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Items 1 to 82 of about 82
1. Filipovski V, Banev S, Janevska V, Dukova B: Granular cell tumor of the breast: a case report and review of literature. Cases J; 2009;2:8551

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the breast: a case report and review of literature.
  • Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast.
  • The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin.
  • The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound.

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  • (PMID = 19918386.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769456
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2. Khalid K, Alam MK, Al-Shakweer WA, Al-Teimi IN: Granular cell tumour of the ampulla of Vater. J Postgrad Med; 2005 Jan-Mar;51(1):36-8

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  • [Title] Granular cell tumour of the ampulla of Vater.
  • Granular cell tumour (GCT) is a rare soft tissue neoplasm commonly encountered in the head and neck region, skin and subcutaneous tissue.
  • The neoplasm constitutes less than 10% of all benign tumours of the extra-hepatic biliary tree.
  • We report a case of benign GCT involving the ampullary region in a 44-year-old Ethiopian male.
  • [MeSH-major] Ampulla of Vater / pathology. Common Bile Duct Neoplasms / diagnosis. Granular Cell Tumor / diagnosis

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  • (PMID = 15793336.001).
  • [ISSN] 0022-3859
  • [Journal-full-title] Journal of postgraduate medicine
  • [ISO-abbreviation] J Postgrad Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Eguia A, Uribarri A, Gay Escoda C, Crovetto MA, Martínez-Conde R, Aguirre JM: Granular cell tumor: report of 8 intraoral cases. Med Oral Patol Oral Cir Bucal; 2006 Aug;11(5):E425-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor: report of 8 intraoral cases.
  • Granular cell tumor (GCT) is an uncommon neoplasm of controversial origin that can appear in any corporal localization, including the orofacial region.
  • Although aggressive and malignant variants of this neoplasm have been described, most of GCTs are benign.
  • In spite of the amount of research, the etiology of this neoplasm remains unclear and its histogenesis and its possible muscular, connective or neural origin has been broadly debated.
  • The main clinicopathologic and diagnostic features of this neoplasm are reviewed and discussed.
  • [MeSH-major] Granular Cell Tumor / pathology. Mouth Neoplasms / pathology

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  • (PMID = 16878061.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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4. Pu RT, Yang J, Wasserman PG, Bhuiya T, Griffith KA, Michael CW: Does Hurthle cell lesion/neoplasm predict malignancy more than follicular lesion/neoplasm on thyroid fine-needle aspiration? Diagn Cytopathol; 2006 May;34(5):330-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does Hurthle cell lesion/neoplasm predict malignancy more than follicular lesion/neoplasm on thyroid fine-needle aspiration?
  • The diagnosis of an adequately sampled thyroid FNA is generally grouped into three categories: benign, malignant, and indeterminate.
  • The latter group usually includes follicular neoplasm, follicular lesion, and sometimes a more specific diagnosis such as Hurthle cell neoplasm or follicular lesion/neoplasm with Hurthle cell change.
  • Whether a FNA diagnosis of Hurthle cell lesion/neoplasm (HLN) denotes a worse clinical outcome than follicular lesion/neoplasm (FLN) remains controversial.
  • Upon excision, the FNA diagnosis of HLN group had 14 cases of goiter/nodular hyperplasia (16%), 46 cases of adenoma (12 follicular adenoma (14%) and 34 cases of Hurthle cell adenoma (39%)), and 27 cases of carcinoma (31%, 12 papillary carcinoma and 15 Hurthle cell carcinoma).
  • The FLN group had 74 cases of goiter/nodular hyperplasia (34.3%), 8 cases of Hashimoto thyroiditis (3.7%), 73 cases of follicular adenoma (33.8%), one case of granular cell tumor, and 60 cases of carcinoma (27.8%, 46 papillary carcinoma, 12 follicular carcinoma, and 1 Hurthle cell carcinoma and 1 parathyroid carcinoma) upon excision.
  • Hurthle cell carcinoma patients are typically older than patients with other cancer diagnoses (59 versus 44, P = 0.0077).
  • Males and older patients with a HLN FNA diagnosis carry a higher risk of Hurthle cell carcinoma upon thyroidectomy.

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  • (PMID = 16604553.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Abbas F, Memon A, Siddiqui T, Kayani N, Ahmad NA: Granular cell tumors of the urinary bladder. World J Surg Oncol; 2007;5:33
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  • [Title] Granular cell tumors of the urinary bladder.
  • BACKGROUND: Granular cell tumors (GCTs) are extremely rare lesions of the urinary bladder with only nine cases being reported in world literature of which one was malignant.
  • Generally believed to be of neural origin based on histochemical, immunohistochemical, and ultrastructural studies; they mostly follow a clinically benign course but are commonly mistaken for malignant tumors since they are solid looking, ulcerated tumors with ill-defined margins.
  • MATERIALS AND METHODS: We herein report two cases of GCTs, one benign and one malignant, presenting with gross hematuria in a 14- and a 47-year-old female, respectively.
  • The benign tumor was successfully managed conservatively with transurethral resection alone while for the malignant tumor, radical cystectomy, hysterectomy with bilateral salpingo-oophorectomy, anterior vaginectomy, plus lymph node dissection was done.
  • CONCLUSION: We recommend careful pathologic assessment for establishing the appropriate diagnosis and either a conservative or aggressive surgical treatment for benign or localized malignant GCT of the urinary bladder, respectively.
  • [MeSH-major] Cystoscopy / methods. Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Neoplasm Invasiveness / pathology. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biopsy, Needle. Emergency Service, Hospital. Female. Follow-Up Studies. Hematuria / diagnosis. Hematuria / etiology. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Nephrostomy, Percutaneous / methods. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17355632.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1828733
  • [General-notes] NLM/ Original DateCompleted: 20070810
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6. Yilmaz AD, Unlu RE, Orbay H, Sensoz O: Recurrent granular cell tumor: how to treat. J Craniofac Surg; 2007 Sep;18(5):1187-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent granular cell tumor: how to treat.
  • Granular cell tumor is an uncommon lesion usually located in the head and neck region (50%) with a female sex predominance.
  • Granular cell tumor has a peculiar clinical behavior ranging from clearly benign, locally aggressive, or manifestly malignant.
  • In this article, we present a case of recurrent benign granular cell tumor with the discussion of the treatment modalities.
  • The mass was excised two times at different centers and diagnosed as granular cell tumor after the pathologic examination.
  • [MeSH-major] Granular Cell Tumor / pathology. Head and Neck Neoplasms / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17912112.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Cserni G, Bori R, Sejben I: Vascular invasion demonstrated by elastic stain-a common phenomenon in benign granular cell tumors. Virchows Arch; 2009 Feb;454(2):211-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular invasion demonstrated by elastic stain-a common phenomenon in benign granular cell tumors.
  • Granular cell tumor is generally benign, but rare malignant cases have been documented.
  • Venous invasion was incidentally identified with the orcein elastic stain in an otherwise benign granular cell tumor (propositus case).
  • Four further benign granular cell tumors were also analyzed; venous invasion was discovered in three.
  • It is suggested that vascular invasion is not uncommon in granular cell tumors and should not lead to the classification of the tumor as malignant or atypical.
  • [MeSH-major] Blood Vessels / pathology. Elastic Tissue / pathology. Granular Cell Tumor / pathology. Staining and Labeling / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Lymphatic Metastasis. Male. Neoplasm Invasiveness

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  • (PMID = 19066954.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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8. Arevalo C, Maly B, Eliashar R, Gross M: Laryngeal granular cell tumor. J Voice; 2008 May;22(3):339-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal granular cell tumor.
  • Granular cell tumor (GCT) of the larynx is an uncommon, benign laryngeal neoplasm.
  • Abrikossoff first described the tumor in 1926 as myoblastoma.
  • The origin of this tumor has been debated in the literature.
  • Most of the authors believe that the tumor is of neural origin due to the characteristic immunohistochemical-staining pattern.
  • The authors describe two cases of laryngeal GCTs located in different sites with a review of the histological and clinical features, the differential diagnosis, and the treatment and the prognosis of the tumor.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Laryngeal Neoplasms / diagnosis. Vocal Cords

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  • (PMID = 17134875.001).
  • [ISSN] 0892-1997
  • [Journal-full-title] Journal of voice : official journal of the Voice Foundation
  • [ISO-abbreviation] J Voice
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Cheewakriangkrai C, Sharma S, Deeb G, Lele S: A rare female genital tract tumor: benign granular cell tumor of vulva: case report and review of the literature. Gynecol Oncol; 2005 May;97(2):656-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare female genital tract tumor: benign granular cell tumor of vulva: case report and review of the literature.
  • BACKGROUND: The granular cell tumor (GCT) of vulva is a rare female genital tract tumor.
  • Histologic examination of the tumor showed sheets and clusters of infiltrating tumor cells with morphologic features consistent with granular cell tumor.
  • CONCLUSION: Although benign and slow growing, it has a tendency for recurrence and can cause morbidity and mortality when presenting with multicentric or multiple organ involvement due to the lack of effective systemic therapy.
  • [MeSH-major] Granular Cell Tumor / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 15863174.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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10. Basu D, Sengupta A, Adhikari D, Dam A, Anwar T: Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report. J Indian Med Assoc; 2010 Mar;108(3):170, 175
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report.
  • Granular cell tumours are uncommon lesions, although the head and neck region accounts for approximately 50% of all lesions.
  • It is not clear whether or not granular cell tumour is a true neoplasm, a developmental anomaly, or a trauma-induced proliferation.
  • The basic cell of origin is now thought to be neural, although past reports frequently indicated an origin from striated muscle, or less frequently an origin from histiocytes, fibroblasts or pericytes.
  • More than a third of all granular cell tumours occur on the lingual dorsum, usually as a sessile, painless, somewhat firm, immoveable nodule less than 1.5 cm in greatest diameter.
  • As most of the granular cell tumours are benign, surgical excision of the lesion is the treatment of choice.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21043356.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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11. Angiero F, Crippa R, Stefani M: Granular cells tumour in the oral cavity: report of eleven cases treated with laser surgery. Minerva Stomatol; 2006 Jul-Aug;55(7-8):423-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cells tumour in the oral cavity: report of eleven cases treated with laser surgery.
  • METHODS: Between 1999 and 2004, 11 patients (6 females, 5 males; age range 28-66 years) were treated for tumours classified as being of neural origin; they were all myoblastomas or granular cells tumours (ex Abrikossoff tumour).
  • CONCLUSIONS: Granular cell tumour is a benign neoplasm with a tendency to relapse if not completely removed.
  • [MeSH-major] Granular Cell Tumor / surgery. Laser Therapy. Mouth Neoplasms / surgery

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  • (PMID = 17041542.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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12. Arican O, Ciralik H, Sasmaz S: Multiple plaques on the back: S-100 negative benign granular cell tumor. J Dermatol; 2005 Jul;32(7):585-8
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  • [Title] Multiple plaques on the back: S-100 negative benign granular cell tumor.
  • Granular cell tumor is a rarely seen disease characterized by a gradually developing nodular lesion, which is difficult to diagnose.
  • The tumor usually appears in the 4th-6th decades of life, more frequently in women and blacks, and has a multifocal location in 10-25% of the cases.
  • The present paper describes an 18-year-old female patient with benign granular cell tumor.
  • This rarely seen type of tumor was S-100 negative and has been detected in biopsies taken from multiple asymptomatic plaques and maculopapular lesions.
  • [MeSH-major] Granular Cell Tumor / pathology. S100 Proteins / analysis. Skin Neoplasms / pathology

