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1. Medina EA, Arias VL: [Middle ear adenoma]. Biomedica; 2009 Sep;29(3):348-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma].
  • [Transliterated title] Adenoma del oído medio.
  • Middle ear neoplasms are rare lesions and difficult to diagnose due to limited information about their biology and the lack of standard criteria for their analysis.
  • Herein, a middle ear neoplasm is described that became apparent because of its appearance in the external ear duct as it protruded from the middle ear through the eardrum.
  • Following resection, the specimen was determined to be a benign epithelial tumor.
  • Absence of adequate clinical information complicated the diagnosis; therefore,histochemistry and immunohistochemistry analyses were necessary to reach the final diagnosis of middle ear adenoma.
  • [MeSH-major] Adenoma. Ear Neoplasms. Ear, Middle

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  • (PMID = 20436986.001).
  • [ISSN] 0120-4157
  • [Journal-full-title] Biomédica : revista del Instituto Nacional de Salud
  • [ISO-abbreviation] Biomedica
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Colombia
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2. Bakari A, Afolabi OA, Adoga AA, Kodiya AM, Ahmad BM: Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria. BMC Res Notes; 2010;3:186

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria.
  • The aim of this study is to evaluate the clinico-pathological profile of sinonasal masses in our environmentThis is a retrospective analytical review of all the patients with sinonasal masses that presented to the national ear care center, Kaduna over a six year (2003-2008) period.
  • About 59 (77.6%) were benign, 2 (2.6%) were malignant and 15 (19.7%) were lost to follow up.
  • CONCLUSIONS: Nasal obstruction and rhinorrhea are the commonest symptoms of presentation, simple inflammatory nasal polyp is still the commonest histological pattern seen in our environment, and surgery is still the best modality of treatment for benign tumor thus the need for advocacy for early recognition and referral to the ENT surgeon.

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  • (PMID = 20618972.001).
  • [ISSN] 1756-0500
  • [Journal-full-title] BMC research notes
  • [ISO-abbreviation] BMC Res Notes
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2916008
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3. Saliba I, Evrard AS: Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. Cases J; 2009;2:6508

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series.
  • INTRODUCTION: Middle ear glandular neoplasms are infrequent causes of a middle ear mass.
  • Herein, we present a new case of a middle ear glandular neoplasm.
  • Our objective is to review all cases described in the literature in order to identify the clinical features, the gross pathology, the histopathology, the immunohistochemistry, to discuss the differential diagnosis, the treatment, the rate of recurrence, the follow-up, the incidence of metastasis, the prognosis and to present a new classification of middle ear glandular neoplasm.
  • RESULTS: Ninety-four patients with a middle ear adenoma are included in this report.
  • We uncovered 75 patients with a carcinoid tumor and 19 patients with a middle ear adenoma diagnosis; the most common presenting symptom was a conductive hearing loss.
  • Middle ear adenomas are lesions that are typically white, gray or reddish brown.
  • The tumor's cells are immunohistochemically positive for a variety of keratin antibodies and most of them are also positive for neuroendocrine markers.
  • CONCLUSIONS: Our study and the review of the literature showed adenomas and carcinoid tumors of the middle ear to be essentially indistinguishable benign tumors with metastatic potential.

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  • (PMID = 20111612.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2812983
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4. Lim JH, Jono H, Koga T, Woo CH, Ishinaga H, Bourne P, Xu H, Ha UH, Xu H, Li JD: Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PLoS One; 2007 Oct 10;2(10):e1032
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.
  • The deubiquitinating enzyme cylindromatosis (CYLD), loss of which was originally reported to cause a benign human syndrome called cylindromatosis, has been identified as a key negative regulator for NF-kappaB in vitro.
  • Our data demonstrated that CYLD is induced by NTHi in the middle ear and lung of mice.

  • MedlinePlus Health Information. consumer health - Haemophilus Infections.
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  • (PMID = 17925880.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC004562; United States / NIDCD NIH HHS / DC / R01 DC005843; United States / NIDCD NIH HHS / DC / DC004562; United States / NIDCD NIH HHS / DC / DC005843
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / NF-kappa B; 0 / TNF Receptor-Associated Factor 6; 0 / TRAF7 protein, human; 0 / Traf7 protein, mouse; 0 / Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; EC 3.1.2.15 / CYLD protein, mouse; EC 3.4.22.- / Cysteine Endopeptidases
  • [Other-IDs] NLM/ PMC2001183
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5. Rydzewski B, Goździcka-Józefiak A, Sokalski J, Matusiak M, Durzyński L: [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms]. Otolaryngol Pol; 2007;61(2):137-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms].
  • There's a hypothesis, that it plays a significant role in middle ear chronic inflammations and neoplasm's.
  • The examination was carried on a group of 53 patients, 39 of which was suffering from granulation tissue chronic otitis media, 7-cholesteatomatous otitis media, 6--middle ear malignant neoplasm, and 1 middle and/or external ear benign neoplasm.
  • The material was postoperative tissue, like polyps, inflammatory granulation tissue, cholesteatoma masses and malignant neoplasm's tissue.
  • In every case of middle ear malignant neoplasm a presence of high-risk DNA Papilloma types 16 or 18 was confirmed.
  • CONCLUSIONS: The results has been compared with other authors examinations and it is claimed that they confirm the observation, that Human Papilloma Viruses may be a factor, that might play an important role in pathology of chronic otitis media and ear neoplasm's.
  • It is concluded, that differences in percentages of HPV presence in chronic inflammations (70%) and ear neoplasm's may be explained by viral co-infection during bacterial c. o. m.
  • [MeSH-major] Ear / virology. Ear Neoplasms / virology. Papilloma / genetics. Papilloma / virology. Papillomavirus Infections / diagnosis. Tumor Virus Infections / diagnosis. Tumor Virus Infections / virology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Cholesteatoma, Middle Ear / epidemiology. Cholesteatoma, Middle Ear / virology. Female. Humans. Male. Middle Aged. Otitis Media / epidemiology. Otitis Media / virology. Poland / epidemiology. Polymerase Chain Reaction. Prognosis

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  • (PMID = 17668798.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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6. Dalit A, Karen M, Alexander M: Congenital desmoid tumor of the cheek: a clinicopathological case report. Eplasty; 2009;9:e52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital desmoid tumor of the cheek: a clinicopathological case report.
  • OBJECTIVE: Desmoid tumors are rare benign neoplasms of fibroblastic origin, frequently presenting in the abdomen of adult patients.
  • METHODS: We report a girl with a desmoid tumor of her cheek, which was present at birth.
  • RESULTS: The tumor was treated by surgical excision, with no additional treatment, other than follow-up.
  • No recurrence of the tumor was witnessed 15 months following surgical excision.
  • SUMMARY: Radical surgical treatment with tumor excision, sometimes accompanied by radiotherapy, is the current standard therapy for infantile desmoid tumors.

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  • (PMID = 20011031.001).
  • [ISSN] 1937-5719
  • [Journal-full-title] Eplasty
  • [ISO-abbreviation] Eplasty
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2779781
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7. Strehl MA, Scheich M, Ott I, Müller-Hermelink HK, Hagen R, Völker HU: [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?]. Laryngorhinootologie; 2009 Mar;88(3):186-90
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?].
  • [Transliterated title] Mittelohradenom/Mittelohrkarzinoid--ein unproblematischer Tumor?
  • OBJECTIVES: Adenomas/carcinoid tumors of the middle ear are very rare tumors of young to middle aged patients.
  • The terms adenoma and carcinoid tumor of the middle ear can be used as synonyms, with the WHO favouring the term middle ear adenoma (MEA).
  • They are classified as benign tumors with only very few reported cases of regional metastasis after years of disease.
  • METHODS AND PATIENTS: This study describes the clinical course and the diagnostic challenges in four cases of this rare tumor entity.
  • In two cases a tumor recurrence was documented with one case recurring six times.
  • CONCLUSION: Adenomas of the middle ear can have a much more complicated clinical course than is suggested by the recent literature.
  • The presented cases in this study and the analysis of previously published cases shows that the typical progression described by the current WHO-classification with unproblematic surgical management of the tumor and an uncomplicated further clinical course does not always correspond to reality.
  • [MeSH-major] Adenoma / diagnosis. Carcinoid Tumor / diagnosis. Ear Neoplasms / diagnosis. Ear, Middle
  • [MeSH-minor] Adult. Cholesteatoma, Middle Ear / diagnosis. Cholesteatoma, Middle Ear / pathology. Cholesteatoma, Middle Ear / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / surgery. Otoscopy. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 19065497.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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8. Prasad K, Rao SG, Harish K: Giant cell tumor of the temporal bone--a case report. BMC Ear Nose Throat Disord; 2005 Sep 15;5:8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cell tumor of the temporal bone--a case report.
  • BACKGROUND: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull.
  • The petrous portion of the temporal bone forms a rare location for this tumor.
  • CASE PRESENTATION: The authors report a case of a large giant cell tumor involving the petrous and squamous portions of the temporal bone in a 26 year old male patient.
  • Radical excision of the tumor was achieved but facial palsy could not be avoided.
  • CONCLUSION: Radical excision of skull base giant cell tumor may be hazardous but if achieved is the optimal treatment and may be curative.

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  • (PMID = 16162299.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1253509
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9. Czerny C, Nemec S, Krestan C, Gstöttner W: [Benign and malignant lesions in the region of the inner ear and cerebellopontine angle]. Radiologe; 2006 Mar;46(3):197-204

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign and malignant lesions in the region of the inner ear and cerebellopontine angle].
  • [Transliterated title] Benigne und maligne Veränderungen der Innenohr- und Kleinhirnbrückenwinkelregion.
  • Tumorous lesions in the region of the inner ear and cerebellopontine angle are very rare and can be classified into benign and malignant disease forms.
  • The coronary slices can be reconstructed from the axial datasets or in individual cases examined in the coronary plane.HRCT excellently demonstrates osseous lesions and in individual cases - e.g., exostoses - it can simply suffice to perform HRCT of the temporal bone, while HRCT is also excellent for detecting osseous lesions to determine whether the tumor is benign or malignant.MRI, on the other hand, excellently shows the extent of tumor spread because of its superb soft tissue contrast.
  • Consequently, HRCT and MRI images of the inner ear and cerebellopontine angle provide meaningful information for visualization and classification of tumorous lesions.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle / diagnostic imaging. Cerebellopontine Angle / pathology. Ear Neoplasms / diagnosis. Ear, Inner / diagnostic imaging. Ear, Inner / pathology

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  • [Cites] Acta Neurochir (Wien). 2002 Oct;144(10):1047-53 [12382133.001]
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  • (PMID = 16418859.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 23
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10. Saruya S, Nagamine H, Komiya T, Ito S, Iino Y, Kodera K, Imamura T: [Immunohistochemical and clinical features of patients with benign middle ear tumors]. Nihon Jibiinkoka Gakkai Kaiho; 2007 May;110(5):403-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Immunohistochemical and clinical features of patients with benign middle ear tumors].
  • The middle ear is a rare site for benign tumors.
  • We report six patients with benign middle ear tumors surgicaly removed: three with carcinoid, one with adenoma, and two with paraganglioma.
  • [MeSH-major] Adenoma / pathology. Carcinoid Tumor / pathology. Ear Neoplasms / pathology. Ear, Middle. Paraganglioma / pathology

