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1. Cardona DM, Knapik JA, Reith JD: Dedifferentiated parosteal osteosarcoma with giant cell tumor component. Skeletal Radiol; 2008 Apr;37(4):367-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dedifferentiated parosteal osteosarcoma is characterized histologically by the admixture of low-grade fibroblastic osteosarcoma and a high-grade component typically resembling conventional osteosarcoma or malignant fibrous histiocytoma.

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  • (PMID = 18256826.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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2. Latif MJ, Rahman GF, Connery CP: Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus. J Bronchology Interv Pulmonol; 2009 Jul;16(3):188-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus.
  • Sclerosing hemangioma is a rare pulmonary tumor that usually grows as a peripheral intraparenchymal lesion in the lungs.
  • Although some case series have described this rare tumor, endobronchial growth of sclerosing hemangioma is extremely rare, with only 3 reported cases in the literature to date.

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  • (PMID = 23168550.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Ho MM, Howard TJ, Lillemoe KD: Can pancreaticoduodenectomy be used to palliate selective metastatic malignancies? Case report of malignant fibrous histiocytoma. J Gastrointest Surg; 2005 Sep-Oct;9(7):934-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Can pancreaticoduodenectomy be used to palliate selective metastatic malignancies? Case report of malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / secondary. Palliative Care. Pancreaticoduodenectomy

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  • (PMID = 16137587.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Kakitsubata Y, Theodorou SJ, Theodorou DJ, Nabeshima K, Kakitsubata S, Friedman PJ: Myofibroblastic inflammatory tumor of the lung: CT findings with pathologic correlation. Comput Med Imaging Graph; 2007 Dec;31(8):607-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Variable degree of fibrous histiocytoma type was observed in all cases.

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  • (PMID = 17719202.001).
  • [ISSN] 0895-6111
  • [Journal-full-title] Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
  • [ISO-abbreviation] Comput Med Imaging Graph
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Lee MH, Kim NR, Ryu JA: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol; 2010 Oct;39(10):981-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Of 23 masses, there were 5 giant cell tumors of the tendon sheath, 4 schwannomas, 3 vascular leiomyomas, 2 benign fibrous histiocytomas, 2 dermatofibrosarcoma protuberans, 2 granular cell tumors, 1 dermatofibroma, 1 fibroma of the tendon sheath, 1 fibromatosis, 1 eccrine spiradenoma, and 1 granulation tissue.
  • Such cases are not common, and fibrous tumors are the most frequent.
  • [MeSH-major] Cysts / diagnostic imaging. Musculoskeletal Diseases / diagnostic imaging. Soft Tissue Neoplasms / diagnostic imaging. Ultrasonography, Doppler, Color / methods

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  • (PMID = 20186412.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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6. Hussein MR: Skin metastasis: a pathologist's perspective. J Cutan Pathol; 2010 Sep;37(9):e1-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin metastasis: a pathologist's perspective.
  • Skin metastasis is defined as the spread of malignant cells from a primary malignancy to the skin.
  • The tumor cells originate either from an internal malignancy or from a primary skin cancer.
  • Generally, skin metastases are encountered in 0.7-9% of all patients with cancer and as such the skin is an uncommon site of metastatic disease when compared to other organs.
  • There is usually a long-time lag between the diagnosis of the primary malignancy and the recognition of the skin metastases.
  • The regional distribution of the skin metastasis, although not always predictable, is related to the location of the primary malignancy and the mechanism of metastatic spread.
  • The relative frequency of skin metastasis correlates with the type of primary cancer, which occurs in each sex.
  • For instance, lung and breast carcinomas are the most common primaries that send skin metastasis in men and women, respectively.
  • Skin metastases usually appear as non-specific groups of discrete firm painless nodules that emerge rapidly without any explanation.
  • Some skin metastasis may mimic specific dermatological conditions such as cutaneous cyst, dermatofibroma, pyogenic granuloma, hemangioma, papular eruptions, herpes zoster eruptions, rapidly infiltrating plaques, alopecic patches, cellulitis and erysipelas.
  • Histologically, the skin metastases usually show features reminiscent of the primary malignancy, but with variable degrees of differentiation.
  • Molecularly, skin metastasis is an organized, non-random and organ-selective process orchestrated by interaction among several heterogeneous molecules, which are largely unknown.
  • Metastasis to the skin is often a pre-terminal event that heralds poor outcome.
  • [MeSH-major] Skin Neoplasms / secondary

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  • (PMID = 19922483.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
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7. Shi WM, Liao WQ, Wu ZW, Pandey P, Mei XY, Qin HH, Xu JH, Shen L: Recurrent cutaneous malignant fibrous histiocytoma. Eur J Dermatol; 2009 Mar-Apr;19(2):187-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent cutaneous malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 19264583.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] France
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8. Micantonio T, Fargnoli MC, Peris K: Giant dermatofibroma appearing during pregnancy. Acta Derm Venereol; 2006;86(1):86-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant dermatofibroma appearing during pregnancy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Skin Neoplasms / diagnosis


9. Asadi Amoli F, Sina AH, Kasai A, Ayan Z: A well-known lesion in an unusual location: infantile myofibroma of the eyelid: a case report and review of literature. Acta Med Iran; 2010 Nov-Dec;48(6):412-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It has a benign course in the solitary form and fatal in its multiple form.
  • A 4 month male infant referred to Farabi hospital -the referral center for eye diseases- with a 2 month history of a mass in his eyelid with gradual enlargement with no other complaints.
  • When confronting a spindle cell lesion with a nodular or multinodular growth pattern which appears biphasic due to alteration of light and dark staining areas, the surgical pathologist should think to the possibility of myofibroma.
  • Its pattern of growth and architecture rules out the other differential diagnoses like nodular fasciitis, fibrous histiocytoma, infantile fibromatosis, and peripheral primitive neuroectodermal tumor, mesenchymal chondrosarcoma, malignant hemangiopericytoma, juvenile fibrosarcoma and poorly differentiated synovial sarcoma.

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  • (PMID = 21287484.001).
  • [ISSN] 1735-9694
  • [Journal-full-title] Acta medica Iranica
  • [ISO-abbreviation] Acta Med Iran
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Iran
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10. Hong Y, Chen S, Zhang JM: [Bilateral diffusive benign fibrous histiocytoma in retrobulbar muscle cone: a case report]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2010 Sep;39(5):548-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bilateral diffusive benign fibrous histiocytoma in retrobulbar muscle cone: a case report].
  • [MeSH-major] Histiocytoma, Benign Fibrous. Orbital Neoplasms

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  • (PMID = 20936733.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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11. Rawal YB, Kalmar JR, Shumway B, Mallery SR: Presentation of an epithelioid cell histiocytoma on the ventral tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Jul;100(1):75-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Presentation of an epithelioid cell histiocytoma on the ventral tongue.
  • The epithelioid cell histiocytoma (ECH) is a polypoidal benign tumor of superficial connective tissue that is often diagnosed as a pyogenic granuloma.
  • Although dendritic subunits are distributed throughout most collagenous tissues inclusive of oral mucosa, to date, all reported cases of ECH have been cutaneous lesions.
  • Consistent with its benign course, the ECH is managed by local excision, and has an excellent prognosis.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Tongue Neoplasms / pathology

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  • (PMID = 15953920.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD31; 0 / Antigens, CD34; 68238-35-7 / Keratins; EC 2.3.2.13 / Factor XIIIa
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12. Gleason BC, Fletcher CD: Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol; 2008 Mar;32(3):354-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential.
  • Benign fibrous histiocytoma (FH) is one of the most common mesenchymal neoplasms of the skin.
  • Several histologic variants of cutaneous FH have been described, some of which also have distinct clinical features including a propensity for local recurrence.
  • Deep benign FH is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue.
  • Four cases were classified as atypical deep FH due to the presence of scattered markedly pleomorphic spindle cells within an otherwise histologically typical lesion.
  • In summary, deep FH has many histologic features in common with cutaneous cellular FH; however, it usually has a more diffusely storiform pattern than the latter, is well circumscribed, and may have striking hemangiopericytomalike vessels.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasm Metastasis / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 18300816.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin
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13. Kau HC, Yang CF, Liu IT, Kao SC, Hsu WM, Teng MM, Tsai CC: Benign fibrous histiocytoma associated with a frontoethmoidal mucopyocele and orbital abscess. Ophthal Plast Reconstr Surg; 2007 May-Jun;23(3):236-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign fibrous histiocytoma associated with a frontoethmoidal mucopyocele and orbital abscess.
  • Histopathologic examination proved it to be a benign fibrous histiocytoma.
  • Benign fibrous histiocytoma may occur in association with an orbital abscess secondary to mucocele.
  • [MeSH-major] Abscess / complications. Eye Infections, Bacterial / complications. Eyelid Neoplasms / etiology. Histiocytoma, Benign Fibrous / etiology. Mucocele / complications. Orbital Diseases / complications. Paranasal Sinus Diseases / complications. Pseudomonas Infections / complications

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  • (PMID = 17519668.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Takase K, Suzuki H, Matsuoka H: The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report. West Indian Med J; 2010 Jan;59(1):106-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report.
  • Malignant fibrous histiocytoma (MFH) is a type of highly malignant soft tissue sarcoma with a predilection for the extremities of adults.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Muscle, Skeletal / pathology. Muscle, Skeletal / surgery. Reconstructive Surgical Procedures / methods. Shoulder / surgery. Soft Tissue Neoplasms / surgery. Surgical Flaps

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  • (PMID = 20931927.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Jamaica
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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15. Nakai K, Yoneda K, Moriue J, Moriue T, Igawa K, Kubota Y: A case of multiple benign fibrous histiocytoma with indeterminate cells and eosinophils. J Eur Acad Dermatol Venereol; 2010 Oct;24(10):1236-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of multiple benign fibrous histiocytoma with indeterminate cells and eosinophils.
  • [MeSH-major] Eosinophils / pathology. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology

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  • (PMID = 20202056.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD1; 0 / CD1a antigen; 0 / S100 Proteins
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16. Tschoep K, Kohlmann A, Schlemmer M, Haferlach T, Issels RD: Gene expression profiling in sarcomas. Crit Rev Oncol Hematol; 2007 Aug;63(2):111-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sarcomas are a heterogeneous group of malignant mesenchymal tumors of difficult classification.
  • These markers give new insight into the pathogenesis of sarcomas, such as malignant fibrous histiocytoma [Lee YF, et al.
  • Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling.


