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1. Ruiz-Caro R, Veiga MD: In vitro Evaluation of Acyclovir/Chitosan Floating Systems. Materials (Basel); 2010 Dec 06;3(12):5195-5211

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chitosan (CS) floating lyophilized formulations (L) for gastric drug delivery of acyclovir (ACV) have been developed.
  • The results demonstrated that the freeze-drying process achieved effective floating systems capable of remaining within the stomach while the total amount of ACV is released from L.

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  • (PMID = 28883376.001).
  • [ISSN] 1996-1944
  • [Journal-full-title] Materials (Basel, Switzerland)
  • [ISO-abbreviation] Materials (Basel)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; Acyclovir / chitosan / controlled release / floating freeze-dried formulations / swelling behavior
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2. Palanivelu C, Rangarajan M, Parthasarathi R, Senthilkumar R: Laparoscopic resection for benign tumors of the stomach. JSLS; 2007 Jan-Mar;11(1):81-6
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic resection for benign tumors of the stomach.
  • BACKGROUND: Of all gastric tumors, less than 5% are benign.
  • The traditional treatment of symptomatic and some asymptomatic benign tumors has ranged from mucosal resection to limited gastrectomy.
  • Since the advent of laparoscopy, many different laparoscopic approaches to resection of benign gastric tumors have now been described in the literature.
  • METHODS: We reviewed our experience with laparoscopic approaches to surgical resection of 7 benign gastric tumors.
  • The tumor locations were the body (posterior wall), 3 cases; body (anterior wall), 1 case; lesser curvature, 1 case; fundus, 1 case, and antrum, 1 case.
  • Tumor size ranged from 2 cm to 6 cm in the greatest diameter.
  • There has been no tumor recurrence with a mean follow-up of 26 months.
  • DISCUSSION: Laparoscopic approach is slowly carving a niche for itself in the treatment of benign tumors of the stomach.
  • The basic principles are obtaining a precise preoperative pathological diagnosis; accurate tumor localization; achievement of tumor-free margins; avoidance of spillage of stomach contents, careful dissection of tumors in the esophagogastric junction, and preventing tumor seeding.
  • CONCLUSION: Based on ours and other studies, laparoscopic resection of benign gastric tumors is safe and feasible.

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  • (PMID = 17651562.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015806
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3. Yun M, Choi HS, Yoo E, Bong JK, Ryu YH, Lee JD: The role of gastric distention in differentiating recurrent tumor from physiologic uptake in the remnant stomach on 18F-FDG PET. J Nucl Med; 2005 Jun;46(6):953-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of gastric distention in differentiating recurrent tumor from physiologic uptake in the remnant stomach on 18F-FDG PET.
  • Physiologic (18)F-FDG uptake in the stomach can often cause false-positive results and lowers the usefulness of (18)F-FDG PET in evaluating the remnant stomach.
  • We assessed the role of gastric distension to see whether it is beneficial for the differentiation of recurrent tumors from physiologic (18)F-FDG uptake in the remnant stomach.
  • METHODS: Thirty patients (22 men and 8 women; age range, 27-80 y; mean age, 58.3 y) with a history of subtotal gastrectomy for gastric cancer underwent (18)F-FDG PET for various clinical indications.
  • After whole-body imaging, the patients were asked to drink water, and then spot imaging of the stomach was performed. (18)F-FDG uptake in the remnant stomach was considered positive for malignancy if it was persistently increased, whether focal or diffuse, after water ingestion.
  • We used 2 standardized uptake value (SUV) criteria to differentiate benign from malignant uptake.
  • First, a lesion was considered benign if its SUV was less than 2 on whole-body imaging.
  • Second, for a lesion with an SUV of 2 or above, it was classified as benign if SUV decreased by more than 10% after water ingestion.
  • When an SUV cutoff of 2 was applied for malignancy before water ingestion, all 17 patients with local recurrence were correctly identified, but 11 of the 13 patients without local recurrence were falsely considered to have a recurrent tumor in the remnant stomach.
  • CONCLUSION: Gastric distension by having patients drink a glass of water seems to be a simple, cost-effective way of improving the diagnostic accuracy of (18)F-FDG PET in patients with suspected recurrence in the remnant stomach.
  • Visual analysis with special attention to the configuration of (18)F-FDG activity after water ingestion seems to be more useful than the change in SUV in evaluating the remnant stomach.
  • [MeSH-major] Adenocarcinoma / diagnosis. Fluorodeoxyglucose F18. Gastric Stump / radionuclide imaging. Neoplasm Recurrence, Local / diagnosis. Radiopharmaceuticals. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. False Positive Reactions. Female. Fluorine Radioisotopes / pharmacokinetics. Gastrectomy. Humans. Male. Middle Aged. Positron-Emission Tomography. Whole-Body Counting

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
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  • (PMID = 15937305.001).
  • [ISSN] 0161-5505
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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4. Bates J: Is it me? Nurs Stand; 2007 Mar 14;21(27):28

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 'Are you going to put a tube down into my stomach?

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  • (PMID = 27958949.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. Patti R, Almasio PL, Di Vita G: Granular cell tumor of stomach: a case report and review of literature. World J Gastroenterol; 2006 Jun 7;12(21):3442-5
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumor of stomach: a case report and review of literature.
  • Granular cell tumor (GCT) was described for the first time by Abrikosoff in 1926.
  • It is a relatively rare neoplasm that may occur at many sites, but most commonly in the skin or soft tissues.
  • The occurrence of GCT in the gastrointestinal tract is rare, accounting approximately for 8% of all tumors, among which the most common site is the esophagus, whereas gastric localization is very rare.
  • Gastric GCTs can be solitary or, more frequently, associated with other gastrointestinal localization.
  • Although GCTs are usually clinically and histologically benign, some malignant cases have been reported.
  • Histologically, these tumors consist of polygonal and fusiform cells disposed in compact "nests" and immunohistochemical staining for S-100 protein supports the proposed derivation from Schwann cells.
  • A correct preoperative diagnosis of this tumor can only be made in 50% of all patients and it is always based on endoscopic biopsy.
  • In this study, the authors reported a case of a 49-year-old woman with a solitary granular cell tumor of the stomach with infiltrative pattern, successfully treated with surgical resection.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / surgery. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery

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  • (PMID = 16733867.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC4087881
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6. Brock KK, Sharpe MB, Dawson LA, Kim SM, Jaffray DA: Accuracy of finite element model-based multi-organ deformable image registration. Med Phys; 2005 Jun;32(6Part1):1647-1659

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For the abdominal cases, the liver, spleen, and external surface were explicitly deformed and the stomach and kidneys were implicitly deformed.

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  • [Copyright] © 2005 American Association of Physicists in Medicine.
  • (PMID = 28513963.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Anatomy / Bifurcations / Cancer / Clinical applications / Field emitters / Finite element methods / Finite-element and Galerkin methods / Hemodynamics / Image analysis / Image registration / Liver / Lungs / Materials properties / Mechanical and electrical properties of tissues and organs / Medical imaging / Pneumodyamics, respiration / biomechanics / biomedical MRI / finite element analysis / image registration / kidney / liver / lung / medical image processing / pneumodynamics
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7. Yao HL, Yang ZL, Li YG: [Expression and significance of prostate stem cell antigen and Oct-4 in benign and malignant lesions of the stomach]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 Jul;33(7):623-7
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression and significance of prostate stem cell antigen and Oct-4 in benign and malignant lesions of the stomach].
  • OBJECTIVE: To determine on the expression of prostate stem cell antigen (PCSA )and Oct-4 and detect their clinicopathological significance in benign and malignant lesions of the stomach.
  • METHODS: EnVision immunohistochemistry for assaying the expression of PSCA and Oct-4 was used in paraffin-embedded sections from specimens of primary foci (n = 58) and metastatic foci of regional lymph nodes (n = 36) of gastric cancer, peritumoral tissues (n = 20), and benign lesions of the stomach (n = 80).
  • RESULTS: The positive rates of PSCA and Oct-4 were significantly higher in gastric cancer than those in peritumoral tissues and benign lesions (P<0.05 or P<0.01).The positive cases of PSCA and Oct-4 in peritumoral tissues and benign lesions showed mild- to severe-atypical hyperplasia.
  • No difference of the positive rate of PSCA and Oct-4 was found between the primary foci and the metastatic foci of gastric cancer(P > 0.05).
  • The positive rates of PSCA and Oct-4 were significantly lower in infiltrating depth T(1) to approximately T(2), non-metastasis of lymph nodes, metastasis of lymph nodes N1 site, and non-metastasis of distant organs than those in infiltrating depth T(3) to approximately T(4), metastasis of lymph nodes, metastasis of lymph node N(2) to approximately N(3) site, and metastasis of distant organs(P < 0.05 or P < 0.01).Conclusion The expressive levels of PSCA and Oct-4 might be related to the invasive potential, metastasis of lymph nodes, and distant organs, it suggested the expressions levels of PSCA and Oct-4 might be important markers for reflecting the biological behaviors and prognosis of gastric cancer.
  • [MeSH-major] Biomarkers, Tumor. Membrane Glycoproteins / biosynthesis. Neoplasm Proteins / biosynthesis. Octamer Transcription Factor-3 / biosynthesis. Stomach Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Antigens, Neoplasm. Female. GPI-Linked Proteins. Humans. Male. Middle Aged. Prognosis

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  • (PMID = 18667777.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / Neoplasm Proteins; 0 / Octamer Transcription Factor-3; 0 / PSCA protein, human
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8. Kim JY, Whang JH, Zhou W, Shin J, Noh SM, Song IS, Kim JY, Lee SH, Kim J: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation. Epigenetics; 2009 Jul 01;4(5):313-321

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The opposing influences of promoter methylation of VEGFR and increased VEGF expression concurrently influence Flt-1 and KDR expression in stomach cancer, colon cancer and hepatocellular carcinoma.

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  • (PMID = 28001118.001).
  • [ISSN] 1559-2308
  • [Journal-full-title] Epigenetics
  • [ISO-abbreviation] Epigenetics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Allen D: Standard life. Nurs Stand; 2006 Aug 23;20(50):24

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : Dead bodies. Not usually a laughing matter, but I can barely suppress a titter when Silent Witness comes on the TV; every week someone with a serious expression upends the contents of a rubbery stomach into a dish and says thoughtfully: 'Hmm, last meal was a sausage. '

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  • (PMID = 27991169.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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10. Leeper A: Starting out - Battling a stomach bug gives me an idea of how patients feel. Nurs Stand; 2006 Nov 22;21(11):25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Starting out - Battling a stomach bug gives me an idea of how patients feel.

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  • (PMID = 28001882.001).
  • [ISSN] 2047-9018
  • [Journal-full-title] Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • [ISO-abbreviation] Nurs Stand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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11. Chaudry NU, Zafar S, Israr-ul-Haque: Benign nerve sheath tumor of stomach. J Coll Physicians Surg Pak; 2007 May;17(5):277-9
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign nerve sheath tumor of stomach.
  • Gastrointestinal mesenchymal tumors are a group of tumors, which originate from the mesenchymal stem cells of the gastrointestinal tract.
  • Gastric schwannoma is a very rare gastrointestinal mesenchymal tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms.
  • Endoscopic examination showed a round submucosal tumor with a central ulceration along the greater curvature of the stomach.
  • The pathological examination revealed a picture of spindle cell tumor.
  • Immunohistochemical stain was strongly positive for S-100 protein stain, and non-reactive for CD34, CD117, consistent with benign nerve sheath tumor of stomach i.e. gastric schwannoma.
  • [MeSH-major] Neurilemmoma / diagnosis. Neurilemmoma / surgery. Stomach Neoplasms / diagnosis. Stomach Neoplasms / surgery

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  • (PMID = 17553326.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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12. Angeles-Angeles A: [Endocrine neoplasm of the stomach. Study of thirteen cases]. Gac Med Mex; 2005 May-Jun;141(3):207-13
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endocrine neoplasm of the stomach. Study of thirteen cases].
  • [Transliterated title] Tumores endocrinos del estómago. Análisis de 13 casos.
  • A Thirteen patients with primary endocrine neoplasm of the stomach were studied for 20 years.
  • These two forms of neoplasm showed important differences: those associated with atrophic gastritis had hypergastrinemia, all of the multiple small tumors confined to the corpus and fundus were well differentiated carcinoids associated with intestinal metaplasia and G cell hyperplasia in antrum and ECL cell hyperplasia in corpus and fundus.
  • Tumors were clinically benign, with an excellent prognosis.
  • All patients are currently alive with no evidence of neoplasm.
  • In contrast, sporadic carcinoids were large isolated tumors originating in the antrum or corpus.
  • Two patients died as a consequence of the neoplasm; all of them were moderately differentiated and in none of the cases we found evidence of endocrine hyperplasia.
  • Al four neuroendocrine carcinomas had a clinical course similar to that of gastric adenocarcinomas and were poorly differentiated large tumors.
  • We conclude that gastric carcinoids associated with atrophic gastritis have an excellent prognosis.
  • [MeSH-major] Stomach Neoplasms / pathology

