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Items 1 to 63 of about 63
1. Rosa N, Lanza M, Cennamo G, Accardo M: Pilomatrixoma of the eyelid. J Dermatol Case Rep; 2008 Jul 7;2(2):21-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilomatrixoma of the eyelid.
  • BACKGROUND: Pilomatrixoma is a benign tumor of the hair follicle that can transform into a malignant lesion, the pilomatrix carcinoma.
  • We present an unusual case of an eyelid pilomatrixoma.
  • MAIN OBSERVATION: A 37-year-old white male presented with rapidly growing, pedunculated lesion located at the superior right eyelid of five months duration.
  • Results of both examinations were consistent with a benign pilomatrixoma.
  • CONCLUSIONS: Even though the lesion had malignant clinical appearance, histopathology confirmed the diagnosis of a benign pilomatrixoma, supporting the decision not to make a more extensive surgery.

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  • [Cites] Arch Dermatol. 1961 Apr;83:606-18 [13700704.001]
  • [Cites] J Pediatr Surg. 2006 Oct;41(10):1755-8 [17011283.001]
  • [Cites] Arch Derm Syphilol. 1949 May;59(5):506-18 [18127498.001]
  • [Cites] Arch Ophthalmol. 1983 Aug;101(8):1209-10 [6882248.001]
  • [Cites] Indian J Ophthalmol. 2008 Jan-Feb;56(1):83-4 [18158418.001]
  • [Cites] Ophthal Plast Reconstr Surg. 2008 Jan-Feb;24(1):60-2 [18209650.001]
  • [Cites] Cancer. 1993 Apr 15;71(8):2491-8 [8453573.001]
  • (PMID = 21886706.001).
  • [ISSN] 1898-7249
  • [Journal-full-title] Journal of dermatological case reports
  • [ISO-abbreviation] J Dermatol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC3157770
  • [Keywords] NOTNLM ; eyelid / pilomatrixoma / skin neoplasm
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2. Rodallec T, Abada S, Nordmann JP: [Atypical giant hidrocystoma of the eyelid]. J Fr Ophtalmol; 2006 Feb;29(2):226-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Atypical giant hidrocystoma of the eyelid].
  • Hidrocystoma belongs to benign tumors of sweat glands.
  • We report an atypical case of giant hidrocystoma of the eyelid.
  • A 27-year-old woman consulted for a gradually progressing tumor of the right upper eyelid, with ptosis.
  • The tumor was excised, and the histopathological exam revealed a giant hidrocystoma.
  • [MeSH-major] Eyelid Neoplasms / pathology. Hidrocystoma / pathology

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  • (PMID = 16523166.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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3. Wali UK, Al-Mujaini A: Sebaceous gland carcinoma of the eyelid. Oman J Ophthalmol; 2010 Sep;3(3):117-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous gland carcinoma of the eyelid.
  • It represents 1-5.5% of eyelid malignancies and is considered to be the third most common eyelid malignancy after basal cell and squamous cell carcinomas, although few reports placed this tumor as second most common after basal cell carcinoma.
  • A delay in diagnosis, which can be attributed primarily to ability of this tumor to masquerade as more benign conditions, often leads to inappropriate management with increased morbidity and mortality rates.

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  • (PMID = 21120046.001).
  • [ISSN] 0974-7842
  • [Journal-full-title] Oman journal of ophthalmology
  • [ISO-abbreviation] Oman J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2992157
  • [Keywords] NOTNLM ; Moh’s / nodular / pagetoid / sebaceous gland carcinoma
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4. Bernardini FP: Management of malignant and benign eyelid lesions. Curr Opin Ophthalmol; 2006 Oct;17(5):480-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of malignant and benign eyelid lesions.
  • PURPOSE OF REVIEW: The management of benign and malignant eyelid neoplasms has been extensively examined.
  • This paper offers an overview of the most common eyelid lesions and their management based on a review of the relevant bibliography.
  • RECENT FINDINGS: Recent studies have focused on the results of nonsurgical approaches for benign and premalignant lesions that are routinely surgically excised.
  • In the malignant group, a consensus has been reached over the preferred method of tumor excision for basal cell carcinoma: Mohs surgery or complete surgical excision with frozen-section control of the margins offers the lowest tumor-recurrence rate.
  • Intraepithelial tumor growth is a peculiar feature of sebaceous gland carcinoma that seems to indicate an increased risk for orbital invasion.
  • Recent reports regarding the rare tumor, Merkel cell carcinoma, recommend a wide surgical excision with 5 mm margins; this may reduce the incidence of lymph-node metastasis, haematogenous spread and local recurrences.
  • SUMMARY: Although treatment of the most common benign and malignant tumours affecting the eyelids has not radically changed over the years, recent reports have significantly improved the standard of care for affected patients.
  • [MeSH-major] Eyelid Neoplasms / surgery. Ophthalmologic Surgical Procedures

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  • (PMID = 16932064.001).
  • [ISSN] 1040-8738
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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5. Al Baghli A, Reddy SS, Reddy MA: Malignant nodular hidradenoma of the eyelid: a rare sweat gland tumor. Middle East Afr J Ophthalmol; 2010 Oct;17(4):374-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant nodular hidradenoma of the eyelid: a rare sweat gland tumor.
  • We report a case of malignant nodular hidradenoma in a middle-aged man, who presented with a nodular swelling in the eyelid.
  • The tumor was similar to its benign counterpart but had additional features such as surface ulceration, numerous mitiotic figures, and an infiltrative growth pattern.
  • Malignant forms of hidradenomas are unusual and the possibility this variant should be considered in the differential diagnosis of eyelid tumors.

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  • (PMID = 21180442.001).
  • [ISSN] 0975-1599
  • [Journal-full-title] Middle East African journal of ophthalmology
  • [ISO-abbreviation] Middle East Afr J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2991459
  • [Keywords] NOTNLM ; Eccrine Glands / Nodular Hidradenoma / Sweat Gland Tumor
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6. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T: [Incidence of benign and malignant lesions of eyelid and conjunctival tumors]. Nippon Ganka Gakkai Zasshi; 2005 Sep;109(9):573-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Incidence of benign and malignant lesions of eyelid and conjunctival tumors].
  • PURPOSE: To examine the incidence of benign and malignant eyelid lesions and conjunctival tumors.
  • SUBJECTS AND METHODS: One-hundred-and twenty-eight cases (131 eyes) which were treated during the period from January 1990 to February 2004 were histopathologically diagnosed for eyelid or conjunctival tumors (87 cases of eyelid tumors and 41 cases of conjunctival tumors) in retrospective evaluations.
  • The incidence of benign or malignant lesions, the pathological classification, age, sex, and clinical diagnostic accuracy were all investigated.
  • RESULTS: Sixty-four (73%) of the tumors were found to be benign eyelid tumors.
  • The common benign eyelid tumors were 14 nevocellular nevi, 9 seborrheic keratosis, 7 epidermoid cysts, and 6 papillomas.
  • Twenty-four (27%) eyelid tumors were malignant.
  • Thirty-four (79%) conjunctival tumors were benign, and the common benign conjunctival tumors were 9 nevocellular nevi and 7 papillomas.
  • The mean ages of malignant eyelid and conjunctival tumor patients were significantly older than those of benign tumor patients.
  • CONCLUSIONS: Approximately 70 approximately 80% of all eyelid and conjunctival tumors are benign.
  • Clinicians should suspect that the lesions are malignant when seeing elderly patients with eyelid or conjunctival tumors.
  • Excised eyelid lesions should be submitted for histopathologic confirmation because there are some cases where clinical diagnosis does not match pathological diagnosis.
  • [MeSH-major] Conjunctival Neoplasms / epidemiology. Eyelid Neoplasms / epidemiology

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  • (PMID = 16218435.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 27
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7. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A: Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol; 2009 Jul-Aug;57(4):318-20
Genetic Alliance. consumer health - Schwannoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Schwannoma of the eyelid: apropos of two cases.
  • Schwannoma, also referred to as neurilemmoma, is a benign tumor of peripheral nerve arising from Schwann cells that form the neural sheath.
  • Isolated eyelid schwannoma is extremely uncommon.
  • Herein, we report two cases of eyelid schwannoma.
  • [MeSH-major] Eyelid Neoplasms / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Antigens, Neoplasm / metabolism. Female. Humans. Immunochemistry. Male. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism. Rare Diseases. S100 Proteins / metabolism. Young Adult