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  • (PMID = 17564130.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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11. Zehlicke T, Punke C, Boltze C, Pau HW: Transient facial palsy in two cases of benign, very rare middle ear tumors (carcinoid tumor and myxoma). Neurologist; 2008 Jan;14(1):52-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transient facial palsy in two cases of benign, very rare middle ear tumors (carcinoid tumor and myxoma).
  • OBJECTIVE: Presentation of the clinical features of 2 very rare middle ear tumors in which the guiding symptom was facial palsy.
  • MATERIAL AND METHODS: Illustrative case reports about a myxoma and a carcinoid tumor of the middle ear associated with peripheral facial palsy.
  • Moreover, both tumor entities are typically found in organs other than the ear; if located in the middle ear, those neoplasms grow rather superficially.
  • In those cases, a surgical exposure of the middle ear is indicated.
  • We report the cases of 2 rare middle ear tumors causing facial palsy.
  • [MeSH-major] Carcinoid Tumor / pathology. Ear Neoplasms / pathology. Ear, Middle / pathology. Facial Paralysis / pathology. Myxoma / pathology

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  • (PMID = 18195660.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Ferlito A, Devaney KO, Rinaldo A: Primary carcinoid tumor of the middle ear: a potentially metastasizing tumor. Acta Otolaryngol; 2006 Mar;126(3):228-31
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  • [Title] Primary carcinoid tumor of the middle ear: a potentially metastasizing tumor.
  • The concept of a carcinoid tumor in the gastrointestinal tract and lung is well established; less often, patients develop carcinoid tumors in the head and neck region.
  • One particularly uncommon site of origin of carcinoid tumors in the head and neck area is the middle ear.
  • Middle ear carcinoids have previously been approached as benign entities, lacking any capacity for metastasizing.
  • A critical review of the literature, however, disclosed a small number of cases in which middle ear carcinoid tumors have given rise to regional (cervical node) metastases.
  • This in turn suggests that, as is the case with pulmonary carcinoid tumors, middle ear carcinoids should be thought of as low-grade malignancies which, while relatively slow-growing, nevertheless possess a limited capacity for spreading to regional lymph nodes.
  • To date, distant metastases have not been associated with middle ear carcinoid tumors.
  • [MeSH-major] Carcinoid Tumor / secondary. Ear Neoplasms / pathology. Ear, Middle. Lymphatic Metastasis / pathology. Neoplasm Invasiveness / pathology
  • [MeSH-minor] Biopsy, Needle. Female. Humans. Immunohistochemistry. Male. Neoplasm Staging. Prognosis. Risk Assessment. Survival Rate. Treatment Outcome

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  • (PMID = 16618645.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Norway
  • [Number-of-references] 21
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13. Emodi O, El-Naaj IA, Gordin A, Akrish S, Peled M: Superficial parotidectomy versus retrograde partial superficial parotidectomy in treating benign salivary gland tumor (pleomorphic adenoma). J Oral Maxillofac Surg; 2010 Sep;68(9):2092-8
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  • [Title] Superficial parotidectomy versus retrograde partial superficial parotidectomy in treating benign salivary gland tumor (pleomorphic adenoma).
  • PURPOSE: Of all benign salivary gland tumors of the parotid gland, pleomorphic adenoma (mixed tumor) is the most common.
  • It accounts for 60% to 70% of all benign tumors of the parotid gland.
  • This neoplasm arises in patients in the fourth to sixth decade of life, with a female predominance.
  • The purpose of our study is to compare 2 surgical techniques performed at the Ear, Nose, and Throat and Maxillofacial Departments, Rambam Medical Center, Haifa, Israel, and determine which is preferable in treating this lesion.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Oral Surgical Procedures / methods. Parotid Gland / surgery. Parotid Neoplasms / surgery

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  • [Copyright] Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20728030.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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14. Sumi T, Tsunoda A, Shirakura S, Kishimoto S: Mechanical obstruction of the eustachian tube by the benign tumor of the parapharyngeal space does not cause otitis media with effusion. Otol Neurotol; 2007 Dec;28(8):1072-5
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  • [Title] Mechanical obstruction of the eustachian tube by the benign tumor of the parapharyngeal space does not cause otitis media with effusion.
  • OBJECTIVE: We are reporting on eustachian tube and middle ear pathologic findings in patients with parapharyngeal tumors.
  • PATIENTS: Eleven cases of eustachian tube involvement as indicated by obstruction due to compression of the tumor were assessed in this study.
  • RESULTS: All of the tumors were diagnosed benign according to the histologic examination.
  • In 9 of the 11 patients, the pharyngeal opening of the eustachian tube narrowed or was blocked by the tumor.
  • None of the patients showed any response on the tumor side in the sonotubometry.
  • Therefore, gas exchange was prevented through the eustachian tube by the tumor; however, they also showed an intact tympanic membrane and normal hearing tests.
  • CONCLUSION: According to our data, if there is drainage of middle ear fluid through the eustachian tube and the exchange of gas in the middle ear is preserved, otitis media with effusion will not occur even in cases such as these.
  • [MeSH-major] Adenoma / complications. Eustachian Tube. Otitis Media with Effusion / etiology. Pharyngeal Neoplasms / complications
  • [MeSH-minor] Acoustic Impedance Tests. Adult. Audiometry, Pure-Tone. Ear, Middle / physiology. Female. Functional Laterality / physiology. Humans. Magnetic Resonance Imaging. Nasopharynx / pathology. Otoscopy. Tomography, X-Ray Computed. Tympanic Membrane / physiology

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  • (PMID = 18084819.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Berns S, Pearl G: Middle ear adenoma. Arch Pathol Lab Med; 2006 Jul;130(7):1067-9
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  • [Title] Middle ear adenoma.
  • Middle ear adenoma is a benign tumor of the middle ear that can have exocrine (mucinous) and/or neuroendocrine differentiation.
  • Early authors described a separate tumor with predominantly neuroendocrine differentiation as a middle ear carcinoid tumor, but these are now known to be the same tumor.
  • We review the literature of this tumor, including the clinical presentation, gross pathology, histopathology, immunohistochemistry, differential diagnosis, and prognosis.
  • [MeSH-major] Adenoma / pathology. Ear Neoplasms / pathology. Ear, Middle
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry / methods. Neurilemmoma / diagnosis. Papilloma / diagnosis. Paraganglioma / diagnosis. Prognosis

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  • (PMID = 16831038.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 11
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16. Wiatr M, Składzień J: [Benign tumors of the external and middle ear from data collected at the Otolaryngologyst Department of the Jagiellonian University in Cracow between 1992-2001]. Przegl Lek; 2007;64(12):1004-5

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  • [Title] [Benign tumors of the external and middle ear from data collected at the Otolaryngologyst Department of the Jagiellonian University in Cracow between 1992-2001].
  • [Transliterated title] Nowotwory łagodne ucha zewnetrznego i środkowego w materiale Kliniki Otolaryngologii CM UJ w Krakowie w latach 1992-2001.
  • 26 patients with benign tumors of the external and middle ear were treated at the Otolaryngology Department of the Jagiellonian University in Cracow between 1992-2001.
  • Benign tumors of the external and middle ear are rare diseases, and it is usually easy to establish final diagnosis.
  • In our population the most common tumor was osteoma located in external ear canal.
  • [MeSH-major] Ear Neoplasms / surgery. Ear, External / surgery. Ear, Middle / surgery. Osteoma / surgery

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  • (PMID = 18595503.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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17. Olszewski J, Konopka W, Radek A, Zieliński K, Pietkiewicz P: [Middle ear schwannoma--case report]. Otolaryngol Pol; 2005;59(6):907-10
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  • [Title] [Middle ear schwannoma--case report].
  • [Transliterated title] Schwannoma ucha środkowego--opis przypadku.
  • Schwannoma is one of the common benign middle ear space tumors.
  • The tumors may present with facial nerve paresis or palsy, otologic symptoms and/or parotid mass middle ear schwannomas may originate from the nerves of the tympanic caviti or by extensions from outside the middle ear space.
  • The patient underwent middle ear exploration and mastoidectomy.
  • The tumor was of facial nerve origin and was separated from middle ear.
  • [MeSH-major] Ear Neoplasms / pathology. Ear, Middle / pathology. Neurilemmoma / pathology

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  • (PMID = 16521463.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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18. Bogomilsky MR, Turusov DA, Kushel IuV, Zelikovich EI, Poliaev IuA: [Glomus tumors of the middle ear in children]. Vestn Otorinolaringol; 2007;(5):4-7
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  • [Title] [Glomus tumors of the middle ear in children].
  • Glomus tumor (GT) is a rare tumor of the middle ear in children.
  • In spite of cytologically benign nature of this tumor, its course can be characterized as malignant because of GT infiltrative growth, destruction of the adjacent bone tissue, possible intracranial involvement.
  • At admission to hospital principal complaints of the children are poor hearing, discharge from the ear.
  • GT of the middle ear are detected with application of computed tomography which is able to show changes in the soft tissue and bone destruction, and angiography.
  • GT treatment planning depends on the examination data and can include radiotherapy, endovascular occlusion of the vessels carrying blood to the tumor, surgical treatment and combination of the methods.
  • [MeSH-major] Ear Neoplasms / epidemiology. Ear Neoplasms / pathology. Ear, Middle / pathology. Glomus Tumor / epidemiology. Glomus Tumor / pathology

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  • (PMID = 18163069.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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19. Zehlicke T, Punke C, Haase K, Boltze C, Pau HW: [Myxoma of the middle ear-a rare cause of facial palsy]. HNO; 2008 Feb;56(2):165-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Myxoma of the middle ear-a rare cause of facial palsy].
  • [Transliterated title] Das Myxom des Mittelohrs als mögliche Ursache einer temporären Fazialisparese.
  • In case of the co-occurrence of facial palsy and inflammation-like symptoms of the same ear, the differential diagnosis is focused on viral (herpes zoster) or bacterial diseases.
  • We report a patient for whom the surgical exploration of the middle ear revealed a benign tumor: a myxoma.
  • These neoplasias are rare tumors in the head and neck region.
  • The typical tumor site is the atrium of heart.
  • In the ear, the tumor grows slowly and remains asymptomatic unless it irritates structures such as the facial nerve or the vestibular organ.
  • Histologically, the tumor presents a "myxoid" matrix that is rich in acid mucopolysaccarides.
  • Using the case presented, we discuss the causality between the tumor and the facial palsy, although during the operation the bony canal of the nerve was found to be intact.
  • In any cases with clinically and radiologically unclear findings of the ear in connection with facial palsy, surgical exposure should be considered.
  • [MeSH-major] Ear Neoplasms / complications. Ear, Middle. Facial Paralysis / etiology. Myxoma / complications

