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1. Guney N, Sayilgan T, Derin D, Ozcan D: Primary carcinoid tumor arising in a mature cystic teratoma of the ovary: a case report. Eur J Gynaecol Oncol; 2009;30(2):223-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary carcinoid tumor arising in a mature cystic teratoma of the ovary: a case report.
  • OBJECTIVE: To present an extremely rare case of a primary carcinoid tumor arising in a mature cystic teratoma of the ovary.
  • Malignant transformation of mature cystic teratoma is an uncommon complication occuring in approximately 1-3% of patients with mature cystic teratoma.
  • Physical examination revealed a smooth, non-painful, 8-9 cm diameter mass in the right anterior pelvis which was diagnosed histologically as carcinoid tumor arising in a mature cystic teratoma.
  • CONCLUSION: This case adds to the rare reports in the literature of a carcinoid of low malignant potential occurring in a mature cystic teratoma.
  • The treatment for early-stage ovarian carcinoid tumors confined to one ovary is surgery alone and excellent outcomes can be expected in these cases.
  • [MeSH-major] Carcinoid Tumor / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology
  • [MeSH-minor] Female. Humans. Middle Aged. Teratoma


2. Bekiesińska-Figatowska M, Jurkiewicz E, Iwanowska B, Uliasz M, Romaniuk-Doroszewska A, Bragoszewska H, Ceran A, Olszewski A: Magnetic resonance imaging as a diagnostic tool in case of ovarian masses in girls and young women. Med Sci Monit; 2007 May;13 Suppl 1:116-20
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  • [Title] Magnetic resonance imaging as a diagnostic tool in case of ovarian masses in girls and young women.
  • MATERIAL/METHODS: Pelvic MRI was performed in 15 patients aged 9-19 years with suspected ovarian mass after they had had unclear gynecological and sonographic examinations.
  • RESULTS: In a group of 3 girls with acute abdominal pain, polycystic ovaries, ovarian hemorrhagic cyst, and fibroma of the ovary were diagnosed.
  • In a group of 11 patients with chronic abdominal pain, dermoid cysts of the ovaries were found in 7 cases, in one bilateral and accompanied by ectopic kidney.
  • In 2 patients, serous cysts were diagnosed.
  • In 2 cases an ovarian origin of the mass was excluded: multilocular cystic lesion in the presacral region and a hydatid mole were revealed.
  • A neoplastic ovarian mass was diagnosed in a girl with increasing circumference of the abdomen.
  • CONCLUSIONS: Magnetic resonance imaging, with its noninvasiveness, high spatial resolution, and tissue specificity, is a method of choice in the diagnosis or exclusion of ovarian pathology in children and adolescents.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Ovarian Diseases

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  • (PMID = 17507896.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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3. Ibraheim M, Ikomi A, Khan F: A pelvic retroperitoneal schwannoma mimicking an ovarian dermoid cyst in pregnancy. J Obstet Gynaecol; 2005 Aug;25(6):620-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A pelvic retroperitoneal schwannoma mimicking an ovarian dermoid cyst in pregnancy.
  • [MeSH-major] Dermoid Cyst / diagnosis. Neurilemmoma / diagnosis. Ovarian Neoplasms / diagnosis. Pelvic Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Pregnancy


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4. Argoitia X, Duga I, Labeyrie E, Toledo L, Couteau C, Querleu D: [Degeneration of dermoid cysts: a case study of malignant transformation]. Gynecol Obstet Fertil; 2007 Oct;35(10):1005-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Degeneration of dermoid cysts: a case study of malignant transformation].
  • [Transliterated title] Dégénérescence des kystes dermoïdes. A propos d'un cas de transformation maligne.
  • Malignant transformation of ovarian dermoid cyst (mature cystic teratoma) is rare and most often established in postmenopausal women after surgery by sample anatomopathological analysis.
  • The diagnosis of dermoid cyst was established upon ultrasonographic and tomodensitometric criteria.
  • In line with the literature, our study highlights the importance of the age of the patient, the size of dermoid cyst and its growth rate as well as squamous cell carcinoma (SCC) antigen serum level.
  • These date are collected in order to establish a correct diagnosis and provide an appropriate cure.
  • When a cyst is discovered these data must pathological event, mostly observed in menopaused women.
  • Certainty diagnosis is collected in order to establish a correct diagnosis and provide an appropriate cure.
  • [MeSH-major] Dermoid Cyst / pathology. Ovarian Neoplasms / pathology

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  • (PMID = 17916437.001).
  • [ISSN] 1297-9589
  • [Journal-full-title] Gynécologie, obstétrique & fertilité
  • [ISO-abbreviation] Gynecol Obstet Fertil
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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5. Ding DC, Chu TY, Hsu YH: Multimodality therapy of squamous cell carcinoma arising in mature cystic teratoma of ovary: a case report. Eur J Obstet Gynecol Reprod Biol; 2008 Apr;137(2):250-1
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  • [Title] Multimodality therapy of squamous cell carcinoma arising in mature cystic teratoma of ovary: a case report.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / therapy. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / therapy. Teratoma / diagnosis. Teratoma / therapy

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  • (PMID = 17208347.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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6. Hoffman JG, Strickland JL, Yin J: Virilizing ovarian dermoid cyst with leydig cells. J Pediatr Adolesc Gynecol; 2009 Jun;22(3):e39-40
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  • [Title] Virilizing ovarian dermoid cyst with leydig cells.
  • Overall, ovarian tumors causing virilization are exceedingly rare and mostly occur in post-menopausal women.
  • In fact, there are no reported cases of virilization from a testosterone-producing ovarian dermoid in the adolescent female age group.
  • The most frequent germ cell tumor derived from the ovaries is the benign cystic teratoma (dermoid) which accounts for 25% of all ovarian neoplasms.
  • Usually the tumors are asymptomatic, but they occasionally can cause severe pain if there is torsion or if sebaceous material perforates the cyst wall, leading to reactive peritonitis.
  • CASE: A 12-year-old female was found to have a large 3 5 x 19 x 12 cm ovarian mature cystic teratoma arising from her right ovary.
  • The dermoid was producing large amounts of testosterone from a nest of Leydig cells found pathologically in the mass.
  • CONCLUSION: Benign cystic teratomas can produce active hormones, albeit rarely.
  • This is a finding important to consider when ovarian cystectomy is performed for removal of a benign cystic teratoma.
  • [MeSH-major] Dermoid Cyst / pathology. Dermoid Cyst / secretion. Leydig Cells / secretion. Ovarian Neoplasms / pathology. Ovarian Neoplasms / secretion. Virilism / etiology

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  • (PMID = 19539195.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 3XMK78S47O / Testosterone
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7. Liberis V, Tsikouras P, Sivridis E, Dadidou M, Koutlaki N, Galazios G: Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. Clin Exp Obstet Gynecol; 2008;35(2):151-2
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  • [Title] Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report.
  • Mature cystic teratomas, often referred to as dermoid cysts, are the most common germ cell tumors of the ovary in women of reproductive age.
  • The gross pathologic appearance of a dermoid cysts is characteristic.
  • Hair follicles, skin glands, muscle, and other tissues lie within the cyst wall.
  • We present a case of a dermoid cyst ovarian tumor in a 24-your-old patient with a tooth lying on each wall.
  • The mass was laparoscopically removed by ovarian cystectomy.
  • [MeSH-major] Choristoma / pathology. Dermoid Cyst / pathology. Ovarian Neoplasms / pathology. Tooth

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  • (PMID = 18581775.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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8. Venizelos ID, Tatsiou ZA, Roussos D, Karagiannis V: A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. Onkologie; 2009 Jun;32(6):353-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma.
  • BACKGROUND: Mature cystic teratoma, also known as dermoid cyst, is the most common germ cell tumor of the ovary.
  • Malignant change in a component of a mature ovarian teratoma is rare, occurring in less than 2% of cases, with squamous cell carcinoma corresponding to 80% of such neoplasms.
  • Abdominal and pelvic ultrasound as well as computed tomography demonstrated a heterogenic tumor of the right ovary.
  • Histological examination of the tumor showed features of a well-differentiated sebaceous carcinoma arising within a mature cystic teratoma.
  • CONCLUSIONS: This is an extremely rare ovarian malignancy of which the clinical behavior and optimal management are not well established.
  • Differential diagnosis with other malignant neoplasms arising in mature cystic teratomas is exceedingly important for treatment and prognosis.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Neoplasms, Multiple Primary / diagnosis. Ovarian Cysts / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19521124.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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9. Tandon A, Gulleria K, Gupta S, Goel S, Bhargava SK, Vaid NB: Mature ovarian dermoid cyst invading the urinary bladder. Ultrasound Obstet Gynecol; 2010 Jun;35(6):751-3
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  • [Title] Mature ovarian dermoid cyst invading the urinary bladder.
  • Mature ovarian dermoid cysts are common lesions, accounting for up to 10-25% of all ovarian neoplasms.
  • Uncomplicated dermoid cysts are often asymptomatic and are relatively easy to diagnose on imaging and to treat.
  • The diagnosis of this condition has been through the use of cystoscopy or laparotomy in all cases reported so far.
  • We report a case of a 30-year-old patient with pyuria and dysuria, where ultrasound examination clearly demonstrated an ovarian dermoid cyst invading the urinary bladder.
  • A clear-cut imaging diagnosis helped to allow planning of surgery in advance and a mucosa-sparing partial bladder resection could be performed.
  • [MeSH-major] Dermoid Cyst / pathology. Ovarian Neoplasms / pathology. Urinary Bladder Neoplasms / pathology

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  • [Copyright] (c) 2009 ISUOG. Published by John Wiley & Sons, Ltd.
  • (PMID = 20069670.001).
  • [ISSN] 1469-0705
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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10. Al-Rayyan ES, Duqoum WJ, Sawalha MS, Nascimento MC, Pather S, Dalrymple CJ, Carter JR: Secondary malignancies in ovarian dermoid cyst. Saudi Med J; 2009 Apr;30(4):524-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secondary malignancies in ovarian dermoid cyst.
  • OBJECTIVE: To review our local experience with mature cystic ovarian teratoma, and describe our treatment modality regarding this uncommon condition.
  • RESULTS: Eleven cases of ovarian dermoid cyst with secondary malignancy were identified.
  • [MeSH-major] Cell Transformation, Neoplastic. Dermoid Cyst / pathology. Ovarian Neoplasms / pathology

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  • (PMID = 19370280.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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11. Savasi I, Lacy JA, Gerstle JT, Stephens D, Kives S, Allen L: Management of ovarian dermoid cysts in the pediatric and adolescent population. J Pediatr Adolesc Gynecol; 2009 Dec;22(6):360-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of ovarian dermoid cysts in the pediatric and adolescent population.
  • STUDY OBJECTIVE: To evaluate the surgical approach used in the management of ovarian dermoid cysts in the pediatric and adolescent population.
  • DESIGN: A descriptive retrospective chart review of all cases of ovarian dermoid cyst excision between January 2001 and January 2006.
  • PARTICIPANTS: Forty-one female children and adolescents who underwent operative management of an ovarian dermoid cyst.
  • MAIN OUTCOME MEASURES: Surgical approach (laparoscopy vs laparotomy), intraoperative cyst rupture, length of hospital stay, and postoperative complications.
  • All cysts were unilateral.
  • Cyst size was significantly larger in the laparotomy group compared to the laparoscopy group (mean diameter 14.4 cm vs 7.1 cm, respectively, P < .001).
  • A significantly higher rate of cyst rupture was experienced during laparoscopic cystectomy (100%), compared to excision via laparotomy (27.7%, P < .001).
  • There were no operative or postoperative complications related to cyst content spillage, regardless of the surgical approach.
  • CONCLUSION: Laparoscopic cystectomy is a safe and effective method of managing ovarian dermoid cysts in the pediatric and adolescent patient population.
  • [MeSH-major] Dermoid Cyst / surgery. Laparoscopy. Laparotomy. Ovarian Neoplasms / surgery

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  • (PMID = 19589709.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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12. Chang YT, Lin JY: Intraperitoneal rupture of mature cystic ovarian teratoma secondary to sit-ups. J Formos Med Assoc; 2009 Feb;108(2):173-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraperitoneal rupture of mature cystic ovarian teratoma secondary to sit-ups.
  • A case of general peritonitis caused by sudden perforation of a mature cystic ovarian teratoma is presented.

