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Items 1 to 100 of about 919
1. Lang KJ, Lidder S, Hofer M, Graham C, Taylor A: Rapidly evolving giant dermatofibroma. Case Rep Med; 2010;2010:620910

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapidly evolving giant dermatofibroma.
  • Dermatofibroma, also known as "fibrous histiocytoma", is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis.
  • Histological examination confirmed this to be a giant dermatofibroma.
  • Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases.
  • The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion.

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  • [Cites] Clin Adv Hematol Oncol. 2009 Jun;7(6):404-8 [19606076.001]
  • [Cites] Actas Dermosifiliogr. 2007 Mar;98(2):121-4 [17397601.001]
  • [Cites] J R Coll Surg Edinb. 2000 Apr;45(2):132-4 [10822924.001]
  • [Cites] Int J Surg Pathol. 2004 Oct;12(4):333-44 [15494859.001]
  • [Cites] J Am Acad Dermatol. 1994 May;30(5 Pt 1):714-8 [8176009.001]
  • (PMID = 20224764.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2836174
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2. Bermejo Casero E, Pérez Alonso D, Quevedo Losada S, López Rivero L: [Dermatofibroma metastasizing to the lung: current treatment]. Arch Bronconeumol; 2009 Oct;45(10):521-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Dermatofibroma metastasizing to the lung: current treatment].
  • [Transliterated title] Dermatofibroma y metástasis pulmonares. Tratamiento actual.
  • They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm.
  • We present the case of a young woman with a recurrent dermatofibroma on the shoulder that metastasized to both lungs.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 19394746.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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3. Bandarchi B, Ma L, Marginean C, Hafezi S, Zubovits J, Rasty G: D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans. Mod Pathol; 2010 Mar;23(3):434-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans.
  • The distinction between dermatofibroma, particularly cellular variant, and dermatofibrosarcoma protuberans in excisional biopsies is usually straightforward.
  • Although factor XIIIa and CD34 immunostains are useful in differentiating dermatofibroma and dermatofibrosarcoma protuberans in most instances, focal CD34 positivity may be seen in cellular fibrous histiocytoma.
  • In this study, we investigated the utility of D2-40 in separating dermatofibroma from dermatofibrosarcoma protuberans and compared the results with other commonly used immunostains.
  • Fifty-six cases of dermatofibroma (including six cellular variant) and 29 cases of dermatofibrosarcoma protuberans were retrieved from the archives of Department of Anatomic Pathology at Sunnybrook Health Sciences Center in University of Toronto.
  • All 56 (100%) cases of dermatofibroma demonstrated strong and diffuse immunoreactivity to D2-40 in the spindle cells and stroma.
  • [MeSH-major] Antibodies, Monoclonal / analysis. Biomarkers, Tumor / analysis. Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis

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  • (PMID = 20062007.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40; EC 2.3.2.13 / Factor XIIIa
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4. Córdoba S, Hernández A, Romero A, Arias D, Castaño E, García-Donoso C, Borbujo JM: [Basal cell carcinoma overlying a dermatofibroma]. Actas Dermosifiliogr; 2005 Nov;96(9):612-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Basal cell carcinoma overlying a dermatofibroma].
  • [Transliterated title] Carcinoma basocelular sobre dermatofibroma.
  • The epidermis over a dermatofibroma may show changes that range from simple hyperplasia to the proliferation of basaloid cells, which can become morphologically indistinguishable from basal cell carcinoma.
  • The existence of a true basal cell carcinoma overlying a dermatofibroma is infrequent.
  • These basaloid proliferations have usually been considered to be the result of the inductive effect of the fibrohistiocytic proliferation of the dermatofibroma on the epithelial cells of the hair follicle; therefore, it would be a reactive phenomenon and not truly neoplastic.
  • We describe a case of dermatofibroma that presented with a basaloid proliferation identical in appearance to a basal cell carcinoma on the overlying epidermis.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Histiocytoma, Benign Fibrous / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476308.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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5. Hueso L, Sanmartín O, Alfaro-Rubio A, Serra-Guillén C, Martorell A, Llombart B, Requena C, Nagore E, Botella-Estrada R, Guillén C: [Giant dermatofibroma: case report and review of the literature]. Actas Dermosifiliogr; 2007 Mar;98(2):121-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant dermatofibroma: case report and review of the literature].
  • [Transliterated title] Dermatofibroma gigante: descripción de un caso y revisión de la literatura.
  • Dermatofibroma is a very frequent lesion that usually appears as a slowly growing nodule in the dermis, and preferentially involves the lower extremities of women.
  • Giant dermatofibroma has been defined as a rare variant of dermatofibroma measuring more than 5 cm that presents typical histological features and a benign biological behavior.
  • We report the case of a 52-year-old man that presented a giant dermatofibroma with a diameter of 6 cm in the right shoulder and we review the few cases of this variant that have been described in the literature.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17397601.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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6. Aydin E, Vardareli OS, Bilezikçi B, Ozgirgin ON: [Dermatofibroma accompanied by perforating dermatosis in the auricle: a case report]. Kulak Burun Bogaz Ihtis Derg; 2005;15(3-4):83-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Dermatofibroma accompanied by perforating dermatosis in the auricle: a case report].
  • [Transliterated title] Aurikulada dermatofibroma eşlik eden perforan dermatoz: Olgu sunumu.
  • Although dermatofibroma is one of the most common soft tissue tumors, it is rarely seen in the face.
  • Total excisional biopsy was performed, which showed dermatofibroma accompanied by perforating dermatosis.
  • Our literature search did not yield any reported case of dermatofibroma accompanied by perforating dermatosis.
  • [MeSH-major] Dermatitis / diagnosis. Ear, External / pathology. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16340298.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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7. Xiong Y, Guo H, Zhang S, Zhang B, Li T: [Differences of the molecular phenotypes and the histogenesis between dermatofibroma and dermatofibrosarcoma protuberans]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):395-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Differences of the molecular phenotypes and the histogenesis between dermatofibroma and dermatofibrosarcoma protuberans].
  • OBJECTIVE: To explore the histogenesis and differentiation of dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP).
  • DF is a benign tumor, while DFSP a low grade malignant tumor.
  • [MeSH-major] Antigens, CD34 / metabolism. Dermatofibrosarcoma / genetics. Factor XIIIa / metabolism. Histiocytoma, Benign Fibrous / genetics

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  • (PMID = 18677387.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD34; EC 2.3.2.13 / Factor XIIIa
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8. Demir MK, Ozdemir H, Gençhallaç H, Altaner S, Kartal O: Dermatofibroma mimicking malignancy on integrated F-18 fluorodeoxyglucose PET-CT. Diagn Interv Radiol; 2009 Mar;15(1):61-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma mimicking malignancy on integrated F-18 fluorodeoxyglucose PET-CT.
  • The pathologic diagnosis was dermatofibroma.
  • Although benign, dermatofibromas can have intense FDG uptake.
  • [MeSH-major] Fluorodeoxyglucose F18. Histiocytoma, Benign Fibrous / radionuclide imaging. Positron-Emission Tomography / methods. Radiopharmaceuticals. Skin Neoplasms / radionuclide imaging

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  • (PMID = 19263377.001).
  • [ISSN] 1305-3612
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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9. González-Vilas D, García-Gavín J, Ginarte M, Rodríguez-Blanco I, Toribio J: Ulcerated dermatofibroma with osteoclast-like giant cells. J Cutan Pathol; 2009 Oct;36 Suppl 1:16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ulcerated dermatofibroma with osteoclast-like giant cells.
  • METHODS: We report the clinical, histopathological and immunohistochemical findings of a 38-year-old man with an ulcerated dermatofibroma (DF) on the sole containing OLGC.
  • COMMENTS: DF, or cutaneous fibrous histiocytoma, is a frequent dermatological lesion with many clinicopathological variants.
  • [MeSH-major] Foot Diseases / pathology. Foot Ulcer / pathology. Giant Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19775390.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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10. Garrido-Ruiz MC, Carrillo R, Enguita AB, Peralto JL: Signet-ring cell dermatofibroma. Am J Dermatopathol; 2009 Feb;31(1):84-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Signet-ring cell dermatofibroma.
  • Dermatofibroma or cutaneous fibrous histiocytoma is a common benign skin lesion with multiple, distinct histologic variants, including cellular, aneurismal, epithelioid, atypical, lipidized "ankle-type," palisading, and cholesterotic.
  • Although dermatofibromas are considered benign neoplasms, certain variants including cellular and aneurismal ones have shown to have a notable tendency to locally recur after excision.
  • The finding of signet-ring cells in a skin neoplasm always raises the suspicion of metastatic adenocarcinoma, although a number of reports have shown their occurrence in primitive cutaneous neoplasms as well.
  • Signet-ring cell formation, however, has never been described in dermatofibroma.
  • We present, for the first time, a new, distinctive variant of dermatofibroma, so-called signet-ring cell dermatofibroma, in a 16-year-old man with a slowly growing skin tumor on the lateral side of his right leg.
  • Histochemical and immunohistochemical stainings confirmed the diagnosis of dermatofibroma.
  • The phenomenon described in this case enlarges the histologic spectrum of cutaneous fibrous histiocytoma and may cause substantial differential diagnostic problems.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19155733.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Tran TA, Hayner-Buchan A, Jones DM, McRorie D, Carlson JA: Cutaneous balloon cell dermatofibroma (fibrous histiocytoma). Am J Dermatopathol; 2007 Apr;29(2):197-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous balloon cell dermatofibroma (fibrous histiocytoma).
  • Dermatofibroma (DF) or cutaneous fibrous histiocytoma is a common benign skin tumor that exhibits multiple, distinct histologic variants.
  • Excisional biopsy revealed a circumscribed fibrous tumor populated by mostly clear and spindle cells.
  • [MeSH-major] Heel. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17414448.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; EC 2.3.2.13 / Factor XIIIa; EC 3.4.24.11 / Neprilysin
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12. Arpaia N, Cassano N, Vena GA: Dermoscopic patterns of dermatofibroma. Dermatol Surg; 2005 Oct;31(10):1336-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopic patterns of dermatofibroma.
  • BACKGROUND: Clinical and dermoscopic aspects of dermatofibroma (DF) are usually typical.
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 16188191.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Kasper B, Ouali M, Van Glabbeke M, Blay J, Bramwell VH, Woll PJ, Schöffski P: Prognostic factors in adolescents and young adults (AYA) with high-risk soft tissue sarcoma (STS) treated by adjuvant chemotherapy: A study based on two pooled European Organisation for Research and Treatment of Cancer (EORTC) clinical trials. J Clin Oncol; 2009 May 20;27(15_suppl):10573

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The variables of the multivariate analysis were gender, subtype and grade, tumor size and localization (limb vs. other), absence or presence of local recurrence and treatment (control arm vs. adjuvant chemotherapy).
  • RESULTS: Patients' characteristics were globally similar with two exceptions, histological subtype (p = 0.0043) and tumor size (p < .0001).
  • The commonest sarcoma subtype in the AYA population was synovial sarcoma (29 %), whereas leiomyosarcoma (18 %), malignant fibrous histiocytoma (MFH, 16 %) and liposarcoma (15 %) were more frequent in patients ≥ 30 years.
  • For OS, independent favorable prognostic factors were low grade and small tumor size for both groups; radical resection and MFH or liposarcoma subtype were factors of favorable prognosis for patients ≥ 30 years only.

