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1. Yaor MA: The pattern of presentation of salivary gland tumors in Africa: A review of published reports. Ear Nose Throat J; 2010 Feb;89(2):E17-21
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  • Salivary glands are the site of a wide variety of histopathologic types of benign and malignant tumors.
  • These neoplasms represent a significant health problem in Africa.
  • Also, there may be a female preponderance in Africa, and Warthin tumor is rare.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / epidemiology. Salivary Gland Neoplasms / pathology

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  • (PMID = 20155665.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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2. Orita Y, Hamaya K, Miki K, Sugaya A, Hirai M, Nakai K, Nose S, Yoshino T: Satellite tumors surrounding primary pleomorphic adenomas of the parotid gland. Eur Arch Otorhinolaryngol; 2010 May;267(5):801-6
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  • The occasional local recurrence of benign pleomorphic adenoma (PA) has generally been attributed to the vulnerability of the tumor capsule.
  • In most cases, such satellite tumors will arise from capsular perforation of the primary tumor cells.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasms, Second Primary / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Genes, p53 / genetics. Humans. Immunohistochemistry. Infant. Infant, Newborn. Ki-67 Antigen / genetics. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Point Mutation / genetics. Preoperative Care

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  • (PMID = 19898859.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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3. Ren WH, Zhi KQ, Gao L, Xu Y, Li XQ, Shi MJ: [Clinical utilization of veiled incision and sternocleidomastoid flap in parotidectomy of parotid benign tumors]. Shanghai Kou Qiang Yi Xue; 2010 Jun;19(3):232-5
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  • [Title] [Clinical utilization of veiled incision and sternocleidomastoid flap in parotidectomy of parotid benign tumors].
  • There was no significant difference between these two groups in temporary facial paralysis, salivary fistula, tumor recurrence, Frey's syndrome, the feeling of the region around the auricular lobule.
  • [MeSH-minor] Ear Auricle. Face. Humans. Neoplasms. Parotid Neoplasms. Postoperative Complications. Surgical Flaps

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  • (PMID = 20635029.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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4. Pant I, Joshi SC, Kaur G, Kumar G: Pilomatricoma as a diagnostic pitfall in clinical practice: report of two cases and review of literature. Indian J Dermatol; 2010 Oct;55(4):390-2
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  • Pilomatricoma (PMC) is a relatively uncommon benign skin neoplasm arising from the skin adnexa.
  • Since the first description of PMC in 1880, there has been a gradual increase in understanding of the morphologic features and clinical presentation of this tumor.
  • In case 2, a nine-year-old girl presented with a left ear lobe mass.

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  • (PMID = 21430899.001).
  • [ISSN] 1998-3611
  • [Journal-full-title] Indian journal of dermatology
  • [ISO-abbreviation] Indian J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3051306
  • [Keywords] NOTNLM ; Pilomatricoma / dermatopathology / skin nodules
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5. Sciarretta V, Pasquini E, Frank G, Modugno GC, Cantaroni C, Mazzatenta D, Farneti G: Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases. Am J Rhinol; 2006 Jan-Feb;20(1):64-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases.
  • BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma.
  • METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively.
  • The endoscopic approach was simple in 28 cases and associated with an external approach in 5 cases (because of an intracranial extension of the tumor in four patients and its location at the level of the anterior wall of the frontal sinus in the last case).
  • CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.
  • [MeSH-major] Endoscopy / methods. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 16539297.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Onal C, Yuksel O, Topkan E, Pehlivan B: Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report. Cases J; 2009;2:8402
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  • [Title] Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report.
  • INTRODUCTION: Glomus tumors are benign, slow growing tumors originating from paraganglionic tissue, mostly located at the carotid bifurcation, jugular foramen, cervical portion vagus nerve, and middle ear cavity.
  • CASE PRESENTATION: We present a 53-year-old female patient with a glomus tumor treated with positron emission tomography computed tomography planning and 3D conformal radiotherapy, and the patient has remained free of disease progression 2 years after.
  • CONCLUSION: It is suggested that radiotherapy is a good treatment modality in patients with glomus tumor, and metabolic imaging and treatment planning with positron emission tomography computed tomography is superior to other imaging modalities.

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  • (PMID = 19918426.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769436
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7. Taylor J, Stiefel M, Park SY: Schwannoma of the true vocal fold: a rare diagnosis. Ear Nose Throat J; 2006 Jan;85(1):52-3, 59
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  • Schwannomas of the larynx are rare, benign, slowly growing tumors.
  • When a tumor originates in the larynx, it typically causes hoarseness and a globus sensation.
  • As the tumor expands, it may cause dyspnea, stridor, and possibly asphyxiation as a result of the mass effect.
  • [MeSH-major] Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery. Vocal Cords

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  • (PMID = 16509246.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Strehl MA, Scheich M, Ott I, Müller-Hermelink HK, Hagen R, Völker HU: [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?]. Laryngorhinootologie; 2009 Mar;88(3):186-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?].
  • [Transliterated title] Mittelohradenom/Mittelohrkarzinoid--ein unproblematischer Tumor?
  • OBJECTIVES: Adenomas/carcinoid tumors of the middle ear are very rare tumors of young to middle aged patients.
  • The terms adenoma and carcinoid tumor of the middle ear can be used as synonyms, with the WHO favouring the term middle ear adenoma (MEA).
  • They are classified as benign tumors with only very few reported cases of regional metastasis after years of disease.
  • METHODS AND PATIENTS: This study describes the clinical course and the diagnostic challenges in four cases of this rare tumor entity.
  • In two cases a tumor recurrence was documented with one case recurring six times.
  • CONCLUSION: Adenomas of the middle ear can have a much more complicated clinical course than is suggested by the recent literature.
  • The presented cases in this study and the analysis of previously published cases shows that the typical progression described by the current WHO-classification with unproblematic surgical management of the tumor and an uncomplicated further clinical course does not always correspond to reality.
  • [MeSH-major] Adenoma / diagnosis. Carcinoid Tumor / diagnosis. Ear Neoplasms / diagnosis. Ear, Middle
  • [MeSH-minor] Adult. Cholesteatoma, Middle Ear / diagnosis. Cholesteatoma, Middle Ear / pathology. Cholesteatoma, Middle Ear / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / surgery. Otoscopy. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 19065497.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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9. Okada K, Ito K, Yamasoba T, Ishii M, Iwasaki S, Kaga K: Benign mass lesions deep inside the temporal bone: imaging diagnosis for proper management. Acta Otolaryngol Suppl; 2007 Dec;(559):71-7
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  • [Title] Benign mass lesions deep inside the temporal bone: imaging diagnosis for proper management.
  • CONCLUSION: Among mass lesions inside the temporal bone, benign tumors and cholesteatomas can be differentiated by contrast enhancement in T1-weighted images (T1WI) and by diffusion-weighted images (DWI).
  • RESULTS: One patient had facial schwannoma, two had glomus jugulare tumor, and three had cholesteatoma.
  • MRI study provided us with better clues: contrast enhancement on T1WI was observed only in benign tumors and only cholesteatomas showed high intensity on DWI.
  • [MeSH-major] Cholesteatoma, Middle Ear. Cranial Nerve Neoplasms / diagnosis. Cranial Nerve Neoplasms / surgery. Facial Nerve. Glomus Jugulare Tumor / diagnosis. Granuloma / diagnosis. Granuloma / surgery. Mucocele / diagnosis. Neurilemmoma / diagnosis. Neurilemmoma / surgery. Temporal Bone

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  • (PMID = 18340574.001).
  • [ISSN] 0365-5237
  • [Journal-full-title] Acta oto-laryngologica. Supplementum
  • [ISO-abbreviation] Acta Otolaryngol Suppl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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10. Doğan S, Can IH, Unlü I, Süngü N, Gönültaş MA, Samim EE: Sialolipoma of the parotid gland. J Craniofac Surg; 2009 May;20(3):847-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The clinical impression was that of a benign salivary gland tumor.
  • The tumor was situated in the superficial lobe of the gland, and a superficial parotidectomy was performed, with preservation of the facial nerve.
  • Preoperative diagnosis is generally difficult, and computed tomographic scanning is useful in defining these benign parotid gland masses.
  • [MeSH-major] Lipoma / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 19390452.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Koutsimpelas D, Stripf T, Heinrich UR, Mann WJ, Brieger J: Expression of vascular endothelial growth factor and basic fibroblast growth factor in sporadic vestibular schwannomas correlates to growth characteristics. Otol Neurotol; 2007 Dec;28(8):1094-9
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  • BACKGROUND: Vestibular schwannoma is a benign, slow-growing neoplasm that accounts for 6% of all intracranial tumors.
  • The mRNA expression and the protein expression of both growth factors correlated positive to tumor volume, to tumor growth index, and to MVD.
  • CONCLUSION: The bFGF and VEGF mRNA expression and the bFGF and VEGF protein expression in sporadic VS correlates to the tumour volume, to the tumor growth index, and to the MVD.
  • [MeSH-major] Ear Neoplasms / metabolism. Ear Neoplasms / pathology. Fibroblast Growth Factor 2 / biosynthesis. Neuroma, Acoustic / metabolism. Neuroma, Acoustic / pathology. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 17721409.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / RNA, Messenger; 0 / Vascular Endothelial Growth Factor A; 103107-01-3 / Fibroblast Growth Factor 2
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12. Cohen AB, Lessell S: Angiogenesis and pituitary tumors. Semin Ophthalmol; 2009 May-Jun;24(3):185-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They are typically slow-growing and histologically benign tumors, but can become clinically destructive, invade adjacent structures, and recur after treatment.
  • [MeSH-major] Neovascularization, Pathologic. Pituitary Neoplasms / blood supply
  • [MeSH-minor] Adenoma / blood supply. Adenoma / metabolism. Adenoma / pathology. Animals. Biomarkers, Tumor / biosynthesis. Blood Vessels / pathology. Humans. Neoplasm Invasiveness. Vascular Endothelial Growth Factor A / biosynthesis

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  • (PMID = 19437356.001).
  • [ISSN] 1744-5205
  • [Journal-full-title] Seminars in ophthalmology
  • [ISO-abbreviation] Semin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor A
  • [Number-of-references] 22
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13. de Ru JA, van Leeuwen MS, van Benthem PP, Velthuis BK, Sie-Go DM, Hordijk GJ: Do magnetic resonance imaging and ultrasound add anything to the preoperative workup of parotid gland tumors? J Oral Maxillofac Surg; 2007 May;65(5):945-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: Prospectively, 99 patients with 77 benign and 22 malignant lesions were included; 82 underwent parotidectomy.
  • On PE, the location of the tumor was predicted.
  • Furthermore, the location of the tumor in relation to the facial nerve was predicted.
  • Cytology correctly predicted the benign or malignant nature of the tumor in all cases.
  • CONCLUSION: FNAC is the only accurate investigation for classifying a parotid gland tumor as benign or malignant.
  • Palpation and MRI are superior to US in predicting tumor location.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Biopsy, Fine-Needle / methods. Lymphoma, B-Cell, Marginal Zone / pathology. Parotid Diseases / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Facial Nerve / anatomy & histology. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Neoplasm Staging / methods. Parotid Gland / anatomy & histology. Parotid Gland / innervation. Physical Examination. Reference Standards. Single-Blind Method

