ring in hepatic cavernous hemangioma resembling a malignant tumor: correlation with histologic features.
  • Differential diagnoses of hepatic nodules include hepatocellular carcinoma, focal nodular hyperplasia, hepatic adenoma, regenerative nodule, focal fatty changes, and hemangioma.
  • Hemangiomas are frequently encountered during ultrasonogram incidentally and can be diagnosed easily because they have an almost distinctive sonographic appearance: a homogeneous hyperechogenicity and discrete posterior acoustic enhancement.
  • We report herein the case of an atypical hemangioma presenting with a hypoechoic peripheral ring, mimicking a hepatic malignancy.
  • To our knowledge, there have been no other reports demonstrating a cavernous hemangioma with a discrete hypoechoic ring and without a pseudocapsule.

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  • [Cites] Gastrointest Radiol. 1989 Summer;14(3):262-4 [2659425.001]
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  • (PMID = 20431752.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2852708
  • [Keywords] NOTNLM ; Hemangioma / Hepatic malignancy / Hypoechoic ring / Ultrasonography
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47. Fortunato M, Di Pietro R, Gravina L, Maggi R, Ubaldi A, Vadalà P: Photodynamic therapy in von Hippel-Lindau disease in children. J Pediatr Ophthalmol Strabismus; 2009 Nov-Dec;46(6):376-9
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  • [Title] Photodynamic therapy in von Hippel-Lindau disease in children.
  • Von Hippel-Lindau disease is characterized by retinal hemangiomas that often produce hemorrhages and retinal detachment.
  • A 10-year-old boy with von Hippel-Lindau disease presenting with telangiectasias, endophytic angiomas, and exudative retinal detachment underwent treatment with retrobulbar steroid injection, laser photocoagulation, and photodynamic therapy, which led to improvement of visual acuity.
  • [MeSH-major] Photochemotherapy / methods. Photosensitizing Agents / therapeutic use. Porphyrins / therapeutic use. Retinal Detachment / drug therapy. von Hippel-Lindau Disease / drug therapy

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  • [Copyright] Copyright 2009, SLACK Incorporated.
  • (PMID = 19928746.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
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48. Kim SH, Lee JM, Kim KG, Kim JH, Lee JY, Han JK, Choi BI: Computer-aided image analysis of focal hepatic lesions in ultrasonography: preliminary results. Abdom Imaging; 2009 Mar-Apr;34(2):183-91
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  • MATERIALS AND METHODS: Two abdominal radiologists, blinded to the final diagnosis, independently evaluated sonographic images of 51 focal hepatic lesions in 47 patients: hemangiomas (n = 19), hepatic simple cysts or cystic lesions (n = 14), hepatocellular carcinoma (n = 11), metastases (n = 6), and focal fat deposition (n = 1).
  • CONCLUSION: As a preliminary step in US computer-aided diagnosis for focal hepatic lesions, a CAIA algorithm was constructed with a good agreement and correlation with human observers in most US features.
  • In addition, these features should be weighted highly when a computer-aided diagnosis for characterizing focal liver lesions on US is designed and developed.
  • [MeSH-major] Algorithms. Image Processing, Computer-Assisted. Liver Diseases / ultrasonography. Liver Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Aged. Carcinoma, Hepatocellular / ultrasonography. Cysts / ultrasonography. Female. Hemangioma / ultrasonography. Humans. Male. Middle Aged

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  • (PMID = 18386094.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Peker E, Kirimi E, Tuncer O, Ceylan A, Oner AF: Brachial plexus paralysis due to giant cavernous hemangioma with Kasabach-Merritt syndrome: successful management with interferon alpha. Platelets; 2009 Dec;20(8):603-5
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  • [Title] Brachial plexus paralysis due to giant cavernous hemangioma with Kasabach-Merritt syndrome: successful management with interferon alpha.
  • Giant hemangiomas are rare in newborn babies and may cause some life-threatening complications such as congestive heart failure and coagulopathies including severe thrombocytopenia, microangiopathic hemolytic anemia and bleeding such as Kasabach-Merritt syndrome.
  • We have presented here one infant case with a right lower brachial plexus paralysis due to giant hemangioma treated successfully with interferon alpha and have discussed the treatment.
  • The administration of interferon-alpha might be indicated as a therapy for severe, life-threatening and giant hemangiomas such as Kasabach-Merritt syndrome, especially when there is resistance to steroid.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Brachial Plexus Neuropathies. Hemangioma, Cavernous. Interferon-alpha / therapeutic use

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  • (PMID = 19929246.001).
  • [ISSN] 1369-1635
  • [Journal-full-title] Platelets
  • [ISO-abbreviation] Platelets
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Interferon-alpha; 0 / Recombinant Proteins; 76543-88-9 / interferon alfa-2a
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50. Ortonne JP: [What's new in dermatological treatments?]. Ann Dermatol Venereol; 2008 Dec;135 Suppl 7:S360-70
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  • [Transliterated title] Quoi de neuf en thérapeutique dermatologique?
  • However, non randomized studies, even informative clinical cases have been included.
  • Overall, 26 articles have been selected concerning different aspects of therapeutics in dermatology and involving the following disorders : psoriasis, hypereosinophilic syndrome, vulvar neoplasias, melanoma, mycosis fungoides and Sezary syndrome, bullous pemphigoïd, vulvar pemphigus, pyoderma gangrenosum, hemangiomas, acne, atopic dermatitis, sclerodermatous chronic graft-vs-host disease, tuberous sclerosis complex, epidermal necrolysis, hirsutism, vitiligo.
  • [MeSH-major] Dermatologic Agents / therapeutic use. Dermatology / trends. Skin Diseases / drug therapy

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  • (PMID = 19264212.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Dermatologic Agents
  • [Number-of-references] 26
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51. Papageorgiou SG, Kontaxis T, Samara C, Kalfakis N, Vassilopoulos D: Spinal cavernoma: an unusual cause of acute monoparesis. Neurologist; 2009 Sep;15(5):291-2
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  • INTRODUCTION: Cavernous hemangiomas or cavernomas are uncommon vascular malformations of the central nervous system involving most commonly the cerebral hemispheres where they are detected in young to middle aged adults.
  • The initial diagnosis was lacunar stroke, but the brain magnetic resonance imaging revealed a right temporal cavernoma-obviously not associated with her monoparesis.
  • CONCLUSION: Our patient presented with an acute monoparesis because of a spinal cavernoma, a most unusual occurrence.
  • [MeSH-major] Hemangioma, Cavernous, Central Nervous System / complications. Medulla Oblongata. Paresis / etiology. Spinal Cord Diseases / complications
  • [MeSH-minor] Acute Disease. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Functional Laterality. Humans. Magnetic Resonance Imaging. Neurologic Examination. Stroke / diagnosis

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  • (PMID = 19741439.001).
  • [ISSN] 2331-2637
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Tovar JA: Stephen L. Gans Distinguished Overseas Lecture. The neural crest in pediatric surgery. J Pediatr Surg; 2007 Jun;42(6):915-26
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  • METHODS: The participation of the NC in facial clefts, ear defects, branchial fistulae and cysts, heart outflow tract and aortic arch anomalies, pigmentary disorders, abnormal enteric innervation, neural tumors, hemangiomas, and vascular anomalies is briefly reviewed.

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  • (PMID = 17560195.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / GLI1 protein, human; 0 / Hedgehog Proteins; 0 / Homeodomain Proteins; 0 / Receptors, Cell Surface; 0 / Receptors, G-Protein-Coupled; 0 / Receptors, Retinoic Acid; 0 / SHH protein, human; 0 / SMO protein, human; 0 / Transcription Factors; 0 / patched receptors; 5688UTC01R / Tretinoin
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53. Yang SZ, Dong JH, Li K, Zhang Y, Zhu J: Detection of AFPmRNA and melanoma antigen gene-1mRNA as markers of disseminated hepatocellular carcinoma cells in blood. Hepatobiliary Pancreat Dis Int; 2005 May;4(2):227-33
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  • METHODS: Subjects included 65 patients with primary HCC, 22 patients with hepatitis B and liver cirrhosis, 12 patients with metastatic liver cancer, 11 patients with hepatic hemangioma, and 20 healthy volunteers.