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  • (PMID = 16335876.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / S100 Proteins
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13. Lauwers K, Bestman TJ, Bergmans G, Molderez C: Granular cell tumour of the male breast. Acta Chir Belg; 2008 Jan-Feb;108(1):112-4
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  • [Title] Granular cell tumour of the male breast.
  • Granular cell tumour (GCT) is a rare neoplasm that can be found in multiple sites throughout the body.
  • In general, it appears as a singular benign lesion, although it can be multi-focal and rare cases with malignant behaviour have been reported.
  • We report a rare case of granular cell tumour of the nipple in the male breast, treated by wide local excision.
  • [MeSH-major] Breast Neoplasms, Male / surgery. Granular Cell Tumor / surgery

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  • (PMID = 18411585.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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14. Józefowicz-Korczyńska M, Kozłowski Z, Pietruszewska W, Lukomski M: [Granular-cell myoblastoma of the larynx clinical analysis]. Otolaryngol Pol; 2005;59(6):807-12

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  • [Title] [Granular-cell myoblastoma of the larynx clinical analysis].
  • Clinical date of four cases of granular-cell myoblastoma tumors arising in the larynx and clinical analysis of 11 cases published in Polish literature were reviewed and studied.
  • Granular-cell tumor is a rare, usually benign neoplasm that can occur in various part of the body.
  • The larynx tumor is accounting for 7% to 10% of all reported cases.
  • The tumor was generally presented in patients in their forth and fifth decade.
  • Clinically the tumors were considered benign.
  • In one case because the location and size of the tumor subtotal laryngectomy was necessary to conduct.
  • [MeSH-major] Granular Cell Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 16521442.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 18
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15. Devi K, Mohanty P, Mohanty L, Bhuyan P, Mishra A, Hazra K: Cytodiagnosis of granular cell tumor: a case report. Indian J Pathol Microbiol; 2007 Jan;50(1):61-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytodiagnosis of granular cell tumor: a case report.
  • Fine needle aspiration diagnosis was benign granular cell tumor which was confirmed by histopathology.
  • Since it is an uncommon tumor, of controversial histogenesis, it is being reported here.
  • [MeSH-major] Granular Cell Tumor / diagnosis

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  • (PMID = 17474262.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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16. Rego A, Amado J, Esteves I, Almeida J, Furtado A, Couceiro A, Moura e Sá J: [Endobronchial granular cell tumor - what approach to take]. Rev Port Pneumol; 2006 Jul-Aug;12(4):463-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endobronchial granular cell tumor - what approach to take].
  • [Transliterated title] Tumor de células granulares endobrônquico - Como abordamos?
  • Granular cell tumor is a mesenchymal neoplasm almost always benign, with tendency to recurrence.
  • The authors describe two cases of endobronchial granular cell tumours, discuss the particularities of this pathology as well as the treatment options, with particular attention to the use of endobronchial excision and criotherapy.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / therapy. Granular Cell Tumor / diagnosis. Granular Cell Tumor / therapy

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  • (PMID = 16969575.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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17. Chelly I, Bellil K, Mekni A, Bellil S, Belhadjsalah M, Kchir N, Haouet S, Zitouna MM: Malignant granular cell tumor of the abdominal wall. Pathologica; 2005 Jun;97(3):130-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant granular cell tumor of the abdominal wall.
  • The granular cell tumor is an uncommon tumor that usually appears as a solitary small nodular growth and runs a benign course.
  • The authors report a case of malignant granular cell tumor which was arising in anterior abdominal wall of a 67-year-old woman.
  • [MeSH-major] Abdominal Neoplasms / pathology. Abdominal Wall / pathology. Granular Cell Tumor / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Fatal Outcome. Female. Humans. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Postoperative Complications. Pulmonary Embolism / complications

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  • (PMID = 16259279.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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18. K C S, Kouzu T, Hishikawa E: Multiple granular cell tumor of the esophagus treated endoscopically. JNMA J Nepal Med Assoc; 2007 Jan-Mar;46(165):40-3
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  • [Title] Multiple granular cell tumor of the esophagus treated endoscopically.
  • Granular cell tumor (GCT) of esophagus is a rare lesion, usually found incidentally during upper gastrointestinal endoscopic examination undertaken for another reasons.
  • The origin of this neoplasm is still unclear but no organ seems to be immune to this neoplasm.
  • Although most of the lesions are benign, few reports of malignant GCT, synchronous as well as metachronous, are also reported.

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  • (PMID = 17721562.001).
  • [ISSN] 0028-2715
  • [Journal-full-title] JNMA; journal of the Nepal Medical Association
  • [ISO-abbreviation] JNMA J Nepal Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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19. Wright NA, Thomas CG, Calame A, Cockerell CJ: Granular cell atypical fibroxanthoma: case report and review of the literature. J Cutan Pathol; 2010 Mar;37(3):380-5
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  • [Title] Granular cell atypical fibroxanthoma: case report and review of the literature.
  • We present a case of granular cell atypical fibroxanthoma of the scalp.
  • The neoplasm occurred as a tender nodule on the frontal scalp of an 82-year-old Caucasian man.
  • Histology demonstrated a diffuse proliferation of atypical epithelioid cells with abundant granular cytoplasm.
  • The granular cell phenotype has been observed in other cutaneous neoplasms including granular cell tumors, dermatofibromas, dermatofibrosarcoma protuberans, fibrous papules, basal cell carcinomas, leiomyosarcomas, angiosarcomas and primitive polypoid granular cell tumors.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology
  • [MeSH-minor] Aged, 80 and over. Biomarkers, Tumor. Disease-Free Survival. Humans. Immunohistochemistry. Male. Scalp / metabolism. Scalp / pathology. Scalp / surgery. Treatment Outcome

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  • (PMID = 19341433.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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20. Andrade ES, Filho JR, Rocha NS, Neto IC, Camargo IB: Isolated intra-oral granular cell tumor: report of two cases and review of the literature. Acta Odontol Latinoam; 2010;23(2):99-104

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolated intra-oral granular cell tumor: report of two cases and review of the literature.
  • Granular cell tumor (GCT) is a relatively uncommon lesion occurring in almost any part of the body, including the orofacial region.
  • Although aggressive and malignant variants of this neoplasm have been described, most GCTs are benign.
  • The tumor generally occurs in middle-aged or older adults.
  • As most granular cell tumors are benign, surgical excision of the lesion is the treatment of choice.
  • Differential diagnoses include fibrous hyperplasia, minor salivary gland tumor condyloma acuminatum and neurilemmoma.
  • The main clinical pathology and diagnostic features of this neoplasm are reviewed and discussed.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21053681.001).
  • [ISSN] 0326-4815
  • [Journal-full-title] Acta odontológica latinoamericana : AOL
  • [ISO-abbreviation] Acta Odontol Latinoam
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Argentina
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21. Chaudhry IH, Calonje E: Dermal non-neural granular cell tumour (so-called primitive polypoid granular cell tumour): a distinctive entity further delineated in a clinicopathological study of 11 cases. Histopathology; 2005 Aug;47(2):179-85
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  • [Title] Dermal non-neural granular cell tumour (so-called primitive polypoid granular cell tumour): a distinctive entity further delineated in a clinicopathological study of 11 cases.
  • AIMS: Cutaneous and soft tissue granular cell tumour is a well-characterized benign neoplasm of neural origin.
  • However, there remains a subcategory of granular cell tumour, first described by Le Boit as 'primitive polypoid granular cell tumour', that shows no obvious line of differentiation.
  • METHODS AND RESULTS: Eleven cases of dermal non-neural granular cell tumour were retrieved from one of the authors referral archives (E.C.) and both the histology and immunohistochemistry reviewed.
  • The tumours were composed of elongated spindle-shaped to polygonal or round cells with prominent granular cell change, and tumour nuclei showing mild focal atypia to rare moderate atypia.
  • [MeSH-major] Granular Cell Tumor / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Biomarkers, Tumor / analysis. Child. Factor XIIIa / analysis. Female. Humans. Immunohistochemistry. Lysosomes / immunology. Male. Middle Aged

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  • (PMID = 16045779.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD68 antigen, human; EC 2.3.2.13 / Factor XIIIa
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22. Persaud R, Tudge S, Amonoo-Kuofi K, Beale T, O'Flynn P: Parapharyngeal granular cell tumour: a unique surgical challenge. J Laryngol Otol; 2005 Jan;119(1):68-70
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  • [Title] Parapharyngeal granular cell tumour: a unique surgical challenge.
  • A granular cell tumour is a rare lesion of probable nerve sheath origin.
  • It is typically benign but up to seven per cent may be malignant.
  • The authors report a case of a 49-year-old African woman with an oro-naso-parapharyngeal granular cell neoplasm causing mild dysphagia.
  • [MeSH-major] Granular Cell Tumor / surgery. Pharyngeal Neoplasms / surgery

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  • (PMID = 15807973.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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23. Blacksin MF, White LM, Hameed M, Kandel R, Patterson FR, Benevenia J: Granular cell tumor of the extremity: magnetic resonance imaging characteristics with pathologic correlation. Skeletal Radiol; 2005 Oct;34(10):625-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the extremity: magnetic resonance imaging characteristics with pathologic correlation.
  • OBJECTIVE: The purpose of this study is to delineate the magnetic resonance (MR) appearance of a granular cell tumor (GrCT) of the extremity and to correlate the imaging appearance with the microscopic findings.
  • DESIGN AND PATIENTS: A retrospective review of five patients with a histopathologic diagnosis of GrCT and pre-operative MR imaging of the neoplasm was done.
  • RESULTS: The benign subtype of GrCT is usually isointense or brighter than muscle on T1-weighted sequences, round or oval in shape, superficial in location, and 4 cm or less in size.
  • On T2-weighted sequences, benign lesions may demonstrate a high peripheral signal, as well as a central signal intensity that is isointense to muscle or suppressed fat.
  • A significant stromal component in the tumor and, hypothetically, a ribbon-like arrangement of tumor cells may influence the signal intensity demonstrated on the T1 and T2-weighted sequences.
  • CONCLUSION: Benign GrCT has imaging characteristics which may distinguish this tumor from other soft tissue neoplasms, as well as the malignant type of this tumor.
  • [MeSH-major] Foot Diseases / pathology. Granular Cell Tumor / pathology. Hand / pathology. Shoulder / pathology. Soft Tissue Neoplasms / pathology. Thigh / pathology

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  • (PMID = 16003548.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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24. Vered M, Carpenter WM, Buchner A: Granular cell tumor of the oral cavity: updated immunohistochemical profile. J Oral Pathol Med; 2009 Jan;38(1):150-9
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  • [Title] Granular cell tumor of the oral cavity: updated immunohistochemical profile.
  • BACKGROUND: Granular cell tumor (GCT) is a benign lesion that occurs at different body sites with preponderance to the oral cavity.
  • It is generally believed to be of schwann cell/neural cell origin.
  • The granular cells demonstrated a wide array of cytological features in terms of cell shape and position of the nucleus.
  • Granular cells were usually found to be strongly and diffusely positive for p75, vimentin, calretinin and NKI/C3, inhibin-alpha, PGP9.5, and S-100.
  • CONCLUSIONS: Immunoreactivity of the granular cells to a broad panel of antibodies that characterize different tissues does not confirm any particular cell type for the histogenetic origin of GCTs.
  • Furthermore, GCTs could be regarded as lesions that reflect a local metabolic or reactive change rather than a true neoplasm.
  • [MeSH-major] Granular Cell Tumor / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Biomarkers, Tumor / analysis. Calbindin 2. Cell Nucleus / pathology. Cell Shape. Child. Female. Humans. Immunohistochemistry. Inhibins / analysis. Macrophages / pathology. Male. Membrane Glycoproteins. Middle Aged. Nerve Tissue Proteins / analysis. Receptors, Nerve Growth Factor / analysis. S100 Calcium Binding Protein G / analysis. S100 Proteins / analysis. Tongue Neoplasms / pathology. Ubiquitin Thiolesterase / analysis. Vimentin / analysis. Young Adult. gp100 Melanoma Antigen