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  • (PMID = 27963782.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Moreno-Vega A, Chavarría N, Rubio J, Villandiego I, Estepa R, Gordon M, Salvador J, Jimenez E: Primary breast sarcoma: Clinical and retrospective analysis of cases from Jerez General Hospital, Spain. J Clin Oncol; 2009 May 20;27(15_suppl):e21526

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We analysed diseases outcomes (disease free survival, DFS) by histology high risk factors (tumor size, histology, and proliferation index).
  • RESULTS: Seven cases of PBS (1 male/6 female) were reviewed, from 790 BC diagnosed (0.8%): 2 angiosarcomas (AS), 1 malignant fibrous histiocytoma, 2 undifferentiated, one osteoclastic and other spindle-cell sarcoma.

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  • (PMID = 27963456.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Gu M, Sohn K, Kim D, Kim B: Metastasizing dermatofibroma in lung. Ann Diagn Pathol; 2007 Feb;11(1):64-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasizing dermatofibroma in lung.
  • Benign dermatofibroma is very common skin tumor and can very rarely metastasize.
  • We report a case of metastasizing dermatofibroma on a 36-year-old woman who presented multiple bilateral lung nodules.
  • She underwent incisional biopsy for cellular dermatofibroma of the right shoulder 7 years ago.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 17240311.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; EC 3.4.24.11 / Neprilysin
  • [Number-of-references] 7
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16. Sachdev R, Sundram U: Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa. J Cutan Pathol; 2006 May;33(5):353-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa.
  • BACKGROUND: Distinction between cellular fibrous histiocytomas (FHs) with a deep component and dermatofibrosarcoma protuberans (DFSPs) can pose diagnostic problems.
  • Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa.
  • [MeSH-major] Antigens, CD / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. Biomarkers, Tumor / analysis. Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Receptors, Cell Surface / biosynthesis. Skin Neoplasms / diagnosis

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  • (PMID = 16640542.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD163 antigen; 0 / CD68 antigen, human; 0 / Receptors, Cell Surface; EC 2.3.2.13 / Factor XIIIa
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17. Rognstad ØB, Haas N, Sterry W, Astner S: Multiple clustered dermatofibroma with overlying sebaceous hyperplasia. J Dtsch Dermatol Ges; 2009 Nov;7(11):962-4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple clustered dermatofibroma with overlying sebaceous hyperplasia.
  • Multiple clustered dermatofibroma is a very rare clinical variant of the dermatofibroma, and sebaceous differentiation overlying dermatofibromas is also unusual.
  • We report the first case of a multiple clustered dermatofibroma with overlying sebaceous hyperplasia.
  • [MeSH-major] Histiocytoma, Benign Fibrous / complications. Histiocytoma, Benign Fibrous / pathology. Neoplasms, Multiple Primary / complications. Neoplasms, Multiple Primary / pathology. Sebaceous Gland Diseases / complications. Sebaceous Gland Diseases / pathology. Skin Neoplasms / pathology

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  • (PMID = 19538483.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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18. Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M: High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors. Arch Pathol Lab Med; 2006 Jun;130(6):831-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors.
  • CONTEXT: Dermatofibroma is a benign fibrohistiocytic tumor composed of a mixture of fibroblastic and histiocytic cells.
  • Deep penetrating dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans, and pseudosarcomatous dermatofibroma and dermatofibroma with monster giant cells share morphologic similarities with malignant fibrous histiocytoma and atypical fibroxanthoma.
  • DESIGN: We evaluated the immunophenotypic characteristics of 83 fibrohistiocytic tumors (36 typical dermatofibromas, 16 cases of dermatofibrosarcoma protuberans, 16 malignant fibrous histiocytomas, and 15 atypical fibroxanthomas) using antibodies against MIB-1 (Ki-67), factor XIIIa, CD34 (HPCA-1), HHF35 (muscle-specific actin), 1A4 (smooth muscle actin), cytokeratin (AE1/AE3, CAM 5.2, and 34betaE12), S100 protein, and desmin.
  • RESULTS: A high proliferative index detected by MIB-1 staining excluded the possibility of dermatofibroma and was diagnostically useful in separating this entity from dermatofibrosarcoma protuberans, malignant fibrous histiocytoma, and atypical fibroxanthoma.
  • A low proliferative index, however, could not differentiate dermatofibroma from dermatofibrosarcoma protuberans.
  • Factor XIIIa reactivity was not helpful for the diagnosis of dermatofibroma, whereas CD34 reactivity was statistically significant in the diagnosis of dermatofibrosarcoma protuberans.
  • CONCLUSION: Evaluation of the proliferative index may further assist in distinguishing dermatofibroma from dermatofibrosarcoma protuberans, atypical fibroxanthoma, and malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Ki-67 Antigen / metabolism. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Biopsy. Cell Nucleus / metabolism. Cell Nucleus / pathology. Cell Proliferation. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Fluorescent Antibody Technique, Indirect. Histiocytoma, Malignant Fibrous / pathology. Humans. Immunoenzyme Techniques. Xanthomatosis / pathology

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  • [CommentIn] Arch Pathol Lab Med. 2008 Feb;132(2):160; author reply 160-1 [18251566.001]
  • (PMID = 16740036.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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19. Curcó N, Pagerols X, García M, Tarroch X, Vives P: Atrophic dermatofibroma accompanied by aneurysmatic characteristics. J Eur Acad Dermatol Venereol; 2006 Mar;20(3):331-3
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  • [Title] Atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • The lesion diagnosed as an anetoderma was excised and the biopsy showed an atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • [MeSH-major] Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16503899.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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20. Spaun E, Zelger B: Dermatofibroma with intracytoplasmic eosinophilic globules: an unusual phenomenon. J Cutan Pathol; 2009 Jul;36(7):796-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma with intracytoplasmic eosinophilic globules: an unusual phenomenon.
  • Dermatofibroma (DF) is a very common lesion of the skin and presents in many guises that might cause problems in differential diagnosis.
  • [MeSH-major] Cytoplasmic Granules / pathology. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology

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  • [Copyright] (c) 2009 John Wiley & Sons A/S.
  • (PMID = 19519612.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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21. Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J, Puig S: Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients. Br J Dermatol; 2006 Feb;154(2):244-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients.
  • BACKGROUND: The clinical diagnosis of dermatofibroma is commonly easy.
  • However, the differentiation of dermatofibroma from other cutaneous tumours is difficult in some instances, primarily in atypical cases and rare variants.
  • Haemosiderotic dermatofibroma is a variant composed of numerous small vessels, extravasated erythrocytes and intra- and extracellular haemosiderin deposits.
  • Aneurysmal dermatofibroma is a variant composed of large, blood-filled spaces without endothelial lining.
  • Some authors consider that haemosiderotic dermatofibroma is an early stage in the development of aneurysmal dermatofibroma.
  • The clinical differential diagnosis of haemosiderotic or aneurysmal dermatofibroma must include melanoma and other melanocytic tumours, vascular neoplasms, adnexal tumours and nonspecific cysts.
  • CONCLUSIONS: This dermoscopic pattern yielded the diagnosis of haemosiderotic or aneurysmal dermatofibroma in most cases.
  • However, this multicomponent pattern may present in some melanomas and although it is useful in determining a clinical diagnosis of aneurysmal dermatofibroma, it may not be specific to this entity.
  • [MeSH-major] Dermoscopy. Hemosiderin / analysis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • [CommentIn] Br J Dermatol. 2007 Jan;156(1):199-200 [17199605.001]
  • (PMID = 16433792.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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22. Shuweiter M, Böer A: Spectrum of follicular and sebaceous differentiation induced by dermatofibroma. Am J Dermatopathol; 2009 Dec;31(8):778-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spectrum of follicular and sebaceous differentiation induced by dermatofibroma.
  • BACKGROUND: The term "induction" has been used to designate epidermal changes above dermatofibroma.
  • Whereas follicular differentiation has been reported frequently, sebaceous hyperplasia above dermatofibroma is considered a rarity.
  • OBJECTIVE: To characterize all changes overlying dermatofibroma and to determine their frequency.
  • METHODS: Sections cut from 210 consecutive examples of dermatofibroma were stained with hematoxylin and eosin and analyzed for the presence or absence of induction, for the type of change induced, and for features associated with these findings.
  • [MeSH-major] Hair Follicle / pathology. Histiocytoma, Benign Fibrous / pathology. Sebaceous Glands / pathology. Skin Neoplasms / pathology