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  • (PMID = 17448846.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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14. Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V: Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol; 2008 Mar-Apr;29(2):142-6
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  • [Title] Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review.
  • INTRODUCTION: Primary neoplasms of the external ear canal are rare, and 5% of these tumors are of glandular origin.
  • Ceruminal glands are modified sweat glands of the skin of the external auditory meatus that may give rise to (a) benign tumors such as ceruminous adenoma, pleomorphic adenoma, and syringocystadenoma papilliferum, and (b) malignant tumors such as ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma.
  • An alternative theory holds that pleomorphic adenomas may well arise from ectopic salivary tissue present in the external ear canal.
  • These tumors are very rare and usually have a benign course.
  • In this report, we describe an unusual case of pleomorphic adenoma of the external auditory canal associated with chronic infection of the middle ear.
  • She had been affected with chronic otitis media and aural polyps for the last 13 years, for which she had received medical treatment only.
  • A canal-filling aural polyp was noted on clinical examination.
  • Subsequent biopsy and histologic examination revealed pleomorphic adenoma of the external ear canal, possibly with malignant elements.
  • The patient underwent modified radical mastoidectomy and complete resection of the tumor and the entire skin of the external auditory canal.
  • CONCLUSIONS: Pleomorphic adenoma is an extremely rare tumor arising from the ceruminal glands of the external ear canal.
  • Nonspecific presentation and difficult histologic diagnosis characterize this benign neoplasm.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear, External / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 18314029.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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15. Kuklani RM, Glavin FL, Bhattacharyya I: Malignant cylindroma of the scalp arising in a setting of multiple cylindromatosis: a case report. Head Neck Pathol; 2009 Dec;3(4):315-9
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  • The tumor apparently arose from a cylindroma and had features of spiradenoma.
  • Cylindroma is an uncommon benign tumor, which originates from skin appendages and is most commonly found on the scalp and face with a strong predilection for middle-aged and elderly females.
  • Although cylindromas are usually benign neoplasms, carcinoma arising in such neoplasms is rare with only sporadic reports in literature.
  • The patient's main concern was painful lesions over her right ear that interfered with wearing of her glasses.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Neoplasms, Multiple Primary / pathology. Scalp / pathology. Skin Neoplasms / pathology

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  • [Cites] Br J Dermatol. 2001 Oct;145(4):653-6 [11703297.001]
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  • (PMID = 20596852.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2811564
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16. Korcum AF, Ağirdir BV, Aksu G, Güney K, Dinç O: [Treatment modalities of nasopharyngeal angiofibroma]. Kulak Burun Bogaz Ihtis Derg; 2008 Jul-Aug;18(4):263-7
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  • Nasopharyngeal angiofibroma is a rare, benign vascular tumor originating from the sphenopalatine foramen.
  • Due to its propensity to locally destructive growth, the tumor may lead to fatal epistaxis, intracranial extension, and life-threatening complications such as intraoperative hemorrhage.
  • [MeSH-major] Angiofibroma / radiotherapy. Angiofibroma / surgery. Nasopharyngeal Neoplasms / radiotherapy. Nasopharyngeal Neoplasms / surgery

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  • (PMID = 19052499.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 39
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17. Archibald DJ, Neff BA, Voss SG, Splinter PL, Driscoll CL, Link MJ, Dong H, Kwon ED: B7-H1 expression in vestibular schwannomas. Otol Neurotol; 2010 Aug;31(6):991-7
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  • BACKGROUND: Little is known about how benign human vestibular schwannomas interact with antibody-mediated or cell-mediated immunity.
  • We report on the aberrant expression of a novel T-cell coregulatory molecule, B7 homolog 1 (B7-H1), in vestibular schwannomas and discuss the implications of B7-H1 expression and tumor aggressiveness and a potential regulator of B7-H1 expression.
  • A clinical review of patient presenting symptoms and tumor characteristics was performed.
  • Failure of tumor control with stereotactic radiation (p = 0.029) was significantly greater in the strongly positive B7-H1 tumors.
  • Although clinical trends were seen, greater statistical power is required to evaluate whether B7-H1 expression correlates with more aggressive tumor growth or poorer hearing class.

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  • (PMID = 20601920.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA134345-03; United States / NCI NIH HHS / CA / R01 CA134345; United States / NCI NIH HHS / CA / R01 CA134345-03
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD274; 0 / CD274 protein, human; 0 / RNA, Messenger
  • [Other-IDs] NLM/ NIHMS242934; NLM/ PMC4810681
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18. Zehlicke T, Punke C, Haase K, Boltze C, Pau HW: [Myxoma of the middle ear-a rare cause of facial palsy]. HNO; 2008 Feb;56(2):165-8
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  • [Title] [Myxoma of the middle ear-a rare cause of facial palsy].
  • [Transliterated title] Das Myxom des Mittelohrs als mögliche Ursache einer temporären Fazialisparese.
  • In case of the co-occurrence of facial palsy and inflammation-like symptoms of the same ear, the differential diagnosis is focused on viral (herpes zoster) or bacterial diseases.
  • We report a patient for whom the surgical exploration of the middle ear revealed a benign tumor: a myxoma.
  • These neoplasias are rare tumors in the head and neck region.
  • The typical tumor site is the atrium of heart.
  • In the ear, the tumor grows slowly and remains asymptomatic unless it irritates structures such as the facial nerve or the vestibular organ.
  • Histologically, the tumor presents a "myxoid" matrix that is rich in acid mucopolysaccarides.
  • Using the case presented, we discuss the causality between the tumor and the facial palsy, although during the operation the bony canal of the nerve was found to be intact.
  • In any cases with clinically and radiologically unclear findings of the ear in connection with facial palsy, surgical exposure should be considered.
  • [MeSH-major] Ear Neoplasms / complications. Ear, Middle. Facial Paralysis / etiology. Myxoma / complications

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  • [Cites] HNO. 1969 Apr;17 (4):113-5 [5405595.001]
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  • (PMID = 17115088.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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19. Sanna M, Fois P, Pasanisi E, Russo A, Bacciu A: Middle ear and mastoid glomus tumors (glomus tympanicum): an algorithm for the surgical management. Auris Nasus Larynx; 2010 Dec;37(6):661-8
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  • [Title] Middle ear and mastoid glomus tumors (glomus tympanicum): an algorithm for the surgical management.
  • OBJECTIVE: Glomus tumors are slow-growing benign lesions and represent the most common primary neoplasms of the middle ear.
  • METHODS: Between December 1988 and July 2008, 68 patients with histologically confirmed glomus tympanicum tumor underwent surgical treatment.
  • Nineteen patients with larger Class B tumors underwent a subtotal petrosectomy with blind sac closure of the external auditory canal and middle ear obliteration.
  • Gross total tumor removal was achieved in all 68 cases.
  • CONCLUSION: Surgical excision of glomus tympanicum tumors is a safe procedure, allowing total tumor removal with minimal morbidity, a low recurrence rate, and a low complication rate.
  • [MeSH-major] Algorithms. Ear Neoplasms / surgery. Ear, Middle. Glomus Tympanicum Tumor / surgery. Mastoid. Skull Neoplasms / surgery. Surgical Procedures, Operative
  • [MeSH-minor] Adult. Aged. Audiometry. Female. Follow-Up Studies. Hearing Loss / diagnosis. Hearing Loss / etiology. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Otologic Surgical Procedures. Postoperative Period. Reoperation. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome. Tympanic Membrane Perforation / etiology. Young Adult

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  • [Copyright] Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20400250.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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20. Cheung FM, Lau TW, Cheung LK, Li AS, Chow SK, Lo AW: Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV. Ear Nose Throat J; 2010 Oct;89(10):E5-E12
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  • [Title] Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV.
  • Schneiderian papillomas are uncommon benign tumors of the sinonasal area.
  • For each case, we documented the morphology, immunohistochemical expression of tumor suppressor genes p53 and p16, and any association with human papillomavirus (HPV) infection as detected by either polymerase chain reaction or in situ hybridization techniques.
  • [MeSH-major] Genes, p16 / physiology. Genes, p53 / physiology. Nasal Mucosa. Nose Neoplasms / pathology. Papilloma / pathology

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  • (PMID = 20981655.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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21. Kim BH, Henderson BA: Intraocular choristoma. Semin Ophthalmol; 2005 Oct-Dec;20(4):223-9
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  • Although it is regarded as a benign tumor, it grows progressively and can decrease visual function.

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  • (PMID = 16352493.001).
  • [ISSN] 0882-0538
  • [Journal-full-title] Seminars in ophthalmology
  • [ISO-abbreviation] Semin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 54
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22. Barbarino S, McCormick SA, Lauer SA, Milman T: Syringocystadenoma papilliferum of the eyelid. Ophthal Plast Reconstr Surg; 2009 May-Jun;25(3):185-8
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  • PURPOSE: To describe 6 patients with syringocystadenoma papilliferum of the eyelid and to review the literature regarding this rare eyelid tumor.
  • METHODS: Clinicopathologic series of 6 cases, diagnosed at the New York Eye and Ear Infirmary from 1990 to 2006.
  • None of the lesions was associated with a malignant neoplasm.
  • Although syringocystadenoma papilliferum of the eyelid can be associated with other benign lesions, no malignant transformation or association with malignant neoplasms has been reported.
  • The evidence suggests that this tumor should be managed with conservative complete excision.
  • [MeSH-major] Cystadenoma / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19454927.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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23. Hwang HS, Lee WJ, Lim HK, Chun HK, Ahn GH: Chondrolipoma in the pelvic cavity: a case report. Korean J Radiol; 2008 Nov-Dec;9(6):563-7
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  • A chondrolipoma is an extremely rare form of a benign mesenchymal tumor containing mature cartilage and fatty tissue.
  • [MeSH-major] Chondroma / diagnosis. Lipoma / diagnosis. Mesenchymoma / diagnosis. Pelvic Neoplasms / diagnosis

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  • (PMID = 19039275.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627234
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24. Rydzewski B, Goździcka-Józefiak A, Sokalski J, Matusiak M, Durzyński L: [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms]. Otolaryngol Pol; 2007;61(2):137-41
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  • [Title] [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms].
  • There's a hypothesis, that it plays a significant role in middle ear chronic inflammations and neoplasm's.
  • The examination was carried on a group of 53 patients, 39 of which was suffering from granulation tissue chronic otitis media, 7-cholesteatomatous otitis media, 6--middle ear malignant neoplasm, and 1 middle and/or external ear benign neoplasm.
  • The material was postoperative tissue, like polyps, inflammatory granulation tissue, cholesteatoma masses and malignant neoplasm's tissue.
  • In every case of middle ear malignant neoplasm a presence of high-risk DNA Papilloma types 16 or 18 was confirmed.
  • CONCLUSIONS: The results has been compared with other authors examinations and it is claimed that they confirm the observation, that Human Papilloma Viruses may be a factor, that might play an important role in pathology of chronic otitis media and ear neoplasm's.
  • It is concluded, that differences in percentages of HPV presence in chronic inflammations (70%) and ear neoplasm's may be explained by viral co-infection during bacterial c. o. m.
  • [MeSH-major] Ear / virology. Ear Neoplasms / virology. Papilloma / genetics. Papilloma / virology. Papillomavirus Infections / diagnosis. Tumor Virus Infections / diagnosis. Tumor Virus Infections / virology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Cholesteatoma, Middle Ear / epidemiology. Cholesteatoma, Middle Ear / virology. Female. Humans. Male. Middle Aged. Otitis Media / epidemiology. Otitis Media / virology. Poland / epidemiology. Polymerase Chain Reaction. Prognosis

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  • (PMID = 17668798.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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25. Zhou L, Luo L, Hui X, Chen H, Yu B, Guo G, You C: Primary Rathke's cleft cyst in the cerebellopontine angle associated with apoplexy. Childs Nerv Syst; 2010 Dec;26(12):1813-7
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  • Rathke's cleft cyst (RCC) is a congenital, benign, epithelial tumor and mainly occurs in sellar region and occasionally in suprasellar region; ectopic RCC is exceedingly rare.
  • The patient underwent the total tumor removal via the retrosigmoid approach with a good recovery.