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  • [Cites] HNO. 1969 Apr;17 (4):113-5 [5405595.001]
  • [Cites] Head Neck. 1996 Sep-Oct;18(5):459-64 [8864738.001]
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  • (PMID = 17115088.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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20. Kojima H, Yaguchi Y, Moriyama H: Middle ear hemangiona: a case report. Auris Nasus Larynx; 2008 Jun;35(2):255-9
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  • [Title] Middle ear hemangiona: a case report.
  • A middle ear hemangioma was detected in a 51-year-old man who suffered from fullness and hearing loss in the left ear.
  • The mass was surgically resected for diagnostic and therapeutic reasons, and pathologic examination revealed a benign hemangioma.
  • The CT, MRI, angiography, and light microscopy findings of the tumor are documented and compared with those a glomus tumor.
  • [MeSH-major] Ear Neoplasms / diagnosis. Ear, Middle. Hemangioma / diagnosis

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  • (PMID = 17851004.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 16
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21. Tubbs RS, Kelly DR, Pugh JL, Loukas M, Oakes WJ: Benign fibrous histiocytoma of the skull base. Case report. J Neurosurg; 2007 Jan;106(1 Suppl):65-7
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  • [Title] Benign fibrous histiocytoma of the skull base. Case report.
  • The authors report the case of benign fibrous histiocytoma (BFH) of the skull base in an 11-month-old girl.
  • During draining for a middle ear infection, the child was noted to have an anomalous mass in the skull base.
  • At the most recent follow-up examination--18 months postoperatively--the child was noted to be asymptomatic with no gross increase in tumor size.
  • [MeSH-major] Histiocytoma, Benign Fibrous / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Female. Follow-Up Studies. Humans. Infant. Occipital Bone / pathology. Occipital Bone / surgery. Temporal Bone / pathology. Temporal Bone / surgery

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  • (PMID = 17233317.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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22. Angouridakis N, Hytiroglou P, Markou K, Bouzakis A, Vital V: Middle ear adenoma/carcinoid tumour: a case report and review of the literature. Rev Laryngol Otol Rhinol (Bord); 2009;130(3):199-202
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Middle ear adenoma/carcinoid tumour: a case report and review of the literature.
  • Middle ear adenoma, a rare benign tumour with glandular and neuroendocrine differentiation, originates from the epithelial lining of the middle ear.
  • CASE REPORT: We report a case of a 52-year-old woman, who presented with progressive hearing loss and fullness in the left ear for 3 months.
  • Clinical examination revealed a mass in the left middle ear.
  • CONCLUSION: Middle ear adenoma is a benign tumour that is treated by complete surgical removal.
  • The immunohistochemical staining of the present case supports the suggestion that this tumour is best described by the term neuroendocrine adenoma of the middle ear.
  • [MeSH-major] Adenoma. Carcinoid Tumor. Ear Neoplasms. Ear, Middle

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  • (PMID = 20345079.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 17
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23. Kloek CE, Bilyk JR, Pribitkin EA, Rubin PA: Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex. Ophthalmology; 2006 Jul;113(7):1214-9
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  • [Title] Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex.
  • The purpose of this study was to investigate outcomes in 5 patients with benign-appearing but symptomatic tumors located in the intraconal portion of the orbital apex in which orbital decompression was performed as an alternative management strategy to resection.
  • PARTICIPANTS: Five patients were diagnosed with a compressive optic neuropathy secondary to a benign-appearing tumor at the orbital apex.
  • None of the patients had the tumor biopsied or resected.
  • CONCLUSIONS: Orbital decompression is a therapeutic option for patients with compressive optic neuropathies from benign orbital apex tumors, offering potential improvement in optic nerve function while sparing morbidity from attempts at surgical resection.
  • [MeSH-major] Decompression, Surgical. Nerve Compression Syndromes / surgery. Optic Nerve Diseases / surgery. Orbit / surgery. Orbital Neoplasms / surgery

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  • [CommentIn] Ophthalmology. 2007 Mar;114(3):619-20; author reply 620-1 [17324707.001]
  • (PMID = 16815404.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Sanna M, Fois P, Pasanisi E, Russo A, Bacciu A: Middle ear and mastoid glomus tumors (glomus tympanicum): an algorithm for the surgical management. Auris Nasus Larynx; 2010 Dec;37(6):661-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Middle ear and mastoid glomus tumors (glomus tympanicum): an algorithm for the surgical management.
  • OBJECTIVE: Glomus tumors are slow-growing benign lesions and represent the most common primary neoplasms of the middle ear.
  • METHODS: Between December 1988 and July 2008, 68 patients with histologically confirmed glomus tympanicum tumor underwent surgical treatment.
  • Nineteen patients with larger Class B tumors underwent a subtotal petrosectomy with blind sac closure of the external auditory canal and middle ear obliteration.
  • Gross total tumor removal was achieved in all 68 cases.
  • CONCLUSION: Surgical excision of glomus tympanicum tumors is a safe procedure, allowing total tumor removal with minimal morbidity, a low recurrence rate, and a low complication rate.
  • [MeSH-major] Algorithms. Ear Neoplasms / surgery. Ear, Middle. Glomus Tympanicum Tumor / surgery. Mastoid. Skull Neoplasms / surgery. Surgical Procedures, Operative
  • [MeSH-minor] Adult. Aged. Audiometry. Female. Follow-Up Studies. Hearing Loss / diagnosis. Hearing Loss / etiology. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Otologic Surgical Procedures. Postoperative Period. Reoperation. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome. Tympanic Membrane Perforation / etiology. Young Adult

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  • [Copyright] Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20400250.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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25. Sciarretta V, Pasquini E, Frank G, Modugno GC, Cantaroni C, Mazzatenta D, Farneti G: Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases. Am J Rhinol; 2006 Jan-Feb;20(1):64-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases.
  • BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma.
  • METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively.
  • The endoscopic approach was simple in 28 cases and associated with an external approach in 5 cases (because of an intracranial extension of the tumor in four patients and its location at the level of the anterior wall of the frontal sinus in the last case).
  • CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.
  • [MeSH-major] Endoscopy / methods. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 16539297.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Okada K, Ito K, Yamasoba T, Ishii M, Iwasaki S, Kaga K: Benign mass lesions deep inside the temporal bone: imaging diagnosis for proper management. Acta Otolaryngol Suppl; 2007 Dec;(559):71-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mass lesions deep inside the temporal bone: imaging diagnosis for proper management.
  • CONCLUSION: Among mass lesions inside the temporal bone, benign tumors and cholesteatomas can be differentiated by contrast enhancement in T1-weighted images (T1WI) and by diffusion-weighted images (DWI).
  • RESULTS: One patient had facial schwannoma, two had glomus jugulare tumor, and three had cholesteatoma.
  • MRI study provided us with better clues: contrast enhancement on T1WI was observed only in benign tumors and only cholesteatomas showed high intensity on DWI.
  • [MeSH-major] Cholesteatoma, Middle Ear. Cranial Nerve Neoplasms / diagnosis. Cranial Nerve Neoplasms / surgery. Facial Nerve. Glomus Jugulare Tumor / diagnosis. Granuloma / diagnosis. Granuloma / surgery. Mucocele / diagnosis. Neurilemmoma / diagnosis. Neurilemmoma / surgery. Temporal Bone

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  • (PMID = 18340574.001).
  • [ISSN] 0365-5237
  • [Journal-full-title] Acta oto-laryngologica. Supplementum
  • [ISO-abbreviation] Acta Otolaryngol Suppl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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27. Zhi KQ, Deng PF, Ren WH, Zhang L, Li XQ, Wen YM: [A clinical retrospective study on modified parotidectomy in benign tumors of parotid gland]. Shanghai Kou Qiang Yi Xue; 2008 Jun;17(3):229-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A clinical retrospective study on modified parotidectomy in benign tumors of parotid gland].
  • Tumor size, blood loss, operating time, temporary facial paralysis, tumour recurrence were compared between the two groups.
  • RESULTS: There was no significant difference between the two groups in tumor size, temporary facial paralysis and tumor recurrence.
  • CONCLUSIONS: The modified parotidectomy is a function-preserving surgery for benign parotid tumours, which improves the cosmetics, the feeling around ear, reduces the duration of surgery, and the incidence rate of Frey's syndrome.
  • [MeSH-minor] Ear Auricle. Face. Facial Paralysis. Humans. Postoperative Complications. Retrospective Studies. Sweating, Gustatory

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  • (PMID = 18661059.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] China
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28. Vo QT, Wolf JA, Turner JW, Murkis M, Saw D, Shemen LJ: Solitary fibrous tumor of the parapharyngeal space. Ear Nose Throat J; 2007 Aug;86(8):502-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the parapharyngeal space.
  • Solitary fibrous tumors are benign neoplasms of mesenchymal origin.
  • We report a case of solitary fibrous tumor of the parapharyngeal space.
  • Microscopically, the tumor contained spindle cells with areas of marked hypercellularity without a definitepattern.
  • Consistent with a benign lesion, there were few mitoses and no necrosis.
  • The tumor cells stained strongly positive for CD34 and vimentin.
  • [MeSH-major] Hemangiopericytoma / pathology. Hemangiopericytoma / surgery. Neoplasms, Fibrous Tissue / pathology. Neoplasms, Fibrous Tissue / surgery. Otorhinolaryngologic Surgical Procedures / methods. Pharyngeal Neoplasms / pathology. Pharyngeal Neoplasms / surgery

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  • (PMID = 17915675.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V: Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol; 2008 Mar-Apr;29(2):142-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review.
  • INTRODUCTION: Primary neoplasms of the external ear canal are rare, and 5% of these tumors are of glandular origin.
  • Ceruminal glands are modified sweat glands of the skin of the external auditory meatus that may give rise to (a) benign tumors such as ceruminous adenoma, pleomorphic adenoma, and syringocystadenoma papilliferum, and (b) malignant tumors such as ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma.
  • An alternative theory holds that pleomorphic adenomas may well arise from ectopic salivary tissue present in the external ear canal.
  • These tumors are very rare and usually have a benign course.
  • In this report, we describe an unusual case of pleomorphic adenoma of the external auditory canal associated with chronic infection of the middle ear.
  • She had been affected with chronic otitis media and aural polyps for the last 13 years, for which she had received medical treatment only.
  • A canal-filling aural polyp was noted on clinical examination.
  • Subsequent biopsy and histologic examination revealed pleomorphic adenoma of the external ear canal, possibly with malignant elements.
  • The patient underwent modified radical mastoidectomy and complete resection of the tumor and the entire skin of the external auditory canal.
  • CONCLUSIONS: Pleomorphic adenoma is an extremely rare tumor arising from the ceruminal glands of the external ear canal.
  • Nonspecific presentation and difficult histologic diagnosis characterize this benign neoplasm.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear, External / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 18314029.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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30. Schrock A, Gutgemann I, Keiner S: [Castleman's disease in ear, nose, and throat practice]. HNO; 2007 May;55 Suppl 1:E29-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Castleman's disease in ear, nose, and throat practice].
  • Castleman's disease, also called angiofollicular lymph node hyperplasia or benign giant lymphoma, is a rare lymphoproliferative disorder of unknown etiology.
  • Due to the lack of tumor-specific clinical, biochemical, and radiological features, final diagnosis of Castleman's disease depends on histopathology.
  • Surgical tumor resection is the treatment of choice for localized disease.
  • Therefore, early invasive removal and histopathological differentiation from neoplasia is mandatory.
  • On admission, the patient complained of a painless pharyngeal tumor mass and ipsilateral lymph node swelling.
  • After tumor resection, histopathological examination, and clinical staging, localized Castleman's disease was diagnosed (hyaline vascular subtype).
  • [MeSH-major] Giant Lymph Node Hyperplasia / diagnosis. Giant Lymph Node Hyperplasia / surgery. Otolaryngology / methods. Pharyngeal Neoplasms / diagnosis. Pharyngeal Neoplasms / surgery