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  • (PMID = 19251554.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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13. Maurer T, Schnelzer A, Kremer M, May F, Hartung R: [Abdominal colic caused by mature cystic teratoma of the ovary]. Urologe A; 2007 Mar;46(3):284-6
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  • [Title] [Abdominal colic caused by mature cystic teratoma of the ovary].
  • Besides the typical urological reasons, differential diagnosis should include surgical, internal, and gynecological causes.
  • In particular, in cases of ambiguous calcifications on plain abdominal films - as shown in the presented case - a mature teratoma of the ovary should be taken into consideration.
  • [MeSH-major] Abdomen, Acute / diagnosis. Abdomen, Acute / etiology. Colic / diagnosis. Colic / etiology. Ovarian Neoplasms / complications. Ovarian Neoplasms / diagnosis. Teratoma / complications. Teratoma / diagnosis

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  • [Cites] J Am Assoc Gynecol Laparosc. 2003 Nov;10(4):489-90 [14738635.001]
  • [Cites] Eur J Gynaecol Oncol. 2005;26(4):446-8 [16122200.001]
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  • (PMID = 17068669.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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14. Adams H, Went P, Tolnay M, Sartorius G, Singer G: [Meningothelial meningioma in a mature cystic teratoma of the ovary]. Pathologe; 2007 Jul;28(4):278-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Meningothelial meningioma in a mature cystic teratoma of the ovary].
  • [Transliterated title] Meningotheliomatöses Meningeom in einem reifen zystischen Teratom des Ovars.
  • Mature teratomas belong to the group of germ cell tumors of the ovary.
  • They account for 27-44% of all ovarian neoplasms and up to 58% of all benign tumors of the ovary.
  • In mature as well as in immature teratomas, secondary tumors originating from the three embryonic tissue components may be found.
  • These tumors can show benign or malignant behavior.
  • We report the case of a meningothelial meningioma, found within a mature teratoma of a 32 year old female.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


15. McHugh JB, Fullen DR: Atypical compound nevus arising in mature cystic ovarian teratoma. Med Sci Monit; 2006 Apr;12(4):CS34-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical compound nevus arising in mature cystic ovarian teratoma.
  • BACKGROUND: Mature cystic ovarian teratoma (MCOT) is the most common primary ovarian tumor.
  • Histologically, the cystic neoplasm demonstrated epidermis with numerous pilosebaceous units and respiratory-type epithelium (endoderm) surrounded by adipose tissue and cartilage (mesoderm).
  • Moreover, melanomas may arise de novo or in association with a nevus.
  • As primary ovarian melanomas, like their skin counterpart, may arise from a precursor lesion, removal of a melanocytic nevus, such as this atypical nevus, could theoretically prevent melanoma transformation.
  • [MeSH-major] Neoplasms, Multiple Primary / diagnosis. Nevus, Pigmented / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 16572057.001).
  • [ISSN] 1234-1010
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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16. Kondo W, Bourdel N, Cotte B, Tran X, Botchorishvili R, Jardon K, Rabischong B, Pouly JL, Mage G, Canis M: Does prevention of intraperitoneal spillage when removing a dermoid cyst prevent granulomatous peritonitis? BJOG; 2010 Jul;117(8):1027-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does prevention of intraperitoneal spillage when removing a dermoid cyst prevent granulomatous peritonitis?
  • In this retrospective study of 314 patients undergoing surgery for ovarian dermoid cysts, conducted over a 20-year period, we evaluated the impact of the routine use of laparoscopic surgery without recourse to laparotomy to retrieve the specimen, using an endoscopic retrieval bag placed under the cyst to prevent intraperitoneal spillage of cyst contents, and subsequent postoperative granulomatous peritonitis.
  • Accidental cyst rupture was more frequent when a total laparoscopic approach was used (26/174 or 15% versus 39/140 or 28%; P = 0.005), but there were no cases of intraperitoneal spillage when an endoscopic bag was used.
  • Two cases of granulomatous peritonitis developed out of 26 women with intraperitoneal spillage of cyst contents (8%).
  • We conclude that the risk of granulomatous peritonitis can be minimised by undertaking laparoscopic removal of dermoid cysts with the routine intraoperative use of an endoscopic retrieval bag to prevent intraperitoneal spillage of cyst contents.
  • [MeSH-major] Dermoid Cyst / surgery. Laparoscopy / methods. Ovarian Neoplasms / surgery. Peritonitis / prevention & control. Postoperative Complications / prevention & control

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  • (PMID = 20465557.001).
  • [ISSN] 1471-0528
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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17. Luk J, Quaas A, Garner E: The superinfection of a dermoid cyst. Infect Dis Obstet Gynecol; 2007;2007:41473
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The superinfection of a dermoid cyst.
  • Mature cystic teratoma may be complicated by torsion, rupture, and malignant change, but is rarely complicated by infection.
  • Here we report the case of a patient who presented with a tubo-ovarian abscess following a dilation and curettage (D&C) procedure in the setting of an ovarian dermoid cyst.
  • [MeSH-major] Dermoid Cyst / microbiology. Ovarian Neoplasms / microbiology. Superinfection / complications. Superinfection / drug therapy

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  • [Cites] Obstet Gynecol. 1969 Jun;33(6):807-12 [5770554.001]
  • [Cites] Clin Obstet Gynecol. 1975 Mar;18(1):35-56 [804367.001]
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  • (PMID = 17641723.001).
  • [ISSN] 1098-0997
  • [Journal-full-title] Infectious diseases in obstetrics and gynecology
  • [ISO-abbreviation] Infect Dis Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Egypt
  • [Chemical-registry-number] N12000U13O / Doxycycline
  • [Other-IDs] NLM/ PMC1906865
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18. Amjad AI, Pal I: De novo primary squamous cell carcinoma of the ovary: a case of a rare malignancy with an aggressive clinical course. J Pak Med Assoc; 2008 May;58(5):272-4
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  • [Title] De novo primary squamous cell carcinoma of the ovary: a case of a rare malignancy with an aggressive clinical course.
  • Ovarian squamous cell carcinoma is a rare malignancy and the occurrence is attributable to malignant transformation of an existing ovarian dermoid cyst.
  • The de novo occurrence of squamous cell carcinoma of the ovary, in the absence of an antecedent ovarian dermoid, is extremely rare.
  • Histopathology demonstrated squamous cell carcinoma arising from the right ovary with no co-existing ovarian dermoid.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Ovarian Neoplasms / diagnosis. Ovariectomy / methods
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Colectomy / methods. Diagnosis, Differential. Disease Progression. Elective Surgical Procedures / methods. Female. Follow-Up Studies. Humans. Ileostomy / methods. Laparotomy. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 18655408.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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19. [TUBERCULOUS SALPINGITIS IN THE STAGE OF CALCIFICATION TO CASEOUS NECROSIS IN TEENAGE GIRL]. Tuberk Biolezni Legkih; 2010;(6):67-9
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  • Ovarian dermoid cysts and calcified lymph nodes are differentially diagnosed.
  • Diagnosis and treatment require surgical intervention (laparotomy, laparoscopy), sanitization of an infection focus, chemotherapy.

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  • (PMID = 27534060.001).
  • [ISSN] 2075-1230
  • [Journal-full-title] Tuberkulez i bolezni legkikh
  • [ISO-abbreviation] Tuberk Biolezni Legkih
  • [Language] rus
  • [Publication-type] Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Antitubercular Agents
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20. Leblebici C, Behzatoğlu K, Yildiz P, Koçyildiz Z, Bozkurt S: Extrarenal Wilms' tumor of the uterus with ovarian dermoid cyst. Eur J Obstet Gynecol Reprod Biol; 2009 May;144(1):94-5
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  • [Title] Extrarenal Wilms' tumor of the uterus with ovarian dermoid cyst.
  • [MeSH-major] Dermoid Cyst / diagnosis. Neoplasms, Multiple Primary / diagnosis. Ovarian Neoplasms / diagnosis. Uterine Neoplasms / diagnosis. Wilms Tumor / diagnosis


21. D'Angelo E, Dadmanesh F, Pecorelli S, Prat J: Squamous cell carcinoma of the ovary arising from a mucinous cystic tumor of endocervical (müllerian) type. Int J Gynecol Pathol; 2010 Nov;29(6):529-32
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  • [Title] Squamous cell carcinoma of the ovary arising from a mucinous cystic tumor of endocervical (müllerian) type.
  • Primary squamous cell carcinoma of the ovary is extremely rare.
  • We studied a 58-year-old woman in whom a keratinizing squamous cell carcinoma of the ovary had arisen from a mucinous cystic tumor of endocervical (müllerian) type.
  • The tumor was interpreted initially as a transitional cell carcinoma of the ovary with marked squamous differentiation, but there was no evidence of either transitional cell carcinoma or malignant Brenner tumor.
  • Furthermore, features of dermoid cyst (mature cystic teratoma), endometriosis, or adenosquamous carcinoma were not seen.
  • The mucinous columnar epithelial component was largely benign and only focally proliferative or borderline.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cystadenoma, Mucinous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology

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  • [CommentIn] Int J Gynecol Pathol. 2011 Jul;30(4):396-7 [21623198.001]
  • (PMID = 20881861.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K: Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data. Lancet Oncol; 2008 Dec;9(12):1173-80
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  • [Title] Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data.
  • Up to a quarter of ovarian masses originate from germ cells, and many of these are mature cystic teratomas.
  • The secondary development of malignancy is a rare but well-known phenomenon in patients with ovarian teratomas.
  • Squamous-cell carcinoma accounts for 80% of secondary malignant transformations of ovarian teratomas.
  • Squamous-cell carcinoma in mature cystic teratoma was mainly found in women aged more than 50 years, with high concentrations of squamous-cell-carcinoma antigen and cancer antigen CA125, and with ovarian tumours more than 100 mm in size.
  • We make proposals for investigation and treatment of this rare disorder.
  • [MeSH-major] Carcinoma, Squamous Cell. Ovarian Neoplasms. Teratoma

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  • [ErratumIn] Lancet Oncol. 2009 May;10(5):446
  • (PMID = 19038764.001).
  • [ISSN] 1474-5488
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen
  • [Number-of-references] 91
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23. Iwasa A, Oda Y, Kaneki E, Ohishi Y, Kurihara S, Yamada T, Hirakawa T, Wake N, Tsuneyoshi M: Squamous cell carcinoma arising in mature cystic teratoma of the ovary: an immunohistochemical analysis of its tumorigenesis. Histopathology; 2007 Jul;51(1):98-104
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  • [Title] Squamous cell carcinoma arising in mature cystic teratoma of the ovary: an immunohistochemical analysis of its tumorigenesis.
  • AIMS: Squamous cell carcinoma (SCC) is the most common form of malignant transformation in mature cystic teratoma (MCT) of the ovary.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Keratin-18 / metabolism. Ovarian Neoplasms / pathology. Teratoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Transformation, Neoplastic / metabolism. Epithelium / metabolism. Epithelium / pathology. Female. Gene Expression Regulation, Neoplastic. Humans. Keratin-10 / genetics. Keratin-10 / metabolism. Middle Aged. Ovary / metabolism. Ovary / pathology


24. Lataifeh I, Abdel-Hadi M, Morcos B, Sughayer M, Barahmeh S: Papillary thyroid carcinoma arising from mature cystic teratoma of the ovary. J Obstet Gynaecol; 2010;30(8):884-6
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  • [Title] Papillary thyroid carcinoma arising from mature cystic teratoma of the ovary.
  • [MeSH-major] Carcinoma, Papillary / pathology. Ovarian Neoplasms / pathology. Ovary / pathology. Teratoma / pathology. Thyroid Neoplasms / pathology

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  • (PMID = 21126146.001).
  • [ISSN] 1364-6893
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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25. Kavallaris A, Mytas S, Chalvatzas N, Nikolettos N, Diedrich K, Bohlmann MK, Hornemann A: Seven years' experience in laparoscopic dissection of intact ovarian dermoid cysts. Acta Obstet Gynecol Scand; 2010 Mar;89(3):390-2
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  • [Title] Seven years' experience in laparoscopic dissection of intact ovarian dermoid cysts.
  • A large case series on laparoscopic removal of dermoid cysts with a diameter between 3 and 12 cm, via an endobag, is reported (127 cysts in 121 premenopausal women).
  • The incidence of spillage and recurrence rate of laparoscopic ovarian dermoid cystectomy, the duration of the surgical procedure, the length of hospitalization, the incidence of recurrence and pregnancies was evaluated.
  • No signs or symptoms of peritonitis were observed regardless of cystic spillage or not.
  • Laparoscopic cystectomy of dermoid cysts in premenopausal women is safe and effective and appears to be a valuable alternative to laparotomy.
  • Controlled intraperitoneal spillage of cyst contents does not increase postoperative morbidity as long as an endobag is used and the peritoneal cavity is washed out thoroughly.
  • [MeSH-major] Dermoid Cyst / surgery. Ovarian Neoplasms / surgery

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  • (PMID = 19852568.001).
  • [ISSN] 1600-0412
  • [Journal-full-title] Acta obstetricia et gynecologica Scandinavica
  • [ISO-abbreviation] Acta Obstet Gynecol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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26. Min KJ, Jee BC, Lee HS, Kim YB: Intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary: a case report. Pathol Res Pract; 2006;202(7):531-5
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  • [Title] Intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary: a case report.
  • Gastrointestinal adenocarcinoma arising in mature cystic teratomas of the ovary is extremely rare.
  • We report a case of well-differentiated intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary in a 77-year-old woman, presenting as acute abdomen with ovarian torsion.
  • [MeSH-major] Adenocarcinoma / pathology. Intestinal Neoplasms / pathology. Neoplasms, Multiple Primary. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16713128.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Mucins; 68238-35-7 / Keratins
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27. Tsakiri SP, Turk CA, Lally KP, Garg K, Morris B: Atypical Meigs' syndrome in a neonate with ovarian torsion associated with an ovarian dermoid cyst. Pediatr Surg Int; 2005 May;21(5):407-9
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  • [Title] Atypical Meigs' syndrome in a neonate with ovarian torsion associated with an ovarian dermoid cyst.
  • We describe a female neonate with ovarian torsion, ovarian follicular and dermoid cysts, congenital ascites, pleural effusions, and respiratory distress.
  • This is the first report in a neonate of this syndrome in association with congenital ovarian disease.
  • [MeSH-major] Dermoid Cyst / congenital. Meigs Syndrome / complications. Ovarian Cysts / congenital. Ovarian Neoplasms / congenital

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  • [Cites] Obstet Gynecol. 1954 May;3(5):471-86 [13154792.001]
  • [Cites] J Pediatr Surg. 2001 May;36(5):693-9 [11329568.001]
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  • (PMID = 15739106.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


28. Brustmann H: Intestinal metastases in a squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case report. Ann Diagn Pathol; 2006 Dec;10(6):374-5
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  • [Title] Intestinal metastases in a squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case report.
  • Metastatic spread to the intestines by squamous cell carcinoma (SCC) arising in mature cystic teratoma (MCT) or dermoid cyst is a very rare event.
  • A case of a 40-year-old cachectic woman is presented with an MCT of the left ovary found at autopsy.
  • Focal mural thickening of the cyst wall harbored a moderately differentiated SCC with single cell keratinization.
  • In this unusual case, metastasizing SCC of the ovary arising in an MCT led to suppurative peritonitis and consequently to death of the patient.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Intestinal Neoplasms / secondary. Ovarian Neoplasms / pathology. Teratoma / secondary