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  • (PMID = 19955877.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Davis TT, Calilao G, Fretzin D: Sebaceous hyperplasia overlying a dermatofibroma. Am J Dermatopathol; 2006 Apr;28(2):155-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous hyperplasia overlying a dermatofibroma.
  • The presence of sebaceous differentiation overlying a dermatofibroma is unusual.
  • We report two patients with sebaceous hyperplasia overlying a dermatofibroma and discuss possible mechanisms for induction of the epithelium and adnexa by the mesenchyme in a dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Sebaceous Glands / pathology. Skin Neoplasms / pathology

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  • (PMID = 16625080.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
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24. Adler N, Tsabari C, Sulkes J, Ad-El D, Feinmesser M: Cyclooxygenase-2 expression in dermatofibroma and dermatofibrosarcoma protuberans. J Cutan Pathol; 2008 Jun;35(6):532-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cyclooxygenase-2 expression in dermatofibroma and dermatofibrosarcoma protuberans.
  • BACKGROUND: Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) occasionally resemble each other histologically but differ in histogenesis and biological behavior.
  • [MeSH-major] Cyclooxygenase 2 / metabolism. Dermatofibrosarcoma / enzymology. Histiocytoma, Benign Fibrous / enzymology. Skin Neoplasms / enzymology

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  • (PMID = 18201240.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 1.14.99.1 / Cyclooxygenase 2
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25. Agero AL, Taliercio S, Dusza SW, Salaro C, Chu P, Marghoob AA: Conventional and polarized dermoscopy features of dermatofibroma. Arch Dermatol; 2006 Nov;142(11):1431-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conventional and polarized dermoscopy features of dermatofibroma.
  • These new criteria can aid in the diagnosis of dermatofibroma.
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17116833.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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26. González-Vela MC, Val-Bernal JF, Martino M, González-López MA, García-Alberdi E, Hermana S: Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma. Histol Histopathol; 2005 07;20(3):801-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma.
  • Dermatofibroma (DF) is a common benign cutaneous tumor with many variants based on alterations in the morphology and composition of its diverse elements.
  • [MeSH-major] Fibroma / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15944929.001).
  • [ISSN] 0213-3911
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, CD99; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Vimentin
  • [Number-of-references] 21
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27. de Feraudy S, Mar N, McCalmont TH: Evaluation of CD10 and procollagen 1 expression in atypical fibroxanthoma and dermatofibroma. Am J Surg Pathol; 2008 Aug;32(8):1111-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of CD10 and procollagen 1 expression in atypical fibroxanthoma and dermatofibroma.
  • Atypical fibroxanthoma (AFX) (dermal pleomorphic sarcoma) remains a somewhat controversial entity.
  • Group 2 consisted of a direct comparison of 11 AFX, 11 dermatofibroma (DF), and 7 epithelioid dermatofibroma (EDF) using the CD10 reagent on cases identified by database search.
  • Not surprisingly, CD10 expression is also common in DF, a benign analog of AFX, with the exception of its epithelioid variant.
  • [MeSH-major] Collagen Type I / analysis. Histiocytoma, Benign Fibrous / pathology. Neprilysin / analysis. Procollagen / analysis. Sarcoma / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology

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  • (PMID = 18545147.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Collagen Type I; 0 / Procollagen; 0 / S100 Proteins; 68238-35-7 / Keratins; EC 3.4.24.11 / Neprilysin
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28. Hamel J, Burgdorf WH, Bräuninger W: The man behind the eponym: Hans Biberstein and follicular hyperplasia overlying dermatofibroma. Am J Dermatopathol; 2009 Oct;31(7):710-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The man behind the eponym: Hans Biberstein and follicular hyperplasia overlying dermatofibroma.
  • After a hiatus of 30 years, the dermatopathologic literature once again began addressing his seminal finding but never gave him proper credit.
  • We suggest Biberstein's sign as an appropriate term for basaloid follicular hyperplasia overlying a dermatofibroma and as a small tribute to a pioneer dermatopathologist.
  • [MeSH-major] Dermatology / history. Histiocytoma, Benign Fibrous / history. Histiocytoma, Benign Fibrous / pathology. Pathology / history

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  • (PMID = 19633531.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article
  • [Publication-country] United States
  • [Personal-name-as-subject] Biberstein H
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29. Ozdemir F, Kilinc I, Akalin T: Homogeneous blue pigmentation in dermatofibroma simulating a blue naevus. J Eur Acad Dermatol Venereol; 2006 Jul;20(6):733-4
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  • [Title] Homogeneous blue pigmentation in dermatofibroma simulating a blue naevus.
  • A case with a pigmented skin lesion that was diagnosed as a blue naevus on clinical and dermoscopic grounds and histopathologically confirmed as a dermatofibroma is presented.
  • By means of this case, we define dermatofibroma as a new exception for 'homogeneous blue pigmentation' on dermoscopy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Nevus, Blue / pathology

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  • (PMID = 16836506.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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30. Pongpudpunth M, Keady M, Mahalingam M: Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis? J Cutan Pathol; 2009 Oct;36(10):1083-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis?
  • BACKGROUND: The etiopathogenesis of dermatofibroma (DF), a common benign fibrohistiocytic tumor, is debatable.
  • [MeSH-major] Elastic Tissue / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19615002.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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31. Amico P, Vecchio GM, Bisceglia M, Vasquez E, Magro G: Atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component. Histogenetic considerations in the wide spectrum of fibrohistiocytic dermal tumours. Pathologica; 2010 Jun;102(3):115-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component. Histogenetic considerations in the wide spectrum of fibrohistiocytic dermal tumours.
  • Atypical and epithelioid cell variants of dermatofibroma may represent a potential diagnostic pitfall.
  • Only rarely atypical dermatofibroma may show focal epithelioid cell features.
  • We herein report a rare case of dermatofibroma composed of a predominant (> 90%) epithelioid/deciduoid-like cell component, in which rare multinucleated bizarre cells and atypical mitoses were additional findings.
  • Tumour was classified as "atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component".
  • The coexistence of at least two different variants, i.e. epithelioid and atypical variants, in the same dermatofibroma suggests that dermal fibrohistiocytic tumours belong to a continuous morphological spectrum.
  • Accordingly, the morphological variants of dermatofibroma should be regarded as variations on a common basic theme.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Malignant Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 21171517.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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32. Mori T, Misago N, Yamamoto O, Toda S, Narisawa Y: Expression of nestin in dermatofibrosarcoma protuberans in comparison to dermatofibroma. J Dermatol; 2008 Jul;35(7):419-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of nestin in dermatofibrosarcoma protuberans in comparison to dermatofibroma.
  • Making a differential diagnosis to distinguish dermatofibrosarcoma protuberans (DFSP) from dermatofibroma (DF) is occasionally difficult.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Intermediate Filament Proteins / metabolism. Nerve Tissue Proteins / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 18705829.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin
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33. Chaâbouni S, Ayadi L, Masmoudi A, Dhouib M, Méziou J, Dammak A, Charfi S, Gouiaa N, Turki H, Abdelmoula M, Boudawara T: [Retroauricular dermatofibroma in a child simulating a malignant tumour]. Arch Pediatr; 2008 Mar;15(3):283-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Retroauricular dermatofibroma in a child simulating a malignant tumour].
  • BACKGROUND: Dermatofibroma represents one of the commonest benign soft tissue tumours, and its diagnosis is usually straightforward if classical clinicopathologic features are evident.
  • We report a peculiar case of an aggressive cellular dermatofibroma in a child that simulated a malignant tumour.
  • The lesion had the full microscopic characteristics of a cellular dermatofibroma.
  • CONCLUSION: Dermatofibroma is one of the major differential diagnosis of nodular cutaneous tumours in children that simulate malignancy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18325746.001).
  • [ISSN] 0929-693X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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34. Scalvenzi M, Balato A, De Natale F, Francia MG, Mignogna C, De Rosa G: Hemosiderotic dermatofibroma: report of one case. Dermatology; 2007;214(1):82-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemosiderotic dermatofibroma: report of one case.
  • Dermatofibroma (DF) is a common benign fibrohistiocytic lesion which presents with a wide variety of clinicopathological features.
  • [MeSH-major] Hemosiderosis / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Dermoscopy. Diagnosis, Differential. Disease Progression. Humans. Male

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  • (PMID = 17191053.001).
  • [ISSN] 1018-8665
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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35. Leow LJ, Sinclair PA, Horton JJ: Plaque-like dermatofibroma: A distinct and rare benign neoplasm? Australas J Dermatol; 2008 May;49(2):106-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plaque-like dermatofibroma: A distinct and rare benign neoplasm?
  • Dermoscopic examination showed diffuse homogenous pigmentation in the absence of other diagnostic criteria for dermatofibroma.
  • Based on the histological findings, a diagnosis of dermatofibroma was made for each of these cases.
  • Fewer than 20 adult cases of large dermatofibroma of this scale, designated giant dermatofibroma, have been reported to date; and only two have shown a plaque-like appearance, the remainder being pedunculated.
  • The authors propose plaque-like dermatofibroma as a variety of large dermatofibroma distinct to pedunculated giant dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin / pathology. Skin Neoplasms / pathology

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  • (PMID = 18412813.001).
  • [ISSN] 1440-0960
  • [Journal-full-title] The Australasian journal of dermatology
  • [ISO-abbreviation] Australas. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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36. Rhee DY, Lee HW, Chung WK, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK: Giant dermatofibroma with granular cell changes: side-effect of bee-venom acupuncture? Clin Exp Dermatol; 2009 Jul;34(5):e18-20
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  • [Title] Giant dermatofibroma with granular cell changes: side-effect of bee-venom acupuncture?
  • Dermatofibroma (DF) is a common benign fibrohistiocytic tumour with a predilection for the legs in middle-aged women.
  • [MeSH-major] Acupuncture Therapy / adverse effects. Bee Venoms / adverse effects. Histiocytoma, Benign Fibrous / etiology. Skin Neoplasms / etiology