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  • [Cites] Am J Hematol. 2002 Feb;69(2):119-26 [11835348.001]
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  • (PMID = 17262216.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 16
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31. Ren WH, Zhi KQ, Gao L, Xu Y, Li XQ, Shi MJ: [Clinical utilization of veiled incision and sternocleidomastoid flap in parotidectomy of parotid benign tumors]. Shanghai Kou Qiang Yi Xue; 2010 Jun;19(3):232-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical utilization of veiled incision and sternocleidomastoid flap in parotidectomy of parotid benign tumors].
  • There was no significant difference between these two groups in temporary facial paralysis, salivary fistula, tumor recurrence, Frey's syndrome, the feeling of the region around the auricular lobule.
  • [MeSH-minor] Ear Auricle. Face. Humans. Neoplasms. Parotid Neoplasms. Postoperative Complications. Surgical Flaps

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  • (PMID = 20635029.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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32. Kiverniti E, Cilasun U, Singh A, Kazi R, Clarke PM, Archer DJ: Aggressive fibromatosis of the oropharynx: a multidisciplinary approach to a benign disease. Ear Nose Throat J; 2009 May;88(5):930-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive fibromatosis of the oropharynx: a multidisciplinary approach to a benign disease.
  • We discuss the characteristics of this rare tumor and review the literature, stressing the importance of postoperative follow-up for peritonsillar abscesses to avoid missing other important diagnoses, such as the one described here.
  • [MeSH-major] Fibromatosis, Aggressive / pathology. Oropharynx / pathology. Palatal Neoplasms / pathology

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  • (PMID = 19444791.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Keleş E, Akpolat N, Alpay HC, Tazegül A: [A rare tumor in a newborn: congenital epulis]. Kulak Burun Bogaz Ihtis Derg; 2005;14(3-4):92-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A rare tumor in a newborn: congenital epulis].
  • Congenital epulis is a benign tumor.
  • [MeSH-major] Gingival Diseases / diagnosis. Gingival Neoplasms / diagnosis

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  • (PMID = 16227732.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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34. Shekarkhar MJ, Tabei SZ, Kumar PV, Hashemi SB: Cytologic findings in calcifying epithelial odontogenic tumor: a case report. Acta Cytol; 2005 Sep-Oct;49(5):533-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic findings in calcifying epithelial odontogenic tumor: a case report.
  • BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT), or Pindborg's tumor, is a rare, benign, odontogenic neoplasm first described by Pindborg in 1955.
  • CASE: A 62-year-old woman was referred to the ear, nose and throat clinic with a right maxillary mass.
  • CONCLUSION: FNA findings of calcifying epithelial odontogenic tumor have been described rarely.
  • The clusters of epithelial cells with prominent nucleoli are mistaken for features of a malignant tumor.
  • [MeSH-major] Calcinosis / pathology. Epithelial Cells / pathology. Jaw Neoplasms / pathology. Maxillary Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology. Palatal Neoplasms / pathology

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  • (PMID = 16334032.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Izadi F, Azizi MR, Ghanbari H, Kadivar M, Pousti B: Angiomyxoma of the larynx: case report of a rare tumor. Ear Nose Throat J; 2009 Jul;88(7):E11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyxoma of the larynx: case report of a rare tumor.
  • Laryngeal spindle cell neoplasms are uncommon tumors, frequently misdiagnosed as reactive lesions or mesenchymal malignancies.
  • One of the rare mesenchymal tumors of the larynx is myxoid spindle cell tumor (angiomyxoma), a benign proliferative lesion.
  • Although benign, angiomyxomas have a propensity for local recurrence due to their tendency to infiltrate surrounding tissues.
  • They commonly appear encapsulated, but simple enucleation does not provide adequate treatment; excision should include a margin of normal tissue around the tumor.
  • The tumor in our case showed no histologic evidence of aggressive behavior, but because of the potential for local recurrence, close follow-up was warranted.
  • [MeSH-major] Laryngeal Neoplasms. Myxoma

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  • (PMID = 19623517.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Kuczkowski J, Izycka-Swieszewska E, Plichta Ł, Cieszyńska J: [Combined tumor of ceruminous gland origin in the external auditory canal--a histopathological and immunohistochemical study]. Otolaryngol Pol; 2010 Nov-Dec;64(6):385-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Combined tumor of ceruminous gland origin in the external auditory canal--a histopathological and immunohistochemical study].
  • OBJECTIVES: We present a case of a combined tumor consisting of solid tubular gland adenoma (TA) and syringocystadenoma papilliferum (SCAP) of the external auditory canal and review of the literature on this subject.
  • CONCLUSIONS: Tubular gland adenoma and syringocystadenoma papilliferum are benign tumors originating from ceruminous glands of the skin, characterized by very rare occurrence especially in the skin of the external auditory canal.
  • Every tumor arising from the external auditory canal should be examined histologically and immunohistochemically in order to choose the best treatment option.
  • [MeSH-major] Adenoma / pathology. Cerumen. Ear Neoplasms / pathology. Ear, External / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor. Female. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 21302507.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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37. Cheung FM, Lau TW, Cheung LK, Li AS, Chow SK, Lo AW: Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV. Ear Nose Throat J; 2010 Oct;89(10):E5-E12
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV.
  • Schneiderian papillomas are uncommon benign tumors of the sinonasal area.
  • For each case, we documented the morphology, immunohistochemical expression of tumor suppressor genes p53 and p16, and any association with human papillomavirus (HPV) infection as detected by either polymerase chain reaction or in situ hybridization techniques.
  • [MeSH-major] Genes, p16 / physiology. Genes, p53 / physiology. Nasal Mucosa. Nose Neoplasms / pathology. Papilloma / pathology

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  • (PMID = 20981655.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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38. Pérez-Guillermo M, Acosta-Ortega J, García-Solano J, Ramos-Freixá J: Cytologic aspect of brown tumor of hyperparathyroidism. Report of a case affecting the hard palate. Diagn Cytopathol; 2006 Apr;34(4):291-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic aspect of brown tumor of hyperparathyroidism. Report of a case affecting the hard palate.
  • The cytologic and histologic findings of one brown tumor (BT) of hyperparathyroidism located in the hard palate, at first misdiagnosed as peripheral giant-cell granuloma, are described.
  • Poor communication between cytopathologist and ear nose and throat specialist was responsible for the error.
  • MGC-rich aspirates pose the same diagnostic dilemmas as those of histologic sections of MGC-containing lesions of bone: these cells are not diagnostic by themselves and can be seen in several benign and malignant conditions.
  • [MeSH-major] Hyperparathyroidism / complications. Hyperparathyroidism / pathology. Jaw Neoplasms / pathology. Palate, Hard / pathology

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  • (PMID = 16544338.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Sadetzki S, Chetrit A, Freedman L, Stovall M, Modan B, Novikov I: Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis. Radiat Res; 2005 Apr;163(4):424-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis.
  • Our aims were to assess the risk of radiation-induced malignant brain tumors and benign meningiomas after childhood exposure and to investigate the role of potential modifiers of that risk.
  • Survival analysis using Poisson regression was performed to estimate the excess relative and absolute risks (ERR, EAR) for brain tumors.
  • After a median follow-up of 40 years, an ERR/Gy of 4.63 and 1.98 (95% CI = 2.43-9.12 and 0.73-4.69) and an EAR/Gy per 10(4) PY of 0.48 and 0.31 (95% CI = 0.28-0.73 and 0.12-0.53) were observed for benign meningiomas and malignant brain tumors, respectively.
  • The estimated ERR/Gy for malignant brain tumors decreased with increasing age at irradiation from 3.56 to 0.47 (P = 0.037), while no trend with age was seen for benign meningiomas.
  • The ERR for both types of tumor remains elevated at 30-plus years after exposure.
  • [MeSH-major] Brain / radiation effects. Brain Neoplasms / epidemiology. Neoplasms, Radiation-Induced / epidemiology. Radiotherapy / statistics & numerical data. Risk Assessment / methods. Tinea Capitis / epidemiology. Tinea Capitis / radiotherapy


40. Onal C, Yuksel O, Topkan E, Pehlivan B: Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report. Cases J; 2009;2:8402

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report.
  • INTRODUCTION: Glomus tumors are benign, slow growing tumors originating from paraganglionic tissue, mostly located at the carotid bifurcation, jugular foramen, cervical portion vagus nerve, and middle ear cavity.
  • CASE PRESENTATION: We present a 53-year-old female patient with a glomus tumor treated with positron emission tomography computed tomography planning and 3D conformal radiotherapy, and the patient has remained free of disease progression 2 years after.
  • CONCLUSION: It is suggested that radiotherapy is a good treatment modality in patients with glomus tumor, and metabolic imaging and treatment planning with positron emission tomography computed tomography is superior to other imaging modalities.

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  • (PMID = 19918426.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769436
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41. Bambakidis NC, Rodrigue T, Megerian CA, Ratcheson RA: Endolymphatic sac tumor metastatic to the spine. Case report. J Neurosurg Spine; 2005 Jul;3(1):68-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endolymphatic sac tumor metastatic to the spine. Case report.
  • Although histologically benign, they may exhibit invasive growth and destruction of the skull base.
  • [MeSH-major] Adenoma / etiology. Ear Neoplasms / pathology. Endolymphatic Sac. Spinal Cord Neoplasms / secondary

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  • (PMID = 16122027.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Yates CW, Weinberg M, Packer MJ, Jacob A: Fatal case of tumor-associated hemorrhage in a large vestibular schwannoma. Ann Otol Rhinol Laryngol; 2010 Jun;119(6):402-5
Hazardous Substances Data Bank. WARFARIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fatal case of tumor-associated hemorrhage in a large vestibular schwannoma.
  • Vestibular schwannomas are benign neoplasms that arise from Schwann cells of the eighth cranial nerve.
  • During this procedure, a biopsy specimen was obtained, showing benign vestibular schwannoma.

