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1. Vaideeswar P: Sclerosing hemangioma with lymph nodal metastases. Indian J Pathol Microbiol; 2009 Jul-Sep;52(3):392-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing hemangioma with lymph nodal metastases.
  • A case of sclerosing hemangioma of the lung is reported in a young male, who presented with recurrent cough and streaky hemoptysis for three years.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Lymphatic Metastasis / pathology. Neoplasm Metastasis / pathology

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  • (PMID = 19679971.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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2. Guerra-Gutiérrez F, Torres Sánchez I, Gallardo-Madueño G, Mariño-Enríquez A, Nistal M: [Pulmonary sclerosing hemangioma in a patient with Cowden syndrome]. Arch Bronconeumol; 2007 Jul;43(7):418-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary sclerosing hemangioma in a patient with Cowden syndrome].
  • [Transliterated title] Hemangioma esclerosante pulmonar en un paciente con síndrome de Cowden.
  • We describe the case of an 18-year-old female with Cowden syndrome in whom a simple x-ray detected a solitary pulmonary nodule that was identified as a sclerosing hemangioma.
  • Pulmonary sclerosing hemangioma is an unusual lung neoplasm which typically presents as a solitary peripheral nodule in asymptomatic women.
  • One of the main diagnostic problems is to histologically differentiate a pulmonary sclerosing hemangioma from a papillary lung carcinoma.
  • [MeSH-major] Hamartoma Syndrome, Multiple / complications. Pulmonary Sclerosing Hemangioma / complications

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  • [ErratumIn] Arch Bronconeumol. 2007 Nov;43(11):641. Nistral, Manuel [corrected to Nistal, Manuel]
  • (PMID = 17663895.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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3. Bermejo Casero E, Pérez Alonso D, Quevedo Losada S, López Rivero L: [Dermatofibroma metastasizing to the lung: current treatment]. Arch Bronconeumol; 2009 Oct;45(10):521-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Dermatofibroma metastasizing to the lung: current treatment].
  • [Transliterated title] Dermatofibroma y metástasis pulmonares. Tratamiento actual.
  • Dermatofibromas are very common skin tumors.
  • They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm.
  • We present the case of a young woman with a recurrent dermatofibroma on the shoulder that metastasized to both lungs.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 19394746.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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4. Skoulakis CE, Papadakis CE, Datseris GE, Drivas EI, Kyrmizakis DE, Bizakis JG: Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature. Acta Otorhinolaryngol Ital; 2007 Apr;27(2):90-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature.
  • Fibrous histiocytoma is a benign tumour composed of a mixture of fibroblastic and histiocytic cells.
  • Based on the location of this tumour, fibrous histiocytoma are usually divided into cutaneous types and those involving deep tissues.
  • These lesions most often arise on the skin, but may rarely occur in soft deep tissues.
  • The diagnosis of fibrous histiocytoma may be clinically difficult when the lesion is located in the deep tissues, and is frequently confirmed after local excision.
  • The most important diagnostic distinction is the separation of this tumour from aggressive forms of fibrohistiocytic neoplasms, including dermatofibrosarcoma protuberans and malignant fibrous histiocytoma.
  • The lesion had been totally excised under local anaesthesia, and histopathology revealed a benign fibrous histiocytoma.
  • The diagnosis, location, treatment and prognosis of fibrous histiocytoma are also discussed.
  • [MeSH-major] Cheek / pathology. Histiocytoma, Benign Fibrous / pathology

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  • [Cites] J Cutan Pathol. 2000 Jan;27(1):36-9 [10660130.001]
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  • (PMID = 17608138.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC2640009
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5. Lang KJ, Lidder S, Hofer M, Graham C, Taylor A: Rapidly evolving giant dermatofibroma. Case Rep Med; 2010;2010:620910

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapidly evolving giant dermatofibroma.
  • Dermatofibroma, also known as "fibrous histiocytoma", is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis.
  • Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature.
  • We present a case of a rapidly evolving pedunculated mass in the groin of a male patient.
  • Histological examination confirmed this to be a giant dermatofibroma.
  • Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases.
  • The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion.