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  • (PMID = 20717684.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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26. Dalit A, Karen M, Alexander M: Congenital desmoid tumor of the cheek: a clinicopathological case report. Eplasty; 2009;9:e52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital desmoid tumor of the cheek: a clinicopathological case report.
  • OBJECTIVE: Desmoid tumors are rare benign neoplasms of fibroblastic origin, frequently presenting in the abdomen of adult patients.
  • METHODS: We report a girl with a desmoid tumor of her cheek, which was present at birth.
  • RESULTS: The tumor was treated by surgical excision, with no additional treatment, other than follow-up.
  • No recurrence of the tumor was witnessed 15 months following surgical excision.
  • SUMMARY: Radical surgical treatment with tumor excision, sometimes accompanied by radiotherapy, is the current standard therapy for infantile desmoid tumors.

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  • (PMID = 20011031.001).
  • [ISSN] 1937-5719
  • [Journal-full-title] Eplasty
  • [ISO-abbreviation] Eplasty
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2779781
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27. Schrock A, Gutgemann I, Keiner S: [Castleman's disease in ear, nose, and throat practice]. HNO; 2007 May;55 Suppl 1:E29-32
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  • [Title] [Castleman's disease in ear, nose, and throat practice].
  • Castleman's disease, also called angiofollicular lymph node hyperplasia or benign giant lymphoma, is a rare lymphoproliferative disorder of unknown etiology.
  • Due to the lack of tumor-specific clinical, biochemical, and radiological features, final diagnosis of Castleman's disease depends on histopathology.
  • Surgical tumor resection is the treatment of choice for localized disease.
  • Therefore, early invasive removal and histopathological differentiation from neoplasia is mandatory.
  • On admission, the patient complained of a painless pharyngeal tumor mass and ipsilateral lymph node swelling.
  • After tumor resection, histopathological examination, and clinical staging, localized Castleman's disease was diagnosed (hyaline vascular subtype).
  • [MeSH-major] Giant Lymph Node Hyperplasia / diagnosis. Giant Lymph Node Hyperplasia / surgery. Otolaryngology / methods. Pharyngeal Neoplasms / diagnosis. Pharyngeal Neoplasms / surgery

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  • (PMID = 17262216.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 16
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28. Skrivan J, Zvĕrina E, Kluh J, Chovanec M, Pádr R: Our experience with surgical treatment of tympanojugular pragangliomas. Prague Med Rep; 2010;111(1):25-34
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  • Tympanojugular paragangliomas are benign and slow growing lesions of the lateral skull base.
  • According to the benign character of the tumour, radicality is not always the highest goal, since a radical removal may be compromised by a high postoperative morbidity.
  • [MeSH-major] Ear Neoplasms / surgery. Glomus Jugulare Tumor / surgery. Paraganglioma, Extra-Adrenal / surgery

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  • (PMID = 20359435.001).
  • [ISSN] 1214-6994
  • [Journal-full-title] Prague medical report
  • [ISO-abbreviation] Prague Med Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Czech Republic
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29. Moser A, Hoffmann KM, Walch C, Sovinz P, Lackner H, Schwinger W, Benesch M, Fritz G, Urban C: Intracranial reparative giant cell granuloma secondary to cholesteatoma in a 15-year-old girl. J Pediatr Hematol Oncol; 2008 Dec;30(12):935-7
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  • A 15-year-old girl presented with pain in the right ear and acute onset of total peripheral facial nerve palsy.
  • A first biopsy led to the diagnosis of intracranial giant cell reparative granuloma (GCRG), a rare benign tumor of the bone or soft tissue that can show expansive growth.
  • Total surgical excision revealed a cholesteatoma central to the GCRG originating from the right middle ear and mastoid.
  • [MeSH-major] Bone Diseases / etiology. Cholesteatoma, Middle Ear / complications. Granuloma, Giant Cell / etiology. Temporal Bone

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  • (PMID = 19131785.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 144O8QL0L1 / Diclofenac
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30. Jakobiec FA, Colby K, Bajart AM, Saragas SJ, Moulin A: Immunohistochemical studies of atypical conjunctival melanocytic nevi. Arch Ophthalmol; 2009 Aug;127(8):970-80
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  • Ki-67 was the most valuable immunohistochemical adjunct to morphology for the diagnosis of these benign variant conjunctival nevi, because melanomas display a much higher proliferation index (>10% nuclear positivity among all cells counted) than the current nevi (approximately 1%).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Conjunctival Neoplasms / metabolism. Neoplasm Proteins / metabolism. Nevus, Blue / metabolism. Nevus, Pigmented / metabolism
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Antigens, Neoplasm / metabolism. Female. Humans. Immunoenzyme Techniques. Ki-67 Antigen / metabolism. MART-1 Antigen. Male. Melanoma-Specific Antigens. Middle Aged. Muramidase / metabolism. Retrospective Studies. S100 Proteins / metabolism. Young Adult

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  • (PMID = 19667333.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 3.2.1.17 / Muramidase
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31. Ludlow A, Yee KO, Lipman R, Bronson R, Weinreb P, Huang X, Sheppard D, Lawler J: Characterization of integrin beta6 and thrombospondin-1 double-null mice. J Cell Mol Med; 2005 Apr-Jun;9(2):421-37
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  • Furthermore, the beta6-null and double-null mice displayed a significant elevation in benign and malignant cancers.
  • Stomach papillomas, squamous cell carcinomas of the ear and stomach, and adenocarcinomas of the lungs, vagina/cervix and colon were observed with the highest frequency.
  • They also indicate that alphavbeta6 functions as a tumor suppressor gene and that activation of TGFbeta by TSP-1 and alphavbeta6 contributes to normal tissue architecture and function.
  • [MeSH-major] Inflammation / genetics. Integrin beta Chains / genetics. Neoplasms / genetics. Thrombospondin 1 / genetics
  • [MeSH-minor] Alopecia / genetics. Animals. Cardiomyopathies / genetics. Cardiomyopathies / pathology. Crosses, Genetic. Epithelium / pathology. Female. Genital Diseases, Female / genetics. Genital Diseases, Female / pathology. Hyperplasia / genetics. Hyperplasia / pathology. Longevity / genetics. Lung Diseases / genetics. Lung Diseases / pathology. Male. Mice. Mice, Knockout. Mice, Mutant Strains. Neoplasms, Squamous Cell / genetics. Neoplasms, Squamous Cell / pathology. Phenotype. Pneumonia / genetics. Pneumonia / pathology. Stomach Diseases / genetics. Stomach Diseases / pathology. Transforming Growth Factor beta / metabolism

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  • (PMID = 15963261.001).
  • [ISSN] 1582-1838
  • [Journal-full-title] Journal of cellular and molecular medicine
  • [ISO-abbreviation] J. Cell. Mol. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA86410; United States / NCI NIH HHS / CA / CA92644; United States / NHLBI NIH HHS / HL / HL53949; United States / NHLBI NIH HHS / HL / HL68003
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Integrin beta Chains; 0 / Thrombospondin 1; 0 / Transforming Growth Factor beta; 0 / integrin beta6
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32. Nishi SP, Brey NV, Sanchez RL: Dermal nodular fasciitis: three case reports of the head and neck and literature review. J Cutan Pathol; 2006 May;33(5):378-82
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  • Nodular fasciitis is a benign reactive myofibroblastic proliferative process of unknown etiology.
  • Diagnosis is often a challenge because it may be confused with a malignant tumor due to its aggressive clinical behavior and histological features.
  • There have been five separate reports documenting rare cases of dermal nodular fasciitis in the dermatopathology literature and one case series involving 28 of 50 dermal variants from the external ear region.
  • [MeSH-minor] Adolescent. Adult. Diagnosis, Differential. Female. Head and Neck Neoplasms / pathology. Humans. Immunohistochemistry. Male. Skin Neoplasms / pathology

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  • (PMID = 16640547.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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33. Kwon H, Kim HY, Jung SN, Sohn WI, Yoo G: Extraskeletal chondroma in the auricle. J Craniofac Surg; 2010 Nov;21(6):1990-1
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  • Extraskeletal chondroma is a rare benign tumor that develops in soft tissues, and histologically, it is a lobulated nodule surrounded by a fibrous capsule, and the inside consists of mature cartilage cells and diffuse hyalinized matrix.
  • [MeSH-major] Chondroma / diagnosis. Ear Auricle / pathology. Ear Neoplasms / diagnosis

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  • (PMID = 21119479.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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34. Park YH, Kim SW, Cho SH, Choi YW: Nasopharyngeal glioma causing respiratory distress in a neonate: transoral endoscopic excision. Ear Nose Throat J; 2010 May;89(5):E11-3
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  • Nasal gliomas are rare, benign, congenital midline tumors made up of heterotopic neuroglial tissue.
  • Preoperative diagnostic imaging is essential to delineate the exact location, limits, and extensions of the tumor and thus to determine the appropriate surgical approach.
  • [MeSH-major] Endoscopy / methods. Glioma / complications. Glioma / surgery. Nasopharyngeal Neoplasms / complications. Nasopharyngeal Neoplasms / surgery. Respiratory Distress Syndrome, Newborn / etiology

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  • (PMID = 20461669.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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35. Ozcan C, Apa DD, Vayisoglu Y, Görür K: Unilateral parotid gland involvement with synchronous multiple Basal cell adenomas. J Craniofac Surg; 2007 Nov;18(6):1470-3
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  • Basal cell adenoma (BCA) is a rare benign epithelial tumor of the salivary gland.
  • The most commonly seen multiple tumor unilaterally or bilaterally is the Warthin's tumor.
  • A 65-year-old woman with a painful, slowly enlarging mass in front of the left ear, which was present for 6 months, was evaluated.
  • More extensive excision of the parotid gland tumor, careful macroscopic perioperative examination of the surgical specimen, and histologic evaluation of all surgical specimens might be necessary for reducing revision operations and surgical complications.
  • [MeSH-major] Adenoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17993904.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Durr ML, Agrawal N, Saunders JR, Ha PK: Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review. Ear Nose Throat J; 2010 Jan;89(1):34-7
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  • Lipomas are benign mesenchymal tumors that are often found in the head and neck.
  • The tumor was successfully removed via an endoscopic laser resection.
  • [MeSH-major] Laryngeal Neoplasms / epidemiology. Laryngeal Neoplasms / pathology. Lipoma / pathology. Lipomatosis / epidemiology

