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1. Cardona DM, Knapik JA, Reith JD: Dedifferentiated parosteal osteosarcoma with giant cell tumor component. Skeletal Radiol; 2008 Apr;37(4):367-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dedifferentiated parosteal osteosarcoma is characterized histologically by the admixture of low-grade fibroblastic osteosarcoma and a high-grade component typically resembling conventional osteosarcoma or malignant fibrous histiocytoma.
  • This phenotype is rarely described in the dedifferentiated component of a dedifferentiated parosteal osteosarcoma.

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  • (PMID = 18256826.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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2. Latif MJ, Rahman GF, Connery CP: Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus. J Bronchology Interv Pulmonol; 2009 Jul;16(3):188-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus.
  • Sclerosing hemangioma is a rare pulmonary tumor that usually grows as a peripheral intraparenchymal lesion in the lungs.
  • Although some case series have described this rare tumor, endobronchial growth of sclerosing hemangioma is extremely rare, with only 3 reported cases in the literature to date.

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  • (PMID = 23168550.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Ho MM, Howard TJ, Lillemoe KD: Can pancreaticoduodenectomy be used to palliate selective metastatic malignancies? Case report of malignant fibrous histiocytoma. J Gastrointest Surg; 2005 Sep-Oct;9(7):934-7
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  • [Title] Can pancreaticoduodenectomy be used to palliate selective metastatic malignancies? Case report of malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / secondary. Palliative Care. Pancreaticoduodenectomy

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  • (PMID = 16137587.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Kakitsubata Y, Theodorou SJ, Theodorou DJ, Nabeshima K, Kakitsubata S, Friedman PJ: Myofibroblastic inflammatory tumor of the lung: CT findings with pathologic correlation. Comput Med Imaging Graph; 2007 Dec;31(8):607-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Variable degree of fibrous histiocytoma type was observed in all cases.

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  • (PMID = 17719202.001).
  • [ISSN] 0895-6111
  • [Journal-full-title] Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
  • [ISO-abbreviation] Comput Med Imaging Graph
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Lee MH, Kim NR, Ryu JA: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol; 2010 Oct;39(10):981-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Of 23 masses, there were 5 giant cell tumors of the tendon sheath, 4 schwannomas, 3 vascular leiomyomas, 2 benign fibrous histiocytomas, 2 dermatofibrosarcoma protuberans, 2 granular cell tumors, 1 dermatofibroma, 1 fibroma of the tendon sheath, 1 fibromatosis, 1 eccrine spiradenoma, and 1 granulation tissue.
  • Such cases are not common, and fibrous tumors are the most frequent.
  • [MeSH-major] Cysts / diagnostic imaging. Musculoskeletal Diseases / diagnostic imaging. Soft Tissue Neoplasms / diagnostic imaging. Ultrasonography, Doppler, Color / methods

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  • (PMID = 20186412.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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6. Hussein MR: Skin metastasis: a pathologist's perspective. J Cutan Pathol; 2010 Sep;37(9):e1-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin metastasis: a pathologist's perspective.
  • Skin metastasis is defined as the spread of malignant cells from a primary malignancy to the skin.
  • The tumor cells originate either from an internal malignancy or from a primary skin cancer.
  • Generally, skin metastases are encountered in 0.7-9% of all patients with cancer and as such the skin is an uncommon site of metastatic disease when compared to other organs.
  • There is usually a long-time lag between the diagnosis of the primary malignancy and the recognition of the skin metastases.
  • The regional distribution of the skin metastasis, although not always predictable, is related to the location of the primary malignancy and the mechanism of metastatic spread.
  • The relative frequency of skin metastasis correlates with the type of primary cancer, which occurs in each sex.
  • For instance, lung and breast carcinomas are the most common primaries that send skin metastasis in men and women, respectively.
  • Skin metastases usually appear as non-specific groups of discrete firm painless nodules that emerge rapidly without any explanation.
  • Some skin metastasis may mimic specific dermatological conditions such as cutaneous cyst, dermatofibroma, pyogenic granuloma, hemangioma, papular eruptions, herpes zoster eruptions, rapidly infiltrating plaques, alopecic patches, cellulitis and erysipelas.
  • Histologically, the skin metastases usually show features reminiscent of the primary malignancy, but with variable degrees of differentiation.
  • Molecularly, skin metastasis is an organized, non-random and organ-selective process orchestrated by interaction among several heterogeneous molecules, which are largely unknown.
  • Metastasis to the skin is often a pre-terminal event that heralds poor outcome.
  • [MeSH-major] Skin Neoplasms / secondary

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  • (PMID = 19922483.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
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7. Shi WM, Liao WQ, Wu ZW, Pandey P, Mei XY, Qin HH, Xu JH, Shen L: Recurrent cutaneous malignant fibrous histiocytoma. Eur J Dermatol; 2009 Mar-Apr;19(2):187-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent cutaneous malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 19264583.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] France
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8. Micantonio T, Fargnoli MC, Peris K: Giant dermatofibroma appearing during pregnancy. Acta Derm Venereol; 2006;86(1):86-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant dermatofibroma appearing during pregnancy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Skin Neoplasms / diagnosis


9. Asadi Amoli F, Sina AH, Kasai A, Ayan Z: A well-known lesion in an unusual location: infantile myofibroma of the eyelid: a case report and review of literature. Acta Med Iran; 2010 Nov-Dec;48(6):412-6
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  • It has a benign course in the solitary form and fatal in its multiple form.
  • A 4 month male infant referred to Farabi hospital -the referral center for eye diseases- with a 2 month history of a mass in his eyelid with gradual enlargement with no other complaints.
  • When confronting a spindle cell lesion with a nodular or multinodular growth pattern which appears biphasic due to alteration of light and dark staining areas, the surgical pathologist should think to the possibility of myofibroma.
  • Its pattern of growth and architecture rules out the other differential diagnoses like nodular fasciitis, fibrous histiocytoma, infantile fibromatosis, and peripheral primitive neuroectodermal tumor, mesenchymal chondrosarcoma, malignant hemangiopericytoma, juvenile fibrosarcoma and poorly differentiated synovial sarcoma.

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  • (PMID = 21287484.001).
  • [ISSN] 1735-9694
  • [Journal-full-title] Acta medica Iranica
  • [ISO-abbreviation] Acta Med Iran
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Iran
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10. Botrus G, Sciot R, Debiec-Rychter M: Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly. Cancer Genet Cytogenet; 2006 Jan 15;164(2):155-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly.
  • We report a case of a 39-year-old woman with a recurrent aneurysmal fibrous histiocytoma of the right lower leg.
  • Our case highlights the importance of distinguishing this recurrent but benign lesion from similarly appearing malignant skin tumors.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Histiocytoma, Benign Fibrous / genetics. Skin Neoplasms / genetics. Translocation, Genetic

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  • (PMID = 16434321.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ETS translocation variant 6 protein; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-ets; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / proto-oncogene protein bcl-3
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11. Hong Y, Chen S, Zhang JM: [Bilateral diffusive benign fibrous histiocytoma in retrobulbar muscle cone: a case report]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2010 Sep;39(5):548-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bilateral diffusive benign fibrous histiocytoma in retrobulbar muscle cone: a case report].
  • [MeSH-major] Histiocytoma, Benign Fibrous. Orbital Neoplasms

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  • (PMID = 20936733.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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12. Wright NA, Thomas CG, Calame A, Cockerell CJ: Granular cell atypical fibroxanthoma: case report and review of the literature. J Cutan Pathol; 2010 Mar;37(3):380-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The granular cell phenotype has been observed in other cutaneous neoplasms including granular cell tumors, dermatofibromas, dermatofibrosarcoma protuberans, fibrous papules, basal cell carcinomas, leiomyosarcomas, angiosarcomas and primitive polypoid granular cell tumors.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology

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  • (PMID = 19341433.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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13. Kau HC, Yang CF, Liu IT, Kao SC, Hsu WM, Teng MM, Tsai CC: Benign fibrous histiocytoma associated with a frontoethmoidal mucopyocele and orbital abscess. Ophthal Plast Reconstr Surg; 2007 May-Jun;23(3):236-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign fibrous histiocytoma associated with a frontoethmoidal mucopyocele and orbital abscess.
  • Histopathologic examination proved it to be a benign fibrous histiocytoma.
  • Benign fibrous histiocytoma may occur in association with an orbital abscess secondary to mucocele.
  • [MeSH-major] Abscess / complications. Eye Infections, Bacterial / complications. Eyelid Neoplasms / etiology. Histiocytoma, Benign Fibrous / etiology. Mucocele / complications. Orbital Diseases / complications. Paranasal Sinus Diseases / complications. Pseudomonas Infections / complications

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  • (PMID = 17519668.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Takase K, Suzuki H, Matsuoka H: The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report. West Indian Med J; 2010 Jan;59(1):106-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report.
  • Malignant fibrous histiocytoma (MFH) is a type of highly malignant soft tissue sarcoma with a predilection for the extremities of adults.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Muscle, Skeletal / pathology. Muscle, Skeletal / surgery. Reconstructive Surgical Procedures / methods. Shoulder / surgery. Soft Tissue Neoplasms / surgery. Surgical Flaps

