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1. Einspahr JG, Thomas TL, Saboda K, Nickolof BJ, Warneke J, Curiel-Lewandrowski C, Ranger-Moore J, Duckett L, Bangert J, Fruehauf JP, Alberts DS: Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression. Cancer; 2007 Dec 1;110(11):2519-27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression.
  • BACKGROUND: A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN).
  • Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesis could be useful as chemoprevention and prognostic markers.
  • METHODS: Markers of angiogenesis that included expression of the vascular endothelial growth factor A (VEGF-A) and microvessel density counts (MVD) were evaluated in 13 prospectively collected benign nevi (BN) and 19 DN from 16 individuals and in a comparison group of 17 primary melanomas (16 archival samples and 1 prospective melanoma).
  • [MeSH-major] Melanoma / metabolism. Skin Neoplasms / metabolism. Vascular Endothelial Growth Factor A / metabolism
  • [MeSH-minor] Biomarkers, Tumor. Disease Progression. Dysplastic Nevus Syndrome / metabolism. Female. Humans. Immunohistochemistry. Male. Microcirculation. Middle Aged. Neovascularization, Pathologic. Nevus / metabolism. Prospective Studies

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  • [Copyright] Copyright (c) 2007 American Cancer Society.
  • (PMID = 17932890.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA23074; United States / NCI NIH HHS / CA / CA27502
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A
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2. Bachmann IM, Ladstein RG, Straume O, Naumov GN, Akslen LA: Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer; 2008;8:362
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  • [Title] Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas.
  • BACKGROUND: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas.
  • Our hypothesis was that rapid growth in cutaneous melanomas of the vertical growth phase might lead to tissue hypoxia, alterations in apoptotic activity and tumor necrosis.
  • We proposed that these tumor characteristics might be associated with changes in expression of cell adhesion proteins leading to increased invasive capacity and reduced patient survival.
  • METHODS: A well characterized series of nodular melanoma (originally 202 cases) and other benign and malignant melanocytic tumors (109 cases) were examined for the presence of necrosis, apoptotic activity (TUNEL assay), immunohistochemical expression of hypoxia markers (HIF-1 alpha, CAIX, TNF-alpha, Apaf-1) and cell adhesion proteins (alphavbeta3 integrin, CD44/HCAM and osteopontin).
  • We hypothesized that tumor hypoxia and necrosis might be associated with increased invasiveness in melanoma through alterations of tumor cell adhesion proteins.
  • RESULTS: Necrosis was present in 29% of nodular melanomas and was associated with increased tumor thickness, tumor ulceration, vascular invasion, higher tumor proliferation and apoptotic index, increased expression of alphavbeta3 integrin and poor patient outcome by multivariate analysis.
  • Tumor cell apoptosis did also correlate with reduced patient survival.
  • Expression of TNF-alpha and Apaf-1 was significantly associated with tumor thickness, and osteopontin expression correlated with increased tumor cell proliferation (Ki-67).
  • CONCLUSION: Tumor necrosis and apoptotic activity are important features of melanoma progression and prognosis, at least partly through alterations in cell adhesion molecules such as increased alphavbeta3 integrin expression, revealing potentially important targets for new therapeutic approaches to be further explored.
  • [MeSH-major] Integrin alphaVbeta3 / metabolism. Melanoma / metabolism. Melanoma / pathology. Necrosis. Skin Neoplasms / metabolism. Skin Neoplasms / pathology
  • [MeSH-minor] Antigens, CD44 / metabolism. Apoptosis. Biomarkers, Tumor / metabolism. Cell Hypoxia / physiology. Gene Expression Regulation, Neoplastic. Humans. In Situ Nick-End Labeling. Kaplan-Meier Estimate. Multivariate Analysis. Osteopontin / metabolism. Prognosis. Retrospective Studies. Statistics, Nonparametric. Survival Analysis. Tissue Array Analysis

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  • [Cites] Melanoma Res. 2004 Feb;14(1):29-37 [15091191.001]
  • [Cites] Clin Cancer Res. 2000 May;6(5):1845-53 [10815907.001]
  • [Cites] Int J Cancer. 2004 Oct 20;112(1):61-70 [15305376.001]
  • [Cites] J Bone Miner Res. 2004 Oct;19(10):1706-11 [15355566.001]
  • [Cites] Int J Cancer. 2000 Sep 1;87(5):716-23 [10925366.001]
  • [Cites] Am J Pathol. 2000 Aug;157(2):411-21 [10934146.001]
  • [Cites] Eur J Cell Biol. 2000 Jul;79(7):502-12 [10961450.001]
  • [Cites] Am J Pathol. 2000 Sep;157(3):957-65 [10980134.001]
  • [Cites] Am J Pathol. 2000 Nov;157(5):1415-30 [11073801.001]
  • [Cites] Am J Pathol. 2001 Mar;158(3):905-19 [11238039.001]
  • [Cites] Am J Pathol. 2001 Jul;159(1):223-35 [11438469.001]
  • [Cites] J Pathol. 2001 Jul;194(3):349-57 [11439368.001]
  • [Cites] J Clin Oncol. 2001 Aug 15;19(16):3660-8 [11504747.001]
  • [Cites] Cancer Res. 2001 Nov 1;61(21):7992-8 [11691824.001]
  • [Cites] Am J Pathol. 2002 Mar;160(3):1009-19 [11891198.001]
  • [Cites] Mod Pathol. 2002 Apr;15(4):387-96 [11950912.001]
  • [Cites] Cytopathology. 2002 Feb;13(1):11-21 [11985564.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Jul 15;53(4):854-61 [12095550.001]
  • [Cites] Int J Cancer. 2002 Sep 10;101(2):156-67 [12209993.001]
  • [Cites] Connect Tissue Res. 2002;43(2-3):308-19 [12489175.001]
  • [Cites] Cancer Biol Ther. 2002 Sep-Oct;1(5):459-65 [12496470.001]
  • [Cites] Cancer Cell. 2003 Jan;3(1):17-22 [12559172.001]
  • [Cites] Cell Cycle. 2004 Feb;3(2):164-7 [14712082.001]
  • [Cites] Exp Dermatol. 2004 Feb;13(2):93-7 [15009102.001]
  • [Cites] Br J Cancer. 2004 Sep 13;91(6):1089-95 [15305193.001]
  • [Cites] Cancer Res. 1969 Mar;29(3):705-27 [5773814.001]
  • [Cites] Ann Surg. 1970 Nov;172(5):902-8 [5477666.001]
  • [Cites] Adv Immunol. 1993;54:271-335 [8379464.001]
  • [Cites] J Clin Pathol. 1995 Mar;48(3):242-4 [7730486.001]
  • [Cites] J Surg Res. 1996 Jun;63(1):169-73 [8661192.001]
  • [Cites] Eur J Cancer. 1997 May;33(6):926-30 [9291817.001]
  • [Cites] Int J Cancer. 1997 Oct 21;74(5):535-9 [9355977.001]
  • [Cites] J Cutan Pathol. 1998 Apr;25(4):199-203 [9609138.001]
  • [Cites] Nat Med. 1998 Jul;4(7):844-7 [9662379.001]
  • [Cites] Br J Dermatol. 1998 May;138(5):763-8 [9666819.001]
  • [Cites] Am J Pathol. 1998 Nov;153(5):1435-42 [9811334.001]
  • [Cites] Hum Pathol. 1999 May;30(5):562-7 [10333228.001]
  • [Cites] Int J Oncol. 1999 Sep;15(3):595-9 [10427146.001]
  • [Cites] Cancer Res. 2005 Mar 15;65(6):2387-96 [15781654.001]
  • [Cites] Mol Biol Cell. 2005 Apr;16(4):1901-12 [15689487.001]
  • [Cites] Clin Cancer Res. 2005 Apr 1;11(7):2583-90 [15814637.001]
  • [Cites] J Invest Dermatol. 2005 May;124(5):1044-52 [15854047.001]
  • [Cites] Int J Cancer. 2005 Sep 20;116(5):734-9 [15849727.001]
  • [Cites] Exp Dermatol. 2005 Nov;14(11):811-8 [16232302.001]
  • [Cites] Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8606-14 [16361544.001]
  • [Cites] Pigment Cell Res. 2006 Feb;19(1):43-50 [16420245.001]
  • [Cites] Cancer Metastasis Rev. 2007 Jun;26(2):225-39 [17440684.001]
  • [Cites] Cancer. 2008 Jan 1;112(1):144-50 [18023025.001]
  • [Cites] J Cell Sci. 2000 May;113 ( Pt 9):1535-42 [10751145.001]
  • [Cites] Int J Cancer. 2004 Aug 10;111(1):43-50 [15185341.001]
  • (PMID = 19061491.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor; 0 / CD44 protein, human; 0 / Integrin alphaVbeta3; 106441-73-0 / Osteopontin
  • [Other-IDs] NLM/ PMC2631589
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3. Vilallonga R, Espin Basany E, Armengol M: Cavernous hemangioma: unusual benign tumor of the transverse colon. Turk J Gastroenterol; 2009 Jun;20(2):146-9
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  • [Title] Cavernous hemangioma: unusual benign tumor of the transverse colon.
  • Colonic hemangiomas are very rare vascular malformations and their clinical presentation is usually acute, recurrent or chronic rectal bleeding.
  • This tumor can be diagnosed as solitary, multiple, or part of a more complex syndrome with cutaneous manifestations.