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  • [Cites] Br J Ophthalmol. 1982 Mar;66(3):194-204 [7066273.001]
  • [Cites] Arch Ophthalmol. 1984 Nov;102(11):1650 [6497748.001]
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  • [Cites] Arch Ophthalmol. 1996 Oct;114(10):1258-60 [8859089.001]
  • (PMID = 19574706.001).
  • [ISSN] 1998-3689
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  • [Other-IDs] NLM/ PMC2712707
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8. Chi MJ, Baek SH: Clinical analysis of benign eyelid and conjunctival tumors. Ophthalmologica; 2006;220(1):43-51
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical analysis of benign eyelid and conjunctival tumors.
  • PURPOSE: To assess the relative frequency and clinicopathologic characteristics of benign conjunctival tumors.
  • METHODS: A retrospective study of 80 consecutive patients admitted to our hospital with benign eyelid and conjunctival tumor between April 2000 and November 2002 was undertaken, and clinical records including age, sex and involved site of tumors and pathology slides of the patients were reviewed retrospectively.
  • RESULTS: Twenty-three males and 33 females presented with benign eyelid tumors and 12 males and 12 females with conjunctival tumors.
  • The lower eyelid was involved in 27 (48.2%) of eyelid tumors and the medial conjunctiva in 14 (58.3%) of conjunctival tumors.
  • The most frequent tumor was intradermal nevus (44.6%), seborrheic keratosis (16.1%) and compound nevus (10.7%) in eyelid tumors, and compound nevus (29.2%) and intradermal nevus (25.0%) in conjunctival tumors.
  • CONCLUSION: This report will provides a basic analysis of benign eyelid and conjunctival tumors.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Eyelid Neoplasms / pathology. Keratosis, Seborrheic / pathology. Nevus, Intradermal / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy. Conjunctiva / pathology. Diagnosis, Differential. Eyelids / pathology. Female. Humans. Male. Middle Aged. Prevalence. Retrospective Studies

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  • [Copyright] 2006 S. Karger AG, Basel
  • (PMID = 16374048.001).
  • [ISSN] 0030-3755
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Switzerland
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9. Barbarino S, McCormick SA, Lauer SA, Milman T: Syringocystadenoma papilliferum of the eyelid. Ophthal Plast Reconstr Surg; 2009 May-Jun;25(3):185-8
Genetic Alliance. consumer health - Syringocystadenoma papilliferum.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Syringocystadenoma papilliferum of the eyelid.
  • PURPOSE: To describe 6 patients with syringocystadenoma papilliferum of the eyelid and to review the literature regarding this rare eyelid tumor.
  • The PubMed database was searched for reported cases of syringocystadenoma papilliferum of the eyelid (keywords: syringocystadenoma, eyelid, apocrine, eccrine).
  • RESULTS: Fourteen patients (6 from the current case series and 8 previously reported) with syringocystadenoma papilliferum of the eyelid were identified.
  • Most cases had a preoperative diagnosis of basal cell carcinoma or cyst.
  • None of the lesions was associated with a malignant neoplasm.
  • CONCLUSIONS: Syringocystadenoma papilliferum can rarely affect eyelid skin.
  • Although syringocystadenoma papilliferum of the eyelid can be associated with other benign lesions, no malignant transformation or association with malignant neoplasms has been reported.
  • The evidence suggests that this tumor should be managed with conservative complete excision.
  • [MeSH-major] Cystadenoma / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19454927.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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10. Procianoy F, Golbert MB, Golbspan L, Duro KM, Bocaccio FJ: Steatocystoma simplex of the eyelid. Ophthal Plast Reconstr Surg; 2009 Mar-Apr;25(2):147-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Steatocystoma simplex of the eyelid.
  • A 68-year-old woman presented with a nodular pretarsal tumor on her right upper eyelid that had slowly grown over 6 months.
  • Excisional biopsy was performed through an eyelid crease approach, and histopathology evidenced the lesion to be steatocystoma simplex.
  • Steatocystoma simplex is an uncommon benign cutaneous lesion thought to be a circumscribed malformation arising from the pilosebaceous duct junction, rarely reported to occur in the periorbital region.
  • [MeSH-major] Epidermal Cyst / pathology. Eyelid Diseases / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans

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  • (PMID = 19300166.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Pyatetsky D, Lissner GS, Bryar PJ, Lasky JB: Fibrous histiocytoma of the eyelid obliterating the punctum and the canaliculus. J Pediatr Ophthalmol Strabismus; 2007 Nov-Dec;44(6):379-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous histiocytoma of the eyelid obliterating the punctum and the canaliculus.
  • A 17-year-old boy with a growth in the medial right lower eyelid obliterating the lower punctum and canaliculus underwent incisional biopsy, which revealed fibrous histiocytoma.
  • The remaining tumor was excised and the eyelid was reconstructed.
  • [MeSH-major] Eyelid Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adolescent. Biopsy. Diagnosis, Differential. Eyelids / pathology. Eyelids / surgery. Follow-Up Studies. Humans. Male. Ophthalmologic Surgical Procedures / methods. Reconstructive Surgical Procedures / methods

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  • (PMID = 18062498.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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12. Pornpanich K, Chindasub P: Eyelid tumors in Siriraj Hospital from 2000-2004. J Med Assoc Thai; 2005 Nov;88 Suppl 9:S11-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eyelid tumors in Siriraj Hospital from 2000-2004.
  • OBJECTIVES: To determine the relative incidence of eyelid lesions seen in Siriraj Hospital from January 2000-April 2004.
  • STUDY DESIGN: Retrospective charts review MATERIAL AND METHOD: Two hundred and ninety-seven cases of eyelid lesions seen in Siriraj Hospital from 2000 to 2004 were analyzed.
  • RESULTS: There were 53 (17.8%) inflammatory conditions, 212 (71.4%) benign eyelid tumors and 32 (10.8%) malignant eyelid tumors.
  • These 32 malignant eyelid tumors included 13 sebaceous gland carcinomas, 12 basal cell carcinomas, 3 malignant melanomas, 2 squamous cell carcinomas, 1 apocrine adenocarcinoma and 1 metastatic carcinoma.
  • CONCLUSION: The majority of eyelid lesions were benign eyelid tumors while malignant eyelid tumors contributed 10.8% of the total eyelid lesions.
  • Sebaceous gland carcinoma was the most common eyelid tumor found in their present study that was consistent with other studies from Asian countries.
  • [MeSH-major] Carcinoma, Basal Cell / epidemiology. Carcinoma, Squamous Cell / epidemiology. Eyelid Neoplasms / epidemiology. Sebaceous Gland Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Biopsy, Needle. Child. Child, Preschool. Female. Humans. Immunohistochemistry. Incidence. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Risk Assessment. Sex Distribution. Thailand / epidemiology

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  • (PMID = 16681045.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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13. Peralejo B, Beltrani V, Bielory L: Dermatologic and allergic conditions of the eyelid. Immunol Allergy Clin North Am; 2008 Feb;28(1):137-68, vii
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatologic and allergic conditions of the eyelid.
  • This article reviews the dermatologic and allergic conditions of the eyelid.
  • Topics include various eyelid dermatitis, inflammatory lesions, infections, benign and malignant tumor, urticaria, vascular lesions, and others.
  • Treatment considerations for these conditions of the eyelid are also discussed.
  • [MeSH-major] Blepharitis / immunology. Eyelids / immunology. Hypersensitivity. Skin Diseases / immunology