17. Hoshi M, Matsumoto S, Manabe J, Tanizawa T, Shigemitsu T, Izawa N, Takeuchi K, Kawaguchi N: Malignant change secondary to fibrous dysplasia. Int J Clin Oncol; 2006 Jun;11(3):229-35
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  • [Title] Malignant change secondary to fibrous dysplasia.
  • BACKGROUND: Malignant change in fibrous dysplasia (FD) is very rare.
  • This study was carried out to establish some characteristic clinical information about this disorder.
  • METHODS: Four cases with a malignant change in FD out of 128 cases with FD were surgically treated and followed up for a median period of 61.3 months.
  • Histopathologically, two cases were osteosarcoma, one case was malignant fibrous histiocytoma (MFH), and one case was fibrosarcoma.
  • [MeSH-major] Bone Neoplasms / etiology. Bone Neoplasms / pathology. Fibrous Dysplasia of Bone / complications. Sarcoma / etiology. Sarcoma / pathology


18. Dhillon J, Amin MB, Selbs E, Turi GK, Paner GP, Reuter VE: Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change. Am J Surg Pathol; 2009 Jan;33(1):44-9
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  • Mucinous tubular and spindle cell carcinoma is a RCC subtype, which is defined as polymorphous histology wherein the spindled epithelial cell is an inherent carcinomatous component.
  • In addition to the classic mucinous tubular and spindle cell carcinoma morphology, both cases had a sarcomatoid component characterized by predominantly high-grade spindle cells, solid pleomorphic epithelioid cells, and malignant fibrous histiocytoma-like storiform patterns.

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  • (PMID = 18941398.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Capovilla M, Birembaut P, Cucherousset J, Ploton D, de Saint-Maur PP, Fléjou JF, Lesec G: Pleomorphic hyalinizing angiectatic tumor of soft parts: ultrastructural analysis of a case with original features. Ultrastruct Pathol; 2006 Jan-Feb;30(1):59-64
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  • [Title] Pleomorphic hyalinizing angiectatic tumor of soft parts: ultrastructural analysis of a case with original features.
  • Pleomorphic hyalinizing angiectatic tumor, a rare neoplasm of uncertain lineage resembling malignant fibrous histiocytoma and schwannoma, was first described in 1996 by M. E. F.
  • To date, less than 100 cases have been reported in the international literature.
  • All lesions are composed of sheets and fascicles of spindled and pleomorphic cells associated with clusters of thick-walled ectatic vessels surrounded by a perivascular hyaline material and inflammatory cells such as mast cells.
  • [MeSH-minor] Aged. Angiofibroma / diagnosis. Biomarkers, Tumor / metabolism. Blood Vessels / pathology. Diagnosis, Differential. Fibroma / diagnosis. Giant Cells / pathology. Histiocytoma, Malignant Fibrous / diagnosis. Humans. Hyalin / metabolism. Immunoenzyme Techniques. Male. Neurilemmoma / diagnosis

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  • (PMID = 16517471.001).
  • [ISSN] 1521-0758
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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20. Sakao Y, Tomimitsu S, Takeda Y, Natsuaki M, Itoh T: Malignant fibrous histiocytoma of the trachea. Jpn J Thorac Cardiovasc Surg; 2005 May;53(5):276-9
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  • [Title] Malignant fibrous histiocytoma of the trachea.
  • We experienced a rare case of malignant fibrous histiocytoma (MFH) arising in the trachea.
  • [MeSH-major] Histiocytoma, Benign Fibrous / surgery. Tracheal Neoplasms / surgery

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  • [ISSN] 1344-4964
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  • Histologic diagnoses were as follows: malignant fibrous histiocytoma in 6, liposarcoma in 3, malignant peripheral nerve sheath tumor in 3, Ewing/primitive neuroectodermal tumor (PNET) in 2, and miscellaneous in 10 patients.

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  • (PMID = 19467578.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbon Radioisotopes; 7440-44-0 / Carbon
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22. Goto T, Okuma T, Nakada I, Hozumi T, Kondo T: [Preoperative adjuvant therapy for primary malignant bone tumors]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1750-4
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  • Nowadays, in highgrade bone sarcomas, especially in osteosarcoma, Ewing.s sarcoma and malignant fibrous histiocytoma of bone, adjuvant chemotherapy including neoadjuvant or preoperative chemotherapy is usually performed.

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  • (PMID = 18030009.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; UM20QQM95Y / Ifosfamide; VAC protocol; VACA protocol; VAIA protocol
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23. Rhomberg W: The radiation response of sarcomas by histologic subtypes: a review with special emphasis given to results achieved with razoxane. Sarcoma; 2006;2006(1):87367
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  • The response rate is less than 50% in malignant fibrous histiocytomas, synovial, neurogenic, and other rare soft tissue sarcomas.

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  • (PMID = 17040092.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC1510952
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24. Pastor N, Bañuls J, Betlloch I, Pascual JC, Blanes M: [Fast-growing tumor on the scalp of a 78-year-old woman]. Actas Dermosifiliogr; 2005 Jun;96(5):323-4
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  • [Transliterated title] Tumoración de rápido crecimiento en el cuero cabelludo de una mujer de 78 años.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Scalp. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16476398.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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25. Beer TW, Drury P, Heenan PJ: Atypical fibroxanthoma: a histological and immunohistochemical review of 171 cases. Am J Dermatopathol; 2010 Aug;32(6):533-40
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  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology


26. Maier PC, Auw-Hädrich C, Reinhard T: [Recurrent fibrous histiocytoma at the corneoscleral limbus]. Klin Monbl Augenheilkd; 2008 Jan;225(1):99-100
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  • [Title] [Recurrent fibrous histiocytoma at the corneoscleral limbus].
  • [Transliterated title] Rezidivierendes fibröses Histiozytom am korneoskleralen Limbus.
  • This case report describes a rare fibrous histiocytoma at the corneoscleral limbus in a 10-year-old boy.
  • In our patient the tumour was histologically classified as benign, however, it presented with an invasive growth pattern and recurrency, so that a penetrating sclerokeratoplasty became necessary.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Keratoplasty, Penetrating. Limbus Corneae / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 18236380.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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27. Nooij MA, Whelan J, Bramwell VH, Taminiau AT, Cannon S, Hogendoorn PC, Pringle J, Uscinska BM, Weeden S, Kirkpatrick A, Glabbeke Mv, Craft AW, European Osteosarcoma Intergroup: Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study. Eur J Cancer; 2005 Jan;41(2):225-30
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  • [Title] Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study.
  • There are limited data that define the role of chemotherapy in the treatment of high-grade spindle cell sarcomas of bone, other than osteosarcoma or malignant fibrous histiocytoma (MFH-B).
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / drug therapy. Rare Diseases / drug therapy. Sarcoma / drug therapy


28. Katsuura Y, Ishida H, Komatsuda T, Furukawa K, Yagisawa H, Yamada M, Ohno H, Kotanagi H, Miyauchi T, Saitoh K: Malignant fibrous histiocytoma of the spleen: report of a case and literature review. Abdom Imaging; 2006 Jul-Aug;31(4):453-6
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  • [Title] Malignant fibrous histiocytoma of the spleen: report of a case and literature review.
  • There is a marked paucity of reports on malignant fibrous histiocytoma (MFH) of the spleen in the literature, and there are no previous reports of its color Doppler sonographic (US) and contrast-enhanced US findings.
  • We report on an 82-year-old male with splenic MFH (inflammatory subtype), with an emphasis on color Doppler and contrast-enhanced US findings.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / ultrasonography. Splenic Neoplasms / ultrasonography