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  • (PMID = 16025986.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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13. Iwahashi M, Takifuji K, Ojima T, Nakamura M, Nakamori M, Nakatani Y, Ueda K, Ishida K, Naka T, Ono K, Yamaue H: Surgical management of small gastrointestinal stromal tumors of the stomach. World J Surg; 2006 Jan;30(1):28-35
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of small gastrointestinal stromal tumors of the stomach.
  • Small gastrointestinal stromal tumors (GISTs) (< 3 cm) occasionally are found in the stomach during endoscopy.
  • There is no consensus about the surgical management of these small tumors, although this clinical issue is crucial because some of the tumors show unexpected malignant behavior.
  • In this study, we evaluated the clinical management of patients with gastric GISTs who underwent surgical resection.
  • Altogether, 31 patients with gastric GISTs were examined retrospectively.
  • Surgical resection was fundamentally indicated for the patients with gastric GISTs suspected to be malignant by endoscopy or endoscopic ultrasonography (EUS).
  • The malignant grade of the GISTs was evaluated by the mitotic rate, tumor size, and MIB-1 index.
  • EUS was useful for differentiating benign from malignant GISTs; but by limiting the study to patients with small tumors (< 3 cm), the diagnostic value of EUS was not satisfactory for defining the surgical indication.
  • Tumors that were < 50 mm were successfully treated by laparoscopic surgery.
  • Of the 31 patients, 4 had a relapse of the disease, and 1 of those 4 patients had a small tumor (30 mm).
  • Surgery is indicated for gastric GISTs that are > or = 20 mm or are suspected to be malignant based on EUS findings.
  • Laparoscopic resection is feasible and is recommended as the treatment of choice for patients with tumors < 50 mm.
  • [MeSH-major] Gastrointestinal Stromal Tumors / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Aged. Endosonography. Female. Humans. Laparoscopy. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Retrospective Studies

  • Genetic Alliance. consumer health - Gastrointestinal Stromal Tumors.
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  • (PMID = 16369707.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Burzykowski T, Bang Y, GASTRIC project: Disease-free survival as a surrogate endpoint for overall survival in an adjuvant trial of curatively resected stomach cancer using individual patient data meta-analysis. J Clin Oncol; 2009 May 20;27(15_suppl):4517

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Disease-free survival as a surrogate endpoint for overall survival in an adjuvant trial of curatively resected stomach cancer using individual patient data meta-analysis.
  • DFS is defined as recurrence of stomach cancer, all second cancers, or death from any cause.
  • We evaluated 3 year DFS as a surrogate for 5 year OS in adjuvant trials of stomach cancer by using individual-patient data (IPD) meta- analysis validation criteria.
  • METHODS: The GASTRIC group initiated an IPD meta-analysis of all randomized clinical trials comparing chemotherapy versus surgery alone for patients with curatively resected stomach cancer.

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  • (PMID = 27962696.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Hoque E, Karim S, Hossen M, Ahmed TU: Study to see the efficacy and toxicity profile of docetaxel-based chemotherapy in advanced stomach cancer in Bangladeshi patient population. J Clin Oncol; 2009 May 20;27(15_suppl):e15687

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study to see the efficacy and toxicity profile of docetaxel-based chemotherapy in advanced stomach cancer in Bangladeshi patient population.
  • : e15687 Background: Gastric cancer is the second most common cause of cancer death worldwide.
  • Advanced gastric cancer patients have a poor prognosis of 3 to 5 months.
  • Docetaxel has shown activity against gastric cancer as monotherapy and in combination with other agents.
  • The purpose of this study was to investigate the efficacy and toxicity profile of docetaxel based chemotherapy in advanced stomach cancer in Bangladeshi patient population.
  • METHODS: From January 2004 to December 2006, thirty patients with advanced inoperable gastric cancer (Gastric or esophagogastric adenocarcinoma) were included in the study.
  • The primary end point was time to tumour progression.
  • RESULTS: Among the 30 evaluable patients time to tumour progression was 11.5 months.
  • CONCLUSIONS: Adding docetaxel to CF regimen significantly improved time to tumour progression and survival rate in advanced gastric cancer patients.
  • Docetaxel in combination with Cisplatin and 5-fluorouracil is a very safe and active in patients of Bangladesh with advanced gastric cancer.

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  • (PMID = 27962798.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Koucky K, Boxberger F, Albrecht H, Maennlein G, Wolff K, Ostermeier N, Schildberg C, Golcher H, Hohenberger W, Hahn EG, Wein A: Downsizing after palliative systemic chemotherapy with weekly high-dose 5-fluorouracil (5-FU) as a 24h-infusion and sodium folinic acid (AIO regimen) plus irinotecan in patients with metastatic adenocarcinomas of the stomach or the gastro-esophageal junction followed by secondary metastatic resection. J Clin Oncol; 2009 May 20;27(15_suppl):e15585

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Downsizing after palliative systemic chemotherapy with weekly high-dose 5-fluorouracil (5-FU) as a 24h-infusion and sodium folinic acid (AIO regimen) plus irinotecan in patients with metastatic adenocarcinomas of the stomach or the gastro-esophageal junction followed by secondary metastatic resection.
  • METHODS: 76 chemonaive patients (pts.) with histologically proven metastatic adenocarcinomas of the stomach or AEG tumours (tum.
  • ) (UICC IV), deemed to be non-resectable by the Interdisciplinary Tumour Board (ITB), were enrolled from 08/99 to 12/08.
  • This collective is presented here evidencing the efficacy of this interdisciplinary procedure in palliative (pall.) treatment of gastric cancer.
  • RESULTS: Last date of evaluation: Dec/31/2008; median age: 58,7 years; men/women: n=12/4; res. of the primary tum. prior to pall. chemoth.: yes/no: n=2/14, ECOG 0/1: n=5/11; primary tum. localisation: AEG tum.: n=7; gastric carcinoma: n=9, elevated CEA yes/no: n=5/11, elevated CA19-9 yes/no: n=5/11.

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  • (PMID = 27962360.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Chatterjee A, Bhattacharya S, Chatterjee AK, Biswas J, Mukhopadhyay B: A prospective observational clinical study involving an alternative cancer treatment, psorinum therapy, in treating stomach, gallbladder, pancreas, and liver cancers. J Clin Oncol; 2009 May 20;27(15_suppl):3050

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A prospective observational clinical study involving an alternative cancer treatment, psorinum therapy, in treating stomach, gallbladder, pancreas, and liver cancers.
  • : 3050 Background: The prospective observational clinical study was conducted to know the efficacy of an alternative cancer treatment, 'psorinum therapy,' in treating liver, gall bladder, pancreatic, and stomach cancers.
  • The primary outcome measures of the study were (1) to assess the radiological tumor response;.
  • METHODS: The drug psorinum (an alcoholic extract of scabies, scrub, slough, and pus cells) was administered orally at 0.01ml-0.02 ml/Kg body weight as a single dose in empty stomach per day and ongoing to all the participants along with allopathic and homeopathic supportive cares.
  • RESULTS: 158 histopathology or cytopathology proved participants (42 of stomach, 40 of gallbladder, 44 of pancreas, and 32 of liver cancers) were included in the final analysis at the end of the study.
  • According to the RECIST criteria, complete tumor response occurred in 28 (17.72%) cases and partial tumor response occurred in 56 (35.44%) cases.
  • CONCLUSIONS: Psorinum therapy is effective in treating stomach, gallbladder, pancreas, and liver cancers.

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  • (PMID = 27961982.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Sawaki A, Mizuno N, Takagi T, Hara K, Nakamura T, Tajika M, Kawai H, Matsumoto K, Kobayashi Y, Yamao K: Gastric submucosal tumors: Lessons learned from 10-year follow-up. J Clin Oncol; 2009 May 20;27(15_suppl):e15631

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric submucosal tumors: Lessons learned from 10-year follow-up.
  • : e15631 Background: Gastric Submucosal tumors (SMTs) were incidentally discovered esophagogastroduodenoscopy (EGD).
  • The aim of this study is to clarify the clinical features and long-term outcomes of gastric SMT at a single institute for 10-year period.
  • METHODS: We performed a total of 5307 EGDs and detected 188 gastric SMTs during 1998.
  • All clinical data including incidence, size and location in stomach were analyzed for the medical records.
  • RESULTS: Gastric SMTs were detected 188 (81 males, 107 females) of 5307 patients (3.5%).
  • 56% of SMTs located middle one third of stomach, and half (22%) of the remaining SMTs were detected at upper and lower one third, respectively.
  • Both of them underwent surgical resection and diagnosed as gastrointestinal stromal tumors (GIST).
  • CONCLUSIONS: The incidence of SMTs is 3.5%, majority (91%) is small (<2cm), and frequent location is middle one third of stomach.

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  • (PMID = 27962746.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Koh Y, Kim H, Lee H, Lee K, Oh D, Kim J, Im S, Kim T, Kim W, Bang Y: KIT and PDGFRAmutation status and their immunohistochemical (IHC) expression profile of gastrointestinal stromal tumor (GIST) patients treated with imatinib (IMT): Seven-year single-center experience. J Clin Oncol; 2009 May 20;27(15_suppl):10558

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] KIT and PDGFRAmutation status and their immunohistochemical (IHC) expression profile of gastrointestinal stromal tumor (GIST) patients treated with imatinib (IMT): Seven-year single-center experience.
  • Tumor DNA was extracted to investigate the mutation status of KITexon 9, exon 11, PDGFRA exon 12 and 18.
  • Location of primary disease included stomach (33), small bowel (34), rectum (10), esophagus (1), and omentum/mesentery (7).

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  • (PMID = 27963944.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Kanzler S, Trarbach T, Seufferlein T, Kubicka S, Lordick F, Geissler M, Daum S, Galle PR, Moehler M, German Arbeitsgemeinschaft Internistische Onkologie (AIO): Cetuximab with irinotecan/folinic acid/5-FU as first-line treatment in advanced gastric cancer: A nonrandomized multicenter AIO phase II study. J Clin Oncol; 2009 May 20;27(15_suppl):4534

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cetuximab with irinotecan/folinic acid/5-FU as first-line treatment in advanced gastric cancer: A nonrandomized multicenter AIO phase II study.
  • : 4534 Background: Cetuximab has demonstrated high efficacy in combination with irinotecan-based therapies in metastatic colorectal cancer and irinotecan/folinic acid/5-FU (IF) may be an effective alternative to cisplatin-based regimens in advanced gastric cancer.
  • We therefore conducted a phase II AIO study to evaluate the tolerability and efficacy of cetuximab combined with IF as first-line treatment in patients with advanced gastric cancer.
  • METHODS: Patients (pts) were eligible with untreated adenocarcinoma of the stomach or oesophagogastric junction, with ECOG performance status (PS) < 2, measurable lesions and adequate organ functions.
  • Treatment was continued until tumor progression and tumor assessments were performed every 2nd cycle.
  • RESULTS: Between Aug 2006 and Sep 2007, 49 pts were enrolled: 71% were males, median age was 63 years (range 33-77), median PS was 0 (65% pts), and 69% of pts and 31% of pts had gastric and oesophagogastric junction carcinomas, respectively.
  • Among 48 response-evaluable pts, the overall response rate (CR + PR) was 42% (CR 4%/PR 38%) and the tumour control rate was 73%.
  • Cetuximab combined with chemotherapy in advanced or metastatic gastric cancer is under further investigation in an ongoing phase III trial.

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  • (PMID = 27962992.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Yoon J, Cho S, Bae W, Hwang J, Shim H, Chung I: Phase II study of irinotecan, 5-fluorouracil (5-FU) and leucovorin combination chemotherapy in taxane and cisplatin-based chemotherapy-refractory metastatic gastric cancer. J Clin Oncol; 2009 May 20;27(15_suppl):e15599

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II study of irinotecan, 5-fluorouracil (5-FU) and leucovorin combination chemotherapy in taxane and cisplatin-based chemotherapy-refractory metastatic gastric cancer.
  • : e15599 Background: The role of the second line chemotherapy in advanced gastric cancer was not clear, but possibility of prolongation of survival is open question.
  • Irinotecan is promising agents in gastric cancer and this phase II study evaluated the efficacy and safety of combination chemotherapy with irinotecan, high dose of 5-fluorouracil (5-FU) and leucovorin in taxane and cisplatin based chemotherapy refractory metastatic gastric cancer.
  • METHODS: Eligible criteria were as followed; histologic confirmed adenocarcinoma of stomach, previously treated with taxane and cisplatin, age≥18, Eastern Clinical Oncology Group (ECOG) performance status of 1 or less, adequate organ function.
  • All patients were evaluable for safety and survival and twenty seven patients (79.4%) were evaluable for tumor response.