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  • (PMID = 20583739.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticoagulants; 5Q7ZVV76EI / Warfarin
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43. Unsal Tuna EE, Ozbek C, Arda N, Ilkdogan E, Dere H, Ozdem C: Development of a Hodgkin disease tumor in the neck of a patient who previously had undergone complete excision of a hyaline-vascular Castleman disease neck mass. Ear Nose Throat J; 2010 Apr;89(4):E20-3
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  • [Title] Development of a Hodgkin disease tumor in the neck of a patient who previously had undergone complete excision of a hyaline-vascular Castleman disease neck mass.
  • A benign lymphoproliferative disorder, it may be seen as a self-limited unicentric process or as a fulminant multicentric disease with systemic symptoms.
  • [MeSH-major] Giant Lymph Node Hyperplasia / pathology. Hodgkin Disease / pathology. Lymph Node Excision. Otorhinolaryngologic Neoplasms / pathology

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  • (PMID = 20397132.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Koch M, Dimmler A, Alexiou C: [Recurrent and metastasizing atypical fibroxanthoma]. HNO; 2008 Oct;56(10):1046-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atypical fibroxanthoma is a rare skin tumor that arises particularly on sun-exposed skin.
  • Although it is considered to be a benign tumor, rarely, metastases arise.
  • A complete tumor excision was performed, and the patient declined the recommended postoperative radiotherapy.
  • [MeSH-major] Ear Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Neoplasm Recurrence, Local / surgery. Parotid Neoplasms / secondary. Parotid Neoplasms / surgery

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  • (PMID = 18210006.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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45. Miller JP, Semaan M, Einstein D, Megerian CA, Maciunas RJ: Staged Gamma Knife radiosurgery after tailored surgical resection: a novel treatment paradigm for glomus jugulare tumors. Stereotact Funct Neurosurg; 2009;87(1):31-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECT: Although benign and slow growing, glomus jugulare tumors can be locally aggressive because of their proximity to lower cranial nerves and major vascular structures.
  • We report a novel treatment paradigm of tailored surgical resection followed by staged radiosurgery that allows for tissue diagnosis and immediate improvement of symptoms and tumor control without the morbidity of radical surgical resection.
  • METHODS: Five patients with glomus jugulare tumors and contraindications to extensive surgery each underwent an outpatient otologic procedure to resect the portion of the tumor in the middle ear and mastoid with no attempt to remove tumor in the jugular bulb.
  • Each patient returned 2-5 months later for Gamma Knife radiosurgery to the remainder of the tumor, which consisted of one 15-Gy dose prescribed to the 50% isodose curve.
  • Tumor volume was stable or reduced in all patients at most recent follow-up, and there were no immediate or delayed complications.
  • CONCLUSIONS: Staged outpatient microsurgical and radiosurgical therapy for glomus jugulare tumors in the symptomatic patient is safe and yields favorable results regarding tumor size, tinnitus, hearing and cranial nerve status.
  • [MeSH-major] Ear Neoplasms / surgery. Glomus Jugulare Tumor / surgery. Models, Anatomic. Radiosurgery / methods. Reoperation / methods. Skull Neoplasms / surgery

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  • (PMID = 19174618.001).
  • [ISSN] 1423-0372
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
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46. Kazikdas KC, Onal K, Kuehnel TS, Ozturk T: An intradermal nevus of the external auditory meatus. Eur Arch Otorhinolaryngol; 2006 Mar;263(3):253-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 36-year-old woman presented with progressive hearing loss on the right ear, and otomicroscopic examination revealed the presence of a large, violaceous, dome-shaped, papillomatous lesion originating from the posterior wall of the external canal of the right ear.
  • Upon excisional biopsy, the tumor was diagnosed as an intradermal nevus.
  • Thus, this is a unique case of intradermal nevus obstructing the external ear canal with the patient presenting with progressive hearing loss.
  • The possibility of a benign nevomelanocytic nevus should not be underestimated when evaluating a lesion obstructing the ear canal, and all melanocytic nevi should be excised instead of biopsied to rule out melanoma.
  • [MeSH-major] Ear Canal. Nevus, Intradermal / diagnosis. Skin Neoplasms / diagnosis

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  • [Cites] Acta Otorhinolaryngol Belg. 1998;52(1):29-36 [9581194.001]
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  • (PMID = 16012861.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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47. Murali R, Palfreeman S: Clear cell atypical fibroxanthoma - report of a case with review of the literature. J Cutan Pathol; 2006 May;33(5):343-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 67-year-old man presented with a rapidly growing nodule on the ear, which had appeared over a 2-week period.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Ear / pathology. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission

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  • (PMID = 16640540.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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48. Mahalingam M, Kveaton JF, Bhawan J: Cutaneous neuroendocrine adenoma: an uncommon neoplasm. J Cutan Pathol; 2006 Apr;33(4):315-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous neuroendocrine adenoma: an uncommon neoplasm.
  • BACKGROUND: Cutaneous neuroendocrine neoplasms are typically malignant.
  • Benign cutaneous neuroendocrine tumors are uncommon.
  • RESULTS: Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation.
  • CONCLUSIONS: This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.
  • [MeSH-major] Ear Canal. Neuroendocrine Tumors / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Ear Neoplasms / diagnosis. Ear Neoplasms / surgery. Female. Humans. Immunohistochemistry

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  • (PMID = 16630184.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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49. Barbarino S, McCormick SA, Lauer SA, Milman T: Syringocystadenoma papilliferum of the eyelid. Ophthal Plast Reconstr Surg; 2009 May-Jun;25(3):185-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To describe 6 patients with syringocystadenoma papilliferum of the eyelid and to review the literature regarding this rare eyelid tumor.
  • METHODS: Clinicopathologic series of 6 cases, diagnosed at the New York Eye and Ear Infirmary from 1990 to 2006.
  • None of the lesions was associated with a malignant neoplasm.
  • Although syringocystadenoma papilliferum of the eyelid can be associated with other benign lesions, no malignant transformation or association with malignant neoplasms has been reported.
  • The evidence suggests that this tumor should be managed with conservative complete excision.
  • [MeSH-major] Cystadenoma / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19454927.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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50. Agrawal Y, Clark JH, Limb CJ, Niparko JK, Francis HW: Predictors of vestibular schwannoma growth and clinical implications. Otol Neurotol; 2010 Jul;31(5):807-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We evaluated the extent to which tumor growth influences the management of these benign tumors, and we explored symptom markers present at diagnosis that may be predictive of tumor growth.
  • MAIN OUTCOME MEASURE(S): Tumor growth, defined as a 1 mm/year or greater increase in tumor size.
  • RESULTS: We observed that tumor growth was the most important predictor of a change in treatment strategy from serial observation to microsurgical or radiosurgical treatment.
  • We further noted in multivariate analyses that larger tumor size at diagnosis was associated with higher odds of tumor growth, such that each 1-mm increment in tumor size at presentation increased the odds of growth by 20%.
  • We also found that the symptom marker of tinnitus at diagnosis significantly increased the odds of tumor growth nearly 3-fold.
  • CONCLUSION: Tumor growth plays a significant role in guiding the management of vestibular schwannomas.
  • Assessment of tumor size at diagnosis and for the presence of tinnitus may allow for risk stratification of patients with newly diagnosed vestibular schwannomas and for a more rational application of the conservative management approach.
  • [MeSH-major] Ear Neoplasms / pathology. Neuroma, Acoustic / pathology

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  • (PMID = 20502379.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Zhang F, Wang Y, Dai C, Chi F, Zhou L, Chen B, Li H: [Clinical experience in facial nerve tumors: a review of 27 cases]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jan;24(1):4-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To analyze the clinical manifestations and the diagnosis of the facial nerve tumor according to the clinical information, and evaluate the different surgical approaches depending on tumor location.
  • During the course of the disease, 23 patients (85.2%) suffered facial paralysis, both hearing loss and tinnitus affected 11 (40.7%) cases, 5 (18.5%) manifested infra-auricular mass and the others showed some of otalgia or vertigo or ear fullness or facial numbness/twitches.
  • CONCLUSION: Facial nerve tumor is a rare and benign lesion, and has numerous clinical manifestations.
  • [MeSH-major] Cranial Nerve Neoplasms. Facial Nerve Diseases

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  • (PMID = 20235447.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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52. Madani G, Beale T: Tumors of the salivary glands. Semin Ultrasound CT MR; 2006 Dec;27(6):452-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This article reviews the role of imaging in the management of tumors of the salivary glands, discussing tumor localization, extent, and, where possible, characterization.
  • The relative benefits of the different modalities and the typical features of benign and malignant lesions are discussed for each modality.
  • [MeSH-major] Diagnostic Imaging. Salivary Gland Neoplasms / diagnosis

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  • (PMID = 17233228.001).
  • [ISSN] 0887-2171
  • [Journal-full-title] Seminars in ultrasound, CT, and MR
  • [ISO-abbreviation] Semin. Ultrasound CT MR
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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53. Vranic S, Caughron SK, Djuricic S, Bilalovic N, Zaman S, Suljevic I, Lydiatt WM, Emanuel J, Gatalica Z: Hamartomas, teratomas and teratocarcinosarcomas of the head and neck: Report of 3 new cases with clinico-pathologic correlation, cytogenetic analysis, and review of the literature. BMC Ear Nose Throat Disord; 2008;8:8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Germ-cell tumors (GCT) are a histologically and biologically diverse group of neoplasms which primarily occur in the gonads but also develop at different extragonadal sites in the midline of the body.
  • METHODS: We describe here two new cases of multilineage tumors including sinonasal teratocarcinosarcoma [SNTCS], and congenital oronasopharyngeal teratoma (epignathus) and compare their features with those of a new case of a rare salivary gland anlage tumor [SGAT], an entity for which the pathogenesis is unclear (i.e. hamartoma versus neoplasm).
  • Both cytogenetic abnormalities are characteristically present in malignant germ cell tumors providing for the first time evidence that this rare tumor type indeed might represent a variant of a germ cell neoplasm.
  • The SGAT and epignathus carried no such cytogenetic abnormalities, in keeping with their limited and benign biologic potential.
  • Malignant tumors of germ cell origins are more likely to affect adults with insidious symptom development, while benign tumors can nevertheless cause dramatic clinical symptoms which, under certain circumstances, can be fatal.

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  • (PMID = 19025657.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2611960
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54. Yaor MA: The pattern of presentation of salivary gland tumors in Africa: A review of published reports. Ear Nose Throat J; 2010 Feb;89(2):E17-21
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Salivary glands are the site of a wide variety of histopathologic types of benign and malignant tumors.
  • These neoplasms represent a significant health problem in Africa.
  • Also, there may be a female preponderance in Africa, and Warthin tumor is rare.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / epidemiology. Salivary Gland Neoplasms / pathology

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  • (PMID = 20155665.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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55. Taylor J, Stiefel M, Park SY: Schwannoma of the true vocal fold: a rare diagnosis. Ear Nose Throat J; 2006 Jan;85(1):52-3, 59
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Schwannomas of the larynx are rare, benign, slowly growing tumors.
  • When a tumor originates in the larynx, it typically causes hoarseness and a globus sensation.
  • As the tumor expands, it may cause dyspnea, stridor, and possibly asphyxiation as a result of the mass effect.
  • [MeSH-major] Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery. Vocal Cords