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  • (PMID = 16447082.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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29. Lee JC, Christensen T, O'Hara CJ: Metastatic interdigitating dendritic cell sarcoma masquerading as a skin primary tumor: a case report and review of the literature. Am J Dermatopathol; 2009 Feb;31(1):88-93
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  • [Title] Metastatic interdigitating dendritic cell sarcoma masquerading as a skin primary tumor: a case report and review of the literature.
  • We report an unusual case of a lymph node interdigitating dendritic cell sarcoma (IDCS), metastatic to skin, in a 73-year-old patient.
  • The patient initially presented as having a primary skin tumor with lymph node metastasis.
  • Additional immunohistochemistry was performed on the shave biopsy, confirming that the skin tumor was a metastasis.
  • [MeSH-major] Dendritic Cell Sarcoma, Interdigitating / pathology. Lymph Nodes / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Aged. Diagnosis, Differential. Histiocytoma, Benign Fibrous / pathology. Humans. Hyperlipidemias / complications. Hypertension / complications. Immunohistochemistry. Neoplasms, Second Primary / pathology

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  • (PMID = 19155734.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Lehnhardt M, Daigeler A, Homann HH, Hauser J, Langer S, Steinsträsser L, Soimaru C, Puls A, Steinau HU: [Importance of specialized centers in diagnosis and treatment of extremity-soft tissue sarcomas. Review of 603 cases]. Chirurg; 2009 Apr;80(4):341-7
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  • Due to the disorder's rarity, multitude of subgroups, sometimes varying histopathologic appearance, and occasionally inadequate biopsy specimens, diagnosis and grading are challenging.
  • Liposarcoma and malignant fibrous histiocytoma were the most often diagnosed subgroups at 24% and 22.6%, respectively.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Diagnostic Errors. Female. Germany. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / diagnosis. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / diagnosis. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Staging. Nerve Sheath Neoplasms / diagnosis. Nerve Sheath Neoplasms / pathology. Nerve Sheath Neoplasms / surgery. Radiotherapy, Adjuvant. Referral and Consultation. Retrospective Studies. Young Adult

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  • (PMID = 18523742.001).
  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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31. Leow AM, Halim AS, Wan Z: Reconstructive treatment following resection of high-grade soft-tissue sarcomas of the lower limb. J Orthop Surg (Hong Kong); 2005 Apr;13(1):58-63
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  • RESULTS: Of 8 patients (6 women and 2 men) aged between 19 and 65 years, 4 had malignant fibrous histiocytoma, one had malignant peripheral nerve sheath tumour, one had synovial sarcoma, one had recurrent liposarcoma, and one had epitheloid sarcoma.

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  • (PMID = 15872402.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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32. Rzyman W, Jaskiewicz K, Murawski M, Sternau A, Marjanski T, Karmolinski A, Dziadziuszko R: Primary malignant fibrous histiocytoma of the lung. Thorac Cardiovasc Surg; 2007 Apr;55(3):186-9
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  • [Title] Primary malignant fibrous histiocytoma of the lung.
  • BACKGROUND: Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Pneumonectomy

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  • (PMID = 17410507.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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33. Min WK, Kim SY, Oh CW, Kim SJ, Park TI, Koo KH: Malignant fibrous histiocytoma arising in the area of total hip replacement. Joint Bone Spine; 2008 May;75(3):319-21
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  • [Title] Malignant fibrous histiocytoma arising in the area of total hip replacement.
  • The biopsy confirmed the malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Arthroplasty, Replacement, Hip / adverse effects. Femur Head Necrosis / surgery. Histiocytoma, Malignant Fibrous / etiology

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  • (PMID = 17977772.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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34. Choi KH, Baek HA, Park HS, Jang KY, Jin GY, Kim MH, Lee YC, Moon WS, Chung MJ: Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung. Pathol Int; 2008 Nov;58(11):735-40
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  • [Title] Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung.
  • Pulmonary sclerosing hemangioma is generally considered a rare neoplasm presenting as a solitary benign nodule.
  • During routine medical examination multiple abnormal nodular shadows were detected in the right lower lung field on chest X-ray in a 48-year-old asymptomatic woman.
  • All of these lesions had typical features of sclerosing hemangioma.
  • The authors call this unusual growth pattern of sclerosing hemangioma a 'pneumonic pattern'.
  • [MeSH-major] Adenoma / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 18844941.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1
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35. Utsunomiya D, Ikeda O, Ideta I, Hirayama T, Yamashita Y, Kamio T: Malignant fibrous histiocytoma arising from the aortic wall mimicking a pseudoaneurysm with ulceration. Circ J; 2007 Oct;71(10):1659-61
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  • [Title] Malignant fibrous histiocytoma arising from the aortic wall mimicking a pseudoaneurysm with ulceration.
  • Malignant fibrous histiocytoma of the thoracic aorta associated with ulcer-like projection has not been reported previously.
  • [MeSH-major] Aorta, Thoracic. Aortic Aneurysm, Thoracic / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Ulcer / diagnosis. Vascular Neoplasms / diagnosis

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  • (PMID = 17895569.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Sato A, Ishida H, Komatsuda T, Yagisawa H: Spontaneous ruptured hepatic malignant fibrous histiocytoma. J Med Ultrason (2001); 2006 Dec;33(4):255-6
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  • [Title] Spontaneous ruptured hepatic malignant fibrous histiocytoma.

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  • [Cites] Cancer. 1980 Jan 1;45(1):167-78 [6243239.001]
  • (PMID = 27277985.001).
  • [ISSN] 1346-4523
  • [Journal-full-title] Journal of medical ultrasonics (2001)
  • [ISO-abbreviation] J Med Ultrason (2001)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; liver tumor / malignant fibrous histiocytoma / rupture / ultrasound
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37. Lakhani P, Rubesin SE, Zhang PJ: Malignant fibrous histiocytoma of the pharynx. AJR Am J Roentgenol; 2005 Mar;184(3 Suppl):S12-3
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  • [Title] Malignant fibrous histiocytoma of the pharynx.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Pharyngeal Neoplasms / pathology

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  • (PMID = 15728001.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Maccauro G, Liuzza F, Muratori F, Gosheger G, Salgarello M, Logroscino CA: A particular solution in the treatment of primitive neoplasms of the distal third of the tibia. Presentation of a clinical case and review of the literature. Arch Orthop Trauma Surg; 2006 Dec;126(10):713-8
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  • The authors describe the diagnostic procedure and a particular surgical strategy of limb salvage in a case of malignant fibrous histiocytoma located at the distal third of the tibia, in particular pointing out the difficulties in restoring the continuity of the skeletal tissues and of the muscle, and with a review of the relevant literature.
  • [MeSH-major] Bone Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery. Salvage Therapy. Tibia

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  • (PMID = 16896746.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 37
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39. Kubo M, Ihn H, Yamane K, Tamaki K: The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans. Br J Dermatol; 2006 May;154(5):919-25
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  • [Title] The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans.
  • BACKGROUND: Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are benign and intermediate malignant fibrotic dermal tumours, respectively.
  • The contribution of transforming growth factor (TGF)-beta has been implicated in the progression of sclerosis in fibrotic diseases.
  • RESULTS: We detected strong expression of TGFbeta-RI and TGFbeta-RII on epidermis and epidermal appendages, moderate expression in vascular endothelial cells, smooth muscle cells and neural tissues, and weak expression in fibroblasts in normal skin sections.
  • Weak expression of TGF-beta1 was found on normal skin or tumour cells in the central part of DFSP.
  • CONCLUSIONS: These results suggest the possibility that TGF-beta signalling may contribute to the fibrosis around DF, and that TGF-beta receptors may play important roles in TGF-beta signalling.
  • The expression patterns of TGFbeta-RI and TGFbeta-RII may be helpful in distinguishing these diseases.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Neoplasm Proteins / metabolism. Receptors, Transforming Growth Factor beta / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Activin Receptors, Type I / genetics. Activin Receptors, Type I / metabolism. Adult. Biomarkers, Tumor / metabolism. Collagen Type I / metabolism. Diagnosis, Differential. Female. Humans. In Situ Hybridization. Male. Middle Aged. Protein-Serine-Threonine Kinases. RNA, Messenger / genetics. Skin / metabolism. Up-Regulation

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  • (PMID = 16634896.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / Receptors, Transforming Growth Factor beta; EC 2.7.1.11 / TGF-beta type I receptor; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / Activin Receptors, Type I; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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40. Conley AP, Trent J, Zhang W: Recent progress in the genomics of soft tissue sarcomas. Curr Opin Oncol; 2008 Jul;20(4):395-9
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  • Genomic analysis provides a means to elucidate new gene signatures or pathways for possible therapeutic manipulation, predictors of prognosis, and improved diagnostic classification.
  • RECENT FINDINGS: Genomic profiling of soft tissue sarcomas subtypes reveals a propensity for tumors of less karyotypic diversity to segregate from the more pleomorphic subtypes.
  • Certain statistical methods such as support vector machine analysis can distinguish pleomorphic subgroups such as malignant fibrous histiocytomas from other sarcomas.