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  • (PMID = 20931927.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Jamaica
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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15. Battistella M, Trabelsi S, Terrier-Lacombe MJ, Leboulleux S, Robert C: Hypermetabolic dermatofibroma on Positron Emission Tomography/Computed tomography with 18F-FluoroDeoxyGlucose : a misleading false positive in the follow-up of a metastatic melanoma. Eur J Dermatol; 2008 Jul-Aug;18(4):461-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypermetabolic dermatofibroma on Positron Emission Tomography/Computed tomography with 18F-FluoroDeoxyGlucose : a misleading false positive in the follow-up of a metastatic melanoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Melanoma / diagnosis. Positron-Emission Tomography. Skin Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 18573725.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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16. González-Vela MC, Val-Bernal JF, Martino M, González-López MA, García-Alberdi E, Hermana S: Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma. Histol Histopathol; 2005 07;20(3):801-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma.
  • Dermatofibroma (DF) is a common benign cutaneous tumor with many variants based on alterations in the morphology and composition of its diverse elements.
  • One very infrequent type is sclerotic fibroma-like DF (SF-DF).
  • [MeSH-major] Fibroma / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15944929.001).
  • [ISSN] 0213-3911
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, CD99; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Vimentin
  • [Number-of-references] 21
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17. Baines SJ, Blacklaws BA, McInnes E, McConnell IM: CCH cells are potent stimulators in the allogeneic mixed leucocyte reaction. Vet Immunol Immunopathol; 2007 Oct 15;119(3-4):316-21
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  • Canine cutaneous histiocytoma (CCH) has been identified as a tumour of epidermal Langerhans cells (LCs) on the basis of immunophenotypic studies.
  • Neoplastic Langerhans cells (CCH-LCs) were isolated from lesions of canine cutaneous histiocytoma.
  • [MeSH-major] Dog Diseases / immunology. Histiocytoma, Benign Fibrous / veterinary. Langerhans Cells / immunology. Langerhans Cells / pathology. Lymphocyte Culture Test, Mixed / veterinary

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  • (PMID = 17675250.001).
  • [ISSN] 0165-2427
  • [Journal-full-title] Veterinary immunology and immunopathology
  • [ISO-abbreviation] Vet. Immunol. Immunopathol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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18. Tschoep K, Kohlmann A, Schlemmer M, Haferlach T, Issels RD: Gene expression profiling in sarcomas. Crit Rev Oncol Hematol; 2007 Aug;63(2):111-24
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  • Sarcomas are a heterogeneous group of malignant mesenchymal tumors of difficult classification.
  • These markers give new insight into the pathogenesis of sarcomas, such as malignant fibrous histiocytoma [Lee YF, et al.
  • Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling.


19. Hoshi M, Matsumoto S, Manabe J, Tanizawa T, Shigemitsu T, Izawa N, Takeuchi K, Kawaguchi N: Malignant change secondary to fibrous dysplasia. Int J Clin Oncol; 2006 Jun;11(3):229-35
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  • [Title] Malignant change secondary to fibrous dysplasia.
  • BACKGROUND: Malignant change in fibrous dysplasia (FD) is very rare.
  • This study was carried out to establish some characteristic clinical information about this disorder.
  • METHODS: Four cases with a malignant change in FD out of 128 cases with FD were surgically treated and followed up for a median period of 61.3 months.
  • Histopathologically, two cases were osteosarcoma, one case was malignant fibrous histiocytoma (MFH), and one case was fibrosarcoma.
  • [MeSH-major] Bone Neoplasms / etiology. Bone Neoplasms / pathology. Fibrous Dysplasia of Bone / complications. Sarcoma / etiology. Sarcoma / pathology


20. Dhillon J, Amin MB, Selbs E, Turi GK, Paner GP, Reuter VE: Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change. Am J Surg Pathol; 2009 Jan;33(1):44-9
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  • Mucinous tubular and spindle cell carcinoma is a RCC subtype, which is defined as polymorphous histology wherein the spindled epithelial cell is an inherent carcinomatous component.
  • In addition to the classic mucinous tubular and spindle cell carcinoma morphology, both cases had a sarcomatoid component characterized by predominantly high-grade spindle cells, solid pleomorphic epithelioid cells, and malignant fibrous histiocytoma-like storiform patterns.

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  • (PMID = 18941398.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Capovilla M, Birembaut P, Cucherousset J, Ploton D, de Saint-Maur PP, Fléjou JF, Lesec G: Pleomorphic hyalinizing angiectatic tumor of soft parts: ultrastructural analysis of a case with original features. Ultrastruct Pathol; 2006 Jan-Feb;30(1):59-64
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  • [Title] Pleomorphic hyalinizing angiectatic tumor of soft parts: ultrastructural analysis of a case with original features.
  • Pleomorphic hyalinizing angiectatic tumor, a rare neoplasm of uncertain lineage resembling malignant fibrous histiocytoma and schwannoma, was first described in 1996 by M. E. F.
  • To date, less than 100 cases have been reported in the international literature.
  • All lesions are composed of sheets and fascicles of spindled and pleomorphic cells associated with clusters of thick-walled ectatic vessels surrounded by a perivascular hyaline material and inflammatory cells such as mast cells.
  • The authors report histological and ultrastructural characteristics of a new case of PHAT excised from the right buttock of a 66-year-old man with the presence of ganglion-like cells, a feature that has not been previously reported, and unusual central ischemic necrosis.
  • The features of this case are suggestive of a fibroblastic origin.
  • [MeSH-minor] Aged. Angiofibroma / diagnosis. Biomarkers, Tumor / metabolism. Blood Vessels / pathology. Diagnosis, Differential. Fibroma / diagnosis. Giant Cells / pathology. Histiocytoma, Malignant Fibrous / diagnosis. Humans. Hyalin / metabolism. Immunoenzyme Techniques. Male. Neurilemmoma / diagnosis

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  • (PMID = 16517471.001).
  • [ISSN] 1521-0758
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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22. Sakao Y, Tomimitsu S, Takeda Y, Natsuaki M, Itoh T: Malignant fibrous histiocytoma of the trachea. Jpn J Thorac Cardiovasc Surg; 2005 May;53(5):276-9
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  • [Title] Malignant fibrous histiocytoma of the trachea.
  • We experienced a rare case of malignant fibrous histiocytoma (MFH) arising in the trachea.
  • [MeSH-major] Histiocytoma, Benign Fibrous / surgery. Tracheal Neoplasms / surgery

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  • Histologic diagnoses were as follows: malignant fibrous histiocytoma in 6, liposarcoma in 3, malignant peripheral nerve sheath tumor in 3, Ewing/primitive neuroectodermal tumor (PNET) in 2, and miscellaneous in 10 patients.

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  • (PMID = 19467578.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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24. Goto T, Okuma T, Nakada I, Hozumi T, Kondo T: [Preoperative adjuvant therapy for primary malignant bone tumors]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1750-4
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  • Nowadays, in highgrade bone sarcomas, especially in osteosarcoma, Ewing.s sarcoma and malignant fibrous histiocytoma of bone, adjuvant chemotherapy including neoadjuvant or preoperative chemotherapy is usually performed.

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  • (PMID = 18030009.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; UM20QQM95Y / Ifosfamide; VAC protocol; VACA protocol; VAIA protocol
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25. Rhomberg W: The radiation response of sarcomas by histologic subtypes: a review with special emphasis given to results achieved with razoxane. Sarcoma; 2006;2006(1):87367
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  • The response rate is less than 50% in malignant fibrous histiocytomas, synovial, neurogenic, and other rare soft tissue sarcomas.

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  • (PMID = 17040092.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC1510952
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26. Pongpudpunth M, Keady M, Mahalingam M: Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis? J Cutan Pathol; 2009 Oct;36(10):1083-8
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  • [Title] Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis?
  • BACKGROUND: The etiopathogenesis of dermatofibroma (DF), a common benign fibrohistiocytic tumor, is debatable.
  • [MeSH-major] Elastic Tissue / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19615002.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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27. Maier PC, Auw-Hädrich C, Reinhard T: [Recurrent fibrous histiocytoma at the corneoscleral limbus]. Klin Monbl Augenheilkd; 2008 Jan;225(1):99-100
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  • [Title] [Recurrent fibrous histiocytoma at the corneoscleral limbus].
  • [Transliterated title] Rezidivierendes fibröses Histiozytom am korneoskleralen Limbus.
  • This case report describes a rare fibrous histiocytoma at the corneoscleral limbus in a 10-year-old boy.
  • In our patient the tumour was histologically classified as benign, however, it presented with an invasive growth pattern and recurrency, so that a penetrating sclerokeratoplasty became necessary.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Keratoplasty, Penetrating. Limbus Corneae / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 18236380.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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28. Nooij MA, Whelan J, Bramwell VH, Taminiau AT, Cannon S, Hogendoorn PC, Pringle J, Uscinska BM, Weeden S, Kirkpatrick A, Glabbeke Mv, Craft AW, European Osteosarcoma Intergroup: Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study. Eur J Cancer; 2005 Jan;41(2):225-30
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  • [Title] Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study.
  • There are limited data that define the role of chemotherapy in the treatment of high-grade spindle cell sarcomas of bone, other than osteosarcoma or malignant fibrous histiocytoma (MFH-B).
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / drug therapy. Rare Diseases / drug therapy. Sarcoma / drug therapy