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  • (PMID = 19530050.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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4. Massi D, Landriscina M, Piscazzi A, Cosci E, Kirov A, Paglierani M, Di Serio C, Mourmouras V, Fumagalli S, Biagioli M, Prudovsky I, Miracco C, Santucci M, Marchionni N, Tarantini F: S100A13 is a new angiogenic marker in human melanoma. Mod Pathol; 2010 Jun;23(6):804-13
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  • Angiogenesis is critical in melanoma progression and metastasis and relies on the synthesis and release of proangiogenic molecules such as vascular endothelial growth factor (VEGF)-A and fibroblast growth factors (FGFs).
  • S100A13 is upregulated in astrocytic gliomas, in which it correlates with VEGF-A expression, microvessel density and tumor grading, and promotes a more aggressive, invasive phenotype in lung cancer-derived cell lines.
  • To investigate the involvement of S100A13 in human cutaneous melanoma, we analyzed a series of 87 cutaneous melanocytic lesions: 14 common acquired melanocytic nevi, 14 atypical, so-called 'dysplastic' nevi, 45 melanomas (17 radial growth phase and 28 vertical growth phase) and 14 melanoma metastases.
  • We found that S100A13 was expressed in melanocytic lesions; compared with benign nevi, S100A13 protein expression was significantly upregulated in melanomas (P=0.024), in which it correlated positively with the intensity of VEGF-A staining (P=0.041) and microvessel density (P=0.007).
  • In conclusion, S100A13 is expressed in melanocytic lesions when the angiogenic switch occurs and it may cooperate with VEGF-A in supporting the formation of new blood vessels, favoring the shift from radial to vertical tumor growth.
  • [MeSH-major] Biomarkers, Tumor / analysis. Capillaries / chemistry. Melanoma / blood supply. Melanoma / chemistry. Neovascularization, Pathologic / metabolism. S100 Proteins / analysis. Skin Neoplasms / blood supply. Skin Neoplasms / chemistry
  • [MeSH-minor] Aged. Antigens, CD / analysis. Female. Fibroblast Growth Factor 1 / analysis. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Prognosis. RNA, Messenger / analysis. Receptors, Cell Surface / analysis. Reverse Transcriptase Polymerase Chain Reaction. Up-Regulation. Vascular Endothelial Growth Factor A / analysis

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  • [Cites] Crit Rev Oncol Hematol. 2000 Jun;34(3):185-94 [10838264.001]
  • [Cites] J Clin Oncol. 2009 Dec 20;27(36):6199-206 [19917835.001]
  • [Cites] J Biol Chem. 2001 Jun 22;276(25):22544-52 [11410600.001]
  • [Cites] Am J Pathol. 2001 Jul;159(1):223-35 [11438469.001]
  • [Cites] J Clin Oncol. 2001 Aug 15;19(16):3635-48 [11504745.001]
  • [Cites] J Clin Oncol. 2002 Apr 1;20(7):1826-31 [11919240.001]
  • [Cites] FASEB J. 2003 Jun;17(9):984-92 [12773481.001]
  • [Cites] Mod Pathol. 2004 Aug;17(8):990-7 [15133476.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Oct 1;322(4):1111-22 [15336958.001]
  • [Cites] Reprod Domest Anim. 2004 Oct;39(5):321-7 [15367264.001]
  • [Cites] Semin Oncol. 1975 Jun;2(2):119-47 [1234372.001]
  • [Cites] Science. 1984 Aug 31;225(4665):932-5 [6382607.001]
  • [Cites] Am J Pathol. 1993 Jul;143(1):99-104 [7686347.001]
  • [Cites] Cancer Res. 1993 Dec 15;53(24):6061-6 [8261423.001]
  • [Cites] Am J Pathol. 1994 Feb;144(2):329-36 [8311116.001]
  • [Cites] J Biol Chem. 1995 Dec 8;270(49):29039-42 [7493920.001]
  • [Cites] J Invest Dermatol. 1996 Feb;106(2):207-8 [8601716.001]
  • [Cites] Melanoma Res. 1996 Apr;6(2):133-7 [8791271.001]
  • [Cites] Melanoma Res. 1996 Jun;6(3):223-30 [8819125.001]
  • [Cites] J Cutan Pathol. 1997 Apr;24(4):212-8 [9138111.001]
  • [Cites] Surg Oncol Clin N Am. 1997 Jul;6(3):599-623 [9210357.001]
  • [Cites] Int J Cancer. 1997 Aug 22;74(4):464-9 [9291441.001]
  • [Cites] J Cell Biol. 1998 Jun 29;141(7):1659-73 [9647657.001]
  • [Cites] Ann Surg Oncol. 1999 Jan-Feb;6(1):70-4 [10030417.001]
  • [Cites] Mod Pathol. 1999 Aug;12(8):770-4 [10463478.001]
  • [Cites] Reprod Biol. 2005 Mar;5(1):51-67 [15821778.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):159-78 [15863032.001]
  • [Cites] Br J Cancer. 2005 Jun 6;92(11):1955-8 [15900299.001]
  • [Cites] Cancer Res. 2005 Jun 15;65(12):4993-7 [15958538.001]
  • [Cites] J Reprod Immunol. 2005 Oct;67(1-2):87-101 [16165218.001]
  • [Cites] Biochem J. 2006 Jun 1;396(2):201-14 [16683912.001]
  • [Cites] J Neurooncol. 2006 Dec;80(3):251-9 [16773219.001]
  • [Cites] Semin Oncol. 2007 Dec;34(6):555-65 [18083379.001]
  • [Cites] Eur J Cancer. 2008 Jan;44(1):151-9 [18061437.001]
  • [Cites] Eur J Surg Oncol. 2008 Apr;34(4):357-64 [17566693.001]
  • [Cites] J Cell Biochem. 2008 Apr 1;103(5):1327-43 [17786931.001]
  • [Cites] J Cutan Pathol. 2008 May;35(5):433-44 [18399807.001]
  • [Cites] Neoplasma. 2008;55(4):273-9 [18505336.001]
  • [Cites] Cancer Lett. 2008 Aug 18;267(1):67-74 [18400376.001]
  • [Cites] Mod Pathol. 2009 Jan;22(1):21-30 [18660796.001]
  • [Cites] Ann Oncol. 2009 Aug;20 Suppl 6:vi8-13 [19617299.001]
  • [Cites] Cancer Res. 2001 Feb 15;61(4):1717-26 [11245488.001]
  • (PMID = 20208480.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL035627; United States / NHLBI NIH HHS / HL / R01 HL035627; United States / NHLBI NIH HHS / HL / R01 HL035627-23
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / ENG protein, human; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 0 / S100 Proteins; 0 / S100A13 protein, human; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 104781-85-3 / Fibroblast Growth Factor 1
  • [Other-IDs] NLM/ NIHMS204422; NLM/ PMC2882157
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5. Nishikawa Y, Kaneko T, Takiyoshi N, Aizu T, Nakajima K, Matsuzaki Y, Nakano H, Sawamura D: Dermoscopy of eccrine poroma with calcification. J Dermatol Case Rep; 2009 Nov 28;3(3):38-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Eccrine poromas are relatively common slow-growing benign solitary adnexal tumors originating from the intraepidermal portion of the eccrine sweat duct (acrosyringium).
  • MAIN OBSERVATIONS: A 73-year-old man with hemiparesis, who had a 10-year history of tumor on his right palm, which was occasionally injured by a walking crutch, causing bleeding and ulceration.
  • Physical examination revealed a pigmented dome-shaped tumor.
  • Histological examination revealed that the tumor was composed of cords of tumor cells extending from the epidermis into the dermis.
  • These were uniformly cuboidal cells with round, basophilic nuclei and dense vascular stromas with telangiectasia.
  • The tumor showed cystic structures and calcification.
  • CONCLUSIONS: Although cutaneous neoplasms commonly associated with calcification are of follicular origin, it is known that dystrophic calcification may be triggered also in tumors of eccrine origin by multiple factors, including mechanical injury.