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  • (PMID = 19486038.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bee Venoms
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37. Dominguez-Malagon H, Valdez-Carrillo Mdel C, Cano-Valdez AM: Dermatofibroma and dermatofibrosarcoma protuberans: a comparative ultrastructural study. Ultrastruct Pathol; 2006 Jul-Aug;30(4):283-91
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  • [Title] Dermatofibroma and dermatofibrosarcoma protuberans: a comparative ultrastructural study.
  • Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are dermal tumors whose histogenesis has not been well defined to date.
  • Another common finding was the presence of multivesicular buds (MVB), peculiar structures that contain microvesicles abutting from the cell membrane.
  • [MeSH-major] Dermatofibrosarcoma / ultrastructure. Histiocytoma, Benign Fibrous / ultrastructure. Skin Neoplasms / ultrastructure

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  • (PMID = 16971353.001).
  • [ISSN] 1521-0758
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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38. Gonzalez S: Apocrine gland cyst with hemosiderotic dermatofibroma-like stroma: report of two cases. Am J Dermatopathol; 2005 Feb;27(1):36-8
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  • [Title] Apocrine gland cyst with hemosiderotic dermatofibroma-like stroma: report of two cases.
  • Two cases of an unusual cutaneous lesion characterized by a dermal nodule with apocrine gland cysts surrounded by a hemosiderotic dermatofibroma-like proliferating stroma are reported.
  • The cystic spaces consisted of ductal structures and a bilayered epithelial covering with apocrine differentiation; the surrounding area showed a stroma composed of a mixture of both fibrocytes and macrophages and abundant hemosiderin granules; foci of recent hemorrhages and a more dense fibrous stroma at the periphery with typical storiform areas were also visible.
  • Both cases have shown a benign course without local recurrence in follow up until this report date.
  • [MeSH-major] Apocrine Glands / pathology. Epidermal Cyst / pathology. Hemosiderin / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15677975.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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39. Gershtenson PC, Krunic AL, Chen HM: Multiple clustered dermatofibroma: case report and review of the literature. J Cutan Pathol; 2010 Sep;37(9):e42-5
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  • [Title] Multiple clustered dermatofibroma: case report and review of the literature.
  • Multiple clustered dermatofibroma (MCDF) is a distinct entity with only 12 reported cases in the literature.
  • On histology, MCDF is consistent with benign dermatofibromas.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19614987.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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40. Yamamoto T: Dermatofibroma: a possible model of local fibrosis with epithelial/mesenchymal cell interaction. J Eur Acad Dermatol Venereol; 2009 Apr;23(4):371-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma: a possible model of local fibrosis with epithelial/mesenchymal cell interaction.
  • Dermatofibromas are benign dermal nodules usually seen on the extremities; however, whether a dermatofibroma is a reactive fibrous hyperplasia or a true neoplasm is still unclear.
  • Fibrous type dermatofibromas might be regarded as the symptom of local fibrotic processes and thus present a possible model of local fibrosis.
  • Interaction between proliferated dermatofibroma fibroblasts and overlying elongated epidermis suggests a relationship between keratinocytes and mesenchymal cells.
  • [MeSH-major] Epithelial Cells / pathology. Fibrosis / pathology. Histiocytoma, Benign Fibrous / pathology. Mesoderm / pathology. Models, Biological

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  • (PMID = 19175704.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 54
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41. Kuroda K, Tajima S: Proliferation of HSP47-positive skin fibroblasts in dermatofibroma. J Cutan Pathol; 2008 Jan;35(1):21-6
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  • [Title] Proliferation of HSP47-positive skin fibroblasts in dermatofibroma.
  • BACKGROUND: The cell origin of dermatofibroma (DF) has not been clarified satisfactorily.
  • [MeSH-major] Fibroblasts / metabolism. HSP47 Heat-Shock Proteins / metabolism. Histiocytoma, Benign Fibrous / metabolism. Skin / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 18095990.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD68 antigen, human; 0 / HSP47 Heat-Shock Proteins; 0 / SERPINH1 protein, human; EC 2.3.2.13 / Factor XIIIa
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42. Song Y, Sakamoto F, Ito M: Characterization of factor XIIIa+ dendritic cells in dermatofibroma: Immunohistochemical, electron and immunoelectron microscopical observations. J Dermatol Sci; 2005 Aug;39(2):89-96
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  • [Title] Characterization of factor XIIIa+ dendritic cells in dermatofibroma: Immunohistochemical, electron and immunoelectron microscopical observations.
  • OBJECTIVES: In this study, we examined the fine structures and potential heterogeneity among the subgroup of factor XIIIa (FXIIIa) positive dendritic cells consisted of eleven cases of dermatofibroma (DF).
  • [MeSH-major] Dendritic Cells / metabolism. Factor XIIIa / biosynthesis. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 16055004.001).
  • [ISSN] 0923-1811
  • [Journal-full-title] Journal of dermatological science
  • [ISO-abbreviation] J. Dermatol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; EC 2.3.2.13 / Factor XIIIa
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43. Kovach BT, Boyd AS: Melanoma associated with a dermatofibroma. J Cutan Pathol; 2007 May;34(5):420-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanoma associated with a dermatofibroma.
  • BACKGROUND: Dermatofibromas are common benign cutaneous fibrohistiocytic neoplasms, whereas melanomas are potentially aggressive malignancies.
  • The atypical melanocytes stained for MART-1 and S-100, whereas the underlying fibrohistiocytic tumor took up factor XIIIa immunostain, confirming the diagnosis of invasive malignant melanoma occurring in association with a dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17448199.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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44. Lee HI, Lee JW, Han TY, Li K, Hong CK, Seo SJ, Song KY: A case of dermatofibroma of the upper lip. Ann Dermatol; 2010 Aug;22(3):333-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of dermatofibroma of the upper lip.
  • Dermatofibroma (DF) is a common benign mesenchymal tumor composed of fibroblastic and histiocytic cells.

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  • [Cites] Am J Dermatopathol. 1997 Apr;19(2):147-53 [9129699.001]
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  • (PMID = 20711274.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2917691
  • [Keywords] NOTNLM ; Dermatofibroma / Lip
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45. Quigley BC, Ricciuti J, Morgan MB: Amyloid light chain deposition associated with dermatofibroma: serendipity or association? Am J Dermatopathol; 2010 May;32(3):298-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amyloid light chain deposition associated with dermatofibroma: serendipity or association?
  • In contrast, secondary cutaneous amyloidosis is related to lesions such as squamous cell carcinoma, Bowen disease, basal cell carcinoma, and discoid lupus erythematosus, and has been shown in most cases to be derived from keratin epithelial elements.
  • Herein, we present a unique case of nodular amyloidosis occurring in association with a cellular dermatofibroma.
  • [MeSH-major] Amyloid / metabolism. Histiocytoma, Benign Fibrous / pathology. Immunoglobulin Light Chains / metabolism. Skin Neoplasms / pathology

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  • (PMID = 20110798.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid; 0 / Immunoglobulin Light Chains
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46. Papalas JA, Balmer NN, Wallace C, Sangüeza OP: Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review. Am J Dermatopathol; 2009 Jun;31(4):379-83
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  • [Title] Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review.
  • Ossifying dermatofibroma with osteoclast-like giant cells is an uncommon variant that has only rarely been reported.
  • We report another case of ossifying dermatofibroma with osteoclast-like giant cells and describe the immunohistochemical expression pattern of these rare lesions.
  • Large islands of spindled cells arranged in a storiform pattern were separated by broad fibrous bands.
  • [MeSH-major] Giant Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Ossification, Heterotopic / pathology. Osteoclasts / pathology. Skin Neoplasms / pathology

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  • (PMID = 19461244.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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47. Hancox JG, Kelley B, Greenway HT Jr: Treatment of dermatofibroma sarcoma protuberans using modified Mohs micrographic surgery: no recurrences and smaller defects. Dermatol Surg; 2008 Jun;34(6):780-4
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  • [Title] Treatment of dermatofibroma sarcoma protuberans using modified Mohs micrographic surgery: no recurrences and smaller defects.
  • OBJECTIVES: The purpose of this study was to evaluate the use of modified Mohs micrographic surgery (MMS) for dermatofibroma sarcoma protuberans (DFSP) in a single institution by a single surgeon.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Cohort Studies. Disease-Free Survival. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18318720.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Kim HJ, Lee JY, Kim SH, Seo YJ, Lee JH, Park JK, Kim MH, Cinn YW, Cho KH, Yoon TY: Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34. Br J Dermatol; 2007 Aug;157(2):319-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34.
  • BACKGROUND: The distinction between dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) is a well-known challenge for dermatopathologists.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Matrix Metalloproteinase 11 / metabolism

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  • (PMID = 17596171.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Multicenter Study; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; EC 2.3.2.13 / Factor XIIIa; EC 3.4.24.- / Matrix Metalloproteinase 11
  • [Number-of-references] 24
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49. Wang SQ, Lee PK: Treatment of dermatofibroma with a 600 nm pulsed dye laser. Dermatol Surg; 2006 Apr;32(4):532-5
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  • [Title] Treatment of dermatofibroma with a 600 nm pulsed dye laser.
  • BACKGROUND: Dermatofibroma (DF) is one of the most basic and common dermatologic diseases treated by practicing dermatologists on a daily basis.
  • Although benign, it can be pruritic or tender.
  • [MeSH-major] Histiocytoma, Benign Fibrous / therapy. Laser Therapy

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  • (PMID = 16681661.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Kubo M, Ihn H, Yamane K, Tamaki K: The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans. Br J Dermatol; 2006 May;154(5):919-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans.
  • BACKGROUND: Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are benign and intermediate malignant fibrotic dermal tumours, respectively.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Neoplasm Proteins / metabolism. Receptors, Transforming Growth Factor beta / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 16634896.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / Receptors, Transforming Growth Factor beta; EC 2.7.1.11 / TGF-beta type I receptor; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / Activin Receptors, Type I; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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51. Labonte S, Hanna W, Bandarchi-Chamkhaleh B: A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma. J Cutan Pathol; 2007 Nov;34(11):857-60
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  • [Title] A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma.
  • Cellular dermatofibroma (CDF) can mimic DFSP, but typical cases are easily differentiated from DFSP by their staining pattern for CD34 and factor 13a.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Proto-Oncogene Proteins c-kit / biosynthesis. Skin Neoplasms / metabolism