  • MedlinePlus Health Information. consumer health - Allergy.
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  • (PMID = 18282550.001).
  • [ISSN] 0889-8561
  • [Journal-full-title] Immunology and allergy clinics of North America
  • [ISO-abbreviation] Immunol Allergy Clin North Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 152
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14. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR: Schwannoma of the eyelid: report of two cases. Dermatol Online J; 2007;13(2):12
Genetic Alliance. consumer health - Schwannoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Schwannoma of the eyelid: report of two cases.
  • Schwannomas are rare benign neurogenic tumors that show differentiation of Schwann cells that form the neural sheath.
  • Only five reports of eyelid schwannomas in adults have been found in the English literature.
  • We report the unusual cases of two females, aged 41 and 70 years, who developed eyelid schwannomas.
  • Neither tumor was diagnosed clinically; both were erroneously considered as epidermal inclusion cysts.
  • The diagnosis of schwannoma was made.
  • This entity should be included in the differential diagnosis of eyelid tumors.
  • [MeSH-major] Epidermal Cyst / pathology. Eyelid Neoplasms / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Rare Diseases. Treatment Outcome

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  • (PMID = 17498431.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Sugano DM, Lucci LM, Avila MP, Rehder JR, Pettinati J: [Eyelid trichoepithelioma--report of 2 cases]. Arq Bras Oftalmol; 2005 Jan-Feb;68(1):136-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Eyelid trichoepithelioma--report of 2 cases].
  • [Transliterated title] Tricoepitelioma palpebral--relato de 2 casos.
  • Trichoepithelioma is a benign skin tumor and is most commonly found on the face, however, there are few reports about its occurrence on the eyelids.
  • The purpose of this paper is to report two cases of solitary trichoepithelioma on the eyelid, their histopathology and treatment.
  • [MeSH-major] Eyelid Neoplasms / pathology. Neoplasms, Basal Cell / pathology. Skin Neoplasms / pathology

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  • (PMID = 15824820.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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16. Looi A, Kazim M, Cortes M, Rootman J: Orbital reconstruction after eyelid- and conjunctiva-sparing orbital exenteration. Ophthal Plast Reconstr Surg; 2006 Jan-Feb;22(1):1-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital reconstruction after eyelid- and conjunctiva-sparing orbital exenteration.
  • PURPOSE: To describe the technique and results of eyelid- and conjunctiva-sparing orbital exenteration with temporalis transfer and dermis-fat graft.
  • The last patient had eyelid-sparing exenteration performed more than 20 years earlier for retinoblastoma and underwent a similar reconstruction.
  • The remaining four cases retained orbital volume and eyelid structures with a reasonable cosmetic outcome.
  • CONCLUSIONS: Eyelid- and conjunctiva-sparing orbital exenteration with temporalis transfer and dermis-fat graft is a useful technique that minimizes the usual deformity and achieves good results.
  • Case selection is emphasized, as this technique is mainly reserved for histopathologically benign orbital lesions that exhibit local aggressive behavior and for malignant lesions only if there is no eyelid, lacrimal gland, or orbital fissure involvement nor significant conjunctival or deep extension of an intraocular tumor.

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  • (PMID = 16418657.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Randriamora JT, Andrianilana H, Rarivomanana M, Raherizaka N, Rakotovao F, Rasoavelonoro VA: [Voluminous mucocele of frontal sinus with superior eyelid and orbit expansion]. J Fr Ophtalmol; 2005 Jan;28(1):55-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Voluminous mucocele of frontal sinus with superior eyelid and orbit expansion].
  • INTRODUCTION: A mucocele is an unusual benign cystic tumor, frequently seen in the adult and affecting mucous sinuses that expand the orbit by bone destruction.
  • DESCRIPTION: A 72-year-old man, without a history of sinus disease, presented a voluminous mucocele of the right frontal sinus that had begun 3 years before, with superior eyelid and orbit expansion hiding and pushing the eye to the downside and the outside.
  • After surgery, the patient recovered visual function without diplopia, and normal eyelid and ocular motility.
  • CONCLUSION: A mucocele of the frontal sinuses can show major superior eyelid development with a low risk of trochlea injury during surgery, a possibility particularly if the destruction of the anterior wall of the frontal sinuses is opened ahead of the orbit septum.

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  • (PMID = 15767900.001).
  • [ISSN] 0181-5512
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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18. Segal A, Segal N, Gal A, Tumuluri K: Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor. Orbit; 2010 Dec;29(6):334-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucinous sweat gland adenocarcinoma of the eyelid - current knowledge of a rare tumor.
  • PURPOSE: To review the medical literature on mucinous sweat gland adenocarcinoma of the eyelid (MSA) and present two new cases.
  • In 12(21.8%) patients a lesion with a benign diagnosis was previously excised from the same location.
  • In 2 of them histological re-examination resulted in a diagnosis of MSA.
  • Recurrence of the tumor was reported in 14(30%) patients.
  • CONCLUSIONS: MSA is a rare tumor of the eyelid with no clinically distinguishing features.
  • It should be suspected particularly with recurrent eyelid lesions and must be differentiated from metastatic disease.
  • The tumor may extend into the orbit and metastasize regionally.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Eyelid Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Mohs Surgery / methods. Neoplasm Staging. Rare Diseases. Risk Assessment. Treatment Outcome

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  • (PMID = 21158574.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
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19. Siepmann K, Wannke B, Neumann D, Rohrbach JM: Subcutaneous tumor of the lower eyelid: a potential manifestation of a Dirofilaria repens infection. Eur J Ophthalmol; 2005 Jan-Feb;15(1):129-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous tumor of the lower eyelid: a potential manifestation of a Dirofilaria repens infection.
  • PURPOSE: To report a case of Dirofilaria repens presenting as a subcutaneous tumor of the lower eyelid.
  • RESULTS: A 29-year-old man of Greek origin without systemic symptoms presented with a 3-week history of a small painless mass localized in the medial part of the lower eyelid.
  • CONCLUSIONS: Infection with the nematode Dirofilaria repens has to be considered in the differential diagnosis of malignant and benign tumors of subcutaneous periocular tissues in patients who traveled to endemic areas.
  • [MeSH-major] Dirofilaria / isolation & purification. Dirofilariasis / diagnosis. Eye Infections, Parasitic / diagnosis. Eyelid Diseases / diagnosis. Eyelid Neoplasms / diagnosis. Skin Diseases, Parasitic / diagnosis
  • [MeSH-minor] Adult. Animals. Diagnosis, Differential. Humans. Male

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  • (PMID = 15751252.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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20. Motegi S, Tamura A, Matsushima Y, Nagai Y, Ishikawa O: Squamous cell carcinoma of the eyelid arising from palpebral conjunctiva. Eur J Dermatol; 2006 Mar-Apr;16(2):187-9
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  • [Title] Squamous cell carcinoma of the eyelid arising from palpebral conjunctiva.
  • We reported a 58-year-old Japanese man with squamous cell carcinoma (SCC) of the left upper eyelid arising from the palpebral conjunctiva.
  • The tumor had been incised by a former doctor under the diagnosis of chalazion.
  • Histopathological examination of the relapsed tumor revealed atypical squamous cells invading towards the eyelid skin from the epithelium of palpebral conjunctiva.
  • We performed a total resection of the tumor and reconstructed the upper eyelid by the technique of Mustarde's switch flap.
  • SCC of the palpebral conjunctiva is quite rare, however, it often resembles chronic conjunctivitis or chalazion.
  • It is important to consider the possibility of SCC in addition to sebaceous carcinoma when we see a patient with an eyelid lesion, even one which looks like a benign condition such as chronic conjunctivitis or chalazion.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Conjunctiva. Eyelid Neoplasms / pathology