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  • [Cites] Br J Dermatol. 2001 Jan;144(1):146-50 [11167697.001]
  • [Cites] Dermatol Surg. 2003 Oct;29(10):1076-9 [12974711.001]
  • [Cites] J Am Acad Dermatol. 2007 Jul;57(1):84-95 [17482314.001]
  • [Cites] J Am Acad Dermatol. 1995 Nov;33(5 Pt 1):693-706; quiz 707-10 [7593766.001]
  • [Cites] Acta Derm Venereol. 2009;89(2):160-4 [19326001.001]
  • [Cites] J Dermatol. 1994 Dec;21(12):979-81 [7868774.001]
  • [Cites] Dermatology. 2007;215(2):160-3 [17684381.001]
  • (PMID = 21886728.001).
  • [ISSN] 1898-7249
  • [Journal-full-title] Journal of dermatological case reports
  • [ISO-abbreviation] J Dermatol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC3157797
  • [Keywords] NOTNLM ; Pinkus type / adnexal tumors / calcification / dermoscopy / eccrine gland / local tissue injury
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6. Makino E, Yamada J, Tada J, Arata J, Iwatsuki K: Cutaneous angiolipoleiomyoma. J Am Acad Dermatol; 2006 Jan;54(1):167-71
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  • [Title] Cutaneous angiolipoleiomyoma.
  • We describe a girl with cutaneous angiolipoleiomyoma on the buttock.
  • The 16-year-old girl had a 2.5- x 1.5-cm subcutaneous tumor on the right buttock, which was slightly tender.
  • The tumor appeared to be vascular and was, therefore, surgically excised.
  • Cutaneous angiomyolipoma, which is also known as cutaneous angiolipoleiomyoma, is a rare benign mesenchymal tumor.
  • We point out the differences between the cutaneous and renal forms of angiomyolipoma, and conclude that the cutaneous lesion is distinct from a renal lesion in several aspects, including tuberous sclerosis complex association and immunoreactivity to both HMB-45 and MART-1.
  • [MeSH-major] Angiomyolipoma / diagnosis. Buttocks. Skin Neoplasms / diagnosis

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  • (PMID = 16384779.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Sturgeon BP, Milne EM, Smith KC: Benign peripheral nerve sheath tumor of the perianal region in a young pony. J Vet Diagn Invest; 2008 Jan;20(1):93-6
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  • [Title] Benign peripheral nerve sheath tumor of the perianal region in a young pony.
  • The whorls were often arranged around a central structure resembling an axon or a vascular structure.
  • On the basis of the histopathology and immunohistochemistry, a diagnosis of benign peripheral nerve sheath tumor (schwannoma type) was made.
  • This case was unusual in that the concentric laminations of Schwann cells were very loosely arranged, with an intervening myxomatous stroma (Antoni type B appearance) and despite its benign histological appearance, the mass extended deeply to the proximal sacral vertebrae.
  • Its exact origin was unclear; it may have arisen from cutaneous nerves with deep extension or from neural structures in the sacral region.
  • [MeSH-minor] Animals. Horses. Immunohistochemistry / veterinary. Male. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / veterinary

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  • (PMID = 18182519.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Reis RM, Reis-Filho JS, Longatto Filho A, Tomarev S, Silva P, Lopes JM: Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors. Pathol Res Pract; 2005;201(12):771-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors.
  • Here, we describe a double-immunostaining strategy for formalin-fixed, paraffin-embedded tissues that aims at evaluating the distribution of Prox-1 and CD 31 - a cytoplasmic pan-endothelial marker - in a series of 28 mucousae, cutaneous and soft tissue vascular lesions and tumors, including hemangiomas, lymphangiomas, lymphangiectasia, and Kaposi's sarcomas.
  • Our results showed that in non-lesional mucousae and skin, Prox-1 decorated exclusively the nuclei of endothelial cells in lymphatic vessels.
  • Prox-1 stained almost all the benign lymphatic vascular lesions/tumors (91%) and was absent or only focally positive in 75% of blood vascular tumors.
  • CD 31 stained endothelial cells of blood vessels of superficial and deep dermal plexuses, lymphatics, and all blood vascular lesions/tumors.
  • In conclusion, although Prox-1 expression in vascular lesions/tumors was not entirely restricted to tumors with known lymphatic differentiation, CD 31/Prox-1 double-immunolabeling can be used as an adjunct marker to identify lymphatic vessels in routinely processed formalin-fixed, paraffin-embedded samples.
  • [MeSH-major] Antigens, CD31 / metabolism. Endothelial Cells / metabolism. Homeodomain Proteins / metabolism. Mucous Membrane / metabolism. Skin / metabolism. Soft Tissue Neoplasms / metabolism. Vascular Neoplasms / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers / analysis. Child. Child, Preschool. Female. Hemangioma / metabolism. Humans. Immunohistochemistry. Infant. Infant, Newborn. Lymphangioma / metabolism. Lymphatic Vessels / metabolism. Male. Middle Aged. Sarcoma, Kaposi / metabolism. Tumor Suppressor Proteins

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  • (PMID = 16308102.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers; 0 / Homeodomain Proteins; 0 / Tumor Suppressor Proteins; 0 / prospero-related homeobox 1 protein
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9. Gleason BC, Fletcher CD: Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol; 2008 Mar;32(3):354-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential.
  • Benign fibrous histiocytoma (FH) is one of the most common mesenchymal neoplasms of the skin.
  • Several histologic variants of cutaneous FH have been described, some of which also have distinct clinical features including a propensity for local recurrence.
  • Deep benign FH is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue.
  • Other common findings included a hemangiopericytomalike vascular pattern (42%) and stromal hyalinization (39%).
  • Of the 37 patients for whom clinical follow-up was available (median, 40 mo), 8 (22%) had a local recurrence; in all 8 cases, the tumor had been marginally or incompletely excised.
  • The metastasizing tumors were large (6 and 9 cm) and 1 had tumor necrosis but they were otherwise histologically identical to the nonmetastasizing lesions.
  • In summary, deep FH has many histologic features in common with cutaneous cellular FH; however, it usually has a more diffusely storiform pattern than the latter, is well circumscribed, and may have striking hemangiopericytomalike vessels.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasm Metastasis / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD34 / analysis. Child. Desmin / analysis. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mitosis. Necrosis. Neoplasm Recurrence, Local

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  • (PMID = 18300816.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin
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10. Clarke LE, Lee R, Militello G, Elenitsas R, Junkins-Hopkins J: Cutaneous epithelioid hemangioendothelioma. J Cutan Pathol; 2008 Feb;35(2):236-40
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  • [Title] Cutaneous epithelioid hemangioendothelioma.
  • Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of endothelial cell origin.
  • We discuss the clinical and histopathologic differential diagnoses for these tumors and review additional cases in which EHE has been mistaken for benign entities clinically.
  • [MeSH-major] Diagnostic Errors. Foot Diseases / pathology. Hemangioendothelioma, Epithelioid / pathology. Skin Neoplasms / pathology