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  • (PMID = 15908320.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / MAGEA1 protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / alpha-Fetoproteins
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54. Diamantopoulou A, Kotziamani N, Tsitouridis I: Imaging findings of cavernous sinus hemangiomas. A report of two cases. Neuroradiol J; 2009 Aug 29;22(4):419-25
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  • [Title] Imaging findings of cavernous sinus hemangiomas. A report of two cases.
  • Extra-axial cavernous sinus hemangiomas are rare and account for less than 1% of parasellar tumors.
  • These lesions have characteristic radiological features but the differential diagnosis from parasellar meningiomas and schwannomas can be difficult.
  • Preoperative diagnosis is important due to the risk of severe intraoperative bleeding and the complex neurovascular structures of the cavernous sinus.
  • We describe two cases of cavernous sinus hemangiomas and review the imaging findings of these lesions.

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  • (PMID = 24207148.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Lauder C, Garcea G, Kanhere H, Maddern GJ: Sclerosing haemangiomas of the liver: two cases of mistaken identity. HPB Surg; 2009;2009:473591
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  • [Title] Sclerosing haemangiomas of the liver: two cases of mistaken identity.
  • We describe two cases where patients undergoing hepatic resection for metastatic disease of colorectal origin were found to have concomitant sclerosing haemangiomas.

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  • [Cites] Surg Clin North Am. 1989 Apr;69(2):297-314 [2538935.001]
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  • (PMID = 20066166.001).
  • [ISSN] 1607-8462
  • [Journal-full-title] HPB surgery : a world journal of hepatic, pancreatic and biliary surgery
  • [ISO-abbreviation] HPB Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2804040
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56. Bakari A, Afolabi OA, Adoga AA, Kodiya AM, Ahmad BM: Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria. BMC Res Notes; 2010;3:186
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  • BACKGROUND: The presence of a mass in the nose and paranasal sinuses may seem to be a simple problem; however it raises many questions about the differential diagnosis.
  • About 59 (77.6%) were benign, 2 (2.6%) were malignant and 15 (19.7%) were lost to follow up.
  • The commonest histological diagnosis is simple inflammatory nasal polyp in 28 (36.8%) patients and the least was nasal capillary hemangioma 2 (2.6%).
  • CONCLUSIONS: Nasal obstruction and rhinorrhea are the commonest symptoms of presentation, simple inflammatory nasal polyp is still the commonest histological pattern seen in our environment, and surgery is still the best modality of treatment for benign tumor thus the need for advocacy for early recognition and referral to the ENT surgeon.

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  • [Cites] Can Fam Physician. 1988 Dec;34:2706-9 [20469495.001]
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  • (PMID = 20618972.001).
  • [ISSN] 1756-0500
  • [Journal-full-title] BMC research notes
  • [ISO-abbreviation] BMC Res Notes
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2916008
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57. Lomenick JP, Backeljauw PF, Lucky AW: Growth, bone mineral accretion, and adrenal function in glucocorticoid-treated infants with hemangiomas-- a retrospective study. Pediatr Dermatol; 2006 Mar-Apr;23(2):169-74
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  • [Title] Growth, bone mineral accretion, and adrenal function in glucocorticoid-treated infants with hemangiomas-- a retrospective study.
  • Hemangiomas, common proliferative vascular tumors, can grow rapidly in the first months of life.
  • Using retrospective data, we examined growth velocity, changes in bone mineral density, and adrenal function in infants with hemangiomas treated with systemic glucocorticoids.
  • In conclusion, systemic glucocorticoid treatment in infants with hemangiomas slowed linear growth, but "catch-up" growth was observed after treatment ceased.
  • [MeSH-major] Adrenal Glands / drug effects. Calcification, Physiologic / drug effects. Glucocorticoids / therapeutic use. Hemangioma / drug therapy

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  • (PMID = 16650230.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucocorticoids
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58. Hazen PG, Carney JF, Engstrom CW, Turgeon KL, Reep MD, Tanphaichitr A: Proliferating hemangioma of infancy: successful treatment with topical 5% imiquimod cream. Pediatr Dermatol; 2005 May-Jun;22(3):254-6
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  • [Title] Proliferating hemangioma of infancy: successful treatment with topical 5% imiquimod cream.
  • A 4-month-old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall.
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Hemangioma / drug therapy. Skin Neoplasms / drug therapy

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  • (PMID = 15916578.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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59. Popescu I, Ciurea S, Romanescu D, Boros M: Isolated resection of the caudate lobe: indications, technique and results. Hepatogastroenterology; 2008 May-Jun;55(84):831-5
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  • BACKGROUND/AIMS: This paper reports a series of 24 isolated caudate lobe resections (ICLR), performed for 13 benign tumors (10 hemangiomas, 2 focal nodular hyperplasias, 1 adenoma) and 11 malignant tumors (3 hepatocarcinomas, 1 peripheral cholangiocarcinoma and 7 metastatic - 5 colorectal carcinomas, 1 breast carcinoma, 1 adrenal carcinoma).
  • METHODOLOGY: There were 10 hemangioma enucleations, 7 Spiegel lobe resections and 7 high dorsal resections.
  • Three patients died from generalized disease.
  • Another patient, with generalized disease, was lost from follow-up.
  • Malignant tumors located in the caudate lobe have a poor prognosis; local and, especially, distant metastases are frequent.
  • [MeSH-minor] Adenoma, Liver Cell / mortality. Adenoma, Liver Cell / pathology. Adenoma, Liver Cell / surgery. Adrenal Gland Neoplasms / mortality. Adrenal Gland Neoplasms / pathology. Adrenal Gland Neoplasms / surgery. Adult. Bile Duct Neoplasms / mortality. Bile Duct Neoplasms / pathology. Bile Duct Neoplasms / surgery. Breast Neoplasms / mortality. Breast Neoplasms / pathology. Breast Neoplasms / surgery. Carcinoma, Hepatocellular / mortality. Carcinoma, Hepatocellular / pathology. Carcinoma, Hepatocellular / surgery. Cholangiocarcinoma / mortality. Cholangiocarcinoma / pathology. Cholangiocarcinoma / surgery. Colorectal Neoplasms / mortality. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Female. Focal Nodular Hyperplasia / mortality. Focal Nodular Hyperplasia / pathology. Focal Nodular Hyperplasia / surgery. Hemangioma / mortality. Hemangioma / pathology. Hemangioma / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Postoperative Complications / etiology. Postoperative Complications / mortality. Postoperative Complications / surgery. Reoperation. Retrospective Studies. Survival Rate

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  • (PMID = 18705277.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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61. Ellenbogen JR, Joshi SM, Kitchen N: Development of cavernous haemangioma following radical chemo-radiotherapy for nasopharyngeal carcinoma. J Laryngol Otol; 2009 Aug;123(8):925-7
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  • [Title] Development of cavernous haemangioma following radical chemo-radiotherapy for nasopharyngeal carcinoma.
  • OBJECTIVE: We report an adult case of nasopharyngeal carcinoma treated with radical chemo-radiotherapy, with subsequent development of a histologically proved temporal cavernous haemangioma within the radiation field.
  • [MeSH-major] Hemangioma, Cavernous / etiology. Nasopharyngeal Neoplasms. Neoplasms, Radiation-Induced / etiology

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  • (PMID = 18796183.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 14
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62. Nicolae L, Iacob G, Poparda M, Popescu BO: Case report. Gelastic seizures in a patient with right gyrus cinguli astrocytoma. J Med Life; 2010 Oct-Dec;3(4):433-6
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  • OBJECTIVE AND IMPORTANCE: Gelastic seizure (GS) also known as "gelastic epilepsy" is a rare type of seizure associated with several different conditions such as tumors--hypothalamic hamartromas, tuberous sclerosis, hemangiomas, post infectious foci, cortical temporal dysplasia.
  • CLINICAL PRESENTATION: A 27 year-old male, right handed, was admitted for a 2 years history of very frequent gelastic seizures accompanied sometimes by simple motor partial seizures in both arms, more often being involved his left arm, without impairment of his consciousness state.
  • Diagnosis was made on native CT scan: minimal hypodense frontal right paramedian lesion, cerebral MRI showed a small well delimited right, parenchymal, homogeneous lesion (16/22/15 mm), involving gyrus cinguli, without perilesional edema and mass effect, hyperintense both on T1 and T2 MR sequences, non-enhancing after Gadolinium.