29. Katsuura Y, Ishida H, Komatsuda T, Furukawa K, Yagisawa H, Yamada M, Ohno H, Kotanagi H, Miyauchi T, Saitoh K: Malignant fibrous histiocytoma of the spleen: report of a case and literature review. Abdom Imaging; 2006 Jul-Aug;31(4):453-6
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  • [Title] Malignant fibrous histiocytoma of the spleen: report of a case and literature review.
  • There is a marked paucity of reports on malignant fibrous histiocytoma (MFH) of the spleen in the literature, and there are no previous reports of its color Doppler sonographic (US) and contrast-enhanced US findings.
  • We report on an 82-year-old male with splenic MFH (inflammatory subtype), with an emphasis on color Doppler and contrast-enhanced US findings.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / ultrasonography. Splenic Neoplasms / ultrasonography

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  • (PMID = 16447082.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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30. Lehnhardt M, Daigeler A, Homann HH, Hauser J, Langer S, Steinsträsser L, Soimaru C, Puls A, Steinau HU: [Importance of specialized centers in diagnosis and treatment of extremity-soft tissue sarcomas. Review of 603 cases]. Chirurg; 2009 Apr;80(4):341-7
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  • Due to the disorder's rarity, multitude of subgroups, sometimes varying histopathologic appearance, and occasionally inadequate biopsy specimens, diagnosis and grading are challenging.
  • Liposarcoma and malignant fibrous histiocytoma were the most often diagnosed subgroups at 24% and 22.6%, respectively.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Diagnostic Errors. Female. Germany. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / diagnosis. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / diagnosis. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Staging. Nerve Sheath Neoplasms / diagnosis. Nerve Sheath Neoplasms / pathology. Nerve Sheath Neoplasms / surgery. Radiotherapy, Adjuvant. Referral and Consultation. Retrospective Studies. Young Adult

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  • (PMID = 18523742.001).
  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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31. Leow AM, Halim AS, Wan Z: Reconstructive treatment following resection of high-grade soft-tissue sarcomas of the lower limb. J Orthop Surg (Hong Kong); 2005 Apr;13(1):58-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Of 8 patients (6 women and 2 men) aged between 19 and 65 years, 4 had malignant fibrous histiocytoma, one had malignant peripheral nerve sheath tumour, one had synovial sarcoma, one had recurrent liposarcoma, and one had epitheloid sarcoma.

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  • (PMID = 15872402.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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32. Rzyman W, Jaskiewicz K, Murawski M, Sternau A, Marjanski T, Karmolinski A, Dziadziuszko R: Primary malignant fibrous histiocytoma of the lung. Thorac Cardiovasc Surg; 2007 Apr;55(3):186-9
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  • [Title] Primary malignant fibrous histiocytoma of the lung.
  • BACKGROUND: Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Pneumonectomy

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  • (PMID = 17410507.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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33. Min WK, Kim SY, Oh CW, Kim SJ, Park TI, Koo KH: Malignant fibrous histiocytoma arising in the area of total hip replacement. Joint Bone Spine; 2008 May;75(3):319-21
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  • [Title] Malignant fibrous histiocytoma arising in the area of total hip replacement.
  • The biopsy confirmed the malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Arthroplasty, Replacement, Hip / adverse effects. Femur Head Necrosis / surgery. Histiocytoma, Malignant Fibrous / etiology

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  • (PMID = 17977772.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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34. Choi KH, Baek HA, Park HS, Jang KY, Jin GY, Kim MH, Lee YC, Moon WS, Chung MJ: Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung. Pathol Int; 2008 Nov;58(11):735-40
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  • [Title] Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung.
  • Pulmonary sclerosing hemangioma is generally considered a rare neoplasm presenting as a solitary benign nodule.
  • During routine medical examination multiple abnormal nodular shadows were detected in the right lower lung field on chest X-ray in a 48-year-old asymptomatic woman.
  • All of these lesions had typical features of sclerosing hemangioma.
  • The authors call this unusual growth pattern of sclerosing hemangioma a 'pneumonic pattern'.
  • [MeSH-major] Adenoma / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 18844941.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1
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35. Utsunomiya D, Ikeda O, Ideta I, Hirayama T, Yamashita Y, Kamio T: Malignant fibrous histiocytoma arising from the aortic wall mimicking a pseudoaneurysm with ulceration. Circ J; 2007 Oct;71(10):1659-61
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  • [Title] Malignant fibrous histiocytoma arising from the aortic wall mimicking a pseudoaneurysm with ulceration.
  • Malignant fibrous histiocytoma of the thoracic aorta associated with ulcer-like projection has not been reported previously.
  • [MeSH-major] Aorta, Thoracic. Aortic Aneurysm, Thoracic / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Ulcer / diagnosis. Vascular Neoplasms / diagnosis

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  • (PMID = 17895569.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Cardoso R, Massone C, Soyer HP, Hofmann-Wellenhof R: Additional dermoscopic presentation of haemosiderotic dermatofibroma. Br J Dermatol; 2007 Jan;156(1):199-200
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  • [Title] Additional dermoscopic presentation of haemosiderotic dermatofibroma.
  • [MeSH-major] Dysplastic Nevus Syndrome / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • [CommentOn] Br J Dermatol. 2006 Feb;154(2):244-50 [16433792.001]
  • (PMID = 17199605.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] England
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37. Sato A, Ishida H, Komatsuda T, Yagisawa H: Spontaneous ruptured hepatic malignant fibrous histiocytoma. J Med Ultrason (2001); 2006 Dec;33(4):255-6
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  • [Title] Spontaneous ruptured hepatic malignant fibrous histiocytoma.

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  • [Cites] Cancer. 1980 Jan 1;45(1):167-78 [6243239.001]
  • (PMID = 27277985.001).
  • [ISSN] 1346-4523
  • [Journal-full-title] Journal of medical ultrasonics (2001)
  • [ISO-abbreviation] J Med Ultrason (2001)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; liver tumor / malignant fibrous histiocytoma / rupture / ultrasound
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38. Lakhani P, Rubesin SE, Zhang PJ: Malignant fibrous histiocytoma of the pharynx. AJR Am J Roentgenol; 2005 Mar;184(3 Suppl):S12-3
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  • [Title] Malignant fibrous histiocytoma of the pharynx.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Pharyngeal Neoplasms / pathology

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  • (PMID = 15728001.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Maccauro G, Liuzza F, Muratori F, Gosheger G, Salgarello M, Logroscino CA: A particular solution in the treatment of primitive neoplasms of the distal third of the tibia. Presentation of a clinical case and review of the literature. Arch Orthop Trauma Surg; 2006 Dec;126(10):713-8
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  • [Title] A particular solution in the treatment of primitive neoplasms of the distal third of the tibia. Presentation of a clinical case and review of the literature.
  • The authors describe the diagnostic procedure and a particular surgical strategy of limb salvage in a case of malignant fibrous histiocytoma located at the distal third of the tibia, in particular pointing out the difficulties in restoring the continuity of the skeletal tissues and of the muscle, and with a review of the relevant literature.
  • [MeSH-major] Bone Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery. Salvage Therapy. Tibia

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  • (PMID = 16896746.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 37
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40. Conley AP, Trent J, Zhang W: Recent progress in the genomics of soft tissue sarcomas. Curr Opin Oncol; 2008 Jul;20(4):395-9
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  • Genomic analysis provides a means to elucidate new gene signatures or pathways for possible therapeutic manipulation, predictors of prognosis, and improved diagnostic classification.
  • RECENT FINDINGS: Genomic profiling of soft tissue sarcomas subtypes reveals a propensity for tumors of less karyotypic diversity to segregate from the more pleomorphic subtypes.
  • Certain statistical methods such as support vector machine analysis can distinguish pleomorphic subgroups such as malignant fibrous histiocytomas from other sarcomas.

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  • (PMID = 18525334.001).
  • [ISSN] 1531-703X
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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41. Kluger N, Cotten H, Magana C, Pinquier L: Dermatofibroma occurring within a tattoo: report of two cases. J Cutan Pathol; 2008 Jul;35(7):696-8
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  • [Title] Dermatofibroma occurring within a tattoo: report of two cases.
  • [MeSH-major] Coloring Agents / adverse effects. Histiocytoma, Benign Fibrous / etiology. Skin Neoplasms / etiology. Tattooing / adverse effects
  • [MeSH-minor] Adult. Humans. Male. Skin / injuries. Skin / pathology

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  • (PMID = 18582244.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Coloring Agents
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42. Cox NH: Halo asteatotic eczema localized around a dermatofibroma in acute-onset leg oedema. Br J Dermatol; 2008 Aug;159(2):496
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  • [Title] Halo asteatotic eczema localized around a dermatofibroma in acute-onset leg oedema.
  • [MeSH-major] Eczema / pathology. Edema / pathology. Histiocytoma, Benign Fibrous / pathology. Leg Dermatoses / pathology. Skin Neoplasms / pathology


43. Collin F, Gelly-Marty M, Bui Nguyen Binh M, Coindre JM: [Soft tissue sarcomas: current data in the field of pathology]. Cancer Radiother; 2006 Feb-Mar;10(1-2):7-14
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  • New data led to the revision of the WHO classification.
  • Malignant fibrous histiocytoma is no longer considered as an entity.
  • Haemangiopericytoma underwent reappraisal and was put in the same category as solitary fibrous tumour.