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  • (PMID = 17944726.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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52. Fernandez-Flores A, Manjon JA: Mitosis in dermatofibroma: a worrisome histopathologic sign that does not necessarily equal recurrence. J Cutan Pathol; 2008 Sep;35(9):839-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitosis in dermatofibroma: a worrisome histopathologic sign that does not necessarily equal recurrence.
  • BACKGROUND: High mitotic rate is a worrying histopathologic feature that pathologists occasionally face when diagnosing benign fibrous histiocytoma (BFH), that otherwise seem to be benign.
  • The clinical significance of this histologic feature has not been completely studied, because no studies on large series of BFH have been carried out, concerning mitotic rate as the only worrisome morphologic sign, in relation with recurrence.
  • CONCLUSIONS: We conclude that common BFH can occasionally present a high mitotic rate and still show a benign behavior.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Mitosis. Neoplasm Recurrence, Local. Skin Neoplasms / pathology

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  • (PMID = 18331566.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MIB-1 antibody
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53. Yamamoto T, Sumi K, Yokozeki H, Nishioka K: Multiple cutaneous fibrous histiocytomas in association with systemic lupus erythematosus. J Dermatol; 2005 Aug;32(8):645-9
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  • [Title] Multiple cutaneous fibrous histiocytomas in association with systemic lupus erythematosus.
  • Cutaneous fibrous histiocytomas are usually regarded as superficial lesions and commonly known as dermatofibromas; however, unusual cases histologically showing fibrohistiocytic proliferation extending into the deeper dermis or subcutaneous tissues are occasionally experienced.
  • Some authors propose this type as benign fibrous histiocytoma of the skin, distinct from dermatofibroma.
  • The nodule on the forehead did not present a typical clinical appearance of dermatofibroma, and histopathological examination showed fibrohistiocytic proliferation with a storiform pattern extending into the deep dermis and subcutaneous tissues.
  • By contrast, histology of the nodule on the abdomen showed fibrohistiocytic proliferation confined to the dermis and compatible with dermatofibroma.
  • Although multiple dermatofibromas are occasionally seen in patients with SLE, benign fibrous histiocytoma of the skin showing deeper invasion than dermatofibroma is rarely associated with SLE.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Lupus Erythematosus, Systemic. Skin Neoplasms / diagnosis


54. Kideryová L, Lacina L, Dvoránková B, Stork J, Cada Z, Szabo P, André S, Kaltner H, Gabius HJ, Smetana K Jr: Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts. J Dermatol Sci; 2009 Jul;55(1):18-26
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  • [Title] Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts.
  • BACKGROUND: Benign and malignant fibrous histiocytoma present with a considerable difference concerning cellular organization in their vicinity.
  • OBJECTIVE: Normally appearing epithelium covers the malignant form in contrast to hyperplastic epidermis for benign tumors.
  • METHODS: Fibroblasts were isolated from benign and malignant fibrous histiocytomas, respectively, and also from normal dermis.
  • Cells prepared from benign fibrous histiocytoma were capable to effect strong expression of keratin 19 and production of a galectin-1-rich extracellular matrix.
  • Fibroblasts isolated from malignant fibrous histiocytoma led to a phenotype very similar to that when keratinocytes were cocultured with normal dermal fibroblasts.
  • CONCLUSION: Fibroblasts prepared from benign fibrous histiocytoma were biologically active on keratinocytes in a particular manner.
  • Our results on fibroblast activity are suggested to be relevant for morphologic differences observed in vivo between normal epidermis and epidermis adjacent to the studied tumor types.
  • [MeSH-major] Fibroblasts / pathology. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Malignant Fibrous / pathology. Keratinocytes / pathology. Skin Neoplasms / pathology

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  • (PMID = 19414239.001).
  • [ISSN] 1873-569X
  • [Journal-full-title] Journal of dermatological science
  • [ISO-abbreviation] J. Dermatol. Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Galectin 1; 0 / Keratin-19
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55. Shin JW, Park HS, Kim BK, Kim YA, Kim MG, Won CH, Cho S: Aneurysmal benign fibrous histiocytoma with atrophic features. Ann Dermatol; 2009 Feb;21(1):42-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aneurysmal benign fibrous histiocytoma with atrophic features.
  • Aneurysmal benign fibrous histiocytoma is an uncommon pathologic variant of dermatofibroma.
  • In addition to the features of a typical dermatofibroma, it has large cleft-like or cavernous blood-filled spaces with numerous hemosiderin pigments.
  • It should be differentiated from angiomatoid malignant fibrous histiocytoma, malignant melanoma, and vascular tumors such as Kaposi's sarcoma and angiosarcoma.
  • Atrophic dermatofibroma is also a rare variant of dermatofibroma, and the combination of aneurysmal and atrophic features is rarer still.
  • We report a case of aneurysmal benign fibrous histiocytoma with atrophic features in a 27-year-old male who had a grayish-brown atrophic patchy lesion on his back for 2 years.

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  • [Cites] J Am Acad Dermatol. 1991 Dec;25(6 Pt 1):1081-2 [1810988.001]
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  • (PMID = 20548854.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2883367
  • [Keywords] NOTNLM ; Aneurysmal variant / Atrophy / Dermatofibroma
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56. Gencoglan G, Karaarslan IK, Dereli T, Kazandi AC: Dermatofibroma on the palmar surface of the hand. Skinmed; 2008 Jan-Feb;7(1):41-3
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  • [Title] Dermatofibroma on the palmar surface of the hand.
  • Clinically, the nodular lesion appeared to be a benign tumor (Figure C).

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  • (PMID = 18174803.001).
  • [ISSN] 1540-9740
  • [Journal-full-title] Skinmed
  • [ISO-abbreviation] Skinmed
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Garrido-Ruiz MC, Ramos P, Enguita AB, Rodriguez Peralto JL: Subcutaneous atypical fibrous histiocytoma. Am J Dermatopathol; 2009 Jul;31(5):499-501

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  • [Title] Subcutaneous atypical fibrous histiocytoma.
  • Benign fibrous histiocytoma is one of the most frequent benign neoplasms mainly composed of a mixture of fibroblastic and histiocytic cells, especially found in the skin (dermatofibroma), particularly in the limbs.
  • The diagnosis of cutaneous benign fibrous histiocytoma is generally easy; however, rare variants may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination.
  • Thus, deep subcutaneous dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans and dermatofibroma with monster giant cells from malignant fibrous histiocytoma and atypical fibroxanthoma.
  • We report a case of a 38-year-old woman with a painless swelling on the abdominal wall, which was totally excised and histopathologically diagnosed as subcutaneous atypical fibrous histiocytoma.
  • Recognition of dermatofibroma is important, allowing sequential excision and optimal results.
  • To the best of our knowledge, we report the first case of subcutaneous fibrous histiocytoma with monster cells.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19542931.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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58. Kohlhof JK, Müller-Richter U, Driemel O, Sachs H: [Pleomorphic malignant fibrous histiocytoma of the periorbital region]. Klin Monbl Augenheilkd; 2007 Mar;224(3):203-6
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  • [Title] [Pleomorphic malignant fibrous histiocytoma of the periorbital region].
  • [Transliterated title] Pleomorphes malignes fibröses Histiozytom der Periorbitalregion.
  • BACKGROUND: Pleomorphic malignant fibrous histiocytomas (undifferentiated pleomorphic sarcomas) belong to the soft tissue tumours and are more likely in elder patients.
  • About 3 % percent of all pleomorphic malignant fibrous histiocytomas arise in the head and neck region.
  • 30 % of these histiocytomas develop in the paranasal sinuses.
  • A biopsy was classified as a malignant fibrous tumour with the subclassification of an atypical fibroxanthoma.
  • Therefore the tumour classification was changed to pleomorphic malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma).
  • In the process of finding the right diagnosis sometimes a change from benign to malignant occurs and alters the treatment regime.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / radiography. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography

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  • (PMID = 17385123.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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59. Khalkhali K, Azizi MR, Atighechi S: A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland. Arch Iran Med; 2007 Jan;10(1):100-3

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  • [Title] A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland.
  • The light microscopic and immunohistochemical characteristics of a case of fibrous histiocytoma of intermediate malignancy arising from the parotid gland are presented.
  • Histologic characteristics similar to those displayed by dermatofibroma and dermatofibrosarcoma protuberans help to differentiate this tumor from other spindle cell tumors.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17198464.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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60. Rudisaile SN, Hurt MA, Santa Cruz DJ: Granular cell atypical fibroxanthoma. J Cutan Pathol; 2005 Apr;32(4):314-7
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  • [Title] Granular cell atypical fibroxanthoma.
  • We report on two patients with granular cell atypical fibroxanthoma.
  • Immunohistochemical stains were positive for CD68 and vimentin and negative for Melan-A or human melanoma black (HMB)-45, S-100 protein, pancytokeratin, and actin, consistent with atypical fibroxanthoma.
  • These include the conventional granular cell tumor and its malignant form, leiomyoma, leiomyosarcoma, dermatofibroma, dermatofibrosarcoma protuberans, and angiosarcoma.
  • [MeSH-major] Granular Cell Tumor / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15769283.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 25
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61. Toyozawa S, Yamamoto Y, Ishida Y, Kondo T, Nakamura Y, Furukawa F: Immunohistochemical analysis of CXCR4 expression in fibrohistiocytic tumors. Acta Histochem Cytochem; 2010 May 1;43(2):45-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We analyzed the expression of CXCR4, CCR6 and CCR7 in fibrohistiocytic tumors, including dermatofibrosarcoma protuberance (DFSP), malignant fibrous histiocytoma (MFH), dermatofibroma (DF) using immunohistochemistry.