29. Tate G, Tajiri T, Suzuki T, Mitsuya T: Mutations of the KIT gene and loss of heterozygosity of the PTEN region in a primary malignant melanoma arising from a mature cystic teratoma of the ovary. Cancer Genet Cytogenet; 2009 Apr 1;190(1):15-20
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  • [Title] Mutations of the KIT gene and loss of heterozygosity of the PTEN region in a primary malignant melanoma arising from a mature cystic teratoma of the ovary.
  • A frequent loss of heterozygosity (LOH) at 10q is found in melanoma; however, little is known about the role of PTEN in the pathogenesis of a primary malignant melanoma derived from ovarian mature cystic teratoma, which is an extremely rare melanoma.
  • This study examined the genetic alterations involved in the mitogen-activated protein kinase and phosphatidylinositol 3 kinase pathways in an ovarian malignant melanoma.
  • A LOH analysis revealed hemizygous deletion around and in the PTEN gene not only in the ovarian melanoma but also in a mature cystic teratoma.
  • Another case of ovarian mature cystic teratomas in the absence of melanoma also showed allelic loss of the PTEN region.
  • In the present study, D816H and K558E mutations of the KIT gene were revealed in the melanoma arising from a mature cystic teratoma, but not in a mature cystic teratoma.
  • These results indicate that LOH of the PTEN region is one of the molecular alterations of an ovarian mature cystic teratoma and a KIT mutation is an additional promotional event associated with the oncogenesis of a melanoma arising from an ovarian mature cystic teratoma.
  • [MeSH-major] Loss of Heterozygosity / physiology. Melanoma / genetics. Ovarian Neoplasms / genetics. PTEN Phosphohydrolase / genetics. Proto-Oncogene Proteins c-kit / genetics. Teratoma / genetics
  • [MeSH-minor] Aged. DNA Mutational Analysis. Dermoid Cyst / genetics. Dermoid Cyst / pathology. Female. Humans. Mutation / physiology. Neoplasms, Multiple Primary / genetics. Neoplasms, Multiple Primary / pathology


30. Walid MS, Boddy MG: Bilateral dermoid cysts of the ovary in a pregnant woman: case report and review of the literature. Arch Gynecol Obstet; 2009 Feb;279(2):105-8
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  • [Title] Bilateral dermoid cysts of the ovary in a pregnant woman: case report and review of the literature.
  • OBJECTIVE: Most nonphysiological ovarian masses discovered during pregnancy are benign dermoid cysts.
  • The association of dermoid cysts with pregnancy has been increasingly reported since 1918.
  • RESULT: The bilateral dermoid cysts were surgically treated in the second trimester.
  • CONCLUSION: Most references state that it is more feasible to treat bilateral dermoid cysts of the ovaries discovered during pregnancy if they grow beyond 6 cm in diameter.
  • [MeSH-major] Dermoid Cyst / diagnosis. Ovarian Cysts / diagnosis. Pregnancy Complications, Neoplastic / diagnosis

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  • (PMID = 18509663.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 39
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31. Chappell NP, Irisari LG: Degenerating uterine myomas mimic ovarian dermoid cysts in a postmenopausal woman. J Minim Invasive Gynecol; 2010 Nov-Dec;17(6):684-5
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  • [Title] Degenerating uterine myomas mimic ovarian dermoid cysts in a postmenopausal woman.
  • [MeSH-major] Dermoid Cyst / diagnosis. Leiomyomatosis / diagnosis. Ovarian Neoplasms / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Postmenopause

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  • (PMID = 20955979.001).
  • [ISSN] 1553-4669
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Cabibi D, Martorana A, Cappello F, Barresi E, Di Gangi C, Rodolico V: Carcinosarcoma of monoclonal origin arising in a dermoid cyst of ovary: a case report. BMC Cancer; 2006;6:47
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  • [Title] Carcinosarcoma of monoclonal origin arising in a dermoid cyst of ovary: a case report.
  • BACKGROUND: Transformation of a cystic benign teratoma of the ovary into a "carcinosarcoma" has very rarely been reported and its histogenetic origin is still debated.
  • CASE PRESENTATION: A case of carcinosarcoma arising from a dermoid cyst is reported.
  • The tumor showed cystic areas delimited by normal squamous epithelium, with transitional areas through dysplastic epithelium to "in situ" and infiltrating squamous cell carcinoma (SCC).
  • CONCLUSION: To the best of our knowledge, this is the first case of carcinosarcoma arising from a dermoid cyst in which a histogenetic origin from totipotent stem cells, located in the basal squamous layer, is supported by immunohistochemical findings.
  • [MeSH-major] Carcinosarcoma / pathology. Cell Transformation, Neoplastic / pathology. Dermoid Cyst / pathology. Ovarian Neoplasms / pathology

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  • (PMID = 16509974.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1420311
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33. Cebesoy FB, Baskonus I, Mete A, Kutlar I, Aybasti N: Benign ovarian dermoid cyst complicated with rectal fistula formation: an unusual case. Arch Gynecol Obstet; 2009 Feb;279(2):179-81
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  • [Title] Benign ovarian dermoid cyst complicated with rectal fistula formation: an unusual case.
  • BACKGROUND: Fistulation in benign cystic teratomas has not been commonly reported in the literature.
  • We present a case of a benign ovarian dermoid cyst complicated with a recto-ovarian fistula.
  • Gynecological examination and ultrasonography revealed a 10-cm heterogeneous cystic mass in the left ovary.
  • Abdominopelvic CT scan revealed a left ovarian mass (10 x 9 cm) thought to be a dermoid cyst, which was seen to penetrate the proximal part of the rectum.
  • The pathological evaluation suggested benign ovarian dermoid tumor penetrating the rectum wall.
  • CONCLUSION: Fistula formation by a dermoid ovarian cyst is not always related to malignant transformation of the cyst.
  • In addition to factors such as torsion, infection, trauma, and chronic pressure during labor, spontaneous rupture of the dermoid cyst resulting in leakage of fluid could be the cause of fistula formation.
  • [MeSH-major] Fistula / diagnosis. Ovarian Cysts / diagnosis. Ovarian Diseases / diagnosis. Rectal Fistula / diagnosis

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  • (PMID = 18449552.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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34. Ulbright TM: Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol; 2005 Feb;18 Suppl 2:S61-79
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  • [Title] Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
  • The most dramatic examples of the latter are the frequency of dermoid cyst in the ovary compared to the testis and the reverse pertaining to embryonal carcinoma.
  • Within the teratoma group, there is strong evidence that ovarian and prepubertal testicular teratomas are derived from benign germ cells, a pathogenesis that likely applies also to the rare dermoid cysts and uncommon epidermoid cysts of the testis.
  • As expected, given the foregoing, teratomas in boys are clinically benign, whereas in postpubertal males they are malignant, independent of their degree of immaturity.
  • On the other hand, immaturity is an important finding in ovarian teratomas, irrespective of age, although its significance in children has recently been challenged.
  • It is usually recognized on the basis of embryonic-appearing neuroepithelium, which shows mitotic activity and apoptosis in contrast to differentiated neuroepithelial tissues, which may occur in mature ovarian teratomas.
  • Fetal-type tissues alone are not sufficient for a diagnosis of immature teratoma.
  • Further differences between the teratomatous tumors in the two gonads are the relative frequency of monodermal teratomas in the ovary in contrast to the testis, where only one subset, carcinoids, is seen with any frequency.
  • When uncommon somatic-type malignancies (usually squamous cell carcinoma) occur in mature cystic teratomas of the ovary, this is a de novo form of malignant transformation; similar tumors in the testis, a very rare event, represent overgrowth of teratomatous elements that originated from malignant, nonteratomatous germ cell tumors and, therefore, had previously undergone malignant transformation.
  • Cytoplasmic membrane immunoreactivity for placental alkaline phosphatase and CD117, with usual negativity for AE1/AE3 cytokeratins, is helpful in the diagnosis of germinoma.
  • Yolk sac tumor continues to be confused occasionally with clear cell carcinoma of the ovary.
  • Glandular ('endometrioid-like') yolk sac tumors mimic endometrioid carcinomas; predominant or pure hepatoid yolk sac tumors cause concern for metastatic hepatocellular carcinoma or, in the ovary, primary hepatoid carcinoma, and solid patterns, especially in limited samplings, may be misinterpreted as germinoma.
  • Choriocarcinoma is rare in both gonads, and those in the ovary must be distinguished from metastatic tumors of placental origin.
  • Mixed germ cell tumors (which may show almost any combination of components) are common in the testis but rare in the ovary.
  • These tumors, which are constituted by innumerable embryoid bodies, almost always contain teratomatous glands in minor amounts, and one way of viewing the polyembryoma is to consider it the most immature form of teratoma.
  • [MeSH-major] Neoplasms, Germ Cell and Embryonal / pathology. Ovarian Neoplasms / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Antigens, CD30 / analysis. Diagnosis, Differential. Female. Germinoma / metabolism. Germinoma / pathology. Humans. Immunohistochemistry. Keratin-7. Keratins / analysis. Male. Organic Cation Transport Proteins / analysis. Proto-Oncogene Proteins c-kit / analysis. Teratoma / metabolism. Teratoma / pathology

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  • (PMID = 15761467.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / KRT7 protein, human; 0 / Keratin-7; 0 / Organic Cation Transport Proteins; 0 / solute carrier family 22 (organic cation transporter), member 3; 68238-35-7 / Keratins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Number-of-references] 132
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35. Ishikawa M, Nakayama K, Yeasmin S, Katagiri A, Iida K, Nakayama N, Miyazaki K: [Paclitaxel + carboplatin (TC)-resistant stage Ic squamous cell carcinomas arising in mature cystic teratomas of the ovary]. Gan To Kagaku Ryoho; 2010 Apr;37(4):747-52
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  • [Title] [Paclitaxel + carboplatin (TC)-resistant stage Ic squamous cell carcinomas arising in mature cystic teratomas of the ovary].
  • Malignant transformation of an ovarian mature cystic teratoma is very rare; it arises in about 1-2% of all dermoid cysts.
  • In Case 1, a 78-year-old woman was diagnosed with squamous cell carcinoma arising from a mature cystic teratoma of the ovary after undergoing right salpingo-oophorectomy (RSO).
  • The results of TAE, however, showed that it may be an effective second-line therapy for recurrent squamous cell carcinoma arising from a mature cystic teratoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / therapeutic use. Carcinoma, Squamous Cell / drug therapy. Drug Resistance, Multiple. Drug Resistance, Neoplasm. Ovarian Neoplasms / drug therapy. Paclitaxel / therapeutic use

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  • (PMID = 20414041.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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36. Kaminski P, Gajewska M, Wielgos M, Szymusik I: Laparoscopic management of dermoid cysts in patients of reproductive age. Neuro Endocrinol Lett; 2006 Dec;27(6):818-21
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  • [Title] Laparoscopic management of dermoid cysts in patients of reproductive age.
  • OBJECTIVE: Ovarian dermoid cysts are one of the most common germ cell tumors in women.
  • The aim of the study was to analyze the use of laparoscopy in dermoid cysts treatment in women of reproductive age.
  • MATERIAL AND METHODS: The studied material consisted of 95 patients, aged 17-49, operated on because of dermoid cyst suspicion at the 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, in the years 1996-2005.
  • All the patients had pre-operative CA-125 antigen evaluation and transvaginal sonography with Doppler assessment of the ovarian pathology.
  • Out of 95 studied cases, 93 (97.9%) had the cyst removed during laparoscopy, mostly elective.
  • Dermoid cyst enucleation was the most commonly applied procedure, while oophorectomy was the least frequent.
  • The whole gonad was removed in 33 patients (34.7%), generally because of the total loss of functional ovarian tissue surrounding the cyst (28 women; 29.5%).
  • All the extracted material was submitted for a histopathological examination--the diagnosis of mature ovarian cystic teratoma was confirmed in 100% of cases.
  • In 85 (89.5%) operated patients an ovarian tumor was earlier described as a dermoid cyst.
  • CONCLUSIONS: Laparoscopic treatment of ovarian dermoid cysts is a safe method, offering many advantages in comparison to classical surgery.
  • [MeSH-major] Dermoid Cyst / surgery. Laparoscopy / methods. Ovarian Neoplasms / surgery

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  • (PMID = 17187015.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / CA-125 Antigen
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37. Zheng HF, Jiang BY, Shen DH: [Signet ring cell carcinoma arising from mature cystic teratoma of the ovary]. Zhonghua Bing Li Xue Za Zhi; 2005 Sep;34(9):610-1
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  • [Title] [Signet ring cell carcinoma arising from mature cystic teratoma of the ovary].
  • [MeSH-major] Carcinoma, Signet Ring Cell / pathology. Cell Transformation, Neoplastic / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16468323.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Carcinoembryonic Antigen; 0 / Keratin-20; Q20Q21Q62J / Cisplatin
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38. Büyükka Bay S, Corapcioglu F, Kavurt S, Müezzinoğlu B, Anik Y, Tugay M: Oligodendroglioma arising in a mature cystic ovarian teratoma in a child. Pediatr Hematol Oncol; 2010 Nov;27(8):636-40
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  • [Title] Oligodendroglioma arising in a mature cystic ovarian teratoma in a child.
  • In childhood mature cystic teratomas are the most common type of ovarian germ cell tumors.
  • Tumors of neuroepithelial origin are extremely rare in mature teratomas.
  • To the authors' knowledge, this is the first case report oligodendroglioma arising in a mature cystic ovarian teratoma in children.
  • An ultrasound examination showed a monolateral multicystic, calcific ovarian mass, measuring approximately 6 x 5 cm, arising in the left over and adnexia, suggesting a teratoma.
  • On histopatological examination, various samples from cystic areas had mature tissues from all 3 germ cell layers, including skin, bone, bronchial structures, and cerebellum.
  • Based on the typical morphological features, the cased was diagnosed as mature cystic teratoma with low-grade oligodendroglioma.
  • To the authors' knowledge, there are a few reports in the literature of an oligodendroglioma arising in an ovarian teratoma in adults and this presented patient is the first case in childhood.
  • [MeSH-major] Oligodendroglioma / diagnosis. Ovarian Cysts / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis