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  • [Cites] Clin Adv Hematol Oncol. 2009 Jun;7(6):404-8 [19606076.001]
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  • (PMID = 20224764.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2836174
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6. Demir MK, Ozdemir H, Gençhallaç H, Altaner S, Kartal O: Dermatofibroma mimicking malignancy on integrated F-18 fluorodeoxyglucose PET-CT. Diagn Interv Radiol; 2009 Mar;15(1):61-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma mimicking malignancy on integrated F-18 fluorodeoxyglucose PET-CT.
  • The PET-CT demonstrated focal nodular uptake in the subcutaneous tissue of the back adjacent to the paraspinal muscles.
  • The pathologic diagnosis was dermatofibroma.
  • Although benign, dermatofibromas can have intense FDG uptake.
  • [MeSH-major] Fluorodeoxyglucose F18. Histiocytoma, Benign Fibrous / radionuclide imaging. Positron-Emission Tomography / methods. Radiopharmaceuticals. Skin Neoplasms / radionuclide imaging

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  • (PMID = 19263377.001).
  • [ISSN] 1305-3612
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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7. de Koning DB, Drenth JP, Oyen WJ, Wagenaar M, Aliredjo RP, Nagengast FM: Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case. Dis Colon Rectum; 2007 Nov;50(11):1987-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case.
  • This lesion was found to be a sclerosing hemangioma.
  • We found an aberrant beta-catenin expression on immunohistochemical staining, suggesting that sclerosing hemangioma and familial adenomatous polyposis share the same pathophysiology.
  • It is important to be aware of the association of familial adenomatous polyposis and sclerosing hemangioma.
  • [MeSH-major] Adenomatous Polyposis Coli / epidemiology. Positron-Emission Tomography. Pulmonary Sclerosing Hemangioma / epidemiology

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  • (PMID = 17473941.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / beta Catenin; 40871-47-4 / 2-fluoro-2-deoxyglucose-6-phosphate; 56-73-5 / Glucose-6-Phosphate
  • [Other-IDs] NLM/ PMC3234159
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8. Nonaka D: A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). Histopathology; 2008 Jun;52(7):896-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Dendritic Cells / metabolism. Histiocytoma, Benign Fibrous / pathology. Monocytes / metabolism. Skin Neoplasms / pathology

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  • (PMID = 18462367.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.3.2.13 / Factor XIIIa
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9. Keylock JB, Galvin JR, Franks TJ: Sclerosing hemangioma of the lung. Arch Pathol Lab Med; 2009 May;133(5):820-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing hemangioma of the lung.
  • We present a brief review of sclerosing hemangioma, an uncommon but histologically distinctive neoplasm of the lung.
  • Based on immunohistochemical and molecular findings, sclerosing hemangioma is thought to be derived from incompletely differentiated respiratory epithelium.
  • Sclerosing hemangiomas typically present as asymptomatic, peripheral, solitary, well-circumscribed lesions in women with a mean age at diagnosis in the fifth decade.
  • Histologically, sclerosing hemangioma is characterized by a distinct constellation of findings including 2 epithelial cell types, surface cells and round cells, which form 4 architectural patterns, papillary, sclerotic, solid, and hemorrhagic.
  • Sclerosing hemangioma of the lung is generally considered to be a benign lesion, and surgical excision is curative without the need for additional treatment.
  • [MeSH-major] Lung / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 19415961.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 29
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10. Komatsu T, Fukuse T, Wada H, Sakurai T: Pulmonary sclerosing hemangioma with pulmonary metastasis. Thorac Cardiovasc Surg; 2006 Aug;54(5):348-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary sclerosing hemangioma with pulmonary metastasis.
  • We present a case of pulmonary sclerosing hemangioma with multiple involvements.
  • Pulmonary sclerosing hemangioma is a relatively rare neoplasm.
  • Although it is thought to be benign, cases with lymph node metastasis or multiple pulmonary involvement have been reported in clinical settings.
  • To date, no case has been reported with mortality due to sclerosing hemangioma, however its clinical characteristics of multiple spread and lymphnode metastasis have not yet been elucidated.
  • [MeSH-major] Lung Neoplasms / secondary. Neoplasms, Multiple Primary / pathology. Pulmonary Sclerosing Hemangioma / secondary

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  • (PMID = 16902885.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Latif MJ, Rahman GF, Connery CP: Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus. J Bronchology Interv Pulmonol; 2009 Jul;16(3):188-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Respiratory arrest caused by endobronchial sclerosing hemangioma of the left main bronchus.
  • Sclerosing hemangioma is a rare pulmonary tumor that usually grows as a peripheral intraparenchymal lesion in the lungs.
  • Although some case series have described this rare tumor, endobronchial growth of sclerosing hemangioma is extremely rare, with only 3 reported cases in the literature to date.