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  • (PMID = 16581575.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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21. Marback EF, Cardoso C, Moitinho LM, Marback RL: [Clinicopathologic study of eyelid pilomatrixoma: the experience of the "Hospital Universitário Prof. Edgard Santos"]. Arq Bras Oftalmol; 2007 May-Jun;70(3):501-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinicopathologic study of eyelid pilomatrixoma: the experience of the "Hospital Universitário Prof. Edgard Santos"].
  • [Transliterated title] Estudo clínico-patológico do pilomatrixoma palpebral: experiência no hospital universitário Prof. Edgard Santos.
  • PURPOSE: To report the experience with eyelid pilomatrixoma during 30 years in a university hospital.
  • METHODS: A review of the Ophthalmic Pathology Laboratory at the "Hospital Universitario Prof. Edgard Santos", was conducted to identify eyelid tumor cases from 1974 to 2004.
  • After identification of pilomatrixoma cases, a chart review retrieved data regarding gender, age, duration of symptoms, gross aspect, anatomic localization and clinical diagnosis.
  • RESULTS: Of a total of 621 eyelid tumors, four (0.64%) were pilomatrixomas.
  • The mean age at diagnosis was 25 years (from 8 to 54).
  • Only one patient had a correct clinical diagnosis.
  • CONCLUSION: This is a very rare benign tumor of young patients.
  • [MeSH-major] Eyelid Neoplasms / pathology. Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17768559.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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22. Arathi C, Vijaya C: Scrape cytology in the early diagnosis of eyelid sebaceous carcinoma. J Cytol; 2010 Oct;27(4):140-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scrape cytology in the early diagnosis of eyelid sebaceous carcinoma.
  • The low incidence and the non-specific clinical symptoms led us to conclude that the diagnosis of a sebaceous carcinoma of the eyelid often occurs very late.
  • Sebaceous carcinoma of the ocular adnexa is a malignant neoplasm which can exhibit aggressive local behavior, can have pagetoid spread and can metastasize to regional lymph nodes and distant organs.
  • The neoplasm is known to masquerade as other benign and less malignant lesions, and has relatively high morbidity and mortality.
  • Scrape cytology was done in a 70-year-old female with a tumor in left upper lid.
  • Subsequently, histopathology confirmed the diagnosis of sebaceous gland carcinoma.
  • The article highlights the role of scrape cytology in early diagnosis and subsequent appropriate surgical management of eyelid sebaceous gland carcinoma, to prevent recurrence and metastasis.

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  • (PMID = 21157566.001).
  • [ISSN] 0974-5165
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3001202
  • [Keywords] NOTNLM ; Sebaceous carcinoma / eyelid / scrape cytology
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23. Mathew S, Nandeesh BN, Vasu U, Michael SG: Neurothekeoma of the eyelid: a case report. Indian J Ophthalmol; 2008 Jul-Aug;56(4):334-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurothekeoma of the eyelid: a case report.
  • The purpose of this article is to describe a rare benign tumor of nerve sheath origin arising from the eyelid in an elderly male.
  • [MeSH-major] Eyelid Neoplasms / pathology. Neurothekeoma / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Humans. Male

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  • [Cites] J Cutan Pathol. 2003 Feb;30(2):118-22 [12641790.001]
  • [Cites] Jpn J Ophthalmol. 2004 Jan-Feb;48(1):78-79 [14767658.001]
  • [Cites] Am J Clin Pathol. 1980 Dec;74(6):759-64 [7446487.001]
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  • [Cites] Medicine (Baltimore). 1985 Jul;64(4):270-83 [4010501.001]
  • (PMID = 18579999.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2636171
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24. Varsori M, Dettwiler S, Chaloupka K: [Eyelid chondroid syringoma: a case report]. J Fr Ophtalmol; 2007 Jan;30(1):e3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Eyelid chondroid syringoma: a case report].
  • [Transliterated title] Syringome chondroïde de la paupière: à propos d'un cas.
  • Chondroid syringoma is a rare benign skin tumor of the head and neck.
  • Only 15 cases presenting on the eyelid have been described in the literature.
  • An 84-year-old patient presented with an 8-mm nodule on the right inferior eyelid that had grown over 5 years.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eyelid Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans

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  • (PMID = 17287665.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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25. Kumar S, Kumar S, Kulshrestha R: Cystic schwannoma of eyelid in an Indian male: a rare presentation. Orbit; 2008;27(6):407-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic schwannoma of eyelid in an Indian male: a rare presentation.
  • Eyelid schwannoma (neurilemmomas) is an extremely rare, benign neoplasm.
  • A case of Cystic Schwannoma in eyelid of a young adult is reported.
  • A 19-year-old male presented with a firm-nodular painless lesion, 3.5 cms in diameter, located on the left lower eyelid for the last 2 years.
  • Histopathological diagnosis of cystic schwannoma was made.
  • [MeSH-major] Cysts / pathology. Eyelid Neoplasms / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 19085294.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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26. Maheshwari R, Maheshwari S, Shekde S: Role of fine needle aspiration cytology in diagnosis of eyelid sebaceous carcinoma. Indian J Ophthalmol; 2007 May-Jun;55(3):217-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of fine needle aspiration cytology in diagnosis of eyelid sebaceous carcinoma.
  • Sebaceous carcinoma of the ocular adnexa is a malignant neoplasm which can exhibit aggressive local behavior and can metastasize to regional lymph nodes and distant organs.
  • The neoplasm is known to masquerade as other benign and less malignant lesions, resulting in delay in diagnosis and relative high morbidity and mortality.
  • Fine needle aspiration cytology (FNAC) of recurrent upper eyelid nodules treated elsewhere as chalazion was done.
  • Subsequently histopathology confirmed the diagnosis of sebaceous gland carcinoma.
  • Eyelid reconstruction was done after histopathologically confirmed tumor-free margins.
  • The article highlights the role of FNAC in early diagnosis and subsequent appropriate surgical management of eyelid sebaceous gland carcinoma to prevent recurrence and metastasis.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Biopsy, Fine-Needle. Eyelid Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged, 80 and over. Early Diagnosis. Female. Humans. Male. Middle Aged

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  • (PMID = 17456941.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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27. Reszec J, Sulkowski S: The expression of P53 protein and infection of human papilloma virus in conjunctival and eyelid neoplasms. Int J Mol Med; 2005 Oct;16(4):559-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The expression of P53 protein and infection of human papilloma virus in conjunctival and eyelid neoplasms.
  • The aim of this study was to evaluate P53 protein expression and to detect HPV in the tissue samples of 45 benign (papillomas) and 38 malignant conjunctival and eyelid lesions (27 basal cell carcinomas and 11 squamous cell carcinomas).
  • We also looked for eventual relationships between P53 expression and clinicopathological features such as age, histological type of tumor, grading and staging.
  • In the SCC and BCC groups, P53 was present in 31 out of 38 carcinomas and there was a statistically significant correlation between histological type of tumor and P53 protein expression.
  • P53 is probably involved in the development of conjunctival and eyelid tumors due to its high rate of presence in both benign and malignant neoplasms of these organs.
  • In some cases its role in the pathogenesis of conjunctival and eyelid tumorigenesis should be considered as auxiliary.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Eyelid Neoplasms / pathology. Papillomaviridae. Papillomavirus Infections / pathology. Tumor Suppressor Protein p53 / biosynthesis

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  • (PMID = 16142387.001).
  • [ISSN] 1107-3756
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
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28. Gündüz K, Demirel S, Heper AO, Günalp I: A rare case of atypical chondroid syringoma of the lower eyelid and review of the literature. Surv Ophthalmol; 2006 May-Jun;51(3):280-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of atypical chondroid syringoma of the lower eyelid and review of the literature.
  • A 46-year-old man presented with a painless firm mass in the eyelid margin of the left lower eyelid, which had been present for 9 years.
  • Biopsy nine years previously had not established a diagnosis.
  • We performed excisional biopsy of the lesion and lateral advancement skin flap for reconstruction of the skin defect.
  • Chondroid syringoma is a rare skin tumor that occurs, very rarely, in the eyelids, especially the lower eyelid.
  • The tumor can have benign, atypical, and malignant variants.
  • Our patient had the atypical variant, which is characterized by benign cytological features, as well as the presence of infiltrative margins and/or satellite nodules.
  • Even benign chondroid syringomas, if incompletely excised, can recur with malignant transformation; thus, complete excision and regular follow-up is recommended for all chondroid syringomas.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Eyelid Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged

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  • (PMID = 16644368.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Asadi Amoli F, Sina AH, Kasai A, Ayan Z: A well-known lesion in an unusual location: infantile myofibroma of the eyelid: a case report and review of literature. Acta Med Iran; 2010 Nov-Dec;48(6):412-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A well-known lesion in an unusual location: infantile myofibroma of the eyelid: a case report and review of literature.
  • Myofibroma is a neoplasia of myofibroblasts that can be solitary or multiple and it is found most commonly in the head & neck region including scalp, forehead, parotid region and oral cavity.
  • In the eyelid it is rarely reported.
  • It has a benign course in the solitary form and fatal in its multiple form.
  • A 4 month male infant referred to Farabi hospital -the referral center for eye diseases- with a 2 month history of a mass in his eyelid with gradual enlargement with no other complaints.
  • The only abnormal physical finding was a 2.5 cm mass in the eyelid.
  • Its pattern of growth and architecture rules out the other differential diagnoses like nodular fasciitis, fibrous histiocytoma, infantile fibromatosis, and peripheral primitive neuroectodermal tumor, mesenchymal chondrosarcoma, malignant hemangiopericytoma, juvenile fibrosarcoma and poorly differentiated synovial sarcoma.