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  • (PMID = 20155698.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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37. Markert E, Gruber-Moesenbacher U, Porubsky C, Popper HH: Lung osteoma--a new benign lung lesion. Virchows Arch; 2006 Jul;449(1):117-20
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  • [Title] Lung osteoma--a new benign lung lesion.
  • Tumors with osseous elements can be found, such as hamartoma and amyloid tumor, and reactive lesions such as osseous metaplasia.
  • A 39-year-old male patient was treated for multiple myeloma and got a bone marrow transplantation 2 years and a few months before he presented with a solitary well-circumscribed tumor in the right middle lobe.
  • The tumor presented with a fibrous capsule and consisted of mature bone trabecules.
  • Within the tumor, fatty tissue was seen.
  • This tumor might have been induced by circulating stem cells; however, due to autologous bona marrow transplantation, this cannot be proven.
  • [MeSH-major] Bone Neoplasms / pathology. Lung Neoplasms / pathology. Neoplasms, Second Primary / pathology. Ossification, Heterotopic / pathology. Osteoma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Bone Marrow Transplantation. Diagnosis, Differential. Hamartoma / diagnosis. Humans. Immunohistochemistry. Male. Multiple Myeloma / pathology. Multiple Myeloma / therapy. Osteonectin / analysis

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  • (PMID = 16639606.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Osteonectin
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38. Benoit MM, Handzel O, McKenna MJ, Deschler DG: A 42-year-old man with facial nerve weakness and multiple recurrent pleomorphic adenoma. Otol Neurotol; 2010 Sep;31(7):1157-9
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  • CONCLUSION: Facial nerve weakness caused by a benign salivary gland tumor is rare.
  • [MeSH-major] Adenoma, Pleomorphic / complications. Facial Paralysis / etiology. Parotid Neoplasms / complications
  • [MeSH-minor] Adult. Humans. Immunosuppressive Agents / therapeutic use. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Temporal Bone / pathology. Tomography, X-Ray Computed

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  • (PMID = 20657328.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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39. Zatonski T, Bolanowski M, Skrzypek A, Morawska-Kochman M, Kaluzny M, Zatonska K, Moron K, Badowski R, Krecicki T: Evaluation of temporal bone computed tomography and paranasal sinuses magnetic resonance images in acromegalic patients. Neuro Endocrinol Lett; 2010;31(6):796-800
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  • OBJECTIVE: Acromegaly is a rare disease, which symptoms are caused by excess secretion of a growth hormone (GH) from the anterior pituitary benign tumor - adenoma.
  • 2. CT of temporal bone did not reveal structural changes of internal and median ear.

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  • (PMID = 21206436.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Sweden
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40. Ekşi E, Oztop I: Nerve sheath myxoma of the upper lip: a case report. Kulak Burun Bogaz Ihtis Derg; 2010 Nov-Dec;20(6):318-20
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  • Nerve sheath myxoma is a benign tumor that rarely occurs in the lip area.
  • [MeSH-major] Lip Neoplasms / surgery. Neurothekeoma / surgery
  • [MeSH-minor] Adult. Cell Division. Female. Humans. Neoplasm Recurrence, Local / prevention & control. S100 Proteins / analysis. Treatment Outcome

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  • (PMID = 20961288.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / S100 Proteins
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41. Vo QT, Wolf JA, Turner JW, Murkis M, Saw D, Shemen LJ: Solitary fibrous tumor of the parapharyngeal space. Ear Nose Throat J; 2007 Aug;86(8):502-5
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  • [Title] Solitary fibrous tumor of the parapharyngeal space.
  • Solitary fibrous tumors are benign neoplasms of mesenchymal origin.
  • We report a case of solitary fibrous tumor of the parapharyngeal space.
  • Microscopically, the tumor contained spindle cells with areas of marked hypercellularity without a definitepattern.
  • Consistent with a benign lesion, there were few mitoses and no necrosis.
  • The tumor cells stained strongly positive for CD34 and vimentin.
  • [MeSH-major] Hemangiopericytoma / pathology. Hemangiopericytoma / surgery. Neoplasms, Fibrous Tissue / pathology. Neoplasms, Fibrous Tissue / surgery. Otorhinolaryngologic Surgical Procedures / methods. Pharyngeal Neoplasms / pathology. Pharyngeal Neoplasms / surgery

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  • (PMID = 17915675.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Madani G, Beale T: Tumors of the salivary glands. Semin Ultrasound CT MR; 2006 Dec;27(6):452-64
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  • This article reviews the role of imaging in the management of tumors of the salivary glands, discussing tumor localization, extent, and, where possible, characterization.
  • The relative benefits of the different modalities and the typical features of benign and malignant lesions are discussed for each modality.
  • [MeSH-major] Diagnostic Imaging. Salivary Gland Neoplasms / diagnosis

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  • (PMID = 17233228.001).
  • [ISSN] 0887-2171
  • [Journal-full-title] Seminars in ultrasound, CT, and MR
  • [ISO-abbreviation] Semin. Ultrasound CT MR
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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43. Shekarkhar MJ, Tabei SZ, Kumar PV, Hashemi SB: Cytologic findings in calcifying epithelial odontogenic tumor: a case report. Acta Cytol; 2005 Sep-Oct;49(5):533-6
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  • [Title] Cytologic findings in calcifying epithelial odontogenic tumor: a case report.
  • BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT), or Pindborg's tumor, is a rare, benign, odontogenic neoplasm first described by Pindborg in 1955.
  • CASE: A 62-year-old woman was referred to the ear, nose and throat clinic with a right maxillary mass.
  • CONCLUSION: FNA findings of calcifying epithelial odontogenic tumor have been described rarely.
  • The clusters of epithelial cells with prominent nucleoli are mistaken for features of a malignant tumor.
  • [MeSH-major] Calcinosis / pathology. Epithelial Cells / pathology. Jaw Neoplasms / pathology. Maxillary Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology. Palatal Neoplasms / pathology

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  • (PMID = 16334032.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Jakobiec FA, Nguyen J, Bhat P, Fay A: MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):413-5
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  • [Title] MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit.
  • PURPOSE: To distinguish, in a 36-year-old man, an atypical lipomatous neoplasm/well-differentiated liposarcoma from a spindle cell lipoma in a recurrent orbital tumor.
  • RESULTS: MDM2 gene amplification was discovered in the CD34 tumor cells.
  • CONCLUSION: Well-differentiated liposarcoma is a slow growing, infiltrative, and nonmetastasizing neoplasm that is microscopically and diagnostically challenging.
  • It can be reliably separated from a benign spindle cell or an atypical lipoma by using the markers MDM2 and Ki-67.
  • [MeSH-major] Biomarkers, Tumor / analysis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbital Neoplasms / diagnosis. Proto-Oncogene Proteins c-mdm2 / analysis

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  • (PMID = 20639786.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / S100 Proteins; 9013-56-3 / Factor XIII; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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45. Jana AK, Jaswal A, Sikder B, Jana U, Nandi TK: Surgical management of parapharyngeal tumors - our experience. Indian J Otolaryngol Head Neck Surg; 2008 Dec;60(4):345-8
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  • Fifteen cases of parapharyngeal tumors treated surgically in ENT department of Calcutta National Medical College in last 2 years were included, 80% cases were of benign tumors, most common being schwannomas.
  • The study gives an overview regarding the surgical approach, based upon the extent and histology of the tumor and transcervical approach was found to be most efficient for all practical purpose.

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  • (PMID = 23120578.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
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  • [Other-IDs] NLM/ PMC3476807
  • [Keywords] NOTNLM ; Parapharyngeal tumors / Surgical management
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46. Roche PH, Mercier P, Sameshima T, Fournier HD: Surgical anatomy of the jugular foramen. Adv Tech Stand Neurosurg; 2008;33:233-63
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  • Surgical exposure of the JF is usually justified by the removal of benign tumors that grow in this region.
  • In the second step, the external auditory canal is transsected and the intrapetrous facial nerve is mobilized, giving more exposure of the carotid canal and middle ear cavity.
  • Using the same dissection of the soft tissues from a lateral trajectory, these three approaches bring solutions to the radical removal of distinct tumor extensions.
  • [MeSH-major] Cranial Fossa, Posterior / pathology. Neurilemmoma / pathology. Skull Base Neoplasms / pathology

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  • (PMID = 18383816.001).
  • [ISSN] 0095-4829
  • [Journal-full-title] Advances and technical standards in neurosurgery
  • [ISO-abbreviation] Adv Tech Stand Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
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47. Modlin IM, Shapiro MD, Kidd M: An analysis of rare carcinoid tumors: clarifying these clinical conundrums. World J Surg; 2005 Jan;29(1):92-101
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  • Carcinoid tumors are distinct neuroendocrine neoplasms with characteristic histological, clinical, and biological properties.
  • The diminution of the likelihood of inadvertently neglecting these often benign, indolent neoplasms that are well known to metastasize if unaddressed would represent an important advance.
  • [MeSH-major] Carcinoid Tumor / surgery
  • [MeSH-minor] Bile Duct Neoplasms / surgery. Bile Ducts, Extrahepatic. Breast Neoplasms / surgery. Esophageal Neoplasms / surgery. Female. Gallbladder Neoplasms / surgery. Humans. Laryngeal Neoplasms / surgery. Liver Neoplasms / surgery. Male. Ovarian Neoplasms / surgery. Pancreatic Neoplasms / surgery. Testicular Neoplasms / surgery. Uterine Cervical Neoplasms / surgery

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  • (PMID = 15599742.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 80
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48. Persaud R, Tudge S, Amonoo-Kuofi K, Beale T, O'Flynn P: Parapharyngeal granular cell tumour: a unique surgical challenge. J Laryngol Otol; 2005 Jan;119(1):68-70
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  • It is typically benign but up to seven per cent may be malignant.
  • The authors report a case of a 49-year-old African woman with an oro-naso-parapharyngeal granular cell neoplasm causing mild dysphagia.
  • [MeSH-major] Granular Cell Tumor / surgery. Pharyngeal Neoplasms / surgery

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  • (PMID = 15807973.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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49. Durden FL Jr, Moore CE, Muller S: Verrucous carcinoma of the paranasal sinuses: a case report. Ear Nose Throat J; 2010 Jul;89(7):E21-3
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  • The tumor grows locally invasive but is histologically benign and metastasizes rarely.
  • [MeSH-major] Carcinoma, Verrucous / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Biopsy. Endoscopy. Humans. Male. Middle Aged. Nasal Cavity / pathology. Nasal Cavity / radiation effects. Nasal Cavity / surgery. Neoplasm Invasiveness. Neoplasm Staging. Orbital Neoplasms / pathology. Orbital Neoplasms / radiotherapy. Orbital Neoplasms / surgery. Skull / pathology. Skull / radiation effects. Skull / surgery. Skull Neoplasms / pathology. Skull Neoplasms / radiotherapy. Skull Neoplasms / surgery

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  • (PMID = 20628974.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Sterker I, Hagert-Winkler A, Gradistanac T, Frerich B: [Granular cell tumor of the orbit]. Ophthalmologe; 2007 Sep;104(9):803-5
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  • [Title] [Granular cell tumor of the orbit].
  • Granular cell tumor (GCT, Abrikossoff tumor) is an extremely rare, benign tumor with a neurogenic origin occurring most commonly in the upper aerodigestive tract.
  • [MeSH-major] Granular Cell Tumor. Orbital Neoplasms