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  • (PMID = 16509246.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Kim HJ, McCormick SA, Nath S, Moskowitz B, Milman T: Melanocytic nevi of the tarsal conjunctiva: clinicopathologic case series with review of literature. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):438-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Clinicopathologic series of 4 cases diagnosed at the New York Eye and Ear Infirmary between January 1990 and April 2009.
  • Biopsy, therefore, is prudent as histopathology alone allows documentation of the benign nature of these lesions.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Eyelid Neoplasms / pathology. Nevus, Pigmented / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. Child, Preschool. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 20683369.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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57. Ozcan C, Apa DD, Vayisoglu Y, Görür K: Unilateral parotid gland involvement with synchronous multiple Basal cell adenomas. J Craniofac Surg; 2007 Nov;18(6):1470-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Basal cell adenoma (BCA) is a rare benign epithelial tumor of the salivary gland.
  • The most commonly seen multiple tumor unilaterally or bilaterally is the Warthin's tumor.
  • A 65-year-old woman with a painful, slowly enlarging mass in front of the left ear, which was present for 6 months, was evaluated.
  • More extensive excision of the parotid gland tumor, careful macroscopic perioperative examination of the surgical specimen, and histologic evaluation of all surgical specimens might be necessary for reducing revision operations and surgical complications.
  • [MeSH-major] Adenoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17993904.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Moser A, Hoffmann KM, Walch C, Sovinz P, Lackner H, Schwinger W, Benesch M, Fritz G, Urban C: Intracranial reparative giant cell granuloma secondary to cholesteatoma in a 15-year-old girl. J Pediatr Hematol Oncol; 2008 Dec;30(12):935-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 15-year-old girl presented with pain in the right ear and acute onset of total peripheral facial nerve palsy.
  • A first biopsy led to the diagnosis of intracranial giant cell reparative granuloma (GCRG), a rare benign tumor of the bone or soft tissue that can show expansive growth.
  • Total surgical excision revealed a cholesteatoma central to the GCRG originating from the right middle ear and mastoid.
  • [MeSH-major] Bone Diseases / etiology. Cholesteatoma, Middle Ear / complications. Granuloma, Giant Cell / etiology. Temporal Bone

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  • (PMID = 19131785.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 144O8QL0L1 / Diclofenac
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59. Amin A, Monabati A, Kumar PV, Hashemi SB: Nasal glioma (neuroglial heterotopia) mimicking an astrocytoma: case report. Ear Nose Throat J; 2005 Oct;84(10):657-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nasal glioma is a rare benign tumor that usually occurs during infancy.
  • [MeSH-major] Astrocytoma / diagnosis. Glioma / diagnosis. Neuroglia / pathology. Nose Neoplasms / diagnosis

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  • (PMID = 16382748.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Durden FL Jr, Moore CE, Muller S: Verrucous carcinoma of the paranasal sinuses: a case report. Ear Nose Throat J; 2010 Jul;89(7):E21-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor grows locally invasive but is histologically benign and metastasizes rarely.
  • [MeSH-major] Carcinoma, Verrucous / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Biopsy. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiation effects. Nasal Cavity / surgery. Neoplasm Invasiveness. Neoplasm Staging. Orbital Neoplasms / pathology. Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Skull / pathology. Skull / radiation effects. Skull / surgery. Skull Neoplasms / pathology. Skull Neoplasms / radiotherapy. Skull Neoplasms / surgery

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  • (PMID = 20628974.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. De Gabory L, Deminière C, Stoll D: [Immunohistochemistry expression of 3 markers (CEA, UEA-I and Ki-67) in nasal inverted papillomas]. Rev Laryngol Otol Rhinol (Bord); 2008;129(3):159-65
MedlinePlus Health Information. consumer health - Nasal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Expression immunohistochimique de l'ACE, de l'UEA-I et du Ki-67 dans les papillomes inversés naso-sinusiens.
  • OBJECTIVES: Immunohistochemistry evaluation of the expression of degeneration and proliferation markers of the benign form of Schneiderian inverted papillomas in the ORL sphere, in the nondysplastic, dysplastic and degenerated forms.
  • MATERIALS AND METHOD: 44 surgical specimens were analyzed in two groups: A= 33 benign and B= 11 degenerated.
  • A simultaneous bipolar localization belonged to the two groups (nasal, benign and otologic malignant).
  • But, no difference existed between groups A and B, the various sub-groups and the benign specific localizations.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Ki-67 Antigen / analysis. Nose Neoplasms / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology. Plant Lectins / analysis. Sphenoid Sinus / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Child. Diagnosis, Differential. Ear Neoplasms / pathology. Ear Neoplasms / surgery. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nasal Mucosa / pathology. Nasal Polyps / pathology. Nasal Polyps / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Prognosis. Reference Values

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  • (PMID = 19694158.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Plant Lectins; 0 / Ulex europaeus lectins
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62. de Ru JA, van Leeuwen MS, van Benthem PP, Velthuis BK, Sie-Go DM, Hordijk GJ: Do magnetic resonance imaging and ultrasound add anything to the preoperative workup of parotid gland tumors? J Oral Maxillofac Surg; 2007 May;65(5):945-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: Prospectively, 99 patients with 77 benign and 22 malignant lesions were included; 82 underwent parotidectomy.
  • On PE, the location of the tumor was predicted.
  • Furthermore, the location of the tumor in relation to the facial nerve was predicted.
  • Cytology correctly predicted the benign or malignant nature of the tumor in all cases.
  • CONCLUSION: FNAC is the only accurate investigation for classifying a parotid gland tumor as benign or malignant.
  • Palpation and MRI are superior to US in predicting tumor location.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Biopsy, Fine-Needle / methods. Lymphoma, B-Cell, Marginal Zone / pathology. Parotid Diseases / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Facial Nerve / anatomy & histology. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neoplasm Staging / methods. Parotid Gland / anatomy & histology. Parotid Gland / innervation. Physical Examination. Reference Standards. Single-Blind Method

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  • (PMID = 17448846.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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63. Newton JR, Ruckley RW, Earl UM: Laryngeal neurilemmoma: a case report. Ear Nose Throat J; 2006 Jul;85(7):448-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Published reports of benign nerve sheath tumors of the larynx are extremely rare.
  • We discuss the diagnosis and management of this rare tumor.
  • [MeSH-major] Laryngeal Muscles / pathology. Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery

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  • (PMID = 16909818.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Peterson NR, Summerlin DJ, Cordes SR: Multiple phosphaturic mesenchymal tumors associated with oncogenic osteomalacia: case report and review of the literature. Ear Nose Throat J; 2010 Jun;89(6):E11-5
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Oncogenic osteomalacia is a rare paraneoplastic syndrome that occurs secondary to tumor development in a variety of locations.
  • The most common causal tumor is phosphaturic mesenchymal tumor (PMT), a histologically benign lesion.
  • Despite resection of both tumors, the patient's signs and symptoms did not resolve, suggesting either incomplete tumor removal or the presence of another undetected tumor.
  • [MeSH-major] Bone Neoplasms / etiology. Hypophosphatemia, Familial / pathology. Mesenchymoma / etiology. Osteomalacia / complications. Tibia / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Neoplasms, Connective and Soft Tissue / pathology

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  • (PMID = 20556724.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 36
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65. Cohen AB, Lessell S: Angiogenesis and pituitary tumors. Semin Ophthalmol; 2009 May-Jun;24(3):185-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They are typically slow-growing and histologically benign tumors, but can become clinically destructive, invade adjacent structures, and recur after treatment.
  • [MeSH-major] Neovascularization, Pathologic. Pituitary Neoplasms / blood supply
  • [MeSH-minor] Adenoma / blood supply. Adenoma / metabolism. Adenoma / pathology. Animals. Biomarkers, Tumor / biosynthesis. Blood Vessels / pathology. Humans. Neoplasm Invasiveness. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 19437356.001).
  • [ISSN] 1744-5205
  • [Journal-full-title] Seminars in ophthalmology
  • [ISO-abbreviation] Semin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor A
  • [Number-of-references] 22
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66. Koutsimpelas D, Stripf T, Heinrich UR, Mann WJ, Brieger J: Expression of vascular endothelial growth factor and basic fibroblast growth factor in sporadic vestibular schwannomas correlates to growth characteristics. Otol Neurotol; 2007 Dec;28(8):1094-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Vestibular schwannoma is a benign, slow-growing neoplasm that accounts for 6% of all intracranial tumors.
  • The mRNA expression and the protein expression of both growth factors correlated positive to tumor volume, to tumor growth index, and to MVD.
  • CONCLUSION: The bFGF and VEGF mRNA expression and the bFGF and VEGF protein expression in sporadic VS correlates to the tumour volume, to the tumor growth index, and to the MVD.
  • [MeSH-major] Ear Neoplasms / metabolism. Ear Neoplasms / pathology. Fibroblast Growth Factor 2 / biosynthesis. Neuroma, Acoustic / metabolism. Neuroma, Acoustic / pathology. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 17721409.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / RNA, Messenger; 0 / Vascular Endothelial Growth Factor A; 103107-01-3 / Fibroblast Growth Factor 2
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67. Boulos PR, Knoepp SM, Rubin PA: Green bone. Arch Ophthalmol; 2007 Mar;125(3):380-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To describe the unusual finding of yellow-green-colored bone during routine orbital surgery, to detail its investigation, and to demonstrate its benign nature.
  • RESULTS: Yellow-green bone was encountered in 3 patients during orbital tumor excision or orbital fracture repair procedures.
  • In all cases, absence of neoplasia was demonstrated histologically.
  • [MeSH-minor] Adult. Color. Humans. Male. Microscopy, Fluorescence. Microscopy, Ultraviolet. Middle Aged. Orbital Fractures / surgery. Orbital Neoplasms / radiography. Orbital Neoplasms / surgery. Spectrophotometry, Ultraviolet. Tomography, X-Ray Computed

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  • (PMID = 17353410.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protein Synthesis Inhibitors; F8VB5M810T / Tetracycline
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68. Park YH, Kim SW, Cho SH, Choi YW: Nasopharyngeal glioma causing respiratory distress in a neonate: transoral endoscopic excision. Ear Nose Throat J; 2010 May;89(5):E11-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nasal gliomas are rare, benign, congenital midline tumors made up of heterotopic neuroglial tissue.
  • Preoperative diagnostic imaging is essential to delineate the exact location, limits, and extensions of the tumor and thus to determine the appropriate surgical approach.
  • [MeSH-major] Endoscopy / methods. Glioma / complications. Glioma / surgery. Nasopharyngeal Neoplasms / complications. Nasopharyngeal Neoplasms / surgery. Respiratory Distress Syndrome, Newborn / etiology

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  • (PMID = 20461669.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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69. Persaud R, Tudge S, Amonoo-Kuofi K, Beale T, O'Flynn P: Parapharyngeal granular cell tumour: a unique surgical challenge. J Laryngol Otol; 2005 Jan;119(1):68-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is typically benign but up to seven per cent may be malignant.
  • The authors report a case of a 49-year-old African woman with an oro-naso-parapharyngeal granular cell neoplasm causing mild dysphagia.
  • [MeSH-major] Granular Cell Tumor / surgery. Pharyngeal Neoplasms / surgery

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  • (PMID = 15807973.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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70. Ekşi E, Oztop I: Nerve sheath myxoma of the upper lip: a case report. Kulak Burun Bogaz Ihtis Derg; 2010 Nov-Dec;20(6):318-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nerve sheath myxoma is a benign tumor that rarely occurs in the lip area.
  • [MeSH-major] Lip Neoplasms / surgery. Neurothekeoma / surgery
  • [MeSH-minor] Adult. Cell Division. Female. Humans. Neoplasm Recurrence, Local / prevention & control. S100 Proteins / analysis. Treatment Outcome

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  • (PMID = 20961288.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / S100 Proteins
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71. Roberts DS, Faquin WC, Deschler DG: Giant cell tumors of the temporal bone and infratemporal fossa: a case report and review of the literature. Laryngoscope; 2010;120 Suppl 4:S180
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: To report a giant cell tumor (GCT) of temporal bone and infratemporal fossa and to review the literature pertinent to the care of such patients.
  • RESULTS: Six case reports over 23 years illustrate that these benign locally destructive lesions may originate in the temporal bone with extension into the infratemporal fossa.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Temporal Bone / pathology