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  • (PMID = 21254744.001).
  • [ISSN] 1844-122X
  • [Journal-full-title] Journal of medicine and life
  • [ISO-abbreviation] J Med Life
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Other-IDs] NLM/ PMC3019062
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63. Liu FH, Hsueh C, Chao TC, Lin JD: Neck nodule and thyroid cancer in young without radiation exposure history. Pediatr Surg Int; 2009 Sep;25(9):785-8
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  • RESULTS: Of the 234 cases, 187 (79.9%) were surgically confirmed to be benign lesions, including four cases that were diagnosed as atypical adenoma.
  • Surgery confirmed 22 cases to be lesions that were non-thyroid in origin, including those developing from a cyst, soft tissue, and with a lymphatic origin.
  • Except in cases of follicular thyroid neoplasm, neck ultrasonography with FNAC could effectively identify the thyroid or non-thyroid origin of these masses with high-diagnostic accuracy.
  • [MeSH-minor] Adenoma / pathology. Adolescent. Biopsy, Fine-Needle. Carcinoma / pathology. Child. Child, Preschool. Cysts / pathology. Female. Hemangioma, Capillary / pathology. Humans. Infant. Lymphoma / pathology. Male. Neck / diagnostic imaging. Neurofibroma / pathology. Predictive Value of Tests. Retrospective Studies. Sensitivity and Specificity. Thyroiditis / pathology. Ultrasonography. Young Adult

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  • (PMID = 19629501.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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64. Islam S, Roustan Delatour NL, Salahdeen SR, Mai KT, Senterman M, Mokhtar GA: Cytologic features of benign solitary pulmonary nodules with radiologic correlation and diagnostic pitfalls: a report of six cases. Acta Cytol; 2009 Mar-Apr;53(2):201-10
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  • [Title] Cytologic features of benign solitary pulmonary nodules with radiologic correlation and diagnostic pitfalls: a report of six cases.
  • BACKGROUND: The solitary pulmonary nodule (SPN) is a common radiologic abnormality often detected incidentally.
  • The majority of SPNs represent benign processes, including granulotmatous inflammation, bronchogenic cysts and hamartomata.
  • CASES: We report the cytologic features of 6 cases of benign SPN: exogenous lipid pneumonia, sclerosing hemangioma, hemartoma, bronchogenic cyst, fungal granuloma and solitary fibrous tumor.
  • CONCLUSION: Cytologically, lack of nuclear atypia with bland chromatin is useful in separating benign from malignant SPN.
  • Radiologically, smaller lesions with smooth, well-defined margins and calcifications are more likely to be benign.
  • Our cases illustrate the cytologic and immunohistochemical features that can help to make a more precise diagnosis.
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Bronchogenic Cyst / pathology. Bronchogenic Cyst / radiography. Female. Granuloma / microbiology. Granuloma / pathology. Granuloma / radiography. Hamartoma / pathology. Hamartoma / radiography. Humans. Immunohistochemistry. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Lung Neoplasms / radiography. Male. Middle Aged. Mycoses / pathology. Mycoses / radiography. Pneumonia, Lipid / pathology. Pneumonia, Lipid / radiography. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 19365977.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Antonopoulos C, Karagianni M, Zolindaki C, Anagnostou E, Vagianos C: Cavernous hemangioma of infrahyoid carotid sheath and review of the literature on carotid sheath tumors. Head Neck; 2009 Oct;31(10):1381-6
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  • [Title] Cavernous hemangioma of infrahyoid carotid sheath and review of the literature on carotid sheath tumors.
  • Hemangiomas are benign congenital neoplasms, which, when located in the head and neck region, may be easily misdiagnosed due to their infrequent localization.
  • METHODS AND RESULTS: We report an unusual case of cavernous hemangioma of the infrahyoid carotid sheath presenting as palpable mass in a 51-year-old woman with no prior medical history.
  • CONCLUSIONS: CT, MRI, and MR angiography would help to locate hemangiomas of carotid sheath, but only surgical excision and histopathology can reveal their true nature.
  • [MeSH-major] Carotid Body Tumor / surgery. Hemangioma, Cavernous / surgery

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  • [Copyright] (c) 2009 Wiley Periodicals, Inc.
  • (PMID = 19260115.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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66. Pamir MN, Kilic T, Ozek MM, Ozduman K, Türe U: Non-meningeal tumours of the cavernous sinus: a surgical analysis. J Clin Neurosci; 2006 Jul;13(6):626-35
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  • [Title] Non-meningeal tumours of the cavernous sinus: a surgical analysis.
  • The purpose of this study was first to analyse, define and summarise the individual characteristics of different non-meningeal tumours of the cavernous sinus and, secondly, to stress that their surgery can be accomplished with acceptable morbidity and rewarding results when those characteristics are considered.
  • A retrospective analysis of 42 cases of benign non-meningeal tumours of the cavernous sinus operated on at Marmara University between April 1992 and April 2003 is presented.
  • The study cohort consisted of 13 pituitary adenomas, 11 trigeminal schwannomas, seven chordomas, three chondrosarcomas, two juvenile angiofibromas, two epidermoid tumours, one plasmacytoma, one cavernous haemangioma and one internal carotid plexus schwannoma.
  • Non-meningeal tumours of the cavernous sinus can be surgically resected with acceptable morbidity and mortality.
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant / methods. Cranial Nerve Neoplasms. Female. Follow-Up Studies. Hemangioma, Cavernous, Central Nervous System. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neurilemmoma / surgery. Pituitary Neoplasms / surgery. Retrospective Studies. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 16860718.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Scotland
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67. Li L, Xu ZG, Sun YJ, Ma L: [Clinical characteristics and treatment options of cutaneous vessel abnormalities]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2009 Feb;31(1):37-41
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  • Patients were classified according to International Society for the Study of Vascular Anomalies (ISSVA) classification method.
  • RESULTS: Of the 384 patients, infantile hemangioma was confirmed in 185 patients (male : female = 1 : 1.7).
  • Congenital hemangioma was confirmed in 132 patients (male : female = 1 : 1.9).
  • CONCLUSIONS: Infantile hemangioma and congenital hemangioma are two common cutaneous vessel abnormalities in children.
  • Cutaneous vessel abnormality with endothelial cell proliferation has an earlier onset age.
  • [MeSH-major] Hemangioma / therapy. Skin Neoplasms / therapy