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  • (PMID = 17440732.001).
  • [ISSN] 0941-293X
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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51. De Gabory L, Deminière C, Stoll D: [Immunohistochemistry expression of 3 markers (CEA, UEA-I and Ki-67) in nasal inverted papillomas]. Rev Laryngol Otol Rhinol (Bord); 2008;129(3):159-65
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  • [Transliterated title] Expression immunohistochimique de l'ACE, de l'UEA-I et du Ki-67 dans les papillomes inversés naso-sinusiens.
  • OBJECTIVES: Immunohistochemistry evaluation of the expression of degeneration and proliferation markers of the benign form of Schneiderian inverted papillomas in the ORL sphere, in the nondysplastic, dysplastic and degenerated forms.
  • MATERIALS AND METHOD: 44 surgical specimens were analyzed in two groups: A= 33 benign and B= 11 degenerated.
  • A simultaneous bipolar localization belonged to the two groups (nasal, benign and otologic malignant).
  • But, no difference existed between groups A and B, the various sub-groups and the benign specific localizations.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Ki-67 Antigen / analysis. Nose Neoplasms / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology. Plant Lectins / analysis. Sphenoid Sinus / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Child. Diagnosis, Differential. Ear Neoplasms / pathology. Ear Neoplasms / surgery. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nasal Mucosa / pathology. Nasal Polyps / pathology. Nasal Polyps / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Prognosis. Reference Values

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  • (PMID = 19694158.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Plant Lectins; 0 / Ulex europaeus lectins
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52. Fleiner F, Jumah M, Göktas O: Cancer of the external auditory canal-diagnostic and treatment. Indian J Otolaryngol Head Neck Surg; 2009 Dec;61(4):270-4
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  • BACKGROUND: Ear squamous cell carcinoma (SCC) is a tumor with a poor prognosis, due to a late initial diagnosis because of a concealment by primarily benign symptoms and due to the unfavorable localization including the infiltration of important structures such as the middle ear, mandibular joint or dura.
  • CONCLUSION: The prognosis for ear SCC primarily depends on early clinical and histopathological diagnostics and requires a sufficient and standardized staging to determine the therapy involving surgery and radiochemotherapy.

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  • (PMID = 23120649.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450079
  • [Keywords] NOTNLM ; Carcinoma of the external auditory canal / Prognosis / Radiation treatment / Squamous cell carcinoma / Surgery
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53. Oktay MF, Aşkar I, Yildirim M, Topçu I, Meriç F: Tuberculous parotitis: a review of seven cases. Kulak Burun Bogaz Ihtis Derg; 2007;17(5):272-7
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  • All the patients had a clinical suspicion of a parotid gland tumor.
  • Computed tomography or magnetic resonance imaging obtained in five patients showed mass formation suggesting a benign parotid gland tumor.
  • CONCLUSION: Tuberculosis of the parotid gland should be considered in the differential diagnosis of patients presenting with a solitary tumor in the parotid gland.

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  • (PMID = 18187986.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Antitubercular Agents
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54. Keleş E, Akpolat N, Alpay HC, Tazegül A: [A rare tumor in a newborn: congenital epulis]. Kulak Burun Bogaz Ihtis Derg; 2005;14(3-4):92-5
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  • [Title] [A rare tumor in a newborn: congenital epulis].
  • Congenital epulis is a benign tumor.
  • [MeSH-major] Gingival Diseases / diagnosis. Gingival Neoplasms / diagnosis

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  • (PMID = 16227732.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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55. Bennett M, Haynes DS: Surgical approaches and complications in the removal of vestibular schwannomas. Otolaryngol Clin North Am; 2007 Jun;40(3):589-609, ix-x
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  • Vestibular schwannomas are benign tumors that usually originate from the balance portion of cranial nerve VIII.
  • Although the ultimate goal in treatment of vestibular schwannomas is preservation of life, the best option for each patient depends on symptoms, tumor size, tumor location, and the patient's general health and age.
  • The goal of surgery is complete eradication of tumor with preservation of hearing and facial nerve function when possible.
  • [MeSH-major] Ear Neoplasms / surgery. Neuroma, Acoustic / surgery. Otologic Surgical Procedures / methods
  • [MeSH-minor] Cerebrospinal Fluid Otorrhea / epidemiology. Cerebrospinal Fluid Otorrhea / etiology. Facial Nerve Diseases / epidemiology. Facial Nerve Diseases / etiology. Headache / epidemiology. Headache / etiology. Humans. Meningitis / epidemiology. Meningitis / etiology. Neoplasm Recurrence, Local. Postoperative Complications. Postural Balance / physiology. Tinnitus / epidemiology. Tinnitus / etiology

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  • (PMID = 17544697.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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56. Lim JH, Jono H, Koga T, Woo CH, Ishinaga H, Bourne P, Xu H, Ha UH, Xu H, Li JD: Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PLoS One; 2007 Oct 10;2(10):e1032
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  • [Title] Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.
  • The deubiquitinating enzyme cylindromatosis (CYLD), loss of which was originally reported to cause a benign human syndrome called cylindromatosis, has been identified as a key negative regulator for NF-kappaB in vitro.
  • Our data demonstrated that CYLD is induced by NTHi in the middle ear and lung of mice.

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  • (PMID = 17925880.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC004562; United States / NIDCD NIH HHS / DC / R01 DC005843; United States / NIDCD NIH HHS / DC / DC004562; United States / NIDCD NIH HHS / DC / DC005843
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / NF-kappa B; 0 / TNF Receptor-Associated Factor 6; 0 / TRAF7 protein, human; 0 / Traf7 protein, mouse; 0 / Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; EC 3.1.2.15 / CYLD protein, mouse; EC 3.4.22.- / Cysteine Endopeptidases
  • [Other-IDs] NLM/ PMC2001183
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57. Senchak AJ, Dann M, Cable B, Bessinger G: Successful treatment of cutaneous hemangioma of infancy with topical imiquimod 5%: a report of 3 cases. Ear Nose Throat J; 2010 Mar;89(3):E21-5
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  • Hemangioma of infancy is the most common benign tumor of childhood.
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Hemangioma / drug therapy. Hemangioma / pathology. Skin Neoplasms / drug therapy. Skin Neoplasms / pathology

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  • (PMID = 20229466.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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58. Zhang F, Wang Y, Dai C, Chi F, Zhou L, Chen B, Li H: [Clinical experience in facial nerve tumors: a review of 27 cases]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jan;24(1):4-7
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  • OBJECTIVE: To analyze the clinical manifestations and the diagnosis of the facial nerve tumor according to the clinical information, and evaluate the different surgical approaches depending on tumor location.
  • During the course of the disease, 23 patients (85.2%) suffered facial paralysis, both hearing loss and tinnitus affected 11 (40.7%) cases, 5 (18.5%) manifested infra-auricular mass and the others showed some of otalgia or vertigo or ear fullness or facial numbness/twitches.
  • CONCLUSION: Facial nerve tumor is a rare and benign lesion, and has numerous clinical manifestations.
  • [MeSH-major] Cranial Nerve Neoplasms. Facial Nerve Diseases

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  • (PMID = 20235447.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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59. Boulos PR, Knoepp SM, Rubin PA: Green bone. Arch Ophthalmol; 2007 Mar;125(3):380-6
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  • OBJECTIVE: To describe the unusual finding of yellow-green-colored bone during routine orbital surgery, to detail its investigation, and to demonstrate its benign nature.
  • RESULTS: Yellow-green bone was encountered in 3 patients during orbital tumor excision or orbital fracture repair procedures.
  • In all cases, absence of neoplasia was demonstrated histologically.
  • [MeSH-minor] Adult. Color. Humans. Male. Microscopy, Fluorescence. Microscopy, Ultraviolet. Middle Aged. Orbital Fractures / surgery. Orbital Neoplasms / radiography. Orbital Neoplasms / surgery. Spectrophotometry, Ultraviolet. Tomography, X-Ray Computed

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  • (PMID = 17353410.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protein Synthesis Inhibitors; F8VB5M810T / Tetracycline
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60. Zehlicke T, Punke C, Boltze C, Pau HW: Transient facial palsy in two cases of benign, very rare middle ear tumors (carcinoid tumor and myxoma). Neurologist; 2008 Jan;14(1):52-5
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  • [Title] Transient facial palsy in two cases of benign, very rare middle ear tumors (carcinoid tumor and myxoma).
  • OBJECTIVE: Presentation of the clinical features of 2 very rare middle ear tumors in which the guiding symptom was facial palsy.
  • MATERIAL AND METHODS: Illustrative case reports about a myxoma and a carcinoid tumor of the middle ear associated with peripheral facial palsy.
  • Moreover, both tumor entities are typically found in organs other than the ear; if located in the middle ear, those neoplasms grow rather superficially.
  • In those cases, a surgical exposure of the middle ear is indicated.
  • We report the cases of 2 rare middle ear tumors causing facial palsy.
  • [MeSH-major] Carcinoid Tumor / pathology. Ear Neoplasms / pathology. Ear, Middle / pathology. Facial Paralysis / pathology. Myxoma / pathology

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  • (PMID = 18195660.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. Amin A, Monabati A, Kumar PV, Hashemi SB: Nasal glioma (neuroglial heterotopia) mimicking an astrocytoma: case report. Ear Nose Throat J; 2005 Oct;84(10):657-8
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  • Nasal glioma is a rare benign tumor that usually occurs during infancy.
  • [MeSH-major] Astrocytoma / diagnosis. Glioma / diagnosis. Neuroglia / pathology. Nose Neoplasms / diagnosis

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  • (PMID = 16382748.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Kloek CE, Bilyk JR, Pribitkin EA, Rubin PA: Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex. Ophthalmology; 2006 Jul;113(7):1214-9
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  • [Title] Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex.
  • The purpose of this study was to investigate outcomes in 5 patients with benign-appearing but symptomatic tumors located in the intraconal portion of the orbital apex in which orbital decompression was performed as an alternative management strategy to resection.
  • PARTICIPANTS: Five patients were diagnosed with a compressive optic neuropathy secondary to a benign-appearing tumor at the orbital apex.
  • None of the patients had the tumor biopsied or resected.
  • CONCLUSIONS: Orbital decompression is a therapeutic option for patients with compressive optic neuropathies from benign orbital apex tumors, offering potential improvement in optic nerve function while sparing morbidity from attempts at surgical resection.
  • [MeSH-major] Decompression, Surgical. Nerve Compression Syndromes / surgery. Optic Nerve Diseases / surgery. Orbit / surgery. Orbital Neoplasms / surgery

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  • [CommentIn] Ophthalmology. 2007 Mar;114(3):619-20; author reply 620-1 [17324707.001]
  • (PMID = 16815404.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Kim HY, Jung SN, Kwon H, Sohn WI, Moon SH: Angiomyoma in the buccal space. J Craniofac Surg; 2010 Sep;21(5):1634-5
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  • Angiomyoma is a rare benign tumor originated from vascular smooth muscle cells, in other words, the tunica media, and the characteristic is the detection of numerous blood vessels together with spindle-shape smooth muscle cells.
  • In the head and neck area, it is developed most frequently in the larynx and the turbinates, and in addition, the development in the oral cavity (lip, hard palate, tonsil), nose, ear, cheek, parotid gland, and submandibular region has been reported.
  • [MeSH-major] Angiomyoma / surgery. Mouth Neoplasms / surgery