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  • (PMID = 27962881.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Bogoevski D, Schurr PG, Koenig AM, Busch P, Kutup A, Izbicki JR: Is there still place for endoscopic mucosal resection in patients with early oesophageal carcinomas? J Clin Oncol; 2009 May 20;27(15_suppl):e15640

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • None of the 43 patients with high grade intraepithelial neoplasia (HGIEN) or oesophageal carcinoma limited to the mucosa had lymphatic spread, as compared with 15 of 68 (22.1%) with affection of the submucosa.
  • Multifocal neoplasia was detected in three patients with SCC HGIEN (30%) but not in AC HGIEN!
  • Nine out of 44 (20.4%) patients with early SCC had multifocal neoplasia, compared to 6 out of 53 (11.3%) patients in AC (p=0.322).
  • The sensitivity of the preoperative tumour dept staging (endoscopic ultra sound - EUS; and CT) was astonishing low (only 50% for cT1b), as was the specificity (66.7% for cT1a and only 87.5% for cT1b).
  • On multivariate analysis, only histological tumor type (AC) was independent predictor of survival.
  • A valuable alternative can be the limited resection of the oesophago-gastric junction under sparing of the healthy oesophagus and stomach.

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  • (PMID = 27962740.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Bukhari MH, Byron E, Strosberg JR, Nasir NA, Henderson-Jackson E, Bui M, Hakam A, Domenico C, Kvols L, Nasir A: Primary gastroenteropancreatic poorly differentiated neuroendocrine carcinoma: Clinico-pathologic analysis of 68 cases. J Clin Oncol; 2009 May 20;27(15_suppl):e15616

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15616 Background: Primary gastro-entero-pancreatic poorly differentiated neuroendocrine carcinomas (GEP-PDNECAs) are highly aggressive neoplasms with a very poor prognosis.
  • DATA SOURCES: Pathology archives, consultation files, tumor registry and social security index.
  • All available slides were reviewed and tumors were histologically sub-typed.
  • Sites: Colo-rectum 39, pancreas 19, small intestine (SI) 4, stomach 3, colon/SI/pancreas 3.
  • Of 68 tumors 37 (54%) were classified as small cell carcinoma (SCCA), 16 (24%) large cell carcinoma (LCCA), 5 (7%) mixed small and large cell (MSLCCA) and 10 (15%) poorly differentiated carcinoma with neuroendocrine features (PDCA-NEF).
  • Tumors were positive for chromogranin in 38/65 (55%), synaptophysin in 62/67 (92%), and CD56 in 17/21 (81%) cases.
  • CONCLUSIONS: Diagnosis of GEP-PDNECA can be based on histo-morphologic features and expression of neuroendocrine markers.
  • Synaptophysin was the most sensitive marker; however, a panel of 2 or 3 neuroendocrine markers (Syn, Cg and CD56) may be more useful to avoid under-diagnosis of GEP-PDNECA, especially in the metastatic setting.

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  • (PMID = 27962728.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Macdonald JS, Benedetti J, Smalley S, Haller D, Hundahl S, Jessup J, Ajani J, Gunderson L, Goldman B, Martenson J: Chemoradiation of resected gastric cancer: A 10-year follow-up of the phase III trial INT0116 (SWOG 9008). J Clin Oncol; 2009 May 20;27(15_suppl):4515

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chemoradiation of resected gastric cancer: A 10-year follow-up of the phase III trial INT0116 (SWOG 9008).
  • : 4515 Background: INT0116 (SWOG 9008) was a prospectively randomized phase III trial of postoperative adjuvant therapy utilizing 5-FU/leucovorin plus external beam radiation in 582 eligible cases of resected stage IB-IV(M0) stomach and gastroesophageal junction cancers.
  • Subset analyses were performed for sex, race, T and N stage, D-level of surgical resection, tumor location (proximal or other), histology (intestinal or diffuse) and Maruyama index.
  • Thirty-five second tumors occurred in 31 cases.
  • Second tumors represented a spectrum of types of neoplasms commonly occurring in this age group (median age 60 years).
  • Excessive numbers of tumors known to be caused by radiation and/or chemotherapy were not noted.
  • More tumors may have occurred in the treated patients since their death rates were less than surgery only cases.
  • CONCLUSIONS: With >10 years median follow-up, survival remains improved in stage IB-IV (M0) gastric cancer cases treated with post-operative chemoradiaiton.
  • Women may be more likely to have diffuse histology gastric cancers.

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  • (PMID = 27962700.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Jhawer M, Kindler HL, Wainberg Z, Ford J, Kunz P, Tang L, McCallum S, Kallender H, Shah MA, MET111643 Investigators and GlaxoSmithKline: Assessment of two dosing schedules of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in metastatic gastric cancer (GC): Interim results of a multicenter phase II study. J Clin Oncol; 2009 May 20;27(15_suppl):4502

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of two dosing schedules of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in metastatic gastric cancer (GC): Interim results of a multicenter phase II study.
  • METHODS: Pts with distal esophagus, GE junction or stomach adenocarcinoma, 0-2 prior chemotherapy regimens, adequate organ function, measurable disease, and ECOG PS 0-2 are sequentially enrolled in 2 cohorts:.
  • Pre- and on-treatment tumor biopsies in select pts and plasma samples in all pts are analyzed for GSK089 effects on direct and downstream drug targets.
  • Single agent GSK089 demonstrates minimal antitumor activity in a cMET-unselected gastric population on the 5 on/9 off schedule.

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  • (PMID = 27962690.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Bose P, Thompson CL, Gandhi DG, Ghabach BS, Ozer H: Response of AIDS-related plasmablastic lymphoma (PBL) to bortezomib. J Clin Oncol; 2009 May 20;27(15_suppl):e19562

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e19562 PBL are a group of highly aggressive neoplasms originally described in the oral cavity and jaws of HIV-infected patients.
  • They are terminally differentiated B-cell neoplasms, and typically lack common B-cell markers but uniformly express plasma cell markers.
  • EGD with biopsy revealed a high-grade PBL of the stomach.
  • The diagnosis was stage IVBE PBL.
  • However, studies of their immunophenotype and molecular histogenesis suggest that PBL are more closely related to plasma cell neoplasms.

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  • (PMID = 27961065.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Aguiar Bujanda D, Bohn Sarmiento U, Saura Grau S, Rodriguez Franco C, Aguiar Morales J: Clinical activity of rituximab with either CHOP or CVP in MALT lymphoma. J Clin Oncol; 2009 May 20;27(15_suppl):e19530

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with gastric MALT lymphoma were included if resistant to or not eligible for anti-Helicobacter pylori therapy.
  • Primary origin: 14 stomach (64%), 3 skin, and 5 others (nodal, parotid gland, orbital, colon, and lung).
  • Patients with gastric lymphoma did not have bleeding or perforation during therapy.
  • Patients with gastric lymphoma (n=14) showed an ORR of 93% (CR 86%, PR 7%, SD 7%).
  • Radiation therapy was given as consolidation after chemotherapy to 3 patients with extra-gastric origin.
  • With a median follow-up of 28 months, two patients (gastric lymphoma) have relapsed at 4 and 12 months respectively.

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  • (PMID = 27961030.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Cadoo KA, Lowery MA, Cumiskey J, McCaffrey J, Carney DN: Long term follow-up of primary B and T cell non-Hodgkin's lymphoma (NHL) of the gastrointestinal (GI) tract. J Clin Oncol; 2009 May 20;27(15_suppl):e19516

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Median age at diagnosis was 60 (15-83).
  • Primary sites of DLBCL were stomach 35 (67%), small bowel 11 (21%) & colon 6 (12%).
  • 39 (62%) patients underwent surgery at diagnosis due to acute presentation with perforation, bleeding or obstruction, or to obtain histology.
  • Following confirmed diagnosis, 61 patients received anthracycline based chemotherapy.

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  • (PMID = 27960953.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Hohenberger P, Oladeji O, Licht T, Dimitrakopoulou-Strauss A, Jakob J, Pink D, Schwarzbach M, Ströbel P, Reichardt P, Wardelmann E: Neoadjuvant imatinib and organ preservation in locally advanced gastrointestinal stromal tumors (GIST). J Clin Oncol; 2009 May 20;27(15_suppl):10550

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoadjuvant imatinib and organ preservation in locally advanced gastrointestinal stromal tumors (GIST).
  • : 10550 Background: We assessed the outcome of patients with locally advanced gastrointestinal stromal tumors (GIST) undergoing preoperative therapy with imatinib.
  • METHODS: 36 patients with biopsy proven GIST (23 f, 13 m, median age 58 (27-85) yrs, 31 primary tumors, 5 local recurrences) of the esophagus/EGJ (n=5), stomach (n=17), duodenum (n=2), small bowel (n=3), or rectum (n=9) were treated with imatinib 400mg/d for 6 mos. preop.
  • Average tumor size was 10.5 cm (4-28 cm).
  • According to Consensus two tumors were low risk, 11 intermediate, and 23 were high risk for aggressive behaviour.
  • 33 pts. completed the treatment schedule, two died from unrelated disease, another one had to be operated for tumor rupture.
  • Of the remaining 33, median tumor size shrank to 55 mm.
  • Complete tumor removal was possible in 28 pts without operative mortality, but two pts showed previously undetected peritoneal spread (R2 resection).
  • The extent of resection found 5 of 6 inoperable pts now resectable and in 21/25 pts a less extensive procedure could be performed in comparison to recommendations by previous tumor boards (segmental gastric resection for gastrectomy, avoidance of pancreatectomy, transanal resection instead of colo-anal anastomosis).
  • Substantial tumor shrinkage facilitates radical but conservative surgery and results in organ-preservation in the overwhelming majority of patients.

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  • (PMID = 27963946.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Emile François J, Brahimi S, Coindre J, Monges G, Scoazec JY, Blay J, Bouché O, Aegerter P: Molecular epidemiology of GISTs: Incidence of PDGFRA and KIT exon 9 mutations in the large French population-based study molecGIST. J Clin Oncol; 2009 May 20;27(15_suppl):10535

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : 10535 Background: KIT exon 11, KIT exon 9, and PDGFRA exon 18 mutations are present in 67%, 10% and 5% of gastrointestinal stromal tumors (GIST).
  • However most of these data are based on analyses of patients with overtly metastatic tumors.
  • METHODS: All patients leaving in France, whose diagnosis of GIST was achieved between June 1, 2006 and May 31, 2008 were includable in the study.
  • The median age at diagnosis 63.1 years (range [15-96]), and female/male ratio 0.98.
  • GIST originated in the stomach in 56.3% and small bowel in 29.3% of the cases.
  • Tumors were KIT+ in 90,4% of cases.
  • CD34 was expressed by more than 20% of tumor cells in 83.8% of gastric GIST and 39.7% of small bowel GIST respectively (P<0.0001).

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  • (PMID = 27963887.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Conley AP, Araujo D, Ludwig J, Ravi V, Samuels BL, Choi H, Thall PF, Patel S, Benjamin R, Trent J: A randomized phase II study of perifosine (P) plus imatinib for patients with imatinib-resistant gastrointestinal stromal tumor (GIST). J Clin Oncol; 2009 May 20;27(15_suppl):10563

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A randomized phase II study of perifosine (P) plus imatinib for patients with imatinib-resistant gastrointestinal stromal tumor (GIST).
  • The most common primary site of disease and metastasis was the stomach (29%) and liver (66%), respectively.

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  • (PMID = 27963814.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Kang B Sr, Lee J, Ryu M, Im S, Park S, Kang W, Kim T, Oh D, Jung K, Kang Y: A phase II study of imatinib mesylate as adjuvant treatment for curatively resected high-risk localized gastrointestinal stromal tumors. J Clin Oncol; 2009 May 20;27(15_suppl):e21515

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A phase II study of imatinib mesylate as adjuvant treatment for curatively resected high-risk localized gastrointestinal stromal tumors.
  • : e21515 Background: In our previous study, the presence of c-kit mutation as well as tumor size and mitotic count was an independent poor risk factor for relapse after curative resection of primary localized GIST.
  • METHODS: Patients who underwent complete resection of a primary GIST with 1) c-kit exon 11 mutation, and 2) ≥10 mitoses/50 HPF, or tumor size ≥10 cm, or ≥5 mitoses/50 HPF and tumor size ≥5 cm were eligible.
  • Stomach was the most common primary site (n=31).
  • Median primary tumor size was 7.5cm and median mitoses index was 12/50 HPF.

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  • (PMID = 27963446.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Buyse ME, Pignon J, GASTRIC: Meta-analyses of randomized trials assessing the interest of postoperative adjuvant chemotherapy and prognostic factors in gastric cancer. J Clin Oncol; 2009 May 20;27(15_suppl):4539

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meta-analyses of randomized trials assessing the interest of postoperative adjuvant chemotherapy and prognostic factors in gastric cancer.
  • : 4539 Background: Despite potentially curative resection of stomach cancer, 50%-90% of patients die of disease relapse.
  • Our group has initiated an individual patient data (IPD)-based meta-analysis of all RCTs in the adjuvant gastric setting to quantify the potential benefit of S+CT over S, to study the role of various prognostic factors and their potential interactions with treatments.
  • Baselines variables included age, sex, tumour size (T) and stage, type of resection (D0, D1, D2 or more), performance status (PS) and geographic area.
  • CONCLUSIONS: Our interim results show a modest but significant OS benefit in favour of adjuvant CT and confirm the impact of tumour staging as well as age and PS on OS.