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  • (PMID = 19317056.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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68. Cartwright G, Bailey BM, Lane RJ, Messiha A: A diagnostic dilemma of intracranial pathology: coincidence or the result of cranial trauma? BMJ Case Rep; 2010;2010
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A subsequent MRI scan showed the lesion to be a cavernous haemangioma.
  • [MeSH-major] Brain Neoplasms / complications. Brain Neoplasms / diagnosis. Epilepsy, Tonic-Clonic / complications. Epilepsy, Tonic-Clonic / diagnosis. Facial Injuries / complications. Facial Injuries / diagnosis. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / diagnosis. Intracranial Hemorrhage, Traumatic / complications. Intracranial Hemorrhage, Traumatic / diagnosis. Intracranial Hemorrhages / complications. Intracranial Hemorrhages / diagnosis. Muscle Weakness / complications. Muscle Weakness / diagnosis
  • [MeSH-minor] Brain / pathology. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Motor Cortex / pathology. Neurologic Examination. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 22797209.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027484
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69. Czernik A, Bystryn JC: Does imiquimod work in infantile hemangiomas? J Am Acad Dermatol; 2007 Sep;57(3):535; author reply 536
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does imiquimod work in infantile hemangiomas?
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Hemangioma / drug therapy

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  • [CommentOn] J Am Acad Dermatol. 2007 Jan;56(1):63-8 [17190622.001]
  • (PMID = 17707162.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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70. Corrêa PH, Nunes LC, Johann AC, Aguiar MC, Gomez RS, Mesquita RA: Prevalence of oral hemangioma, vascular malformation and varix in a Brazilian population. Braz Oral Res; 2007 Jan-Mar;21(1):40-5
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  • [Title] Prevalence of oral hemangioma, vascular malformation and varix in a Brazilian population.
  • Hemangioma, vascular malformation and varix are benign vascular lesions, common in the head and neck regions.
  • The aim of this study was to estimate the prevalence of and to obtain clinical data on oral hemangioma, vascular malformation and varix in a Brazilian population.
  • Clinical data on those lesions were retrieved from the clinical forms from the files of the Oral Diagnosis Service, School of Dentistry, Federal University of Minas Gerais, Brazil, from 1992 to 2002.
  • A total of 2,419 clinical forms in the 10-year period were evaluated, of which 154 (6.4%) cases were categorized as oral hemangioma, oral vascular malformation or oral varix.
  • Females had more oral hemangioma and oral varix than males.
  • Oral hemangioma and oral varix were more prevalent in the ventral surface of the tongue and oral vascular malformation, in the lips.
  • Oral hemangioma was treated with sclerotherapy (54.5%), and vascular malformation was managed with sclerotherapy and surgery (19.4% each).
  • The data of this study suggests that benign vascular lesions are unusual alterations on the oral mucosa and jaws.
  • [MeSH-major] Arteriovenous Malformations / epidemiology. Hemangioma / epidemiology. Mouth Neoplasms / epidemiology. Varicose Veins / epidemiology


71. Becker H: [Intracerebral hemorrhage misjudged as tumor]. Clin Neuroradiol; 2010 Aug;20(3):161-4
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  • Report of a 33-year-old woman who had sudden vision problems and homonymous hemianopia on the left.
  • Histologically, a bleeding of a cavernous hemangioma was found.
  • The patient appealed to the fact-finding board for medical liability questions because she had not been admitted to a hospital immediately after the CCT.
  • [MeSH-major] Brain Neoplasms / radiography. Cerebral Hemorrhage / radiography. Diagnostic Errors / prevention & control. Hemangioma, Cavernous, Central Nervous System / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 20625692.001).
  • [ISSN] 1869-1447
  • [Journal-full-title] Clinical neuroradiology
  • [ISO-abbreviation] Clin Neuroradiol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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72. Tronina SA, Bobrova NF, Khrinenko VP: Combined surgical method of orbital and periorbital hemangioma treatment in infants. Orbit; 2008;27(4):249-57
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined surgical method of orbital and periorbital hemangioma treatment in infants.
  • PURPOSE: To analyze the results of application of combined surgical treatment in different forms of hemangioma in infants.
  • MATERIALS AND METHODS: One hundred seventy-four children with different forms of orbital and periorbital hemangiomas aged 1-16 months (mean age 5.2 + 1.97 months) were operated on at the pediatric ophthalmology department.
  • Fast growth of hemangioma, both superficial (intradermal) and deep (subdermal and orbital) localization, significant deformity of eyelids, with narrowing of eye fissure were the indications for surgical treatment.
  • The combined-staged method, including cryosurgery of superficial intradermal lesions and surgical excision of subdermal and/or orbital parts of the tumor in different combinations depending on the form and depth of hemangioma spreading, was applied.
  • CONCLUSION: Combined surgical method of treatment of progressive capillary hemangiomas by using cryosurgery and surgical excision in infants allows the choice of optimum tactics depending on features of the course and clinical picture in each individual case and provides achievement of high cosmetic and functional result of treatment.
  • [MeSH-major] Eyelid Neoplasms / surgery. Hemangioma, Capillary / surgery. Orbital Neoplasms / surgery. Skin Neoplasms / surgery

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  • (PMID = 18716962.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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73. Grzegorczyk V, Brasseur-Daudruy M, Labadie G, Cellier C, Verspyck E: Prenatal diagnosis of a nasal glioma. Pediatr Radiol; 2010 Oct;40(10):1706-9
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  • [Title] Prenatal diagnosis of a nasal glioma.
  • The child underwent surgery at 5 months and final diagnosis was made on pathological examination.
  • Therefore, a vascular lesion and a clinical aspect mimicking a haemangioma should not be considered sufficient to reach the final diagnosis.
  • [MeSH-major] Glioma / diagnostic imaging. Nose / pathology. Nose Neoplasms / diagnostic imaging. Prenatal Diagnosis
  • [MeSH-minor] Adult. Female. Fetal Diseases / diagnostic imaging. Fetal Diseases / pathology. Humans. Pregnancy. Treatment Outcome. Ultrasonography

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  • (PMID = 20401478.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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74. De Bona M, Bellumat A, De Boni M: Capsule endoscopy for the diagnosis and follow-up of blue rubber bleb nevus syndrome. Dig Liver Dis; 2005 Jun;37(6):451-3
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  • [Title] Capsule endoscopy for the diagnosis and follow-up of blue rubber bleb nevus syndrome.
  • Blue rubber bleb nevus syndrome is a rare disorder characterised by cutaneous and gastrointestinal vascular malformations.
  • Hemangiomas on his back and the multiple bluish vascular lesions in the distal ileum revealed by capsule endoscopy led to the diagnosis of blue rubber bleb nevus syndrome.
  • [MeSH-major] Endoscopes, Gastrointestinal. Ileal Neoplasms / diagnosis. Nevus, Blue / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 15893285.001).
  • [ISSN] 1590-8658
  • [Journal-full-title] Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • [ISO-abbreviation] Dig Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Gastrointestinal Agents; RWM8CCW8GP / Octreotide
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75. Ozer E, Yücesoy K, Kalemci O: Demonstrated rapid growth of a corpus callosum cavernous angioma within a short period of time. J Neurosurg Sci; 2005 Dec;49(4):155-8; discussion 158
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  • [Title] Demonstrated rapid growth of a corpus callosum cavernous angioma within a short period of time.
  • Cavernous angiomas are uncommon central nervous system vascular malformations.
  • In this study we report a case of corpus callosum cavernous angioma which demonstrated rapid growth within a short period of time.
  • Corpus callosum cavernous angiomas have distinct features regarding growth and should be treated more carefully by giving more importance to surgical removal rather than a conservative approach.
  • [MeSH-major] Brain Neoplasms / pathology. Corpus Callosum / pathology. Hemangioma, Cavernous, Central Nervous System / pathology