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  • (PMID = 18190452.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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11. Messeguer F, Sanmartín O, Martorell-Calatayud A, Nagore E, Requena C, Guillén-Barona C: [Acquired progressive lymphangioma (benign lymphangioendothelioma)]. Actas Dermosifiliogr; 2010 Nov;101(9):792-7
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  • [Title] [Acquired progressive lymphangioma (benign lymphangioendothelioma)].
  • [Transliterated title] Linfangioma progresivo adquirido (linfangioendotelioma benigno).
  • Acquired progressive lymphangioma is a rare vascular tumor with a locally aggressive behavior.
  • The tumor was in the hypogastric region and had arisen on a congenital vascular lesion previously diagnosed as multifocal cutaneous angiomatosis.
  • [MeSH-major] Lymphangioma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Angiomatosis / congenital. Angiomatosis / pathology. Disease Progression. Edema / etiology. Humans. Male. Movement Disorders / etiology. Pain / etiology. Skin Diseases / congenital. Skin Diseases / pathology

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  • (PMID = 21034710.001).
  • [ISSN] 1578-2190
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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12. Chen SY, Takeuchi S, Urabe K, Hayashida S, Kido M, Tomoeda H, Uchi H, Dainichi T, Takahara M, Shibata S, Tu YT, Furue M, Moroi Y: Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma. J Cutan Pathol; 2008 Aug;35(8):722-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma.
  • BACKGROUND: Activating transcription factor-2/Activator protein-1 (AP-1), Signal transducer and activator of transcription-3 and p53 are important regulators of cellular proliferation, apoptosis, differentiation in the pathogenesis of many human tumors, but the expression of phosphorylated (p)-activating transcription factor-2 (p-ATF2), phosphorylated (p)-signal transducer and activator of transcription-3 (p-STAT3) and p53 family (p63 and p73) has not been investigated in cutaneous angiosarcoma (CAS) and pyogenic granuloma (PG) so far.
  • OBJECTIVES: To investigate the expression of p-ATF2, p-STAT3 and p53 and its family in cutaneous vascular tumors (CAS and PG).
  • The p-ATF2-, p-STAT3- and p53 expression (% positive cells) in CAS and PG were significantly higher than in normal dermal vessels, but none of these transcription factors distinguished malignant (CAS)- from benign (PG) vascular tumor.
  • CONCLUSIONS: The present study suggests that overexpression of p-ATF2, p-STAT3 and possibly p53, but not p63 or p73, may contribute to the tumorigenesis of cutaneous vascular tumors.
  • [MeSH-major] Activating Transcription Factor 2 / biosynthesis. Gene Expression Regulation, Neoplastic. Granuloma, Pyogenic / metabolism. Hemangiosarcoma / metabolism. STAT3 Transcription Factor / biosynthesis. Skin Neoplasms / metabolism. Tumor Suppressor Protein p53 / biosynthesis


13. Rader C, Piorkowski J, Bass DM, Babigian A: Epulis gravidarum manum: pyogenic granuloma of the hand occurring in pregnant women. J Hand Surg Am; 2008 Feb;33(2):263-5
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  • Pyogenic granuloma, also known as lobular capillary hemangioma, is a benign vascular tumor of the skin and mucous membranes.
  • We propose the term epulis gravidarum manum to describe this skin lesion.
  • [MeSH-major] Granuloma, Pyogenic / pathology. Hand / pathology. Pregnancy Complications / pathology. Skin Diseases / pathology

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  • (PMID = 18294552.001).
  • [ISSN] 0363-5023
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Lucas DR: Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion. Arch Pathol Lab Med; 2009 Nov;133(11):1804-9
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  • [Title] Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion.
  • Most are sporadic, presenting as cutaneous tumors in the scalp/face of elderly patients.
  • Radiation-associated angiosarcoma typically presents as a cutaneous tumor several years posttherapy.
  • Atypical vascular lesion refers to a small, usually lymphatic-type vascular proliferation in radiated skin.
  • Although most atypical vascular lesions pursue a benign course, they recur and very rarely progress to angiosarcoma.
  • Distinguishing this lesion from well-differentiated angiosarcoma in a biopsy can be challenging, especially because areas indistinguishable from atypical vascular lesion are found adjacent to angiosarcoma.
  • Recently, vascular-type atypical vascular lesion, which resembles hemangioma, has been described, thus expanding the definition of this entity.
  • [MeSH-major] Hemangioma / pathology. Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology. Skin Neoplasms / pathology. Vascular Diseases / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Breast Neoplasms / radiotherapy. Female. Humans. Skin / blood supply

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  • (PMID = 19886715.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 12
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15. Tatsas AD, Keedy VL, Florell SR, Simpson JF, Coffin CM, Kelley MC, Cates JM: Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma. J Cutan Pathol; 2010 Aug;37(8):901-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma.
  • Cutaneous angiosarcoma can sometimes mimic other benign and malignant lesions, thereby presenting a difficult differential diagnosis.
  • In the two cases of cutaneous angiosarcoma presented herein, extensive foamy cell alteration of tumor cells resembled a reactive xanthogranulomatous process.
  • Foamy cell angiosarcoma is an unusual and deceptively benign morphologic variant of cutaneous angiosarcoma.
  • Critical features for diagnosis include the presence of a deep, permeative, sometimes 'scaffolding' growth pattern and subtle areas of vascular formation.
  • [MeSH-major] Foam Cells / pathology. Granuloma / pathology. Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology

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  • (PMID = 20175826.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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16. Káram-Orantes M, Fonte-Avalos V, Zuloaga-Salcedo S, Domínguez-Cherit J: [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006]. Gac Med Mex; 2007 Sep-Oct;143(5):371-5
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  • [Title] [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006].
  • BACKGROUND: Benign skin neoplasms are defined as autonomous growing tissue unrelated to normal growing of the skin, that persist even after the originating stimulus dissapears.
  • Almost all human beings have a certain number of benign cutaneous neoplasms and many never seek medical attention.
  • The aim of this study was to record the number of benign tumors studied at the Dermatology Department of a medical facility.
  • We included year of admission, number of biopsies, sex, age, tumor location, histological and clinical diagnoses.
  • RESULTS: We analyzed 9,436 biopsies of which 3,765 constituted benign neoplasms; 595 were not included and our total sample was 3,170 tumors.
  • The most frequent tumors according to histopathological diagnoses in descending order were: melanocytic, cutaneous cysts, fibrous tumors, vascular tumors, epidermal tumors, fat tumors, tumors with hair differentiation, neural tumors, glandular tumors, tumors with sebaceous differentiation, cartilage and bone tumors, and smooth muscle tumors.
  • The most common benign tumors were: Melanocytic nevi, epidermal cysts, seborrheic keratoses, pyogenic granulomas, lipomas and dermatofibromas.
  • CONCLUSIONS: Melanocytes represented by melanocytic nevi (junctional, intradermic and compound) were the most frequent benign neoplasms, followed by epidermoid cysts.
  • Our results illustrate the most common benign tumors observed in a dermatology department.

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  • (PMID = 18246930.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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17. Pascual-Castroviejo I, Pascual-Pascual SI, Velazquez-Fragua R, García-Guereta L, López-Gutiérrez JC, Olivares P, Tovar J: Association of cutaneous red-to-purple hemangiomas with leptomeningeal hemangiomas. a clinical study of two patients. Neuropediatrics; 2010 Feb;41(1):7-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of cutaneous red-to-purple hemangiomas with leptomeningeal hemangiomas. a clinical study of two patients.
  • Cutaneous hemangioma is a benign vascular tumor of infancy with an initial proliferating period that appears between 1 to 2 weeks of life, extends during 18 months to 2 years of life, and then slowly regresses during several years until it disappears completely.
  • Vascular malformations are present at birth, grow commensurately with the child, and are characterized histologically by a normal rate of endothelial cell turnover, flat endothelium, thin (normal) basal membrane and normal mast cells.
  • These cutaneous anomalies are commonly associated with cerebellar malformations, main cerebral arteries anomalies, congenital cardiac anomalies and/or coarctation of the aorta and persistence of embryonic arteries.
  • Cutaneous hemangiomas can be associated with intracranial or extracranial hemangiomas that regress at the same time as the cutaneous hemangiomas.
  • Cutaneous hemangiomas may show different types of color.
  • Cutaneous red-to-purple hemangiomas are uncommon and their bright-red color is evident from the first weeks of life and remains unaltered until the hemangioma disappears.
  • Involution of the cutaneous and leptomeningeal hemangiomas seems to occur simultaneously as in other types of external and internal hemangiomas.
  • [MeSH-major] Hemangioma. Meningeal Neoplasms. Skin Diseases, Vascular. Skin Neoplasms