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  • (PMID = 23168550.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Einsfelder BM, Müller KM: ["Pneumocytoma" or "sclerosing hemangioma": histogenetic aspects of a rare tumor of the lung]. Pathologe; 2005 Sep;26(5):367-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] ["Pneumocytoma" or "sclerosing hemangioma": histogenetic aspects of a rare tumor of the lung].
  • [Transliterated title] "Pneumozytom" oder "sklerosierendes Hämangiom". Histogenetische Aspekte zu einem seltenen Lungentumor.
  • Aspects of histogenesis and nomenclature of so called "sclerosing hemangioma" of the lung (WHO 1999) are discussed and compared with immunohistochemical findings in eight examined operation specimen.
  • Therefore, this rare usually benign pulmonary neoplasm should be entitled "pneumocytoma" analogous to the suggestion of several other authors.
  • [MeSH-major] Lung Neoplasms / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 15731902.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 41
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13. Bougrine F, Chouchane O, Doghri R, Znaidi N, Hchicha S, Sakhri A, Laabidi B, Cheikh R, Chnik S, Bouziani A: [Sclerosing hemangioma of the lung: a rare lesion with a difficult diagnosis]. Rev Pneumol Clin; 2006 Dec;62(6 Pt 1):390-4
Genetic Alliance. consumer health - Hemangioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sclerosing hemangioma of the lung: a rare lesion with a difficult diagnosis].
  • [Transliterated title] L'hémangiome sclérosant du poumon: une lésion rare et de diagnostic difficile.
  • Sclerosing hemangioma of the lung is a rare lesion described for the first time in 1956 by Liebow.
  • Surgical resection enabled the histopathological diagnosis of sclerosing hemangioma.
  • [MeSH-major] Lung / pathology. Pulmonary Sclerosing Hemangioma / diagnosis

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  • (PMID = 17242645.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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14. Katakura H, Sato M, Tanaka F, Sakai H, Bando T, Hasegawa S, Nakashima Y, Wada H: Pulmonary sclerosing hemangioma with metastasis to the mediastinal lymph node. Ann Thorac Surg; 2005 Dec;80(6):2351-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary sclerosing hemangioma with metastasis to the mediastinal lymph node.
  • During a routine health care evaluation, an abnormal shadow was detected in the chest roentgenogram of a 35-year-old man.
  • Then, left lower lobectomy was performed, and the tumor was diagnosed as a pulmonary sclerosing hemangioma.
  • As lymph node metastasis from pulmonary sclerosing hemangioma is very rare, we herein report the details of our case.
  • [MeSH-major] Pulmonary Sclerosing Hemangioma / secondary

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  • (PMID = 16305908.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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15. Anan E, Shirai R, Hirat N, Nakam K, Ushijima C, Kadota J: [Two cases, of pulmonary sclerosing hemangioma, and peripheral lung carcinoid, in which the diagnoses were difficult by intraoperative frozen section examinations]. Nihon Kokyuki Gakkai Zasshi; 2010 Mar;48(3):253-9
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  • [Title] [Two cases, of pulmonary sclerosing hemangioma, and peripheral lung carcinoid, in which the diagnoses were difficult by intraoperative frozen section examinations].
  • Case 1: A 38-year-old man was referred to our hospital because of a chest nodular shadow found on a medical check-up.
  • However, the postoperative histopathological diagnosis was pulmonary sclerosing hemangioma with lymph node metastasis.
  • Case 2: An 81-year-old woman was referred to our hospital because of a chest nodular shadow found on a medical check-up.
  • These cases suggest that it may be difficult to diagnose peripheral lung carcinoid or pulmonary sclerosing hemangioma by intraoperative frozen section examination because of their pathological diversity.
  • [MeSH-major] Carcinoid Tumor / pathology. Frozen Sections. Histiocytoma, Malignant Fibrous / pathology. Lung Neoplasms / pathology