39. Nitinavakarn B, Prasertjaroensook V, Kularkaew C: Spontaneous rupture of an ovarian dermoid cyst associated with intra-abdominal chemical peritonitis: characteristic CT findings and literature review. J Med Assoc Thai; 2006 Apr;89(4):513-7
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  • [Title] Spontaneous rupture of an ovarian dermoid cyst associated with intra-abdominal chemical peritonitis: characteristic CT findings and literature review.
  • A case of ruptured ovarian dermoid is documented including the characteristic CT findings of chemical peritonitis based on the fatty peritoneal fluid content similar to that found in fatty dermoids.
  • [MeSH-major] Dermoid Cyst / diagnosis. Ovarian Neoplasms / diagnosis. Peritonitis / diagnosis. Rupture, Spontaneous / diagnosis

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  • (PMID = 16696398.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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40. Mandal S, Kawatra V, Khurana N: Mucinous cystadenocarcinoma arising in mature cystic teratoma ovary and associated pseudomyxoma peritonei: report of a case. Arch Gynecol Obstet; 2008 Sep;278(3):265-7
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  • [Title] Mucinous cystadenocarcinoma arising in mature cystic teratoma ovary and associated pseudomyxoma peritonei: report of a case.
  • Pseudomyxoma peritonei (PMP) is most commonly associated with intra-abdominal spread of an appendiceal mucinous neoplasm and very rarely seen in cases of primary ovarian tumours.
  • Mucinous adenocarcinoma arising in a mature cystic teratoma giving rise to PMP is even rarer.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology. Teratoma / pathology

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  • (PMID = 18293005.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CA-125 Antigen
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41. Shariat-Torbaghan S, Emami-Aleagha M, Sedighi S, Azadbakht F, Keshvari A, Hajarizadeh B, Rosai J: Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report. Arch Iran Med; 2009 Mar;12(2):186-9
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  • [Title] Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report.
  • Malignant transformation in a mature cystic teratoma of the ovary is rare.
  • In the present report, we describe a case of advanced-stage squamous cell carcinoma arising in a mature cystic teratoma.
  • A postmenopausal 63-year-old woman with squamous cell carcinoma arising in a mature cystic teratoma is presented.
  • Histopatholog was compatible with squamous cell carcinoma arising in a mature cystic teratoma.
  • [MeSH-major] Carcinoma, Squamous Cell / ultrasonography. Neoplasms, Multiple Primary / ultrasonography. Ovarian Neoplasms / ultrasonography. Teratoma / ultrasonography

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  • (PMID = 19249893.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 12001-76-2 / Vitamin B Complex; Q20Q21Q62J / Cisplatin; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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42. Sinha R, Sundaram M, Lakhotia S: Multiple intraabdominal parasitic cystic teratomas. J Minim Invasive Gynecol; 2009 Nov-Dec;16(6):789-91
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  • [Title] Multiple intraabdominal parasitic cystic teratomas.
  • We report an interesting case of multiple intraabdominal dermoids in a patient who had undergone an excision of ovarian dermoid cyst earlier and presented with recurrence of symptoms.
  • She had masses all over the abdominal wall, omentum, and pouch of Douglas and a dermoid cyst in the ovary as well.
  • It is generally believed that autoamputation and reimplantation of an ovarian dermoid cyst is the most common cause of omental teratomas.
  • Both ultrasonography with color-flow Doppler ultrasonography and computed tomography are helpful in the diagnosis of dermoid tumors, but the correct diagnosis of omental localization is extremely difficult.
  • [MeSH-major] Abdominal Neoplasms / surgery. Dermoid Cyst / surgery. Douglas' Pouch / surgery. Laparoscopy / methods. Omentum / surgery

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  • (PMID = 19896613.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Hwang JH, So KA, Modi G, Lee JK, Lee NW, Lee KW, Kim I: Borderline-like mucinous tumor arising in mature cystic teratoma of the ovary associated with pseudomyxoma peritonei. Int J Gynecol Pathol; 2009 Jul;28(4):376-80
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  • [Title] Borderline-like mucinous tumor arising in mature cystic teratoma of the ovary associated with pseudomyxoma peritonei.
  • However, a mucinous neoplasm arising in a mature cystic teratoma is rarely responsible for PMP.
  • We herein report 2 cases of PMP associated with borderline mucinous tumors arising in mature cystic teratoma.
  • Both ovarian borderline mucinous tumors were morphologically and immunohistochemically similar to the secondary tumors from appendiceal origin, and PMP was histologically similar to peritoneal adenomucinosis.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology. Teratoma / pathology

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  • (PMID = 19483624.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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44. Kusaka M, Mikuni M: Ectopic ovary: a case of autoamputated ovary with mature cystic teratoma into the cul-de-sac. J Obstet Gynaecol Res; 2007 Jun;33(3):368-70
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  • [Title] Ectopic ovary: a case of autoamputated ovary with mature cystic teratoma into the cul-de-sac.
  • An ovary with a mature cystic teratoma which was autoamputated into the cul-de-sac and confirmed by laparoscopy is described.
  • Magnetic resonance imaging revealed a left ovarian mass of 5 cm in diameter.
  • The mass was identified in the cul-de-sac partly enveloped in the omentum without any ligamentous or direct connection with the pelvic organs.
  • There was no left ovary in its proper anatomical location.
  • Histopathologic study revealed a mature cystic teratoma with viable ovarian tissue.
  • These findings suggested autoamputation of the ovary either by inflammation or torsion, which is one of the mechanisms for the formation of an ectopic ovary.
  • [MeSH-major] Douglas' Pouch / pathology. Ovarian Neoplasms / pathology. Ovary / pathology. Teratoma / pathology

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  • (PMID = 17578369.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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45. Sakuma M, Otsuki T, Yoshinaga K, Utsunomiya H, Nagase S, Takano T, Niikura H, Ito K, Otomo K, Tase T, Watanabe Y, Yaegashi N: Malignant transformation arising from mature cystic teratoma of the ovary: a retrospective study of 20 cases. Int J Gynecol Cancer; 2010 Jul;20(5):766-71
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  • [Title] Malignant transformation arising from mature cystic teratoma of the ovary: a retrospective study of 20 cases.
  • OBJECTIVES: Mature cystic teratoma (MCT) of the ovary rarely undergoes malignant transformation (MT).
  • Malignant transformation carries a significantly worse prognosis than epithelial ovarian cancer, regardless of whether postoperative chemotherapy or radiotherapy is applied.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 20973266.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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46. Budiman HD, Burges A, Rühl IM, Friese K, Hasbargen U: Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy. Arch Gynecol Obstet; 2010 Mar;281(3):535-7
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  • [Title] Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy.
  • BACKGROUND: A rare complication of mature cystic teratoma of the ovary is malignant transformation, mostly being squamous cell carcinoma (SCC).
  • CASE: A 41-year-old pregnant woman presented with a right ovarian tumour.
  • [MeSH-major] Dermoid Cyst / pathology. Neoplasms, Squamous Cell / pathology. Ovarian Cysts / pathology. Ovarian Neoplasms / pathology. Pregnancy Complications, Neoplastic / pathology


47. Veras E, Deavers MT, Silva EG, Malpica A: Ovarian nonsmall cell neuroendocrine carcinoma: a clinicopathologic and immunohistochemical study of 11 cases. Am J Surg Pathol; 2007 May;31(5):774-82
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  • [Title] Ovarian nonsmall cell neuroendocrine carcinoma: a clinicopathologic and immunohistochemical study of 11 cases.
  • Nonsmall cell neuroendocrine carcinoma (NSCNEC) of the ovary is a rare and aggressive tumor commonly associated with other surface epithelial and germ cell neoplasms.
  • Tumors were mostly unilateral, cystic, or solid/cystic and ranged in size from 5 to 26 cm (mean 16.2).
  • In 2 cases, the tumor was associated with a mature cystic teratoma; one of them also containing an invasive moderately differentiated adenocarcinoma.
  • A single case was associated with a benign ovarian cyst.
  • The latter case had a dermoid cyst in the contralateral ovary.
  • NSCNEC represented anywhere from 10% to 90% of the ovarian tumor.
  • In summary, ovarian NSCNEC is an aggressive tumor with a tendency to present at advanced stage and cause death within a mean of 17 months after diagnosis; however, some patients, particularly those with stage I disease and/or those who have received platinum-based therapy, may have a more favorable prognosis.
  • [MeSH-major] Biomarkers, Tumor. Carcinoma, Neuroendocrine / pathology. Immunoenzyme Techniques. Ovarian Neoplasms / pathology

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  • (PMID = 17460463.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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48. Upadhye V, Gujral S, Maheshwari A, Wuntkal R, Gupta S, Tongaonkar H: Benign cystic teratoma of ovary perforating into small intestine with co-existent typhoid fever. Indian J Gastroenterol; 2005 Sep-Oct;24(5):216-7
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  • [Title] Benign cystic teratoma of ovary perforating into small intestine with co-existent typhoid fever.
  • Intra-peritoneal rupture or perforation into adjacent abdominal viscera is a rare complication of benign cystic teratoma (dermoid cyst) of the ovary.
  • We report a 48-year-old woman in whom an ovarian dermoid cyst perforated into a loop of the small bowel.
  • [MeSH-major] Intestinal Perforation / etiology. Ovarian Neoplasms / complications. Teratoma / complications. Typhoid Fever / complications

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  • (PMID = 16361767.001).
  • [ISSN] 0254-8860
  • [Journal-full-title] Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
  • [ISO-abbreviation] Indian J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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49. Las Heras F, Pritzker KP, Colgan TJ: Chordoma arising in a mature cystic teratoma of the ovary: a case report. Pathol Res Pract; 2007;203(6):467-71
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  • [Title] Chordoma arising in a mature cystic teratoma of the ovary: a case report.
  • Mature cystic teratoma of the ovary (MCTO) is the most common type of ovarian teratoma and also the most frequent tumor originating from germ cells.
  • Squamous cell carcinoma is the most common malignancy arising in these otherwise benign tumors.
  • [MeSH-major] Cell Differentiation. Cell Transformation, Neoplastic / pathology. Chordoma / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Adult. Chromosomes, Human, Pair 7. Chromosomes, Human, X. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Keratins / analysis. Ki-67 Antigen / analysis. Mosaicism. Mucin-1 / analysis. S100 Proteins / analysis. Tumor Suppressor Protein p53 / analysis. Vimentin / analysis

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  • (PMID = 17418959.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / S100 Proteins; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 0 / Vimentin; 68238-35-7 / Keratins
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50. Peitsidou A, Peitsidis P, Goumalatsos N, Papaspyrou R, Mitropoulou G, Georgoulias N: Diagnosis of an autoamputated ovary with dermoid cyst during a Cesarean section. Fertil Steril; 2009 Apr;91(4):1294.e9-12
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  • [Title] Diagnosis of an autoamputated ovary with dermoid cyst during a Cesarean section.
  • OBJECTIVE: To report an extremely rare case of an autoamputated ovary with a dermoid cyst diagnosed during a Cesarean section and review the literature.
  • PATIENT(S): A 33-year-old pregnant woman submitted to Cesarean section and was incidentally diagnosed with absence of the right ovary, implanted in the cul-de-sac.
  • INTERVENTION(S): Cesarean section and extraction of a pedunculated tumor formation from the cul-de-sac, adhesiolysis.
  • MAIN OUTCOME MEASURE(S): Histologic analysis of the extracted morphoma confirmed the diagnosis of a dermoid cyst with coexistence of residual ovarian tissue.
  • CONCLUSION(S): Ovarian autoamputation is an extremely rare phenomenon that has uncertain etiology; it may develop after ovarian torsion or torsion of a dermoid cyst.
  • [MeSH-major] Cesarean Section. Choristoma / diagnosis. Dermoid Cyst / diagnosis. Genital Diseases, Female / diagnosis. Ovarian Neoplasms / diagnosis. Ovary
  • [MeSH-minor] Adult. Amputation, Traumatic / diagnosis. Amputation, Traumatic / etiology. Female. Humans. Incidental Findings. Pregnancy. Torsion Abnormality / complications. Torsion Abnormality / diagnosis. Torsion Abnormality / surgery

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  • (PMID = 19176224.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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51. Sheikh MA, Akhtar J, Batool T, Naqvi R, Taqvi R, Jalil S, Soomro A, Ahmed S, Mirza F: A study of ovarian lesions in pre-menarche girls. J Coll Physicians Surg Pak; 2007 Mar;17(3):162-5
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  • [Title] A study of ovarian lesions in pre-menarche girls.
  • OBJECTIVE: To analyze various clinical presentations and the surgical management of ovarian pathologies in pre-menarche girls.
  • PATIENTS AND METHODS: Case records of all the pre-menarche girls child having an ovarian pathology and managed during the study period were reviewed.
  • Age of the patients, presenting symptoms, investigations performed, surgical approaches, operative findings and final histological diagnosis were noted.
  • Ovarian lesions were classified according to WHO criteria.System proposed by the Children's Cancer Group and the Paediatric Oncology Group was used for staging of tumors.
  • RESULTS: There were 18 patients with ovarian lesions.
  • Right ovary was involved in 12 (55%) cases and left in 6 (45%).
  • Six patients had non-tumorous cysts, 3 had benign tumors and 9 were with malignant lesions.
  • Of the non-tumorous cysts, 3 patients had simple follicular cysts and 2 were hemorrhagic cysts.
  • There were 2 patients with benign teratoma and one with dermoid cyst.
  • Four patients had malignant teratoma, 4 dysgerminoma and one yolk sac tumor.
  • CONCLUSION: Ovarian tumors are rare in paediatric age group especially in pre-menarche girls.
  • Benign (tumorous and non-tumorous) and malignant lesions occurred with equal frequency in pre-menarche girls in this study.
  • [MeSH-major] Ovarian Diseases