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  • (PMID = 20571984.001).
  • [ISSN] 1439-1899
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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18. Brown JA, Morgan MB: Pedunculated hemangiopericytoma-like tumor: peculiar fibroepithelial polyp or fibrous histiocytoma variant. J Cutan Pathol; 2008 Aug;35(8):748-51
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  • [Title] Pedunculated hemangiopericytoma-like tumor: peculiar fibroepithelial polyp or fibrous histiocytoma variant.
  • Apropos of this concern, we present a series of three cutaneous polypoid lesions that simulated fibroepithelial polyp, yet upon close scrutiny yielded histologic features of solitary fibrous tumor (SFT) or hemangiopericytoma.
  • These pedunculated lesions showed a storiform pattern of spindled cells with interspersed gaping vascular channels reminiscent of SFT or hemangiopericytoma.
  • [MeSH-major] Hemangiopericytoma / pathology. Histiocytoma, Benign Fibrous / pathology. Polyps / pathology. Skin Neoplasms / pathology

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  • (PMID = 18422978.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2; EC 2.3.2.13 / Factor XIIIa
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19. Herron MD, Coffin CM, Vanderhooft SL: Vascular stains and hair collar sign associated with congenital anomalies of the scalp. Pediatr Dermatol; 2005 May-Jun;22(3):200-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vascular stains and hair collar sign associated with congenital anomalies of the scalp.
  • We reported a series of three meningothelial hamartomas, one benign fibrous tumor, and one aplasia cutis congenita presenting with the hair collar sign and a coexistent vascular stain.
  • Our series highlighted the importance of coexisting cutaneous markers found in the newborn period.
  • The presence of a vascular stain and hair collar sign with or without a congenital scalp nodule should increase suspicion of an associated cranial dysraphism.

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  • (PMID = 15916564.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Plaza JA, Morrison C, Magro CM: Assessment of TCR-beta clonality in a diverse group of cutaneous T-Cell infiltrates. J Cutan Pathol; 2008 Apr;35(4):358-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of TCR-beta clonality in a diverse group of cutaneous T-Cell infiltrates.
  • While some unequivocally benign infiltrates are easy to distinguish from cutaneous T-cell lymphoma (CTCL), drug-associated lymphomatoid hypersensitivity reaction and cutaneous lesions of collagen vascular disease can show cytologic atypia, clonality and an immunophenotypic profile that closely simulates CTCL and cause diagnostics difficulties.
  • Similar immunophenotypic and molecular abnormalities to those of malignant lymphoma can also be observed in pityriasis lichenoides chronica (PLC), large plaque parapsoriasis (LPP), pigmented purpuric dermatosis (PPD) and atypical lymphocytic lobular panniculitis leading one to consider these entities as forms of cutaneous lymphoid dyscrasia.
  • The purpose of our study was to evaluate the distinction of these various subcategories of cutaneous T-cell infiltrates by assessment of T-cell receptor (TCR)-beta gene rearrangement.
  • Formalin-fixed paraffin-embedded skin biopsies from 80 patients containing a T-cell dominant lymphocytic infiltrate were analyzed for TCR-beta gene rearrangement.
  • However, some cases of drug associated lymphomatoid hypersensitivity, collagen vascular disease and the various cutaneous lymphoid dyscrasias (i.e.
  • [MeSH-major] Gene Rearrangement, beta-Chain T-Cell Antigen Receptor / genetics. Genes, T-Cell Receptor / genetics. Leukemic Infiltration. Lymphoma, T-Cell, Cutaneous / genetics
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Clone Cells. Humans. Lymphocytes / pathology. Panniculitis / genetics. Panniculitis / metabolism. Panniculitis / pathology. Parapsoriasis / genetics. Parapsoriasis / metabolism. Parapsoriasis / pathology. Pigmentation Disorders. Pityriasis Lichenoides / genetics. Pityriasis Lichenoides / metabolism. Pityriasis Lichenoides / pathology. Purpura / genetics. Purpura / metabolism. Purpura / pathology

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  • (PMID = 17976210.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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21. Schrecengost JE, Tabbara S, Patterson J, Wick MR: Cutaneous mesenchymal hamartoma with mixed myogenous differentiation. J Cutan Pathol; 2006 Apr;33(4):327-30
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  • [Title] Cutaneous mesenchymal hamartoma with mixed myogenous differentiation.
  • Collagen and vascular changes were also apparent.
  • They must be distinguished from a variety of other tumors, including juvenile rhabdomyoma, benign Triton tumor, and rhabdomyosarcoma.
  • [MeSH-major] Cell Differentiation. Dermis / pathology. Hamartoma / diagnosis. Mesoderm / pathology. Skin Neoplasms / diagnosis

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  • (PMID = 16630187.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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22. Pisacane AM, Risio M: VEGF and VEGFR-2 immunohistochemistry in human melanocytic naevi and cutaneous melanomas. Melanoma Res; 2005 Feb;15(1):39-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] VEGF and VEGFR-2 immunohistochemistry in human melanocytic naevi and cutaneous melanomas.
  • Vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor-2 (VEGFR-2) play a key role in vasculogenesis and angiogenic sprouting, which are crucial for tumour development and metastasis.
  • In order to determine their possible role in the acquisition of metastatic potential throughout melanocytic tumour progression, VEGF and VEGFR-2 immunohistochemical expression were evaluated in 36 human melanocytic tumours of the skin (24 malignant melanomas and 12 common naevi).
  • Taken together, these data indicate that VEGF production is a common event in benign melanocytic tumours, whereas VEGFR-2 expression, co-localized in the cytoplasmic and nuclear membrane, is associated with progression towards invasive melanoma.
  • The role exerted by VEGF/VEGFR-2, however, seems to be independent of the development of a tumour-related capillary network.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Melanoma / metabolism. Nevus, Pigmented / metabolism. Skin Neoplasms / metabolism. Vascular Endothelial Growth Factor A / metabolism. Vascular Endothelial Growth Factor Receptor-2 / metabolism
  • [MeSH-minor] Cell Nucleus / metabolism. Cell Nucleus / pathology. Cytoplasm / metabolism. Cytoplasm / pathology. Humans. Immunoenzyme Techniques. Neoplasm Invasiveness

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  • (PMID = 15714119.001).
  • [ISSN] 0960-8931
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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23. Cohn ML, Goncharuk VN, Diwan AH, Zhang PS, Shen SS, Prieto VG: Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms. J Cutan Pathol; 2005 Sep;32(8):533-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms.
  • It is unknown whether claudins play a role in cutaneous melanoma.
  • Immunohistochemical studies were performed on tissue microarrays containing 19 benign melanocytic nevi (BN), 21 dysplastic nevi (DN), 23 primary malignant melanomas (MMs), and 31 metastatic melanomas (MMMs) using a polyclonal anti-claudin-1 antibody.
  • Immunoreactivity in tumor cells and associated vessels was graded by intensity and by percentage of reactive cells.
  • Tumor-associated vessels showed the following results: 11 of 19 (58%) in BN, 14 of 21 (67%) in DN, 17 of 23 (74%) in MM, and 6 of 31 (19%) in MMM.
  • A significant loss of expression was noted between MMM and all other lesions in tumor cells and associated vessels.
  • Within primary melanomas, there was a significant correlation between expression of claudin in tumor cells and Clark level/Breslow thickness.
  • Also significant was a decreased expression of claudin in tumor vessels of lesions with higher Breslow thickness or Clark level.
  • These data suggest that loss of claudin-1 may play a significant role in the acquisition of metastatic phenotype in cutaneous melanoma.
  • Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms.
  • [MeSH-major] Dysplastic Nevus Syndrome / metabolism. Melanoma / metabolism. Membrane Proteins / metabolism. Nevus, Pigmented / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Blood Vessels / metabolism. Blood Vessels / pathology. Claudin-1. Endothelium, Vascular / metabolism. Endothelium, Vascular / pathology. Fluorescent Antibody Technique, Indirect. Humans. Immunoenzyme Techniques. Neoplasm Metastasis. Phenotype. Protein Array Analysis