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  • [Cites] Int J Cancer. 2006 Nov 1;119(9):2026-9 [16671092.001]
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  • (PMID = 20514291.001).
  • [ISSN] 1347-5800
  • [Journal-full-title] Acta histochemica et cytochemica
  • [ISO-abbreviation] Acta Histochem Cytochem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC2875858
  • [Keywords] NOTNLM ; CXCR4 / DFSP / fibrohistiocytic tumors / immunohistochemistry
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62. King R, Googe PB, Page RN, Mihm MC Jr: Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ. Mod Pathol; 2005 Aug;18(8):1043-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A single case of lentiginous melanocytic hyperplasia overlying a dermatofibroma has been reported, however, nevi and melanoma have to the best of our knowledge, not been previously reported.
  • The clinical diagnosis ranged from dermatofibroma to desmoplastic melanoma.
  • In four cases the dermal component appeared to merge with the dermatofibroma.
  • In the case of the melanoma in situ, the dermatofibroma abutted the epidermis.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanocytes / pathology. Skin Neoplasms / pathology

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  • (PMID = 15803191.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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63. Kim J, McNiff JM: Keloidal atypical fibroxanthoma: a case series. J Cutan Pathol; 2009 May;36(5):535-9
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  • [Title] Keloidal atypical fibroxanthoma: a case series.
  • BACKGROUND: Keloidal atypical fibroxanthoma (AFX) is a rare variant of AFX with thick bands of hyalinized collagen.
  • The identification of keloidal collagen associated with fibrohistiocytic cells may erroneously lead to the diagnosis of keloidal dermatofibroma.
  • CONCLUSIONS: The diagnosis of keloidal AFX requires the exclusion of other malignant and benign lesions with keloidal or sclerotic collagen.
  • The finding of sclerotic collagen preferentially deposited around vessels is an interesting and poorly understood phenomenon.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Keloid / pathology

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  • (PMID = 19476521.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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64. Hügel H: [Fibrohistiocytic skin tumors]. J Dtsch Dermatol Ges; 2006 Jul;4(7):544-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • "Fibrohistiocytic" means in this context the morphologic similarity of the cells with fibroblasts and histiocytes.
  • The WHO classification of 2005 includes the following entities as fibrohistiocytic tumors of the skin: BENIGN: 1.
  • Fibrous histiocytoma (FH)/(synonymous: Dermatofibroma.
  • Variants of FH: 1a. cellular fibrous histiocytoma, 1b. atypical (pseudosarcomatous) fibrous histiocytoma, 1c. aneurysmatic fibrous histiocytoma, 1d. epithelioid fibrous histiocytoma; 2. dermatomyofibroma; 3. (juvenile) xanthogranuloma.
  • INTERMEDIATE: 4. plexiform fibrohistiocytic tumor; 5. dermatofibrosarcoma protuberans; 6. atypical Fibroxanthoma.
  • MALIGNANT: 7. malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / classification. Histiocytoma, Benign Fibrous / pathology. Leiomyoma / classification. Leiomyoma / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology

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  • (PMID = 16827912.001).
  • [ISSN] 1610-0379
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 53
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65. Ballester I, Betlloch I, Pérez-Crespo M, Toledo F, Cuesta L: Atypical presentation of an omphalomesenteric duct cyst. Dermatol Online J; 2009;15(6):13
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  • This report illustrates the possibility of OMD cyst resembling a keloid or dermatofibroma.

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  • (PMID = 19723487.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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66. Lin N, Urabe K, Moroi Y, Uchi H, Nakahara T, Dainichi T, Kokuba H, Tu Y, Furue M: Overexpression of phosphorylated-STAT3 and phosphorylated-ERK protein in dermatofibrosarcoma protuberans. Eur J Dermatol; 2006 May-Jun;16(3):262-5
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  • The expressions of p-STAT3 and p-ERK were analyzed by immunohistochemical staining in formalin-fixed, paraffin-embedded tissue sections of human DFSP and dermatofibroma.
  • Ten cases were positive for p-STAT3 expression in 14 cases of DFSP, however, only 5 cases were positive in 20 cases of dermatofibroma.
  • Eleven out of 14 cases of DFSP expressed p-ERK, but only four cases were positive in 20 cases of dermatofibroma.
  • The expressions of p-STAT3 and p-ERK were significantly higher than those in dermatofibroma (both p < 0.01).
  • [MeSH-major] Extracellular Signal-Regulated MAP Kinases / metabolism. Histiocytoma, Benign Fibrous / metabolism. STAT3 Transcription Factor / metabolism

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  • (PMID = 16709490.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / STAT3 Transcription Factor; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases
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67. Troxel DB: An insurer's perspective on error and loss in pathology. Arch Pathol Lab Med; 2005 Oct;129(10):1234-6
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  • Nearly one third of misdiagnoses involve melanoma misdiagnosed as Spitz nevus, "dysplastic" nevus, spindle cell squamous carcinoma, atypical fibroxanthoma, and dermatofibroma.

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  • (PMID = 16196510.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Miura Y, Misago N, Narisawa Y: Epithelioid cell histiocytoma with underlying artery damage. J Dermatol; 2005 Sep;32(9):721-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid cell histiocytoma with underlying artery damage.
  • Although epithelioid cell histiocytoma is considered a variant of fibrous histiocytoma (dermatofibroma), the histogenesis of this condition remains controversial.
  • A recent investigation suggested the possibility that epithelioid cell histiocytoma is an angioformative fibrous histiocytoma.
  • We report a case of epithelioid cell histiocytoma underlying a damaged artery.
  • This epithelioid cell histiocytoma with a central area of hemorrhage was associated with a medium-sized artery in the reticular dermis running vertically up to the lesion.
  • This case may support the view that epithelioid cell histiocytoma is a vascular and angioformative fibrous histiocytoma.
  • [MeSH-major] Epithelial Cells / pathology. Granuloma / pathology. Histiocytoma, Benign Fibrous / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16361715.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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69. Koga K, Nabeshima K, Nishimura N, Shishime M, Nakayama J, Iwasaki H: Microvessel density and HIF-1alpha expression correlate with malignant potential in fibrohistiocytic tumors. Eur J Dermatol; 2005 Nov-Dec;15(6):465-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, involvement of HIF-1alpha has never been studied in so-called fibrohistiocytic tumors, such as dermatofibroma (DF), dermatofibrosarcoma protuberans (DFSP) and malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Hypoxia-Inducible Factor 1, alpha Subunit / biosynthesis. Neoplasms, Fibrous Tissue / metabolism. Neoplasms, Fibrous Tissue / pathology. Skin Neoplasms / pathology

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  • (PMID = 16280300.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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70. Maier PC, Auw-Hädrich C, Reinhard T: [Recurrent fibrous histiocytoma at the corneoscleral limbus]. Klin Monbl Augenheilkd; 2008 Jan;225(1):99-100
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recurrent fibrous histiocytoma at the corneoscleral limbus].
  • [Transliterated title] Rezidivierendes fibröses Histiozytom am korneoskleralen Limbus.
  • This case report describes a rare fibrous histiocytoma at the corneoscleral limbus in a 10-year-old boy.
  • In our patient the tumour was histologically classified as benign, however, it presented with an invasive growth pattern and recurrency, so that a penetrating sclerokeratoplasty became necessary.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Keratoplasty, Penetrating. Limbus Corneae / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 18236380.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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71. Lee MH, Kim NR, Ryu JA: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol; 2010 Oct;39(10):981-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Of 23 masses, there were 5 giant cell tumors of the tendon sheath, 4 schwannomas, 3 vascular leiomyomas, 2 benign fibrous histiocytomas, 2 dermatofibrosarcoma protuberans, 2 granular cell tumors, 1 dermatofibroma, 1 fibroma of the tendon sheath, 1 fibromatosis, 1 eccrine spiradenoma, and 1 granulation tissue.
  • Such cases are not common, and fibrous tumors are the most frequent.

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  • [Cites] AJR Am J Roentgenol. 2008 Jun;190(6):1621-6 [18492916.001]
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  • (PMID = 20186412.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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72. Antal A, Zelger B, Reifenberger J, Niehues T, Feyen O, Megahed M, Ruzicka T, Homey B: Multiple eruptive myxoid dermatofibromas: report of first case and review of literature. Br J Dermatol; 2007 Aug;157(2):382-5
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  • Multiple eruptive dermatofibromas are a rare presentation of dermatofibroma which are frequently associated with underlying diseases such as human immunodeficiency virus infection or lupus erythematosus.
  • Comprehensive clinical and laboratory diagnostics showed no signs indicating any underlying disease.
  • We consider this case to be a unique presentation of multiple eruptive dermatofibroma showing massive deposition of mucin.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17596172.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Mucins
  • [Number-of-references] 38
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73. Tatsas AD, O'Leary MF, Wright JE, Robbins JB: Cutaneous focal mucinosis causing follicular induction of the epidermis. Am J Dermatopathol; 2009 Jul;31(5):462-4

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  • We present 2 cases of focal mucinosis with follicular induction and describe the histopathologic findings to create awareness of this association and to prevent confusion with other diagnoses such as dermatofibroma with follicular induction or superficial basal cell carcinoma.

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  • (PMID = 19542921.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Gencoglan G, Karaarslan IK, Akalin T, Ozdemir F: Trichilemmal cyst with homogeneous blue pigmentation on dermoscopy. Australas J Dermatol; 2009 Nov;50(4):301-2
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  • The lesion was excised with the pre-operative diagnosis of melanoma, blue naevus and dermatofibroma.
  • Although homogeneous blue pigmentation on dermoscopy is the hallmark of blue naevus, it may be seen in metastatic melanoma and exceptionally in hemosiderotic and cellular types of dermatofibroma.

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  • (PMID = 19916979.001).
  • [ISSN] 1440-0960
  • [Journal-full-title] The Australasian journal of dermatology
  • [ISO-abbreviation] Australas. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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75. Troxel DB: Medicolegal aspects of error in pathology. Arch Pathol Lab Med; 2006 May;130(5):617-9
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  • Nearly one third involved melanoma misdiagnosed as Spitz nevus, "dysplastic" nevus, spindle cell squamous carcinoma, atypical fibroxanthoma, and dermatofibroma.