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  • (PMID = 16310396.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 28
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44. Kuo FY, Eng HL, Chen SH, Huang HY: Intramuscular juvenile xanthogranuloma in an adult: a case report with immunohistochemical study. Arch Pathol Lab Med; 2005 Feb;129(2):e31-4
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  • Juvenile xanthogranuloma (JXG) is a self-limited cutaneous lesion that most often occurs in infancy.
  • Approximately 10% to 30% of JXGs occur in adult patients, where most cases present as cutaneous papulonodular lesions, with only rare cases involving extracutaneous sites.
  • The authors hereby describe a case of adult intramuscular JXG that occurred in a woman who initially had a dermal JXG in the nasal skin at the age of 48 years and then developed a slow-growing painless intramuscular JXG in the right forearm 4 years later.
  • However, central fibrosis and a focal storiform arrangement of spindled fibroblast-like cells in the intramuscular lesion resulted in a histologic pattern reminiscent of a fibrous histiocytoma.
  • This case underscores the fact that intramuscular JXG can also involve adult patients and its morphologic variation is more likely to be time dependent rather than site specific or age related.
  • [MeSH-major] Muscular Diseases / diagnosis. Xanthogranuloma, Juvenile / diagnosis
  • [MeSH-minor] Female. Humans. Middle Aged. Skin Diseases / pathology


45. Jarry J, Belleannee G, Laurent C, Coindre JM, Evrard S: Primary malignant fibrous histiocytoma of the pancreas: benefit of the multidisciplinary approach. Eur J Gastroenterol Hepatol; 2010 Jun;22(6):765-8
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  • [Title] Primary malignant fibrous histiocytoma of the pancreas: benefit of the multidisciplinary approach.
  • Primary malignant fibrous histiocytoma (MFH) is an exceedingly rare tumour of the pancreas with a high recurrence rate and a poor prognosis.
  • In this report, the authors present the case of a 45-year-old man who was first operated on for a primary MFH of the pancreas.
  • We report a case of a primary MFH of the pancreas treated by using a multidisciplinary approach resulting in an above average survival rate.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / therapy. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / therapy

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  • (PMID = 20446353.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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46. Wibmer C, Leithner A, Zielonke N, Sperl M, Windhager R: Increasing incidence rates of soft tissue sarcomas? A population-based epidemiologic study and literature review. Ann Oncol; 2010 May;21(5):1106-11
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  • The most common histotypes were sarcoma not otherwise specified (36%), leiomyosarcoma (24%), liposarcoma (12%), malignant fibrous histiocytoma (9%) and fibrosarcoma (5%).
  • CONCLUSIONS: This study has analyzed the most recent data from a European population in comparison with seven international studies.
  • The incidence rate of STS in Austria ranges in the lower half of the international incidence rates (1.8-5.0 per 100,000 per year).

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  • (PMID = 19858086.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 17
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47. Dei Tos AP: Classification of pleomorphic sarcomas: where are we now? Histopathology; 2006 Jan;48(1):51-62
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  • [Title] Classification of pleomorphic sarcomas: where are we now?
  • Until a decade ago, so-called pleomorphic and storiform malignant fibrous histiocytoma (MFH) represented the most frequently diagnosed sarcoma, accounting for approximately 40% of adult mesenchymal malignancies.
  • However, the latest World Health Organization classification of soft tissue tumours considers MFH a synonym for undifferentiated pleomorphic sarcoma.
  • With the advent of electron microscopy, immunohistochemistry and molecular genetics, it became clear that the so-called "facultative fibroblast" theory had no scientific grounds and, in 1992, a milestone paper eventually brought attention to the concept that MFH merely represented a morphological pattern shared by a wide variety of poorly differentiated malignant neoplasms, which include specific subtypes of pleomorphic sarcomas.
  • Currently, accurate subclassification of pleomorphic sarcomas is mandatory as it enables recognition of non-sarcomatous lesions as well as pleomorphic neoplasms not associated with aggressive behaviour.
  • Furthermore, as myogenic differentiation predicts aggressive clinical behaviour among pleomorphic sarcomas, precise histotyping allows prognostic stratification of patients.
  • [MeSH-major] Sarcoma / classification. Soft Tissue Neoplasms / classification

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  • (PMID = 16359537.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 63
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48. Sharma H, Jane MJ, Reid R: Scapulo-humeral Paget's sarcoma: Scottish Bone Tumour Registry experience. Eur J Cancer Care (Engl); 2005 Sep;14(4):367-72
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  • Histology showed predominantly osteosarcoma (n = 12), followed by pleomorphic sarcoma (n = 2), malignant fibrous histiocytoma (n = 1) and fibrosarcoma (n = 1).


49. Papagelopoulos PJ, Mavrogenis AF, Galanis EC, Chloros GD, Papaparaskeva KT: Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report. J Bone Joint Surg Am; 2005 Feb;87(2):399-403
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report.
  • [MeSH-major] Bone Neoplasms / pathology. Femur / pathology. Histiocytoma, Benign Fibrous / pathology. Neurofibromatosis 1 / pathology


50. Ismail Y, Watson S: Benign fibrous histiocytoma (dermatofibroma) of the face: a rare entity requiring aggressive surgical management. J Plast Reconstr Aesthet Surg; 2010 Aug;63(8):e647
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  • [Title] Benign fibrous histiocytoma (dermatofibroma) of the face: a rare entity requiring aggressive surgical management.
  • [MeSH-major] Facial Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery

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  • (PMID = 20378438.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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51. Nonaka D: A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). Histopathology; 2008 Jun;52(7):896-7
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  • [Title] A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Dendritic Cells / metabolism. Histiocytoma, Benign Fibrous / pathology. Monocytes / metabolism. Skin Neoplasms / pathology

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  • (PMID = 18462367.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.3.2.13 / Factor XIIIa
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52. Curcó N, Pagerols X, García M, Tarroch X, Vives P: Atrophic dermatofibroma accompanied by aneurysmatic characteristics. J Eur Acad Dermatol Venereol; 2006 Mar;20(3):331-3
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  • [Title] Atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • A 40-year-old man presented a painful haemorrhagic plaque on his chest in the same location where a nodular lesion had been presented for many years.
  • The lesion diagnosed as an anetoderma was excised and the biopsy showed an atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • [MeSH-major] Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16503899.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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53. Gaumann A, Bode-Lesniewska B, Zimmermann DR, Fanburg-Smith JC, Kirkpatrick CJ, Hofstädter F, Woenckhaus M, Stoehr R, Obermann EC, Dietmaier W, Hartmann A: Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases. Virchows Arch; 2008 Nov;453(5):473-84
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  • [Title] Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases.
  • Pulmonary artery sarcoma (PAS) were studied by morphologic, immunohistochemical, and molecular genetic methods of the Wnt pathway.
  • PAS were classified as epithelioid (n = 4) or malignant fibrous histiocytoma (MFH; spindled/pleomorphic, n = 4), myxofibrosarcoma (n = 8), and one each hemangiopericytoma-like or malignant inflammatory myofibroblastic tumor-like.
  • [MeSH-major] Adenomatous Polyposis Coli Protein / metabolism. Pulmonary Artery / pathology. Sarcoma / classification. Signal Transduction / physiology. Tunica Intima / pathology. Vascular Neoplasms / classification. beta Catenin / metabolism

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  • (PMID = 18807072.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / Cyclin A; 0 / beta Catenin; 136601-57-5 / Cyclin D1
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54. Miura N, Shoji F, Kawano D, Morodomi Y, Ito K, Yano T, Maehara Y: A pulmonary sclerosing hemagioma with an increasing uptake on PET. Thorac Cardiovasc Surg; 2009 Dec;57(8):498-9
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  • [Title] A pulmonary sclerosing hemagioma with an increasing uptake on PET.
  • Pulmonary sclerosing hemangioma is a relatively rare neoplasm of the lung.
  • Although there have been five previous case reports that address the 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) findings in a sclerosing hemangioma of the lung, no report has demonstrated an interval change in the FDG-PET findings.
  • This report describes a case of pulmonary sclerosing hemangioma which presented with an increase of uptake of FDG-PET after about one years' follow-up.
  • [MeSH-major] Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography. Pulmonary Sclerosing Hemangioma / radionuclide imaging

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  • [Copyright] Copyright Georg Thieme Verlag KG Stuttgart . New York.
  • (PMID = 20013629.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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55. Benassi MS, Ponticelli F, Azzoni E, Gamberi G, Pazzaglia L, Chiechi A, Conti A, Spessotto P, Scapolan M, Pignotti E, Bacchini P, Picci P: Altered expression of urokinase-type plasminogen activator and plasminogen activator inhibitor in high-risk soft tissue sarcomas. Histol Histopathol; 2007 09;22(9):1017-24
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  • In recent years, classification of soft-tissue sarcomas (STS) has improved with cytogenetic analyses, but their clinical behavior is still not easily predictable.
  • Real-time PCR was performed on human STS cell lines and tissues from highly malignant STS, including leiomyosarcomas and malignant fibrous histiocytomas, to evaluate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1).