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  • (PMID = 16374407.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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76. Farinelli A, Ferrara E, Cirillo M, Zorzi F: [Right ventricular cavernous hemangioma: a rare cardiac primary neoplasia]. Ital Heart J Suppl; 2005 Aug;6(8):498-501
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  • [Title] [Right ventricular cavernous hemangioma: a rare cardiac primary neoplasia].
  • [Transliterated title] Grosso emangioma cavernoso del ventricolo destro: una neoplasia primitiva cardiaca molto rara.
  • Among benign cardiac tumors, cavernous hemangioma has a prevalence of 2.8%.
  • Less invasive diagnostic techniques such as transthoracic echocardiography allow for the diagnosis to be made during life with definitive surgical treatment.
  • We report a representative case of right ventricular cavernous hemangioma, which mimicked right ventricular failure associated with systolic pulmonary flow tract obstruction.
  • [MeSH-major] Heart Neoplasms. Hemangioma, Cavernous
  • [MeSH-minor] Aged. Diagnosis, Differential. Echocardiography. Female. Follow-Up Studies. Heart Ventricles. Humans. Radiography, Thoracic. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Ventricular Dysfunction, Right / diagnosis

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  • (PMID = 16161504.001).
  • [ISSN] 1129-4728
  • [Journal-full-title] Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology
  • [ISO-abbreviation] Ital Heart J Suppl
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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77. Seo HI, Jo HJ, Sim MS, Kim S: Right trisegmentectomy with thoracoabdominal approach after transarterial embolization for giant hepatic hemangioma. World J Gastroenterol; 2009 Jul 21;15(27):3437-9
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  • [Title] Right trisegmentectomy with thoracoabdominal approach after transarterial embolization for giant hepatic hemangioma.
  • Hepatic hemangiomas need to be treated surgically in cases where they are accompanied with symptoms, have a risk of rupture, or are hardly distinguishable from malignancy.
  • The present authors conducted embolization of the right hepatic artery one day before an operation for a huge hemangioma accompanied with symptoms and confirmed a decrease in its size.
  • The authors performed a right trisegmentectomy through a J-shape incision, using a thoracoabdominal approach, and safely removed a giant hemangioma of 32.0 cm x 26.5 cm x 8.0 cm in size and 2300 g in weight.
  • Even for inexperienced surgeons, a J-shape incision with a thoracoabdominal approach is considered a safe and useful method when right-side hepatectomy is required for a large mass in the right liver.
  • [MeSH-major] Embolization, Therapeutic / methods. Hemangioma, Cavernous / surgery. Hepatectomy / methods. Liver. Liver Neoplasms / surgery

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  • [Cites] Abdom Imaging. 2001 Sep-Oct;26(5):510-4 [11503090.001]
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  • (PMID = 19610149.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2712909
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78. Svajdler M, Bohus P, Baumöhlová H, Sokol L, Bielek J: [Epithelioid hemangioma of the foot]. Cesk Patol; 2006 Apr;42(2):86-90
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  • [Title] [Epithelioid hemangioma of the foot].
  • Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia, EH/ALHE) is a rare benign angioproliferative lesion which typically occurs in the region of the head and neck.
  • Immunohistochemistry may be helpful in settling the diagnosis.
  • [MeSH-major] Angiolymphoid Hyperplasia with Eosinophilia / pathology. Foot Diseases / pathology. Hemangioendothelioma, Epithelioid / pathology

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  • (PMID = 16715634.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] slo
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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79. Wu JL, Wu CC, Wang SJ, Chen YJ, Huang GS, Wu SS: Imaging strategies in intramuscular haemangiomas: an analysis of 20 cases. Int Orthop; 2007 Aug;31(4):569-75
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  • [Title] Imaging strategies in intramuscular haemangiomas: an analysis of 20 cases.
  • The purpose of this study was to review the correlation between the imaging studies and the histological findings in the diagnosis of this disease.
  • We retrospectively reviewed 21 lesions in 20 patients (median age, 23.7 years old) who had been diagnosed with cavernous haemangiomas (n=11), capillary (n=6), and mixed (n=3) types.
  • Based on the imaging studies, the rate of accurate prediction of intramuscular haemangioma using MRI in our study was 90%.
  • Using the preoperative imaging studies and surgical excisions, only one (5%) local recurrence happened 2 years after marginal excision.
  • The remaining patients were free of disease.
  • [MeSH-major] Hemangioma / pathology. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Angiography / methods. Child. Female. Humans. Male. Neoplasm Recurrence, Local / prevention & control. Positron-Emission Tomography. Retrospective Studies

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  • [Cites] Surgery. 1985 Jan;97(1):36-41 [3966228.001]
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  • (PMID = 17021834.001).
  • [ISSN] 0341-2695
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2267631
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80. Van Gompel JJ, Griessenauer CJ, Scheithauer BW, Amrami KK, Spinner RJ: Vascular malformations, rare causes of sciatic neuropathy: a case series. Neurosurgery; 2010 Oct;67(4):1133-42; discussion 1142
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  • Intraoperative histological study confirmed the presence of a venous angioma, an arteriovenous malformation, a venous malformation associated with Klippel-Trenaunay syndrome, and a capillary hemangioma.
  • In these cases, exploration and fascicular biopsy provided a diagnosis; external and limited internal neurolysis improved pain.

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  • (PMID = 20881578.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Askri A, Mannai S, Landolsi S, Ben Farhat L, Said W, Dali N, Khalfallah MT, Hendaoui L: [Hepatic epithelioid hemangioendothelioma: review of 3 cases]. J Radiol; 2009 Mar;90(3 Pt 1):310-4
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  • [Transliterated title] Hémangioendothéliome épithélioïde hépatique: à propos de 3 cas.
  • EHE is an intermediate-grade malignancy, between benign hemangioma and angiosarcoma, with variable aggressiveness.
  • Involvement often is multinodular simulating metastases from a primatry extra-hepatic malignancy leading to delays in diagnosis.
  • [MeSH-major] Hemangioendothelioma, Epithelioid / diagnosis. Liver Neoplasms / diagnosis

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  • (PMID = 19421116.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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82. Kayias EH, Drosos GI, Kazakos KI, Iatrou C, Blatsoukas KS, Verettas DA: Intramuscular haemangioma of the extensor pollicis brevis muscle with periosteal reaction of the radius: a case report and review of the literature. J Int Med Res; 2007 Sep-Oct;35(5):724-30
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  • [Title] Intramuscular haemangioma of the extensor pollicis brevis muscle with periosteal reaction of the radius: a case report and review of the literature.
  • We report the rare case of a histologically proven mixed-type intramuscular haemangioma, adjacent to the periosteum of the radius, that caused a periosteal reaction.
  • Diagnosis was established on the basis of plain radiographs and magnetic resonance imaging, and was confirmed by histology.
  • From a review of the literature, it is evident that the terminology for haemangiomas causing regional bone changes is unclear.
  • A new classification of the intramuscular haemangiomas is proposed in order to distinguish between lesions that, according to current knowledge, exhibit radiological and clinical areas of overlap.
  • [MeSH-major] Hemangioma / diagnosis. Muscle Neoplasms / diagnosis

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  • (PMID = 17900409.001).
  • [ISSN] 0300-0605
  • [Journal-full-title] The Journal of international medical research
  • [ISO-abbreviation] J. Int. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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83. de Koning DB, Drenth JP, Oyen WJ, Wagenaar M, Aliredjo RP, Nagengast FM: Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case. Dis Colon Rectum; 2007 Nov;50(11):1987-91
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  • [Title] Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case.
  • This lesion was found to be a sclerosing hemangioma.
  • We found an aberrant beta-catenin expression on immunohistochemical staining, suggesting that sclerosing hemangioma and familial adenomatous polyposis share the same pathophysiology.
  • It is important to be aware of the association of familial adenomatous polyposis and sclerosing hemangioma.
  • [MeSH-major] Adenomatous Polyposis Coli / epidemiology. Positron-Emission Tomography. Pulmonary Sclerosing Hemangioma / epidemiology