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  • (PMID = 18525334.001).
  • [ISSN] 1531-703X
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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41. Kuroda K, Tajima S: Proliferation of HSP47-positive skin fibroblasts in dermatofibroma. J Cutan Pathol; 2008 Jan;35(1):21-6
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  • [Title] Proliferation of HSP47-positive skin fibroblasts in dermatofibroma.
  • BACKGROUND: The cell origin of dermatofibroma (DF) has not been clarified satisfactorily.
  • This study was undertaken to assess the distribution of fibroblasts and the relationship between fibroblasts and other constituent cells in DF by 47-kDa heat-shock protein (HSP47), a cell marker for skin fibroblast.
  • CONCLUSIONS: Skin fibroblast is one of the major constituent cells in DF, and DF may be composed chiefly of two types of cell lineages, fibroblasts and bone marrow-derived monocyte/macrophages (dermal dendritic cells and/or histiocytes).
  • [MeSH-major] Fibroblasts / metabolism. HSP47 Heat-Shock Proteins / metabolism. Histiocytoma, Benign Fibrous / metabolism. Skin / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 18095990.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD68 antigen, human; 0 / HSP47 Heat-Shock Proteins; 0 / SERPINH1 protein, human; EC 2.3.2.13 / Factor XIIIa
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42. King R, Googe PB, Page RN, Mihm MC Jr: Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ. Mod Pathol; 2005 Aug;18(8):1043-7
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  • [Title] Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ.
  • Dermatofibromas are common lesions that are often associated with epidermal hyperplasia and basal layer hyperpigmentation.
  • A single case of lentiginous melanocytic hyperplasia overlying a dermatofibroma has been reported, however, nevi and melanoma have to the best of our knowledge, not been previously reported.
  • We present 14 cases of melanocytic lesions associated with dermatofibromas.
  • The clinical diagnosis ranged from dermatofibroma to desmoplastic melanoma.
  • In four cases the dermal component appeared to merge with the dermatofibroma.
  • In the case of the melanoma in situ, the dermatofibroma abutted the epidermis.
  • Immunohistochemically, the melanocytic lesions were S-100/ Mart-1+, FXIIIa-, and the dermatofibromas were S-100/Mart-1-, FXIIIa+.
  • Melanocytic neoplasia may appear in association with dermatofibromas.
  • The fibrohistiocytic proliferation may be misinterpreted as a spindle or pleomorphic melanocytic process.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanocytes / pathology. Skin Neoplasms / pathology

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  • (PMID = 15803191.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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43. Collin F, Gelly-Marty M, Bui Nguyen Binh M, Coindre JM: [Soft tissue sarcomas: current data in the field of pathology]. Cancer Radiother; 2006 Feb-Mar;10(1-2):7-14
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  • New data led to the revision of the WHO classification.
  • Malignant fibrous histiocytoma is no longer considered as an entity.
  • Haemangiopericytoma underwent reappraisal and was put in the same category as solitary fibrous tumour.

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  • (PMID = 16310396.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 28
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44. Kuo FY, Eng HL, Chen SH, Huang HY: Intramuscular juvenile xanthogranuloma in an adult: a case report with immunohistochemical study. Arch Pathol Lab Med; 2005 Feb;129(2):e31-4
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  • Juvenile xanthogranuloma (JXG) is a self-limited cutaneous lesion that most often occurs in infancy.
  • Approximately 10% to 30% of JXGs occur in adult patients, where most cases present as cutaneous papulonodular lesions, with only rare cases involving extracutaneous sites.
  • The authors hereby describe a case of adult intramuscular JXG that occurred in a woman who initially had a dermal JXG in the nasal skin at the age of 48 years and then developed a slow-growing painless intramuscular JXG in the right forearm 4 years later.
  • However, central fibrosis and a focal storiform arrangement of spindled fibroblast-like cells in the intramuscular lesion resulted in a histologic pattern reminiscent of a fibrous histiocytoma.
  • This case underscores the fact that intramuscular JXG can also involve adult patients and its morphologic variation is more likely to be time dependent rather than site specific or age related.
  • [MeSH-major] Muscular Diseases / diagnosis. Xanthogranuloma, Juvenile / diagnosis
  • [MeSH-minor] Female. Humans. Middle Aged. Skin Diseases / pathology


45. Cox NH: Halo asteatotic eczema localized around a dermatofibroma in acute-onset leg oedema. Br J Dermatol; 2008 Aug;159(2):496
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  • [Title] Halo asteatotic eczema localized around a dermatofibroma in acute-onset leg oedema.
  • [MeSH-major] Eczema / pathology. Edema / pathology. Histiocytoma, Benign Fibrous / pathology. Leg Dermatoses / pathology. Skin Neoplasms / pathology


46. Guillou L: [Mesenchymal tumors of the skin. Atypical fibrous histiocytoma]. Ann Pathol; 2009 Oct;29(5):411-5
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  • [Title] [Mesenchymal tumors of the skin. Atypical fibrous histiocytoma].
  • [Transliterated title] Tumeurs conjonctives de la peau. Cas n(o) 7. Histiocytome fibreux atypique.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 20004844.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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47. Jarry J, Belleannee G, Laurent C, Coindre JM, Evrard S: Primary malignant fibrous histiocytoma of the pancreas: benefit of the multidisciplinary approach. Eur J Gastroenterol Hepatol; 2010 Jun;22(6):765-8
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  • [Title] Primary malignant fibrous histiocytoma of the pancreas: benefit of the multidisciplinary approach.
  • Primary malignant fibrous histiocytoma (MFH) is an exceedingly rare tumour of the pancreas with a high recurrence rate and a poor prognosis.
  • In this report, the authors present the case of a 45-year-old man who was first operated on for a primary MFH of the pancreas.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / therapy. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / therapy

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  • (PMID = 20446353.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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48. Wibmer C, Leithner A, Zielonke N, Sperl M, Windhager R: Increasing incidence rates of soft tissue sarcomas? A population-based epidemiologic study and literature review. Ann Oncol; 2010 May;21(5):1106-11
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  • The most common histotypes were sarcoma not otherwise specified (36%), leiomyosarcoma (24%), liposarcoma (12%), malignant fibrous histiocytoma (9%) and fibrosarcoma (5%).
  • CONCLUSIONS: This study has analyzed the most recent data from a European population in comparison with seven international studies.
  • The incidence rate of STS in Austria ranges in the lower half of the international incidence rates (1.8-5.0 per 100,000 per year).

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  • (PMID = 19858086.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 17
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49. Dei Tos AP: Classification of pleomorphic sarcomas: where are we now? Histopathology; 2006 Jan;48(1):51-62
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  • [Title] Classification of pleomorphic sarcomas: where are we now?
  • Until a decade ago, so-called pleomorphic and storiform malignant fibrous histiocytoma (MFH) represented the most frequently diagnosed sarcoma, accounting for approximately 40% of adult mesenchymal malignancies.
  • However, the latest World Health Organization classification of soft tissue tumours considers MFH a synonym for undifferentiated pleomorphic sarcoma.
  • With the advent of electron microscopy, immunohistochemistry and molecular genetics, it became clear that the so-called "facultative fibroblast" theory had no scientific grounds and, in 1992, a milestone paper eventually brought attention to the concept that MFH merely represented a morphological pattern shared by a wide variety of poorly differentiated malignant neoplasms, which include specific subtypes of pleomorphic sarcomas.
  • Currently, accurate subclassification of pleomorphic sarcomas is mandatory as it enables recognition of non-sarcomatous lesions as well as pleomorphic neoplasms not associated with aggressive behaviour.
  • Furthermore, as myogenic differentiation predicts aggressive clinical behaviour among pleomorphic sarcomas, precise histotyping allows prognostic stratification of patients.
  • [MeSH-major] Sarcoma / classification. Soft Tissue Neoplasms / classification

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  • (PMID = 16359537.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 63
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50. Sharma H, Jane MJ, Reid R: Scapulo-humeral Paget's sarcoma: Scottish Bone Tumour Registry experience. Eur J Cancer Care (Engl); 2005 Sep;14(4):367-72
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  • Histology showed predominantly osteosarcoma (n = 12), followed by pleomorphic sarcoma (n = 2), malignant fibrous histiocytoma (n = 1) and fibrosarcoma (n = 1).


51. Papagelopoulos PJ, Mavrogenis AF, Galanis EC, Chloros GD, Papaparaskeva KT: Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report. J Bone Joint Surg Am; 2005 Feb;87(2):399-403
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report.
  • [MeSH-major] Bone Neoplasms / pathology. Femur / pathology. Histiocytoma, Benign Fibrous / pathology. Neurofibromatosis 1 / pathology


52. Ismail Y, Watson S: Benign fibrous histiocytoma (dermatofibroma) of the face: a rare entity requiring aggressive surgical management. J Plast Reconstr Aesthet Surg; 2010 Aug;63(8):e647
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  • [Title] Benign fibrous histiocytoma (dermatofibroma) of the face: a rare entity requiring aggressive surgical management.
  • [MeSH-major] Facial Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery