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  • (PMID = 21287484.001).
  • [ISSN] 1735-9694
  • [Journal-full-title] Acta medica Iranica
  • [ISO-abbreviation] Acta Med Iran
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Iran
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30. Deprez M, Uffer S: Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol; 2009 May;31(3):256-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.
  • Eyelid tumors are the most common neoplasm in daily ophthalmology practice and encompass a wide variety of benign and malignant tumors.
  • In this retrospective study, we report the clinical and histological features of 5504 eyelid skin tumors diagnosed at the Laboratory of Ophthalmopathology of the Hôpital Ophtalmique Jules Gonin, Lausanne, Switzerland, between January 1989 and December 2007.
  • Benign tumors largely predominated over malignant ones, representing 84% of cases in this series, and the 5 most frequent subtypes were squamous cell papilloma (26%), seborrheic keratosis (21%), melanocytic nevus (20%), hidrocystoma (8%), and xanthoma/xanthelasma (6%).
  • Basal cell carcinoma was the most frequent malignant tumor (86%), followed by squamous cell carcinoma (7%) and sebaceous carcinoma (3%).
  • For several tumor subtypes, there was a poor correlation between clinical and histological diagnosis, stressing the numerous pitfalls in the diagnosis of eyelid tumors.
  • [MeSH-major] Eyelid Diseases / pathology. Eyelid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / pathology. Child. Child, Preschool. Female. Hidrocystoma / pathology. Humans. Infant. Keratosis, Seborrheic / pathology. Male. Middle Aged. Nevus, Pigmented / pathology. Papilloma / pathology. Predictive Value of Tests. Retrospective Studies. Sebaceous Gland Neoplasms / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Xanthomatosis / pathology. Young Adult

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  • (PMID = 19384066.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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31. Orzechowska-Wylegała B, Jedrzejewski P, Wylegała E, Steplewska K: Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report. Klin Oczna; 2008;110(7-9):301-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report.
  • Benign pleomorphic adenoma (mixed tumor) is the most frequently occurring tumor of epithelial origin.
  • In 1996, a 35 year old male patient underwent surgery to remove a tumor of the left orbit.
  • In 2005, from a cut along the upper-outer edge of the left orbit, an elastic and soft tumor 1 cm in diameter was removed from soft tissues of the upper eyelid.
  • An eyelid nodule of 0.8 mm in diameter was removed together with an elastic and hard tumor of size 2.5 x 1 cm.
  • The result of the histopathological examination of the palpebral tumor was pseudocystic tumor and of the orbital tumor was pleomorphic adenoma.

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  • (PMID = 19112866.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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32. Khong JJ, Chen CS, James CL, Huilgol SC, O'Donnell BA, Sullivan TJ, Selva D: Malignant fibrous histiocytoma of the eyelid: differential diagnosis and management. Ophthal Plast Reconstr Surg; 2005 Mar;21(2):103-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma of the eyelid: differential diagnosis and management.
  • The purpose of this study was to present a case series of periocular MFH and to discuss the differential diagnosis and management.
  • There were no distant metastases or tumor-related deaths.
  • CONCLUSIONS: This study highlights the difficulties in the clinicopathologic diagnosis of periocular MFH and in particular the distinction of more superficial tumors from atypical fibroxanthoma.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Eyelid Neoplasms / surgery. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Combined Modality Therapy. Diagnosis, Differential. Female. Humans. Lymphatic Metastasis. Male. Neoplasm Recurrence, Local. Ophthalmologic Surgical Procedures. Radiotherapy, Adjuvant. Retrospective Studies

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  • (PMID = 15778662.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Sokol JA, Clark JD, Lee HB, Nunery WR: Pigmented epithelioid melanocytoid tumor of the ocular adnexa. J Pediatr Ophthalmol Strabismus; 2010;47 Online:e1-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pigmented epithelioid melanocytoid tumor of the ocular adnexa.
  • An 8-year-old girl with a history of microphthalmia in the right eye presented with a left medial upper eyelid mass with a dark blue-green nodule that could be seen through the skin but did not appear to involve the overlying epidermis.
  • A biopsy demonstrated a pigmented epithelioid melanocytoid tumor with rare mitoses arising in association with a congenital nevus and positive margins.
  • Due to the pathological findings, the patient underwent excision of the tumor with 5-mm margins and a sentinel lymph node biopsy.
  • The re-excision of the upper eyelid margins demonstrated residual benign congenital melanocytic nevus, but did not reveal residual melanocytic lesion.
  • The parotid sentinel node biopsy revealed benign and cytologically mature nevus nests in the capsule and septa, but there was no evidence of involvement with the pigmented epithelioid melanocytoid tumor.
  • The patient underwent successful eyelid reconstruction and had no evidence of recurrence or metastasis after 2 years.
  • [MeSH-major] Eyelid Neoplasms / pathology. Nevus, Epithelioid and Spindle Cell / pathology. Skin Neoplasms / pathology

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 21162462.001).
  • [ISSN] 1938-2405
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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34. Wilde F, Neid M, Schulz T, Sterker I, Hemprich A, Frerich B: [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases]. Mund Kiefer Gesichtschir; 2005 Nov;9(6):404-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases].
  • [Transliterated title] Hämangioperizytom (extrapleuraler solitärer fibröser Tumor). Dargestellt und diskutiert anhand zweier Patientenbeispiele.
  • It is a very uncommon potentially malignant vascular tumour which can occur at every site of the body.
  • The diagnosis of "hemangiopericytoma" is now only determined if a constant histological picture of hemangiopericytoma is present.
  • The tumour can lead to lymphogenous or hematogenous metastasis.
  • CASE REPORTS: Patient 1: 60 years, female; diagnosis: malignant suboccipital hemangiopericytoma; size: 4.9 x 4.5 x 4.2 cm; pT1bNXMX L0 V0 Pn0; stage IA; grading G1; R0.Patient 2: 38 years, male; diagnosis: benign hemangiopericytoma infraorbital left; size 1.5 x 1.5 x 1.5 cm.
  • The slow and painless growth carries the danger of a clinically wrong diagnosis and thus delayed therapy.
  • The histological diagnosis of hemangiopericytoma is determined by biopsy.
  • The therapy of choice is the complete tumour-resection with a safety margin of 1 cm.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangiopericytoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Orbit / pathology. Orbital Neoplasms / diagnosis. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Reoperation. Tomography, X-Ray Computed