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  • (PMID = 16683874.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Huang PY, Chu CY, Hsiao CH: Multiple eruptive dermatofibromas in a patient with dermatomyositis taking prednisolone and methotrexate. J Am Acad Dermatol; 2007 Nov;57(5 Suppl):S81-4
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  • Dermatofibroma (DF) is a common, benign, dermal tumor, often occurring as a single lesion.
  • [MeSH-major] Dermatomyositis / drug therapy. Glucocorticoids / adverse effects. Histiocytoma, Benign Fibrous / chemically induced. Immunosuppressive Agents / adverse effects. Methotrexate / adverse effects. Prednisolone / adverse effects. Skin Neoplasms / chemically induced

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  • (PMID = 17097372.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucocorticoids; 0 / Immunosuppressive Agents; 9PHQ9Y1OLM / Prednisolone; YL5FZ2Y5U1 / Methotrexate
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77. Lisovsky M, Hoang MP, Dresser KA, Kapur P, Bhawan J, Mahalingam M: Apolipoprotein D in CD34-positive and CD34-negative cutaneous neoplasms: a useful marker in differentiating superficial acral fibromyxoma from dermatofibrosarcoma protuberans. Mod Pathol; 2008 Jan;21(1):31-8
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  • Of the remaining CD34-positive lesions, Apo D expression was noted in 35/36 (97%) cases of dermatofibrosarcoma protuberans, 3/5 (60%) giant-cell fibroblastomas, 4/4 (100%) sclerotic fibromas, 8/8 (100%) neurofibromas, and 1/1 (100%) solitary fibrous tumor.
  • Of the CD34-negative lesions, Apo D expression was noted in 2/22 (9%) regular dermatofibroma, 23/45 (51%) cellular dermatofibroma, 10/10 (100%) malignant fibrous histiocytoma, 9/10 (90%) atypical fibroxanthoma, 7/8 (86%) cellular neurothekeoma, 9/9 (100%) malignant melanoma, 8/8 (100%) melanocytic nevi (100%), 0/2 superficial angiomyxoma, 0/15 fibromatosis, 0/1 nodular fasciitis, and 1/2 (50%) desmoplastic fibroblastomas.
  • Although strong positive staining of Apo D in a markedly atypical fibrohistiocytic lesion is suggestive of atypical fibroxanthoma and/or malignant fibrous histiocytoma, further studies with the inclusion of other atypical spindled cell neoplasms are required to conclusively prove the same.
  • [MeSH-minor] Diagnosis, Differential. Giant Cell Tumors / chemistry. Giant Cell Tumors / diagnosis. Giant Cell Tumors / immunology. Histiocytoma, Benign Fibrous / chemistry. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / immunology. Humans. Immunohistochemistry. Melanoma / chemistry. Melanoma / diagnosis. Melanoma / immunology. Nevus, Pigmented / chemistry. Nevus, Pigmented / diagnosis. Nevus, Pigmented / immunology. Reproducibility of Results. United States

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  • (PMID = 17885669.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Apolipoproteins D; 0 / Biomarkers, Tumor
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78. Orrock JM, Abbott JJ, Gibson LE, Folpe AL: INI1 and GLUT-1 expression in epithelioid sarcoma and its cutaneous neoplastic and nonneoplastic mimics. Am J Dermatopathol; 2009 Apr;31(2):152-6
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  • The morphological features of epithelioid sarcoma may closely mimic those of epithelial neoplasms, such as squamous cell carcinoma, mesenchymal tumors, such as benign fibrous histiocytoma, and nonneoplastic lesions, such as granuloma annulare.
  • Twenty-four cases of epithelioid sarcoma, 13 cases of granuloma annulare, 10 cases of rheumatoid nodule, 19 cases of cutaneous squamous cell carcinoma, 7 cases of atypical fibroxanthoma, 9 cases of benign fibrous histiocytoma (dermatofibroma), and 3 cases of nodular fasciitis were immunostained for GLUT-1 and INI1 using commercially available antibodies, heat-induced epitope retrieval, and the Dako Envision detection system.
  • GLUT-1 was positive in 40%-50% of epithelioid sarcomas, all cases of granuloma annulare and rheumatoid nodules, 67% of benign fibrous histiocytomas, and in all squamous cell carcinomas.
  • In contrast, atypical fibroxanthomas and cases of nodular fasciitis were consistently GLUT-1 negative.
  • In this clinical context, loss of INI1 expression seems to be an entirely specific marker of epithelioid sarcoma and this finding may be of great value in distinguishing CD34-negative epithelioid sarcoma from squamous cell carcinoma and in the distinction of rare cytokeratin-negative epithelioid sarcomas from necrobiotic processes, nodular fasciitis, and benign fibrous histiocytomas.
  • [MeSH-minor] Biomarkers / metabolism. Diagnosis, Differential. Fasciitis / metabolism. Fasciitis / pathology. Histiocytoma, Benign Fibrous / metabolism. Histiocytoma, Benign Fibrous / pathology. Humans. Neoplasms, Squamous Cell / metabolism. Neoplasms, Squamous Cell / pathology. Rheumatoid Nodule / metabolism. Rheumatoid Nodule / pathology. Xanthomatosis / metabolism. Xanthomatosis / pathology

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  • (PMID = 19318800.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / Glucose Transporter Type 1; 0 / SMARCB1 protein, human; 0 / Transcription Factors
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79. Scope A, Benvenuto-Andrade C, Agero AL, Marghoob AA: Nonmelanocytic lesions defying the two-step dermoscopy algorithm. Dermatol Surg; 2006 Nov;32(11):1398-406
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Seborrheic keratosis, solar lentigo, dermatofibroma, and supernumerary accessory nipple may present with network-like structures.
  • Seborrheic keratosis, dermatofibroma, subcorneal hemorrhage, basal cell carcinoma (BCC), and cutaneous metastases of breast and other cancers may contain pigmented globules.
  • Homogenous bluish pigmentation, simulating a blue nevus, can also be seen in benign vascular lesions, Kaposi sarcoma, radiation tattoo, and BCC.

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  • (PMID = 17083595.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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80. Plaza JA, Torres-Cabala C, Evans H, Diwan HA, Suster S, Prieto VG: Cutaneous metastases of malignant melanoma: a clinicopathologic study of 192 cases with emphasis on the morphologic spectrum. Am J Dermatopathol; 2010 Apr;32(2):129-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous metastases of malignant melanoma: a clinicopathologic study of 192 cases with emphasis on the morphologic spectrum.
  • In up to 5% of patients, metastatic melanoma can be the first manifestation of the disease.
  • For the most part, the histologic diagnosis of metastatic melanoma poses little diagnostic difficulty; however, some metastases may adopt unusual or unfamiliar appearances mimicking other benign and malignant conditions.
  • We present a study of 192 cases of cutaneous metastatic melanomas with special emphasis on their spectrum of morphologic features.
  • One hundred ten cases showed the classic morphologic appearance of melanoma (well-circumscribed epithelioid dermal/subcutaneous nodule), 82 cases showed unusual histologic appearances that mimicked other benign and malignant neoplasms.
  • In 16 patients (8.3%), there was no evidence of primary melanoma and the cutaneous metastasis was the only manifestation of the disease.
  • Unusual features observed in this series included examples of cutaneous metastatic melanoma that closely simulated metastatic carcinoma, dermatofibroma, leiomyosarcoma, angiosarcoma, nevoid melanoma, halo nevus, blue nevi, and atypical fibroxanthoma.

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  • (PMID = 20010406.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Antigens, Neoplasm; 0 / CD68 antigen, human; 0 / Desmin; 0 / Ki-67 Antigen; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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81. Kaçar N, Tasli L, Argenziano G, Demirkan N: Reticulohistiocytosis: different dermatoscopic faces and a good response to methotrexate treatment. Clin Exp Dermatol; 2010 Jun;35(4):e120-2
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  • In four lesions, brown reticular structures surrounded a central white scar-like patch resembling that of a dermatofibroma.
  • However, the presence of the setting-sun pattern in the background gave a different hue to that of the peripheral network seen in a dermatofibroma.

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  • (PMID = 19886958.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dermatologic Agents; YL5FZ2Y5U1 / Methotrexate
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82. Wang WL, Patel KU, Coleman NM, Smith-Zagone MJ, Ivan D, Reed JA, López-Terrada D, Lazar AJ, Prieto VG: COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin. Am J Dermatopathol; 2010 Apr;32(2):149-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Indeterminate fibrohistiocytic lesions of the skin share histological and immunohistochemical features of both benign fibrous histiocytoma/dermatofibroma and dermatofibrosarcoma protuberans (DFSP).
  • Unlike dermatofibroma, DFSP harbors recurrent genetic aberrations resulting in the fusion of COL1A1 on chromosome 17 and PDGFB on chromosome 22.
  • [MeSH-major] Chimera / genetics. Collagen Type I / genetics. Dermatofibrosarcoma / genetics. Histiocytoma, Benign Fibrous / genetics. Proto-Oncogene Proteins c-sis / genetics. Skin Neoplasms / genetics

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  • (PMID = 19940748.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Collagen Type I; 0 / Proto-Oncogene Proteins c-sis; 0 / collagen type I, alpha 1 chain
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83. Cangelosi JJ, Prieto VG, Baker GF, Moore BA, Diwan AH: Unusual presentation of multiple epithelioid cell histiocytomas. Am J Dermatopathol; 2008 Aug;30(4):373-6
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  • [Title] Unusual presentation of multiple epithelioid cell histiocytomas.
  • Epithelioid cell histiocytoma (ECH) is a variant of dermatofibroma that presents typically as a solitary nodule.
  • [MeSH-major] Arm / pathology. Histiocytoma, Benign Fibrous / pathology. Neoplasms, Multiple Primary / pathology. Nose Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 18645309.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Espiñeira-Carmona MJ, Arias-Santiago S, Aneiros-Fernández J, Fernández-Pugnaire MA, Naranjo-Sintes R: Exophytic and ulcerated lesion on the leg. Dermatol Online J; 2010;16(10):12
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  • After surgical excision the histological study confirmed the diagnosis of a polypoid dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Skin Ulcer / pathology

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  • (PMID = 21062606.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Leonard N, Panting K, Kelly SA, Ellison JE: An unclassifiable cellular myofibroblastic proliferation with an unusual clinical presentation. Clin Exp Dermatol; 2009 Dec;34(8):e843-6
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  • Multiple biopsies had been taken, all showing similar histopathological features of a poorly differentiated dermal lesion composed of fibrohistiocytic cells arranged in a whorled pattern, similar to that seen in dermatofibroma.
  • Clinically this extensive lesion does not fit the characteristics of a dermatofibroma.
  • It also does not fit readily into any previously described fibrous tissue tumour condition, and, to our knowledge, is a unique case.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Leg / pathology. Skin Neoplasms / pathology

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  • (PMID = 19817759.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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86. Swan MC, Banwell PE, Hollowood K, Goodacre TE: Late recurrence of dermatofibrosarcoma protuberans in the female breast: a case report. Br J Plast Surg; 2005 Jan;58(1):84-7
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  • The case presented is of a 39-year-old female who, at the age of 13 years, had had a "dermatofibroma" excised from her left breast.