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  • (PMID = 20378438.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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53. Venkataraman G, Hammadeh R: Report of an angiosarcoma mimic: cutaneous aneurysmal fibrous histiocytoma. APMIS; 2006 Oct;114(10):744-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Report of an angiosarcoma mimic: cutaneous aneurysmal fibrous histiocytoma.
  • Aneurysmal fibrous histiocytoma is an unusual variant of the spectrum of fibrous histiocytomas with the peculiar morphologic appearance of a benign aneurysmal vasoformative process that ultimately culminates in multiple microhemorrhages within the tumor.
  • It looks strikingly different from the usual cutaneous lesions encountered in clinical dermatology practice.
  • A single report of a cutaneous aneurysmal fibrous histiocytoma in the skin of the back of a 60-year-old male is described with emphasis on the immunostaining pattern and review of the literature.
  • There is a significant potential for confusion of this lesion with other cutaneous lesions, clinically as well as pathologically.
  • In our case, the patient presented with a lesion that clinically resembled a hemangioma, was pathologically interpreted initially to be an angiosarcoma, and finally, the revised pathology was interpreted as an aneurysmal variant of a fibrous histiocytoma.
  • Caution is warranted to avoid misinterpretation of cutaneous fibrohistiocytic tumors.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17004978.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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54. Gaumann A, Bode-Lesniewska B, Zimmermann DR, Fanburg-Smith JC, Kirkpatrick CJ, Hofstädter F, Woenckhaus M, Stoehr R, Obermann EC, Dietmaier W, Hartmann A: Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases. Virchows Arch; 2008 Nov;453(5):473-84
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  • [Title] Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases.
  • Pulmonary artery sarcoma (PAS) were studied by morphologic, immunohistochemical, and molecular genetic methods of the Wnt pathway.
  • PAS were classified as epithelioid (n = 4) or malignant fibrous histiocytoma (MFH; spindled/pleomorphic, n = 4), myxofibrosarcoma (n = 8), and one each hemangiopericytoma-like or malignant inflammatory myofibroblastic tumor-like.
  • [MeSH-major] Adenomatous Polyposis Coli Protein / metabolism. Pulmonary Artery / pathology. Sarcoma / classification. Signal Transduction / physiology. Tunica Intima / pathology. Vascular Neoplasms / classification. beta Catenin / metabolism

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  • (PMID = 18807072.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / Cyclin A; 0 / beta Catenin; 136601-57-5 / Cyclin D1
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55. O'Blenes CA, Walsh NM, Green PJ, Tremaine RD: Novel case of generalized multinucleate cell angiohistiocytoma. J Cutan Med Surg; 2010 Jul-Aug;14(4):178-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: multinucleate cell angiohistiocytoma is a rare benign fibrohistiocytic and vascular proliferation, typically characterized by the development of solitary papules, in an acral distribution in otherwise healthy late middle-aged to elderly women.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin / pathology

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  • (PMID = 20642987.001).
  • [ISSN] 1203-4754
  • [Journal-full-title] Journal of cutaneous medicine and surgery
  • [ISO-abbreviation] J Cutan Med Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Miura N, Shoji F, Kawano D, Morodomi Y, Ito K, Yano T, Maehara Y: A pulmonary sclerosing hemagioma with an increasing uptake on PET. Thorac Cardiovasc Surg; 2009 Dec;57(8):498-9
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  • [Title] A pulmonary sclerosing hemagioma with an increasing uptake on PET.
  • Pulmonary sclerosing hemangioma is a relatively rare neoplasm of the lung.
  • Although there have been five previous case reports that address the 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) findings in a sclerosing hemangioma of the lung, no report has demonstrated an interval change in the FDG-PET findings.
  • This report describes a case of pulmonary sclerosing hemangioma which presented with an increase of uptake of FDG-PET after about one years' follow-up.
  • [MeSH-major] Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography. Pulmonary Sclerosing Hemangioma / radionuclide imaging

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  • [Copyright] Copyright Georg Thieme Verlag KG Stuttgart . New York.
  • (PMID = 20013629.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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57. Benassi MS, Ponticelli F, Azzoni E, Gamberi G, Pazzaglia L, Chiechi A, Conti A, Spessotto P, Scapolan M, Pignotti E, Bacchini P, Picci P: Altered expression of urokinase-type plasminogen activator and plasminogen activator inhibitor in high-risk soft tissue sarcomas. Histol Histopathol; 2007 09;22(9):1017-24
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  • In recent years, classification of soft-tissue sarcomas (STS) has improved with cytogenetic analyses, but their clinical behavior is still not easily predictable.
  • Real-time PCR was performed on human STS cell lines and tissues from highly malignant STS, including leiomyosarcomas and malignant fibrous histiocytomas, to evaluate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1).

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  • (PMID = 17523079.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / PLAUR protein, human; 0 / Plasminogen Activator Inhibitor 1; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 0 / Receptors, Urokinase Plasminogen Activator; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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58. Monteagudo B, Alvarez-Fernández JC, Iglesias B, de las Heras C, Cacharrón JM: [Multiple eruptive dermatofribromas in a patient with Down's syndrome]. Actas Dermosifiliogr; 2005 Apr;96(3):199
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  • [Transliterated title] Dermatofibromas eruptivos múltiples en un paciente con síndrome de Down.
  • [MeSH-major] Down Syndrome / complications. Histiocytoma, Benign Fibrous / complications. Skin Neoplasms / complications

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  • (PMID = 16476369.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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59. Domson GF, Shahlaee A, Reith JD, Bush CH, Gibbs CP: Infarct-associated bone sarcomas. Clin Orthop Relat Res; 2009 Jul;467(7):1820-5
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  • Sixty percent of cases arise about the knee and most are malignant fibrous histiocytomas.
  • [MeSH-major] Bone Neoplasms / complications. Histiocytoma, Malignant Fibrous / complications. Infarction / complications. Sarcoma / complications

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  • (PMID = 19229663.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2690751
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60. Tse GM, Tan PH, Lui PC, Putti TC: Spindle cell lesions of the breast--the pathologic differential diagnosis. Breast Cancer Res Treat; 2008 May;109(2):199-207
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  • In the biphasic lesions with predominance of spindle cells with benign epithelial component, fibroepithelial lesions including fibroadenomas and phyllodes tumors are the most common, followed by pseudoangiomatous stromal hyperplasia, hamartoma and adenomyoepithelioma.
  • For monophasic lesions with pure pleomorphic spindle cell only, the monophasic metaplastic carcinoma is more common than the rare primary sarcomas like malignant fibrous histiocytoma, angiosarcoma, and other high grade sarcomas.

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  • (PMID = 17636400.001).
  • [ISSN] 0167-6806
  • [Journal-full-title] Breast cancer research and treatment
  • [ISO-abbreviation] Breast Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 57
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61. Ferrara G, Brasiello M, Annese P, Francione S, Giorgio CM, Moscarella E, Zalaudek I, Argenziano G: Desmoplastic nevus: clinicopathologic keynotes. Am J Dermatopathol; 2009 Oct;31(7):718-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Nevus / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Dermoscopy. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / pathology. Humans. Immunohistochemistry. Melanoma / pathology. Middle Aged. Nevus, Epithelioid and Spindle Cell / pathology

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  • (PMID = 19684509.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Wen QL, Meng MB, Zou BW, Lu Y: Malignant fibrous histiocytoma like pleomorphic leiomyosarcoma with laryngeal cancer as a second primary neoplasm: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):1013-7
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  • [Title] Malignant fibrous histiocytoma like pleomorphic leiomyosarcoma with laryngeal cancer as a second primary neoplasm: a case report.
  • Pleomorphic leiomyosarcoma (P-LMS) may be easily confused with a malignant fibrous histiocytoma (MFH) as both may share nonspecific morphologic features.
  • It is reported that the larynx is the most common site for a second primary neoplasm (SPN) in a patient with a head and neck malignancy, although an SPN of the larynx following a P-LMS is extremely rare.
  • FNA showed the presence of clustered, large tumor cells with clear, eosinophilic and ill-defined cytoplasm and pleomorphic nuclei.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Laryngeal Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Second Primary / pathology


63. Kaya G, Augsburger E, Chavaz P, Saurat JH: CD44 and hyaluronate expression in follicular mucinosis. J Cutan Pathol; 2006 Mar;33(3):227-30
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  • Stromal HA accumulation is associated with decreased or lost expression of CD44 in perifollicular solitary cutaneous myxoma, myxoid dermatofibroma, and dermatofibrosarcoma protuberans.
  • METHODS: We examined the expression of CD44 and HA in the skin biopsy specimens of 10 patients with follicular mucinosis by using CD44-specific antibodies and biotinylated HA-binding protein (HABP), respectively.

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  • (PMID = 16466510.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers; 0 / Mucins; 9004-61-9 / Hyaluronic Acid
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64. Thomas DM, O'Sullivan B, Gronchi A: Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management. Expert Rev Anticancer Ther; 2009 Aug;9(8):1145-57
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  • The most common adult subtypes are liposarcomas and leiomyosarcomas, followed by pleomorphic sarcoma/malignant fibros histiocytoma (an entity not always easily distinguishable from dedifferentiated liposarcoma).
  • Novel targeted therapeutic agents that target specific amplification or translocation products offer promise for subsets of these diseases.

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  • (PMID = 19671034.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 93
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65. Giovani P, Patrikidou A, Ntomouchtsis A, Meditskou S, Thuau H, Vahtsevanos K: Benign fibrous histiocytoma of the buccal mucosa: case report and literature review. Case Rep Med; 2010;2010:306148
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  • [Title] Benign fibrous histiocytoma of the buccal mucosa: case report and literature review.
  • Benign fibrous histiocytoma is an interesting and challenging entity even in its most usual, cutaneous presentation.