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  • [Cites] Langenbecks Arch Surg. 2000 Apr;385(3):207-12 [10857492.001]
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  • (PMID = 16220316.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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35. Hałoń A, Błazejewska M, Sabri H, Rabczyński J: [Tumors and tumor-like lesions of eyelids collected at Department of Pathological Anatomy, Wroclaw Medical University, between 1946 and 1999]. Klin Oczna; 2005;107(7-9):475-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tumors and tumor-like lesions of eyelids collected at Department of Pathological Anatomy, Wroclaw Medical University, between 1946 and 1999].
  • PURPOSE: To determine the histopathological, epidemiological and clinical characteristics of benign, malignant and tumor-like lesions of the eyelid collected in Department of Pathological Anatomy, Wrocław Medical University.
  • MATERIAL AND METHODS: Department of Pathological Anatomy, Wrocław Medical University, has been collecting data of all tumors and tumor-like lesions of the eye and ocular adnexa diagnosed at the department during the 54-year interval from 1946 through 1999.
  • Retrospective analysis of all eyelid biopsy specimens submitted to the department between January 1, 1946, and December 31, 1999 were performed.
  • The incidence cohort of all eyelid lesions included 2031 cases what made up 42.15% of all diagnosed lesions within the eye and it's adnexa.
  • Benign tumors were the most common lesions (n=1262; 62.2%).
  • Malignant tumors developed most commonly on the lower eyelid (n=303; 70%) but involved the right and left sides with equal frequency.
  • Almost 2/3 of all tumor-like lesions in both genders were cysts including atheromas.
  • CONCLUSIONS: Benign eyelid tumors compose the majority of all eyelid lesions.
  • Basal cell carcinoma is the most common malignant eyelid tumor.
  • The lower eyelid is the most frequent site of origin in cases of malignant tumors.
  • [MeSH-major] Carcinoma / epidemiology. Eyelid Neoplasms / epidemiology. Papilloma / epidemiology

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  • (PMID = 16417001.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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36. Leoncini G, Maio V, Puccioni M, Franchi A, De Giorgi V, Ucci F, Santucci M, Massi D: Orbital solitary fibrous tumor: a case report and review of the literature. Pathol Oncol Res; 2008 Jun;14(2):213-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital solitary fibrous tumor: a case report and review of the literature.
  • Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm typically arising in the pleura and involving the orbit as its most common extra-pleural location.
  • We herein describe a well documented case of orbital SFT arising in a 62-year-old woman presenting with progressive swelling of the right upper eyelid and proptosis.
  • The tumor had a benign clinical course, with radical surgical excision followed by regression of the clinical symptoms.
  • We review the clinical, histopathological, and immunohistochemical features of the orbital SFT described so far, with particular emphasis on differential diagnosis with other spindle cell orbital neoplasms.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / surgery. Solitary Fibrous Tumors / diagnosis. Solitary Fibrous Tumors / surgery
  • [MeSH-minor] Diagnosis, Differential. Exophthalmos / etiology. Female. Humans. Immunohistochemistry. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18493869.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 26
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37. Zembowicz A, Garcia CF, Tannous ZS, Mihm MC, Koerner F, Pilch BZ: Endocrine mucin-producing sweat gland carcinoma: twelve new cases suggest that it is a precursor of some invasive mucinous carcinomas. Am J Surg Pathol; 2005 Oct;29(10):1330-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is an underrecognized low-grade carcinoma with predilection to the eyelid.
  • The most common site of occurrence was the lower eyelid (8 cases).
  • Two lesions occurred on the upper eyelid and 2 on the cheek.
  • Calponin, smooth muscle actin, and p63 immunohistochemical stains did not disclose myoepithelial cells around larger tumor nests in most cases, supporting the notion that EMPSGC is an invasive carcinoma.
  • In 10 cases, cystic areas lined by benign epithelium indistinguishable from eccrine ducts were present.
  • In some foci, the benign ductal epithelium was undermined or replaced by carcinoma in situ with similar cytologic features to the solid or papillary areas of EMPSGC.
  • The series provides histologic evidence for a multistage progression of noninvasive sweat gland neuroendocrine carcinoma to EMPSGC and then to mucinous carcinoma of the eyelid.
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Cheek / pathology. Eyelid Neoplasms / metabolism. Eyelid Neoplasms / pathology. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 16160476.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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38. Kim HJ, McCormick SA, Nath S, Moskowitz B, Milman T: Melanocytic nevi of the tarsal conjunctiva: clinicopathologic case series with review of literature. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):438-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathology revealed combined nevi centered in the posterior lamella of the eyelid, predominantly in peri-Meibomian gland distribution.
  • Adult presentation; subjective and objective evidence of growth; and associated inflammation, vascularity, and eyelid margin changes may make clinical distinction of tarsal nevi from melanoma challenging.
  • Biopsy, therefore, is prudent as histopathology alone allows documentation of the benign nature of these lesions.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Eyelid Neoplasms / pathology. Nevus, Pigmented / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Child, Preschool. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 20683369.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • The rarity of the tumour makes its diagnosis and management a challenge.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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40. Decock CE, Kataria S, Breusegem CM, Van Den Broecke CM, Claerhout IJ: Ectopic meningioma anterior to the lacrimal gland fossa. Ophthal Plast Reconstr Surg; 2009 Jan-Feb;25(1):57-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 66-year-old man reported a slowly growing tumor on the lateral edge of his left upper eyelid.
  • A neoplasm of the lacrimal gland was suspected.
  • CT showed a highly calcified lesion at the left upper eyelid.
  • Resection of the tumor was performed, which was located just behind the orbital septum and in front of the lacrimal gland.
  • Anatomopathologic investigation of the excised specimen with immunohistochemistry revealed a benign meningioma of a meningotheliomatous type, containing multiple bone elements.
  • Therefore, it should be included in the differential diagnosis of a lacrimal gland tumor.

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  • (PMID = 19273931.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucin-1; 0 / Vimentin
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41. Adenis JP, Sabatier A, Robert PY: [Tumors of the eyelids in the elderly]. J Fr Ophtalmol; 2006 Jun;29(6):687-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Les tumeurs des paupières des personnes âgées.
  • The clinical aspect of tumors of the eyelids is polymorphous; however, the most frequent are benign tumors such as papillomas, basal cell carcinoma, squamous cell carcinoma, meibomian gland carcinoma, and melanomas.
  • For the most malignant tumors such as malignant melanoma and Merkel cell tumor, lymph sentinel biopsy is a recent, valuable tool, but its benefit needs to be confirmed in large series.
  • [MeSH-major] Eyelid Neoplasms / diagnosis

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  • (PMID = 16885901.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 13
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42. Chanfi M: [Tuberous angioma in an infant: a case study]. J Fr Ophtalmol; 2005 Sep;28(7):774
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tuberous angioma of the orbit is the most frequent benign tumor of the orbit in children.
  • The author reports the clinical observation of a giant tuberous angioma the entire left lower eyelid radiating throughout the left cheek of a 2-month-old infant.
  • [MeSH-major] Eyelid Neoplasms. Hemangioma

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  • (PMID = 16208215.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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43. George JL, Marchal JC: [Orbital tumors in children: clinical examination, imaging, specific progression]. Neurochirurgie; 2010 Apr-Jun;56(2-3):244-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Les tumeurs d'orbite de l'enfant : examen clinique, paraclinique, diagnostic et particularités évolutives.
  • Benign tumors such as dermoid cysts or hemangiomas grow slowly, whereas rapid growth suggests a malignant tumor.
  • The general examination focuses especially on cutaneous abnormalities such as café au lait spots and subcutaneous nodules in neurofibromatosis type 1 (NF1), a hemangioma that often involves the cutaneous portion of the eyelid.
  • When a metastatic tumor is suspected, abdominal palpation and ultrasonography must be performed.
  • Most of the time, standard x-rays, CT, and MR imaging allow for an adequate assessment and usually provide a diagnosis.
  • [MeSH-major] Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adult. Age Factors. Child. Disease Progression. Emotions. Exophthalmos / etiology. Humans. Leukemia / diagnosis. Leukemia / epidemiology. Leukemia / pathology. Neoplasm Metastasis / pathology. Neuroblastoma / diagnosis. Neuroblastoma / epidemiology. Neuroblastoma / pathology. Palpation. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / epidemiology. Rhabdomyosarcoma / pathology

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20303555.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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44. Garnacho Saucedo GM, Moreno Jiménez JC, Jiménez Puya R, Rodríguez Bujaldon A: Therapeutic Hotline: Topical glycopyrrolate: a successful treatment for craniofacial hyperhidrosis and eccrine hidrocystomas. Dermatol Ther; 2010 Jan-Feb;23(1):94-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eccrine hidrocystoma is a benign tumor derived from eccrine sudoriparous glands.
  • [MeSH-major] Eyelid Neoplasms / drug therapy. Glycopyrrolate / therapeutic use. Hidrocystoma / drug therapy. Hyperhidrosis / drug therapy. Muscarinic Antagonists / therapeutic use. Sweat Gland Neoplasms / drug therapy