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  • (PMID = 16115050.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CLDN1 protein, human; 0 / Claudin-1; 0 / Membrane Proteins
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24. Requena L, Luis Díaz J, Manzarbeitia F, Carrillo R, Fernández-Herrera J, Kutzner H: Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases. J Cutan Pathol; 2008 Feb;35(2):225-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases.
  • The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas).
  • The latter is a vascular neoplasm showing varying combinations of benign, low-grade malignant and malignant vascular components.
  • The neoplasm showed a more aggressive behavior than other reported cases of composite hemangioendothelioma and it developed satellitosis and metastases to the inguinal lymph nodes.
  • [MeSH-major] Foot Diseases / pathology. Hemangioendothelioma / pathology. Leg / pathology. Lymphatic Metastasis / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Homeodomain Proteins / metabolism. Humans. Immunohistochemistry. Male. Middle Aged. Tumor Suppressor Proteins / metabolism

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  • (PMID = 18190450.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Tumor Suppressor Proteins; 0 / prospero-related homeobox 1 protein
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25. Ghazali N, Cascarini L, Norris P, Barrett AW, Lavery KM: Perivascular epithelioid cell tumor (PEComa) of the cheek. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jul;110(1):e26-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perivascular epithelioid cell tumor (PEComa) of the cheek.
  • We present the unusual case of a perivascular epithelioid cell tumor (PEComa) occurring within the cheek of a 32-year-old woman.
  • It mainly affects the abdominopelvic region and rarely occurs in somatic soft tissue or skin.
  • To our knowledge, this is the first reported case of PEComa occurring in the facial cutaneous tissues.
  • Other possible diagnoses considered included benign mesenchymal tumors of smooth muscle or neural origin.
  • The tumor was completely excised, but in view of uncertainty as to how this entity would behave in an unusual location, lifelong follow up is recommended.
  • [MeSH-minor] Actins / analysis. Adult. Antigens, Neoplasm / analysis. Arterioles / pathology. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Follow-Up Studies. Humans. MART-1 Antigen. Muscle, Smooth, Vascular / pathology. Neoplasm Proteins / analysis

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20610292.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins
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26. Urquhart JL, Uzieblo A, Kohler S: Detection of HHV-8 in pyogenic granuloma-like Kaposi sarcoma. Am J Dermatopathol; 2006 Aug;28(4):317-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Kaposi sarcoma (KS) is a low-grade vascular neoplasm associated with human herpesvirus-8 (HHV-8) infection.
  • Recently, we encountered 6 KS tumors that histologically mimicked pyogenic granuloma (PG), a common benign vascular tumor of the skin that usually does not figure in the histologic differential diagnosis of KS.

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  • (PMID = 16871034.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Viral; 0 / Nuclear Proteins; 0 / Phosphoproteins; 0 / latent nuclear antigen (LNA)
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27. Lee HW, Han SS, Kang J, Lee MW, Choi JH, Moon KC, Koh JK: Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor? J Cutan Pathol; 2006 Apr;33(4):323-6
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  • [Title] Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor?
  • Eccrine angiomatous hamartoma (EAH) is a rare, benign condition characterized histologically by increased numbers of eccrine elements, as well as numerous capillary channels.
  • We report a 35-year-old female patient with multiple, sudoriparous, subcutaneous nodules on the right foot, which showed typical histopathological findings of EAH, and vascular components of the tumor consisted of thin-walled dilated vascular spaces intermixed with spindle cells and some histiocytoid endothelial cells representing spindle cell hemangioma (SCH).

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  • (PMID = 16630186.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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28. Piedra MP, Scheithauer BW, Driscoll CL, Link MJ: Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report. Neurosurgery; 2006 Jul;59(1):E206; discussion E206
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report.
  • OBJECTIVE: The majority of tumors of the cerebellopontine angle (CPA) are benign.
  • A neurological work-up revealed a large tumor in the left CPA radiographically diagnosed as a vestibular schwannoma.
  • INTERVENTION: A translabyrinthine approach revealed a pigmented, vascular neoplasm encasing vessels and cranial nerves of the left CPA.
  • The tumor was subtotally resected, and a histopathological diagnosis of melanoma was made.
  • The patient had no history of cutaneous melanoma and no other site of disease was ever discovered.

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  • (PMID = 16823290.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Kim J, McNiff JM: Keloidal atypical fibroxanthoma: a case series. J Cutan Pathol; 2009 May;36(5):535-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although AFX is a pleomorphic cutaneous tumor typically associated with a good prognosis, occasional reports of metastatic AFX highlight the importance of accurate identification.
  • In several cases, the keloidal collagen also formed ring-shaped structures surrounding CD31-positive vascular structures.
  • CONCLUSIONS: The diagnosis of keloidal AFX requires the exclusion of other malignant and benign lesions with keloidal or sclerotic collagen.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Keloid / pathology

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  • (PMID = 19476521.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD31; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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30. Tardío JC: CD34-reactive tumors of the skin. An updated review of an ever-growing list of lesions. J Cutan Pathol; 2008 Dec;35(12):1079-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD34-reactive tumors of the skin. An updated review of an ever-growing list of lesions.
  • Over the past few years, a growing number of cutaneous tumors expressing CD34 is being reported.
  • The list contains benign and malignant neoplasms as well as reactive and hamartomatous lesions of diverse lineages of differentiation, including fibroblastic, myofibroblastic, fibrohistiocytic, vascular, neural, adipocytic, smooth muscle, hematopoietic, melanocytic and epithelial.
  • In part, this is because of the fact that in this area are, aside to well-defined entities, histologically and clinically diverse, recently reported cutaneous CD34-reactive lesions, whose definitions, limits and relationships are not completely established.
  • The CD34 expression plays a key role in the differential diagnosis of some tumors, such as dermatofibrosarcoma protuberans, epithelioid sarcoma (ES) or pleomorphic hyalinizing angiectatic tumor of soft parts, with important therapeutic consequences.
  • However, in all of them, the knowledge of the immunohistochemical profile contributes to our understanding of the cutaneous pathology.
  • [MeSH-major] Antigens, CD34 / immunology. Biomarkers, Tumor. Skin Neoplasms / immunology. Skin Neoplasms / pathology
  • [MeSH-minor] Cell Lineage. Dermatofibrosarcoma / diagnosis. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Epidermodysplasia Verruciformis / diagnosis. Epidermodysplasia Verruciformis / pathology. Humans. Integumentary System / pathology. Sarcoma / diagnosis. Sarcoma / pathology. Skin / immunology. Skin / pathology

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  • [RepublishedIn] J Cutan Pathol. 2009 Jan;36(1):89-102 [19125742.001]
  • (PMID = 18976402.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor
  • [Number-of-references] 171
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31. Inoue T, Sada A, Mori T, Misago N, Narisawa Y: Congenital myofibroma of the skin mimicking a piloleiomyoma. J Cutan Pathol; 2010 Jun;37(6):678-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital myofibroma of the skin mimicking a piloleiomyoma.
  • Myofibroma is an uncommon benign soft tissue disorder, which is usually congenital or present in early infancy.
  • The other area contains either round or polygonal cells with slightly pleomorphic, hyperchromatic nuclei or small spindle cells typically arranged around a distinct hemangiopericytoma-like vascular pattern.
  • In the present case, the majority of the tumor was composed of the plump myoid spindle cells.
  • However, the tumor cells were not immunohistochemically positive for desmin.
  • Moreover, careful examination revealed a hemangiopericytoma-like vascular pattern characterized by the presence of high cellular areas with irregular vascular spaces.
  • [MeSH-major] Leiomyoma / pathology. Myofibroma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Desmin / metabolism. Diagnosis, Differential. Female. Humans. Infant. Skin / metabolism. Skin / pathology

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  • (PMID = 20522159.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Desmin
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32. Tardío JC: CD34-reactive tumors of the skin. An updated review of an ever-growing list of lesions. J Cutan Pathol; 2009 Jan;36(1):89-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD34-reactive tumors of the skin. An updated review of an ever-growing list of lesions.
  • Over the past few years, a growing number of cutaneous tumors expressing CD34 is being reported.
  • The list contains benign and malignant neoplasms as well as reactive and hamartomatous lesions of diverse lineages of differentiation, including fibroblastic, myofibroblastic, fibrohistiocytic, vascular, neural, adipocytic, smooth muscle, hematopoietic, melanocytic and epithelial.
  • In part, this is because of the fact that in this area are, aside to well-defined entities, histologically and clinically diverse, recently reported cutaneous CD34-reactive lesions, whose definitions, limits and relationships are not completely established.
  • The CD34 expression plays a key role in the differential diagnosis of some tumors, such as dermatofibrosarcoma protuberans, epithelioid sarcoma or pleomorphic hyalinizing angiectatic tumor of soft parts, with important therapeutic consequences.
  • However, in all of them, the knowledge of the immunohistochemical profile contributes to our understanding of the cutaneous pathology.
  • [MeSH-major] Antigens, CD34 / metabolism. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