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  • (PMID = 19192059.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / CD68 antigen, human; 0 / Calbindin 2; 0 / Membrane Glycoproteins; 0 / NGFR protein, human; 0 / Nerve Tissue Proteins; 0 / PMEL protein, human; 0 / Receptors, Nerve Growth Factor; 0 / S100 Calcium Binding Protein G; 0 / S100 Proteins; 0 / Vimentin; 0 / gp100 Melanoma Antigen; 0 / inhibin-alpha subunit; 57285-09-3 / Inhibins; EC 3.1.2.15 / UCHL1 protein, human; EC 3.1.2.15 / Ubiquitin Thiolesterase
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25. Sidwell RU, Rouse P, Owen RA, Green JS: Granular cell tumor of the scrotum in a child with Noonan syndrome. Pediatr Dermatol; 2008 May-Jun;25(3):341-3
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  • [Title] Granular cell tumor of the scrotum in a child with Noonan syndrome.
  • Granular cell tumor is a rare neoplasm thought to be of neural origin, composed of cells with distinctive granular cytoplasm.
  • Granular cell tumors most often arise on the tongue, but can occur at any body site, and therefore initial presentation to dermatologists is common.
  • We report a granular cell tumor of the scrotum in a child with Noonan syndrome, known to have a mutation in the PTPN11 gene.
  • No previous reports of granular cell tumor of the scrotum in a child are found.
  • The tumor is usually benign; however, it can have a high local recurrence rate (variable between 2% and 50% dependent on whether initial excision is complete and on the occurrence of an infiltrative growth pattern) and therefore long-term follow-up is necessary.
  • This case highlights the occurrence of granular cell tumor, a diagnosis not to be missed by the dermatologist.
  • In addition, we postulate the possible role of PTPN11 mutations in the development of granular cell tumor.
  • [MeSH-major] Genital Neoplasms, Male / genetics. Granular Cell Tumor / genetics. Mutation. Noonan Syndrome / complications. Protein Tyrosine Phosphatase, Non-Receptor Type 11 / genetics

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  • (PMID = 18577039.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.3.48 / PTPN11 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 11
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26. Daniels JS: Granular cell tumour of tongue: A case report. Saudi Dent J; 2009 Jul;21(2):75-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of tongue: A case report.
  • Granular cell tumour, also known as Abrikossoff tumour, is a relatively uncommon benign neoplasm, which is more commonly found in females in the 4th to 6th decades of life even though it can occur in all ages.
  • Intraoral lesions represent about 70% of the granular cell tumours of the head and neck, and account for 1/3 of all cases affecting the whole body.
  • Although majority of granular cell tumours are benign, some are clinically aggressive and a few frankly malignant forms have been reported.
  • Some benign lesions exhibit surface ulcerations and this clinical appearance, combined with the overlying pseudoepitheliomatous hyperplasia, seen histologically, may lead to misdiagnosis of malignancy if adequate biopsy material was not taken.
  • A case of granular cell tumour which occurred on the midline area of the dorsum of the posterior 1/3 of the tongue is reported in a 20-year-old female patient.

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  • (PMID = 23960463.001).
  • [ISSN] 1013-9052
  • [Journal-full-title] The Saudi dental journal
  • [ISO-abbreviation] Saudi Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3722994
  • [Keywords] NOTNLM ; Dorsum of posterior one-third of tongue / Granular cell tumour / Lingual thyroid / Pseudoepitheliomatous hyperplasia / Squamous cell carcinoma of tongue
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27. Sargenti-Neto S, Brazão-Silva MT, do Nascimento Souza KC, de Faria PR, Durighetto-Júnior AF, Loyola AM, Cardoso SV: Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions. Br J Oral Maxillofac Surg; 2009 Jan;47(1):62-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions.
  • Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue.
  • [MeSH-major] Granular Cell Tumor / pathology. Lip Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Genital Neoplasms, Female / surgery. Humans. Neoplasm Recurrence, Local. Perineum / pathology. Perineum / surgery

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  • (PMID = 18976838.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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28. Kavanagh DO, O'Riain C, Ridgway PF, Neary P, Crotty TC, Geoghegan JG, Traynor O: Radical pancreaticoduodenectomy for benign disease. ScientificWorldJournal; 2008;8:1156-67
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  • [Title] Radical pancreaticoduodenectomy for benign disease.
  • Preoperative histological confirmation of malignancy is frequently unavailable and some patients will subsequently be found to have benign disease.
  • Here, we review our experience with Whipple's procedure for patients ultimately proven to have benign disease.
  • In eight cases, the final histology was benign (7.1%).
  • One additional patient was known to have benign disease at resection.
  • The pathological diagnosis included benign biliary stricture (two), chronic pancreatitis (two), choledochal cyst (one), inflammatory pseudotumour (one), cystic duodenal wall dysplasia (one), duodenal angiodysplasia (one), and granular cell neoplasm (one).
  • Despite recent advances in diagnostic imaging, 8% of the patients undergoing Whipple's procedure had benign disease.
  • Endoscopic ultrasound-guided fine needle aspirate (EUS-FNA) may reduce the need for Whipple's operation in benign pancreaticobiliary disease in the future.

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  • (PMID = 19030761.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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29. Narra SL, Tombazzi C, Datta V, Ismail MK: Granular cell tumor of the esophagus: report of five cases and review of the literature. Am J Med Sci; 2008 May;335(5):338-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the esophagus: report of five cases and review of the literature.
  • Granular cell tumor (GCT) is an uncommon esophageal neoplasm.
  • The usual course of GCTs is benign.
  • [MeSH-major] Esophageal Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 18480648.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Popovska S: [Granular cell tumor of the breast--review of the literature and research for a period of 5 years]. Khirurgiia (Sofiia); 2006;(1):53-5
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  • [Title] [Granular cell tumor of the breast--review of the literature and research for a period of 5 years].
  • Granular cell tumor is relatively rare neoplasm, and always benign in its prognostic behavior.
  • Location of this tumor in the breast presents serious problems for differential diagnosis, both from a clinical point of view and at gross pathologic examination, because of its resemblance to carcinoma.
  • Most granular cell tumors appear to be derived from Schwann cells of peripheral nerves, but many different lesions in the breast show granular cell changes.
  • The authors describe four typical cases of breast granular cell tumors that occurred in patients of different ages, and discuss the most important problems concerning this lesion.
  • [MeSH-major] Breast Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 18771140.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Bulgaria
  • [Number-of-references] 11
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31. Singhi AD, Montgomery EA: Colorectal granular cell tumor: a clinicopathologic study of 26 cases. Am J Surg Pathol; 2010 Aug;34(8):1186-92
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  • [Title] Colorectal granular cell tumor: a clinicopathologic study of 26 cases.
  • Granular cell tumor (GCT) is commonly located in the subcutaneous tissue and oral cavity, and uncommon in the gastrointestinal tract, in which the majority arises in the esophagus with over-representation in African Americans (AA).
  • Although GCTs were benign tumors in this series, if incompletely excised regrowth of the lesion may occur and therefore, follow-up may be warranted.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biopsy. Colectomy. Colonoscopy. Female. Humans. Immunohistochemistry. Intestinal Mucosa / pathology. Male. Middle Aged. Neoplasm Invasiveness. Prognosis. S100 Proteins / analysis

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  • (PMID = 20661017.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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32. Sartorius C, Plechata B, Luis W, Kempf HG: [Granular cell tumor -- a rare tumor lesion of submandibular gland origin]. Laryngorhinootologie; 2005 Oct;84(10):755-7

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  • [Title] [Granular cell tumor -- a rare tumor lesion of submandibular gland origin].
  • [Transliterated title] Granularzelltumor, ein seltener Tumor der Glandula submandibularis.
  • RATIONALE: Granular cell tumors are rare entities with manifestations in nearly all organ systems.
  • CASE REPORT: We report a 54 years old female patient with a painless submandibular tumor lesion.
  • Using a submandibular approach the tumor was totally removed with the submandibular gland.
  • Histologically a benign granular cell tumor was diagnosed.
  • The clinical follow-up for about 3 years was without complications or tumor recidive.
  • CONCLUSIONS: A differential diagnosis of a submandibular mass is the rare manifestation of a benign granular cell tumor.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Submandibular Gland Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Middle Aged. S100 Proteins / analysis. Submandibular Gland / pathology. Submandibular Gland / surgery. Vimentin / analysis

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  • (PMID = 16231244.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / Vimentin
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33. Torrijos-Aguilar A, Alegre-de Miquel V, Pitarch-Bort G, Mercader-García P, Fortea-Baixauli JM: [Cutaneous granular cell tumor: a clinical and pathologic analysis of 34 cases]. Actas Dermosifiliogr; 2009 Mar;100(2):126-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cutaneous granular cell tumor: a clinical and pathologic analysis of 34 cases].
  • [Transliterated title] Tumor de células granulares cutáneo: análisis clínico-patológico de treinta y cuatro casos.
  • BACKGROUND: Granular cell tumor (GCT), also known as Abrikossoff tumor, is an uncommon benign neoplasm, probably of neural origin derived from Schwann cells.
  • OBJECTIVES: We aimed to analyze the clinical, histologic, and immunohistochemical characteristics associated with this tumor and to determine whether these findings correspond to those reported to date in the literature.
  • METHODS: In this retrospective study of 34 patients with histologic diagnosis of GCT, we analyzed clinical characteristics (site, age, sex, duration, and suspected diagnosis), histological findings (border, cell atypia and mitoses, involvement of adnexal structures, pseudoepitheliomatous hyperplasia, and presence of the recently described pustulo-ovoid bodies), and immunohistochemical findings (S-100 staining in 16 randomly selected cases).
  • CONCLUSIONS: Our series confirms the characteristics described previously for GCT, except for certain peculiarities, and supports the presence of pustulo-ovoid bodies as an additional histologic finding for diagnosis of this tumor.
  • [MeSH-major] Granular Cell Tumor / epidemiology. Mouth Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor. Child. Child, Preschool. Cytoplasmic Granules / ultrastructure. Diagnosis, Differential. Female. Fibroma / diagnosis. Humans. Male. Middle Aged. Retrospective Studies. Skin Neoplasms / chemistry. Skin Neoplasms / diagnosis. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology. Staining and Labeling. Young Adult