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  • (PMID = 20136914.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Muscarinic Antagonists; V92SO9WP2I / Glycopyrrolate
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45. Bajaj MS, Pushker N, Kashyap S, Sen S, Vengayil S, Chaturvedi A: Fibrous histiocytoma of the lacrimal gland. Ophthal Plast Reconstr Surg; 2007 Mar-Apr;23(2):145-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fibrous histiocytoma, a primary mesenchymal tumor of the orbit, is known to arise from various ocular and adnexal tissues.
  • We are unable to find a published report of this tumor originating from the lacrimal gland.
  • We report a case of a benign fibrous histiocytoma of the lacrimal gland in an 11 year old girl who presented with painless, progressive eyelid swelling and mild proptosis.
  • The tumor was completely excised by anterolateral orbitotomy.
  • Light microscopy showed a spindle cell tumor arising from the lacrimal gland.
  • The tumor cells were arranged in a characteristic storiform (cartwheel) pattern with no pleomorphism or mitotic figures.
  • Immunohistochemically, the tumor cells were focally positive for CD-68 and negative for S-100, smooth muscle actin, vimentin, and CD-34, which ruled out neurofibroma, leiomyoma, solitary fibrous tumor, and hemangiopericytoma.
  • Based on these features, a diagnosis of benign fibrous histiocytoma was made.
  • [MeSH-major] Eye Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Lacrimal Apparatus Diseases / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Child. Female. Humans. Neoplasm Proteins / analysis. Tomography, X-Ray Computed

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  • (PMID = 17413632.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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46. Perlmann E, da Silva EG, Guedes PM, Barros PS: Co-existing squamous cell carcinoma and hemangioma on the ocular surface of a cat. Vet Ophthalmol; 2010 Jan;13(1):63-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Upon microscopic examination, a malignant epithelial neoplasm and a benign vascular neoplasm were present in the cornea.
  • The conjunctiva and the third eyelid were also affected.
  • Upon immunohistochemistry, the epithelial tumor was positive for cytokeratin and negative for vimentin and the endothelial tumor was negative for cytokeratin and positive for vimentin.
  • A diagnosis of squamous cell carcinoma (SCC) and hemangioma was made.
  • The SCC was affecting the cornea, bulbar conjunctiva (lateral and inferior) and the base of the third eyelid, whereas the hemangioma was affecting the cornea and medial limbus.

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  • (PMID = 20149179.001).
  • [ISSN] 1463-5224
  • [Journal-full-title] Veterinary ophthalmology
  • [ISO-abbreviation] Vet Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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47. Chen CC, Chang YT, Liu HN: Clinical and histological characteristics of poroid neoplasms: a study of 25 cases in Taiwan. Int J Dermatol; 2006 Jun;45(6):722-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Eccrine poroma (EP) are relatively common benign eccrine neoplasms.
  • Other poroid neoplasms (PNs), namely hidroacanthoma simplex (HS), dermal duct tumor (DDT), and poroid hidradenoma (PH), are seldom reported.
  • Histopathologically, it is not justified to exclude PN diagnosis by noticing horn cysts.
  • [MeSH-major] Skin Neoplasms / pathology. Sweat Gland Diseases / pathology
  • [MeSH-minor] Aged. Biopsy. Eyelid Neoplasms / pathology. Female. Humans. Male. Middle Aged. Necrosis. Taiwan

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  • (PMID = 16796636.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Winn BJ, Herreid PA, Sires BS: Intravenous pyogenic granuloma of the angular vein. Ophthal Plast Reconstr Surg; 2009 Jul-Aug;25(4):341-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe the CT profile of this rare, benign tumor as a mildly heterogeneic, contrast-enhancing cylindrical lesion within, and conforming to the shape of, the angular vein.
  • [MeSH-major] Eyelid Diseases / diagnosis. Granuloma, Pyogenic / diagnosis. Lacrimal Apparatus / blood supply. Vascular Diseases / diagnosis. Veins
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Ophthalmologic Surgical Procedures / methods. Tomography, X-Ray Computed

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  • (PMID = 19617809.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • CASE REPORT: A 57-year-old woman presented with a 16-month history of a slowly growing mass in the medial aspect of her right lower eyelid.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.
  • It is important to consider it preoperatively because the vascular nature of this tumour may create problems with hemostasis during excision.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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50. Kazakov AA, Grishina EE, Tarantul VZ, Gening LV: Effect of human cell malignancy on activity of DNA polymerase iota. Biochemistry (Mosc); 2010 Jul;75(7):905-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To clarify the possible role of incorrect DNA polymerase iota (Pol iota) function in increased frequency of mutations in mammalian cells, the activity of this enzyme in extracts of cells of different mouse organs and human eye (melanoma) and eyelid (basal-cell skin carcinoma) tumor cells was studied.
  • In the presence of Mn2+ the Pol iota activity in the basal-cell carcinoma exceeded 2.5-fold that in control cells (benign tumors from the same eyelid region).
  • In extracts of melanoma cells in the presence of either cation, the level of the enzyme activity was approximately equal to that in extracts of cells of surrounding tumor-free tissues as well as in eyes removed after traumas.
  • [MeSH-minor] Animals. Cell Line, Tumor. Enzyme Activation / drug effects. Enzyme Activators / pharmacology. Humans. Magnesium / pharmacology. Manganese / pharmacology. Mice. Mice, Inbred C57BL. Mutation

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  • (PMID = 20673215.001).
  • [ISSN] 1608-3040
  • [Journal-full-title] Biochemistry. Biokhimii︠a︡
  • [ISO-abbreviation] Biochemistry Mosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Enzyme Activators; 42Z2K6ZL8P / Manganese; EC 2.7.7.- / DNA polymerase iota; EC 2.7.7.7 / DNA-Directed DNA Polymerase; I38ZP9992A / Magnesium
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51. Stone DU, Chodosh J: Epibulbar nodular fasciitis associated with floppy eyelids. Cornea; 2005 Apr;24(3):361-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSIONS: Nodular fasciitis is a rare, benign, soft-tissue tumor that has not been previously reported in association with floppy eyelids.
  • [MeSH-major] Eyelid Diseases / diagnosis. Eyelids / pathology. Fasciitis / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 15778617.001).
  • [ISSN] 0277-3740
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Zheng JW, Wang YA, Zhou GY, Zhu HG, Ye WM, Zhang ZY: [Head and neck hemangiomas: how and when to treat]. Shanghai Kou Qiang Yi Xue; 2007 Aug;16(4):337-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangiomas are common benign vascular tumors of infancy characterized by a proliferative growth phase followed by very slow inevitable regression (involutive phase) between one to ten years of age, about 60% to 70% of the lesions are found in the head and neck region.
  • For larger and deeper hemangiomas up to a depth of 2.0 cm, percutaneous interstitial Nd:YAG laser treatment may be preferred, because it may decrease possible cutaneous skin damage and more effectively reduce bulky, deep lesion. (5) Topical application of imiquimoid and intratumoral injection of steroids or bleomycin can be used in selected patients with rapidly growing hemangioma. (6) The indication for a primary operation is rare and limited to large hemangiomas in the eyelid or hemangiomas on the scalp.
  • A successful treatment of hemangiomas should be individualized and based on the size of the tumor, the localization, and the therapies available.