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  • (PMID = 27962986.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Wade FM, Pavlakis N, Receveur I, Leibman S, Smith GS: The role of cancer Nurse coordinator in foregut malignancy: Workload and costing considerations in the Australian setting. J Clin Oncol; 2009 May 20;27(15_suppl):e20559

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e20559 Background: Foregut (esophageal and gastric) malignancy (FM) encompasses a number of diseases with poor outlook and complex and often morbid treatment.
  • Further, the CNC is pivotal in ensuring that benchmarks regarding intervals from diagnosis, to multidisciplinary assessment to treatment commencement are met.
  • The number of cancers arising from the esophagus or esophagogastric junction was 135 (62%), stomach 78 (36%) and small bowel 5 (2%).

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  • (PMID = 27961033.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Haid A, Knauer M, Köberle-Wührer R, Wenzl E: Sentinel node biopsy in breast cancer: technique and indication. Wien Klin Wochenschr; 2005 Feb;117(4):121-128

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : Sentinel node biopsy (SNB) has proved to be a useful and accurate procedure for lymph node staging in breast cancer and melanoma and should be standard of care in the treatment of these tumors.
  • In other malignancies (colon, rectum, stomach, esophagus, head and neck and thyroid, cervix uteri) it is still under investigation.
  • Accepted indications are uni- and multifocal tumors smaller than 3 cm without suspicious findings in the axilla, furthermore SNB is indicated in patients with large ductal carcinoma in situ (>2 cm) and/or with assumed microinvasion.

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  • (PMID = 28108807.001).
  • [ISSN] 1613-7671
  • [Journal-full-title] Wiener klinische Wochenschrift
  • [ISO-abbreviation] Wien. Klin. Wochenschr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
  • [Keywords] NOTNLM ; Breast cancer / Indications / Sentinel node biopsy / Technique
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41. Saponara M, Di Battista M, Lolli C, Derenzini E, Pantaleo MA, Santini D, Ceccarelli C, Catena F, Nannini M, Maleddu A, Biasco G: Evaluation of Ki-67 in gastrointestinal stromal tumor (GIST). J Clin Oncol; 2009 May 20;27(15_suppl):e21510

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of Ki-67 in gastrointestinal stromal tumor (GIST).
  • The two canonical parameters used for the prediction of GISTs' prognosis are tumor size and mitotic index.
  • Twenty-six cases arose from stomach and 15 from small bowel.
  • The expression of this cell-cycle related protein was correlated with tumor site (stomach; any other site), dimensions (<5 cm; >=5cm), mitotic index (<=5/50 HPFs; >5/50 HPFs), standard risk groups (low; intermediate-high) and disease free survival (DFS).
  • RESULTS: Ki-67 over-expression was positively correlated with tumor size >=5cm (p= 0.035).
  • Lower levels of Ki-67 expression have been observed in gastric GISTs compared to any other site (29 cases with Ki-67 <=10% of which 21 gastric and 8 in other sites), even if these values were not statistically significant (p = 0.527).

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  • (PMID = 27963442.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Boers JE, Meeuwissen H, Methorst N: HER2 status in 146 gastroesophageal carcinomas assessed by two rabbit monoclonal antibodies (SP3 and 4B5) and two in situ hybridisation methods (FISH and SISH). J Clin Oncol; 2009 May 20;27(15_suppl):e15555

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15555 Background: In the industrialized world, the incidence of adenocarcinomas of the distal esophagus/gastric cardia is increasing rapidly and though the incidence of carcinomas of the gastric body / antrum are decreasing they still represent a significant health problem.
  • A large phase III trial in which HER2-positive gastric cancer patients are treated with trastuzumab is ongoing.
  • RESULTS: IHC was carried out on biopsies of 146 patients with adenocarcinomas of the esophagus (n=44), gastric cardia (n=28), body (n=24) and antrum (n=50).
  • Heterogenous HER2- positivity with partial staining/amplification was present in 73% of the adenocarcinomas, occasionally with only a tumor area of 10-20% showing positivity.
  • HER2-amplification was present in 27% of esophageal and 18% in gastric cardia carcinomas (resulting in 24% amplification of tumors of the esophago-gastric region).
  • In the distal stomach, 7% HER2-amplification was seen.
  • CONCLUSIONS: HER2 amplification is present in a significant proportion of esophago-gastric region adenocarcinomas (24%) but at a much lower rate in the distal stomach (7%).

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  • (PMID = 27962336.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Servarayan CM, Chandramohan A, Datta D, Manickavasagam K: p53 and its influence in adenocarcinoma stomach. J Clin Oncol; 2009 May 20;27(15_suppl):e15685

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p53 and its influence in adenocarcinoma stomach.
  • : e15685 Background: Gastric cancer is the second most common cause of the malignancy in the world after lung cancer.
  • METHODS: This is a immunohistochemical prospective experiment study done on 76 cases of Gastric Adenocarcinoma.The location of the tumors were recorded as in the proximal stomach (fundus and body) and distal stomach (antrum, prepylorus, and pylorus).
  • 33 out of 60 (55%)of the males and 8 out of 16 (50%) females were reported of having gastric adenocarcinoma with p53expression.
  • The histology of the tissue samples from the gastric adenocarcinoma patients had following relationship with the p53 immunoreactivity, 20 out of 37 cases(54.05%) of the well differentiated,7 out of 17 cases (41.18% )of the moderately differentiated, and and 13 out of 21 cases(61.90%) of the poorly differentiated gastric adenocarcinoma showed positive immunoreactivity.
  • 15 out of 33 cases (45.45%)were localized to the proximal stomach and 30 out of 52 cases (57.69%)were localized to the distal stomach.
  • 52.63 % of the non-mucinous type of gastric adenocarcinoma showed positive p53 immunoreactivity.
  • The mutation is more marked in the poorly differentiated gastric adenocarcinoma.
  • The antral, pylorus,and the prepyloric parts of the stomach( the distal stomach) are more prone for mutated p53 induced adenocarcinoma.

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  • (PMID = 27962795.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Aggarwal S, Prakhar P, Kohli S, Negi A, Jauhari M, Bhalla S: Retrospective analysis and chemotherapy results in extra-nodal NHL patients in a large super-speciality hospital in North India. J Clin Oncol; 2009 May 20;27(15_suppl):e19566

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Out of 77 extra-nodal cases, 31(20%) were GIT NHL (Stomach -16, Colon-8, Ileum-4, and Duodenum-3) and out of the rest 46 extra-nodal cases the site of origin was - head & neck-14, skin n soft tissues -8, primary CNS-6, testicular-4, para-spinal- 3, breast mass-3, perinephric-2, bones-2 and 1 each in cervix, lung mass, liver and cervical plexus.
  • No surgery was performed in patients with stomach lymphoma.

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  • (PMID = 27961061.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Di Battista M, Saponara M, Pantaleo MA, Catena F, Santini D, Lolli C, Di Scioscio V, Astorino M, Maleddu A, Nannini M, Biasco G: Microscopic margins of resection in gastrointestinal stromal tumor (GIST): An analysis of 122 patients. J Clin Oncol; 2009 May 20;27(15_suppl):10554

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microscopic margins of resection in gastrointestinal stromal tumor (GIST): An analysis of 122 patients.
  • The prognosis is strongly correlated with both tumor size and mitotic index.
  • The most common sites of tumor origin were the stomach (54.9%) and the small bowel (36.9%).
  • Sites of tumor metastasis were liver (18.2%), peritoneum (36.4%) or both (19.3%).

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  • (PMID = 27963950.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Siemerink E, Schaapveld M, Hospers GA, Mulder NH, Plukker JT: Effect of hospitals on survival and postoperative mortality of stomach cancer: A population-based study on type, referral, and volume-effect in the northeast Netherlands. J Clin Oncol; 2009 May 20;27(15_suppl):e15564

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of hospitals on survival and postoperative mortality of stomach cancer: A population-based study on type, referral, and volume-effect in the northeast Netherlands.
  • : e15564 Background: To optimize treatment results of patients with stomach cancer some institutions prompt referral to high volume hospitals with experienced surgeon's analogue to esophageal cancer.
  • METHODS: Data from all patients diagnosed with primary invasive stomach cancer from 1994-2006 were obtained from the nationwide Netherlands Cancer Registry of the north-east part of the Netherlands.
  • RESULTS: In the study period, 5243 patients were diagnosed with stomach cancer (65.6% men, 34.4% female), 44.5% underwent surgery.
  • Older age, advanced stage and proximal tumor location resulted in a lower probability of tumor resection.
  • However, patients with proximal tumors were more often referred for surgery to U (18%), especially by N-T hospitals.
  • In the non-proximal tumors the 5yrsurv was significantly better in U versus T and N-T hospitals, also after multivariate analysis.
  • CONCLUSIONS: We found highly superior survival for non-proximal tumors but not for proximal cancer in an university hospital.

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  • (PMID = 27962324.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Stintzing S, Hoffmann RT, Heinemann V, Kufeld M, Muacevic A: Robotic radiosurgery of liver metastases of solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):e15049

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Robotic radiosurgery of liver metastases of solid tumors.
  • We here report the therapeutic efficacy of a robotic radiosurgery device for local control of liver metastases of solid tumors.
  • METHODS: Patients with liver metastases not qualifying for surgery were treated with single session radiosurgery (24 Gy) using robotic image-guided real-time tumor tracking.
  • For inclusion into the radiosurgery treatment protocol, tumor volumes had to be smaller than 80cc.
  • Metastases (n=27) originated from: colon (12), rectum (2), pancreas (2), lung (1), bladder (2), malignant melanoma (1), stomach (1), cholangiocellular carcinoma (2), breast (1), ovary (1), appendix (1) and endometrium (1).
  • Median tumor volume was 21cc (range 2.2-79.3).
  • CONCLUSIONS: Robotic radiosurgery with image-guided real-time tumor tracking of liver metastases is a new and promising treatment approach for pts not eligible for surgical resection and might enhance the possibilities of multidisciplinary oncological treatment concepts.

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  • (PMID = 27964438.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Wozniak A, Rutkowski P, Debiec-Rychter M, Siedlecki J, Michej W, Osuch C, Matlok M, Ruka W, Limon J, Polish Clinical GIST Registry: Spectrum of KIT and PDGFRA mutations in primary gastrointestinal stromal tumors: Polish Clinical GIST Registry experience. J Clin Oncol; 2009 May 20;27(15_suppl):e21504

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spectrum of KIT and PDGFRA mutations in primary gastrointestinal stromal tumors: Polish Clinical GIST Registry experience.
  • : e21504 Background: KIT or PDGFRA gene mutations are found in 80-90% of gastrointestinal stromal tumors (GIST).
  • The prognostic value of those mutations for the outcome in primary tumors is controversial.
  • RESULTS: KIT/PDGFRA genes mutations were found in 82% tumors: KIT was mutated in 69% and PDGFRA in 13% of tumors.
  • KIT exon 11 mutations were found at the similar rates in tumors with gastric and non-gastric localization (53.9% vs. 46.1% respectively) while KIT exon 9 duplications were more often observed in non-gastric GISTs (86.4%, p=0.00036) and PDGFRA mutations were more frequently found in tumors originated from the stomach (86.8%; p=0.00017).
  • In high risk tumors KIT exon 11 deletions were more frequently found than point mutations (p=0.017).
  • No significance of mutations for disease outcome after surgery of primary tumors was found.

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  • (PMID = 27963396.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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54. Salerrno May KS, Yang GY, Iyer RV, Chandrasekhar R, Wilding G, Khushalani NI, Yendamuri SS, Gibbs JF, Fakih M: Renal atrophy secondary to chemoradiation treatment of abdominal malignancies. J Clin Oncol; 2009 May 20;27(15_suppl):e15532

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Primary disease sites were pancreas (61.5%), periampullary (16.1%), stomach (10.8%), gastroesophageal junction (10%), and retroperitoneum (1.5%).

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  • (PMID = 27962316.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Pitot HC, Mould D, Maleski J, Leopold L: Analysis of a phase I pharmacokinetic (PK)/food effect study of AT-101 in patients with advanced solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):2557

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Analysis of a phase I pharmacokinetic (PK)/food effect study of AT-101 in patients with advanced solid tumors.
  • Cohort A received AT-101 (80 mg) orally on day 1 on an empty stomach (fasted) and again on day 8 with a high fat high calorie breakfast (fed), per FDA guidelines.