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  • (PMID = 20387533.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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16. Kasper B, Ouali M, Van Glabbeke M, Blay J, Bramwell VH, Woll PJ, Schöffski P: Prognostic factors in adolescents and young adults (AYA) with high-risk soft tissue sarcoma (STS) treated by adjuvant chemotherapy: A study based on two pooled European Organisation for Research and Treatment of Cancer (EORTC) clinical trials. J Clin Oncol; 2009 May 20;27(15_suppl):10573

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  • The variables of the multivariate analysis were gender, subtype and grade, tumor size and localization (limb vs. other), absence or presence of local recurrence and treatment (control arm vs. adjuvant chemotherapy).
  • RESULTS: Patients' characteristics were globally similar with two exceptions, histological subtype (p = 0.0043) and tumor size (p < .0001).
  • The commonest sarcoma subtype in the AYA population was synovial sarcoma (29 %), whereas leiomyosarcoma (18 %), malignant fibrous histiocytoma (MFH, 16 %) and liposarcoma (15 %) were more frequent in patients ≥ 30 years.
  • For OS, independent favorable prognostic factors were low grade and small tumor size for both groups; radical resection and MFH or liposarcoma subtype were factors of favorable prognosis for patients ≥ 30 years only.

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  • (PMID = 27963782.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Moreno-Vega A, Chavarría N, Rubio J, Villandiego I, Estepa R, Gordon M, Salvador J, Jimenez E: Primary breast sarcoma: Clinical and retrospective analysis of cases from Jerez General Hospital, Spain. J Clin Oncol; 2009 May 20;27(15_suppl):e21526

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  • We analysed diseases outcomes (disease free survival, DFS) by histology high risk factors (tumor size, histology, and proliferation index).
  • RESULTS: Seven cases of PBS (1 male/6 female) were reviewed, from 790 BC diagnosed (0.8%): 2 angiosarcomas (AS), 1 malignant fibrous histiocytoma, 2 undifferentiated, one osteoclastic and other spindle-cell sarcoma.

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  • (PMID = 27963456.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Pedro Boléo-Tomé J, Matos C, Nogueira F, Maya M, Sena Lino J, Cancela de Abreu M: [A rare case of multiple sclerosing hemangiomas of the lung]. Rev Port Pneumol; 2008 Mar-Apr;14(2):291-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A rare case of multiple sclerosing hemangiomas of the lung].
  • [Transliterated title] Um caso raro de hemangioma esclerosante múltiplo do pulmão.
  • Sclerosing hemangioma of the lung is an uncommon benign tumour which usually presents as an asymptomatic solitary nodule.
  • The authors describe a case of a 50 year-old asymptomatic woman with multiple nodular lesions involving all the lobes of both lungs, which underwent diagnostic thoracotomy after thorough investigation to exclude extra-pulmonary neoplasia.
  • The biopsies obtained led to the diagnosis of pulmonary sclerosing hemangiomas.
  • [MeSH-major] Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 18363024.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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19. Wani Y, Notohara K, Tsukayama C, Okumura N: Sclerosing hemangioma with florid endobronchial and endobronchiolar growth. Virchows Arch; 2007 Feb;450(2):221-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing hemangioma with florid endobronchial and endobronchiolar growth.
  • Sclerosing hemangioma (SH) with endobronchial growth (SH-EG) is an extremely unusual form of SH.
  • [MeSH-major] Bronchi / pathology. Histiocytoma, Benign Fibrous / pathology

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  • [Cites] Respirology. 1999 Dec;4(4):401-4 [10612575.001]
  • [Cites] Am J Surg Pathol. 2000 Jul;24(7):906-16 [10895813.001]
  • [Cites] Mod Pathol. 2004 Feb;17(2):252-7 [14704717.001]
  • [Cites] Am J Surg Pathol. 1984 Nov;8(11):845-54 [6507723.001]
  • [Cites] Gan No Rinsho. 1989 Jun;35(7):840-4 [2661882.001]
  • (PMID = 17120028.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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20. Jungraithmayr W, Eggeling S, Ludwig C, Kayser G, Passlick B: Sclerosing hemangioma of the lung: a benign tumour with potential for malignancy? Ann Thorac Cardiovasc Surg; 2006 Oct;12(5):352-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing hemangioma of the lung: a benign tumour with potential for malignancy?
  • Pulmonary sclerosing hemangioma represents a rare neoplasm with variable potential for progression.
  • This case report of a 35-year-old female with left-sided thoracic pain.
  • Intraoperative findings were suggestive of a carcinoid tumour.
  • The histopathological analysis revealed a sclerosing hemangioma, a rare benign neoplasm.
  • Sclerosing hemangiomas (SHs) are true neoplasms derived from alveolar pneumocytes.
  • [MeSH-major] Pneumonectomy / methods. Pulmonary Sclerosing Hemangioma / diagnosis