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  • (PMID = 17523079.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / PLAUR protein, human; 0 / Plasminogen Activator Inhibitor 1; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 0 / Receptors, Urokinase Plasminogen Activator; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator
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56. Monteagudo B, Alvarez-Fernández JC, Iglesias B, de las Heras C, Cacharrón JM: [Multiple eruptive dermatofribromas in a patient with Down's syndrome]. Actas Dermosifiliogr; 2005 Apr;96(3):199
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  • [Transliterated title] Dermatofibromas eruptivos múltiples en un paciente con síndrome de Down.
  • [MeSH-major] Down Syndrome / complications. Histiocytoma, Benign Fibrous / complications. Skin Neoplasms / complications

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  • (PMID = 16476369.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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57. Domson GF, Shahlaee A, Reith JD, Bush CH, Gibbs CP: Infarct-associated bone sarcomas. Clin Orthop Relat Res; 2009 Jul;467(7):1820-5
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  • Sixty percent of cases arise about the knee and most are malignant fibrous histiocytomas.
  • [MeSH-major] Bone Neoplasms / complications. Histiocytoma, Malignant Fibrous / complications. Infarction / complications. Sarcoma / complications

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  • (PMID = 19229663.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2690751
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58. Tse GM, Tan PH, Lui PC, Putti TC: Spindle cell lesions of the breast--the pathologic differential diagnosis. Breast Cancer Res Treat; 2008 May;109(2):199-207
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  • In the biphasic lesions with predominance of spindle cells with benign epithelial component, fibroepithelial lesions including fibroadenomas and phyllodes tumors are the most common, followed by pseudoangiomatous stromal hyperplasia, hamartoma and adenomyoepithelioma.
  • For monophasic lesions with pure pleomorphic spindle cell only, the monophasic metaplastic carcinoma is more common than the rare primary sarcomas like malignant fibrous histiocytoma, angiosarcoma, and other high grade sarcomas.

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  • (PMID = 17636400.001).
  • [ISSN] 0167-6806
  • [Journal-full-title] Breast cancer research and treatment
  • [ISO-abbreviation] Breast Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 57
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59. Wen QL, Meng MB, Zou BW, Lu Y: Malignant fibrous histiocytoma like pleomorphic leiomyosarcoma with laryngeal cancer as a second primary neoplasm: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):1013-7
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  • [Title] Malignant fibrous histiocytoma like pleomorphic leiomyosarcoma with laryngeal cancer as a second primary neoplasm: a case report.
  • Pleomorphic leiomyosarcoma (P-LMS) may be easily confused with a malignant fibrous histiocytoma (MFH) as both may share nonspecific morphologic features.
  • It is reported that the larynx is the most common site for a second primary neoplasm (SPN) in a patient with a head and neck malignancy, although an SPN of the larynx following a P-LMS is extremely rare.
  • CASE: A 57-year-old male initially underwent fine needle aspiration (FNA) of a soft tissue tumor (STS) located in the left upper arm.
  • FNA showed the presence of clustered, large tumor cells with clear, eosinophilic and ill-defined cytoplasm and pleomorphic nuclei.
  • CONCLUSION: This is the first case report of a patient with a P-LMS who then developed laryngeal squamous carcinoma as an SPN.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Laryngeal Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Second Primary / pathology


60. Kaya G, Augsburger E, Chavaz P, Saurat JH: CD44 and hyaluronate expression in follicular mucinosis. J Cutan Pathol; 2006 Mar;33(3):227-30
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  • Stromal HA accumulation is associated with decreased or lost expression of CD44 in perifollicular solitary cutaneous myxoma, myxoid dermatofibroma, and dermatofibrosarcoma protuberans.
  • METHODS: We examined the expression of CD44 and HA in the skin biopsy specimens of 10 patients with follicular mucinosis by using CD44-specific antibodies and biotinylated HA-binding protein (HABP), respectively.

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  • (PMID = 16466510.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers; 0 / Mucins; 9004-61-9 / Hyaluronic Acid
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61. Thomas DM, O'Sullivan B, Gronchi A: Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management. Expert Rev Anticancer Ther; 2009 Aug;9(8):1145-57
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  • The most common adult subtypes are liposarcomas and leiomyosarcomas, followed by pleomorphic sarcoma/malignant fibros histiocytoma (an entity not always easily distinguishable from dedifferentiated liposarcoma).
  • Novel targeted therapeutic agents that target specific amplification or translocation products offer promise for subsets of these diseases.

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  • (PMID = 19671034.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 93
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62. Quatresooz P, Paquet P, Hermanns-Lê T, Piérard GE: Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review). Int J Mol Med; 2008 Oct;22(4):403-9
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  • [Title] Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review).
  • In normal skin, Factor XIIIa is expressed in specific dermal dendrocytes (DD) derived from the monocyte/macrophage lineage or from a mesenchymal origin.
  • DD are located predominantly around the microvasculature in the adventitial dermis, at the dermo-epidermal junction, and around skin appendages, but normally not within the epidermis.
  • Increased numbers of Factor XIIIa+ DD are present in a host of specific cutaneous inflammatory and fibrotic conditions.
  • In tumor pathology, immunophenotypic differences are found between dermatofibromas and other fibrohistiocytic entities, most notably dermatofibrosarcoma protuberans.
  • In addition, Factor XIIIa+ DD are likely to be involved in the progression and regression of some malignancies including cutaneous melanoma and basal cell carcinoma.
  • [MeSH-major] Dendritic Cells / metabolism. Factor XIIIa / metabolism. Skin / cytology

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  • (PMID = 18813845.001).
  • [ISSN] 1107-3756
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.3.2.13 / Factor XIIIa
  • [Number-of-references] 124
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63. Ozdemir F, Kilinc I, Akalin T: Homogeneous blue pigmentation in dermatofibroma simulating a blue naevus. J Eur Acad Dermatol Venereol; 2006 Jul;20(6):733-4
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  • [Title] Homogeneous blue pigmentation in dermatofibroma simulating a blue naevus.
  • A case with a pigmented skin lesion that was diagnosed as a blue naevus on clinical and dermoscopic grounds and histopathologically confirmed as a dermatofibroma is presented.
  • By means of this case, we define dermatofibroma as a new exception for 'homogeneous blue pigmentation' on dermoscopy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Nevus, Blue / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Skin Pigmentation

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  • (PMID = 16836506.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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64. Pu Q, Liu LX, Che GW, Wang Y, Kou YL, Ma L, Zhu YK, Mei JD: [The feasibility study in the treatment of benign pulmonary diseases by single-direction complete video-assisted thoracoscopic lobectomy]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2010 May;41(3):548-50
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  • [Title] [The feasibility study in the treatment of benign pulmonary diseases by single-direction complete video-assisted thoracoscopic lobectomy].
  • OBJECTIVE: To explore the feasibility and safety of single-direction video-assisted thoracoscopic lobectomy in the treatment of benign pulmonary diseases.
  • METHODS: From May 2006 to Dec 2009, 60 patients with benign pulmonary diseases were treated by single-direction complete video-assisted thoracoscopic lobectomy.
  • Nine cases were bronchiectasis, 7 bronchial cyst, 7 tuberculoma, 11 inflammatory pseudotumor, 6 sclerosing hemangioma, 4 hamartoma, 2 atelectasis with bronchial stenosis, 2 pulmonary aspergillosis, 2 pulmonary sequestration, 8 multiple bullae and 2 cases of mid-lobe syndrome.
  • CONCLUSION: Single-direction complete video-assisted thoracoscopic lobectomy is feasible and safe in the treatment of benign pulmonary diseases.
  • [MeSH-major] Lung Diseases / surgery. Pneumonectomy / methods. Thoracic Surgery, Video-Assisted / methods

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  • (PMID = 20629338.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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65. Vetter M, Germann G, Bickert B, Sauerbier M: Current strategies for sarcoma reconstruction at the forearm and hand. J Reconstr Microsurg; 2010 Sep;26(7):455-60
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  • The most common tumor type was the myxoid fibrous histiocytoma in 10 cases.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Child. Child, Preschool. Combined Modality Therapy. Disability Evaluation. Female. Fibula / transplantation. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Humans. Infant. Limb Salvage. Male. Microsurgery / methods. Middle Aged. Neoadjuvant Therapy. Neoplasm Recurrence, Local. Neoplasm Staging. Retrospective Studies. Surveys and Questionnaires

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  • [Copyright] (c) Thieme Medical Publishers.
  • (PMID = 20458673.001).
  • [ISSN] 1098-8947
  • [Journal-full-title] Journal of reconstructive microsurgery
  • [ISO-abbreviation] J Reconstr Microsurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Meis-Kindblom JM: Clear cell sarcoma of tendons and aponeuroses: a historical perspective and tribute to the man behind the entity. Adv Anat Pathol; 2006 Nov;13(6):286-92
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  • Ultrastructural and immunohistochemical studies have shown melanocytic differentiation, whereas molecular genetic studies have shown cytogenetic rearrangements resulting in a EWSR1-ATF1 fusion gene that is characteristic but not entirely unique for clear cell sarcoma (similar fusion genes are also seen in angiomatoid fibrous histiocytoma).
  • Detection of this fusion gene and the absence of BRAF gene mutations clearly distinguish clear cell sarcoma from cutaneous melanoma.
  • Thus, clear cell sarcoma maintains the status of a unique yet enigmatic clinicopathologic entity of ever increasing complexity 40 years after its original description by an extraordinarily gifted man.
  • [MeSH-major] Medical Oncology / history. Pathology / history. Sarcoma, Clear Cell / pathology. Soft Tissue Neoplasms / pathology. Tendons