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  • (PMID = 27961871.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Santoro J, Yorke E, Rosenzweig K, Goodman K, McNamara J, Pham H, Mageras G: Abstracts. Med Phys; 2010 Jun;37(6Part12):3090-3469

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: This study compares respiration-correlated kV cone beam CT (RC-kVCBCT) image guidance to standard (uncorrelated) kVCBCT for target localization in radiation treatment of thoracic and abdominal tumors.
  • METHOD AND MATERIALS: In an IRB-approved study, 9 stage II-IV non-small cell lung cancer (NSCLC) patients and 1 stage III stomach tumor patient with fiducials received a respiration-correlated planning CT (RCCT) at simulation and five RC-CBCTs during the first week of treatment.
  • The tumor in each phase of the RC-CBCT is registered to the end-expiration (EE) phase image to obtain the respiration-averaged tumor displacement relative to its EE position.
  • The RCCT and RC-CBCT images at EE are registered to obtain the tumor displacement at the EE position.
  • A vector sum of the three displacements yields the correction to the respiration-averaged tumor position.
  • CONCLUSION: Our preliminary results suggest that for many thoracic and abdominal tumors, position corrections using uncorrelated, respiration-averaged 3D imaging are consistent with those from respiration-correlated imaging; however, respiration-correlated imaging may be indicated for cases of large tumor motion.

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  • [Copyright] © 2010 American Association of Physicists in Medicine.
  • (PMID = 28512987.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cancer / Computed tomography / Cone beam computed tomography / Image reconstruction / Lungs / Medical image reconstruction / Medical imaging / Pneumodynamics / Radiation therapy / Radiation treatment
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57. Pendharkar D, Salim-Ul-Zaman H: Epidemiology of cancer in Afghanistan. J Clin Oncol; 2009 May 20;27(15_suppl):e22200

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • GE junction tumors were common as well.
  • The food is barbecued on wood and eaten without any spices.Similar analysis from similar altitude in Kashmir region of India, had shown very high incidence of GE junction and stomach cancer.

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  • (PMID = 27964129.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Lee H, Yuh Y, Kim S: Serum lactate dehydrogenase (LDH) level as a prognostic factor for the patients with advanced gastric cancer. J Clin Oncol; 2009 May 20;27(15_suppl):e15621

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serum lactate dehydrogenase (LDH) level as a prognostic factor for the patients with advanced gastric cancer.
  • : e15621 Background: Though serum LDH level is frequently elevated in the patients with advanced gastric cancer, its clinical significance is still elusive.
  • We analyzed serum LDH level as a prognostic factor for the patients with advanced stomach cancer.
  • CONCLUSIONS: For the patients with advanced gastric cancer, high serum LDH level was related to better response to chemotherapy but shorter survival duration.

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  • (PMID = 27962703.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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59. Aziz SA, Banday MA, Mir MH: Comparative efficacy of adjuvant chemoradiation versus chemotherapy in surgically resected adenocarcinoma of stomach. J Clin Oncol; 2009 May 20;27(15_suppl):e15639

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative efficacy of adjuvant chemoradiation versus chemotherapy in surgically resected adenocarcinoma of stomach.
  • : e15639 Background: Outcome of carcinoma of stomach has not changed over the past decades and surgery remains the time tested primary modality of treatment.
  • The present study focuses to compare the efficacy of adjuvant chemoradiation Vs Chemotherapy alone in surgically resected adenocarcinoma of stomach.

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  • (PMID = 27962750.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Pandurengan RK, Strom SS, Trent J 2nd: Gastrointestinal stromal tumor associated with other primaries: A study of 154 patients. J Clin Oncol; 2009 May 20;27(15_suppl):10567

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastrointestinal stromal tumor associated with other primaries: A study of 154 patients.
  • : 10567 Background: The objective of this study is to investigate the characteristics and survival rate of patients with Gastrointestinal Stromal Tumor (GIST) associated with other primary malignancies.
  • Multiple primaries included tumors that were not considered to be a metastasis, invasion or recurrence of GIST excluding non-melanoma skin cancer.
  • Data on gender, age at diagnosis of cancer, follow-up time after diagnosis, and death rate were collected.
  • Median age at diagnosis of GIST was 57 for patients with GIST only whereas it was 68 in patients with GIST+.
  • The stomach was the frequent site of occurrence in GIST only and GIST+.
  • The total numbers of other primaries developed before the diagnosis of GIST was higher (134) than the primaries developed after the diagnosis of GIST (53).
  • The most frequent primaries observed before the diagnosis of GIST were prostate (25), breast (12), esophagus (9), kidney (7) and melanoma (6).
  • Lung (5) and kidney (5) were the most frequent type of primaries that developed after the diagnosis of GIST.
  • The 5-yr survival was 68% for patients with GIST+ when the other primary occurred before GIST, 61% for patients with GIST+ when the other primary occurred after the diagnosis of GIST, 58% for patients with GIST only, and 49% for GIST++ patients with two or more other primaries (p=0.002).

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  • (PMID = 27963788.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Gansler T, Comis R, Sharpe K, Tis L, Jin M, Dahlquist K, Kepner J, Hao Y, Cressman G, Naples K: Initial results of a new clinical trial matching service to increase patient participation. J Clin Oncol; 2009 May 20;27(15_suppl):e17504

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the 757 individuals with available disease site and enrollment information, those with stomach cancer accounted for the most enrollments (25, 24.75% of all enrollments); followed by melanoma (12, 11.88%) and kidney, renal pelvis, bladder, ureter and urethra (also 12, 11.88%), and breast cancer (11, 10.89%).
  • Strategies for eliminating racial disparities, facilitating transportation, and increasing participation among patients with earlier stage disease and more common tumor types must be developed and implemented.

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  • (PMID = 27963240.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Hertz P, Seruga B, Le LW, Tannock IF: Global drug development in cancer: A cross-sectional study of clinical trial registries. J Clin Oncol; 2009 May 20;27(15_suppl):2520

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cancer sites that are major killers globally, and especially in the LDW (e.g., stomach, liver, and esophageal cancer) should receive priority for clinical research.

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  • (PMID = 27961846.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Hata Y, Ishigami S, Natsugoe S, Nakajo A, Okumura H, Miyazono F, Matsumoto M, Hokita S, Aikou T: P53 and MIB-1 expression in gastrointestinal stromal tumor (GIST) of the stomach. Hepatogastroenterology; 2006 Jul-Aug;53(70):613-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] P53 and MIB-1 expression in gastrointestinal stromal tumor (GIST) of the stomach.
  • BACKGROUND/AIMS: Routine clinical approaches for evaluating the risk of recurrence in patients with gastrointestinal stromal tumor (GIST) of the stomach have been limited.
  • METHODOLOGY: We enrolled 31 gastric GIST patients who underwent gastrectomy at Kagoshima University Hospital.
  • Patients were classified into two groups based on mitosis and tumor diameter. p53 and MIB-1 expression in the primary tumor were detected immunohistochemically.
  • RESULTS: The patients were classified as having a malignant GIST (20 cases), a benign GIST (11 cases).
  • The MIB-1 LI for malignant GISTs was 6.3 +/- 6.4%, which was significantly higher than the 3.2 +/- 2.5% observed for benign GISTs (p < 0.01).
  • Especially, p53 expression of the tumor may indicate patients having a high risk of recurrence.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Gastrointestinal Stromal Tumors / pathology. Ki-67 Antigen / metabolism. Stomach Neoplasms / pathology. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 16995473.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
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64. Sazhin VP, Naumov IA, Klimov DE, Nuzhdikhin AV: [Laparoscopic resection of the stomach by Billroth-I technique]. Khirurgiia (Mosk); 2005;(1):21-4

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  • [Title] [Laparoscopic resection of the stomach by Billroth-I technique].
  • Laparoscopic resection of the stomach by Billroth-I technique is described.
  • Previously different variants of laparoscopic Billroth-II resection and laparoscopy-assisted Billroth-I resection have been performed a complete variant of laparoscopic Billroth-I resection of the stomach the authors reported on Symposium of Endo-surgeons in 2004.
  • [MeSH-minor] Humans. Stomach Ulcer / surgery

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  • (PMID = 15699963.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Russia
  • [Number-of-references] 6
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65. Lam WW, Lee JS, Ho G: MRI: imaging of stomach. Australas Radiol; 2007 Oct;51(5):432-6
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  • [Title] MRI: imaging of stomach.
  • The study is to determine the optimal MRI bowel preparation regime for visualization of the stomach anatomy.
  • The image quality and tolerance of different stomach distension regime were evaluated.
  • Taking into account the image quality, tolerability and adverse effects, it is concluded that water is the most desirable oral contrast for MR stomach imaging.
  • [MeSH-major] Contrast Media / administration & dosage. Magnetic Resonance Imaging / methods. Stomach / anatomy & histology

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  • (PMID = 17803794.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Contrast Media; 059QF0KO0R / Water; 25BB7EKE2E / Barium Sulfate
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66. Saini N, Gupta M: Morphometry of myenteric neurons in stomach. Nepal Med Coll J; 2007 Jun;9(2):96-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphometry of myenteric neurons in stomach.
  • The musculature of fundus, body and pyloric parts of stomach are differently disposed and they perform different functions.
  • Thus the present study was conducted to study the myenteric plexus of all parts of stomach by counting the number of collections of neurons, number of neurons in each collection, diameter and area of the neurons of the plexus.
  • The stomach walls of 1 cm in size were taken from 5 cadavers of medical post mortem cases from Postgraduate Institute of Medical Sciences and Research, Chandigarh and were processed for paraffin sections.
  • [MeSH-major] Autonomic Nervous System / anatomy & histology. Gastric Fundus / innervation. Muscle, Smooth / innervation. Myenteric Plexus / anatomy & histology. Pylorus / innervation. Stomach / innervation

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  • (PMID = 17899957.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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67. Menon P, Rao KL, Bhasin S, Vanitha V, Thapa BR, Lal A, Vaiphei K: Giant isolated cavernous hemangioma of the stomach. J Pediatr Surg; 2007 Apr;42(4):747-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant isolated cavernous hemangioma of the stomach.
  • Giant isolate cavernous hemangiomas of the stomach are extremely rare.
  • An eight year old boy with recurrent episodes of massive hematemesis and involvement of both the anterior and posterior walls of the stomach is presented.
  • Awareness of the lesion, a combination of endoscopy and contrast enhanced CT scan are helpful in reaching a diagnosis.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Stomach Neoplasms / diagnosis

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  • [CommentIn] J Pediatr Surg. 2007 Sep;42(9):1634-5; author reply 1635-6 [17848268.001]
  • (PMID = 17448781.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Soybel DI: Anatomy and physiology of the stomach. Surg Clin North Am; 2005 Oct;85(5):875-94, v
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anatomy and physiology of the stomach.
  • In this article, key concepts in gastric anatomy and physiology are reviewed.
  • Attention is given to historical development of concepts of acid secretion, to the role of stomach in digestion, and to the mechanisms that protect gastric mucosa from acid and hostile luminal conditions.
  • Evolving ideas that may influence understand-ing of the physiologic consequences of emerging therapeutics, and procedures that target anatomy or function of the stomach are also reviewed.
  • [MeSH-major] Stomach / anatomy & histology. Stomach / physiology

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  • (PMID = 16139026.001).
  • [ISSN] 0039-6109
  • [Journal-full-title] The Surgical clinics of North America
  • [ISO-abbreviation] Surg. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 46
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69. Tsukamoto T, Mizoshita T, Tatematsu M: Animal models of stomach carcinogenesis. Toxicol Pathol; 2007 Aug;35(5):636-48
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Animal models of stomach carcinogenesis.
  • Although incidences of stomach cancer have decreased over the past several decades, the disease remains an important public health problem.
  • Helicobacter pylori(H. pylori) is one of the most important factors for human stomach disorders, including neoplasia, and the H. pylori-infected and carcinogen-treated Mongolian gerbil (MG) has proven very useful for analyses of underlying processes.
  • The findings with this model support the hypothesis that intestinal metaplasia is important not as a precancerous lesion but rather as a paracancerous condition and that intestinalization of stomach cancer progresses with chronic inflammation.
  • Furthermore, dose-dependent enhancing effects of salt on stomach carcinogenesis could be demonstrated in MGs treated with MNU and H. pylori modifying surface mucous gel layer. H. pylori itself only causes chronic inflammation and acts as a promoter of stomach carcinogenesis in experimental models.
  • Based on the precise pathological diagnosis of stomach lesions such as noncancerous heterotopic proliferative glands (HPG) and adenocarcinomas, a basis for understanding mechanisms of carcinogenesis has been established on which chemoprevention can be modeled.
  • [MeSH-major] Disease Models, Animal. Stomach Neoplasms / etiology
  • [MeSH-minor] Animals. Cyclooxygenase 2 / physiology. Helicobacter Infections / complications. Helicobacter pylori. Homeodomain Proteins / physiology. Humans. Metaplasia. Precancerous Conditions / pathology. Sodium Chloride, Dietary / adverse effects. Trans-Activators / physiology. Tumor Suppressor Protein p53 / physiology