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  • (PMID = 17374303.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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52. da Silva BB, dos Santos AR, Lopes-Costa PV, Sousa-Júnior EC, Correa-Lima MV, Pires CG: Ovarian dermoid cyst with malignant transformation and rupture of the capsule associated with chemical peritonitis: a case report and literature review. Eur J Gynaecol Oncol; 2009;30(2):226-8
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  • [Title] Ovarian dermoid cyst with malignant transformation and rupture of the capsule associated with chemical peritonitis: a case report and literature review.
  • Malignant transformation of ovarian dermoid cysts is rare and spontaneous rupture provoking chemical peritonitis is even rarer.
  • Laparotomy in a 75-year-old Brazilian woman with abdominal pain and signs of peritoneal irritation revealed a voluminous right ovarian cyst with rupture of the capsule, an abundant quantity of fatty material in the abdominal cavity, and signs of peritonitis.
  • Histopathology confirmed a dermoid cyst with a well-differentiated area of epidermoid carcinoma.
  • Rupture of a dermoid cyst of the ovary resulting in chemical peritonitis is very rare and may be associated with malignant transformation.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Dermoid Cyst / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Peritonitis / etiology

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  • (PMID = 19480264.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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53. Hosokawa T, Sato Y, Seki T, Maebara M, Ito K, Kuribayashi S: Malignant transformation of a mature cystic teratoma of the ovary with rupture. Jpn J Radiol; 2010 Jun;28(5):372-5
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  • [Title] Malignant transformation of a mature cystic teratoma of the ovary with rupture.
  • Malignant transformation or tumor rupture is a rare complication of ovarian mature cystic teratomas.
  • We present computed tomography (CT) images of a 52-year-old woman that revealed a large, predominantly cystic mass filled with fat and enhanced solid components located in the lower abdomen.
  • Ten days later, the cystic mass ruptured, and massive ascites was observed on magnetic resonance imaging (MRI).
  • To our knowledge, there are no reports describing before and after images of a ruptured cystic teratoma with malignant transformation.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • [Cites] AJR Am J Roentgenol. 2004 Sep;183(3):743-50 [15333365.001]
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  • (PMID = 20585926.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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54. Driss M, Limaiem F, Mrad K, Charfi L, Abbes I, Sassi S, Hechiche M, Saadi A, Ben Romdhane K: [Malignant degeneration of benign cystic teratoma of the ovary with synchronous mediastinal teratoma. A case report]. Rev Med Interne; 2009 Apr;30(4):369-71
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  • [Title] [Malignant degeneration of benign cystic teratoma of the ovary with synchronous mediastinal teratoma. A case report].
  • [Transliterated title] Association synchrone d'un tératome de l'ovaire cancérisé associé à un tératome du médiastin. A propos d'un cas.
  • Squamous cell carcinoma arising in mature cystic teratoma of the ovary is an uncommon complication occurring usually in elderly woman.
  • We present an unusual case of a post-menopausal woman with a synchronous mediastinum teratoma.
  • While ovary tumor was symptomatic, mediastinal teratoma was an incidental finding.

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  • (PMID = 18722037.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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55. Bhuiyan ZH, Akhter N, Islam MF, Khan SA, Tawhid MH: Pilimiction. Mymensingh Med J; 2008 Jul;17(2 Suppl):S107-10
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  • It is pathognomonic sign of urinary bladder dermoid.
  • Primary bladder dermoid is very rare problem.
  • Secondary dermoid in the urinary bladder is not uncommon among the female specially during their reproductive life.
  • It is mostly ovarian origin.
  • Ovarian dermoid may grow and invade the urinary bladder wall to discharge its content in the urine.
  • Cystoscopic evaluation followed by laparotomy and excision of ovarian dermoid along its extension to the urinary bladder is a rational approach.
  • Our patient has benign indolent coarse of pilimiction for last 9 years.
  • Keeping an open mind we did cyst evaluation.
  • Attempt of endoscopic resection seems that the dermoid has invaded bladder wall from out side.
  • We did laparotomy in the same sitting. Lt. ovary was almost buried between the leaf of broad ligament and contain a dermoid cyst invading bladder wall to discharge its contents.
  • So we confirm our diagnosis as secondary bladder dermoids as a cause of pilimiction & excise the whole specimen keeping its safety margin.
  • Histopathologically it appears benign mature cystic teratoma.

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  • (PMID = 18946442.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
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56. Hurwitz JL, Fenton A, McCluggage WG, McKenna S: Squamous cell carcinoma arising in a dermoid cyst of the ovary: a case series. BJOG; 2007 Oct;114(10):1283-7
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  • [Title] Squamous cell carcinoma arising in a dermoid cyst of the ovary: a case series.
  • OBJECTIVE: Malignant transformation in a dermoid cyst of the ovary is a rare complication, occurring in only 1-2% of cases, with squamous cell carcinoma being the most common type.
  • Preoperative diagnosis is difficult because of the lack of specific symptoms and signs to suggest malignancy.
  • DESIGN: We identified 14 women with this diagnosis between 1989 and 2006.
  • This is a descriptive study, looking at the patient characteristics, mode of presentation and the role of tumour markers and radiological imaging in diagnosis.
  • RESULTS: We found that these tumours present at an age older than that of mature teratomas and that there are no reliable diagnostic tools or prognostic indicators.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Dermoid Cyst / pathology. Ovarian Neoplasms / pathology

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  • (PMID = 17877681.001).
  • [ISSN] 1471-0528
  • [Journal-full-title] BJOG : an international journal of obstetrics and gynaecology
  • [ISO-abbreviation] BJOG
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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57. Agaimy A, Lindner M, Wuensch PH: Interstitial cells of Cajal (ICC) in mature cystic teratoma of the ovary. Histopathology; 2006 Jan;48(2):208-9
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  • [Title] Interstitial cells of Cajal (ICC) in mature cystic teratoma of the ovary.
  • [MeSH-major] Dermoid Cyst / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16405675.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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58. Szpakowski M, Nowińska A, Kufelnicka M, Komorowski D, Wilczyński JR: [Laparoscopy or laparotomy in the treatment of ovarian teratomas?]. Ginekol Pol; 2006 Jul;77(7):502-9
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  • [Title] [Laparoscopy or laparotomy in the treatment of ovarian teratomas?].
  • BACKGROUND: Mature cystic teratomas (dermoid cyst), are the most common germ cell tumours of the ovary in women of reproductive age.
  • MATERIALS AND METHODS: 81 patients who had surgery in 3rd Departament of Gynecology and Obstetrics, University of Medicine, Lódź, from 2000 to 2005 for benign cystic teratomas were analyzed.
  • In 46 cases there were cystectomies performed sparing fragments of healthy ovarian tissue, in 24 cases ovariectomies and in 11 panhysterectomies were made.
  • All removed lesions histologically appeared benign cystis ovarian teratomas without any signs of malignancy.
  • CONCLUSIONS: The teratomas are composed of mature tissues derived from the three germ cell layers.
  • One of the possibility of ovarian teratoma's treatment is operative laparoscopy.
  • [MeSH-major] Laparoscopy. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / surgery. Teratoma / diagnosis. Teratoma / surgery

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  • (PMID = 17076199.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] pol
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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59. Raiga J, Djafer R, Benoit B, Treisser A: [Management of ovarian cysts]. J Chir (Paris); 2006 Sep-Oct;143(5):278-84
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  • [Title] [Management of ovarian cysts].
  • [Transliterated title] Prise en charge des kystes ovariens.
  • Ovarian cysts occur frequently in women of reproductive age.
  • These are usually functional cysts which resolve spontaneously and whose evolution can be followed with ultrasound.
  • Non-functional cysts have diverse histologic origins.
  • The most common are serous and mucinous cystadenomas which arise from the epithelial wall of the ovary, endometriomas which arise in the setting of pelvic endometriosis, and dermoid cysts which arise from the germinal cells of the ovary.
  • Endovaginal ultrasound with Doppler enhancement is the best imaging technique to establish the nature of cysts and to distinguish cysts suspicious for malignancy which require more invasive investigation.
  • Pelvic laparoscopy is the surgical approach of choice for the treatment of non-functional benign ovarian cysts.
  • Conservative treatment to shell out the cyst and preserve functional ovarian tissue should be reserved for women desirous of future pregnancies.
  • The risk of ovarian cancer remains a major preoccupation of the surgeon.
  • This article describes the diagnostic techniques which allow a laparoscopic approach to presumably benign cysts and discusses surgical techniques specifically adapted to their different histologic nature of ovarian cysts.
  • [MeSH-major] Ovarian Cysts / surgery
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cystadenoma, Mucinous / classification. Cystadenoma, Mucinous / surgery. Cystadenoma, Serous / classification. Cystadenoma, Serous / surgery. Dermoid Cyst / classification. Dermoid Cyst / surgery. Endometriosis / classification. Endometriosis / surgery. Female. Humans. Laparoscopy / contraindications. Laparoscopy / methods. Laparotomy. Magnetic Resonance Imaging. Ovarian Neoplasms / classification. Ovarian Neoplasms / surgery. Ultrasonography, Doppler

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  • (PMID = 17185953.001).
  • [ISSN] 0021-7697
  • [Journal-full-title] Journal de chirurgie
  • [ISO-abbreviation] J Chir (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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60. Kwon MJ, Nam ES, Cho SJ, Shin HS, Na YS, Chang JH, Kim IS: Bowel loop in an ovarian tumor: grossly visible, completely developed intestinal loop in mature cystic teratoma of malignant mixed germ cell tumor. Pathol Int; 2009 Jul;59(7):479-81
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  • [Title] Bowel loop in an ovarian tumor: grossly visible, completely developed intestinal loop in mature cystic teratoma of malignant mixed germ cell tumor.
  • Although a gastrointestinal-type epithelium is observed in 7-13% of mature cystic teratoma cases, the occurrence of a grossly visible, organized gastrointestinal loop formation is very rare.
  • Presented here is the case of a 14-year-old girl with malignant mixed germ cell tumor in the ovaries.
  • In her left ovary a grossly visible, intestinal loop, 9 cm long, with hanging mesentery attached to the cystic wall of a mature cystic teratoma associated with a yolk sac tumor was observed, and in her right ovary another mature cystic teratoma was observed.
  • [MeSH-major] Endodermal Sinus Tumor / pathology. Intestine, Large / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


61. Iwata A, Matsubara K, Umemoto Y, Hashimoto K, Fukaya T: Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl. J Pediatr Adolesc Gynecol; 2009 Oct;22(5):e121-3
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  • [Title] Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl.
  • BACKGROUND: Spontaneous rupture of benign cystic ovarian teratoma is an unusual occurrence.
  • Under a radiological diagnosis of cystic ovarian teratoma, she underwent laparoscopic cystectomy, preserving as much ovarian tissue as possible.
  • SUMMARY AND CONCLUSION: We present the youngest and first premenarcheal case of spontaneous rupture of cystic ovarian teratoma.
  • Early diagnosis and minimally invasive surgical procedure are essential to preserve future fertility.
  • [MeSH-major] Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19576813.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Hung PC, Fan KT, Lai HC, Shen CH, Luk HN: Postoperative paraplegia as a result of undiagnosed primitive neuroectodermal tumor, not epidural analgesia. J Chin Med Assoc; 2007 Oct;70(10):456-9
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  • Pathologic findings revealed that the abdominal mass was an ovarian dermoid cyst.

