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1. Al-Ahwal MS, Sawan AS, Zimmo SK: Malignant eccrine poroma. Saudi Med J; 2005 May;26(5):859-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant eccrine poroma.
  • Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct.
  • We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletely excised, followed 5 months later by local recurrence, ulceration, occasional bleeding and right inguinal lymphadenopathy.
  • Incomplete excision of the primary tumor as well as excision of a skin lesion on the right knee joint revealed malignant eccrine poroma with aggressive histology, lymphovascular and perineural invasion.
  • This tumor might be malignant at the first presentation, which was not confirmed histopathologically considering the short duration of only 5 months for malignant transformation.
  • The management of metastatic malignant eccrine poroma is difficult.
  • It has proven resistant to many chemotherapeutic agents and radiotherapy.

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  • [CommentIn] Saudi Med J. 2005 Oct;26(10):1665; author reply 1665 [16228085.001]
  • (PMID = 15951884.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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2. Yildirim S, Aköz T, Akan M, Ege GA: De novo malignant eccrine spiradenoma with an interesting and unusual location. Dermatol Surg; 2001 Apr;27(4):417-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] De novo malignant eccrine spiradenoma with an interesting and unusual location.
  • BACKGROUND: Reports in the literature reveal that malignant eccrine spiradenomas (MES) are exceedingly rare, and represent aggressive tumors arising in long-standing benign eccrine spiradenomas (ES).
  • OBJECTIVE: We present a de novo case of MES of the nose, in contrast to reports in the literature of progression from long-standing benign lesions.
  • RESULTS: Our case was accepted as de novo MES because there was no evidence of ES on pathologic examination.
  • It was treated by surgical excision with 1 cm tumor-free margins.
  • CONCLUSION: Although previously reported lesions have arisen in long-standing benign ESs, usually on the trunk or extremities, this report shows that MES may occur as a primary malignant tumor and may occur in unusual locations such as the nose.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / secondary. Colonic Neoplasms / secondary. Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary. Male. Middle Aged. Neoplasms, Multiple Primary

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  • (PMID = 11298720.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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