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  • (PMID = 17654405.001).
  • [ISSN] 0192-6233
  • [Journal-full-title] Toxicologic pathology
  • [ISO-abbreviation] Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / Homeodomain Proteins; 0 / Sodium Chloride, Dietary; 0 / Trans-Activators; 0 / Tumor Suppressor Protein p53; 0 / pancreatic and duodenal homeobox 1 protein; EC 1.14.99.1 / Cyclooxygenase 2
  • [Number-of-references] 133
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70. Kuzin NM, Vetshev PS, Maĭorova IuB: [Resection of the stomach with Roux anastomosis]. Khirurgiia (Mosk); 2006;(3):4-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Resection of the stomach with Roux anastomosis].
  • Results of surgical treatment of patients with gastric ulcer and cancer of the stomach using resection of the stomach with Roux technique were analyzed.
  • Acid-producing and evacuatory functions of the stomach were assessed in different periods after surgery.
  • Dynamic scintigraphy provided evaluation of indices of duodenogastric reflux and state of gastric mucous barrier after various types of surgeries.
  • It is concluded that Roux resection of the stomach is not inferior to Bilrot-I resection by functional results, but it has advantages by quality life and rate of operated stomach diseases compared with Bilrot-I and Bilrot-II techniques.
  • [MeSH-major] Duodenum / surgery. Gastrectomy / methods. Stomach / surgery. Stomach Neoplasms / surgery. Stomach Ulcer / surgery

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  • (PMID = 16710233.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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71. Shimoda M, Okada Y, Hayashi Y, Hatano S, Kawakubo H, Omori T, Ishii S, Sugiura H: Primary invasive micropapillary carcinoma of the stomach. Pathol Int; 2008 Aug;58(8):513-7
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  • [Title] Primary invasive micropapillary carcinoma of the stomach.
  • Reported herein is the case of a 74-year-old man with an unusual gastric carcinoma that developed at the lesser curvature of the stomach.
  • The tumor consisted of small clusters of carcinoma cells surrounded by clear spaces, with histopathology similar to invasive micropapillary carcinoma (IMPC) of the breast.
  • Although IMPC has been reported in breast, urinary bladder, ureter, lung, salivary gland and colon, to the best of the authors' knowledge this is the first report of IMPC arising in the stomach.
  • Presented here are the clinicopathological features of primary IMPC of the stomach.
  • [MeSH-major] Carcinoma, Papillary / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Cadherins / analysis. Disease-Free Survival. Down-Regulation. Humans. Lymph Nodes / pathology. Lymph Nodes / surgery. Male. Neoplasm Invasiveness

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  • (PMID = 18705772.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cadherins
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72. Woodfield CA, Levine MS: The postoperative stomach. Eur J Radiol; 2005 Mar;53(3):341-52
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  • [Title] The postoperative stomach.
  • Gastric surgery may be performed for the treatment of a variety of benign and malignant diseases of the upper gastrointestinal tract, including peptic ulcers and gastric carcinoma.
  • Barium studies may also be obtained to evaluate for anastomotic strictures or ulcers, bile reflux gastritis, recurrent tumor, or other chronic complications during the late postoperative period.
  • Cross-sectional imaging studies such as CT are also helpful for detecting abscesses or other postoperative collections, recurrent or metastatic tumor, or less common complications such as afferent loop syndrome or gastrojejunal intussusception.
  • It is important for radiologists to be familiar not only with the radiographic findings associated with these various abnormalities but also with the normal appearances of the postoperative stomach on radiographic examinations, so that such appearances are not mistaken for pseudoleaks or other postoperative complications.
  • The purpose of this article is to describe the normal postsurgical anatomy after the most commonly performed operations (including partial gastrectomy, esophagogastrectomy and gastric pull-through, and total gastrectomy and esophagojejunostomy) and to review the acute and chronic complications, normal postoperative findings, and major abnormalities detected on radiographic examinations in these patients.
  • [MeSH-major] Postoperative Complications / radiography. Stomach Diseases / radiography. Stomach Diseases / surgery

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  • (PMID = 15741008.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
  • [Number-of-references] 56
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73. Novitskaia TA, Chuprov IN, Bratanchuk SIu, Zhelbunova EA: [Malignant stromal tumor of the stomach]. Arkh Patol; 2006 Mar-Apr;68(2):44-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant stromal tumor of the stomach].
  • Gastric tumor in a male of 67 is reported.
  • Immunohistochemically and morphologically the tumor is classified as a stromal stomach neoplasm.
  • [MeSH-major] Gastric Mucosa / pathology. Gastrointestinal Stromal Tumors / pathology. Stomach Neoplasms / pathology

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  • (PMID = 16752510.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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74. Gockel I, Heintz A, Trinh TT, Domeyer M, Dahmen A, Junginger T: Laparoscopic anterior semifundoplication in patients with intrathoracic stomach. Am Surg; 2008 Jan;74(1):15-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic anterior semifundoplication in patients with intrathoracic stomach.
  • The laparoscopic management of the intrathoracic stomach is still controversial.
  • The aim of our study was to evaluate the results of laparoscopic anterior semifundoplication in patients with intrathoracic stomach.
  • Enrolled in this study are 19 patients (67.1 years of age; range, 37.5-83.7 years) with intrathoracic stomach undergoing laparoscopic anterior semifundoplication and a minimal follow up of 5 months postoperatively.
  • Including criterion was a minimum percentage of herniated intrathoracic stomach of 33 per cent.
  • The median percentage of herniated stomach in the chest was 87.5 per cent (range, 33-100%).
  • Seven patients revealed organo-axial volvulus of the stomach.
  • Although laparoscopic anterior semifundoplication yields satisfactory symptomatic results in patients with intrathoracic stomach, the incidence of failures and anatomical recurrences is higher than expected from subjective data.
  • Prospective, randomized long-term studies are essential to gain further information about the "ideal" type of laparoscopic repair in large hiatal hernia with intrathoracic stomach.

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  • (PMID = 18274422.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Kong F, Singh RP: Disintegration of solid foods in human stomach. J Food Sci; 2008 Jun;73(5):R67-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Disintegration of solid foods in human stomach.
  • Knowledge of the disintegration of solid foods in human stomach is essential to assess the bioavailability of nutrients in the gastrointestinal (GI) tract.
  • A comprehensive review of food gastric digestion, focusing on disintegration of solid foods, is presented.
  • Stomach physiology is briefly introduced, including composition and rheological properties of gastric contents, stomach wall motility in fed/fasted states, and hydrodynamic and mechanical forces that act on the ingested food.
  • Stomach emptying rate, which controls the rate of absorption of nutrients, is highly related to the disintegration of foods.
  • Future research in this area is identified to increase our fundamental understanding of the food digestion process in the stomach as related to the food composition, material properties such as texture and microstructure, and chemical characteristics.
  • [MeSH-major] Digestion / physiology. Gastric Emptying / physiology. Stomach / metabolism

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  • (PMID = 18577009.001).
  • [ISSN] 1750-3841
  • [Journal-full-title] Journal of food science
  • [ISO-abbreviation] J. Food Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 137
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76. Mortensen MB, Fenger C: [Polyps in the stomach and duodenum]. Ugeskr Laeger; 2008 Jan 7;170(1):25-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Polyps in the stomach and duodenum].
  • The most common types in the stomach are fundic gland polyps, followed by hyperplastic polyps and adenomas.
  • Gastric metaplasia, adenomas and inflammatory polyps are the most common polyps in the duodenum.
  • [MeSH-major] Duodenal Diseases / pathology. Intestinal Polyps / pathology. Polyps / pathology. Stomach Diseases / pathology
  • [MeSH-minor] Adenoma / pathology. Adenoma / therapy. Adult. Duodenal Neoplasms / pathology. Duodenal Neoplasms / therapy. Duodenoscopy. Gastroscopy. Humans. Hyperplasia

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  • (PMID = 18208710.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 35
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77. Kutateladze M, Asatiani A: [Mechanosensoric homeostatic function of the stomach]. Georgian Med News; 2005 May;(122):69-72

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Mechanosensoric homeostatic function of the stomach].
  • Using original experimental method (partial, different extent emptying of stomach from contents in various parts of time after satiety condition--denying the food intake) the mechanosensoric, homeostatic function of the stomach was revealed while performing the chronic experiments on adult male dogs, while on puppies the ageing peculiarities of its formation was shown.
  • On polyfistuled (stomach, proximal and distal parts of duodenum) adult dogs, it was demonstrated that duodenum participates in maintenance and formation of satiety only while complex irritation by chime of the interoreceptors of gastrointestinal tract in natural succession of digestion takes place together with the sensoric processes in stomach.
  • [MeSH-major] Eating / psychology. Satiety Response / physiology. Stomach / physiology
  • [MeSH-minor] Animals. Dogs. Duodenum / physiology. Gastric Emptying. Gastrointestinal Motility. Homeostasis. Hunger / physiology. Male

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  • (PMID = 15988089.001).
  • [ISSN] 1512-0112
  • [Journal-full-title] Georgian medical news
  • [ISO-abbreviation] Georgian Med News
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Georgia (Republic)
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78. Gilja OH: Ultrasound of the stomach--the EUROSON lecture 2006. Ultraschall Med; 2007 Feb;28(1):32-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasound of the stomach--the EUROSON lecture 2006.
  • The stomach is a fascinating organ.
  • The aim of this paper is to show how transabdominal ultrasonography can disclose the structural and functional abnormalities of the stomach.
  • Ultrasound of the stomach was initially performed to detect and investigate organic diseases of the gastric wall.
  • Subsequently, different methods were developed to study functional aspects of gastric pathology.
  • Ultrasound can be used to evaluate antral contractility, gastric emptying, transpyloric flow, gastric configuration, intragastric distribution of meals, gastric accommodation and strain measurement of the gastric wall.
  • Advanced methods for 3D ultrasound imaging and tissue Doppler (Strain Rate Imaging) have also been developed to study diseases of the stomach.
  • Ultrasonography still has a great potential as a clinical method, and some day our patients may receive both diagnosis and treatment in the same session.
  • [MeSH-major] Stomach / ultrasonography
  • [MeSH-minor] Eating. Gastric Emptying. Humans. Muscle Contraction. Muscle, Smooth / physiology

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  • (PMID = 17304411.001).
  • [ISSN] 0172-4614
  • [Journal-full-title] Ultraschall in der Medizin (Stuttgart, Germany : 1980)
  • [ISO-abbreviation] Ultraschall Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 79
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79. Zhou JP, Yang ZL, Liu DC, Zhou JP: [Expression of galectin 3 and Sambucus nigra agglutinin and their clinicopathological significance in benign and malignant lesions of stomach]. Zhonghua Wei Chang Wai Ke Za Zhi; 2009 May;12(3):297-300
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of galectin 3 and Sambucus nigra agglutinin and their clinicopathological significance in benign and malignant lesions of stomach].
  • OBJECTIVE: To study the expressive levels of galectin-3(gal-3) and Sambucus nigra agglutinin(SNA) and their clinicopathological significance in the benign and malignant lesions of stomach.
  • METHODS: EnVision immunohistochemistry for assaying gal-3 expressive level and ABC cytochemistry for determining SNA expressive level were used in conventional paraffin-embedded sections from specimens of gastric cancer(n=49), peritumoral tissues(n=20), metastatic foci of lymph nodes(n=36), and different types of benign lesions(n=80).
  • RESULTS: The positive rates of gal-3 and SNA were significantly higher in gastric cancer tissues than those in peritumoral tissues and different types of benign lesions(P<0.05, P<0.01).
  • The positive cases of gal-3 and/or SNA in peritumoral tissues and benign lesions showed mild- to severe-atypical hyperplasia of mucous epithelial cells.
  • The positive rates of gal-3 and SNA were significantly lower in histologic grade II(, infiltrating depth T1,T2 and no-metastasis of regional lymph node than those in histologic grade III(,IIII(, infiltrating depth T3,T4 and metastasis of lymph node in gastric cancer(P<0.05).
  • The consistency was found between the expression of gal-3 and SNA in gastric cancer tissues(chi(2)=6.59,P<0.05).
  • CONCLUSIONS: The expressive levels of gal-3 and SNA may be important molecular markers of lectins for reflecting the carcinogenesis, progression and biological behaviors in gastric cancer.
  • [MeSH-major] Galectin 3 / metabolism. Plant Lectins / metabolism. Ribosome Inactivating Proteins / metabolism. Stomach Neoplasms / metabolism. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma / pathology. Adult. Aged. Female. Gastritis / pathology. Humans. Immunohistochemistry. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Polyps / pathology