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  • [Cites] J Surg Oncol. 2004 Sep 15;87(4):187-90 [15334634.001]
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  • (PMID = 17473941.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / beta Catenin; 40871-47-4 / 2-fluoro-2-deoxyglucose-6-phosphate; 56-73-5 / Glucose-6-Phosphate
  • [Other-IDs] NLM/ PMC3234159
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84. Leng T, Wang X, Huo R, Cheng Z, Feng Y: The value of three-dimensional computed tomographic angiography in the diagnosis and treatment of vascular lesions. Plast Reconstr Surg; 2008 Nov;122(5):1417-24
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  • [Title] The value of three-dimensional computed tomographic angiography in the diagnosis and treatment of vascular lesions.
  • BACKGROUND: The accurate classification of vascular lesions is important because treatment and prognosis vary from type to type.
  • The authors' study was designed to evaluate the value of three-dimensional computed tomographic angiography in the diagnosis and treatment of vascular lesions.
  • RESULTS: Three-dimensional computed tomographic angiography accurate distinguished hemangiomas and vascular malformations, which was proven pathologically.
  • CONCLUSIONS: The authors' study suggests that three-dimensional computed tomographic angiography is helpful in differential diagnosis of hemangiomas and vascular malformations and provides a global overview of the lesions.
  • [MeSH-major] Angiography / methods. Facial Neoplasms / radiography. Hemangioma / radiography. Imaging, Three-Dimensional / methods. Intracranial Arteriovenous Malformations / radiography. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Male. Middle Aged

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  • [ErratumIn] Plast Reconstr Surg.2009 Feb;123(2):771
  • (PMID = 18971725.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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85. Wachtlin J, Spyridaki M, Stroux A, Bechrakis NE, Foerster M: [Therapy for peripapillary located and large choroidal haemangioma with PDT 'paint-brush technique']. Klin Monbl Augenheilkd; 2009 Nov;226(11):933-8
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  • [Title] [Therapy for peripapillary located and large choroidal haemangioma with PDT 'paint-brush technique'].
  • BACKGROUND: Today photodynamic therapy (PDT) with Verteporfin is the standard treatment option for symptomatic choroidal haemangiomas.
  • Nevertheless, peripapillary or large haemangiomas pose a therapeutic dilemma, since severe adverse events have been demonstrated in cases where the optic disc was included in the treatment spot.
  • In addition due to the size and the shape of the laser spot, peripapillary and large haemangiomas can only be undertreated or overtreated (with overlapping multiple spots).
  • With the presented new "paint-brush technique" it is possible to treat peripapillary and large choroidal haemangiomas completely without danger for the optic disc and without overtreatment.
  • In total, 13 eyes of 13 patients (6 with peripapillary and 7 with large choroidal haemangiomas) have been treated.
  • CONCLUSION: The use of the PDT "paint-brush technique" allows complete treatment of choroidal haemangiomas under visual control.
  • The technique is a safe and effective amendment in the treatment of symptomatic choroidal haemangiomas.
  • [MeSH-major] Choroid Neoplasms / drug therapy. Hemangioma / drug therapy. Photochemotherapy / methods

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart-New York.
  • (PMID = 19798625.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Porphyrins; 129497-78-5 / verteporfin
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86. Hekimoglu K, Ustundag Y: Cavernous hemangioma with arterioportal and portosystemic shunts: precise diagnosis with dynamic multidetector computed tomography imaging. Abdom Imaging; 2010 Jun;35(3):328-31
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  • [Title] Cavernous hemangioma with arterioportal and portosystemic shunts: precise diagnosis with dynamic multidetector computed tomography imaging.
  • Cavernous hemangiomas with shunt formations have been a recently recognized entity.
  • Arterioportal (AP) shunts with cavernous hemangiomas have been described.
  • In this study, we report an atypical cavernous hemangioma associated with portal hypertension.
  • Cavernous hemangioma with AP and PS shunts formations was precisely demonstrated with dynamic multidetector CT imaging.
  • [MeSH-major] Hemangioma, Cavernous / radiography. Portal Vein / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 19437066.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Buckmiller LM, Francis CL, Glade RS: Intralesional steroid injection for proliferative parotid hemangiomas. Int J Pediatr Otorhinolaryngol; 2008 Jan;72(1):81-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intralesional steroid injection for proliferative parotid hemangiomas.
  • OBJECTIVE: To evaluate the efficacy of proliferative phase intralesional steroid injections in the treatment of parotid hemangiomas.
  • DESIGN: Retrospective analysis of pediatric patients with parotid hemangiomas treated with intralesional steroid injections during the proliferative phase.
  • METHODS: Between 2001 and 2006, 21 patients received steroid injections for 23 parotid hemangiomas (bilateral in 2 patients).
  • CONCLUSION: Parotid hemangiomas can be effectively controlled with proliferative phase intralesional steroid injections.
  • [MeSH-major] Betamethasone / administration & dosage. Glucocorticoids / administration & dosage. Hemangioma / drug therapy. Parotid Neoplasms / drug therapy. Triamcinolone / administration & dosage

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  • (PMID = 18054392.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Glucocorticoids; 1ZK20VI6TY / Triamcinolone; 9842X06Q6M / Betamethasone
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88. Lin H, Chen SH, Yin GQ, Li D, Liu QF: [Expression and significance of TRAIL protein and mRNA in hemangioma]. Zhonghua Zheng Xing Wai Ke Za Zhi; 2007 Mar;23(2):93-6
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  • [Title] [Expression and significance of TRAIL protein and mRNA in hemangioma].
  • OBJECTIVE: To detect the expression of TRAIL protein and mRNA in hemangiomas and vascular malformations.
  • METHODS: Sections of 33 proliferative hemangiomas,28 involuting hemangiomas and 29 vascular malformations were immunostained for TRAIL protein, TRAIL mRNA was examined by in situ hybridization in these tissue.
  • RESULTS: The TRAIL protein positive rates in proliferative hemangiomas, involuting hemangiomas, vascular malformations and normal skins were respectively 45.45% (15/33), 78.57% (22/28), 0% and 0%.
  • The difference between proliferative hemangiomas and involuting hemangiomas was also significant (P < 0.01).
  • The difference between proliferative hemangiomas and involuting hemangiomas was also significant (P < 0.01).
  • CONCLUSIONS: TRAIL could induce endothelial apoptosis and cause regression of hemangiomas.
  • [MeSH-major] Hemangioma / metabolism. TNF-Related Apoptosis-Inducing Ligand / metabolism

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  • (PMID = 17554866.001).
  • [ISSN] 1009-4598
  • [Journal-full-title] Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
  • [ISO-abbreviation] Zhonghua Zheng Xing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / TNF-Related Apoptosis-Inducing Ligand
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89. Yuan SM, Shinfeld A, Lavee J, Kuperstein R, Haizler R, Raanani E: Imaging morphology of cardiac tumours. Cardiol J; 2009;16(1):26-35
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  • [Title] Imaging morphology of cardiac tumours.
  • Thirty (88.2%) tumours were primary [19 (55.9%) myxomas, 8 (23.5%) papillary fibroelastomas, and 1 (2.9%) cavernous hemangioma were benign, 1 (2.9%) recurrent fibrous histiocytoma (undifferentiated sarcoma) and 1 (2.9%) leiomyosarcoma were malignant], and 4 (11.8%) were secondary [1 (2.9%) metastatic cardiac leiomyoma, and 3 (8.8%) were renal cell carcinomas].
  • The cavernous hemangioma was isointense on magnetic resonance imaging and tensile and slithy in gross specimen.
  • CONCLUSIONS: Imaging morphology plays a key role in the preoperative differential diagnosis of cardiac tumours.
  • Imaging features could reliably predict primary versus secondary, and benign versus malignant among cardiac tumours.
  • The accurate preoperative imaging assessment of cardiac tumours necessitating surgical resection has become increasingly important in the decision-making of a surgical approach, method, and resection extent.
  • [MeSH-major] Diagnostic Imaging. Heart Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Cardiac Surgical Procedures. Diagnosis, Differential. Echocardiography, Doppler, Color. Echocardiography, Transesophageal. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Predictive Value of Tests. Preoperative Care. Tomography, X-Ray Computed