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  • (PMID = 21225778.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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72. Hirshoren N, Weinberger JM, Neuman T, Ilan O, Ben-Yaakov A: Recurrent vascular leiomyoma of the larynx: clinical and histopathologic characteristics and treatment. Ear Nose Throat J; 2010 Aug;89(8):382-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Laryngeal vascular leiomyomas are uncommon benign tumors that seldom recur following complete excision.
  • The choice of excision procedure-via direct laryngoscopy or an open approach-is dictated by tumor size, the expected amount of blood loss, and any comorbidities the patient may have.
  • [MeSH-major] Angiomyoma / surgery. Laryngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Adenoma / surgery. Female. Humans. Laryngoscopy. Larynx / pathology. Laser Therapy. Magnetic Resonance Imaging. Medical Records. Middle Aged. Neoplasms, Multiple Primary / surgery. Parathyroid Neoplasms / surgery. Reoperation. Respiration Disorders / etiology

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  • (PMID = 20737377.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Ghanooni R, Decaestecker C, Simon P, Gabius HJ, Hassid S, Choufani G: Characterization of patterns of expression of protein kinase C-alpha, -delta, -eta, -gamma and -zeta and their correlations to p53, galectin-3, the retinoic acid receptor-beta and the macrophage migration inhibitory factor (MIF) in human cholesteatomas. Hear Res; 2006 Apr;214(1-2):7-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cholesteatoma is a benign disease characterized by the presence of an unrestrained growth and the accumulation of keratin in the middle ear cavity.
  • [MeSH-major] Cholesteatoma, Middle Ear / enzymology. Galectin 3 / analysis. Macrophage Migration-Inhibitory Factors / analysis. Protein Kinase C / analysis. Retinoid X Receptor beta / analysis. Tumor Suppressor Protein p53 / analysis

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  • (PMID = 16513304.001).
  • [ISSN] 0378-5955
  • [Journal-full-title] Hearing research
  • [ISO-abbreviation] Hear. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Galectin 3; 0 / Macrophage Migration-Inhibitory Factors; 0 / Retinoid X Receptor beta; 0 / Tumor Suppressor Protein p53; EC 2.7.11.13 / Protein Kinase C
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74. Pant I, Joshi SC, Kaur G, Kumar G: Pilomatricoma as a diagnostic pitfall in clinical practice: report of two cases and review of literature. Indian J Dermatol; 2010 Oct;55(4):390-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pilomatricoma (PMC) is a relatively uncommon benign skin neoplasm arising from the skin adnexa.
  • Since the first description of PMC in 1880, there has been a gradual increase in understanding of the morphologic features and clinical presentation of this tumor.
  • In case 2, a nine-year-old girl presented with a left ear lobe mass.

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  • [Cites] Int J Pediatr Otorhinolaryngol. 2001 Feb;57(2):123-8 [11165649.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2001 Feb;127(2):218, 220 [11177046.001]
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  • (PMID = 21430899.001).
  • [ISSN] 1998-3611
  • [Journal-full-title] Indian journal of dermatology
  • [ISO-abbreviation] Indian J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3051306
  • [Keywords] NOTNLM ; Pilomatricoma / dermatopathology / skin nodules
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75. Ibekwe TS, Kokong DD, Ngwu BA, Akinyemi OA, Nwaorgu OG, Akang EE: Nasal septal teratoma in a child. World J Surg Oncol; 2007;5:58
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Teratoma is a rare developmental neoplasm that arises from totipotential tumor stem cells.
  • CONCLUSION: The prognosis for benign teratoma of the nasal septum is good following total surgical excision.
  • [MeSH-major] Nasal Septum. Nose Neoplasms / pathology. Teratoma / pathology

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  • [Cites] Ear Nose Throat J. 2000 Aug;79(8):620-3 [10969472.001]
  • [Cites] East Afr Med J. 2002 Feb;79(2):106-7 [12380890.001]
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  • (PMID = 17540035.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1891297
  • [General-notes] NLM/ Original DateCompleted: 20070730
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76. Sattar HA, Yang DL, Husain AN, Redleaf MI, Dayal VS: Multiple paragangliomata of the lungs and temporal bone. Ear Nose Throat J; 2008 Nov;87(11):E4-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the case of a 71-year-old woman with multiple benign lung paragangliomata and a benign glomus jugulare paraganglioma in one temporal bone that mimicked a malignancy.
  • A finding of multiple lung paragangliomata should raise the suspicion of a multicentric rather than malignant tumor.
  • [MeSH-major] Lung Neoplasms / secondary. Paraganglioma, Extra-Adrenal / pathology. Skull Neoplasms / secondary. Temporal Bone / pathology

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  • (PMID = 19006054.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Hox V, Vander Poorten V, Delaere PR, Hermans R, Debiec-Rychter M, Sciot R: Extramammary myofibroblastoma in the head and neck region. Head Neck; 2009 Sep;31(9):1240-4
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  • BACKGROUND: Mammary myofibroblastoma is a benign mesenchymal tumor of the breast.
  • CONCLUSION: We describe this case because of the unusual location of this rare tumor.
  • [MeSH-major] Head and Neck Neoplasms. Neoplasms, Muscle Tissue

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  • (PMID = 19132718.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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78. Yaşar H, Ozkul H, Verim A, Ilhan E, Kökten N, Dereci G: [An evaluation of parotid gland masses]. Kulak Burun Bogaz Ihtis Derg; 2007;17(2):70-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathological diagnoses were benign in 33 patients (66%), malignant in nine patients (18%), and tumor-like pathologies in eight patients (16%), the most common being pleomorphic adenoma (n=28, 56%), Warthin's tumor (n=4, 8%), and squamous cell carcinoma (n=4, 8%).
  • [MeSH-major] Neoplasm Recurrence, Local / epidemiology. Parotid Diseases / epidemiology
  • [MeSH-minor] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Adolescent. Adult. Aged. Carcinoma, Squamous Cell / epidemiology. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Parotid Neoplasms / diagnosis. Parotid Neoplasms / epidemiology. Parotid Neoplasms / etiology. Parotid Neoplasms / pathology. Parotid Neoplasms / therapy. Retrospective Studies. Turkey / epidemiology

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  • (PMID = 17527056.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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79. Fussell JN, Cooke ER, Florentino F, Sheehan DJ: Atypical fibroxanthoma with keloidal collagen. Am J Dermatopathol; 2010 Oct;32(7):713-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathology of these neoplasms reveals atypical cells, which often demonstrate positive staining for immunohistochemical markers such as vimentin and CD10.
  • [MeSH-major] Collagen Type I / biosynthesis. Histiocytoma, Benign Fibrous / pathology. Procollagen / biosynthesis. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diabetes Mellitus. Ear / pathology. Humans. Hypertension / complications. Immunohistochemistry. Kidney Failure, Chronic / complications. Male. Middle Aged. Neprilysin / biosynthesis. Renal Dialysis

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  • (PMID = 20700041.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Procollagen; EC 3.4.24.11 / Neprilysin
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80. Doğan S, Can IH, Unlü I, Süngü N, Gönültaş MA, Samim EE: Sialolipoma of the parotid gland. J Craniofac Surg; 2009 May;20(3):847-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The clinical impression was that of a benign salivary gland tumor.
  • The tumor was situated in the superficial lobe of the gland, and a superficial parotidectomy was performed, with preservation of the facial nerve.
  • Preoperative diagnosis is generally difficult, and computed tomographic scanning is useful in defining these benign parotid gland masses.
  • [MeSH-major] Lipoma / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 19390452.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Ramina R, Maniglia JJ, Fernandes YB, Paschoal JR, Pfeilsticker LN, Coelho Neto M: Tumors of the jugular foramen: diagnosis and management. Neurosurgery; 2005 Jul;57(1 Suppl):59-68; discussion 59-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The tumors were approached by a multidisciplinary team composed of neurosurgeons, ear, nose, and throat surgeons, and neuroradiologists.
  • Complete excision was possible in 89% of benign tumors and 80% of paragangliomas.
  • CONCLUSION: Radical removal of benign jugular foramen tumors is the treatment of choice and may be curative.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / surgery. Embolization, Therapeutic / methods. Glomus Jugulare Tumor / diagnosis. Glomus Jugulare Tumor / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Combined Modality Therapy. Female. Glomus Jugulare / pathology. Glomus Jugulare / surgery. Humans. Male. Middle Aged. Retrospective Studies. Skull Base Neoplasms. Treatment Outcome

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  • (PMID = 15987570.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Jakobiec FA, Nguyen J, Bhat P, Fay A: Recurrent blue nevus of the corneoscleral limbus. Cornea; 2010 Aug;29(8):947-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Ki-67 proliferation index was very low (0.05%), supporting a benign diagnosis.
  • CONCLUSIONS: Careful histopathological and immunohistochemical evaluation of recurrent, incompletely excised, blue nevi can determine if they remain benign.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Neoplasm Recurrence, Local. Nevus, Blue / surgery. Scleral Diseases / surgery
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Cryotherapy. Female. Humans. Sclerostomy

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  • (PMID = 20508501.001).
  • [ISSN] 1536-4798
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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83. Korcum AF, Ağirdir BV, Aksu G, Güney K, Dinç O: [Treatment modalities of nasopharyngeal angiofibroma]. Kulak Burun Bogaz Ihtis Derg; 2008 Jul-Aug;18(4):263-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nasopharyngeal angiofibroma is a rare, benign vascular tumor originating from the sphenopalatine foramen.
  • Due to its propensity to locally destructive growth, the tumor may lead to fatal epistaxis, intracranial extension, and life-threatening complications such as intraoperative hemorrhage.
  • [MeSH-major] Angiofibroma / radiotherapy. Angiofibroma / surgery. Nasopharyngeal Neoplasms / radiotherapy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19052499.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 39
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84. Kitahara T, Kubo T, Doi K, Mishiro Y, Kondoh K, Horii A, Okumura S, Miyahara H: [Delayed facial nerve palsy after otologic surgery]. Nihon Jibiinkoka Gakkai Kaiho; 2006 Jul;109(7):600-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Furthermore, DFP was always observed ipsilaterally to the operated ear after otologic surgeries and was never seen after benign parotid tumor surgery or total laryngectomy.