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  • (PMID = 20856064.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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64. Lessell S, Kim JW, Hatton MP, Stemmer-Rachamimov A, Thiagalingham S, Rubin PA: Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma. J Neuroophthalmol; 2007 Jun;27(2):104-6
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  • A 28-year-old man with a biopsy-proven benign intraorbital optic nerve sheath meningioma developed recurrent clinical manifestations of ipsilateral retrobulbar inflammation 9 years after undergoing postoperative radiation therapy.
  • Debulking of the tumor 11 years after the original surgery again revealed no pathologic signs of inflammation.
  • Whether growth of tumor, surgery, radiation, or edema triggered the inflammatory manifestations is unclear.
  • [MeSH-major] Inflammation / complications. Meningeal Neoplasms / complications. Meningioma / complications. Optic Nerve Neoplasms / complications

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  • (PMID = 17548993.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. McKenna M, Brodsky L: Extraesophageal acid reflux and recurrent respiratory papilloma in children. Int J Pediatr Otorhinolaryngol; 2005 May;69(5):597-605
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Recurrent respiratory papillomatosis (RRP) is a benign infectious disease which is caused by the human papilloma virus (HPV).
  • [MeSH-major] Gastroesophageal Reflux / complications. Gastroesophageal Reflux / diagnosis. Laryngeal Neoplasms / complications. Neoplasm Recurrence, Local / complications. Papilloma / complications
  • [MeSH-minor] Airway Obstruction / etiology. Airway Obstruction / therapy. Child. Child, Preschool. Humans. Male. Papillomaviridae. Papillomavirus Infections / complications. Papillomavirus Infections / therapy. Severity of Illness Index. Tumor Virus Infections / complications. Tumor Virus Infections / therapy

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  • [CommentIn] Int J Pediatr Otorhinolaryngol. 2006 Apr;70(4):757-8; author reply 759 [16242786.001]
  • (PMID = 15850681.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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66. Medina EA, Arias VL: [Middle ear adenoma]. Biomedica; 2009 Sep;29(3):348-53
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  • [Title] [Middle ear adenoma].
  • [Transliterated title] Adenoma del oído medio.
  • Middle ear neoplasms are rare lesions and difficult to diagnose due to limited information about their biology and the lack of standard criteria for their analysis.
  • Herein, a middle ear neoplasm is described that became apparent because of its appearance in the external ear duct as it protruded from the middle ear through the eardrum.
  • Following resection, the specimen was determined to be a benign epithelial tumor.
  • Absence of adequate clinical information complicated the diagnosis; therefore,histochemistry and immunohistochemistry analyses were necessary to reach the final diagnosis of middle ear adenoma.
  • [MeSH-major] Adenoma. Ear Neoplasms. Ear, Middle

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  • (PMID = 20436986.001).
  • [ISSN] 0120-4157
  • [Journal-full-title] Biomédica : revista del Instituto Nacional de Salud
  • [ISO-abbreviation] Biomedica
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Colombia
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67. Thuesen AD, Jakobsen J, Nepper-Rasmussen J: [Treatment of juvenile angiofibroma with particle embolization and endoscopic surgery]. Ugeskr Laeger; 2005 Aug 22;167(34):3167-9
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  • INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood.
  • The embolization, which was carried out in the radiotherapy department, was done with polyvinyl alcohol particles in the vessels that supply the tumor.
  • The operation was then performed in the ear, nose and throat department of OUH.
  • The tumor was removed endoscopically in all cases in which it was possible.
  • [MeSH-major] Angiofibroma / therapy. Embolization, Therapeutic / methods. Nasopharyngeal Neoplasms / therapy

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  • [CommentIn] Ugeskr Laeger. 2005 Nov 21;167(47):4482 [16305784.001]
  • (PMID = 16117915.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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68. Yates CW, Weinberg M, Packer MJ, Jacob A: Fatal case of tumor-associated hemorrhage in a large vestibular schwannoma. Ann Otol Rhinol Laryngol; 2010 Jun;119(6):402-5
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  • [Title] Fatal case of tumor-associated hemorrhage in a large vestibular schwannoma.
  • Vestibular schwannomas are benign neoplasms that arise from Schwann cells of the eighth cranial nerve.
  • During this procedure, a biopsy specimen was obtained, showing benign vestibular schwannoma.

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  • (PMID = 20583739.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticoagulants; 5Q7ZVV76EI / Warfarin
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69. Thakur JS, Mohindroo NK, Mohindroo S, Sharma DR, Thakur A: Pleomorphic adenoma of minor salivary gland with therapeutic misadventure: a rare case report. BMC Ear Nose Throat Disord; 2010;10:2
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  • BACKGROUND: The benign tumors of nasopharynx are least encountered tumors in otolaryngology, as nasopharynx is considered one of notorious anatomical site for the malignant tumors.
  • On CT scan, this tumor was quite big and extending to the parapharyngeal space.
  • The excision biopsy of tumor revealed it as pleomorphic adenoma.
  • We found only five published reports on this tumor arising from nasopharynx.
  • DISCUSSION AND CONCLUSION: Although, in this case report exact origin of the tumor could not be ascertained as it also appeared to be a parapharyngeal tumor but we kept the possibility of a nasopharyngeal tumor on the basis of clinical features.
  • It can be misdiagnosed as malignant epithelial tumor on histopathology.
  • A possibility of benign tumor should always be kept in nasopharyngeal growth with no evidence of metastasis, and histopathological diagnosis of growth should be available before any definitive treatment.

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  • (PMID = 20157428.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2821363
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70. Gupta SC, Sachin J, Savyasachi S, Ritesh J, Neha G, Singh HP: Solitary nasal schwannoma clinically presenting as an angiofibroma of the nasopharynx. Ear Nose Throat J; 2010 Jul;89(7):E28-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign schwannomas of the nasal cavity are rare.
  • The tumor was removed via a transpalatal approach.
  • [MeSH-major] Angiofibroma / diagnosis. Nasal Septum / pathology. Nasopharyngeal Neoplasms / diagnosis. Neurilemmoma / pathology. Nose Neoplasms / pathology

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  • (PMID = 20628976.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Ghanooni R, Decaestecker C, Simon P, Gabius HJ, Hassid S, Choufani G: Characterization of patterns of expression of protein kinase C-alpha, -delta, -eta, -gamma and -zeta and their correlations to p53, galectin-3, the retinoic acid receptor-beta and the macrophage migration inhibitory factor (MIF) in human cholesteatomas. Hear Res; 2006 Apr;214(1-2):7-16
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  • Cholesteatoma is a benign disease characterized by the presence of an unrestrained growth and the accumulation of keratin in the middle ear cavity.
  • [MeSH-major] Cholesteatoma, Middle Ear / enzymology. Galectin 3 / analysis. Macrophage Migration-Inhibitory Factors / analysis. Protein Kinase C / analysis. Retinoid X Receptor beta / analysis. Tumor Suppressor Protein p53 / analysis

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  • (PMID = 16513304.001).
  • [ISSN] 0378-5955
  • [Journal-full-title] Hearing research
  • [ISO-abbreviation] Hear. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Galectin 3; 0 / Macrophage Migration-Inhibitory Factors; 0 / Retinoid X Receptor beta; 0 / Tumor Suppressor Protein p53; EC 2.7.11.13 / Protein Kinase C
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72. Bambakidis NC, Rodrigue T, Megerian CA, Ratcheson RA: Endolymphatic sac tumor metastatic to the spine. Case report. J Neurosurg Spine; 2005 Jul;3(1):68-70
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  • [Title] Endolymphatic sac tumor metastatic to the spine. Case report.
  • Although histologically benign, they may exhibit invasive growth and destruction of the skull base.
  • [MeSH-major] Adenoma / etiology. Ear Neoplasms / pathology. Endolymphatic Sac. Spinal Cord Neoplasms / secondary

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  • (PMID = 16122027.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Zhi KQ, Deng PF, Ren WH, Zhang L, Li XQ, Wen YM: [A clinical retrospective study on modified parotidectomy in benign tumors of parotid gland]. Shanghai Kou Qiang Yi Xue; 2008 Jun;17(3):229-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A clinical retrospective study on modified parotidectomy in benign tumors of parotid gland].
  • Tumor size, blood loss, operating time, temporary facial paralysis, tumour recurrence were compared between the two groups.
  • RESULTS: There was no significant difference between the two groups in tumor size, temporary facial paralysis and tumor recurrence.
  • CONCLUSIONS: The modified parotidectomy is a function-preserving surgery for benign parotid tumours, which improves the cosmetics, the feeling around ear, reduces the duration of surgery, and the incidence rate of Frey's syndrome.
  • [MeSH-minor] Ear Auricle. Face. Facial Paralysis. Humans. Postoperative Complications. Retrospective Studies. Sweating, Gustatory

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  • (PMID = 18661059.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] China
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74. Jakobiec FA, Nguyen J, Bhat P, Fay A: Recurrent blue nevus of the corneoscleral limbus. Cornea; 2010 Aug;29(8):947-51
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  • The Ki-67 proliferation index was very low (0.05%), supporting a benign diagnosis.
  • CONCLUSIONS: Careful histopathological and immunohistochemical evaluation of recurrent, incompletely excised, blue nevi can determine if they remain benign.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Neoplasm Recurrence, Local. Nevus, Blue / surgery. Scleral Diseases / surgery
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Cryotherapy. Female. Humans. Sclerostomy

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  • (PMID = 20508501.001).
  • [ISSN] 1536-4798
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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75. Peterson NR, Summerlin DJ, Cordes SR: Multiple phosphaturic mesenchymal tumors associated with oncogenic osteomalacia: case report and review of the literature. Ear Nose Throat J; 2010 Jun;89(6):E11-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Oncogenic osteomalacia is a rare paraneoplastic syndrome that occurs secondary to tumor development in a variety of locations.
  • The most common causal tumor is phosphaturic mesenchymal tumor (PMT), a histologically benign lesion.
  • Despite resection of both tumors, the patient's signs and symptoms did not resolve, suggesting either incomplete tumor removal or the presence of another undetected tumor.
  • [MeSH-major] Bone Neoplasms / etiology. Hypophosphatemia, Familial / pathology. Mesenchymoma / etiology. Osteomalacia / complications. Tibia / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Neoplasms, Connective and Soft Tissue / pathology

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  • (PMID = 20556724.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 36
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76. Bogomilsky MR, Turusov DA, Kushel IuV, Zelikovich EI, Poliaev IuA: [Glomus tumors of the middle ear in children]. Vestn Otorinolaringol; 2007;(5):4-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Glomus tumors of the middle ear in children].
  • Glomus tumor (GT) is a rare tumor of the middle ear in children.
  • In spite of cytologically benign nature of this tumor, its course can be characterized as malignant because of GT infiltrative growth, destruction of the adjacent bone tissue, possible intracranial involvement.
  • At admission to hospital principal complaints of the children are poor hearing, discharge from the ear.
  • GT of the middle ear are detected with application of computed tomography which is able to show changes in the soft tissue and bone destruction, and angiography.
  • GT treatment planning depends on the examination data and can include radiotherapy, endovascular occlusion of the vessels carrying blood to the tumor, surgical treatment and combination of the methods.
  • [MeSH-major] Ear Neoplasms / epidemiology. Ear Neoplasms / pathology. Ear, Middle / pathology. Glomus Tumor / epidemiology. Glomus Tumor / pathology

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  • (PMID = 18163069.001).
  • [ISSN] 0042-4668
  • [Journal-full-title] Vestnik otorinolaringologii
  • [ISO-abbreviation] Vestn. Otorinolaringol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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77. Kiss S, Gragoudas ES, Dryja TP, Jakobiec FA: Response of choroidal leiomyoma to treatment with proton beam radiation. Retin Cases Brief Rep; 2010;4(2):168-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Uveal leiomyoma is a rare, benign smooth muscle neoplasm usually diagnosed only after local resection or enucleation.
  • The neoplasm was treated with a total of 70 cobalt gray equivalents of external proton beam radiation in 5 fractions over 7 days.
  • Biannual follow-up examinations over 3 years showed a funduscopically and ultrasonographically regressing tumor.
  • Microscopic and immunohistochemical examination of the mass revealed a choroidal neoplasm expressing smooth muscle antigens consistent with a uveal leiomyoma.