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  • (PMID = 19130413.001).
  • [ISSN] 1897-5593
  • [Journal-full-title] Cardiology journal
  • [ISO-abbreviation] Cardiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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90. Guo S, Hunt MG, Superstein R: Treatment of infantile hemangiomas. J Pediatr Ophthalmol Strabismus; 2010 Jul-Aug;47(4):198-201
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of infantile hemangiomas.
  • [MeSH-major] Eyelid Neoplasms / therapy. Hemangioma / therapy

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  • (PMID = 20635807.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Interview
  • [Publication-country] United States
  • [Chemical-registry-number] 9Y8NXQ24VQ / Propranolol
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91. Ranalli NJ, Huang JH, Lee EB, Zhang PJ, Siegelman ES, Zager EL: Hemangiomas of the brachial plexus: a case series. Neurosurgery; 2009 Oct;65(4 Suppl):A181-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemangiomas of the brachial plexus: a case series.
  • OBJECTIVE: Hemangiomas of the brachial plexus are very rare, and there has not been a collection of multiple cases published in the literature to date.
  • Extraneural brachial plexus hemangiomas typically present with similar signs and symptoms as nerve sheath tumors, including pain, paresthesia, and occasionally weakness, in addition to nonspecific imaging findings, making their diagnosis difficult.
  • Exploratory surgery can lead to significant bleeding and nerve injury when a hemangioma or an associated aneurysm is encountered intraoperatively.
  • We present 5 cases of extraneural hemangiomas causing brachial plexopathy, including pre-, intra-, and postoperative decision making, with an emphasis on diagnostic and management issues as well as outcomes.
  • METHODS: A retrospective review was performed of 5 patients who underwent surgery at a university teaching hospital between 1995 and 2007 for exploration of brachial plexus lesions that were confirmed to be hemangiomas at pathological examination.
  • RESULTS: All 5 patients presented with findings on history, physical examination, imaging, and electromyography suggesting a diagnosis of nerve sheath tumor.
  • Pathological evaluation identified 3 venous hemangiomas, 1 hemangioma with arteriovenous malformation features, and 1 Masson hemangioma associated with a large aneurysm.
  • CONCLUSION: Extraneural hemangiomas of the brachial plexus are very rare, but a high index of suspicion and appropriate preoperative evaluation, including angiography with the option for embolization, can result in decreased intraoperative hemorrhage and better patient outcomes.
  • [MeSH-major] Brachial Plexus / physiopathology. Brachial Plexus Neuropathies / diagnosis. Brachial Plexus Neuropathies / physiopathology. Hemangioma / diagnosis. Hemangioma / physiopathology
  • [MeSH-minor] Adolescent. Adult. Aged. Angiography, Digital Subtraction. Biopsy. Diagnosis, Differential. Diagnostic Imaging. Electromyography. Embolization, Therapeutic. Female. Humans. Middle Aged. Nerve Sheath Neoplasms / diagnosis. Neurosurgical Procedures / methods. Preoperative Care / methods. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19927066.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Weidemann F, Strotmann JM, Breunig F, Niemann M, Maag R, Baron R, Eggert AO, Wanner C: Misleading terms in Anderson-Fabry disease. Eur J Clin Invest; 2008 Mar;38(3):191-6
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  • [Title] Misleading terms in Anderson-Fabry disease.
  • BACKGROUND: Signs and symptoms of classic Fabry disease manifest itself on the skin (angiokeratoma), the nervous system (acroparaesthesia), the heart (restrictive cardiomyopathy) and a variety of other organs.
  • MATERIALS AND METHODS: Diagnosis of Fabry disease was confirmed by genetic tests in a cohort of 100 patients and a standardized examination programme was performed in all patients.
  • RESULTS: Among the 47 male and 53 female patients (mean age 41 +/- 16 years) with genetically proven disease, the Fabry-type vascular skin lesions were without hyperkeratotic aspect and keratomas were virtually absent.
  • CONCLUSIONS: Our findings suggest that some terms used to describe signs and symptoms of Fabry disease are historically derived and do not comply with state-of-the-art examination.
  • We propose to replace the term 'angiokeratoma' with 'angioma', the term 'acroparaesthesia' with 'neuropathic pain' and the term 'restrictive cardiomyopathy' with 'cardiac hypertrophic storage disease'.
  • As most of the physicians are not familiar with Fabry disease, terms used in the past might prevent the correct diagnosis of a potentially treatable disease.
  • [MeSH-major] Angiokeratoma / diagnosis. Cardiovascular Diseases / diagnosis. Fabry Disease / diagnosis. Paresthesia / diagnosis
  • [MeSH-minor] Adult. Cohort Studies. Diagnosis, Differential. Echocardiography, Doppler. Female. Humans. Male. Middle Aged. Skin Diseases / pathology. Terminology as Topic


93. Petroianu A, Teixeira BC, de Alencar LF: Partial splenectomy for treatment of splenic hemangioma. Chirurgia (Bucur); 2009 Jul-Aug;104(4):483-6
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  • [Title] Partial splenectomy for treatment of splenic hemangioma.
  • BACKGROUND: Although splenectomy is helpful in the management of splenic hemangioma, this procedure may result in a greater morbidity and even mortality, mainly caused by sepsis, when this operation is performed in children and teenagers, due to their immune deficiency.
  • In order to avoid the adverse effects associated with the asplenism, this paper proposes partial splenectomy is proposed to treat splenic hemangioma.
  • METHOD/CASE REPORT: A 13-year-old boy with hemangioma of the lower pole of the spleen was cared for by the authors.
  • CONCLUSION: Partial splenectomy should be considered and recommended as a good surgical treatment for splenic hemangioma.
  • [MeSH-major] Hemangioma / surgery. Splenectomy / methods. Splenic Neoplasms / surgery

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  • (PMID = 19886058.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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94. Bernatik T, Seitz K, Blank W, Schuler A, Dietrich CF, Strobel D: Unclear focal liver lesions in contrast-enhanced ultrasonography--lessons to be learned from the DEGUM multicenter study for the characterization of liver tumors. Ultraschall Med; 2010 Dec;31(6):577-81
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  • MATERIALS AND METHODS: CEUS was performed on 1349 liver lesions with an unclear diagnosis after native ultrasound using a standardized protocol (phase inversion; low MI < 0.4; Sonovue Bolus 1.2 - 4.8 ml).
  • The diagnosis based on CEUS results was compared to the final diagnosis (histology: n = 1006; MRI: n = 269; CT: n = 269 - multiple examinations possible).
  • RESULTS: Of the 1349 enclosed liver lesions, 20 could not be definitively diagnosed even using all diagnostic steps including histology (the others were proven to be benign n = 573 or malignant n = 756).
  • Most of them were benign (n = 67) on final diagnosis.
  • The CEUS diagnosis was wrong for 39 lesions.
  • However, only 8 lesions classified as benign by CEUS turned out to be malignant.
  • Two lesions diagnosed by CEUS as hemangiomas turned out to be an HCC and a metastasis.
  • One lesion classified as benign by CEUS was ultimately diagnosed as a lymphoma.
  • The CEUS diagnosis of benign was only incorrect in a few cases.
  • [MeSH-minor] Biopsy. Biopsy, Fine-Needle. Contrast Media / administration & dosage. Diagnosis, Differential. Focal Nodular Hyperplasia / pathology. Focal Nodular Hyperplasia / ultrasonography. Hemangioma / pathology. Hemangioma / ultrasonography. Humans. Liver / pathology. Liver / ultrasonography. Liver Diseases / pathology. Liver Diseases / ultrasonography. Phospholipids. Regional Blood Flow / physiology. Sensitivity and Specificity. Sulfur Hexafluoride