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  • (PMID = 17924011.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] China
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53. Cashell AW: Apocrine adenoma of the breast. W V Med J; 2008 Mar-Apr;104(2):16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A case of apocrine adenoma, a rare benign tumor of the breast is reported.
  • The tumor was well circumscribed and composed of tightly packed tubules lined by cells with apocrine features.
  • Apocrine adenomas have been reported arising in a variety of sites including the breast, (1-5) perianal region, (6,7) eyelid, (8) and axilla. (9) Their appearance has similarities to the apocrine metaplasia commonly seen in fibrocystic change of the breast but they are well-circumscribed tumors with closely packed tubular and papillary structures.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Breast Neoplasms / diagnosis
  • [MeSH-minor] Biopsy, Needle. Diagnosis, Differential. Female. Humans. Mammography. Middle Aged. Ultrasonography, Mammary

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  • (PMID = 18491794.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Abalo-Lojo JM, Cameselle-Teijeiro J, Gonzalez F: Pilomatrixoma: late onset in two periocular cases. Ophthal Plast Reconstr Surg; 2008 Jan-Feb;24(1):60-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • First described by Malherbe and Chenantais in 1880, pilomatrixoma is a benign skin neoplasm that arises from hair follicle matrix cells.
  • It is typically a tumor of younger individuals and rarely presents in older patients.
  • [MeSH-major] Eyelid Neoplasms / pathology. Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 18209650.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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55. Robinson JW, Brownstein S, Jordan DR, Hodge WG: Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature. Surv Ophthalmol; 2006 Sep-Oct;51(5):513-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Invasive mucoepidermoid carcinoma of the conjunctiva of the left lower eyelid was diagnosed in an orbital exenteration specimen of a 57-year-old woman, after a biopsy of the same lesion was originally diagnosed as invasive squamous cell carcinoma.
  • The woman was undergoing mitomycin C injections for ocular cicatricial pemphigoid, diagnosed in the same eye 2 years prior to identification of the neoplasm.
  • The tumor invaded the cornea, sclera, lacrimal gland, regional small nerves, and lymphatics, but did not show intraocular involvement.
  • [MeSH-major] Carcinoma, Mucoepidermoid / pathology. Conjunctival Neoplasms / pathology. Conjunctivitis / complications. Pemphigoid, Benign Mucous Membrane / complications
  • [MeSH-minor] Basement Membrane / pathology. Biopsy. Drug Therapy, Combination. Female. Fluorometholone / therapeutic use. Humans. Middle Aged. Mitomycin / therapeutic use. Neoplasm Invasiveness. Ofloxacin / therapeutic use


56. Dutton JJ, Wright JD Jr: Intramuscular lipoma of the superior oblique muscle. Orbit; 2006 Sep;25(3):227-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe a rare intramuscular infiltrating lipomatous tumor affecting the superior oblique muscle.
  • A 37-year-old female presented with eyelid swelling, proptosis and motility disturbance.
  • Biopsy showed an infiltrative tumor consisting of adipocytes with included degenerated muscle fibers.
  • Histologic features were consistent with a benign intramuscular lipoma, rather than the more aggressive well-differentiated liposarcoma.
  • A review of the literature found three previously described periorbital cases, two in the eyelid, and one in the anterior orbit.
  • Enlargement of an extraocular or periorbital muscle with a low-density infiltrating lesion should raise suspicion for this unusual tumor.

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  • (PMID = 16987771.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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57. Lavaju P, Arya SK, Sinha A, Pandey S, Adhikari S, Shrestha BG, Chetan S, Agarwal TL: Pattern of ocular tumors in the eastern region of Nepal. Nepal J Ophthalmol; 2009 Jan-Jun;1(1):9-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: the hospital records of patients with ocular tumors treated at B P Koirala Institute of Health Sciences in the eastern region of Nepal over a period of 5 years (April 2003 - March 2008) were studied retrospectively.
  • There were 48 (41.73%) and 67 (58.26%) patients with benign and malignant tumors respectively.
  • The common benign tumors were conjunctival papilloma, dermoid cysts, nevus, cystic lesions and hemangioma.
  • Retinoblastoma was the most common ocular malignant tumor in the pediatric age group (88.8%).
  • Basal cell carcinoma was the commonest eyelid malignancy (53.57%).
  • CONCLUSION: conjunctival papilloma, dermoid cysts, nevus, cystic lesions and hemangioma are common benign ocular tumors, whereas basal cell carcinoma and retinoblastoma are the commonest ocular malignancies in adults and children respectively.

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  • (PMID = 21141015.001).
  • [ISSN] 2072-6805
  • [Journal-full-title] Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
  • [ISO-abbreviation] Nepal J Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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58. Kashkouli MB, Khalatbari MR, Yahyavi T, Borghei Razavi H, Shayanfar N, Parvaresh MM: Primary endo-orbital osteoid osteoma. Orbit; 2008;27(3):211-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteiod osteoma is a small, benign, osteoblastic tumor, which usually affects the long bone of the lower extremities and vertebrae.
  • A 22-year-old man presented with eyelid edema, proptosis and pain in the left eye 1 year after the beginning of the symptoms.
  • [MeSH-minor] Adult. Biopsy, Needle. Exophthalmos / diagnosis. Exophthalmos / etiology. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18569832.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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59. Fonseca Junior NL, Cha SB, Cartum J, Rehder JR: [Therapeutical effectiveness of interferon alpha in a child with craniofacial giant hemangioma: case report]. Arq Bras Oftalmol; 2008 May-Jun;71(3):423-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Eficácia terapêutica do interferon alfa em criança com hemangioma gigante craniofacial: relato de caso.
  • Hemangiomas are the most common benign tumors of infancy.
  • The diagnosis of these tumors is based on physical examination.
  • This is a case of a patient with three months of age, that presented since birth, a purplish tumor in the superior eyelid of the right eye, plain and purplish cutaneous lesions in the temporal and parietal right region.

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  • (PMID = 18641835.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Interferon-alpha
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60. Finn M, Krohne S, Stiles J: Ocular melanocytic neoplasia. Compend Contin Educ Vet; 2008 Jan;30(1):19-25; quiz 26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ocular melanocytic neoplasia.
  • Tumors of melanocytic origin in ocular tissues are relatively uncommon in dogs and cats, and although many are benign, some have a high potential for metastasis.
  • While several similarities exist among these tumors, the prognosis and recommended treatment options vary based on the species affected as well as the location, extent, and histologic characteristics of the tumor.
  • This article reviews the clinical presentation, biologic behavior, and treatment options for eyelid, conjunctival, limbal (epibulbar), and uveal tumors of melanocytic origin in dogs and cats.
  • [MeSH-major] Cat Diseases / diagnosis. Dog Diseases / diagnosis. Eye Neoplasms / veterinary. Melanoma / veterinary

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  • (PMID = 18278744.001).
  • [ISSN] 1940-8315
  • [Journal-full-title] Compendium (Yardley, PA)
  • [ISO-abbreviation] Compend Contin Educ Vet
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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61. Soong T, Soong V, Salvi SM, Raynor M, Mudhar H, Goel S, Edwards M: Primary corneal myxoma. Cornea; 2008 Dec;27(10):1186-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myxomas occur commonly in other soft tissues such as the heart, paranasal sinuses, and muscles but can rarely present in periocular structures including the conjunctiva, orbit, and eyelid.
  • These include an inferonasal location between the corneal epithelium and Bowman layer and with no relationship to the corneal stroma, rapid tumor growth over a 3-month period, and no previous ocular trauma or conjunctival pathology.
  • The histology of this lesion has an important part to play in the management of this condition as it determines the cellular origin, establishes a benign or malignant state, and helps with treatment and prognosis.

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  • (PMID = 19034139.001).
  • [ISSN] 1536-4798
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Rodrigues EB, Shields CL, Eagle RC Jr, Marr BP, Shields JA: Solitary intraosseous orbital myofibroma in four cases. Ophthal Plast Reconstr Surg; 2006 Jul-Aug;22(4):292-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To report four pediatric cases of a bone-destructive orbital tumor that proved to be a benign solitary intraosseous myofibroma.
  • METHODS: Four children, aged 1, 7, 11, and 72 months, developed eyelid fullness or slight proptosis.
  • The diagnosis was also supported by immunohistochemical studies showing positive immunoreactivity for vimentin and smooth muscle actin.
  • CONCLUSIONS: Myofibroma is a benign tumor that can occur in the orbital bony wall of children.

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  • (PMID = 16855503.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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63. Belliveau MJ, Brownstein S, Jordan DR, Faraji H: Low-grade, aggressive fibrous histiocytoma of the medial canthus. Can J Ophthalmol; 2008 Apr;43(2):250

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-grade, aggressive fibrous histiocytoma of the medial canthus.

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  • (PMID = 18347642.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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