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  • (PMID = 25390394.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Sadetzki S, Chetrit A, Freedman L, Stovall M, Modan B, Novikov I: Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis. Radiat Res; 2005 Apr;163(4):424-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis.
  • Our aims were to assess the risk of radiation-induced malignant brain tumors and benign meningiomas after childhood exposure and to investigate the role of potential modifiers of that risk.
  • Survival analysis using Poisson regression was performed to estimate the excess relative and absolute risks (ERR, EAR) for brain tumors.
  • After a median follow-up of 40 years, an ERR/Gy of 4.63 and 1.98 (95% CI = 2.43-9.12 and 0.73-4.69) and an EAR/Gy per 10(4) PY of 0.48 and 0.31 (95% CI = 0.28-0.73 and 0.12-0.53) were observed for benign meningiomas and malignant brain tumors, respectively.
  • The estimated ERR/Gy for malignant brain tumors decreased with increasing age at irradiation from 3.56 to 0.47 (P = 0.037), while no trend with age was seen for benign meningiomas.
  • The ERR for both types of tumor remains elevated at 30-plus years after exposure.
  • [MeSH-major] Brain / radiation effects. Brain Neoplasms / epidemiology. Neoplasms, Radiation-Induced / epidemiology. Radiotherapy / statistics & numerical data. Risk Assessment / methods. Tinea Capitis / epidemiology. Tinea Capitis / radiotherapy


79. Saruya S, Nagamine H, Komiya T, Ito S, Iino Y, Kodera K, Imamura T: [Immunohistochemical and clinical features of patients with benign middle ear tumors]. Nihon Jibiinkoka Gakkai Kaiho; 2007 May;110(5):403-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Immunohistochemical and clinical features of patients with benign middle ear tumors].
  • The middle ear is a rare site for benign tumors.
  • We report six patients with benign middle ear tumors surgicaly removed: three with carcinoid, one with adenoma, and two with paraganglioma.
  • [MeSH-major] Adenoma / pathology. Carcinoid Tumor / pathology. Ear Neoplasms / pathology. Ear, Middle. Paraganglioma / pathology

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  • (PMID = 17564130.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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80. Wiatr M, Składzień J: [Benign tumors of the external and middle ear from data collected at the Otolaryngologyst Department of the Jagiellonian University in Cracow between 1992-2001]. Przegl Lek; 2007;64(12):1004-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign tumors of the external and middle ear from data collected at the Otolaryngologyst Department of the Jagiellonian University in Cracow between 1992-2001].
  • [Transliterated title] Nowotwory łagodne ucha zewnetrznego i środkowego w materiale Kliniki Otolaryngologii CM UJ w Krakowie w latach 1992-2001.
  • 26 patients with benign tumors of the external and middle ear were treated at the Otolaryngology Department of the Jagiellonian University in Cracow between 1992-2001.
  • Benign tumors of the external and middle ear are rare diseases, and it is usually easy to establish final diagnosis.
  • In our population the most common tumor was osteoma located in external ear canal.
  • [MeSH-major] Ear Neoplasms / surgery. Ear, External / surgery. Ear, Middle / surgery. Osteoma / surgery

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  • (PMID = 18595503.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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81. Fine HF, Ferrara DC, Ho IV, Takahashi B, Yannuzzi LA: Bilateral choroidal osteomas with polypoidal choroidal vasculopathy. Retin Cases Brief Rep; 2008;2(1):15-7
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  • BACKGROUND: A choroidal osteoma is a benign osseous tumor typically arising in the juxtapapillary or peripapillary area.
  • To our knowledge, this variant form of vasogenesis has not previously been described in association with this tumor.

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  • (PMID = 25389606.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Izadi F, Azizi MR, Ghanbari H, Kadivar M, Pousti B: Angiomyxoma of the larynx: case report of a rare tumor. Ear Nose Throat J; 2009 Jul;88(7):E11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomyxoma of the larynx: case report of a rare tumor.
  • Laryngeal spindle cell neoplasms are uncommon tumors, frequently misdiagnosed as reactive lesions or mesenchymal malignancies.
  • One of the rare mesenchymal tumors of the larynx is myxoid spindle cell tumor (angiomyxoma), a benign proliferative lesion.
  • Although benign, angiomyxomas have a propensity for local recurrence due to their tendency to infiltrate surrounding tissues.
  • They commonly appear encapsulated, but simple enucleation does not provide adequate treatment; excision should include a margin of normal tissue around the tumor.
  • The tumor in our case showed no histologic evidence of aggressive behavior, but because of the potential for local recurrence, close follow-up was warranted.
  • [MeSH-major] Laryngeal Neoplasms. Myxoma

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  • (PMID = 19623517.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Ferlito A, Devaney KO, Rinaldo A: Primary carcinoid tumor of the middle ear: a potentially metastasizing tumor. Acta Otolaryngol; 2006 Mar;126(3):228-31
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  • [Title] Primary carcinoid tumor of the middle ear: a potentially metastasizing tumor.
  • The concept of a carcinoid tumor in the gastrointestinal tract and lung is well established; less often, patients develop carcinoid tumors in the head and neck region.
  • One particularly uncommon site of origin of carcinoid tumors in the head and neck area is the middle ear.
  • Middle ear carcinoids have previously been approached as benign entities, lacking any capacity for metastasizing.
  • A critical review of the literature, however, disclosed a small number of cases in which middle ear carcinoid tumors have given rise to regional (cervical node) metastases.
  • This in turn suggests that, as is the case with pulmonary carcinoid tumors, middle ear carcinoids should be thought of as low-grade malignancies which, while relatively slow-growing, nevertheless possess a limited capacity for spreading to regional lymph nodes.
  • To date, distant metastases have not been associated with middle ear carcinoid tumors.
  • [MeSH-major] Carcinoid Tumor / secondary. Ear Neoplasms / pathology. Ear, Middle. Lymphatic Metastasis / pathology. Neoplasm Invasiveness / pathology
  • [MeSH-minor] Biopsy, Needle. Female. Humans. Immunohistochemistry. Male. Neoplasm Staging. Prognosis. Risk Assessment. Survival Rate. Treatment Outcome

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  • (PMID = 16618645.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Norway
  • [Number-of-references] 21
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84. Dharia A, Karmody CS, Rebeiz EE: Schwannoma of the nasal cavity. Ear Nose Throat J; 2007 Apr;86(4):230-1, 243
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  • Schwannomas are benign peripheral nerve sheath tumors that occur throughout the body.
  • [MeSH-major] Nasal Cavity / surgery. Neurilemmoma / surgery. Nose Neoplasms / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Nasal Obstruction / etiology. Nasal Obstruction / surgery. Nasal Septum / pathology. Nasal Septum / surgery. Otoscopy. S100 Proteins / analysis. Tomography, X-Ray Computed

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  • (PMID = 17500396.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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85. Butman JA, Linehan WM, Lonser RR: Neurologic manifestations of von Hippel-Lindau disease. JAMA; 2008 Sep 17;300(11):1334-42
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  • von Hippel-Lindau disease (VHL) is an autosomal-dominant neoplasia syndrome that is the result of a germline mutation of the VHL tumor suppressor gene on the short arm of chromosome 3.
  • Central nervous system lesions include hemangioblastomas (the most common tumor in VHL) and endolymphatic sac tumors (ELSTs).
  • Despite their benign pathology, hemangioblastomas and ELSTs are a frequent cause of morbidity and mortality in patients with VHL.

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  • (PMID = 18799446.001).
  • [ISSN] 1538-3598
  • [Journal-full-title] JAMA
  • [ISO-abbreviation] JAMA
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / BC / Z01 BC011038-01; United States / NCI NIH HHS / BC / Z01 BC011089-01; United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Clinical Conference; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Other-IDs] NLM/ NIHMS410216; NLM/ PMC3487164
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86. Han Z, Lin GJ, Chi FL, Wang SY, Huang JM, Liu HJ, Zhang LR: The relationship between the extracellular matrix and the angiogenesis and metastasis of laryngeal carcinoma. ORL J Otorhinolaryngol Relat Spec; 2008;70(6):352-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Thirty-three cases of benign and malignant laryngeal tumors were included.
  • RESULTS: The expression of ECM1 (p = 0.004) and HA (p = 0.036) was significantly different between benign and malignant tumors.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / secondary. Extracellular Matrix Proteins / metabolism. Laryngeal Neoplasms / pathology. Neovascularization, Pathologic / pathology
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Metastasis. Neoplasm Staging. Probability. Prognosis. Risk Assessment. Sampling Studies. Sensitivity and Specificity. Statistics, Nonparametric. Survival Analysis

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18984970.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ECM1 protein, human; 0 / Extracellular Matrix Proteins
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87. Zhao YS, Pang D, Wang F, Xue YW, Gao DN, Li H, Li K, Wang BY, Wang D, Li HY: Nipple aspirate fluid collection, related factors and relationship between carcinoembryonic antigen in nipple aspirate fluid and breast diseases in women in Harbin, PRC. Cancer Epidemiol Biomarkers Prev; 2009 Mar;18(3):732-8
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  • Multivariate logistic regression analysis results showed the following to be significantly associated with a greater ability to obtain nipple aspiration fluids: earlier age at menarche [odds ratio (OR), 2.61; 95% confidence interval (95% CI), 1.15-5.91], lactating>12 months (OR, 2.28; 95% CI, 1.44-3.60), wet-type ear wax (OR, 3.80; 95% CI, 2.39-6.02), and fatty diet (OR, 1.56; 95% CI, 1.02-2.39).
  • CEA levels in nipple aspiration fluids of cancerous breasts were significantly higher than those from breasts with benign disease and healthy controls (ORadj, 5.39; P<0.01).
  • [MeSH-major] Biomarkers, Tumor / analysis. Body Fluids / chemistry. Breast Diseases / diagnosis. Carcinoembryonic Antigen / analysis. Nipples