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  • (PMID = 17075294.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits; Review
  • [Publication-country] United States
  • [Number-of-references] 33
  • [Personal-name-as-subject] Enzinger F
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67. Kim BG, Chang IT, Park JS, Choi YS, Kim GH, Park ES, Choi CH: Transanal excision of a malignant fibrous histiocytoma of anal canal: a case report and literature review. World J Gastroenterol; 2008 Mar 7;14(9):1459-62
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  • [Title] Transanal excision of a malignant fibrous histiocytoma of anal canal: a case report and literature review.
  • Malignant fibrous histiocytoma, which is composed of spindle-shaped cells arranged in a pleomorphic and storiform pattern, is rarely found in the colorectum.
  • We report a case of a 63-year-old woman with an ulcerative lesion in the anorectal junction and a final diagnosis of malignant fibrous histiocytoma.
  • To our knowledge, this is the first case reported in the English literature of a malignant fibrous histiocytoma treated with the transanal local excision and adjuvant radiotherapy.
  • This report showed that this approach is selectively reserved for early-stage malignant fibrous histiocytoma and for those patients who refuse radical surgery because of the risk in a permanent colostomy.
  • [MeSH-major] Anus Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery. Proctoscopy / methods

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  • (PMID = 18322967.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 29
  • [Other-IDs] NLM/ PMC2693701
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68. Sak SD, Koseoglu RD, Demirag F, Akbulut H, Gungor A: Alveolar adenoma of the lung. Immunohistochemical and flow cytometric characteristics of two new cases and a review of the literature. APMIS; 2007 Dec;115(12):1443-9
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  • Alveolar adenoma is a rare and benign tumour of the lung that usually presents in asymptomatic patients as a coin lesion on chest radiography.
  • Immunohistochemical analysis may aid in the characterization of alveolar adenoma and discriminate this condition from other types of benign lesions of the lung.
  • An indolent clinical progression and absence of recurrence and metastasis after complete resection are the most important characteristics indicative of the benign nature of alveolar adenoma.
  • Differential diagnoses include sclerosing hemangioma, papillary adenoma, lymphangioma, atypical adenomatous hyperplasia and bronchioloalveolar carcinoma.

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  • (PMID = 18184418.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
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69. Steff M, Maillard H, Wastiaux H, Prophette B, Celerier P: [Congenital histiocytoma: a benign disease]. Ann Dermatol Venereol; 2009 Mar;136(3):269-72
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  • [Title] [Congenital histiocytoma: a benign disease].
  • BACKGROUND: We report on a newborn presenting a solitary congenital skin nodule due to Langerhans cell histiocytosis.
  • This benign lesion is rare and has been described in the literature under a variety of names; there is no consensus regarding treatment.
  • Histological examination of a skin biopsy showed a proliferation of histiocytes throughout the dermis with an immunohistochemical profile of Langerhans cells.
  • The lesions noted consisted of a solitary brownish nodule measuring 1cm which was congenital in almost all cases, often ulcerated and exhibited no predilection for any particular body site.
  • It appears necessary to differentiate between congenital and other forms of histiocytoma since therapeutic strategies differ.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Diseases / pathology

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  • (PMID = 19328311.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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70. Gomez-Moyano E, Vera-Casaño A, Martinez-Garcia S, Sanz-Trelles A, Crespo-Erchiga V: Two cases of dermatomyofibroma (plaque-like dermal fibromatosis). Int J Dermatol; 2010 Aug;49(8):914-7
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  • BACKGROUND: Dermatomyofibroma is a rare but distinct benign cutaneous mesenchymal neoplasm of fibroblastic/myofibroblastic differentiation.
  • CASE REPORT: We present a) a new case of dermatomyofibroma in an 11-month-old male infant, the youngest case reported to date, and b) the second reported case of a giant annular dermatomyofibroma, measuring 10 cm × 6 cm, in a 52-year-old woman.
  • In both cases, histological examination showed a spindle-cell proliferation embedded among the collagen fibers of the dermis, arranged predominantly parallel to the skin surface.
  • CONCLUSION: Dermatologists and pediatricians should be aware of this benign entity in order to avoid unnecessary treatment.
  • [MeSH-major] Dermis / pathology. Fibroblasts / pathology. Histiocytoma, Benign Fibrous / diagnosis. Muscle, Smooth / pathology. Skin Neoplasms / diagnosis

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  • [Copyright] © 2010 The International Society of Dermatology.
  • (PMID = 21174375.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Choudhury M, Nangia A, Singh SK, Pujani M, Thomas S: Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):985-8
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  • [Title] Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report.
  • CASE: A case of recurrent primary malignant fibrous histiocytoma (MFH) occurred in the breast in a 32-year-old woman.
  • CONCLUSION: Malignant fibrous histiocytoma of the breast is a rare entity, and a complete clinicopathologic correlation with immunohistochemical profile is essential to arrive at a correct diagnosis and guide appropriate management of the patient.
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology

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  • (PMID = 21053583.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Fine SW, Lisanti MP, Argani P, Li M: Caveolin-3 is a sensitive and specific marker for rhabdomyosarcoma. Appl Immunohistochem Mol Morphol; 2005 Sep;13(3):231-6
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  • Fifty-four other neoplasms (13 leiomyosarcomas, 8 neuroblastomas, 5 lymphomas, 6 Wilms tumors without skeletal muscle differentiation, 5 Ewing sarcomas, 4 malignant fibrous histiocytomas, 4 angiosarcomas, 6 malignant melanomas, and 3 synovial sarcomas) were negative for Cav-3 expression.

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  • (PMID = 16082247.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MyoD Protein; 0 / MyoD1 myogenic differentiation protein; 0 / Myogenin
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73. Zaiden R, Latif N, Pham D, Hosenpud J: Dermatofibroma protuberans arising from an infected insect bite. Clin Adv Hematol Oncol; 2009 Jun;7(6):404-8
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  • [Title] Dermatofibroma protuberans arising from an infected insect bite.
  • [MeSH-major] Dermatofibrosarcoma / etiology. Insect Bites and Stings / complications. Skin Neoplasms / etiology. Wound Infection / complications

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  • [CommentIn] Clin Adv Hematol Oncol. 2009 Jun;7(6):406-8 [19606077.001]
  • (PMID = 19606076.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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74. Hallor KH, Sciot R, Staaf J, Heidenblad M, Rydholm A, Bauer HC, Aström K, Domanski HA, Meis JM, Kindblom LG, Panagopoulos I, Mandahl N, Mertens F: Two genetic pathways, t(1;10) and amplification of 3p11-12, in myxoinflammatory fibroblastic sarcoma, haemosiderotic fibrolipomatous tumour, and morphologically similar lesions. J Pathol; 2009 Apr;217(5):716-27
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  • To further characterize these aberrations, we have investigated eight soft tissue sarcomas diagnosed as MIFS, haemosiderotic fibrolipomatous tumour (HFT), myxoid spindle cell/pleomorphic sarcoma with MIFS features, and inflammatory malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma with prominent inflammation (IMFH) harbouring a t(1;10) or variants thereof and/or ring chromosomes with possible involvement of chromosome 3.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 10 / genetics. Chromosomes, Human, Pair 3 / genetics. Female. Gene Expression Profiling / methods. Hemosiderosis / genetics. Histiocytoma, Malignant Fibrous / genetics. Histiocytoma, Malignant Fibrous / pathology. Humans. In Situ Hybridization, Fluorescence / methods. Karyotyping. Lower Extremity. Male. Middle Aged. Oligonucleotide Array Sequence Analysis / methods. Reverse Transcriptase Polymerase Chain Reaction / methods. Ring Chromosomes. Translocation, Genetic

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  • (PMID = 19199331.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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75. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, Bonichon F, Stoeckle E, Bui NB: Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas. Cancer; 2006 Jun 15;106(12):2725-33
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  • [Title] Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas.
  • Malignant fibrous histiocytoma (MFH) is no longer considered a homogeneous entity, but rather as the common morphologic appearance of various subtypes of sarcomas.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16688768.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Keylock JB, Galvin JR, Franks TJ: Sclerosing hemangioma of the lung. Arch Pathol Lab Med; 2009 May;133(5):820-5
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  • [Title] Sclerosing hemangioma of the lung.
  • We present a brief review of sclerosing hemangioma, an uncommon but histologically distinctive neoplasm of the lung.
  • Based on immunohistochemical and molecular findings, sclerosing hemangioma is thought to be derived from incompletely differentiated respiratory epithelium.
  • Sclerosing hemangiomas typically present as asymptomatic, peripheral, solitary, well-circumscribed lesions in women with a mean age at diagnosis in the fifth decade.
  • Histologically, sclerosing hemangioma is characterized by a distinct constellation of findings including 2 epithelial cell types, surface cells and round cells, which form 4 architectural patterns, papillary, sclerotic, solid, and hemorrhagic.
  • Sclerosing hemangioma of the lung is generally considered to be a benign lesion, and surgical excision is curative without the need for additional treatment.
  • [MeSH-major] Lung / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 19415961.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 29
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77. Ding Y, Boguslawski EA, Berghuis BD, Young JJ, Zhang Z, Hardy K, Furge K, Kort E, Frankel AE, Hay RV, Resau JH, Duesbery NS: Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma. Mol Cancer Ther; 2008 Mar;7(3):648-58
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  • Similar results were obtained with cell lines derived from malignant fibrous histiocytomas, leiomyosarcomas, and liposarcomas.