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  • [RepublishedFrom] J Cutan Pathol. 2008 Dec;35(12):1079-92 [18976402.001]
  • (PMID = 19125742.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Corrected and Republished Article; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34
  • [Number-of-references] 171
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33. Mederle O, Mederle N, Bocan EV, Ceauşu R, Raica M: VEGF expression in dog mastocytoma. Rev Med Chir Soc Med Nat Iasi; 2010 Jan-Mar;114(1):185-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The biologic behavior of mastocytomas is highly variable; some tumors have a benign behavior, whereas others exhibit aggressive growth and metastasis.
  • Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis and a potential autocrine growth factor for neoplastic cells in various malignancies.
  • MATERIAL AND METHOD: In the present study, we have investigated expression of VEGF in cutaneous tumor from a dog and combined immunohistochemical expression of VEGF with mast cell tryptase, CD117 and vimentin.
  • RESULTS: Tumor cells were positive for VEGF, and inflammatory cells were negative.
  • VEGF expression was found in tumor cells as a heterogeneous positive reaction, with cytoplasmic pattern and moderate to strong in intensity.
  • Arrangement of tumor cells was in clusters, in deepest part, close to the proliferation front.
  • The dog died 5 month from the diagnosis, and our observation suggest that VEGF secretion by tumor cells correlates with unfavorable prognosis.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Dog Diseases / metabolism. Mastocytoma / veterinary. Skin Neoplasms / veterinary. Vascular Endothelial Growth Factor A / metabolism

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  • (PMID = 20509299.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor A; 0 / Vimentin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 3.4.21.59 / Tryptases
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34. Sheehan M, Roumpf SO, Summerlin DJ, Billings SD: Spindle cell hemangioma: report of a case presenting in the oral cavity. J Cutan Pathol; 2007 Oct;34(10):797-800
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Spindle cell hemangioma, formerly termed spindle cell hemangioendothelioma, is an uncommon benign vascular tumor.
  • RESULTS: The tumor was a well-circumscribed vascular proliferation of spindled to epithelioid endothelial cells.
  • Tumor cells with intracytoplasmic vascular lumens were present in several areas.
  • The tumor was positive for CD31 and CD34.
  • CONCLUSIONS: Spindle cell hemangioma rarely presents in the oral cavity and needs to be considered in the differential diagnosis of oral cavity vascular tumors to avoid misdiagnosis as a more aggressive vascular tumor.
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiosarcoma / diagnosis. Humans. Male. Sarcoma, Kaposi / diagnosis. Treatment Outcome

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  • (PMID = 17880587.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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35. Luzar B, Calonje E: Morphological and immunohistochemical characteristics of atypical fibroxanthoma with a special emphasis on potential diagnostic pitfalls: a review. J Cutan Pathol; 2010 Mar;37(3):301-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIAL AND METHODS: Histological features analyzed in 66 AFXs were: ulceration, morphological variants, growth pattern, location in the skin and vascular/perineural invasion.
  • All developed on sun damaged skin.
  • No vascular/perineural invasion was seen.
  • This study expands the spectrum of non-vascular CD31 positive tumors.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Arm / pathology. Biomarkers, Tumor. Diagnosis, Differential. Female. Fibrosis / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Scalp / pathology. Sex Factors

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  • [CommentIn] J Cutan Pathol. 2011 Aug;38(8):679-80 [21518383.001]
  • [CommentIn] J Cutan Pathol. 2010 Mar;37(3):299-300 [20458783.001]
  • (PMID = 19807823.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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36. Volmar KE, Cummings TJ, Wang WH, Creager AJ, Tyler DS, Xie HB: Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Arch Pathol Lab Med; 2005 May;129(5):e113-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma.
  • Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma.
  • Knowing the cytologic features of primary skin adnexal neoplasms helps distinguish them from cutaneous metastases, which are more commonly referred for fine-needle aspiration biopsy evaluation.
  • We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease.
  • [MeSH-minor] Axilla. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Lymph Nodes / pathology. Lymph Nodes / surgery. Male. Middle Aged. Mitotic Index. Neoplasm Metastasis / diagnosis. Treatment Outcome

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  • (PMID = 15859654.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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37. Murali R, Palfreeman S: Clear cell atypical fibroxanthoma - report of a case with review of the literature. J Cutan Pathol; 2006 May;33(5):343-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Clear cell atypical fibroxanthoma (CCAFX) is a rare variant of atypical fibroxanthoma (AFX), a pleomorphic dermal tumour associated with a good prognosis.
  • Sections showed an ulcerated nodule composed of pleomorphic spindled and polygonal cells with clear cytoplasm, invested by a delicate vascular stroma, reminiscent of clear cell renal cell carcinoma.
  • The tumour cells stained with vimentin, CD68 and CD99 and were cytokeratin-negative.
  • The diagnosis of CCAFX requires the exclusion of other pleomorphic clear cell tumours that can occur in the skin by using a combination of morphology, immunohistochemistry and electronmicroscopy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Ear / pathology. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission

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  • (PMID = 16640540.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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38. Papadopoulos VG, Kourea HP, Adonakis GL, Decavalas GO: A case of umbilical cord hemangioma: Doppler studies and review of the literature. Eur J Obstet Gynecol Reprod Biol; 2009 May;144(1):8-14
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  • Hemangiomas of the umbilical cord are extremely rare benign vascular tumors, not always detected prenatally.
  • We report a case of an antenatally detected umbilical cord hemangioma with one artery crossing the tumor, and we reviewed the literature.
  • Association with cutaneous vascular malformations, and single umbilical artery were assessed.
  • [MeSH-major] Hemangioma / ultrasonography. Umbilical Cord. Vascular Neoplasms / ultrasonography

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  • (PMID = 19251351.001).
  • [ISSN] 1872-7654
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
  • [Number-of-references] 39
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39. Salazard B, Philandrianos C: [Children's tumors of the hand]. Chir Main; 2008 Dec;27 Suppl 1:S185-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangioma is the most common soft-tissue tumor in infancy and childhood.
  • Other vascular abnormalities are capillary malformation, venous malformation.
  • Many other benign soft-tissue and cutaneous tumors can be seen (ganglion cyst, naevus, fibroma...).
  • [MeSH-major] Bone Neoplasms. Fibroma. Hand. Nevus. Skin Neoplasms
  • [MeSH-minor] Adolescent. Age Factors. Child. Child, Preschool. Diagnosis, Differential. Female. Hamartoma / congenital. Hamartoma / diagnosis. Humans. Infant. Infant, Newborn. Male. Neoplasms, Vascular Tissue / diagnosis. Neoplasms, Vascular Tissue / epidemiology. Nevus, Pigmented / diagnosis. Nevus, Pigmented / epidemiology. Nevus, Pigmented / surgery. Skin Transplantation

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  • (PMID = 18848496.001).
  • [ISSN] 1297-3203
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 12
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40. Trindade F, Haro R, Requena L: Giant angiolymphoid hyperplasia with eosinophilia on the chest. J Cutan Pathol; 2009 Apr;36(4):493-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiolymphoid hyperplasia with eosinophilia is a rare vascular proliferation characterized by single or multiple purplish, brownish papules and subcutaneous nodules, sometimes associated with pain or pruritus.
  • This rare benign process occurs with a female predominance.
  • Approximately 85% of the lesions occur in the skin of the head and neck; most of them are around the ear or on the forehead or scalp.
  • Whether angiolymphoid hyperplasia with eosinophilia represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, the etiology remains unclear.
  • The lesion is benign but may be persistent and is difficult to eradicate.
  • We report on a case of a 58-year-old Caucasian man who presented a purplish pink dome-shaped tumor of size up to 8 cm in diameter located on the chest.