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  • (PMID = 15629172.001).
  • [ISSN] 0007-1226
  • [Journal-full-title] British journal of plastic surgery
  • [ISO-abbreviation] Br J Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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87. Sinovich V, Hollowood K, Burge S: Atrophic dermatofibrosarcoma protuberans. Australas J Dermatol; 2005 May;46(2):114-7
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  • Five years earlier a punch biopsy of the same lesion had been carried out and a diagnosis of dermatofibroma was made.

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  • (PMID = 15842408.001).
  • [ISSN] 0004-8380
  • [Journal-full-title] The Australasian journal of dermatology
  • [ISO-abbreviation] Australas. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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88. de Giorgi V, Sestini S, Massi D, Papi F, Lotti T: Atypical Spitz tumour: a 'chameleon' lesion. Clin Exp Dermatol; 2008 May;33(3):309-11
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  • The term 'Spitz tumour' has been proposed for these lesions, as the term 'naevus' indicates a lesion that is completely benign and presents no risk to the patient.
  • In fact, the lesion appeared as a benign and nonmelanocytic lesion, a pigmented dermatofibroma.

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  • (PMID = 18201260.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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89. Zalaudek I, Ferrara G, Di Stefani A, Argenziano G: Dermoscopy for challenging melanoma; how to raise the 'red flag' when melanoma clinically looks benign. Br J Dermatol; 2005 Jul;153(1):200-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopy for challenging melanoma; how to raise the 'red flag' when melanoma clinically looks benign.
  • Melanoma may mimic clinically a number of benign skin tumours by exhibiting overlapping features that do not allow accurate differentiation.
  • The case presented here refers to a melanoma clinically simulating dermatofibroma that was biopsied because dermoscopic examination revealed unusual features that did not confirm the clinical diagnosis.
  • [MeSH-minor] Adult. Dermoscopy. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Leg

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  • (PMID = 16029351.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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90. Pérez LP, Zulaica A, Rodríguez L, Campo MC, Peñaranda JM, Fernández-Redondo V, Toribio J: Multinucleate cell angiohistiocytoma. Report of five cases. J Cutan Pathol; 2006 May;33(5):349-52
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  • It must be distinguished from other diverse cutaneous lesions, notably dermatofibroma, Kaposi sarcoma, and angiofibroma.
  • [MeSH-major] Histiocytoma / pathology. Skin / blood supply. Skin Diseases / pathology

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  • (PMID = 16640541.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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91. Rubenstein MA, Farnsworth NN, Pielop JA, Orengo IF, Curry JL, Drucker CR, Hsu S: Cutaneous Rosai-Dorfman disease. Dermatol Online J; 2006;12(1):8
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  • [Title] Cutaneous Rosai-Dorfman disease.
  • Sinus histiocytosis with massive lymphadenopathy, or Rosai-Dorfman disease, is a benign idiopathic histiocytic proliferative disorder that commonly involves the lymph nodes but secondarily may involve the skin.
  • However, purely cutaneous disease without lymphadenopathy or internal organ involvement rarely may occur.
  • We present case reports of three patients who presented with asymptomatic nonspecific enlarging skin nodules without evidence of lymphadenopathy or internal disease.
  • Histopathologic examination of skin lesions in all patients showed proliferation of large histiocytes with phagocytosed inflammatory cells characteristic of Rosai-Dorfman disease.
  • However, the diagnoses of dermatofibroma, other spindle cell neoplasm, infectious granulomatous process, and other xanthohistiocytic proliferations were also considered due to the presence of storiform spindle cells and foamy cells in the first case.
  • In the absence of massive lymphadenopathy characteristic of Rosai-Dorfman disease, the diagnosis of purely cutaneous Rosai-Dorfman disease may be complicated by the rarity, non-specific clinical appearance of skin lesions, and broad histopathological differential diagnosis of this disorder.

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  • (PMID = 16638376.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Yeh I, Tran DT, Davis TL, Argenyi ZB: An infiltrative variant of non-neural granular cell tumor: a case report. J Cutan Pathol; 2009 Oct;36 Suppl 1:46-51
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  • Our case could represent a dermal non-neural granular cell tumor with unique architecture, a granular cellular neurothekeoma or a granular cell dermatofibroma.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / metabolism. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Immunohistochemistry. Middle Aged. Scapula / pathology. Scapula / surgery

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  • (PMID = 19187104.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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93. Cham E, Siegel D, Ruben BS: Cutaneous xanthogranulomas, hepatosplenomegaly, anemia, and thrombocytopenia as presenting signs of juvenile myelomonocytic leukemia. Am J Clin Dermatol; 2010;11(1):67-71
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  • Although cutaneous juvenile xanthogranulomas are benign lesions, in several reported cases they have been shown to herald leukemia.
  • Juvenile xanthogranulomas have a number of morphologic variants and clinical presentations that can be confused with the cutaneous lesions of Langerhans cell histiocytosis and dermatofibroma.

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  • (PMID = 20000879.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
  • [Chemical-registry-number] 0 / Antimetabolites; E7WED276I5 / 6-Mercaptopurine
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94. Su W, Kheir SM, Berberian B, Cockerell CJ: Merkel cell carcinoma in situ arising in a trichilemmal cyst: a case report and literature review. Am J Dermatopathol; 2008 Oct;30(5):458-61
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  • A 73-year-old man presented with a 4-mm asymptomatic, smooth, dome-shaped lesion on the right fourth finger with a clinical impression of a cyst/dermatofibroma.
  • Dermal Merkel cell carcinoma (MCC) arising in association with benign adnexal tumors or cysts, with or without epithelial involvement, is a rare event.

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  • (PMID = 18806489.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-20
  • [Number-of-references] 46
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95. Zaballos P, Llambrich A, Puig S, Malvehy J: Dermoscopy is useful for the recognition of benign-malignant compound tumours. Br J Dermatol; 2005 Sep;153(3):653-6
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  • [Title] Dermoscopy is useful for the recognition of benign-malignant compound tumours.
  • In cases where a malignant neoplasm exists in association with a benign lesion it is important to make an accurate diagnosis in order to treat the lesions correctly.
  • We describe the dermoscopic characteristics of various collision or compound tumours that were composed of benign and malignant neoplasms: two cases of seborrhoeic keratosis associated with basal cell carcinoma, two cases of melanocytic naevus and basal cell carcinoma and one case of dermatofibroma associated with basal cell carcinoma.
  • [MeSH-minor] Adult. Aged. Carcinoma, Basal Cell / diagnosis. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Keratosis, Seborrheic / diagnosis. Male. Middle Aged. Nevus, Pigmented / diagnosis

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  • (PMID = 16120160.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 14
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96. Bhadani PP, Sen R, Bhadani UK, Karki S, Agarwal S: Is fine needle aspiration cytology (FNAC) useful in skin adnexal masses? A study on 5 cases of pilomatixoma. Indian J Pathol Microbiol; 2007 Apr;50(2):411-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Superficial cutaneous/subcutaneous nodules, caused by a variety of inflammatory, benign and malignant pathology of diverse origin, are tempting lesion for fine needle aspiration cytology (FNAC).
  • Pre FNAC clinical diagnoses were sebaceous cyst, tuberculous lymphadenopathy, dermatofibroma, reactive lymphadenopathy and lipoma.
  • PMX was diagnosed on FNAC in 3 cases on finding groups of basaloid cells, ghost epithelial cells, pink fibrillary material and calcium deposits.

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  • (PMID = 17883095.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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97. Rahman MT, Monami NS, Ferdousi S, Tahmin T: Skin biopsy and psoriasis. Mymensingh Med J; 2010 Jul;19(3):353-9
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  • Ashy dermatosis 3(9.09%), Nevus 2(6.06%) and corn, hemangioma, prurigo simplex, pityriasis rubra pilaris (PRP), dermatofibroma, 1(3.03%) each.

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  • (PMID = 20639826.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Bangladesh
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98. Kilinc Karaarslan I, Gencoglan G, Akalin T, Ozdemir F: Different dermoscopic faces of dermatofibromas. J Am Acad Dermatol; 2007 Sep;57(3):401-6
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  • In addition, dermoscopic features of an atrophic variant of dermatofibroma are described, which was seen in one lesion (1.9%).
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17560684.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Dhouib RS, Sassi S, Jbeli A, Driss M, Mrad K, Abbes I, Ben Romdhane K: Desmoplastic spitz nevus: report of a case and review of the literature. Pathologica; 2008 Jun;100(3):181-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The histologic features of this benign tumour may mimic those of certain benign (dermatofibroma and desmoplastic cellular blue nevus) or malignant (metastatic carcinoma and malignant melanoma) neoplasms.
  • The histologic presentation of this benign lesion mimics both benign and malignant neoplasms.

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  • (PMID = 18841824.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 15
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100. Zaballos P, Puig S, Llambrich A, Malvehy J: Dermoscopy of dermatofibromas: a prospective morphological study of 412 cases. Arch Dermatol; 2008 Jan;144(1):75-83
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  • CONCLUSION: The most common pattern associated with dermatofibroma is the classic dermoscopic pattern (pigment network and central white patch), but this tumor has a wide range of presentations.
  • [MeSH-major] Dermoscopy / methods. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18209171.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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