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  • (PMID = 20589214.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2892663
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66. Quatresooz P, Paquet P, Hermanns-Lê T, Piérard GE: Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review). Int J Mol Med; 2008 Oct;22(4):403-9
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  • [Title] Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review).
  • In normal skin, Factor XIIIa is expressed in specific dermal dendrocytes (DD) derived from the monocyte/macrophage lineage or from a mesenchymal origin.
  • DD are located predominantly around the microvasculature in the adventitial dermis, at the dermo-epidermal junction, and around skin appendages, but normally not within the epidermis.
  • Increased numbers of Factor XIIIa+ DD are present in a host of specific cutaneous inflammatory and fibrotic conditions.
  • In tumor pathology, immunophenotypic differences are found between dermatofibromas and other fibrohistiocytic entities, most notably dermatofibrosarcoma protuberans.
  • In addition, Factor XIIIa+ DD are likely to be involved in the progression and regression of some malignancies including cutaneous melanoma and basal cell carcinoma.
  • [MeSH-major] Dendritic Cells / metabolism. Factor XIIIa / metabolism. Skin / cytology

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  • (PMID = 18813845.001).
  • [ISSN] 1107-3756
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.3.2.13 / Factor XIIIa
  • [Number-of-references] 124
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67. Pu Q, Liu LX, Che GW, Wang Y, Kou YL, Ma L, Zhu YK, Mei JD: [The feasibility study in the treatment of benign pulmonary diseases by single-direction complete video-assisted thoracoscopic lobectomy]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2010 May;41(3):548-50
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  • [Title] [The feasibility study in the treatment of benign pulmonary diseases by single-direction complete video-assisted thoracoscopic lobectomy].
  • OBJECTIVE: To explore the feasibility and safety of single-direction video-assisted thoracoscopic lobectomy in the treatment of benign pulmonary diseases.
  • METHODS: From May 2006 to Dec 2009, 60 patients with benign pulmonary diseases were treated by single-direction complete video-assisted thoracoscopic lobectomy.
  • Nine cases were bronchiectasis, 7 bronchial cyst, 7 tuberculoma, 11 inflammatory pseudotumor, 6 sclerosing hemangioma, 4 hamartoma, 2 atelectasis with bronchial stenosis, 2 pulmonary aspergillosis, 2 pulmonary sequestration, 8 multiple bullae and 2 cases of mid-lobe syndrome.
  • CONCLUSION: Single-direction complete video-assisted thoracoscopic lobectomy is feasible and safe in the treatment of benign pulmonary diseases.
  • [MeSH-major] Lung Diseases / surgery. Pneumonectomy / methods. Thoracic Surgery, Video-Assisted / methods

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  • (PMID = 20629338.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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68. Vetter M, Germann G, Bickert B, Sauerbier M: Current strategies for sarcoma reconstruction at the forearm and hand. J Reconstr Microsurg; 2010 Sep;26(7):455-60
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  • The most common tumor type was the myxoid fibrous histiocytoma in 10 cases.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Child. Child, Preschool. Combined Modality Therapy. Disability Evaluation. Female. Fibula / transplantation. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Humans. Infant. Limb Salvage. Male. Microsurgery / methods. Middle Aged. Neoadjuvant Therapy. Neoplasm Recurrence, Local. Neoplasm Staging. Retrospective Studies. Surveys and Questionnaires

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  • [Copyright] (c) Thieme Medical Publishers.
  • (PMID = 20458673.001).
  • [ISSN] 1098-8947
  • [Journal-full-title] Journal of reconstructive microsurgery
  • [ISO-abbreviation] J Reconstr Microsurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Meis-Kindblom JM: Clear cell sarcoma of tendons and aponeuroses: a historical perspective and tribute to the man behind the entity. Adv Anat Pathol; 2006 Nov;13(6):286-92
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  • Ultrastructural and immunohistochemical studies have shown melanocytic differentiation, whereas molecular genetic studies have shown cytogenetic rearrangements resulting in a EWSR1-ATF1 fusion gene that is characteristic but not entirely unique for clear cell sarcoma (similar fusion genes are also seen in angiomatoid fibrous histiocytoma).
  • Detection of this fusion gene and the absence of BRAF gene mutations clearly distinguish clear cell sarcoma from cutaneous melanoma.
  • [MeSH-major] Medical Oncology / history. Pathology / history. Sarcoma, Clear Cell / pathology. Soft Tissue Neoplasms / pathology. Tendons

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  • (PMID = 17075294.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits; Review
  • [Publication-country] United States
  • [Number-of-references] 33
  • [Personal-name-as-subject] Enzinger F
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70. Chan I, Robson A, Mellerio JE: Multiple dermatofibromas associated with lupus profundus. Clin Exp Dermatol; 2005 Mar;30(2):128-30
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  • [Title] Multiple dermatofibromas associated with lupus profundus.
  • We report a 58-year-old Afro-Caribbean woman who presented with more than 20 dermatofibromas on the body particularly on the back, arms and legs.
  • Multiple dermatofibromas are rare.
  • There are around 30 reports of multiple dermatofibromas associated with systemic diseases.
  • Although the mechanism is unknown, it appears that multiple dermatofibromas are associated with autoimmune diseases or altered immune states.
  • This is the first case of multiple dermatofibromas associated with lupus profundus.
  • The knowledge of such associations may contribute to the understanding of the pathogenesis of dermatofibromas, which is as yet unknown.
  • [MeSH-major] Histiocytoma, Benign Fibrous / etiology. Panniculitis, Lupus Erythematosus / complications
  • [MeSH-minor] Autoimmune Diseases / complications. Autoimmune Diseases / pathology. Female. Humans. Middle Aged

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  • (PMID = 15725236.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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71. Kim BG, Chang IT, Park JS, Choi YS, Kim GH, Park ES, Choi CH: Transanal excision of a malignant fibrous histiocytoma of anal canal: a case report and literature review. World J Gastroenterol; 2008 Mar 7;14(9):1459-62
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  • [Title] Transanal excision of a malignant fibrous histiocytoma of anal canal: a case report and literature review.
  • Malignant fibrous histiocytoma, which is composed of spindle-shaped cells arranged in a pleomorphic and storiform pattern, is rarely found in the colorectum.
  • We report a case of a 63-year-old woman with an ulcerative lesion in the anorectal junction and a final diagnosis of malignant fibrous histiocytoma.
  • To our knowledge, this is the first case reported in the English literature of a malignant fibrous histiocytoma treated with the transanal local excision and adjuvant radiotherapy.
  • This report showed that this approach is selectively reserved for early-stage malignant fibrous histiocytoma and for those patients who refuse radical surgery because of the risk in a permanent colostomy.
  • [MeSH-major] Anus Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery. Proctoscopy / methods

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  • (PMID = 18322967.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 29
  • [Other-IDs] NLM/ PMC2693701
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72. Sak SD, Koseoglu RD, Demirag F, Akbulut H, Gungor A: Alveolar adenoma of the lung. Immunohistochemical and flow cytometric characteristics of two new cases and a review of the literature. APMIS; 2007 Dec;115(12):1443-9
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  • Alveolar adenoma is a rare and benign tumour of the lung that usually presents in asymptomatic patients as a coin lesion on chest radiography.
  • Immunohistochemical analysis may aid in the characterization of alveolar adenoma and discriminate this condition from other types of benign lesions of the lung.
  • An indolent clinical progression and absence of recurrence and metastasis after complete resection are the most important characteristics indicative of the benign nature of alveolar adenoma.
  • Differential diagnoses include sclerosing hemangioma, papillary adenoma, lymphangioma, atypical adenomatous hyperplasia and bronchioloalveolar carcinoma.

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  • (PMID = 18184418.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
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73. Clarke JT, Clarke LE, Miller C, Helm KF, Zaenglein AL: Plaque-like myofibroblastic tumor of infancy. Pediatr Dermatol; 2007 Sep-Oct;24(5):E83-7
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  • These tumors histologically resembled dermatofibromas, but the young age of onset, large size, and plaque-like morphology were distinctly different from those of dermatofibromas.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasms, Muscle Tissue / pathology. Skin Neoplasms / pathology

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  • (PMID = 17958789.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Choudhury M, Nangia A, Singh SK, Pujani M, Thomas S: Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):985-8
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  • [Title] Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report.
  • CASE: A case of recurrent primary malignant fibrous histiocytoma (MFH) occurred in the breast in a 32-year-old woman.
  • CONCLUSION: Malignant fibrous histiocytoma of the breast is a rare entity, and a complete clinicopathologic correlation with immunohistochemical profile is essential to arrive at a correct diagnosis and guide appropriate management of the patient.
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology

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  • (PMID = 21053583.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Nonaka D: A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). Histopathology; 2008 Jun;52(7):896-7
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  • [Title] A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Dendritic Cells / metabolism. Histiocytoma, Benign Fibrous / pathology. Monocytes / metabolism. Skin Neoplasms / pathology

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  • (PMID = 18462367.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.3.2.13 / Factor XIIIa
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76. Fine SW, Lisanti MP, Argani P, Li M: Caveolin-3 is a sensitive and specific marker for rhabdomyosarcoma. Appl Immunohistochem Mol Morphol; 2005 Sep;13(3):231-6
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  • Fifty-four other neoplasms (13 leiomyosarcomas, 8 neuroblastomas, 5 lymphomas, 6 Wilms tumors without skeletal muscle differentiation, 5 Ewing sarcomas, 4 malignant fibrous histiocytomas, 4 angiosarcomas, 6 malignant melanomas, and 3 synovial sarcomas) were negative for Cav-3 expression.