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20740399.001).
  • [ISSN] 1438-8782
  • [Journal-full-title] Ultraschall in der Medizin (Stuttgart, Germany : 1980)
  • [ISO-abbreviation] Ultraschall Med
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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95. Lago-Méndez L, Blanco-Carrión A, Diniz-Freitas M, Gándara-Vila P, García-García A, Gándara-Rey JM: Rhomboid glossitis in atypical location: case report and differential diagnosis. Med Oral Patol Oral Cir Bucal; 2005 Mar-Apr;10(2):123-7
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  • [Title] Rhomboid glossitis in atypical location: case report and differential diagnosis.
  • Median rhomboid glossitis (MRG) is an uncommon benign abnormality of the tongue, most frequently affecting men.
  • This paper reports a case of rhomboid glossitis in a 61-year-old man who consulted for a painless raised lesion on the dorsum of the tongue, in left paramedial (not medial) location.
  • Other diagnoses considered but ruled out on the basis of the clinical and histopathological findings were haemangioma, pyogenic granuloma, amyloidosis, granular cell tumour, and squamous cell carcinoma.
  • [MeSH-minor] Amyloidosis / diagnosis. Antifungal Agents / therapeutic use. Candida albicans / isolation & purification. Candidiasis, Oral / diagnosis. Diagnosis, Differential. Granular Cell Tumor / diagnosis. Granuloma, Pyogenic / diagnosis. Hemangioma / diagnosis. Humans. Male. Middle Aged. Tongue Neoplasms / diagnosis

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  • (PMID = 15735544.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antifungal Agents
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96. Riberi A, Gariboldi V, Grisoli D, Collart F: [Cardiac tumors]. Rev Pneumol Clin; 2010 Feb;66(1):95-103
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  • Primary cardiac tumor is a rare disease, with an incidence ranging from 0.001 to 0.03%.
  • Eighty percent of them are benign tumors, and among them 70% are myxomas, the others are: fibroelastoma, rhabdomyoma, fibroma, angioma and lipoma.
  • Diagnosis is made by echocardiography TAC and MRI.
  • Whereas surgery is indicated in patients with benign tumors, or localised sarcomas, chemotherapy in those with widespread disease and radiotherapy and chemotherapy in lymphoma.
  • Prognosis is excellent in benign cardiac tumor.
  • [MeSH-minor] Angiography. Chemotherapy, Adjuvant. Combined Modality Therapy. Diagnosis, Differential. Echocardiography. Humans. Magnetic Resonance Imaging. Myocardium / pathology. Myxoma / diagnosis. Myxoma / pathology. Myxoma / surgery. Prognosis. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

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  • [Copyright] Copyright (c) 2010. Published by Elsevier Masson SAS.
  • (PMID = 20207301.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 28
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97. Murase K, Imai Y, Tachikawa R, Harada Y, Seo R, Kaji R, Takeshima Y, Hayashi M, Nishimura T, Tomii K, Katagami N, Ishihara K: [An autopsy case of racemose hemangioma of bronchial arteries associated with neovascularization from the chest wall after ligation and frequent embolizations]. Nihon Kokyuki Gakkai Zasshi; 2009 Jan;47(1):27-31
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  • [Title] [An autopsy case of racemose hemangioma of bronchial arteries associated with neovascularization from the chest wall after ligation and frequent embolizations].
  • We report an autopsied 33 year old pregnant woman with racemose hemangioma of the bronchial arteries.
  • She was first given a diagnosis of racemose hemangioma of the bronchial arteries at age 19 and underwent surgical ligation.
  • [MeSH-major] Bronchial Arteries / pathology. Embolization, Therapeutic / adverse effects. Hemangioma / pathology. Ligation / adverse effects. Neovascularization, Pathologic

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  • (PMID = 19198232.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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98. Cebesoy FB, Kutlar I, Aydin A: A rare mass formation of the vulva: giant cavernous hemangioma. J Low Genit Tract Dis; 2008 Jan;12(1):35-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare mass formation of the vulva: giant cavernous hemangioma.
  • OBJECTIVE: Vulvar hemangioma is an extremely rare pathology in adult women causing sexual dysfunction, pain, and cosmetic problems requiring therapeutic intervention.
  • MATERIALS AND METHODS: We present a case of an isolated giant vulvar cavernous hemangioma with a 2-year history that macroscopically seemed to be a vulvar varicosis but was actually detected at the end to be cavernous hemangioma in an adult patient with no history of other disease.
  • Histopathologic evaluation suggested cavernous hemangioma.
  • CONCLUSION: Hemangiomas can undergo spontaneous involution; thus, treatment may be reserved for those lesions of functional or psychological concern.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 18162811.001).
  • [ISSN] 1089-2591
  • [Journal-full-title] Journal of lower genital tract disease
  • [ISO-abbreviation] J Low Genit Tract Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Sun ZJ, Zhang L, Zhao YF: A postulated role for transcriptional regulator LMO2 in the proliferation and involution of hemangioma. Med Hypotheses; 2006;67(5):1230-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A postulated role for transcriptional regulator LMO2 in the proliferation and involution of hemangioma.
  • Hemangiomas are common benign vascular tumors distinctive for their perinatal presentation, rapid growth during the first year of life and subsequent slowly involution.
  • Many evidences suggest that hemangiomas are angiogenesis dependent entity.
  • Research also indicated that the endothelium of hemangioma shared molecular phenotype with blood cells.
  • It is logical to postulate that LMO2 may play a role in the pathogenesis, proliferating and involution of hemangioma.
  • Therapies directed against LMO2 have potential importance for treatment of hemangioma because of hemangioma's limited localization and the fact that LMO2-associated protein complexes could regulate angiogenesis.
  • [MeSH-major] DNA-Binding Proteins / physiology. Hemangioma / pathology. Metalloproteins / physiology. Neovascularization, Pathologic / pathology. Proto-Oncogene Proteins / physiology

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  • (PMID = 16793212.001).
  • [ISSN] 1532-2777
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / DNA-Binding Proteins; 0 / LIM Domain Proteins; 0 / LMO2 protein, human; 0 / Metalloproteins; 0 / Proto-Oncogene Proteins; 0 / Vascular Endothelial Growth Factor A; 103107-01-3 / Fibroblast Growth Factor 2
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100. Rarey K, Friberg TR: Indirect laser treatment and anti-VEGF therapy of a retinal angioma, with resolution of a large serous retinal detachment, macular exudates, and macular edema. Semin Ophthalmol; 2010 Jan-Mar;25(1-2):21-6
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  • [Title] Indirect laser treatment and anti-VEGF therapy of a retinal angioma, with resolution of a large serous retinal detachment, macular exudates, and macular edema.
  • PURPOSE: To report on a novel treatment strategy in an eye with a retinal angioma and macular edema METHODS: Wide-angle angiography was used to characterize the lesion and response to theraphy, while the treatment combined laser photocoagulation with the indirect laser delivery system, and intravitreal injections of pegaptanib and bevacizumab.
  • CONCLUSION: A combination of laser photocoagulation and anti-VEGF theraphy can be effective in the treatment of macular exudation and edema from a retinal angioma.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Hemangioma / therapy. Laser Coagulation. Macular Edema / therapy. Retinal Detachment / therapy. Retinal Neoplasms / therapy. Vascular Endothelial Growth Factor A / antagonists & inhibitors

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  • (PMID = 20507193.001).
  • [ISSN] 1744-5205
  • [Journal-full-title] Seminars in ophthalmology
  • [ISO-abbreviation] Semin Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Aptamers, Nucleotide; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / pegaptanib; 2S9ZZM9Q9V / Bevacizumab
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