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  • (PMID = 19445877.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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34. Caltabiano R, Cappellani A, Di Vita M, Lanzafame S: The unique simultaneous occurrence of a squamous cell carcinoma and a granular cell tumor of the tongue at the same site: a histological and immunohistochemical study. J Craniofac Surg; 2008 Nov;19(6):1691-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The unique simultaneous occurrence of a squamous cell carcinoma and a granular cell tumor of the tongue at the same site: a histological and immunohistochemical study.
  • We report a case of a 47-year-old man with a granular cell tumor (GCT) of the tongue colocalized with a squamous cell carcinoma.
  • Furthermore, we performed an immunohistochemical analysis with p63 to distinguish pseudoepitheliomatous hyperplasia from invasive squamous cell carcinoma.
  • Clinicians and pathologists must be made aware of this potential diagnostic pitfall so that the workup of a tongue lesion does not end prematurely with a benign diagnosis of granular cell tumor with overlying pseudoepitheliomatous hyperplasia.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Cell Nucleus / ultrastructure. Cytoplasm / ultrastructure. Epithelium / pathology. Follow-Up Studies. Humans. Hyperplasia. Immunohistochemistry. Male. Membrane Proteins / analysis. Middle Aged. Mouth Mucosa / pathology. Neoplasm Invasiveness. S100 Proteins / analysis

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  • (PMID = 19098584.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Proteins; 0 / S100 Proteins
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35. Veit AC, Painter JT, Miller RA, Hardisty JF, Dixon D: Characterization of uterine granular cell tumors in B6C3F1 mice: a histomorphologic, immunohistochemical, and ultrastructural study. Vet Pathol; 2008 Sep;45(5):654-62
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  • [Title] Characterization of uterine granular cell tumors in B6C3F1 mice: a histomorphologic, immunohistochemical, and ultrastructural study.
  • The granular cell tumor is most often a benign neoplasm of uncertain origin.
  • Four uterine granular cell tumors in control and treated female B6C3F1 mice were identified in chronic studies at the National Toxicology Program.
  • The main histomorphologic feature of tumor cells was the presence of abundant cytoplasmic eosinophilic granules that stained positive for periodic acid-Schiff with diastase resistance.
  • The characteristics of these uterine granular cell tumors were suggestive of a myogenic origin.
  • [MeSH-major] Granular Cell Tumor / veterinary. Uterine Neoplasms / veterinary

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  • (PMID = 18725470.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z99 ES999999
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS103826; NLM/ PMC2691646
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36. Kondo T, Kajimoto S, Okuda H, Toma H, Tanabe K: A case of granular cell tumor of the bladder successfully managed with extraperitoneal laparoscopic surgery. Int J Urol; 2006 Jun;13(6):827-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of granular cell tumor of the bladder successfully managed with extraperitoneal laparoscopic surgery.
  • Granular cell tumor is a benign neoplasm which frequently occurs in the oral cavity, skin, and subcutaneous tissue.
  • Granular cell tumor of the bladder is an extremely rare disease, and only nine cases have been reported.
  • We present here an additional case of granular cell tumor occurring in the bladder.
  • Unlike the other tumors reported, this tumor extruded into the Retzius' cavity.
  • Therefore, the tumor was successfully excised through extraperitoneal laparoscopic surgery.
  • The small tumor located in Retzius' cavity could be managed with extraperitoneal laparoscopic surgery.
  • [MeSH-major] Granular Cell Tumor / therapy. Laparoscopy. Urinary Bladder Neoplasms / therapy

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  • (PMID = 16834673.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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37. Di Cicilia R, Castellucci P, Nannini M, Balbi T, Zannetti G, Fanti S, Biasco G, Pantaleo MA: Unusual finding of benign Abrikossoff tumor by F-18 FDG-PET mimicking melanoma recurrence. Clin Nucl Med; 2009 Oct;34(10):696-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual finding of benign Abrikossoff tumor by F-18 FDG-PET mimicking melanoma recurrence.
  • Granular cell tumor of Abrikossoff is a rare neoplasm that may occur in a wide variety of cutaneous and visceral sites.
  • Granular cell tumor generally shows benign behavior.
  • We present a case of F-18 fluorodeoxyglucose positron emission tomography in Abrikossoff tumor, suggesting that F-18 fluorodeoxyglucose positron emission tomography may have a potential role in the management of this neoplasm.
  • [MeSH-major] Fluorodeoxyglucose F18. Granular Cell Tumor / radionuclide imaging. Melanoma / radionuclide imaging. Positron-Emission Tomography

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  • (PMID = 19893405.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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38. Scala WA, Fernandes AM, Duprat Ade C, Costa HO: Granular cell tumor of the larynx in children: a case report. Braz J Otorhinolaryngol; 2008 Sep-Oct;74(5):780-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the larynx in children: a case report.
  • The granular cell tumor (GCT) is an uncommon neoplasm, with slow progression, usually benign, that can be found in any organ.
  • Among the major theories of origin and based on the strongest evidence, the most accepted one is that the tumor stems from neuronal tissue.
  • [MeSH-major] Granular Cell Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 19082363.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 13
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39. Patti R, Almasio PL, Di Vita G: Granular cell tumor of stomach: a case report and review of literature. World J Gastroenterol; 2006 Jun 7;12(21):3442-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of stomach: a case report and review of literature.
  • Granular cell tumor (GCT) was described for the first time by Abrikosoff in 1926.
  • It is a relatively rare neoplasm that may occur at many sites, but most commonly in the skin or soft tissues.
  • Although GCTs are usually clinically and histologically benign, some malignant cases have been reported.
  • A correct preoperative diagnosis of this tumor can only be made in 50% of all patients and it is always based on endoscopic biopsy.
  • In this study, the authors reported a case of a 49-year-old woman with a solitary granular cell tumor of the stomach with infiltrative pattern, successfully treated with surgical resection.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery

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  • (PMID = 16733867.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC4087881
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40. Hong R, Lim SC: Granular cell tumor of the cecum with extensive hyalinization and calcification: a case report. World J Gastroenterol; 2009 Jul 14;15(26):3315-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the cecum with extensive hyalinization and calcification: a case report.
  • A granular cell tumor (GCT) is a benign neoplasm of unclear histogenesis that is generally believed to be of nerve sheath origin.
  • In addition to the tumor, endoscopic examination revealed the presence of a 5-mm-polyp in the descending colon and multiple tiny polyps in the sigmoid colon and rectum.
  • Histological examination demonstrated a cecal tumor 1.5 cm x 1.0 cm x 0.7 cm with a hard consistency; in cut sections, mixed cells with yellowish and whitish portions were seen.
  • The tumor was located between the mucosa and subserosa, and was composed of plump histiocyte-like tumor cells with abundant granular eosinophilic cytoplasm, which were immunoreactive for S-100 protein, vimentin, neuron-specific enolase, inhibin-alpha and calretinin.
  • The tumor showed extensive hyalinization and focal dystrophic calcification.
  • Immunohistochemical profiles did not confirm any particular cell type for the histogenetic origin of the GCT, including a nerve sheath origin.
  • Extensive hyalinization and calcification showing involution of tumor cells suggest benign clinical behavior of GCT.
  • [MeSH-major] Calcinosis / pathology. Cecum / pathology. Granular Cell Tumor / pathology. Hyalin / metabolism
  • [MeSH-minor] Biomarkers, Tumor. Calbindin 2. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / pathology. Humans. Male. Middle Aged. Phosphopyruvate Hydratase. S100 Calcium Binding Protein G. S100 Proteins. Vimentin

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  • (PMID = 19598311.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / S100 Proteins; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
  • [Other-IDs] NLM/ PMC2710791
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41. Rodriguez y Baena R, Di Ieva A, Colombo P, Collini P, Navarria P, Scorsetti M, Gaetani P, Santoro A: Intramedullary astrocytoma with granular cell differentiation. Neurosurg Rev; 2007 Oct;30(4):339-43; discussion 343

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramedullary astrocytoma with granular cell differentiation.
  • Granular cell astrocytomas are uncommon tumors of the central nervous system (CNS) of which no cases have been documented in the spinal cord.
  • This variant of glioma should not be confused with benign granular cell tumor which, although rare, has been well characterized in the spinal cord.
  • At surgery, the tumor was found to be infiltrating a posterior column with no dural attachment.
  • The histological diagnosis was astrocytoma with granular cell differentiation.
  • In addition to documenting a unique example of intramedullary granular cell astrocytoma, we review the literature to investigate differences from other tumors with granular changes described in the spinal cord.

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  • (PMID = 17483971.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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42. Faquin WC, Cibas ES, Renshaw AA: "Atypical" cells in fine-needle aspiration biopsy specimens of benign thyroid cysts. Cancer; 2005 Apr 25;105(2):71-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "Atypical" cells in fine-needle aspiration biopsy specimens of benign thyroid cysts.
  • Most are benign nodules with degenerative changes in a multinodular goiter.
  • Fine-needle aspiration biopsy (FNAB) specimens from these cystic nodules usually are easily interpreted as benign.
  • However, occasionally, cells with atypical features are encountered, increasing the possibility of a cystic malignant neoplasm.
  • To the authors' knowledge, the microscopic features of these benign cells, presumed to be of cyst-lining origin, have not been well described to date.
  • Seventy-five specimens with subsequent histologic correlation showing a benign cystic thyroid nodule were selected for study.
  • However, in 29% of these specimens, a papillary or Hurthle cell neoplasm could not be excluded.
  • The most common features were cohesive flat sheets (84%), distinct cell borders (96%), nuclear enlargement (92%), nuclear grooves (79%), dense granular cytoplasm (79%), small distinct nucleoli (85%), fine chromatin (87%), and elongate to spindled cytomorphology (57%).
  • In contrast to the atypical cells from benign cysts, cystic papillary carcinomas lacked the repair-like spindled cytomorphology, and showed nuclear crowding (100%), as well as papillary microarchitecture (50%), and rare intranuclear pseudoinclusions (42%).
  • CONCLUSIONS: Atypical cyst-lining cells were found to have characteristic features (e.g., distinct cell borders, elongated shape, eosinophilic cytoplasm, and distinct nucleoli) and lacked nuclear crowding, intranuclear pseudoinclusions, and papillary architecture that, in many specimens, allowed them to be recognized as benign.
  • The authors recommended that the subset of cells with the characteristic features described in the current study be reported as "consistent with benign cyst lining cells".