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  • (PMID = 19273481.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen
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88. Unsal Tuna EE, Ozbek C, Arda N, Ilkdogan E, Dere H, Ozdem C: Development of a Hodgkin disease tumor in the neck of a patient who previously had undergone complete excision of a hyaline-vascular Castleman disease neck mass. Ear Nose Throat J; 2010 Apr;89(4):E20-3
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  • [Title] Development of a Hodgkin disease tumor in the neck of a patient who previously had undergone complete excision of a hyaline-vascular Castleman disease neck mass.
  • A benign lymphoproliferative disorder, it may be seen as a self-limited unicentric process or as a fulminant multicentric disease with systemic symptoms.
  • [MeSH-major] Giant Lymph Node Hyperplasia / pathology. Hodgkin Disease / pathology. Lymph Node Excision. Otorhinolaryngologic Neoplasms / pathology

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  • (PMID = 20397132.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Lenarz M, Durisin M, Kamenetzki P, Becker H, Kreipe HH, Lenarz T: Cavernous hemangioma of the internal auditory canal. Eur Arch Otorhinolaryngol; 2007 May;264(5):569-71
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  • The presence of a small contrast-enhancing tumor in the internal auditory canal accompanied by severe sensorineural hearing loss and facial nerve palsy, should raise the suspicion of a hemangioma.
  • Early recognition and surgical intervention in these benign tumors may improve the chance of preserving the functional integrity of the facial nerve and provides better results after nerve reconstruction.
  • [MeSH-major] Ear, Inner / pathology. Facial Nerve / pathology. Hemangioma, Cavernous / pathology. Peripheral Nervous System Neoplasms / pathology. Vestibulocochlear Nerve / pathology

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  • (PMID = 17235534.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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91. Zhou L, Chen X, Huang W, Li K, Zhang X, Wang W: [Surgical management of minor salivary gland tumors]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Nov;21(21):963-5
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  • METHOD: Retrospective analysis of 54 cases with minor salivary gland tumor operated in our hospital from 1997 to 2004.
  • Among the remaining 38 patients, 2 patients with nasal cavity adenoid cystic carcinoma died of tumor recurrence 2 and 3 years after the surgery respectively, one patient with laryngeal myoepithelial carcinoma died of tumor recurrence 3 years after the surgery and one patient with paranasal sinus mucoepidermoid carcinoma died of recurrence 17 months after the surgery.
  • Two patients with paranasal sinus adenoid cystic carcinoma recurred after the primary surgery and were survived without tumor after salvage surgery.
  • The other patients survived with no tumor recurrence.
  • The treatment policy for benign tumors is simple tumor excision, while that for malignant tumors is surgery combined with pre- or post-operative radiation therapy.
  • Complete surgical resection of tumor masses and tumor free margin is essential for successful treatment of malignant minor salivary gland tumors.
  • [MeSH-major] Salivary Gland Neoplasms / surgery. Salivary Glands, Minor / surgery

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  • (PMID = 18309648.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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92. Chatziavramidis A, Grekou A, Thomaidis I, Sidiras T: Myoepithelioma of the larynx: a case report. Cases J; 2009;2:8085
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  • Myoepithelioma of the larynx is a very rare tumor with nonspecific local symptoms.
  • We present the second known case, focusing on the peculiarities of the differential diagnosis for this type of tumor that are crucial for the right histologic diagnosis and furthermore for the therapeutic outcome.We report a 37-year-old male presenting with hoarseness and dyspnea.
  • The indirect laryngoscopy revealed a gross glottic tumor from the right vocal cord who occupied the greater part of the glottis.
  • A modified vertical partial laryngectomy, under temporary tracheostomy, with muscle reconstruction for the deficit of the right vocal cord was applied for the removal of the tumor.
  • The benign character of the disease in conjunction with its slow progression could delay its detection and diagnosis, leading to a more destructive surgery.

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  • (PMID = 19918450.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769400
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93. Teppone M, Avakyan R: Extremely high-frequency therapy in oncology. J Altern Complement Med; 2010 Nov;16(11):1211-6
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  • The majority of the further studies demonstrated the high efficacy and safety of millimeter wave radiation in treating patients suffering from both benign and malignant tumors.
  • RESULTS: Developments led to treatment on skin melanoma, cancer of the ear-nose-throat, bowel and breast cancer, cancer of the uterus, lung, and stomach, solid tumors, as well as lymphoma.
  • (3) prevention of metastases, relapses, and dissemination of the tumor;.
  • [MeSH-major] Neoplasms / radiotherapy

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  • (PMID = 20973733.001).
  • [ISSN] 1557-7708
  • [Journal-full-title] Journal of alternative and complementary medicine (New York, N.Y.)
  • [ISO-abbreviation] J Altern Complement Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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94. Ethmoidal osteoid osteoma with orbital and intracranial extension - a case report. BMC Ear Nose Throat Disord; 2005 Mar 11;5:2
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  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton.
  • Radical excision of the tumor could thus be achieved through a craniofacial approach.
  • CONCLUSION: Although benign and rare, skull base osteoid osteoma can present with neurological deficit due to its mass effect and involvement of vital structures.

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  • (PMID = 15760476.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC555567
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95. Miller JP, Semaan M, Einstein D, Megerian CA, Maciunas RJ: Staged Gamma Knife radiosurgery after tailored surgical resection: a novel treatment paradigm for glomus jugulare tumors. Stereotact Funct Neurosurg; 2009;87(1):31-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECT: Although benign and slow growing, glomus jugulare tumors can be locally aggressive because of their proximity to lower cranial nerves and major vascular structures.
  • We report a novel treatment paradigm of tailored surgical resection followed by staged radiosurgery that allows for tissue diagnosis and immediate improvement of symptoms and tumor control without the morbidity of radical surgical resection.
  • METHODS: Five patients with glomus jugulare tumors and contraindications to extensive surgery each underwent an outpatient otologic procedure to resect the portion of the tumor in the middle ear and mastoid with no attempt to remove tumor in the jugular bulb.
  • Each patient returned 2-5 months later for Gamma Knife radiosurgery to the remainder of the tumor, which consisted of one 15-Gy dose prescribed to the 50% isodose curve.
  • Tumor volume was stable or reduced in all patients at most recent follow-up, and there were no immediate or delayed complications.
  • CONCLUSIONS: Staged outpatient microsurgical and radiosurgical therapy for glomus jugulare tumors in the symptomatic patient is safe and yields favorable results regarding tumor size, tinnitus, hearing and cranial nerve status.
  • [MeSH-major] Ear Neoplasms / surgery. Glomus Jugulare Tumor / surgery. Models, Anatomic. Radiosurgery / methods. Reoperation / methods. Skull Neoplasms / surgery

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  • (PMID = 19174618.001).
  • [ISSN] 1423-0372
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
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96. Boedeker M, Kayser G, Ridder GJ, Boedeker C: [Unusual tumor of the external ear]. Laryngorhinootologie; 2010 Nov;89(11):662-3
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  • [Title] [Unusual tumor of the external ear].
  • [Transliterated title] Ungewöhnlicher Tumor der Ohrmuschel1.
  • [MeSH-major] Ear Neoplasms / diagnosis. Ear, External. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biopsy. Diagnosis, Differential. Humans. Lymph Nodes / pathology. Male. Neck Dissection. Ultrasonography

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  • (PMID = 20556704.001).
  • [ISSN] 1438-8685
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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97. Jakobiec FA, Bhat P, Colby KA: Immunohistochemical studies of conjunctival nevi and melanomas. Arch Ophthalmol; 2010 Feb;128(2):174-83
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  • OBJECTIVE: To evaluate the role of immunohistochemical methods in the diagnosis of benign and malignant conjunctival melanocytic proliferations.
  • CONCLUSIONS: S-100 and MART-1 were not useful in separating benign from malignant lesions.
  • Immunostaining for HMB-45 and Ki-67 are valuable adjuncts to careful histopathologic evaluation in assessing benign and malignant conjunctival melanocytic tumors.
  • [MeSH-major] Biomarkers, Tumor / analysis. Conjunctival Neoplasms / diagnosis. Melanoma / diagnosis. Neoplasm Proteins / analysis. Nevus, Pigmented / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD45 / analysis. Antigens, Neoplasm / analysis. Child. Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Ki-67 Antigen / analysis. MART-1 Antigen. Male. Melanoma-Specific Antigens. Middle Aged. Retrospective Studies. S100 Proteins / analysis. Young Adult

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  • (PMID = 20142539.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 3.1.3.48 / Antigens, CD45; EC 3.1.3.48 / PTPRC protein, human
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98. Sumi T, Tsunoda A, Shirakura S, Kishimoto S: Mechanical obstruction of the eustachian tube by the benign tumor of the parapharyngeal space does not cause otitis media with effusion. Otol Neurotol; 2007 Dec;28(8):1072-5
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  • [Title] Mechanical obstruction of the eustachian tube by the benign tumor of the parapharyngeal space does not cause otitis media with effusion.
  • OBJECTIVE: We are reporting on eustachian tube and middle ear pathologic findings in patients with parapharyngeal tumors.
  • PATIENTS: Eleven cases of eustachian tube involvement as indicated by obstruction due to compression of the tumor were assessed in this study.
  • RESULTS: All of the tumors were diagnosed benign according to the histologic examination.
  • In 9 of the 11 patients, the pharyngeal opening of the eustachian tube narrowed or was blocked by the tumor.
  • None of the patients showed any response on the tumor side in the sonotubometry.
  • Therefore, gas exchange was prevented through the eustachian tube by the tumor; however, they also showed an intact tympanic membrane and normal hearing tests.
  • CONCLUSION: According to our data, if there is drainage of middle ear fluid through the eustachian tube and the exchange of gas in the middle ear is preserved, otitis media with effusion will not occur even in cases such as these.
  • [MeSH-major] Adenoma / complications. Eustachian Tube. Otitis Media with Effusion / etiology. Pharyngeal Neoplasms / complications
  • [MeSH-minor] Acoustic Impedance Tests. Adult. Audiometry, Pure-Tone. Ear, Middle / physiology. Female. Functional Laterality / physiology. Humans. Magnetic Resonance Imaging. Nasopharynx / pathology. Otoscopy. Tomography, X-Ray Computed. Tympanic Membrane / physiology

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  • (PMID = 18084819.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Uğuz MZ, Onal K, Demiray U, Ekinci N: Tumoral mass presenting in the nasomalar region arising from the lateral nasal wall: pleomorphic adenoma. Eur Arch Otorhinolaryngol; 2007 Nov;264(11):1377-9
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  • Pleomorphic adenoma is the most common benign salivary gland tumor.
  • Although the major salivary glands are the most common sites of its origin, it can also occur in the minor salivary glands of the oral cavity and rarely in the neck, ear, nasal cavity and larynx.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nasal Cavity / pathology. Nasal Septum / pathology. Nose Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Zygoma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • [Cites] Auris Nasus Larynx. 2004 Dec;31(4):439-42 [15571921.001]
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  • (PMID = 17549505.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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100. Mahalingam M, Kveaton JF, Bhawan J: Cutaneous neuroendocrine adenoma: an uncommon neoplasm. J Cutan Pathol; 2006 Apr;33(4):315-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous neuroendocrine adenoma: an uncommon neoplasm.
  • BACKGROUND: Cutaneous neuroendocrine neoplasms are typically malignant.
  • Benign cutaneous neuroendocrine tumors are uncommon.
  • RESULTS: Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation.
  • CONCLUSIONS: This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.
  • [MeSH-major] Ear Canal. Neuroendocrine Tumors / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Ear Neoplasms / diagnosis. Ear Neoplasms / surgery. Female. Humans. Immunohistochemistry

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  • (PMID = 16630184.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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