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  • (PMID = 16082247.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MyoD Protein; 0 / MyoD1 myogenic differentiation protein; 0 / Myogenin
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77. Agero AL, Taliercio S, Dusza SW, Salaro C, Chu P, Marghoob AA: Conventional and polarized dermoscopy features of dermatofibroma. Arch Dermatol; 2006 Nov;142(11):1431-7
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  • [Title] Conventional and polarized dermoscopy features of dermatofibroma.
  • OBJECTIVE: To evaluate dermoscopic features and patterns of dermatofibromas using conventional and polarized light dermoscopy.
  • DESIGN: Dermatofibromas were imaged using conventional nonpolarized contact dermoscopy (NPD), polarized contact dermoscopy (PCD), and polarized noncontact dermoscopy, followed by evaluation and comparison of dermoscopic features of the lesions.
  • Patients Fifty patients with dermatofibromas.
  • RESULTS: The most common features of dermatofibromas observed with NPD and PCD were central white scarlike patches (37 [74%] and 42 [84%], respectively), brown globulelike structures (21 [42%] and 22 [44%]), vascular structures (24 [48%] and 22 [44%]), and a peripheral fine pigmented network (36 [72%] for both).
  • These new criteria can aid in the diagnosis of dermatofibroma.
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17116833.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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78. Zaiden R, Latif N, Pham D, Hosenpud J: Dermatofibroma protuberans arising from an infected insect bite. Clin Adv Hematol Oncol; 2009 Jun;7(6):404-8
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  • [Title] Dermatofibroma protuberans arising from an infected insect bite.
  • [MeSH-major] Dermatofibrosarcoma / etiology. Insect Bites and Stings / complications. Skin Neoplasms / etiology. Wound Infection / complications

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  • [CommentIn] Clin Adv Hematol Oncol. 2009 Jun;7(6):406-8 [19606077.001]
  • (PMID = 19606076.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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79. Hallor KH, Sciot R, Staaf J, Heidenblad M, Rydholm A, Bauer HC, Aström K, Domanski HA, Meis JM, Kindblom LG, Panagopoulos I, Mandahl N, Mertens F: Two genetic pathways, t(1;10) and amplification of 3p11-12, in myxoinflammatory fibroblastic sarcoma, haemosiderotic fibrolipomatous tumour, and morphologically similar lesions. J Pathol; 2009 Apr;217(5):716-27
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  • To further characterize these aberrations, we have investigated eight soft tissue sarcomas diagnosed as MIFS, haemosiderotic fibrolipomatous tumour (HFT), myxoid spindle cell/pleomorphic sarcoma with MIFS features, and inflammatory malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma with prominent inflammation (IMFH) harbouring a t(1;10) or variants thereof and/or ring chromosomes with possible involvement of chromosome 3.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 10 / genetics. Chromosomes, Human, Pair 3 / genetics. Female. Gene Expression Profiling / methods. Hemosiderosis / genetics. Histiocytoma, Malignant Fibrous / genetics. Histiocytoma, Malignant Fibrous / pathology. Humans. In Situ Hybridization, Fluorescence / methods. Karyotyping. Lower Extremity. Male. Middle Aged. Oligonucleotide Array Sequence Analysis / methods. Reverse Transcriptase Polymerase Chain Reaction / methods. Ring Chromosomes. Translocation, Genetic

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  • (PMID = 19199331.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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80. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, Bonichon F, Stoeckle E, Bui NB: Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas. Cancer; 2006 Jun 15;106(12):2725-33
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  • [Title] Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas.
  • Malignant fibrous histiocytoma (MFH) is no longer considered a homogeneous entity, but rather as the common morphologic appearance of various subtypes of sarcomas.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16688768.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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81. Keylock JB, Galvin JR, Franks TJ: Sclerosing hemangioma of the lung. Arch Pathol Lab Med; 2009 May;133(5):820-5
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  • [Title] Sclerosing hemangioma of the lung.
  • We present a brief review of sclerosing hemangioma, an uncommon but histologically distinctive neoplasm of the lung.
  • Based on immunohistochemical and molecular findings, sclerosing hemangioma is thought to be derived from incompletely differentiated respiratory epithelium.
  • Sclerosing hemangiomas typically present as asymptomatic, peripheral, solitary, well-circumscribed lesions in women with a mean age at diagnosis in the fifth decade.
  • Histologically, sclerosing hemangioma is characterized by a distinct constellation of findings including 2 epithelial cell types, surface cells and round cells, which form 4 architectural patterns, papillary, sclerotic, solid, and hemorrhagic.
  • Sclerosing hemangioma of the lung is generally considered to be a benign lesion, and surgical excision is curative without the need for additional treatment.
  • [MeSH-major] Lung / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 19415961.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 29
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82. Ding Y, Boguslawski EA, Berghuis BD, Young JJ, Zhang Z, Hardy K, Furge K, Kort E, Frankel AE, Hay RV, Resau JH, Duesbery NS: Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma. Mol Cancer Ther; 2008 Mar;7(3):648-58
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  • Similar results were obtained with cell lines derived from malignant fibrous histiocytomas, leiomyosarcomas, and liposarcomas.

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  • (PMID = 18319331.001).
  • [ISSN] 1535-7163
  • [Journal-full-title] Molecular cancer therapeutics
  • [ISO-abbreviation] Mol. Cancer Ther.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA 109308
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Bacterial; 0 / Bacterial Toxins; 0 / anthrax toxin; EC 2.7.11.24 / Mitogen-Activated Protein Kinases
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83. Tsukahara T, Kawaguchi S, Torigoe T, Asanuma H, Nakazawa E, Shimozawa K, Nabeta Y, Kimura S, Kaya M, Nagoya S, Wada T, Yamashita T, Sato N: Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5. Cancer Sci; 2006 Dec;97(12):1374-80
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  • In contrast, such prognostic significance of HLA class I expression was not found in 15 patients with malignant fibrous histiocytoma of soft tissue.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Histiocytoma, Malignant Fibrous / immunology. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / secondary. Humans. Immunoenzyme Techniques. Lymphocytes, Tumor-Infiltrating / immunology. Male. Middle Aged. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. RNA, Neoplasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Sarcoma / immunology. Sarcoma / metabolism. Sarcoma / secondary. Soft Tissue Neoplasms / immunology. Soft Tissue Neoplasms / metabolism. Soft Tissue Neoplasms / pathology. Survival Rate. T-Lymphocytes, Cytotoxic / immunology. beta 2-Microglobulin / genetics. beta 2-Microglobulin / immunology. beta 2-Microglobulin / metabolism

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  • (PMID = 16995877.001).
  • [ISSN] 1347-9032
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Histocompatibility Antigens Class I; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / beta 2-Microglobulin
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84. Fujimura T, Okuyama R, Tagami H, Aiba S: Angioleiomyoma with the features of the dermatofibroma. J Dermatol; 2008 Feb;35(2):124-5
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  • [Title] Angioleiomyoma with the features of the dermatofibroma.
  • [MeSH-major] Angiomyoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18271812.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Japan
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85. Marcet S: Atypical fibroxanthoma/malignant fibrous histiocytoma. Dermatol Ther; 2008 Nov-Dec;21(6):424-7
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  • [Title] Atypical fibroxanthoma/malignant fibrous histiocytoma.
  • Atypical fibroxanthoma (AFX) is an unusual spindle cell tumor occurring on actinically damaged skin of the head and neck.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Skin Neoplasms / pathology


86. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Title] Malignant fibrous histiocytoma of the conjunctiva.
  • Fibrous histiocytomas are mesenchymal tumours composed of cells with fibroblastic to histiocytic differentiation.
  • To date, there are 18 cases of fibrous histiocytoma arising from the corneoscleral limbus reported in the literature.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • Herein, the clinicopathological features of a case of malignant fibrous histiocytoma are presented and its management with wide excision and cryotherapy followed by ocular reconstruction with amniotic membrane transplant is discussed.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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87. Sutthiruangwong P, Thanakit V, Assavamongkolkul A: Angiomatoid fibrous histiocytoma with pain in a child. J Med Assoc Thai; 2005 Oct;88(10):1453-7
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  • [Title] Angiomatoid fibrous histiocytoma with pain in a child.
  • Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor with low-grade malignancy which occurs chiefly in children and young adults.
  • Clinically, the tumor appears as a cutaneous nodule with slow growth.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / complications. Pain / etiology. Soft Tissue Neoplasms / complications. Subcutaneous Tissue