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  • [Copyright] 2005 American Cancer Society.
  • [CommentIn] Cancer. 2006 Feb 25;108(1):72; author reply 73 [16400633.001]
  • (PMID = 15662703.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Sokolova IA, Hes O, Michal M, Matsko DE: [Small-cell variant of renal oncocytoma]. Arkh Patol; 2007 Sep-Oct;69(5):34-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Small-cell variant of renal oncocytoma].
  • Renal oncocytoma is a distinct benign tumor accounting for approximately 3-5% of all renal tumors.
  • This neoplasm is easily recognizable in its classic form: there are polygonal cells with abundant granular eosinophilic cytoplasm filled with mitochondria.
  • The tumor cells are arranged in nests and tubular pattern.
  • The term "small-cell variant of renal oncocytoma" was proposed for these cases.
  • The unusual extensive small-cell component of the tumor may represent a potential diagnostic pitfall for primary or metastatic malignant small cell tumors.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Small Cell / pathology. Cytoplasm / pathology. Kidney Neoplasms / pathology. Mitochondria / pathology
  • [MeSH-minor] Aged. Female. Humans. Neoplasm Metastasis

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  • (PMID = 18074818.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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44. Marolleau F, Baert F, Mertens V, Ghillebert G: Abrikossoff cell tumor of the oesophagus: a case report and review of the literature. Acta Clin Belg; 2008 Jul-Aug;63(4):273-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abrikossoff cell tumor of the oesophagus: a case report and review of the literature.
  • Abrikossoff tumours or granular cell tumours are rare and usually benign tumours.
  • The macroscopic appearance is typical (yellow, firm, well circumscribed submucosal neoplasm-like with reduced vascular patterns) but due to the rarity of this lesion, it can be mistaken with other similar lesions.
  • This is the report of a case of a 47-year-old female with a granular cell tumour of the distal oesophagus.
  • In this case, the Abrikossoff tumour is clinically, radiologically en histologically benign.
  • [MeSH-major] Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / therapy. Granular Cell Tumor / diagnosis. Granular Cell Tumor / therapy

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  • (PMID = 19048707.001).
  • [ISSN] 1784-3286
  • [Journal-full-title] Acta clinica Belgica
  • [ISO-abbreviation] Acta Clin Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 13
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45. Elakkumanan LB, Chhabra A, Bose S, Sharma K: Granular cell myoblastoma of tongue: a rare cause of unanticipated difficult intubation. Middle East J Anaesthesiol; 2010 Feb;20(4):573-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell myoblastoma of tongue: a rare cause of unanticipated difficult intubation.
  • We report a case of granular cell myoblastoma of the tongue, as a cause of an unanticipated impossible intubation.
  • [MeSH-major] Granular Cell Tumor / pathology. Intubation, Intratracheal / methods. Neoplasms, Muscle Tissue / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20394257.001).
  • [ISSN] 0544-0440
  • [Journal-full-title] Middle East journal of anaesthesiology
  • [ISO-abbreviation] Middle East J Anaesthesiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lebanon
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46. Novakov-Mikić A, Ivanović L, Lucić M, Kiralj A, Koprivsek K, Vucković N: [Prenatal diagnosis of granular cell myoblastoma--a case report]. Med Pregl; 2006 Nov-Dec;59(11-12):573-6
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  • [Title] [Prenatal diagnosis of granular cell myoblastoma--a case report].
  • INTRODUCTION: The aim of this paper is to present a case of prenatal diagnosis of a congenital tumor of the oral cavity diagnosed at 28 weeks of gestation.
  • CASE REPORT: After the diagnosis of oral cavity tumor was made by 21) ultrasound, a 3D scan was performed, which confirmed the diagnosis revealing a peduncle at the upper border of maxilla.
  • Magnetic resonance imaging was performed, confirming the diagnosis and the site of the tumor.
  • Regular three-week follow-up scans were performed to follow the growth of the tumor, as well as the state of the amniotic fluid.
  • No tumor growth was detected, and the amniotic fluid volume was normal until 39 weeks of gestation.
  • Cesarean section was scheduled, due to the risk of tumor disruption during a vaginal delivery.
  • The histopathological diagnosis was: granular cell myoblastoma.
  • The female newborn was developing normally, and at 5 months of age there were no traces of scarring at the place of the tumor.
  • [MeSH-major] Granular Cell Tumor / congenital. Mouth Neoplasms / congenital. Mouth Neoplasms / diagnosis

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  • (PMID = 17633900.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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47. Diel P, Baadners D, Schlüpmann K, Velders M, Schwarz JP: C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression. J Mol Endocrinol; 2008 May;40(5):231-41
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  • [Title] C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression.
  • The control of satellite cell activity is a key mechanism during this process.
  • In this study, we analyzed the ability of dihydrotestosterone (DHT) and anabolic steroids to induce and modulate the differentiation of C2C12 myoblastoma cells toward myotubes.
  • The time-dependent effects on differentiation were measured and correlated with the expression of genes involved in the regulation of satellite cell activity.
  • The distribution of C2C12 cells within the cell cycle was measured by flow cytometry and differentiation by creatine kinase (CK) activity.
  • The treatment with DHT and anabolic steroids resulted in a stimulation of C2C12 cell proliferation and CK activity.
  • Our results demonstrate that the key mechanisms of satellite cell differentiation are modulated by androgens.
  • [MeSH-major] Androgens / physiology. Cell Differentiation / physiology. Cell Proliferation. Neoplasms, Muscle Tissue / metabolism. Neoplasms, Muscle Tissue / pathology. PAX7 Transcription Factor / genetics. Transforming Growth Factor beta / genetics
  • [MeSH-minor] Animals. Cell Line, Tumor. Mice. Muscle Fibers, Skeletal / pathology. Myostatin. Satellite Cells, Skeletal Muscle / pathology

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  • [ErratumIn] J Mol Endocrinol. 2014 Aug;53(1):X1
  • (PMID = 18434429.001).
  • [ISSN] 1479-6813
  • [Journal-full-title] Journal of molecular endocrinology
  • [ISO-abbreviation] J. Mol. Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Androgens; 0 / Mstn protein, mouse; 0 / Myostatin; 0 / PAX7 Transcription Factor; 0 / Pax7 protein, mouse; 0 / Transforming Growth Factor beta
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48. Kloub O, Perry A, Tu PH, Lipper M, Lopes MB: Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases. Am J Surg Pathol; 2005 Feb;29(2):247-53
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  • [Title] Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases.
  • The recently described "spindle cell oncocytoma of the adenohypophysis" is a very rare and often misdiagnosed entity.
  • A benign biologic behavior has been suggested based on the absence of recurrences with a median follow-up of 3 years.
  • Herein, we present 2 cases of recurrent spindle cell oncocytomas.
  • Ultimately, a partial resection was performed after compression of optic pathways by the tumor, and approximately 1 year later, re-resection was carried out.
  • The primary and recurrent lesions of both cases showed similar architecture with interlacing fascicles of spindle cells that alternated with areas of epithelioid-like cells that exhibited eosinophilic, granular cytoplasm.
  • The histopathologic features of these lesions are consistent with spindle cell oncocytoma of the adenohypophysis.
  • In summary, we are reporting 2 cases of recurrent spindle cell oncocytoma of adenohypophysis with longer follow-up than previously published cases, suggesting the possibility of a more aggressive behavior than has been initially considered.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Neoplasm Recurrence, Local / pathology. Pituitary Neoplasms / pathology

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  • (PMID = 15644783.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Dhingra S, Nada R, Rayat CS, Joshi K: Unusual eosinophilic variant of chromophobe cell renal carcinoma--an ultrastructural diagnosis. Indian J Pathol Microbiol; 2005 Apr;48(2):255-7
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  • [Title] Unusual eosinophilic variant of chromophobe cell renal carcinoma--an ultrastructural diagnosis.
  • A case of eosinophilic variant of chromophobe cell renal carcinoma (EVCCRC), an uncommon variety of renal cell carcinoma, occurred in a 72 year old male.
  • EVCCRC is a potentially malignant neoplasm whereas renal oncocytoma is totally benign.
  • Staining with Hale's Colloidal Iron using modified Mowry's technique showed granular cytoplasmic positivity.
  • The diagnosis was confirmed by ultrastructural examination of the tumor which revealed unique features of EVCCRC like presence of numerous cytoplasmic microvesicles along with mitochondria displaying tubulo-vesicular cristae.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / ultrastructure. Eosinophils / pathology. Kidney Neoplasms / diagnosis. Kidney Neoplasms / ultrastructure

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  • (PMID = 16758688.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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50. Liegl B, Hornick JL, Fletcher CD: Primary cutaneous PEComa: distinctive clear cell lesions of skin. Am J Surg Pathol; 2008 Apr;32(4):608-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous PEComa: distinctive clear cell lesions of skin.
  • Tumor size ranged from 0.7 to 2 cm (median size, 1.5 cm).
  • Six tumors were composed of epithelioid cells and 4 showed mixed epithelioid and spindle cell morphology.
  • Tumor cells had clear, palely eosinophilic or granular cytoplasm.
  • Multinucleate tumor giant cells were observed in 3 cases.
  • In cases where HMB-45 was positive in fewer than 5% of tumor cells (5/10), microphthalmia transcription factor was positive in the majority of the tumor cell nuclei.
  • Primary cutaneous PEComas are rare and thus far apparently benign cutaneous tumors.
  • [MeSH-major] Biomarkers, Tumor / analysis. Melanoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, Neoplasm / analysis. Calcium-Binding Proteins / analysis. Calmodulin-Binding Proteins / analysis. Dermis / pathology. Desmin / analysis. Diagnosis, Differential. Female. Giant Cells / pathology. Humans. Immunohistochemistry. Keratins / analysis. MART-1 Antigen. Male. Melanoma-Specific Antigens. Microfilament Proteins / analysis. Microphthalmia-Associated Transcription Factor / analysis. Middle Aged. Mitotic Index. Mucin-1 / analysis. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Subcutaneous Fat / pathology

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  • [CommentIn] Am J Dermatopathol. 2016 Feb;38(2):165-6 [26825164.001]
  • (PMID = 18277881.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Calmodulin-Binding Proteins; 0 / Desmin; 0 / MART-1 Antigen; 0 / MITF protein, human; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Microfilament Proteins; 0 / Microphthalmia-Associated Transcription Factor; 0 / Mucin-1; 0 / Neoplasm Proteins; 0 / calponin; 68238-35-7 / Keratins
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51. Lucendo AJ, De Rezende L, Martín-Plaza J, Larrauri J: Esophageal granular cell tumor and eosinophilic esophagitis: two interesting entities identified in the same patient. Case Rep Gastroenterol; 2008;2(1):33-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Esophageal granular cell tumor and eosinophilic esophagitis: two interesting entities identified in the same patient.
  • Endoscopy detected a submucosal tumor in the upper third of the esophagus, which was typified, via biopsy, as a granular cell tumor with benign characteristics and probably responsible for the symptoms.
  • This is the first documented case of the link between granular cell tumors and Eosinophilic esophagitis, two different disorders which could cause dysphagia in young patients.

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  • [Cites] J Allergy Clin Immunol. 1999 Aug;104(2 Pt 1):506 [10452782.001]
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  • (PMID = 21490835.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3075163
  • [Keywords] NOTNLM ; Dysphagia / Eosinophilic esophagitis / Esophagus / Granular cell tumors
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52. Huang W, Kanehira K, Drew S, Pier T: Oncocytoma can be differentiated from its renal cell carcinoma mimics by a panel of markers: an automated tissue microarray study. Appl Immunohistochem Mol Morphol; 2009 Jan;17(1):12-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncocytoma can be differentiated from its renal cell carcinoma mimics by a panel of markers: an automated tissue microarray study.
  • BACKGROUND: Differentiating oncocytoma from its renal cell carcinoma (RCC) mimics, particularly chromophobe RCC, can be difficult, especially when limited tissue is available for evaluation.
  • DESIGN: A renal cell neoplasm tissue microarray was constructed including oncocytoma (n=30), chromophobe RCC (n=18), conventional RCC (n=64), papillary RCC (n=50), and benign renal tissues (n=31).
  • CK7, CD10, epithelial membrane antigen, renal cell carcinoma marker (RCCma), vimentin, and endogenous avidin-binding activity (EABA) were studied.
  • RESULT: EABA was positive in 97% of oncocytoma, 26% of conventional RCC and 35% of papillary RCC with granular/eosinophilic (G/E) features and 6% of chromophobe RCC.