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  • (PMID = 16910581.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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85. Skrivan J, Zvĕrina E, Kluh J, Chovanec M, Pádr R: Our experience with surgical treatment of tympanojugular pragangliomas. Prague Med Rep; 2010;111(1):25-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tympanojugular paragangliomas are benign and slow growing lesions of the lateral skull base.
  • According to the benign character of the tumour, radicality is not always the highest goal, since a radical removal may be compromised by a high postoperative morbidity.
  • [MeSH-major] Ear Neoplasms / surgery. Glomus Jugulare Tumor / surgery. Paraganglioma, Extra-Adrenal / surgery

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  • (PMID = 20359435.001).
  • [ISSN] 1214-6994
  • [Journal-full-title] Prague medical report
  • [ISO-abbreviation] Prague Med Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Czech Republic
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86. Dharia A, Karmody CS, Rebeiz EE: Schwannoma of the nasal cavity. Ear Nose Throat J; 2007 Apr;86(4):230-1, 243
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Schwannomas are benign peripheral nerve sheath tumors that occur throughout the body.
  • [MeSH-major] Nasal Cavity / surgery. Neurilemmoma / surgery. Nose Neoplasms / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Nasal Obstruction / etiology. Nasal Obstruction / surgery. Nasal Septum / pathology. Nasal Septum / surgery. Otoscopy. S100 Proteins / analysis. Tomography, X-Ray Computed

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  • (PMID = 17500396.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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87. Lenarz M, Durisin M, Kamenetzki P, Becker H, Kreipe HH, Lenarz T: Cavernous hemangioma of the internal auditory canal. Eur Arch Otorhinolaryngol; 2007 May;264(5):569-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The presence of a small contrast-enhancing tumor in the internal auditory canal accompanied by severe sensorineural hearing loss and facial nerve palsy, should raise the suspicion of a hemangioma.
  • Early recognition and surgical intervention in these benign tumors may improve the chance of preserving the functional integrity of the facial nerve and provides better results after nerve reconstruction.
  • [MeSH-major] Ear, Inner / pathology. Facial Nerve / pathology. Hemangioma, Cavernous / pathology. Peripheral Nervous System Neoplasms / pathology. Vestibulocochlear Nerve / pathology

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  • [Cites] Ann Otol Rhinol Laryngol. 2004 Jun;113(6):431-7 [15224824.001]
  • [Cites] Am J Otol. 1992 May;13(3):223-32 [1609850.001]
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  • (PMID = 17235534.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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88. Kwon H, Kim HY, Jung SN, Sohn WI, Yoo G: Extraskeletal chondroma in the auricle. J Craniofac Surg; 2010 Nov;21(6):1990-1
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for extraskeletal chondroma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extraskeletal chondroma is a rare benign tumor that develops in soft tissues, and histologically, it is a lobulated nodule surrounded by a fibrous capsule, and the inside consists of mature cartilage cells and diffuse hyalinized matrix.
  • [MeSH-major] Chondroma / diagnosis. Ear Auricle / pathology. Ear Neoplasms / diagnosis

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  • (PMID = 21119479.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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89. Butman JA, Linehan WM, Lonser RR: Neurologic manifestations of von Hippel-Lindau disease. JAMA; 2008 Sep 17;300(11):1334-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • von Hippel-Lindau disease (VHL) is an autosomal-dominant neoplasia syndrome that is the result of a germline mutation of the VHL tumor suppressor gene on the short arm of chromosome 3.
  • Central nervous system lesions include hemangioblastomas (the most common tumor in VHL) and endolymphatic sac tumors (ELSTs).
  • Despite their benign pathology, hemangioblastomas and ELSTs are a frequent cause of morbidity and mortality in patients with VHL.

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  • (PMID = 18799446.001).
  • [ISSN] 1538-3598
  • [Journal-full-title] JAMA
  • [ISO-abbreviation] JAMA
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / BC / Z01 BC011038-01; United States / NCI NIH HHS / BC / Z01 BC011089-01; United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Clinical Conference; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Other-IDs] NLM/ NIHMS410216; NLM/ PMC3487164
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90. Witt RL: Minimally invasive surgery for parotid pleomorphic adenoma. Ear Nose Throat J; 2005 May;84(5):308, 310-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Compared with total parotidectomy and complete superficial parotidectomy for the removal of a parotid pleomorphic adenoma, partial superficial parotidectomy with dissection and preservation of the facial nerve--defined as the excision of a tumor with a 2-cm margin of normal parotid parenchyma except at the point where the tumor abuts the facial nerve--is associated with a lower incidence of transient facial nerve dysfunction, facial contour disfigurement, and subsequent Frey's syndrome.
  • The author hypothesized that the use of this procedure to remove a benign pleomorphic adenoma might result in even less morbidity (transient or permanent facial nerve dysfunction, facial contour disfigurement, Frey's syndrome, and hypoesthesia) without increasing the risk of recurrence if only a 1-cm margin of normal parotid parenchyma was removed and if the posterior branches of the great auricular nerve were preserved To test this hypothesis, the author conducted a retrospective study of 30 patients--15 who had undergone the standard partial procedure (2-cm margin with great auricular nerve sacrifice) and 15 who had undergone the modified version (1-cm margin with great auricular nerve preservation).
  • Although a 1-cm area of normal parotid parenchyma around a benign pleomorphic adenoma was a safe margin, it was no better than a 2-cm margin in terms ofmorbidity and recurrence.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Parotid Neoplasms / surgery

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  • (PMID = 15971755.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Shin JU, Lee KY, Roh MR: A case of a cutaneous angiomyolipoma. Ann Dermatol; 2009 May;21(2):217-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A cutaneous angiomyolipoma, which is also known as a cutaneous angiolipoleiomyoma, is a rare benign mesenchymal tumor.
  • We describe a case of an angiomyolipoma presenting on the right ear helix of a 26-year-old female.

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  • (PMID = 20523792.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861200
  • [Keywords] NOTNLM ; Angiolipoleiomyoma / Angiomyolipoma
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92. Xiao H, Gong S, Nie X, Guo C, Zhong G: [Ossifying fibroma of the temporal bone]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Oct;20(19):868-70
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient was a 8-year-old boy with a one year history of left ear discomfort, suppurative otorrhea and progressive hearing loss.
  • Physical examination of the ear revealed a stenosis of left external auditory canal (EAC), and an obvious expansion at mastoid region.
  • Audiometry showed no hearing of the left ear.
  • Frozen section evaluation during operation was not definitive but suggested benign nature in histology.
  • The tumor was fully resected.
  • One-year follow-up showed the sealed EAC was satisfactory with complete interior and no tumor recurred.
  • CONCLUSION: Ossifying fibroma of the temporal bone is a rare entity, which is a benign neoplasm but may show an aggressive behavior by compression and encroachment upon adjacent structures.
  • [MeSH-major] Bone Neoplasms. Fibroma, Ossifying. Temporal Bone / pathology

  • MedlinePlus Health Information. consumer health - Bone Cancer.
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  • (PMID = 17168109.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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93. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery]. Ugeskr Laeger; 2005 Aug 22;167(34):3167-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood.
  • The embolization, which was carried out in the radiotherapy department, was done with polyvinyl alcohol particles in the vessels that supply the tumor.
  • The operation was then performed in the ear, nose and throat department of OUH.
  • The tumor was removed endoscopically in all cases in which it was possible.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / therapy

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117915.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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94. Madhumita K, Nambiar A, Prathapan P: Solitary neurofibroma of the palatine tonsil: a case report. Ear Nose Throat J; 2007 Dec;86(12):756-8
Genetic Alliance. consumer health - Neurofibroma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present a rare case of a benign tumor of the tonsil in a 49-year-old woman.
  • The tumor was excised in its entirety, and the patient's postoperative course was uneventful.
  • [MeSH-major] Neurofibroma / pathology. Tonsillar Neoplasms / pathology

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  • (PMID = 18217382.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Kiss S, Gragoudas ES, Dryja TP, Jakobiec FA: Response of choroidal leiomyoma to treatment with proton beam radiation. Retin Cases Brief Rep; 2010;4(2):168-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Uveal leiomyoma is a rare, benign smooth muscle neoplasm usually diagnosed only after local resection or enucleation.
  • The neoplasm was treated with a total of 70 cobalt gray equivalents of external proton beam radiation in 5 fractions over 7 days.
  • Biannual follow-up examinations over 3 years showed a funduscopically and ultrasonographically regressing tumor.
  • Microscopic and immunohistochemical examination of the mass revealed a choroidal neoplasm expressing smooth muscle antigens consistent with a uveal leiomyoma.

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  • (PMID = 25390394.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Huang Q, Wu H, Xiang M, Wang Z, Wang Z: [Cavernous hemangioma in internal auditory canal: case report and review of the literature]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Oct;20(19):873-5
Genetic Alliance. consumer health - Hemangioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULT: The tumor was totally removed by translabyrinthine approach without any complication, such as facial paralysis or cerebrospinal fluid otorrhea.
  • It is a rare occupying lesion in IAC of benign nature.
  • [MeSH-major] Ear Canal / pathology. Ear Neoplasms. Ear, Inner / pathology. Hemangioma, Cavernous

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  • (PMID = 17168111.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
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97. Ethmoidal osteoid osteoma with orbital and intracranial extension - a case report. BMC Ear Nose Throat Disord; 2005 Mar 11;5:2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton.
  • Radical excision of the tumor could thus be achieved through a craniofacial approach.
  • CONCLUSION: Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures.

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  • (PMID = 15760476.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC555567
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98. Fine HF, Ferrara DC, Ho IV, Takahashi B, Yannuzzi LA: Bilateral choroidal osteomas with polypoidal choroidal vasculopathy. Retin Cases Brief Rep; 2008;2(1):15-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: A choroidal osteoma is a benign osseous tumor typically arising in the juxtapapillary or peripapillary area.
  • To our knowledge, this variant form of vasogenesis has not previously been described in association with this tumor.

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  • (PMID = 25389606.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Jana AK, Jaswal A, Sikder B, Jana U, Nandi TK: Surgical management of parapharyngeal tumors - our experience. Indian J Otolaryngol Head Neck Surg; 2008 Dec;60(4):345-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fifteen cases of parapharyngeal tumors treated surgically in ENT department of Calcutta National Medical College in last 2 years were included, 80% cases were of benign tumors, most common being schwannomas.
  • The study gives an overview regarding the surgical approach, based upon the extent and histology of the tumor and transcervical approach was found to be most efficient for all practical purpose.

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  • (PMID = 23120578.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3476807
  • [Keywords] NOTNLM ; Parapharyngeal tumors / Surgical management
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100. Abram S, Rosenblatt P, Holcomb S: Stereotactic radiation techniques in the treatment of acoustic schwannomas. Otolaryngol Clin North Am; 2007 Jun;40(3):571-88, ix
MedlinePlus Health Information. consumer health - Acoustic Neuroma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The goals of the treatment of acoustic schwannomas are prohibiting tumor growth and alleviation of symptoms caused by damage to local structures.
  • These symptoms-tinnitus, ataxia, and hearing loss--secondary to eighth nerve dysfunction, as well as symptoms arising from damage to adjacent structures such as the facial nerve, trigeminal nerve, or pons, can be caused by tumor growth or treatment.
  • Determination of optimal therapy must also take into account an understanding of the natural history of the disease, because acoustic schwannomas are slow-growing benign tumors that when left untreated, usually enlarge over time and cause problems.
  • [MeSH-major] Ear Neoplasms / pathology. Ear Neoplasms / radiotherapy. Neuroma, Acoustic / pathology. Neuroma, Acoustic / radiotherapy. Radiosurgery / instrumentation. Stereotaxic Techniques
  • [MeSH-minor] Algorithms. Dose Fractionation. Follow-Up Studies. Humans. Hydrocephalus / epidemiology. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neurofibromatosis 2 / epidemiology. Tinnitus / epidemiology. Vertigo / epidemiology

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  • (PMID = 17544696.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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