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  • (PMID = 17962148.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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63. Rubod C, Triboulet JP, Vinatier D: [Ovarian dermoid cyst complicated by chemical peritonitis. Case report]. Gynecol Obstet Fertil; 2007 Jul-Aug;35(7-8):651-3
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  • [Title] [Ovarian dermoid cyst complicated by chemical peritonitis. Case report].
  • [Transliterated title] Kyste dermoïde de l'ovaire compliqué d'une péritonite chimique. A propos d'un cas.
  • Dermoid cyst is the most frequent benign ovarian tumor.
  • We report a case of a patient who developed chemical peritonitis after laparoscopic management of ovarian dermoid cysts.
  • On the basis of this case, we aim to re-access the characteristics of dermoid cysts and highlight in particular the potential complication of chemical peritonitis and the following attitude to avoid this.
  • [MeSH-major] Dermoid Cyst / complications. Ovarian Cysts / complications. Peritonitis / complications

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  • (PMID = 17602847.001).
  • [ISSN] 1297-9589
  • [Journal-full-title] Gynécologie, obstétrique & fertilité
  • [ISO-abbreviation] Gynecol Obstet Fertil
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones
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64. López JI, de Santamaría IS, Claros IJ, Garmendia M, Gaafar A, Bilbao FJ: Prostatic remnants in mature cystic teratoma of the ovary. Ann Diagn Pathol; 2008 Oct;12(5):378-80
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  • [Title] Prostatic remnants in mature cystic teratoma of the ovary.
  • Mature cystic teratomas of the ovary containing prostatic remnants are reported in 2 women aged 31 and 20 years.
  • Both cases showed the expected histology of mature teratomas with a mixture of ecto- and endodermal structures lying in a fibrous stroma.
  • [MeSH-major] Ovarian Neoplasms / pathology. Prostate / pathology. Teratoma / pathology

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  • (PMID = 18774505.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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65. Laberge PY, Levesque S: Short-term morbidity and long-term recurrence rate of ovarian dermoid cysts treated by laparoscopy versus laparotomy. J Obstet Gynaecol Can; 2006 Sep;28(9):789-793
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  • [Title] Short-term morbidity and long-term recurrence rate of ovarian dermoid cysts treated by laparoscopy versus laparotomy.
  • OBJECTIVE: To compare the short-term morbidity and the long-term recurrence rate of ovarian dermoid cysts in women treated conservatively by laparoscopy with the outcomes in women treated by laparotomy.
  • METHODS: This retrospective multicentre cohort study compared the outcomes of removal of dermoid cysts by laparoscopy with removal by laparotomy.
  • All specimens were confirmed histologically as dermoid cysts.
  • We reviewed all medical records and identified all surgical interventions for dermoid cysts over a 10-year period (1993-2003) in two academic centres in Quebec City.
  • Of the 299 women treated for ovarian dermoid cysts, 167 were treated by laparotomy and 132 were treated by laparoscopy.
  • In total, 245 women with available follow-up were identified as having ovarian cystectomy (95 in the laparoscopy group and 150 in the laparotomy group).
  • RESULTS: The mean diameter of the cyst in women who had a laparotomy was significantly larger than in women who had laparoscopy (8.27 cm vs. 5.94 cm), and significantly more women in the laparotomy group had bilateral cysts (16% vs. 5% in the laparoscopy group).
  • Spillage of the cyst's contents occurred in 18% of cases in the laparoscopy group and in 1% in the laparotomy group.
  • Conversions of laparoscopy to laparotomy occurred in 11% of cases, mainly because of cyst size.
  • CONCLUSION: Ovarian cystectomy performed by laparoscopy is associated with a higher incidence of intra-abdominal spillage than laparotomy, but this not associated with any increase in morbidity.
  • [MeSH-major] Laparoscopy / methods. Laparotomy / methods. Ovarian Cysts / surgery. Postoperative Complications / epidemiology

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  • (PMID = 17022919.001).
  • [ISSN] 1701-2163
  • [Journal-full-title] Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
  • [ISO-abbreviation] J Obstet Gynaecol Can
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Netherlands
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66. Kefeli M, Kandemir B, Akpolat I, Yildirim A, Kokcu A: Rhabdomyosarcoma arising in a mature cystic teratoma with contralateral serous carcinoma: case report and review of the literature. Int J Gynecol Pathol; 2009 Jul;28(4):372-5
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  • [Title] Rhabdomyosarcoma arising in a mature cystic teratoma with contralateral serous carcinoma: case report and review of the literature.
  • SUMMARY: Malignant transformation of a mature cystic teratoma of the ovary is rare, and occurs in approximately 2% of all cases.
  • The most common malignancy arising in mature cystic teratoma is squamous cell carcinoma.
  • Sarcomas very rarely develop in mature cystic teratoma.
  • We describe the case of a 65-year-old patient with mature cystic teratoma, and with rhabdomyosarcomatous transformation and contralateral serous carcinoma.
  • To our knowledge, this is the first case of a pure rhabdomyosarcoma arising in a mature cystic teratoma.
  • [MeSH-major] Cystadenocarcinoma, Serous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Rhabdomyosarcoma / pathology. Teratoma / pathology

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  • (PMID = 19483625.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 31
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67. Marucci G, Collina G: [Mature cystic teratoma of the ovary with a small ganglioneuroma]. Pathologica; 2006 Feb;98(1):41-3
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  • [Title] [Mature cystic teratoma of the ovary with a small ganglioneuroma].
  • [Transliterated title] Teratoma cistico maturo ovarico con un piccolo ganglioneuroma.
  • A case of ganglioneuroma arising within a cystic mature teratoma of the ovary in a 34-year-old woman is reported.
  • The ovary was completely replaced by a bilocular cystic lesion, measuring 8 cm in diameter and filled with adipose tissue and pilosebaceous material.
  • Microscopically the cyst was composed by a mature cystic teratoma containing skin with dermal appendages, fatty tissue and bronchial epithelium.
  • Furthermore a nodule (0.5 cm in size) composed of mature ganglion cells, axons and Schwann cells, was identified.
  • To the best of our knowledgment this is the first reported cases of ganglioneuroma arisen within a cystic mature teratoma of the ovary.
  • [MeSH-major] Ganglioneuroma / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16789685.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / S100 Proteins; 0 / Synaptophysin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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68. Williams KM, Bain CJ, Kelly MD: Laparoscopic resection of a torted ovarian dermoid cyst. World J Emerg Surg; 2007;2:12
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  • [Title] Laparoscopic resection of a torted ovarian dermoid cyst.
  • Torsion or rupture of an ovarian cyst may present as an acute abdomen.
  • A case is presented where the diagnosis was made at laparoscopy and laparoscopic resection was done.
  • Controlled aspiration of the cyst contents allowed the cyst to be easily removed from the abdomen.

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  • [Cites] Fertil Steril. 1997 Sep;68(3):501-5 [9314922.001]
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  • (PMID = 17490490.001).
  • [ISSN] 1749-7922
  • [Journal-full-title] World journal of emergency surgery : WJES
  • [ISO-abbreviation] World J Emerg Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1876448
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69. Okada S, Ohaki Y, Inoue K, Nakajo H, Kawamata H, Kumazaki T: A case of dermoid cyst of the ovary with malignant transformation complicated with small intestinal fistula formation. Radiat Med; 2005 Sep;23(6):443-6
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  • [Title] A case of dermoid cyst of the ovary with malignant transformation complicated with small intestinal fistula formation.
  • CT showed a huge gas-containing cystic mass with fatty component and solid structure.
  • Emergency surgery was performed, and an enlarged left ovary that was adherent to the small intestine was removed.
  • Microscopic examination revealed a squamous cell carcinoma in the dermoid cyst wall.
  • The carcinoma had directly invaded the small intestine and a fistula between the cyst and the intestine was noted.
  • The histopathological diagnosis was dermoid cyst with malignant transformation and invasion of the small intestine.
  • [MeSH-major] Carcinoma, Squamous Cell / radiography. Cell Transformation, Neoplastic. Dermoid Cyst / radiography. Intestinal Fistula / radiography. Ovarian Neoplasms / radiography

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  • (PMID = 16389989.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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70. Khen-Dunlop N, Girot R, Brunelle F, Révillon Y, Nihoul-Fékété C, Sarnacki S: Surgical treatment of an unusual case of pelvic extramedullary hematopoiesis. J Pediatr Surg; 2006 Jul;41(7):e13-5
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  • Diagnosis and treatment of extramedullary hematopoiesis located in the pelvis of a young 15-year-old girl is discussed.
  • The young age of the patient and the uncommon site of the mass first lead to the diagnosis of an ovarian dermoid cyst.

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  • (PMID = 16818041.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Contreras AL, Malpica A: Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. Int J Gynecol Pathol; 2009 Sep;28(5):453-7
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  • [Title] Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature.
  • Mature cystic teratoma of the ovary is the most common ovarian tumor.
  • To date, only 5 cases of angiosarcoma arising in a mature cystic teratoma of the ovary have been reported.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19696615.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
  • [Number-of-references] 23
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72. Kim HS, Kim JW, Chung HH, Park NH, Song YS, Kang SB: Disease confined within the ovary and smaller amount of ascites are good prognostic factors for survival of patients with squamous cell carcinoma arising from mature cystic teratoma of the ovary: a case series in Korea and review of the published reports. J Obstet Gynaecol Res; 2009 Feb;35(1):99-105
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  • [Title] Disease confined within the ovary and smaller amount of ascites are good prognostic factors for survival of patients with squamous cell carcinoma arising from mature cystic teratoma of the ovary: a case series in Korea and review of the published reports.
  • AIM: To identify clinical prognostic factors for survival of patients with squamous cell carcinoma (SqCC) arising from mature cystic teratoma (MCT) of the ovary with review of the published reports.
  • METHODS: Clinical data of 55 patients with SqCC arising from MCT of the ovary who were reported in the Korean Journal of Obstetrics and Gynecology and the Korean Journal of Gynecologic Oncology and Colposcopy between 1992 and 2006 were reviewed.
  • RESULTS: Patients with disease confined within the ovary (n = 31) or ascites <500 mL (n = 15) had the benefit of a higher mean OS than those with advanced disease (n = 8) (116 vs 21 months, P = 0.004) and ascites > or =500 mL (n = 7) (106 vs 8 months, P = 0.005), respectively.
  • Disease confined within the ovary and ascites <500 mL were good prognostic factors by univariate but not multivariate Cox's proportional hazard analyses (HR = 0.123 and 0.139, 95% confidence interval = 0.022-0.670 and 0.027-0.722, respectively).
  • CONCLUSIONS: Disease confined within the ovary and a smaller amount of ascites may be good prognostic factors for the OS of patients with SqCC arising from MCT of the ovary.
  • [MeSH-major] Ascites / pathology. Carcinoma, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19215555.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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73. Lai PF, Hsieh SC, Chien JC, Fang CL, Chan WP, Yu C: Malignant transformation of an ovarian mature cystic teratoma: computed tomography findings. Arch Gynecol Obstet; 2005 Apr;271(4):355-7
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  • [Title] Malignant transformation of an ovarian mature cystic teratoma: computed tomography findings.
  • INTRODUCTION: The malignant transformation of an ovarian mature cystic teratoma is rare.
  • Computed tomography images showed a left adnexal mass with fat, calcification and soft tissue components, and areas of invasion through the teratoma wall.
  • OUTCOME: The histologic diagnosis was compatible with a squamous cell carcinoma arising from a mature cystic teratoma of the ovary.
  • [MeSH-major] Carcinoma, Squamous Cell / radiography. Ovarian Neoplasms / pathology. Ovarian Neoplasms / radiography. Teratoma / pathology. Teratoma / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 15551144.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CA-125 Antigen
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74. Karateke A, Gurbuz A, Kir G, Haliloglu B, Kabaca C, Devranoglu B, Yakut Y: Mucoepidermoid variant of adenosquamous carcinoma arising in ovarian dermoid cyst: a case report and review of the literature. Int J Gynecol Cancer; 2006 Jan-Feb;16 Suppl 1:379-84
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  • [Title] Mucoepidermoid variant of adenosquamous carcinoma arising in ovarian dermoid cyst: a case report and review of the literature.
  • A 40-year-old woman with mucoepidermoid variant of adenosquamous carcinoma arising in dermoid cyst in left ovary is presented.
  • To our best knowledge, this is 12th case of adenosquamous carcinoma in dermoid cyst and third case of mucoepidermoid variant of adenosquamous carcinoma in the literature.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Carcinoma, Adenosquamous / pathology. Carcinoma, Mucoepidermoid / pathology. Dermoid Cyst / complications. Ovarian Neoplasms / pathology

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  • (PMID = 16515628.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 20
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75. Santwani PM, Trivedi DP, Vachhani JH, Trivedi NJ: Coexistence of squamous cell carcinoma with dermoid cyst of ovary. Indian J Pathol Microbiol; 2008 Jan-Mar;51(1):81-2
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  • [Title] Coexistence of squamous cell carcinoma with dermoid cyst of ovary.
  • Ultrasonography showed partly cystic and solid area in mass arising from ovary.
  • Dermoid cyst was the diagnosis offered.
  • Ovarian mass with hair, a tooth and putty-like material was present.
  • Histopathology confirmed the findings of dermoid cyst and the thickened area showed squamous cell carcinoma with areas showing keratinous material and giant cell reaction which was also seen at the periphery of tumor areas.
  • Left ovary was normal and no deposits of tumor were seen.
  • [MeSH-major] Carcinoma, Squamous Cell / complications. Carcinoma, Squamous Cell / diagnosis. Dermoid Cyst / complications. Dermoid Cyst / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Laparotomy. Ovarian Diseases / complications. Ovarian Diseases / diagnosis. Ovarian Diseases / surgery. Ovarian Neoplasms / complications. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / surgery. Ovary / pathology. Ovary / ultrasonography

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  • (PMID = 18417868.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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76. Kyung MS, Choi JS, Hong SH, Kim HS: Elevated CA 19-9 levels in mature cystic teratoma of the ovary. Int J Biol Markers; 2009 Jan-Mar;24(1):52-6
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  • [Title] Elevated CA 19-9 levels in mature cystic teratoma of the ovary.
  • The purpose of this study was to evaluate the clinical value of serum tumor markers in patients with ovarian mature cystic teratoma (MCT).
  • We retrospectively evaluated 163 women who underwent surgery for MCT of the ovary between March 2003 and August 2007 and who provided preoperative blood samples for the measurement of CA 19-9 and CA 125.
  • The rate of ovarian torsion was 12.9% (21/163).
  • There were significant differences between the elevated CA 19-9 group and the normal CA 19-9 group in the diameters of the tumors and the rates of ovarian torsion.
  • CA 19-9 may be a useful tool for the diagnosis of ovarian MCT.
  • Elevated CA 19-9 levels appear to correlate with larger tumor diameters and higher rates of ovarian torsion.
  • [MeSH-major] Biomarkers, Tumor / blood. CA-19-9 Antigen / blood. Ovarian Neoplasms / blood. Teratoma / blood

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  • (PMID = 19404923.001).
  • [ISSN] 0393-6155
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / CA-19-9 Antigen
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77. Allam-Nandyala P, Bui MM, Caracciolo JT, Hakam A: Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature. Int J Clin Exp Pathol; 2010;3(3):313-8
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  • [Title] Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature.
  • A rare case of multiple malignant tumors (poorly differentiated squamous cell carcinoma and high grade osteosarcoma) arising in an ovarian dermoid cyst of a 55 year old female is reported.
  • To the best of our knowledge, this is the first well documented example of such an unusual combination of tumors arising in a dermoid cyst.
  • The osteosarcoma and squamous cell carcinoma appear to arise in the background of benign teratomatous environment of a dermoid cyst rather than from "pure" mixed mesodermal tumors of the ovary.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Dermoid Cyst / pathology. Osteosarcoma / secondary. Ovarian Neoplasms / pathology
  • [MeSH-minor] Combined Modality Therapy. Diagnosis, Differential. Fatal Outcome. Female. Humans. Middle Aged. Ovary / pathology