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  • (PMID = 18769342.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Vimentin; EC 2.7.11.22 / MOK protein, human; EC 2.7.11.24 / Mitogen-Activated Protein Kinases
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53. Harikumar R, Simikumar, Aravindan SK, Thomas V: Abrikosoff's tumor of the esophagus: case report and review of literature. Trop Gastroenterol; 2006 Jan-Mar;27(1):52-3
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  • [Title] Abrikosoff's tumor of the esophagus: case report and review of literature.
  • Abrikosoff's tumor or granular cell tumor is a neoplasm of neural origin, usually located in the head and neck region.
  • A majority of these neoplasms are benign.
  • Only 4-6% of granular cell tumors are located in the gastrointestinal tract.
  • [MeSH-major] Esophageal Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 16910065.001).
  • [ISSN] 0250-636X
  • [Journal-full-title] Tropical gastroenterology : official journal of the Digestive Diseases Foundation
  • [ISO-abbreviation] Trop Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 13
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54. Wiel J, Luis W, Kempf HG: [The interesting case -- case no. 70]. Laryngorhinootologie; 2005 Mar;84(3):196-9
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  • We will report two cases of newborn girls, who could not be breast fed because of a benign tumour in their oral cavity.
  • The size of neoplasm was in one case 3 x 2 cm, in the other one 2 x 1.5 cm.
  • Histological findings showed large tumour cells with abundant granular eosinophilic cytoplasm and a prominent vascularity.
  • All these findings are characteristic of congenital granular cell tumour and its synonym congenital epulis.
  • It differs from adult granular cell tumours by its prominent vascularity, the presence of scattered remnants of odontogenic epithelium, and the strong phosphatase activity.
  • [MeSH-major] Gingival Neoplasms / congenital. Granular Cell Tumor / congenital. Mouth Neoplasms / congenital

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  • (PMID = 15770569.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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55. Garrido E, Marín E, González C, Juzgado D, Boixeda D, Vázquez-Sequeiros E: [Endoscopic mucosal resection of Abrikosoff's tumor of the esophagus]. Gastroenterol Hepatol; 2008 Nov;31(9):572-5
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  • [Title] [Endoscopic mucosal resection of Abrikosoff's tumor of the esophagus].
  • [Transliterated title] Mucosectomía endoscópica de un tumor de Abrikosoff esofágico.
  • Abrikosoff's tumor (AT), or granular cell tumor (GCT), is relatively rare in the gastrointestinal tract, where the most common site is the esophagus.
  • This tumor is usually found incidentally when an upper gastrointestinal endoscopy is carried out for another reason.
  • The origin of GCT is neurogenic and the tumor is composed of eosinophilic granular cytoplasm and PAS-positive cells, which show the S-100 protein on immunohistochemistry.
  • Although GCT is usually clinically and histologically benign, some malignant cases have been reported.
  • Consensus is lacking on the treatment and follow-up of this tumor.
  • [MeSH-major] Esophageal Neoplasms / surgery. Esophagoscopy. Granular Cell Tumor / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Male. Middle Aged. Neoplasm Proteins / analysis. S100 Proteins / analysis

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  • (PMID = 19091245.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / S100 Proteins
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56. Matyja E, Maksymowicz M, Grajkowska W, Olszewski W, Zieliński G, Bonicki W: Spindle cell oncocytoma of the adenohypophysis - a clinicopathological and ultrastructural study of two cases. Folia Neuropathol; 2010;48(3):175-84
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  • [Title] Spindle cell oncocytoma of the adenohypophysis - a clinicopathological and ultrastructural study of two cases.
  • Spindle cell oncocytoma (SCO) of the pituitary gland is a relatively recently established, very rare subtype of adenohypophysis tumours that was introduced as a distinct clinicopathological entity in the fourth edition of WHO classification of the central nervous system tumours (2007).
  • It is non-endocrine neoplasm of the anterior pituitary that occurs in adults and usually follows a benign clinical course, corresponding to WHO grade I.
  • They were composed of interwoven fascicles of spindle cells exhibiting abundant eosinophilic cytoplasm of oncocytic or granular appearance.
  • Spindle cell oncocytoma of the anterior pituitary is often misdiagnosed entity of uncertain histogenesis.

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  • (PMID = 20925001.001).
  • [ISSN] 1509-572X
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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57. Walsh SN, Sangüeza OP: PEComas: a review with emphasis on cutaneous lesions. Semin Diagn Pathol; 2009 Aug;26(3):123-30
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  • The connection between angiomyolipoma (AML) of the kidney, clear cell sugar tumor (CCST) of the lung, and pulmonary lymphangioleiomyoma (LAM), was progressively discovered because of the histologic and immunophenotypic similarities between the three tumors and their frequent association with tuberous sclerosis complex (TSC).
  • Morphologically, analogous lesions found in other locations are composed of the unifying cell, the perivascular epithelioid cell (PEC).
  • These neoplasms are composed of nests and fascicles of clear to granular epithelioid and/or spindled cells with a consistent arrangement around blood vessels.
  • Most reported cutaneous PEComas follow a benign course, however, a malignant case has been reported.
  • [MeSH-major] Desmin / metabolism. Epithelioid Cells / pathology. Perivascular Epithelioid Cell Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / metabolism. Antigens, Neoplasm / metabolism. Biomarkers, Tumor / metabolism. Female. Humans. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism

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  • [CommentIn] Am J Dermatopathol. 2016 Feb;38(2):165-6 [26825164.001]
  • (PMID = 20043511.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
  • [Number-of-references] 65
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58. Yen TH, Chen Y, Fu JF, Weng CH, Tian YC, Hung CC, Lin JL, Yang CW: Proliferation of myofibroblasts in the stroma of renal oncocytoma. Cell Prolif; 2010 Jun;43(3):287-96
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  • OBJECTIVES: Myofibroblasts are a vital component of stroma of many malignant neoplasms, but it is not yet established whether stromal myofibroblasts also exist in benign tumours such as oncocytoma of the kidney.
  • RESULTS: Renal oncocytomas were composed of oncocytes, large cells with granular eosinophilic cytoplasm, arranged mostly in sheets, in tubulocystic or combined pattern.
  • Wnt/beta-catenin signalling was not implicated in this neoplasm, as there was no loss of E-cadherin membranous localization or expression of intranuclear beta-catenin in the cells.
  • CONCLUSIONS: Renal oncocytomas were composed of two independent compartments: benign oncocytes and pronounced fibrotic stroma, which consisted of proliferating myofibroblasts (SMA- and MIB-1-positive) which were associated with excessive deposition of extracellular matrix (periodic acid Schiff-component, collagen I-, collagen III- and fibronectin-positive, and desmin- and human caldesmon-negative).
  • [MeSH-minor] Aged. Biomarkers, Tumor / metabolism. Cell Proliferation. Extracellular Matrix / metabolism. Extracellular Matrix / pathology. Extracellular Matrix Proteins / metabolism. Female. Humans. Male. Middle Aged. Myoblasts / metabolism. Myoblasts / pathology. Neoplasm Invasiveness / pathology. Neoplasm Invasiveness / physiopathology. Stromal Cells / metabolism. Stromal Cells / pathology

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  • (PMID = 20412129.001).
  • [ISSN] 1365-2184
  • [Journal-full-title] Cell proliferation
  • [ISO-abbreviation] Cell Prolif.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Extracellular Matrix Proteins
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59. Pino Rivero V, Marcos García M, Rejas Ugena E, Trinidad Ruiz G, Pardo Romero G, González Palomino A, Gómez de Tejada Romero R, Blasco Huelva A: [Granular cell tumor of the tongue (Abrikossoff's tumor). Report of a case and review of the literature]. An Otorrinolaringol Ibero Am; 2005;32(1):65-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Granular cell tumor of the tongue (Abrikossoff's tumor). Report of a case and review of the literature].
  • [Transliterated title] Tumor de células granulares lingual (tumor de Abrikossoff). Presentación de un caso y revisión de la literatura.
  • Granular cell tumor, myoblastoma or Abrikossoff's tumor is an uncommon benign lesion, usually of slow-growing, that shows a predilection for the oral cavity, especially the tongue.
  • Its real etiopathogenia remains still controversial and in it's histogenesis have been implicated several cell types.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 15803921.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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60. Mentzel T, Schärer L, Kazakov DV, Michal M: Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight cases. Am J Dermatopathol; 2007 Oct;29(5):443-8
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  • Dermatofibrosarcoma protuberans (DFSP) represents a locally aggressive mesenchymal neoplasm of skin and subcutis with characteristic clinicopathologic, immunohistochemical, and molecular findings.
  • In addition to typical cases, morphologic variants such as pigmented, fibrosarcomatous, myofibroblastic, and granular cell DFSP have been described.
  • Tumor size ranged from 1.5 to 12 cm.
  • Histologically, a nodular growth with peripheral diffuse infiltration, as well as a diffusely infiltrating growth of relatively uniform spindled and stellated tumor cells containing slightly enlarged nuclei, was noted.
  • Three cases were entirely myxoid, and in five cases more than 80% of the tumor area showed myxoid stromal changes.
  • In two cases each, focal fibrosarcomatous and focal giant cell fibroblastoma-like changes were present.
  • Scattered enlarged tumor cells were seen in two cases.
  • Immunohistochemically, tumor cells in all cases stained positively for CD34, and in one case each a focal expression of alpha-smooth muscle actin and epithelial membrane antigen (EMA) was noted.
  • In conclusion, myxoid DFSP represents a very rare morphologic variant with characteristic changes that has to be distinguished from benign and malignant myxoid mesenchymal neoplasms as superficial angiomyxoma, superficial acral fibromyxoma, myxoid solitary fibrous tumor, myxoid perineurioma, low-grade myxofibrosarcoma, low-grade fibromyxoid sarcoma, myxoid liposarcoma, and myxoid synovial sarcoma.
  • [MeSH-minor] Actins / metabolism. Adult. Aged. Antigens, CD34 / metabolism. Cell Proliferation. Collagen Type I / genetics. Collagen Type I / metabolism. Diagnosis, Differential. Female. Gene Fusion / genetics. Humans. Male. Middle Aged. Mucin-1 / metabolism. Proto-Oncogene Proteins c-sis / genetics. Proto-Oncogene Proteins c-sis / metabolism. Translocation, Genetic

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  • (PMID = 17890911.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Collagen Type I; 0 / Mucin-1; 0 / Proto-Oncogene Proteins c-sis; 0 / collagen type I, alpha 1 chain
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61. Jin B, Saleh H: Pitfalls in the diagnosis of adult rhabdomyoma by fine needle aspiration: report of a case and a brief literature review. Diagn Cytopathol; 2009 Jul;37(7):483-6

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  • Adult rhabdomyoma is a rare benign tumor of striate muscle tissue usually located in the head and neck region.
  • Cytomorphologically, the tumor cells have eosinophilic finely granular cytoplasm, which sometimes can mimic other tumors.
  • We report a case of adult rhabdomyoma, which was initially misinterpreted as granular cell tumor on FNA biopsy due to lacking of typical cytological features of adult rhabdomyoma.
  • We recommend that adult rhabdomyoma should be included in differential diagnoses when the cytological features are suggestive of granular cell tumor.
  • [MeSH-major] Muscle Proteins / metabolism. Neoplasm Proteins / metabolism. Rhabdomyoma / metabolism. Rhabdomyoma / pathology

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  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19217050.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Muscle Proteins; 0 / Neoplasm Proteins
  • [Number-of-references] 13
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62. Fang HY, Wu CY, Huang HJ, Lin YM: Granular cell tumor of the lung. Lung; 2010 Aug;188(4):355-7
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  • [Title] Granular cell tumor of the lung.
  • A thoracoscopic RML lobectomy was then performed and immunohistochemical study and Ki-67 proliferative index on the pathology sample demonstrated a benign granular cell tumor.
  • Thirty-six months after surgery, the patient remains symptom-free and there has been no recurrence of the tumor on follow-up CT scan.
  • [MeSH-major] Granular Cell Tumor / radionuclide imaging. Lung Neoplasms / radionuclide imaging