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  • (PMID = 18319331.001).
  • [ISSN] 1535-7163
  • [Journal-full-title] Molecular cancer therapeutics
  • [ISO-abbreviation] Mol. Cancer Ther.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA 109308
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Bacterial; 0 / Bacterial Toxins; 0 / anthrax toxin; EC 2.7.11.24 / Mitogen-Activated Protein Kinases
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78. Tsukahara T, Kawaguchi S, Torigoe T, Asanuma H, Nakazawa E, Shimozawa K, Nabeta Y, Kimura S, Kaya M, Nagoya S, Wada T, Yamashita T, Sato N: Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5. Cancer Sci; 2006 Dec;97(12):1374-80
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  • In contrast, such prognostic significance of HLA class I expression was not found in 15 patients with malignant fibrous histiocytoma of soft tissue.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Histiocytoma, Malignant Fibrous / immunology. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / secondary. Humans. Immunoenzyme Techniques. Lymphocytes, Tumor-Infiltrating / immunology. Male. Middle Aged. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. RNA, Neoplasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Sarcoma / immunology. Sarcoma / metabolism. Sarcoma / secondary. Soft Tissue Neoplasms / immunology. Soft Tissue Neoplasms / metabolism. Soft Tissue Neoplasms / pathology. Survival Rate. T-Lymphocytes, Cytotoxic / immunology. beta 2-Microglobulin / genetics. beta 2-Microglobulin / immunology. beta 2-Microglobulin / metabolism

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  • (PMID = 16995877.001).
  • [ISSN] 1347-9032
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Histocompatibility Antigens Class I; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / beta 2-Microglobulin
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79. Antal A, Zelger B, Reifenberger J, Niehues T, Feyen O, Megahed M, Ruzicka T, Homey B: Multiple eruptive myxoid dermatofibromas: report of first case and review of literature. Br J Dermatol; 2007 Aug;157(2):382-5
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  • [Title] Multiple eruptive myxoid dermatofibromas: report of first case and review of literature.
  • Multiple eruptive dermatofibromas are a rare presentation of dermatofibroma which are frequently associated with underlying diseases such as human immunodeficiency virus infection or lupus erythematosus.
  • Eruptive dermatofibromas generally present a characteristic histology with a poorly circumscribed lesion showing hyperplasia of the epidermis, prominent bundles of collagen and a diffuse proliferation of fibrocytes.
  • We report an unusual case of multiple eruptive dermatofibromas showing massive depositions of mucin within the dermis.
  • To our knowledge this is the first report of multiple eruptive myxoid dermatofibromas.
  • We consider this case to be a unique presentation of multiple eruptive dermatofibroma showing massive deposition of mucin.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17596172.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Mucins
  • [Number-of-references] 38
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80. Marcet S: Atypical fibroxanthoma/malignant fibrous histiocytoma. Dermatol Ther; 2008 Nov-Dec;21(6):424-7
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  • [Title] Atypical fibroxanthoma/malignant fibrous histiocytoma.
  • Atypical fibroxanthoma (AFX) is an unusual spindle cell tumor occurring on actinically damaged skin of the head and neck.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Skin Neoplasms / pathology


81. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Title] Malignant fibrous histiocytoma of the conjunctiva.
  • Fibrous histiocytomas are mesenchymal tumours composed of cells with fibroblastic to histiocytic differentiation.
  • To date, there are 18 cases of fibrous histiocytoma arising from the corneoscleral limbus reported in the literature.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • Herein, the clinicopathological features of a case of malignant fibrous histiocytoma are presented and its management with wide excision and cryotherapy followed by ocular reconstruction with amniotic membrane transplant is discussed.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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82. Sutthiruangwong P, Thanakit V, Assavamongkolkul A: Angiomatoid fibrous histiocytoma with pain in a child. J Med Assoc Thai; 2005 Oct;88(10):1453-7
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  • [Title] Angiomatoid fibrous histiocytoma with pain in a child.
  • Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor with low-grade malignancy which occurs chiefly in children and young adults.
  • Clinically, the tumor appears as a cutaneous nodule with slow growth.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / complications. Pain / etiology. Soft Tissue Neoplasms / complications. Subcutaneous Tissue

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  • (PMID = 16519396.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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83. Hannachi Sassi S, Trabelsi M, Abid L, Mrad K, Abbess I, Dhouib R, Driss M, Mbarek M, Ben Romdhane K: [Deep benign fibrous histiocytoma: a case report]. Rev Chir Orthop Reparatrice Appar Mot; 2006 Dec;92(8):809-12
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  • [Title] [Deep benign fibrous histiocytoma: a case report].
  • Bening fibrous histiocytoma is one of the most frequent benign tumors.
  • Most tumors are found in the skin, particularly on the limbs.
  • According to the WHO, a deep location is found for less than 1% of all benign fibrous histiocytomas.
  • [MeSH-major] Buttocks. Histiocytoma, Benign Fibrous / diagnosis. Soft Tissue Neoplasms / diagnosis. Subcutaneous Tissue

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  • (PMID = 17245241.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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84. Ajlan AM, Sayegh K, Powell T, David H, Riha RM, Khan J, Nahal A: Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases. J Comput Assist Tomogr; 2010 Sep-Oct;34(5):791-4
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  • [Title] Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases.
  • OBJECTIVE: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor usually affecting the extremities of children and young adults and has a favorable prognosis.
  • CONCLUSIONS: Although the overall features of AFH can be confused with other subtypes of malignant fibrous histiocytoma, the young age at presentation, the location of the mass, the presence of intralesional blood-filled cystic spaces with fluid-fluid levels, associated features of hemosiderin deposition, and an enhancing fibrous pseudocapsule are all potential hints favoring this entity.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 20861788.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Yang S, Jeung HC, Jeong HJ, Choi YH, Kim JE, Jung JJ, Rha SY, Yang WI, Chung HC: Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer. Genomics; 2007 Apr;89(4):451-9
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  • The selected genes include those that were previously identified as being tumor suppressors or deleted in various tumors, including GATA binding protein 4 (GATA4), monoamine oxidase A (MAOA), cyclin C (CCNC), and oncogenes including malignant fibrous histiocytoma amplified sequence 1 (MFHAS1/MASL1), high mobility group AT-hook 2 (HMGA2), PPAR binding protein (PPARBP), growth factor receptor-bound protein 7 (GRB7), and TBC1 (tre-2, BUB2, cdc16) domain family, member 1 (TBC1D1).

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  • (PMID = 17229543.001).
  • [ISSN] 0888-7543
  • [Journal-full-title] Genomics
  • [ISO-abbreviation] Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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86. Cardinale L, Ardissone F, Familiari U, Perna M, Fava C: A case of intermittent lumbar pain radiating to the right shoulder in a 76-year-old woman. Eur Radiol; 2009 Sep;19(9):2315-9
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  • Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma, occurring most frequently in the deep soft tissues of the extremities, and it is most frequently seen in elderly patients.
  • In this report, we describe the clinical and multi-phase CT features of a primary MFH of the diaphragm.
  • [MeSH-major] Diaphragm / pathology. Histiocytoma, Malignant Fibrous / diagnostic imaging. Muscle Neoplasms / diagnostic imaging

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  • (PMID = 19626327.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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87. Puhaindran ME, Pratt J, Manoso MW, Healey JH, Mintz DN, Athanasian EA: Predictive value of magnetic resonance imaging in determining presence of residual disease after marginal excision of unsuspected soft tissue sarcomas of the hand. J Hand Surg Am; 2010 Sep;35(9):1479-84
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  • PURPOSE: Diagnosis of a soft tissue sarcoma of the hand is at times made only in retrospect after marginal excision of a presumed benign soft tissue mass.
  • RESULTS: There were 8 epithelioid sarcomas, 6 synovial sarcomas, 4 malignant fibrous histiocytomas, 2 leiomyosarcomas, 2 liposarcomas, 2 myxofibrosarcomas, and one each of 9 other diagnoses.