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  • (PMID = 19434543.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Galectin 3; 0 / Plant Lectins; 0 / Sambucus nigra lectins; EC 3.2.2.22 / Ribosome Inactivating Proteins
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80. Lazebnik LB, Lychkova AÉ, Khomeriki SG: [Characteristics of neurohumoral regulation of stomach in aging]. Eksp Klin Gastroenterol; 2010;(12):73-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Characteristics of neurohumoral regulation of stomach in aging].
  • The neurohumoral regulation of the motor-secretory activity of the rabbit's and rat's stomach during aging was studied.
  • Adrenergic division's contribution in the regulation of gastric motility was lowered, cholinergic's--was slowly reduced and serotoninergic's was relatively increased.
  • Serotoninergic system enhances vagal stimulated uprise of gastric motor activity; serotoninergic system may partially compensate the age-dependent decline of the role of the cholinergic system in the regulation of gastric motility.
  • The stimulation of the vagus nerve induced serotonin secretion by EC-cells of the rat stomach.
  • [MeSH-major] Aging / physiology. Gastrointestinal Motility / physiology. Stomach / physiology. Vagus Nerve / physiology

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  • (PMID = 21560626.001).
  • [ISSN] 1682-8658
  • [Journal-full-title] Ėksperimental'nai︠a︡ i klinicheskai︠a︡ gastroėnterologii︠a︡ = Experimental & clinical gastroenterology
  • [ISO-abbreviation] Eksp Klin Gastroenterol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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81. Brenner H, Rothenbacher D, Arndt V: Epidemiology of stomach cancer. Methods Mol Biol; 2009;472:467-77
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology of stomach cancer.
  • Despite a major decline in incidence and mortality over several decades, stomach cancer is still the fourth most common cancer and the second most common cause of cancer death in the world.
  • The best established risk factors for stomach cancer are Helicobacter pylori infection, the by far strongest established risk factor for distal stomach cancer, and male sex, a family history of stomach cancer, and smoking.
  • While some factors related to diet and food preservation, such as high intake of salt-preserved foods and dietary nitrite or low intake of fruit and vegetables, are likely to increase the risk of stomach cancer, the quantitative impact of many dietary factors remains uncertain, partly due to limitations of exposure assessment and control for confounding factors.
  • Future epidemiologic research should pay particular attention to differentiation of stomach cancer epidemiology by subsite, and to exploration of potential interactions between H. pylori infection, genetic, and environmental factors.
  • [MeSH-major] Stomach Neoplasms / epidemiology

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  • (PMID = 19107449.001).
  • [ISSN] 1064-3745
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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82. Fedorov VD: [Extirpation of stomach without esophagoenteroanastomosis at recurrent profuse gastric bleedings]. Khirurgiia (Mosk); 2008;(3):4-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Extirpation of stomach without esophagoenteroanastomosis at recurrent profuse gastric bleedings].
  • Five cases of extirpation of stomach stump are analyzed.
  • These operations have been performed due to recurrent bleeding after long conservative treatment, endoscopic and surgical procedures (gastrotomy with suturing of erosions and ulcers, resection and re-resection of stomach) at the patients with severe anemia and hypoproteinemia.
  • [MeSH-major] Esophagus / surgery. Gastrointestinal Hemorrhage / surgery. Stomach / surgery

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  • (PMID = 18427523.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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83. Michiels A, Hubens G, Ruppert M, Balliu L, Vaneerdeweg W: Giant liposarcoma of the stomach involving the mediastinum. Acta Chir Belg; 2007 Jul-Aug;107(4):468-71
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant liposarcoma of the stomach involving the mediastinum.
  • A case of a liposarcoma of the stomach in a 27-year old woman is described.
  • MRI showed a giant tumour of the stomach wall, invading the surrounding organs, as well as the mediastinal region.
  • After surgical 'en-bloc' resection of the tumour, histopathologic examination yielded a diagnosis of pleiomorphic liposarcoma.
  • Nine months after surgery, she represented with a relapse of the tumour that had become inoperable.
  • Although liposarcoma is a very common soft tissue sarcoma, it is rarely seen in the stomach.
  • [MeSH-major] Liposarcoma / pathology. Mediastinum / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 17966553.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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84. Nyeng P, Norgaard GA, Kobberup S, Jensen J: FGF10 signaling controls stomach morphogenesis. Dev Biol; 2007 Mar 1;303(1):295-310
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] FGF10 signaling controls stomach morphogenesis.
  • Here we find that FGF10 signaling controls stomach progenitor maintenance, morphogenesis and cellular differentiation.
  • Through a characterization of the initiation of terminal differentiation of the three major gastric regions in the mouse, forestomach, corpus and antrum, we first describe the existence of a "secondary transition" event occurring in mouse stomach between E15.5 and E16.5.
  • This includes the formation of terminally differentiated squamous cells, parietal, chief and gastric endocrine cells from a pre-patterned gastric progenitor epithelium.
  • Expression analysis of both FGF and Notch signaling components suggested a role of these networks in such progenitors, which was tested through ectopically expressing FGF10 in the developing posterior stomach.
  • These data provide evidence that gastric gland specification and progenitor cell maintenance is controlled by FGF10.
  • These effects were paralleled by changes in Hes1, Shh and Wnt6 expression, suggesting that FGF10 acts in concert with multiple morphogenetic signaling systems during gastric development.

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  • (PMID = 17196193.001).
  • [ISSN] 0012-1606
  • [Journal-full-title] Developmental biology
  • [ISO-abbreviation] Dev. Biol.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK057516; United States / NIDDK NIH HHS / DK / R01 DK070636-01A1; United States / NIDDK NIH HHS / DK / R01 DK070636; United States / NIDDK NIH HHS / DK / R01 DK070636-02; United States / NIDDK NIH HHS / DK / R01 DK 070636; United States / NIDDK NIH HHS / DK / P30 DK 57516
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fgf10 protein, mouse; 0 / Fibroblast Growth Factor 10; 0 / Hedgehog Proteins; 0 / Proto-Oncogene Proteins; 0 / Shh protein, mouse; 0 / Wnt Proteins; 0 / Wnt6 protein, mouse
  • [Other-IDs] NLM/ NIHMS19042; NLM/ PMC1864952
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85. Kazymov IL, Mekhdiev AG, Kurbanov FS: [Bleedings from ulcers after resection of stomach and vagotomy]. Khirurgiia (Mosk); 2008;(2):37-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bleedings from ulcers after resection of stomach and vagotomy].
  • Resection of stomach was performed in 69 (42.6%) of them, vagotomy--in 93 (57.4%).
  • Episodes of bleeding were revealed in anamnesis at 56 (81.2%) patients with peptic ulcers after stomach resection, and at 15 (16.1%)--with ulcers after vagotomy.
  • Repeated resection of gastric stump with vagotomy is indicated in great penetrating ulcers.
  • Resection of stomach is the operation of choice in majority cases of recurrent ulcers after primary vagotomy.
  • [MeSH-major] Stomach Ulcer / surgery. Vagotomy / methods

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  • (PMID = 18427491.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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86. Velanovich V, Mohlberg N: The split-stomach fundoplication after esophagogastrectomy. J Gastrointest Surg; 2006 Feb;10(2):178-83, discussion184-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The split-stomach fundoplication after esophagogastrectomy.
  • We describe here a modification of an intrathoracic esophagogastrostomy using the gastric fundus to address these issues.
  • This wrap is secured to the esophagus and to the stomach.
  • All patients undergoing the split-stomach fundoplication were compared with all patients undergoing standard esophagogastrectomies.
  • Twenty-six patients underwent the split-stomach fundoplication (wrap group), compared to 54 patients undergoing standard resection (no wrap group).
  • The addition of the split-stomach fundoplication to esophagogastrectomy may decrease the incidence of anastomotic leak and postoperative refluxlike symptoms.
  • [MeSH-major] Esophagectomy / methods. Fundoplication / methods. Gastrectomy / methods. Stomach / surgery
  • [MeSH-minor] Aged. Anastomosis, Surgical / adverse effects. Barrett Esophagus / surgery. Cause of Death. Dilatation. Esophageal Stenosis / etiology. Esophageal Stenosis / therapy. Esophagoscopy. Female. Follow-Up Studies. Gastroesophageal Reflux / etiology. Gastroscopy. Humans. Male. Postoperative Complications. Quality of Life. Stomach Neoplasms / surgery. Surgical Stapling. Suture Techniques. Treatment Outcome

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  • (PMID = 16455448.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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87. Mun SA, Larin SA, Glushkov AN, Schastlivtsev EL, Brailovskiĭ VV, Chukhrov IuS, Baĭbulatov RA: [The morbidity of stomach cancer among the workers of key industries of the Kuznetsk Basin (Kuzbas)]. Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med; 2008 May-Jun;(3):18-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The morbidity of stomach cancer among the workers of key industries of the Kuznetsk Basin (Kuzbas)].
  • The data research of the retrospective analysis of the morbidity of stomach cancer in the Kirov oblast (1990-2005) is presented.
  • The forecasting of morbidity rate of stomach cancer is estimated up to 2013 considering the factual indicators of volume of output in the key industries of Kuzbas.

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  • (PMID = 18807870.001).
  • [ISSN] 0869-866X
  • [Journal-full-title] Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny
  • [ISO-abbreviation] Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
  • [Language] RUS
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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88. Fukuda K, Yasugi S: The molecular mechanisms of stomach development in vertebrates. Dev Growth Differ; 2005 Aug;47(6):375-82

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The molecular mechanisms of stomach development in vertebrates.
  • In this review, we introduce a series of works to elucidate the molecular mechanisms of the epithelial-mesenchymal interaction of stomach development in mainly the chicken embryo.
  • We also describe some molecular studies in mouse stomach development.
  • [MeSH-major] Stomach / embryology. Vertebrates / embryology

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  • (PMID = 16109035.001).
  • [ISSN] 0012-1592
  • [Journal-full-title] Development, growth & differentiation
  • [ISO-abbreviation] Dev. Growth Differ.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 69
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89. Portnoĭ LM, Viatchanin OV: [The modern role of stomach cancer radiodiagnostics]. Vestn Ross Akad Med Nauk; 2005;(6):12-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The modern role of stomach cancer radiodiagnostics].
  • The authors' main purpose was to assess the role of stomach cancer radiodiagnostics, considering the changes in the morphology of the disease within the last decades of the 20th century.
  • The results of radiodiagnostic and morphological study of 1258 cases of verified stomach cancer were compared.
  • This methodical approach allowed correction of radiodiagnostic methods and stomach cancer semiotics, directed towards detection of endophytic tumors.
  • The radiologic examination included conventional radiologic imaging, ultrasonography, computed tomography, and magnetic resonance imaging of the stomach.
  • The morphologic examination included a method of studying endophytic stomach cancer, specially designed for this research.
  • According to the authors of the article, the prevalence of diffuse and mixed stomach cancer has increased substantially within the last 34 years; the incidence of the stomach upper part involvement has increased 2.4 times.
  • The modem radiodiagnostics and semiotics of stomach cancer are based on the principles of endophytic tumor detection.
  • The authors conclude that modern radiodiagnostics and endoscopy are two main methods of stomach cancer diagnostics.

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  • (PMID = 16022106.001).
  • [ISSN] 0869-6047
  • [Journal-full-title] Vestnik Rossiiskoi akademii meditsinskikh nauk
  • [ISO-abbreviation] Vestn. Akad. Med. Nauk SSSR
  • [Language] RUS
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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90. Baron JH, Watson F, Sonnenberg A: Three centuries of stomach symptoms in Scotland. Aliment Pharmacol Ther; 2006 Sep 1;24(5):821-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Three centuries of stomach symptoms in Scotland.
  • BACKGROUND: Stomach pain and discomfort have been reported since antiquity.
  • AIM: To follow the time trends since the 18th century of dyspepsia, gastric ulcer, duodenal ulcer, and benign oesophageal disease to test when dyspepsia started to become a major clinical problem.
  • Such dyspepsia persisted after gastric and duodenal ulcers appeared in the late 19th century and then declined again in the late 20th century.
  • Non-ulcer dyspepsia has remained the commonest diagnosis made after endoscopy for stomach pain in the beginning of the 21st century.
  • CONCLUSION: The current commonest diagnosis of stomach pain, dyspepsia dates from the mid-18th century.
  • [MeSH-minor] Ambulatory Care / history. Duodenal Ulcer / epidemiology. Duodenal Ulcer / history. Dyspepsia / epidemiology. Dyspepsia / history. Esophageal Diseases / epidemiology. Esophageal Diseases / history. Female. History, 18th Century. History, 19th Century. History, 20th Century. Hospitalization. Humans. Male. Scotland / epidemiology. Stomach Ulcer / epidemiology. Stomach Ulcer / history