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  • (PMID = 20066540.001).
  • [ISSN] 1432-1750
  • [Journal-full-title] Lung
  • [ISO-abbreviation] Lung
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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63. Hes O, Michal M, Síma R, Vanecek T, Brunelli M, Martignoni G, Kuroda N, Alvarado Cabrero I, Perez-Montiel D, Hora M, Urge T, Dvorák M, Jarosová M, Yang X: Renal oncocytoma with and without intravascular extension into the branches of renal vein have the same morphological, immunohistochemical, and genetic features. Virchows Arch; 2008 Feb;452(2):193-200
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  • Tumor cells were positive for cytokeratins, mitochondrial-antigen (MIA), epithelial membrane antigen (EMA), and parvalbumin; five of seven tumors were focally positive for CD117.
  • (3) the absence of metastases suggests an overall benign behavior of this tumor, but this has to be substantiated by further studies with a long-term follow-up; and (4) in a renal tumor with granular cytoplasm showing renal vein extension, it is necessary to carefully exclude renal cell carcinomas such as chromophobe RCC, oncocytic variant of papillary RCC, and granular variant of clear cell RCC.
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Chromosome Aberrations. Cytoplasm / ultrastructure. DNA, Neoplasm / analysis. Female. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Mitochondria / ultrastructure. Neoplasm Invasiveness. Nephrectomy

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  • (PMID = 18066590.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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64. Gajda M, Welzel C, Holzhausen HJ, Jamali Y, Schrom T, Hauptmann S, Bloching M: [Multifocal adult rhabdomyoma of the neck: a rare entity]. Otolaryngol Pol; 2005;59(6):883-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A review of the world literature revealed about 19 acceptable cases of benign, multifocal adult-type rhabdomyoma with a distinct male predominance.
  • The pathogenesis of this benign striated muscle tumor is still unclear.
  • The differential diagnoses of rhabdomyoma in adults are myoblastoma or Abrikossof tumor, reticulohistiocytoma, rhabdomyosarcoma and hibernoma.
  • Although adult rhabdomyomas have a distinct histology, they often are mistaken for a variety of other lesions, particularly Abrikossof tumor.
  • Light microscopy showed large round to elongated cells with granular, highly eosinophilic cytoplasm, often with peripheral vacuolation.
  • Electron microscopic studies confirmed the tumor's myogenic origin.

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  • (PMID = 16521457.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 16
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65. Collins BT, Phillips NJ, Hsueh EC: Fine needle aspiration biopsy of splenic hamartoma with bizarre stromal cells: a case report. Acta Cytol; 2008 May-Jun;52(3):347-50
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  • BACKGROUND: Splenic hamartoma is a rare benign "tumor" with disorganized red pulp tissue without white pulp elements.
  • Cell fragments possessed a variable proportion of spindle to ovoid cells.
  • The bizarre large cells had single or multiple round, oval or distorted nuclei with granular chromatin.
  • Cell block mirrored the smear pattern, and the bizarre large cells were negative by immunohistochemistry.
  • Malignant spindle cell neoplasm was favored.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Female. Humans. Middle Aged. Vimentin / metabolism

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  • (PMID = 18540303.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
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66. Takei H, Goodman JC, Tanaka S, Bhattacharjee MB, Bahrami A, Powell SZ: Pituicytoma incidentally found at autopsy. Pathol Int; 2005 Nov;55(11):745-9
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  • Pituicytoma is a rare benign neoplasm, occurring in the sellar and suprasellar regions.
  • The tumor was composed primarily of bipolar, occasionally unipolar, cells with syncytial fibrillary cytoplasm, arranged in short curvilinear fascicles and/or storiform patterns.
  • Unusual histological features were seen, which included a few groups of large pleomorphic tumor cells with abundant, glassy, eosinophilic cytoplasm, occasionally associated with multinucleated giant tumor cells, and scattered Herring bodies within the tumor.
  • Immunohistochemically, the tumor showed diffuse strong expression of glial fibrillary acidic protein, S-100 protein, and vimentin.
  • Epithelial membrane antigen immunoreactivity was focally observed, mainly in the large tumor cells.
  • Distinction from other intrasellar tumors (granular cell tumor and pilocytic astrocytoma) is important.

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  • (PMID = 16271088.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Glial Fibrillary Acidic Protein; 0 / Mucin-1; 0 / S100 Proteins; 0 / Vimentin
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67. Jakobiec FA, Colby K, Bajart AM, Saragas SJ, Moulin A: Immunohistochemical studies of atypical conjunctival melanocytic nevi. Arch Ophthalmol; 2009 Aug;127(8):970-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Routine histochemical staining was performed with multiparametric immunohistochemical analysis with monoclonal antibodies immunoreacted on paraffin sections to identify the following cell antigens: S-100, MART-1, HMB-45, CD45, CD68, CD1a, lysozyme, and Ki-67 (nuclear proliferation protein).
  • RESULTS: A unique granular cell nevus contained periodic acid-Schiff-positive, diastase-resistant granules and immunoreacted with monoclonal antibodies against S-100 protein and melanocytic-associated antigens MART-1 and HMB-45.
  • Results for CD45, CD1a, CD68, and lysozyme immunostaining of the granular cells were negative.
  • Two epithelioid cell (clonal or inverted) nevi exhibited an identical immunohistochemical profile.
  • Only the balloon cell nevus was MART-1-positive and HMB-45-negative.
  • The granular cell and blue nevi immunoreacted negligibly with Ki-67 (approximately 1% of cells).
  • HMB-45 immunoreactivity of the granular, epithelioid/clonal, and blue nevi did not indicate a more active or proliferative lesion but instead suggested abnormal melanogenesis.
  • Ki-67 was the most valuable immunohistochemical adjunct to morphology for the diagnosis of these benign variant conjunctival nevi, because melanomas display a much higher proliferation index (>10% nuclear positivity among all cells counted) than the current nevi (approximately 1%).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Conjunctival Neoplasms / metabolism. Neoplasm Proteins / metabolism. Nevus, Blue / metabolism. Nevus, Pigmented / metabolism
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Antigens, Neoplasm / metabolism. Female. Humans. Immunoenzyme Techniques. Ki-67 Antigen / metabolism. MART-1 Antigen. Male. Melanoma-Specific Antigens. Middle Aged. Muramidase / metabolism. Retrospective Studies. S100 Proteins / metabolism. Young Adult

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  • (PMID = 19667333.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 3.2.1.17 / Muramidase
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68. Joung MK, Lee YJ, Chung CU, Lee JE, Jung SS, Kim SY, Kim JO: A case of granular cell tumor of the trachea. Korean J Intern Med; 2007 Jun;22(2):101-5
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  • [Title] A case of granular cell tumor of the trachea.
  • The pathologic findings showed a benign granular cell tumor.
  • The respiratory symptoms resolved after biopsying the tumor.
  • On follow up, there were no signs of recurrence of the granular cell tumor after a period of 24 months.
  • [MeSH-major] Chest Pain / diagnosis. Granular Cell Tumor / diagnosis. Hemoptysis. Tracheal Neoplasms / diagnosis

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  • (PMID = 17616025.001).
  • [ISSN] 1226-3303
  • [Journal-full-title] The Korean journal of internal medicine
  • [ISO-abbreviation] Korean J. Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2687619
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69. Miron I, Miron L, Dumitraş S, Aprodu G, Ciobanu A, Tansanu I: [Statistical study of the evolution over ten years of the clinical and therapeutic approach in childhood soft tissue sarcoma]. Rev Med Chir Soc Med Nat Iasi; 2007 Apr-Jun;111(2):358-62
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

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  • Based on histological examination 19 cases (32.75%) were of rhabdomyosarcoma type with following subtypes: alveolar--7 patients, embryonic-- 9 cases, fusiform - 2 cases, bothrioid--1 case), 8 cases were undifferentiated soft tissue sarcomas and one patient had a tumor of pleiomorphic type; 13 children (22.41%) had non-rhabdomyosarcoma soft tissue sarcomas: 6 fibrosarcomas, 2 synovial sarcomas, 1 leiomyosarcoma, 1 Kaposi sarcoma, 1 case of malignant peripheral nerve sheath tumor, 1 case of angioma tumor, one liposarcoma; 16 cases were included in soft tissue tumors of uncertain origin (fibromatosis--6 cases, fibrous histiocytoma--4 cases, hamartoma--cases, myoblastoma--1 case, fibro-xanthoma--1 case, hemangioendothelioma--1 case); 1 PPNET (Askin tumor).

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  • (PMID = 17983168.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
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70. Wang Y, Li X, Guo Y, Chan L, Guan X: alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice. Metabolism; 2010 Jul;59(7):967-76
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  • In addition, metabolic action and cellular signaling of LA were studied in cultured mouse myoblastoma C2C12 cells.

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  • (PMID = 20015518.001).
  • [ISSN] 1532-8600
  • [Journal-full-title] Metabolism: clinical and experimental
  • [ISO-abbreviation] Metab. Clin. Exp.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / K01 DK075489-04; United States / NIDDK NIH HHS / DK / R03 DK084125; United States / NHLBI NIH HHS / HL / R01 HL051586; United States / NHLBI NIH HHS / HL / HL51586; United States / NIDDK NIH HHS / DK / DK075489-04S1; United States / NHLBI NIH HHS / HL / R01 HL051586-12; United States / NIDDK NIH HHS / DK / K01 DK075489-01; United States / NHLBI NIH HHS / HL / HL051586-12; United States / NIDDK NIH HHS / DK / R03 DK084125-02; United States / NIDDK NIH HHS / DK / DK075489-04; United States / NIDDK NIH HHS / DK / DK075489-01; United States / NIDDK NIH HHS / DK / K01 DK075489-04S1; United States / NIDDK NIH HHS / DK / 5K01DK75489; United States / NIDDK NIH HHS / DK / K01 DK075489; United States / NIDDK NIH HHS / DK / DK084125-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Fatty Acids; 0 / Ppargc1a protein, mouse; 0 / Trans-Activators; 0 / Transcription Factors; 47E5O17Y3R / Phenylalanine; 63231-63-0 / RNA; 73Y7P0K73Y / Thioctic Acid; 9G2MP84A8W / Deoxyglucose; EC 2.7.11.11 / Cyclic AMP-Dependent Protein Kinases
  • [Other-IDs] NLM/ NIHMS166156; NLM/ PMC2882509
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71. Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG: A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg; 2005 Feb;102(2):256-66
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  • OBJECT: This is a retrospective review of 146 surgically treated benign and malignant peripheral non-neural sheath tumors (PNNSTs).
  • Tumor classifications with patient numbers, locations of benign PNNSTs, and surgical techniques and adjunctive treatments are presented.
  • The results of a literature review regarding tumor frequencies are presented.
  • METHODS: One hundred forty-six patients with 111 benign and 35 malignant PNNSTs were treated between 1969 and 1999 at the Louisiana State University Health Sciences Center (LSUHSC).
  • The benign tumors included 33 ganglion cysts, 16 cases of localized hypertrophic neuropathy, 12 lipomas, 12 tumors of vascular origin, and 11 desmoid tumors.
  • There were four each of lipofibrohamartomas, myositis ossificans, osteochondromas, and ganglioneuromas; two each of meningiomas, cystic hygromas, myoblastoma or granular cell tumors, triton tumors, and lymphangiomas; and one epidermoid cyst.
  • The locations of benign PNNSTs were the following: 33 in the brachial plexus region, 39 in an upper extremity, one in the pelvic plexus, and 38 in a lower extremity.
  • There were two melanomas metastatic to nerve and one tumor each that had metastasized from the bladder, rectum, skin, head and neck, and thyroid, and from a primary Ewing sarcoma.
  • CONCLUSIONS: There were more benign PNNSTs than malignant ones.
  • Benign tumors were relatively equally distributed in the brachial plexus region and upper and lower extremities, with the exception of the pelvic plexus, which had only one tumor.