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  • (PMID = 19278439.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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41. Laga AC, Tajirian AL, Islam MN, Bhattacharyya I, Cohen DM, Plamondon CJ, Robinson-Bostom L: Myopericytoma: report of two cases associated with trauma. J Cutan Pathol; 2008 Sep;35(9):866-70
MedlinePlus Health Information. consumer health - Wounds and Injuries.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myopericytoma is a rare, recently described tumor demonstrating a hemangiopericytoma-like vascular pattern.
  • Despite sharing morphologic features with angioleiomyoma, myofibroma and glomus tumor, myopericytoma is thought to represent a distinct perivascular myoid neoplasm of skin and soft tissues.
  • The tumor is characterized by a radial and perivascular arrangement of ovoid, spindled to round neoplastic cells that are immunoreactive to alpha-smooth muscle actin, often for h-caldesmon as well as smooth muscle myosin-heavy chain, and usually negative for desmin antibodies.
  • Most cases of myopericytoma are benign, however, local recurrence and malignancy have recently been reported, Myopericytoma can be multifocal involving a single or multiple anatomic regions, and tends to occur in dermal and superficial soft tissues of adults primarily on the extremities.
  • [MeSH-major] Hemangiopericytoma / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology. Wounds and Injuries / complications
  • [MeSH-minor] Actins / metabolism. Aged. Biomarkers, Tumor / metabolism. Calcium-Binding Proteins / metabolism. Female. Humans. Male. Microfilament Proteins / metabolism. Middle Aged. Mouth Mucosa / injuries. Myosin Heavy Chains / metabolism. Nose / injuries. Treatment Outcome

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  • (PMID = 18494828.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Microfilament Proteins; 0 / calponin; EC 3.6.4.1 / Myosin Heavy Chains
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42. Paik AS, Lee PH, O'Grady TC: Acquired progressive lymphangioma in an HIV-positive patient. J Cutan Pathol; 2007 Nov;34(11):882-5
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acquired progressive lymphangioma (APL) is a rare condition characterized by benign proliferation of thin-walled vessels lined by flattened endothelial cells.(1-4) Although benign, the acquired nature of this tumor may lead to misdiagnosis as a malignant vascular tumor.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / complications. Lymphangioma / complications. Lymphangioma / pathology. Skin Neoplasms / complications. Skin Neoplasms / pathology


43. Sabattini S, Bettini G: An immunohistochemical analysis of canine haemangioma and haemangiosarcoma. J Comp Pathol; 2009 Feb-Apr;140(2-3):158-68
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Forty samples of canine cutaneous and visceral haemangiosarcoma (HSA), 29 samples of cutaneous and visceral haemangioma (HA) and 10 control samples of granulation tissue (GT) were labelled with antisera specific for vimentin, smooth muscle actin, von Willebrand factor (vWF), CD117 (KIT), vascular endothelial growth factor receptor-3 (VEGFR-3), vascular endothelial growth factor-C (VEGFC) and CD44.
  • Further antisera were employed to determine the level of cellular proliferation (MIB-1 index) and toluidine blue staining was used to detect populations of tumour-infiltrating mast cells (MCs).
  • Marked infiltration of MC was detected in HA, suggesting a possible role for these cells in the pathogenesis of benign vascular neoplasia in the dog.
  • [MeSH-minor] Animals. Biomarkers, Tumor / metabolism. Dogs. Immunohistochemistry. Mast Cells / cytology

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  • (PMID = 19091326.001).
  • [ISSN] 1532-3129
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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44. Carvalho L, Lipay M, Belfort F, Santos I, Andrade J, Haddad A, Brunstein F, Ferreira L: Telomerase activity in prognostic histopathologic features of melanoma. J Plast Reconstr Aesthet Surg; 2006;59(9):961-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • One hundred and eight samples were distributed in four histological groups: 30 samples from primary cutaneous melanomas, 24 from peritumoural skin sites, 28 from benign melanocytic lesions, and 26 from normal skin sites as a control.
  • RESULTS: TA was different among the four tested groups (Kruskall-Wallis test p<0.001), and increasing values of TA were observed progressing from normal skin to benign and then to malignant lesions.
  • Among melanoma samples, there was a significant association between TA and ulceration (p=0.025), TA and vascular invasion (p=0.018) and TA and mitotic rate (p=0.029) (Mann-Whitney test).
  • CONCLUSIONS: We observed that TA had increased from control skin to peritumoural skin, and then to benign melanocytic lesions and finally to melanoma, suggesting tumour progression.
  • TA showed higher values in the presence of some important histopathologic parameters related to poor prognosis in cutaneous melanoma such as ulceration, vascular invasion, satellites, high rates of mitosis, and in thicker tumours.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Melanoma / diagnosis. Skin Neoplasms / diagnosis. Telomerase / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Disease Progression. Enzyme-Linked Immunosorbent Assay / methods. Female. Humans. Male. Middle Aged. Nevus, Pigmented / diagnosis. Polymerase Chain Reaction / methods. Prognosis. Skin / enzymology

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  • (PMID = 16920589.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.7.49 / Telomerase
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45. Singh AD, Kaiser PK, Sears JE: Choroidal hemangioma. Ophthalmol Clin North Am; 2005 Mar;18(1):151-61, ix
MedlinePlus Health Information. consumer health - Birthmarks.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be circumscribed or diffuse.
  • Diffuse choroidal hemangiomas are usually evident at birth and generally occur as a part of neuro-oculo-cutaneous hemangiomatosis (Sturge-Weber syndrome).

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  • (PMID = 15763200.001).
  • [ISSN] 0896-1549
  • [Journal-full-title] Ophthalmology clinics of North America
  • [ISO-abbreviation] Ophthalmol Clin North Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 55
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46. Kreusel KM: Ophthalmological manifestations in VHL and NF 1: pathological and diagnostic implications. Fam Cancer; 2005;4(1):43-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Capillary retinal angioma, a benign vascular tumor, is the classical ocular lesion in VHL.
  • Extension of the tumor beyond the chiasm worsens the prognosis quoad vitam.
  • The hallmark of NF 1, namely cutaneous neurofibroma can cause visual impairment when affecting the skin of the eyelids.

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  • (PMID = 15883709.001).
  • [ISSN] 1389-9600
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 63
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47. Goh SG, Dayrit JF, Calonje E: Sarcomatoid eccrine porocarcinoma: report of two cases and a review of the literature. J Cutan Pathol; 2007 Jan;34(1):55-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present two cases of sarcomatoid eccrine porocarcinoma associated with a benign poroma.
  • Case 1 pertained to an 82-year-old woman with an ulcerated chest wall tumor, and Case 2 was that of a 74-year-old woman who presented with an ulcerated plaque in the lower leg.
  • Case 1 showed an unusual pseudo-angiosarcomatous morphology with spindle cells dissecting through collagen bundles and forming vascular like channels.
  • In both the cases, benign poromatous elements were histologically evident.

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  • (PMID = 17214856.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Actins; 0 / Carcinoembryonic Antigen; 0 / Mucin-1; 68238-35-7 / Keratins
  • [Number-of-references] 31
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48. Zheng JW, Wang YA, Zhou GY, Zhu HG, Ye WM, Zhang ZY: [Head and neck hemangiomas: how and when to treat]. Shanghai Kou Qiang Yi Xue; 2007 Aug;16(4):337-42
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangiomas are common benign vascular tumors of infancy characterized by a proliferative growth phase followed by very slow inevitable regression (involutive phase) between one to ten years of age, about 60% to 70% of the lesions are found in the head and neck region.
  • The argon laser (514 nm in wavelength, 0.5 mm in depth) is useful in the treatment of superficial telangiectasias and small, flat cutaneous hemangiomas.
  • Flashlamp-pumped pulsed-dye laser (FPDL, 585 nm or 595 nm in wavelength, 1.0-2.0 mm in depth) can be used in patients with cutaneous and flat hemangiomas at the sites of potential functional impairment.
  • For larger and deeper hemangiomas up to a depth of 2.0 cm, percutaneous interstitial Nd:YAG laser treatment may be preferred, because it may decrease possible cutaneous skin damage and more effectively reduce bulky, deep lesion. (5) Topical application of imiquimoid and intratumoral injection of steroids or bleomycin can be used in selected patients with rapidly growing hemangioma. (6) The indication for a primary operation is rare and limited to large hemangiomas in the eyelid or hemangiomas on the scalp.
  • A successful treatment of hemangiomas should be individualized and based on the size of the tumor, the localization, and the therapies available.

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  • (PMID = 17924011.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] China
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