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  • (PMID = 20224730.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
  • [Other-IDs] NLM/ PMC2836509
  • [Keywords] NOTNLM ; Malignant dermoid / osteosarcoma / squamous cell carcinoma / teratoma
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78. Mohammad A, Makaju R: Retrospective histopathological analysis of various neoplasms of the female reproductive system (FRS) seen at the Kathmandu University Teaching Hospital, (KUTH) Dhulikhel, Nepal. Kathmandu Univ Med J (KUMJ); 2006 Jan-Mar;4(1):48-53
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  • Out of these, 1 (1.7%) was of the vagina (squamous cell carcinoma, papillary variant); 16 (26.7%) were of the cervix of the uterus (all squamous cell carcinoma in advanced stage); none were of the endometrium; 20 (33.3%) were of the body of the uterus/uterine muscle (all liomyomas); 16 (26.7%) were of the ovary, (11 benign, consisting of nine mature cystic tertoma, also known as dermoid cyst, one serous papillary cystdenoma and one mucinous cystadenoma; and, five malignant, consisting of two serous cystadenocarcinoma, two mucinous cystadenocarcinoma and one mixed mucinous and serous cystadenocarcinoma); and, 7 (11.6%) were of the breast (two benign, consisting of fibroadenoma and five malignant, all consisting of infiltrating ductal carcinoma in advanced stage).
  • [MeSH-minor] Adenocarcinoma / pathology. Breast Neoplasms / pathology. Carcinoma, Ductal / pathology. Carcinoma, Squamous Cell / pathology. Cystadenocarcinoma / pathology. Cystadenoma / pathology. Female. Fibroadenoma / pathology. Humans. Leiomyoma / pathology. Nepal. Ovarian Neoplasms / pathology. Retrospective Studies. Uterine Cervical Neoplasms / pathology. Uterine Neoplasms / pathology. Vaginal Neoplasms / pathology

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  • (PMID = 18603868.001).
  • [ISSN] 1812-2027
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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79. Coskun A, Kiran G, Ozdemir O: CA 19-9 can be a useful tumor marker in ovarian dermoid cysts. Clin Exp Obstet Gynecol; 2008;35(2):137-9
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  • [Title] CA 19-9 can be a useful tumor marker in ovarian dermoid cysts.
  • PURPOSE: To evaluate the importance of CA-19-9 as an aiding tool in the diagnosis of mature cystic teratomas.
  • METHODS: We found 43 cases of dermoid cysts that were operated on at our clinic, and whose tumor marker CA 19-9 was studied before the operation.
  • Thirty-one out of the 43 (72%) cases had a dermoid cyst in the right ovary, nine (20.9%) in the left ovary, and three (7%) had bilateral dermoid cysts.
  • CONCLUSION: We suggest that besides ultrasonography and computed tomography, serum CA 19-9 level could be a useful tumor marker in the diagnosis of dermoid cysts.
  • [MeSH-major] CA-19-9 Antigen / blood. Ovarian Neoplasms / diagnosis
  • [MeSH-minor] Adult. Dermoid Cyst / blood. Dermoid Cyst / diagnosis. Female. Humans

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  • (PMID = 18581770.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / CA-19-9 Antigen
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80. Tyler KL, Bell MC, Ziebarth JA: A rare case of squamous cell carcinoma arising in a mature cystic teratoma of the ovary. S D Med; 2007 Oct;60(10):401-3
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  • [Title] A rare case of squamous cell carcinoma arising in a mature cystic teratoma of the ovary.
  • Mature cystic teratoma is a common benign adnexal tumor in females.
  • We describe a 43-year-old female with a 10 cm left ovarian mature cystic teratoma with the rare finding of squamous cell carcinoma.
  • [MeSH-major] Neoplasms, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18019775.001).
  • [ISSN] 0038-3317
  • [Journal-full-title] South Dakota medicine : the journal of the South Dakota State Medical Association
  • [ISO-abbreviation] S D Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Khoo CK, Chua I, Siow A, Chern B: Parasitic dermoid cyst of the pouch of Douglas: a case report. J Minim Invasive Gynecol; 2008 Nov-Dec;15(6):761-3
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  • [Title] Parasitic dermoid cyst of the pouch of Douglas: a case report.
  • Extragonadal mature cystic teratomas (dermoid cysts) are reported occasionally, with the most common site being the omentum.
  • Of the 3 proposed causes of such cysts, torsion of a pre-existing dermoid, leading to autoamputation and subsequent reimplantation, is most likely the preceding event.
  • A rare case of a parasitic benign cystic teratoma was incidentally found in the pouch of Douglas in a 29-year-old woman undergoing a laparoscopic right cystectomy for an ovarian dermoid cyst.
  • A literature review indicates that this is the third reported case of a parasitic or wandering dermoid cyst of the pouch of Douglas.
  • [MeSH-major] Dermoid Cyst / surgery. Douglas' Pouch / pathology. Ovarian Neoplasms / surgery. Peritoneal Diseases / parasitology. Teratoma / surgery

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  • (PMID = 18971145.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Takeda A, Imoto S, Mori M, Sakai K, Nakamura H: Laparoscopic management of mature cystic teratoma of the ovary with multiple intracystic floating spherules. Arch Gynecol Obstet; 2009 May;279(5):775-6
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  • [Title] Laparoscopic management of mature cystic teratoma of the ovary with multiple intracystic floating spherules.
  • INTRODUCTION: A feature of multiple spherical structures floating free in a cystic mass is one of the very rare patterns of mature cystic teratoma.
  • Image diagnosis showed a large cystic tumor with unusual intracystic multiple floating spherules.
  • The histopathological diagnosis was mature cystic teratoma of the ovary with marked desquamative keratin formations.
  • CONCLUSIONS: After obtaining pathognomonic findings on diagnostic imaging, laparoscopic management of a rare form of mature cystic teratoma of the ovary with numerous intracystic floating spherules was successfully performed.
  • [MeSH-major] Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19037650.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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83. Chen E, Fletcher CD, Nucci MR: Meningothelial proliferations in mature cystic teratoma of the ovary: evidence for the common presence of cranially derived tissues paralleling anterior embryonic plate development. An analysis of 25 consecutive cases. Am J Surg Pathol; 2010 Jul;34(7):1014-8
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  • [Title] Meningothelial proliferations in mature cystic teratoma of the ovary: evidence for the common presence of cranially derived tissues paralleling anterior embryonic plate development. An analysis of 25 consecutive cases.
  • Mature cystic teratomas (MCTs) of the ovary are typically composed of a cyst lined with neoplastic tumor cells recapitulating ectodermal differentiation including derivatives such as epidermis, dermis, and appendages (sebaceous glands), although mesodermal and endodermal derivatives can also be seen.
  • Twenty-five consecutive cases of ovarian MCT (patient age ranging from 23 to 66 years, mean: 36.3 years; size ranging from 2.5 to 11.5 cm, mean: 6.1 cm) diagnosed in 2008 were retrieved from the archives at Brigham and Women's Hospital.
  • This study shows that the presence of meningothelial tissue in MCT of the ovary is quite frequent and its appearance is similar to that of EMH.
  • The similar morphologic appearance of the meningothelial proliferation in MCT to EMH, its localization to the dermal subcutaneous portion of MCT, and its frequent proximity to glial tissue supports the hypothesis that the tissue elements of ovarian MCT are primarily of the head and neck type (eg, scalp skin, brain, upper respiratory/sinonasal, and less commonly thyroid) suggesting that the neoplastic growth of MCT parallels normal anterior embryonic plate development with primarily the formation of the cranial (cephalad) portion of the embryo.
  • [MeSH-major] Hamartoma / pathology. Meninges / pathology. Nervous System Diseases / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


84. den Bakker MA, Ansink AC, Ewing-Graham PC: "Cutaneous-type" angiosarcoma arising in a mature cystic teratoma of the ovary. J Clin Pathol; 2006 Jun;59(6):658-60
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  • [Title] "Cutaneous-type" angiosarcoma arising in a mature cystic teratoma of the ovary.
  • Benign and malignant somatic tumours arising in mature cystic teratomas of the ovary are a rare but recognised phenomenon.
  • Squamous cell carcinoma is the most common somatic malignancy arising in ovarian teratomas, although many other types of tumour have been described.
  • An angiosarcoma with "cutaneous" type typical features arising in a dermoid cyst of the ovary is reported.
  • Vascular tumours have only rarely been described as secondary somatic tumours in ovarian teratomas.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16731607.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1860385
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85. Benoit MF, Hannigan EV, Strickland JL: Recurrent mature cystic ovarian teratoma in adolescence: atypical case of the growing teratoma syndrome. Obstet Gynecol; 2005 May;105(5 Pt 2):1264-6
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  • [Title] Recurrent mature cystic ovarian teratoma in adolescence: atypical case of the growing teratoma syndrome.
  • BACKGROUND: A primary mature cystic ovarian teratoma was diagnosed in an adolescent female.
  • Recurrent tumor, consisting solely of mature teratomatous elements, was confirmed with 2 subsequent laparotomies.
  • CASE: This is a report of the growing teratoma syndrome in a young woman with a primary diagnosis of a mature cystic ovarian teratoma not treated with adjuvant chemotherapy.
  • CONCLUSION: The growing teratoma syndrome is an uncommon condition.
  • [MeSH-major] Neoplasm Recurrence, Local / pathology. Ovarian Cysts / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 15863604.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Bal A, Mohan H, Singh SB, Sehgal A: Malignant transformation in mature cystic teratoma of the ovary: report of five cases and review of the literature. Arch Gynecol Obstet; 2007 Mar;275(3):179-82
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  • [Title] Malignant transformation in mature cystic teratoma of the ovary: report of five cases and review of the literature.
  • The incidence of malignant transformation in mature cystic teratoma (MCT) of the ovary is less than 2% as reported in gynaecological and pathological literature.
  • Here we present a series of five patients, who developed malignant transformation in MCT of the ovary, over a 6-year period (1999-2004).
  • The morphological and clinico-pathological features of malignant transformation in MCT of the ovary are discussed.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 16957908.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 14
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87. Alborzi S, Foroughinia L, Kumar PV, Asadi N, Alborzi S: A comparison of histopathologic findings of ovarian tissue inadvertently excised with endometrioma and other kinds of benign ovarian cyst in patients undergoing laparoscopy versus laparotomy. Fertil Steril; 2009 Dec;92(6):2004-7
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  • [Title] A comparison of histopathologic findings of ovarian tissue inadvertently excised with endometrioma and other kinds of benign ovarian cyst in patients undergoing laparoscopy versus laparotomy.
  • OBJECTIVE: To evaluate ovarian tissue inadvertently excised with benign cysts during laparotomy or laparoscopy.
  • PATIENT(S): 260 women, 20 to 35 years old, with unilateral benign ovarian cysts.
  • MAIN OUTCOME MEASURE(S): Histopathologic findings of ovarian tissue inadvertently excised in endometrioma compared with other kinds of benign cysts in laparoscopy versus laparotomy.
  • RESULT(S): In the laparoscopy group, ovarian tissue was present in 65% of endometrioma and in 32% of nonendometriotic cysts.
  • In the laparotomy group, ovarian tissue was seen in 80% of endometrioma and 41% of nonendometriotic cysts.
  • CONCLUSION(S): The surgical approach had no statistically significant impact on conservation of ovarian reserves.
  • The nature of the ovarian cyst played a greater role in the quality and quantity of the excised ovarian tissue.
  • [MeSH-major] Endometriosis / surgery. Laparoscopy / methods. Laparotomy / methods. Ovarian Cysts / surgery. Ovary / surgery
  • [MeSH-minor] Adult. Cystadenoma, Mucinous / pathology. Cystadenoma, Mucinous / surgery. Cystadenoma, Serous / pathology. Cystadenoma, Serous / surgery. Dermoid Cyst / pathology. Dermoid Cyst / surgery. Female. Fertility. Humans. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery. Prospective Studies. Young Adult

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  • (PMID = 18973882.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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88. Yamanaka Y, Tateiwa Y, Miyamoto H, Umemoto Y, Takeuchi Y, Katayama K, Hashimoto K: Preoperative diagnosis of malignant transformation in mature cystic teratoma of the ovary. Eur J Gynaecol Oncol; 2005;26(4):391-2
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  • [Title] Preoperative diagnosis of malignant transformation in mature cystic teratoma of the ovary.
  • OBJECTIVE: Malignant transformation of mature cystic teratomas (MCT) of the ovary is extremely rare.
  • There are no established criteria of diagnosis before surgery for carcinoma arising from MCT of the ovary.
  • Thus, we analyzed retrospectively tumor size and preoperative values of tumor markers in patients with MCT and investigated the possibility of preoperative diagnosis.
  • METHODS: This was a retrospective case series of 278 patients with MCT of the ovary.
  • Mean tumor size and serum SCC level were significantly higher than those of benign MCT.
  • [MeSH-major] Biomarkers, Tumor / blood. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / blood. Carcinoma, Squamous Cell / diagnosis. Cell Transformation, Neoplastic. Child. Female. Humans. Middle Aged. Predictive Value of Tests. Retrospective Studies