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  • (PMID = 16519396.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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88. Lee KJ, Yang JM, Lee ES, Lee DY, Jang KT: CD10 is expressed in dermatofibromas. Br J Dermatol; 2006 Sep;155(3):632-3
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  • [Title] CD10 is expressed in dermatofibromas.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Histiocytoma, Benign Fibrous / metabolism. Neprilysin / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 16911298.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; EC 3.4.24.11 / Neprilysin
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89. Amico P, Vecchio GM, Bisceglia M, Vasquez E, Magro G: Atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component. Histogenetic considerations in the wide spectrum of fibrohistiocytic dermal tumours. Pathologica; 2010 Jun;102(3):115-8
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  • [Title] Atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component. Histogenetic considerations in the wide spectrum of fibrohistiocytic dermal tumours.
  • Atypical and epithelioid cell variants of dermatofibroma may represent a potential diagnostic pitfall.
  • Only rarely atypical dermatofibroma may show focal epithelioid cell features.
  • We herein report a rare case of dermatofibroma composed of a predominant (> 90%) epithelioid/deciduoid-like cell component, in which rare multinucleated bizarre cells and atypical mitoses were additional findings.
  • Tumour was classified as "atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component".
  • The coexistence of at least two different variants, i.e. epithelioid and atypical variants, in the same dermatofibroma suggests that dermal fibrohistiocytic tumours belong to a continuous morphological spectrum.
  • Accordingly, the morphological variants of dermatofibroma should be regarded as variations on a common basic theme.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Malignant Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 21171517.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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90. Ajlan AM, Sayegh K, Powell T, David H, Riha RM, Khan J, Nahal A: Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases. J Comput Assist Tomogr; 2010 Sep-Oct;34(5):791-4
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  • [Title] Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases.
  • OBJECTIVE: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor usually affecting the extremities of children and young adults and has a favorable prognosis.
  • CONCLUSIONS: Although the overall features of AFH can be confused with other subtypes of malignant fibrous histiocytoma, the young age at presentation, the location of the mass, the presence of intralesional blood-filled cystic spaces with fluid-fluid levels, associated features of hemosiderin deposition, and an enhancing fibrous pseudocapsule are all potential hints favoring this entity.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 20861788.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Yang S, Jeung HC, Jeong HJ, Choi YH, Kim JE, Jung JJ, Rha SY, Yang WI, Chung HC: Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer. Genomics; 2007 Apr;89(4):451-9
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  • The selected genes include those that were previously identified as being tumor suppressors or deleted in various tumors, including GATA binding protein 4 (GATA4), monoamine oxidase A (MAOA), cyclin C (CCNC), and oncogenes including malignant fibrous histiocytoma amplified sequence 1 (MFHAS1/MASL1), high mobility group AT-hook 2 (HMGA2), PPAR binding protein (PPARBP), growth factor receptor-bound protein 7 (GRB7), and TBC1 (tre-2, BUB2, cdc16) domain family, member 1 (TBC1D1).

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  • (PMID = 17229543.001).
  • [ISSN] 0888-7543
  • [Journal-full-title] Genomics
  • [ISO-abbreviation] Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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92. Cardinale L, Ardissone F, Familiari U, Perna M, Fava C: A case of intermittent lumbar pain radiating to the right shoulder in a 76-year-old woman. Eur Radiol; 2009 Sep;19(9):2315-9
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  • Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma, occurring most frequently in the deep soft tissues of the extremities, and it is most frequently seen in elderly patients.
  • [MeSH-major] Diaphragm / pathology. Histiocytoma, Malignant Fibrous / diagnostic imaging. Muscle Neoplasms / diagnostic imaging

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  • (PMID = 19626327.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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93. Puhaindran ME, Pratt J, Manoso MW, Healey JH, Mintz DN, Athanasian EA: Predictive value of magnetic resonance imaging in determining presence of residual disease after marginal excision of unsuspected soft tissue sarcomas of the hand. J Hand Surg Am; 2010 Sep;35(9):1479-84
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  • PURPOSE: Diagnosis of a soft tissue sarcoma of the hand is at times made only in retrospect after marginal excision of a presumed benign soft tissue mass.
  • RESULTS: There were 8 epithelioid sarcomas, 6 synovial sarcomas, 4 malignant fibrous histiocytomas, 2 leiomyosarcomas, 2 liposarcomas, 2 myxofibrosarcomas, and one each of 9 other diagnoses.

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  • [Copyright] Copyright 2010. Published by Elsevier Inc.
  • (PMID = 20807625.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Papalas JA, Balmer NN, Wallace C, Sangüeza OP: Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review. Am J Dermatopathol; 2009 Jun;31(4):379-83
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  • [Title] Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review.
  • Dermatofibromas are fibrohistiocytic lesions with numerous histologic variants.
  • Ossifying dermatofibroma with osteoclast-like giant cells is an uncommon variant that has only rarely been reported.
  • We report another case of ossifying dermatofibroma with osteoclast-like giant cells and describe the immunohistochemical expression pattern of these rare lesions.
  • Large islands of spindled cells arranged in a storiform pattern were separated by broad fibrous bands.
  • A broad differential diagnosis, including variants of melanoma and osteosarcoma, should be considered when analyzing cutaneous lesions with a fibrohistiocytic component admixed with giant cells and metaplastic bone.
  • [MeSH-major] Giant Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Ossification, Heterotopic / pathology. Osteoclasts / pathology. Skin Neoplasms / pathology

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  • (PMID = 19461244.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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95. Bharath C, Williams S: Benign fibrous histiocytoma of the nose. J Otolaryngol; 2005 Aug;34(4):253-4
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  • [Title] Benign fibrous histiocytoma of the nose.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Nose Neoplasms / diagnosis. Nose Neoplasms / pathology

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  • (PMID = 16048697.001).
  • [ISSN] 0381-6605
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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96. Schmidt JM, North SM, Freeman KP, Ramiro-Ibañez F: Canine paediatric oncology: retrospective assessment of 9522 tumours in dogs up to 12 months (1993-2008). Vet Comp Oncol; 2010 Dec;8(4):283-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Canine paediatric oncology: retrospective assessment of 9522 tumours in dogs up to 12 months (1993-2008).
  • Canine cutaneous histiocytoma (n = 8465; 89%) was the most common histological type.
  • Neoplasms other than histiocytoma (n = 1057; 11%) were grouped as benign epithelial (n = 375; 4%), haematopoietic (n = 229; 2%), benign mesenchymal (n = 145; 2%), miscellaneous (n = 118; 1%), non-hematopoietic malignant mesenchymal (n = 118; 1%) or malignant epithelial tumours (n = 72; <1%).
  • Excluding canine cutaneous histiocytoma, 52% of tumours (n = 547) were benign, and 66% were from the skin or soft tissues.
  • [MeSH-major] Aging. Dog Diseases / diagnosis. Neoplasms / veterinary

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 21062410.001).
  • [ISSN] 1476-5829
  • [Journal-full-title] Veterinary and comparative oncology
  • [ISO-abbreviation] Vet Comp Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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97. Kimyai-Asadi A, Goldberg LH, Greenberg C, Rabin V, Parry R, Batres E, Jih MH: Cellular, atypical, and indeterminate dermatofibromas: benign or malignant? Dermatol Surg; 2008 Sep;34(9):1264-71; discussion 1271-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cellular, atypical, and indeterminate dermatofibromas: benign or malignant?
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 18554287.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Lin N, Urabe K, Moroi Y, Uchi H, Nakahara T, Dainichi T, Kokuba H, Tu Y, Furue M: Overexpression of phosphorylated-STAT3 and phosphorylated-ERK protein in dermatofibrosarcoma protuberans. Eur J Dermatol; 2006 May-Jun;16(3):262-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The expressions of p-STAT3 and p-ERK were analyzed by immunohistochemical staining in formalin-fixed, paraffin-embedded tissue sections of human DFSP and dermatofibroma.
  • Ten cases were positive for p-STAT3 expression in 14 cases of DFSP, however, only 5 cases were positive in 20 cases of dermatofibroma.
  • Eleven out of 14 cases of DFSP expressed p-ERK, but only four cases were positive in 20 cases of dermatofibroma.
  • The expressions of p-STAT3 and p-ERK were significantly higher than those in dermatofibroma (both p < 0.01).
  • [MeSH-major] Extracellular Signal-Regulated MAP Kinases / metabolism. Histiocytoma, Benign Fibrous / metabolism. STAT3 Transcription Factor / metabolism

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  • (PMID = 16709490.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / STAT3 Transcription Factor; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases
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99. Mandal S, Mandal AK: Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma. Int J Clin Oncol; 2007 Feb;12(1):52-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.
  • Malignant fibrous histiocytoma (MFH) originates from primitive mesenchymal cells and has the capacity for dual differentiation into histiocytes and fibroblasts.
  • [MeSH-major] Bone Neoplasms / etiology. Histiocytoma, Malignant Fibrous / etiology. Hodgkin Disease / therapy. Muscle Neoplasms / etiology


100. Kideryová L, Lacina L, Dvoránková B, Stork J, Cada Z, Szabo P, André S, Kaltner H, Gabius HJ, Smetana K Jr: Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts. J Dermatol Sci; 2009 Jul;55(1):18-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts.
  • BACKGROUND: Benign and malignant fibrous histiocytoma present with a considerable difference concerning cellular organization in their vicinity.
  • OBJECTIVE: Normally appearing epithelium covers the malignant form in contrast to hyperplastic epidermis for benign tumors.
  • METHODS: Fibroblasts were isolated from benign and malignant fibrous histiocytomas, respectively, and also from normal dermis.
  • Cells prepared from benign fibrous histiocytoma were capable to effect strong expression of keratin 19 and production of a galectin-1-rich extracellular matrix.
  • Fibroblasts isolated from malignant fibrous histiocytoma led to a phenotype very similar to that when keratinocytes were cocultured with normal dermal fibroblasts.
  • CONCLUSION: Fibroblasts prepared from benign fibrous histiocytoma were biologically active on keratinocytes in a particular manner.
  • Our results on fibroblast activity are suggested to be relevant for morphologic differences observed in vivo between normal epidermis and epidermis adjacent to the studied tumor types.
  • [MeSH-major] Fibroblasts / pathology. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Malignant Fibrous / pathology. Keratinocytes / pathology. Skin Neoplasms / pathology






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