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  • (PMID = 15739553.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Stieglitz F, Kitz R, Schäfers HJ, Eickmeier O, Rose M, Fellbaum C, Zielen S: Granular cell tumor of the trachea in a child. Ann Thorac Surg; 2005 Feb;79(2):e15-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of the trachea in a child.
  • Granular cell tumors are uncommon benign neoplasms.
  • We present the case of a 14-year-old girl with a granular cell tumor of the trachea.
  • The tumor was incidentally found at bronchoscopy performed to exclude suspected foreign body aspiration.
  • Biopsies revealed the histologic pattern of a benign granular cell tumor.
  • She has not had any recurrence of the tumor during 3 years of follow-up.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Granular Cell Tumor / surgery. Tracheal Neoplasms / diagnosis. Tracheal Neoplasms / surgery

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  • (PMID = 15680798.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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73. Alrahwan D, Staerkel G, Gong Y: Fine needle aspiration cytology of a metastatic duct carcinoma of the prostate: a case report. Acta Cytol; 2006 Jul-Aug;50(4):469-72
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  • Without proper clinical information, a fine needle aspiration (FNA) diagnosis of metastatic PDC can be challenging as this tumor can morphologically mimic adenocarcinomas from other sites.
  • He had undergone a prostatectomy 30 years earlier for "benign prostatic hypertrophy" but had no known history of malignancy.
  • The aspirates were hypercellular and composed of numerous monolayered or folded cohesive sheets of tumor cells with minimal cytologic atypia.
  • The tumor cells had abundant, clear cytoplasm, evenly spaced nuclei, finely granular chromatin, inconspicuous nucleoli and occasional mitotic figures.
  • Cell block sections revealed tumor cells forming tubulopapillary architecture lined with tall columnar cells with focal nuclear pseudostratification, reminiscent of uterine endometrial carcinoma.
  • Positive immunoreactivity for prostate-specific antigen and prostatic acid phosphatase confirmed the tumor's prostatic origin.
  • CONCLUSION: Because of the rarity and nonspecific cytomorphologic characteristics of this tumor, clinical history, radiologic findings and a high index of suspicion in conjunction with ancillary studies are important in achieving a correct FNA diagnosis of metastatic PDC.
  • [MeSH-minor] Aged, 80 and over. Biopsy, Fine-Needle. Humans. Male. Neoplasm Metastasis. Pelvic Bones / pathology

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  • (PMID = 16901017.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Sugiyama T, Nakagawa T, Narita M, Nakamura S, Inui M, Tagawa T: Pedunculated oncocytic carcinoma in buccal mucosa: immunohistochemical and ultrastructural studies. Oral Dis; 2006 May;12(3):324-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An incision biopsy revealed the diagnosis of oncocytic tumor, and enucleation was performed.
  • The tumor was stained for immunohistochemical analysis using the ABC method and antibodies against cytokeratin (CK), epithelial membrane antigen (EMA), desmin, S-100 protein and muscle-specific actin, respectively.
  • The tumor was stained with uranyl acetate and lead citrate for visualization by electron microscopy.
  • RESULTS: Histopathology results revealed that the tumor consisted of oncocytic cells, characterized by eosinophilic and granular cytoplasm, and atypical nuclei.
  • Electron microscopy revealed numerous dilated cytoplasmic mitochondria, and the cell contours and nucleic shapes of tumor cells were often irregular.
  • CONCLUSIONS: Because the histopathologic features of OC are similar to those of benign oncocytoma, the diagnosis of OC must be confirmed by a combination of clinical and ultrastructural characteristics.
  • [MeSH-minor] Aged, 80 and over. Cheek / pathology. Humans. Immunohistochemistry. Keratins / analysis. Male. Microscopy, Electron, Transmission. Mitochondria / pathology. Mouth Mucosa / pathology. Mucin-1 / analysis. Neoplasm Invasiveness

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  • (PMID = 16700744.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Mucin-1; 68238-35-7 / Keratins
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75. Lu D, Vohra P, Chu PG, Woda B, Rock KL, Jiang Z: An oncofetal protein IMP3: a new molecular marker for the detection of esophageal adenocarcinoma and high-grade dysplasia. Am J Surg Pathol; 2009 Apr;33(4):521-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • IMP3 is an oncofetal protein and has been demonstrated to be associated with aggressive tumor behavior.
  • IMP3 showed strong cytoplasmic granular staining in 138 of 147 (94%) of invasive esophageal adenocarcinomas, 13 of 14 (93%) of metastatic esophageal adenocarcinomas, and 49 of 52 (94%) of high-grade dysplasias.
  • Expression of IMP3 was not found in adjacent benign squamous and glandular mucosa.
  • [MeSH-major] Adenocarcinoma / diagnosis. Barrett Esophagus / diagnosis. Biomarkers, Tumor / metabolism. Esophageal Neoplasms / diagnosis. Neoplasm Proteins / metabolism. Precancerous Conditions / diagnosis. RNA-Binding Proteins / metabolism
  • [MeSH-minor] Cell Transformation, Neoplastic. Esophagus / metabolism. Esophagus / pathology. Esophagus / surgery. Fluorescent Antibody Technique, Direct. Humans. Immunoenzyme Techniques. Mucous Membrane / metabolism. Mucous Membrane / pathology

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  • (PMID = 19047899.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / IMP3 protein, human; 0 / Neoplasm Proteins; 0 / RNA-Binding Proteins
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76. Huang P, Staerkel G, Sneige N, Gong Y: Fine-needle aspiration of pancreatic serous cystadenoma: cytologic features and diagnostic pitfalls. Cancer; 2006 Aug 25;108(4):239-49
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The preoperative diagnosis of pancreatic serous cystadenoma (SCA) is important because as a typically benign tumor it can be treated expectantly, whereas many other cystic tumors require excision.
  • This study examines the cytology, clinical and radiologic features, diagnostic accuracy of fine-needle aspiration (FNA), and potential pitfalls associated with this rare tumor.
  • Aspirates were sparsely cellular against a clean or granular, proteinaceous background.
  • Tumor cells formed loose clusters or monolayered sheets composed of cuboidal cells with indistinct cell borders and granular or clear cytoplasm that was often stripped from the nucleus.
  • Seven (25%) of the aspirates were initially classified as "consistent with SCA," 6 (21%) as "no malignant cells," 3 (11%) as "nondiagnostic specimen," 3 (11%) as "suspicious for malignancy," 3 (11%) as "rare atypical cells," and 6 (21%) as "probably or consistent with mucinous cystic neoplasm."
  • Contaminating GI epithelium and mucin should be distinguished from components of a mucinous neoplasm.

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16691573.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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77. Zhou CX, Gao Y: Oncocytoma of the salivary glands: a clinicopathologic and immunohistochemical study. Oral Oncol; 2009 Dec;45(12):e232-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present a clinicopathologic and immunohistochemical study of 21 Chinese patients with oncocytoma of salivary gland origin, a rare benign tumour composed exclusively of large epithelial cells with eosinophilic granular cytoplasm (oncocytes).
  • Typical oncocytes were observed in all cases, with one clear cell variant found.
  • In summary, clinical diagnosis for an oncocytoma is challenging for its similar features to other benign tumours.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. China. Diagnosis, Differential. Female. Humans. Male. Microscopy, Electron. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 19796983.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / MIB-1 antibody; 0 / Neoplasm Proteins
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78. Petersson F, Kutzner H, Spagnolo DV, Bisceglia M, Kacerovska D, Vazmitel M, Michal M, Kazakov DV: Adenoid cystic carcinoma-like pattern in spiradenoma and spiradenocylindroma: a rare feature in sporadic neoplasms and those associated with Brooke-Spiegler syndrome. Am J Dermatopathol; 2009 Oct;31(7):642-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Spiradenoma is a benign, morphologically well-defined cutaneous adnexal neoplasm that is closely related to cylindroma.
  • The ACC-like areas were typified by cribriform formations of epithelial cells concentrically arranged around gland-like spaces filled with mucin, homogeneous eosinophilic material, or granular basophilic material.
  • Although well-developed bilayered glands with a demonstrable peripheral myoepithelial cell layer were not recognizable in the ACC-like areas, immunohistochemistry demonstrated myoepithelial differentiation in these portions of the tumors.
  • When present in the ACC-like areas, ductal structures manifested a rather squamoid lining, without a recognizable peripheral myoepithelial cell layer.

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  • (PMID = 19633533.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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79. Quatresooz P, Piérard GE: Distinct expression patterns of alpha1 (IV) and alpha5 (IV) collagen chains in cylindroma and malignant cylindroma. Int J Mol Med; 2005 Jan;15(1):27-31
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  • Alterations in the expression of these alpha chains have been described in some other conditions including basal cell carcinomas, testes with spermatogenic dysfunction and colorectal carcinomas.
  • In all cylindromas, a thin continuous and sharply limited immunolabelling for the alpha1 (IV) collagen chain was abutted to the tumoral cell aggregates.
  • Globular structures encased in the cell aggregates also exhibited a thin peripheral rim positive for the alpha1 (IV) collagen chain.
  • The immunoreactivity was faint and granular in the center of the globules.
  • The malignant cylindroma showed a linear immunoreactivity for the alpha1 (IV) collagen chain undistinguishable from the pattern seen in the benign cylindromas.
  • No immunoreactivity was present for the alpha5 (IV) collagen chain in the malignant neoplasm.
  • The distinctive patterns of expression of the alpha1 (IV) and alpha5 (IV) collagen chains may be related to the histogenic sudoral origin of cylindromas without any relationship with the benign or malignant nature of the neoplasm.

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  • (PMID = 15583824.001).
  • [ISSN] 1107-3756
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Collagen Type IV
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80. Lee J: Epithelioid cell histiocytoma with granular cells (another nonneural granular cell neoplasm). Am J Dermatopathol; 2007 Oct;29(5):475-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid cell histiocytoma with granular cells (another nonneural granular cell neoplasm).
  • [MeSH-major] Granular Cell Tumor / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17890918.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Vimentin; EC 2.3.2.13 / Factor XIIIa
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81. Behroozan DS, Goldberg LH, Glaich AS, Kaplan B, Kaye VN: Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms. Dermatol Surg; 2006 Jul;32(7):958-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms.
  • [MeSH-minor] Adult. Carcinoma / pathology. Carcinoma / surgery. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Epidermal Cyst / pathology. Epidermal Cyst / surgery. Female. Forehead / pathology. Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Heel / pathology. Humans. Male. Middle Aged. Neoplasm Metastasis. Nose / pathology. Pilomatrixoma / pathology. Pilomatrixoma / surgery. Scalp / pathology

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  • (PMID = 16875482.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Sobol SE, Samadi DS, Wetmore RF: Pediatric subglottic granular cell myoblastoma. Otolaryngol Head Neck Surg; 2005 Apr;132(4):655-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric subglottic granular cell myoblastoma.
  • [MeSH-major] Airway Obstruction / etiology. Glottis. Granular Cell Tumor / diagnosis. Laryngeal Neoplasms / diagnosis. Respiratory Sounds / etiology. Tracheal Stenosis / etiology

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  • (PMID = 15806064.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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