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  • (PMID = 16122185.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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89. Poduval A, Antal Z, Lee T, Bar A, Dalmau J, Muzumdar R: Immune-mediated encephalitis and virilization in association with a mature cystic ovarian teratoma in an adolescent girl. Horm Res; 2009;72(4):252-6
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  • [Title] Immune-mediated encephalitis and virilization in association with a mature cystic ovarian teratoma in an adolescent girl.
  • BACKGROUND: Mature cystic teratomas are the most common form of ovarian tumor in children and adolescents.
  • These tumors are mostly benign and non-secreting.
  • Virilization from an ovarian teratoma is exceptionally rare in pediatrics.
  • Equally rare is the association of ovarian teratomas with auto-immune encephalitis.
  • A large left ovarian tumor was seen on a CT scan.
  • Surgical excision revealed a mature cystic teratoma containing 6 liters of clear fluid with high androgen levels.
  • Antibodies to the N-methyl-D-aspartate receptor of the hippocampus were detected in pre-operatively archived serum, but undetectable 6 months postoperatively.
  • Immunohistochemistry studies on the tumor sections revealed that the antibodies in the patient's serum reacted with areas of the tumor expressing the N-methyl-D-aspartate receptor.
  • CONCLUSION: Both virilizing mature cystic teratomas and teratoma-associated encephalitis are extremely rare in the pediatric population.
  • [MeSH-major] Autoimmune Diseases / complications. Encephalitis / complications. Ovarian Neoplasms / complications. Teratoma / complications. Virilism / complications

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  • (PMID = 19786797.001).
  • [ISSN] 1423-0046
  • [Journal-full-title] Hormone research
  • [ISO-abbreviation] Horm. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Androgens; 0 / Autoantibodies; 0 / MAP2 protein, human; 0 / Microtubule-Associated Proteins; 0 / Receptors, N-Methyl-D-Aspartate
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90. Akbulut M, Zekioglu O, Terek MC, Ozdemir N: Florid vascular proliferation in mature cystic teratoma of the ovary: case report and review of the literature. Tumori; 2009 Jan-Feb;95(1):104-7
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  • [Title] Florid vascular proliferation in mature cystic teratoma of the ovary: case report and review of the literature.
  • A case of mature cystic teratoma that contained florid vascular proliferation is reported.
  • The ovarian tumor occurred in a 9-year-old girl; symptoms consisted of vomiting, abdominal pain and a palpable mass.
  • The microscopic findings were mostly typical of a mature cystic teratoma, but also abundant vascular proliferation mimicking hemangioma in association with mature neural tissue was observed.
  • Florid vascular proliferation may be seen in association with neural tissue of ovarian teratomas and should not be misdiagnosed as immature teratoma or a vascular neoplasm.
  • [MeSH-major] Neovascularization, Pathologic / pathology. Ovarian Neoplasms / blood supply. Ovarian Neoplasms / pathology. Teratoma / blood supply. Teratoma / pathology
  • [MeSH-minor] Actins / biosynthesis. Child. Diagnosis, Differential. Female. Hemangioma / pathology. Humans. Immunohistochemistry. Platelet Endothelial Cell Adhesion Molecule-1 / biosynthesis

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  • (PMID = 19366067.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Platelet Endothelial Cell Adhesion Molecule-1
  • [Number-of-references] 8
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91. Hascalik S, Celik O, Sarac K, Meydanli MM, Alkan A, Mizrak B: Metabolic changes in pelvic lesions: findings at proton MR spectroscopic imaging. Gynecol Obstet Invest; 2005;60(3):121-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Spectroscopy analysis of serous, mucinous and undifferentiated carcinoma of the ovary revealed Cho, lactate and lipid signals, but granulosa-theca cell tumor showed only a lipid signal.
  • The Cho signal was obtained from only 3 patients with mature cystic teratoma but none of the other benign ovarian tumors and pelvic abscesses.
  • A lipid signal was detected in 3 patients diagnosed with pelvic abscess and all benign ovarian tumors.
  • One case of endometrioma and 1 case of teratoma did not show any signal.
  • CONCLUSION: MRS demonstrates significant differences in metabolite concentration between benign and malignant ovarian tumors and pelvic abscesses.
  • MRS may therefore be helpful in the differential diagnosis of adnexal lesions.
  • [MeSH-minor] Abdominal Abscess / metabolism. Abdominal Abscess / pathology. Adult. Aged. Choline / metabolism. Creatine / metabolism. Dermoid Cyst / metabolism. Dermoid Cyst / pathology. Diagnosis, Differential. Endometriosis / metabolism. Endometriosis / pathology. Female. Granular Cell Tumor / metabolism. Granular Cell Tumor / pathology. Humans. Lipid Metabolism. Middle Aged. Neoplasms, Cystic, Mucinous, and Serous / metabolism. Neoplasms, Cystic, Mucinous, and Serous / pathology. Ovarian Neoplasms / metabolism. Ovarian Neoplasms / pathology. Protons. Teratoma / metabolism. Teratoma / pathology

  • Hazardous Substances Data Bank. CREATINE .
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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 15920339.001).
  • [ISSN] 0378-7346
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Protons; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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92. Yamaguchi K, Mandai M, Fukuhara K, Higuchi T, Hamanishi J, Takakura K, Fujii S: Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period. Oncol Rep; 2008 Mar;19(3):705-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period.
  • The aim of this study was to seek for factors which lead to the early diagnosis of malignant transformation from mature cystic teratoma.
  • Fourteen patients with malignant transformation from mature cystic teratoma of the ovary were analyzed retrospectively for precise clinicopathology and prognosis.
  • On the other hand, in benign cases, a false positive elevation of the serum SCC and CEA was observed in 23.5 and 14.3%, which turned out to be normal in 40 and 52.9% cases in the repeated study, respectively.
  • In conclusion neither imaging analysis nor tumor markers including SCC and CEA accurately diagnose malignant transformation of mature cystic teratoma in its early stage, suggesting that a combination of diagnostic means is important.
  • [MeSH-major] Cell Transformation, Neoplastic. Ovarian Neoplasms / pathology. Teratoma / pathology
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / blood. Carcinoma / diagnosis. Carcinoma / pathology. Carcinoma / radiography. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18288405.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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93. Bowling CB, Lipscomb GH: Torsion of the appendix mimicking ovarian torsion. Obstet Gynecol; 2006 Feb;107(2 Pt 2):466-7
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  • [Title] Torsion of the appendix mimicking ovarian torsion.
  • Computerized tomography showed an 8 x 4 cm mass anterior to the uterus, suggestive of degenerating fibroid versus ovarian dermoid cyst.
  • Laparoscopy was performed for presumed ovarian torsion.
  • CONCLUSION: Patients with presumed ovarian torsion should undergo urgent laparoscopy for diagnosis and attempted ovarian salvage.
  • [MeSH-major] Appendix. Cecal Diseases / diagnosis. Ovarian Diseases / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Torsion Abnormality / diagnosis

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  • (PMID = 16449151.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Dos Santos L, Mok E, Iasonos A, Park K, Soslow RA, Aghajanian C, Alektiar K, Barakat RR, Abu-Rustum NR: Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and review of the literature. Gynecol Oncol; 2007 May;105(2):321-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and review of the literature.
  • OBJECTIVES: Malignant transformation of mature cystic teratomas is rare, with squamous cell carcinoma being the most common type.
  • The prognosis is generally poor when disease has spread beyond the ovary.
  • METHODS: During a 22-year period (1983-2005), we identified 17 women treated for squamous cell carcinoma arising in a mature cystic teratoma of the ovary.
  • CONCLUSIONS: Squamous carcinomas arising in mature cystic teratomas are commonly large ovarian tumors that occur in perimenopausal women and often present as an incidental pathologic finding.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


95. Shintaku M: Corpora amylacea in a mature cystic teratoma of the ovary. Neuropathology; 2005 Jun;25(2):175-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Corpora amylacea in a mature cystic teratoma of the ovary.
  • [MeSH-major] Astrocytes. Dermoid Cyst / pathology. Inclusion Bodies / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 15875913.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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96. Katz L, Levy A, Wiznitzer A, Sheiner E: Pregnancy outcome of patients with dermoid and other benign ovarian cysts. Arch Gynecol Obstet; 2010 May;281(5):811-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pregnancy outcome of patients with dermoid and other benign ovarian cysts.
  • OBJECTIVE: To investigate pregnancy outcome of patients with dermoid and other benign ovarian cysts.
  • METHODS: A population-based study comparing all pregnancies of women with and without benign ovarian cysts was conducted.
  • A multivariate logistic regression model, with backward elimination, was constructed to find independent risk factors associated with benign ovarian cysts.
  • RESULTS: During the study period there were 212,114 deliveries, of which 93 occurred in patients with benign ovarian cysts.
  • Most of the lesions were benign cyatadenoma (41.9%), 36.7% were dermoid cyst, and 11.8% were adenofibroma, mostly diagnosed during cesarean delivery (76.3%).
  • The mean diameter at diagnosis was 9.05+/-7.6 cm for cystadenoma, 6.09+/-3.0 cm for dermoid cyst and 4.55+/-4.1 cm for adenofibroma.
  • Only 3 cases of ovarian torsion were noted (3.2%), and 15 cases of hospitalization due to abdominal pain (16.2%).
  • The following conditions were significantly associated with benign ovarian cysts: hypertensive disorder [odds ratio (OR) 3.05; 95% confidence interval (CI) 1.87-4.97], and maternal age (OR 1.04; 95% CI 1.01-1.07).
  • Ovarian dermoid cyst was significantly associated with fertility treatments (8.6 vs. 2.4% OR=3.75; 95% CI 1.1-12.2; P=0.019).
  • In addition, after controlling for maternal age using a multivariate analysis, fertility treatments remained significantly associated with ovarian dermoid.
  • CONCLUSION: The course of pregnancy of patients with dermoid and other benign ovarian cysts, including perinatal outcomes, is favorable.
  • The cysts should be managed conservatively if possible with routine ultrasound follow up during the pregnancy since complications are extremely rare.
  • [MeSH-major] Dermoid Cyst / epidemiology. Ovarian Cysts / epidemiology. Ovarian Neoplasms / epidemiology. Pregnancy Complications / epidemiology


97. Schubert B, Canis M, Darcha C, Artonne C, Pouly JL, Déchelotte P, Boucher D, Grizard G: Human ovarian tissue from cortex surrounding benign cysts: a model to study ovarian tissue cryopreservation. Hum Reprod; 2005 Jul;20(7):1786-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Human ovarian tissue from cortex surrounding benign cysts: a model to study ovarian tissue cryopreservation.
  • BACKGROUND: The scarcity of human ovarian tissue is a major problem in developing research on ovarian cryopreservation.
  • We were interested in ovarian cortex surrounding benign ovarian cysts harvested during their requisite operations.
  • METHODS: Ovarian tissue was collected from 25 women (mean age = 27.7 +/- 1.0 SEM) and frozen in serum-free cryoprotective medium.
  • RESULTS: Dermoid (n = 7), endometriosis (n = 13) and serous (n = 5) cysts were observed.
  • Follicular densities (expressed per mm3) in ovarian cortex surrounding dermoid cysts were higher than in endometriosis and serous cysts for both histological (median of follicular densities: 13.04, 0.31 and 0.89 respectively) and viability analysis (2.93, 0.05 and 0.71 respectively).
  • CONCLUSIONS: Ovarian cortex surrounding ovarian cysts, especially dermoid cysts, could be considered a source of ovarian tissue for future research.
  • [MeSH-major] Cryopreservation. Ovary. Tissue Preservation
  • [MeSH-minor] Adult. Female. Humans. Models, Biological. Ovarian Cysts / pathology

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  • (PMID = 15802317.001).
  • [ISSN] 0268-1161
  • [Journal-full-title] Human reproduction (Oxford, England)
  • [ISO-abbreviation] Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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98. Hong JH, Lee JK, Song SH, Hwang JH, So KA, Shin BK, Lee NW, Lee KW: Unilateral ovarian dermoid cyst accompanied by an ipsilateral paratubal cyst in a girl with Proteus Syndrome discovered by laparoscopic surgery. J Pediatr Adolesc Gynecol; 2010 Jun;23(3):e107-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unilateral ovarian dermoid cyst accompanied by an ipsilateral paratubal cyst in a girl with Proteus Syndrome discovered by laparoscopic surgery.
  • BACKGROUND: Proteus syndrome is a rare hamartomatous disorder characterized by the overgrowth of multiple tissues in a mosaic pattern.
  • CASE: We here report a 5-year-old girl with Proteus syndrome who developed a cystic mass in the pelvic cavity.
  • The cyst was discovered by ultrasonographic examination and finally proved to be a unilateral ovarian dermoid cyst accompanied by an ipsilateral paratubal cyst by laparoscopic surgery.
  • SUMMARY AND CONCLUSION: Proteus syndrome accompanied by an ovarian cyst is rare in girls.
  • The possibilities of underlying ovarian cyst required for surgical intervention should be considered in Proteus syndrome.
  • [MeSH-major] Dermoid Cyst / complications. Laparoscopy. Ovarian Cysts / complications. Parovarian Cyst / complications. Parovarian Cyst / diagnosis. Teratoma / complications

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  • [Copyright] Copyright 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19833537.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. von Gunten M, Burger H, Vajtai I: Choroid plexus papilloma developing in a dermoid cyst of ovary. Histopathology; 2006 Aug;49(2):204-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroid plexus papilloma developing in a dermoid cyst of ovary.
  • [MeSH-major] Dermoid Cyst / pathology. Ovarian Neoplasms / pathology. Papilloma, Choroid Plexus / pathology
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Prealbumin / analysis. S100 Proteins / analysis. Vimentin / analysis

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  • (PMID = 16879402.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Prealbumin; 0 / S100 Proteins; 0 / Vimentin
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100. Kajo K, Macháleková K: Collision of invasive serous adenocarcinoma and mature cystic teratoma in the ovary. Letter to the editor. APMIS; 2007 Jun;115(6):769-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Collision of invasive serous adenocarcinoma and mature cystic teratoma in the ovary. Letter to the editor.
  • [MeSH-major] Adenocarcinoma / complications. Ovarian Neoplasms / complications. Teratoma / complications

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  • [CommentOn] APMIS. 2005 Oct;113(10):713-5 [16309432.001]
  • (PMID = 17550386.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Denmark
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