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  • (PMID = 16918886.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] England
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91. Ohtsuka H, Kanzaki M, Imamura K, Kikkawa T, Obara T, Ishizawa M, Takahara Y, Matsumoto J: [Adult Bochdalek hernia with volvulus of the stomach]. Kyobu Geka; 2008 Sep;61(10):877-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adult Bochdalek hernia with volvulus of the stomach].
  • We report a rare case of Bochdalek hernia, congenital posterolateral diaphragmatic hernia with volvulus of the stomach, in an adult A 74-year-old man was admitted to our hospital complaining of sudden abdominal pain and vomiting.
  • Upper gastrointestinal series revealed volvulus of the stomach in which the pylorus was displaced to the left.
  • [MeSH-major] Hernia, Diaphragmatic / complications. Hernia, Diaphragmatic / surgery. Stomach Volvulus / complications. Stomach Volvulus / surgery
  • [MeSH-minor] Aged. Diaphragm / surgery. Humans. Laparoscopy. Male. Stomach / surgery. Thoracoscopy. Thoracotomy. Treatment Outcome

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  • (PMID = 18788379.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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92. Prenzel KL, Schäfer E, Stippel D, Beckurts KT, Hölscher AH: Multiple giant leiomyomas of the esophagus and stomach. Dis Esophagus; 2006;19(6):504-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple giant leiomyomas of the esophagus and stomach.
  • Leiomyomas are rare esophageal disorders, although among the benign esophageal neoplasms, they are the most common.
  • On endoscopy multiple nodules covered with intact mucosa were present, the largest tumor arising from the gastro-esophageal border infiltrating the cardia.
  • Barium swallow demonstrated narrowing of the middle and lower esophagus with the upper third of the stomach filled by the tumor.
  • Thorax and abdominal CT scans revealed infiltration of almost the total aboral esophagus by the tumor with compression of left and right bronchi.
  • The infiltration reached the whole lesser curvature of the stomach.
  • Due to the extended tumor growth with infiltration of the upper third of the stomach, a total esophago-gastrectomy with reconstruction by colon interposition was performed.
  • On histopathological examination multiple esophageal leiomyomas with infiltration of the proximal third of the stomach was shown.
  • Immunohistochemically the tumor stained positive for desmin and sm-actin and negative for CD34 and c-kit.
  • In young patients with diffuse multinodular infiltration by encapsulated tumors, esophageal leiomyomatosis should be considered.
  • If the proximal third of the stomach is infiltrated by the tumor an extended resection is necessary.

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  • (PMID = 17069596.001).
  • [ISSN] 1120-8694
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / COL4A5 protein, human; 0 / Collagen Type IV
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93. Marie I, Ducrotte P, Antonietti M, Herve S, Levesque H: Watermelon stomach in systemic sclerosis: its incidence and management. Aliment Pharmacol Ther; 2008 Aug 15;28(4):412-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Watermelon stomach in systemic sclerosis: its incidence and management.
  • BACKGROUND: To date, there are no large endoscopic studies in systemic sclerosis (SSc), and both prevalence and characteristics of watermelon stomach in SSc have not been determined.
  • AIMS: To determine the prevalence, clinical presentation, endoscopic appearance, therapy success and long-term outcome in SSc patients with watermelon stomach and make predictions about which SSc patients are at risk for watermelon stomach.
  • Data were collected as regards patients' characteristics, time of watermelon stomach onset, features, therapy and outcome of watermelon stomach.
  • RESULTS: Fifteen SSc patients (5.7%) exhibited watermelon stomach.
  • SSc onset preceded watermelon stomach manifestations in 13 patients (86.7%).
  • Gastroscopy disclosed typical 'watermelon stomach' characterized by prominent, erythematous stripes, radiating in a spoke-like fashion from the antrum to the pylorus.
  • All patients received conservative therapy; because of deterioration of watermelon stomach, eight patients (53.3%) underwent endoscopic procedures.
  • During follow-up, five patients (33.3%) exhibited recurrences of watermelon stomach.
  • CONCLUSIONS: Our series indicates that watermelon stomach should be considered when unexplained iron-deficiency anaemia occurs in SSc patients.
  • Moreover, because watermelon stomach may be the first manifestation of SSc, patients with unexplained watermelon stomach should systematically undergo physical examination and autoantibody testing to detect the underlying SSc.
  • [MeSH-major] Anemia, Iron-Deficiency / etiology. Gastric Antral Vascular Ectasia / diagnosis. Gastrointestinal Hemorrhage / complications. Scleroderma, Systemic / complications


94. Tsai LH: Function of GABAergic and glutamatergic neurons in the stomach. J Biomed Sci; 2005;12(2):255-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Function of GABAergic and glutamatergic neurons in the stomach.
  • Gamma-aminobutyric acid (GABA) and L-glutamic acid (L-Glu) are transmitters of GABAergic and glutamatergic neurons in the enteric interneurons, targeting excitatory or inhibitory GABA receptors or glutamate receptors that modulate gastric motility and mucosal function.
  • GABAergic and glutamatergic neuron immunoreactivity have been found in cholinergic enteric neurons in the stomach.
  • [MeSH-major] Glutamine / metabolism. Neurons / metabolism. Receptors, GABA / metabolism. Stomach / metabolism
  • [MeSH-minor] Animals. Central Nervous System / metabolism. Feeding Behavior. Gastric Acid / metabolism. Gastric Mucosa / metabolism. Humans. Mucous Membrane / metabolism. Muscle Contraction. Muscle, Smooth / cytology. Receptors, Cholinergic / metabolism. Receptors, Glutamate / metabolism. Signal Transduction. Ulcer

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  • (PMID = 15917994.001).
  • [ISSN] 1021-7770
  • [Journal-full-title] Journal of biomedical science
  • [ISO-abbreviation] J. Biomed. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Receptors, Cholinergic; 0 / Receptors, GABA; 0 / Receptors, Glutamate; 0RH81L854J / Glutamine
  • [Number-of-references] 83
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95. Isik A, Alimoglu O, Okan I, Bas G, Turgut H, Sahin M: Dieulafoy lesion in the stomach. Case Rep Gastroenterol; 2008 Sep;2(3):469-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dieulafoy lesion in the stomach.
  • There are many methods for diagnosis and treatment.
  • In this case, a patient with a long-time undiagnosed stomach Dieulafoy lesion had a surgical resection.

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  • [Cites] Surg Endosc. 2002 Jan;16(1):219 [11961659.001]
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  • (PMID = 21897801.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3166813
  • [Keywords] NOTNLM ; Dieulafoy lesion / Gastrointestinal system bleeding
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96. Iwamuro M, Tanaka S, Bessho A, Takahashi H, Ohta T, Takada R, Murakami I: Two cases of primary small cell carcinoma of the stomach. Acta Med Okayama; 2009 Oct;63(5):293-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two cases of primary small cell carcinoma of the stomach.
  • We report 2 cases of small cell carcinoma (SmCC) of the stomach with distant metastasis that were treated with the same chemotherapeutic regimens as used to treat small cell lung cancer.
  • Although the mean survival of patients with SmCC of the stomach is reported to be only 7 months, our patients survived for 15 and 14 months, respectively.
  • In our experience, these chemotherapeutic regimens might provide a survival benefit for patients with SmCC of the stomach, although they demonstrated no remarkable antitumor effects.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Small Cell / drug therapy. Stomach Neoplasms / drug therapy

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  • (PMID = 19893606.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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97. Currò D, Ipavec V, Preziosi P: Neurotransmitters of the non-adrenergic non-cholinergic relaxation of proximal stomach. Eur Rev Med Pharmacol Sci; 2008 Aug;12 Suppl 1:53-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurotransmitters of the non-adrenergic non-cholinergic relaxation of proximal stomach.
  • The proximal third of the stomach (fundus plus oral corpus) relaxes during swallowing so that it can hold large amounts of food with limited increases in intraluminal pressure.
  • When the food bolus reaches the stomach, gastric relaxation is maintained by another reflex starting from mechanoreceptors in the gastric wall.
  • This second mechanism has been named "adaptive relaxation" or "gastric accommodation" and involves both intramural and vagal reflex pathways, whose inhibitory neurons are always intramural.
  • This review will deal mainly with the physiological characteristics and pharmacological features of the NANC relaxation of the proximal stomach and the evidences favoring or excluding a role as inhibitory neurotransmitters of ATP, NO and VIP in different species.
  • [MeSH-major] Autonomic Nervous System / physiology. Neurotransmitter Agents / physiology. Stomach / innervation. Stomach / physiology

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  • (PMID = 18924444.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Neurotransmitter Agents; 31C4KY9ESH / Nitric Oxide; 37221-79-7 / Vasoactive Intestinal Peptide; 8L70Q75FXE / Adenosine Triphosphate
  • [Number-of-references] 97
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98. Liao D, Zhao J, Gregersen H: Regional surface geometry of the rat stomach based on three-dimensional curvature analysis. Phys Med Biol; 2005 Jan 21;50(2):231-46

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regional surface geometry of the rat stomach based on three-dimensional curvature analysis.
  • A better understanding of gastric accommodation and gastric perception requires knowledge of regional gastric geometry and local gastric tension throughout the stomach.
  • An analytic method based on medical imaging data was developed in this study to describe the three-dimensional (3D) rat stomach geometry and tension distribution.
  • The surface principal radii of curvatures were simulated and the surface tension was calculated in the glandular and non-glandular region of the stomach at pressures from 0 Pa to 800 Pa.
  • The radii of curvature and tension distribution in the stomach were non-homogeneous.
  • The radii of curvature in the glandular stomach were larger than those in the non-glandular region at pressures less than 100 Pa (P < 0.001).
  • When the pressure increased to more than 200 Pa, the radii of curvature in the non-glandular stomach was larger than in the glandular stomach (P < 0.05).
  • The curvature and tension distribution mapping using medical imaging technology and 3D models can be used to characterize and distinguish the physical behaviour in separate regions of the stomach.
  • [MeSH-major] Anatomy, Cross-Sectional / methods. Image Interpretation, Computer-Assisted / methods. Imaging, Three-Dimensional / methods. Models, Biological. Stomach / physiology. Stomach / ultrasonography

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  • (PMID = 15742941.001).
  • [ISSN] 0031-9155
  • [Journal-full-title] Physics in medicine and biology
  • [ISO-abbreviation] Phys Med Biol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] England
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99. Cetin E, Malas MA, Albay S, Cankara N: The development of stomach during the fetal period. Surg Radiol Anat; 2006 Oct;28(5):438-46

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The development of stomach during the fetal period.
  • The objective of this study was to explore the fetal development of the stomach, its morphology and relationship with neighboring structures.
  • Width and height of the stomach, lengths of the greater and lesser curvatures, the angle between horizontal and vertical axes of the stomach and types of stomach were established.
  • During the fetal life stomach was most commonly located above the transverse axis passing through the umbilicus, in left and right hypochondrium (81%).
  • There were significant differences among trimester groups with respect to the localization of the stomach in the quadrants (P < 0.001).
  • After the second trimester, the height of the stomach increased more than the width of the stomach and anterior abdominal height.
  • The angle of stomach decreased from 100 degrees to 50 degrees throughout the fetal period.
  • During the fetal period, wide angles stomach was more common in the first(f) and second trimesters while acute-angled stomach was more common in the third trimester and term fetuses.
  • Diagnosis and treatment of fetal anomalies and pathologies of the stomach requires knowledge of fetal anatomy of the stomach.
  • Data acquired in this study are believed to contribute to the studies of obstetrics, perinatology, forensic medicine and fetal pathology on fetal development of the stomach, and diagnosis and treatment of its anomalies, pathologies, and variations.
  • [MeSH-major] Stomach / embryology

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  • (PMID = 16906359.001).
  • [ISSN] 0930-1038
  • [Journal-full-title] Surgical and radiologic anatomy : SRA
  • [ISO-abbreviation] Surg Radiol Anat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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100. Kuroda N, Oonishi K, Inoue K, Ohara M, Mizuno K, Lee GH: Lymphoepithelioma-like carcinoma of the stomach associated with adenosquamous carcinoma. Med Mol Morphol; 2010 Sep;43(3):170-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoepithelioma-like carcinoma of the stomach associated with adenosquamous carcinoma.
  • Lymphoepithelioma-like carcinoma and adenosquamous carcinoma of the stomach are relatively rare tumors.
  • To date, there are no reports on lymphoepithelioma-like carcinoma of the stomach associated with adenosquamous carcinoma.
  • We report herein the first case of such a tumor.
  • The gastric endoscopy revealed an ulcerative cancerous lesion of the upper portion.
  • Histological examination of the gastric tumor showed the coexistence of lymphoepithelioma-like carcinoma and adenosquamous carcinoma.
  • Finally, this is the first case of gastric lymphoepithelioma-like carcinoma associated with adenosquamous carcinoma, and clinicians and pathologists should recognize the presence of such a tumor.
  • [MeSH-major] Carcinoma, Adenosquamous / pathology. Lymphoma / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Male. RNA-Binding Proteins / analysis. Ribosomal Proteins / analysis

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  • (PMID = 20857266.001).
  • [ISSN] 1860-1499
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA-Binding Proteins; 0 / Ribosomal Proteins; 135844-68-7 / RPL22 protein, human
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