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  • [Copyright] Copyright 2010. Published by Elsevier Inc.
  • (PMID = 20807625.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Kanner WA, Brill LB 2nd, Patterson JW, Wick MR: CD10, p63 and CD99 expression in the differential diagnosis of atypical fibroxanthoma, spindle cell squamous cell carcinoma and desmoplastic melanoma. J Cutan Pathol; 2010 Jul;37(7):744-50
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  • BACKGROUND: Atypical fibroxanthoma (AFX) is a pleomorphic spindle cell lesion of the skin; it is considered in the differential diagnosis with spindle cell malignant melanoma (MM) and sarcomatoid carcinoma/spindle cell squamous cell carcinoma (SCC).
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Melanoma / diagnosis. Skin Neoplasms / diagnosis


89. Bharath C, Williams S: Benign fibrous histiocytoma of the nose. J Otolaryngol; 2005 Aug;34(4):253-4
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  • [Title] Benign fibrous histiocytoma of the nose.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Nose Neoplasms / diagnosis. Nose Neoplasms / pathology

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  • (PMID = 16048697.001).
  • [ISSN] 0381-6605
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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90. Schmidt JM, North SM, Freeman KP, Ramiro-Ibañez F: Canine paediatric oncology: retrospective assessment of 9522 tumours in dogs up to 12 months (1993-2008). Vet Comp Oncol; 2010 Dec;8(4):283-92
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  • [Title] Canine paediatric oncology: retrospective assessment of 9522 tumours in dogs up to 12 months (1993-2008).
  • Canine cutaneous histiocytoma (n = 8465; 89%) was the most common histological type.
  • Neoplasms other than histiocytoma (n = 1057; 11%) were grouped as benign epithelial (n = 375; 4%), haematopoietic (n = 229; 2%), benign mesenchymal (n = 145; 2%), miscellaneous (n = 118; 1%), non-hematopoietic malignant mesenchymal (n = 118; 1%) or malignant epithelial tumours (n = 72; <1%).
  • Excluding canine cutaneous histiocytoma, 52% of tumours (n = 547) were benign, and 66% were from the skin or soft tissues.
  • [MeSH-major] Aging. Dog Diseases / diagnosis. Neoplasms / veterinary

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 21062410.001).
  • [ISSN] 1476-5829
  • [Journal-full-title] Veterinary and comparative oncology
  • [ISO-abbreviation] Vet Comp Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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91. Kimyai-Asadi A, Goldberg LH, Greenberg C, Rabin V, Parry R, Batres E, Jih MH: Cellular, atypical, and indeterminate dermatofibromas: benign or malignant? Dermatol Surg; 2008 Sep;34(9):1264-71; discussion 1271-2
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  • [Title] Cellular, atypical, and indeterminate dermatofibromas: benign or malignant?
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 18554287.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Rünger TM, Quintanilla-Dieck MJ, Bhawan J: Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation. J Invest Dermatol; 2007 Feb;127(2):293-7
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  • The collagenolytic activity of cathepsin K plays a pivotal role in bone resorption and lung matrix homeostasis, but so far has not been described in skin.
  • To study the role of cathepsin K in the turnover of the cutaneous extracellular matrix, we studied the expression of cathepsin K in human skin and in cultured primary neonatal skin fibroblasts.
  • Normal skin exhibited only low levels or no expression of cathepsin K.
  • Cathepsin K was also found to be strongly expressed in keloids and dermatofibromas, but not in sclerotic areas of morphea.
  • [MeSH-minor] Cathepsin K. Cells, Cultured. Cytoplasm / enzymology. Endosomes / enzymology. Fibroblasts / enzymology. Histiocytoma, Benign Fibrous / enzymology. Humans. Infant, Newborn. Keloid / enzymology. Scleroderma, Localized / enzymology. Skin / enzymology. Staining and Labeling

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  • (PMID = 16946716.001).
  • [ISSN] 1523-1747
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.4.- / Cathepsins; EC 3.4.22.38 / CTSK protein, human; EC 3.4.22.38 / Cathepsin K
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93. Bermejo Casero E, Pérez Alonso D, Quevedo Losada S, López Rivero L: [Dermatofibroma metastasizing to the lung: current treatment]. Arch Bronconeumol; 2009 Oct;45(10):521-3
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  • [Title] [Dermatofibroma metastasizing to the lung: current treatment].
  • [Transliterated title] Dermatofibroma y metástasis pulmonares. Tratamiento actual.
  • Dermatofibromas are very common skin tumors.
  • They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm.
  • We present the case of a young woman with a recurrent dermatofibroma on the shoulder that metastasized to both lungs.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 19394746.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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94. Lin N, Urabe K, Moroi Y, Uchi H, Nakahara T, Dainichi T, Kokuba H, Tu Y, Furue M: Overexpression of phosphorylated-STAT3 and phosphorylated-ERK protein in dermatofibrosarcoma protuberans. Eur J Dermatol; 2006 May-Jun;16(3):262-5
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  • The expressions of p-STAT3 and p-ERK were analyzed by immunohistochemical staining in formalin-fixed, paraffin-embedded tissue sections of human DFSP and dermatofibroma.
  • Ten cases were positive for p-STAT3 expression in 14 cases of DFSP, however, only 5 cases were positive in 20 cases of dermatofibroma.
  • Eleven out of 14 cases of DFSP expressed p-ERK, but only four cases were positive in 20 cases of dermatofibroma.
  • The expressions of p-STAT3 and p-ERK were significantly higher than those in dermatofibroma (both p < 0.01).
  • [MeSH-major] Extracellular Signal-Regulated MAP Kinases / metabolism. Histiocytoma, Benign Fibrous / metabolism. STAT3 Transcription Factor / metabolism

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  • (PMID = 16709490.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / STAT3 Transcription Factor; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases
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95. Mandal S, Mandal AK: Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma. Int J Clin Oncol; 2007 Feb;12(1):52-5
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  • [Title] Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.
  • Malignant fibrous histiocytoma (MFH) originates from primitive mesenchymal cells and has the capacity for dual differentiation into histiocytes and fibroblasts.
  • Here we report a case of a 42-year-old man who developed MFH in his right knee over a period of more than 10 years after radio (44 Gy)-chemotherapy to treat Hodgkin's lymphoma.
  • [MeSH-major] Bone Neoplasms / etiology. Histiocytoma, Malignant Fibrous / etiology. Hodgkin Disease / therapy. Muscle Neoplasms / etiology


96. Wang SQ, Lee PK: Treatment of dermatofibroma with a 600 nm pulsed dye laser. Dermatol Surg; 2006 Apr;32(4):532-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of dermatofibroma with a 600 nm pulsed dye laser.
  • BACKGROUND: Dermatofibroma (DF) is one of the most basic and common dermatologic diseases treated by practicing dermatologists on a daily basis.
  • Although benign, it can be pruritic or tender.
  • [MeSH-major] Histiocytoma, Benign Fibrous / therapy. Laser Therapy

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  • (PMID = 16681661.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Chao HH, Tsai MF, Hung CY, Lee CH: Is wide excision sufficient as treatment for malignant fibrous histiocytomas of the trunk in children? Int Surg; 2005 Nov-Dec;90(5):305-7
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  • [Title] Is wide excision sufficient as treatment for malignant fibrous histiocytomas of the trunk in children?
  • The aim of this study was to review our experience of treatment and outcome for malignant fibrous histiocytomas (MFH) of the trunk in children.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery

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  • (PMID = 16625952.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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98. Koletsa T, Hytiroglou P, Semoglou C, Drevelegas A, Karkavelas G: Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin. Pathol Int; 2007 Aug;57(8):513-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin.
  • Angiomatoid fibrous histiocytoma is an unusual soft tissue tumor, mostly arising in the subcutaneous fibro-adipose tissue of children and young adults and measuring a few centimeters in greatest dimension.
  • Reported herein is a unique case of angiomatoid fibrous histiocytoma containing epithelium-lined cystic structures.
  • This large tumor (12 cm) was located in the subcutaneous tissue of the left leg of a 28-year-old woman.
  • The present case is illustrative of a mechanism of sweat duct dilatation that may occur during the growth of neoplasms involving the dermis and subcutis, resulting in formation of tumors with unusual histological features.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Neoplasms, Adnexal and Skin Appendage / pathology. Soft Tissue Neoplasms / pathology. Sweat Glands / pathology

  • Genetic Alliance. consumer health - Histiocytoma, angiomatoid fibrous.
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  • (PMID = 17610476.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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99. Issakov J, Kollender Y, Soyfer V, Bickels J, Flusser G, Meller I, Merimsky O: A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma. Oncol Rep; 2005 Oct;14(4):1071-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma.
  • Malignant fibrous histiocytoma (MFH) is the most common subtype of soft-tissue sarcoma (STS).
  • [MeSH-major] Extremities / pathology. Histiocytoma, Benign Fibrous / radiotherapy. Histiocytoma, Benign Fibrous / surgery. Soft Tissue Neoplasms / radiotherapy. Soft Tissue Neoplasms / surgery

  • Genetic Alliance. consumer health - Malignant fibrous histiocytoma.
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  • (PMID = 16142374.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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100. Chung TJ, Cheng L, Yu CY: Left ventricular malignant fibrous histiocytoma. Clin Imaging; 2007 Nov-Dec;31(6):422-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Left ventricular malignant fibrous histiocytoma.
  • Primary malignant fibrous histiocytoma (MFH) of the heart is rare.
  • [MeSH-major] Heart Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis

  • Genetic Alliance. consumer health - Malignant fibrous histiocytoma.
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  • (PMID = 17996607.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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