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  • (PMID = 17095978.001).
  • [ISSN] 1341-1098
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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21. Neuman J, Rosioreanu A, Schuss A, Turi G, Yung E, Trow TK, Williams L, Katz DS: Radiology-pathology conference: sclerosing hemangioma of the lung. Clin Imaging; 2006 Nov-Dec;30(6):409-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiology-pathology conference: sclerosing hemangioma of the lung.
  • Sclerosing hemangioma (SH) is a relatively rare, benign neoplasm of the lung.
  • We report the radiology and pathology of a patient with a SH, with emphasis on the computed tomographic and (18)F-fluorodeoxyglucose positron emission tomography findings, and review the literature on this unusual tumor.
  • [MeSH-major] Fluorodeoxyglucose F18. Lung / radiography. Lung / radionuclide imaging. Positron-Emission Tomography / methods. Pulmonary Sclerosing Hemangioma / diagnosis. Tomography, X-Ray Computed / methods

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  • (PMID = 17101410.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 18
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22. Sartori G, Bettelli S, Schirosi L, Bigiani N, Maiorana A, Cavazza A, Rossi G: Microsatellite and EGFR, HER2 and K-RAS analyses in sclerosing hemangioma of the lung. Am J Surg Pathol; 2007 Oct;31(10):1512-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microsatellite and EGFR, HER2 and K-RAS analyses in sclerosing hemangioma of the lung.
  • Sclerosing hemangioma (SH) is an uncommon pulmonary tumor thought to derive from primitive respiratory epithelium consisting of 2 cell populations (cuboidal surface and polygonal stromal cells) and sharing some clinical characteristics (frequent occurrence in nonsmoking women of Asian ethnicity) with bronchioloalveolar carcinoma with which it has been suggested a possible common origin.
  • [MeSH-major] Adenocarcinoma / genetics. Microsatellite Repeats. Proto-Oncogene Proteins p21(ras) / genetics. Pulmonary Sclerosing Hemangioma / genetics. Receptor, Epidermal Growth Factor / genetics. Receptor, ErbB-2 / genetics

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  • (PMID = 17895751.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / ERBB2 protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras)
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23. Aydin E, Vardareli OS, Bilezikçi B, Ozgirgin ON: [Dermatofibroma accompanied by perforating dermatosis in the auricle: a case report]. Kulak Burun Bogaz Ihtis Derg; 2005;15(3-4):83-6
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  • [Title] [Dermatofibroma accompanied by perforating dermatosis in the auricle: a case report].
  • [Transliterated title] Aurikulada dermatofibroma eşlik eden perforan dermatoz: Olgu sunumu.
  • Although dermatofibroma is one of the most common soft tissue tumors, it is rarely seen in the face.
  • Total excisional biopsy was performed, which showed dermatofibroma accompanied by perforating dermatosis.
  • Our literature search did not yield any reported case of dermatofibroma accompanied by perforating dermatosis.
  • [MeSH-major] Dermatitis / diagnosis. Ear, External / pathology. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16340298.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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24. Córdoba S, Hernández A, Romero A, Arias D, Castaño E, García-Donoso C, Borbujo JM: [Basal cell carcinoma overlying a dermatofibroma]. Actas Dermosifiliogr; 2005 Nov;96(9):612-5
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  • [Title] [Basal cell carcinoma overlying a dermatofibroma].
  • [Transliterated title] Carcinoma basocelular sobre dermatofibroma.
  • The epidermis over a dermatofibroma may show changes that range from simple hyperplasia to the proliferation of basaloid cells, which can become morphologically indistinguishable from basal cell carcinoma.
  • The existence of a true basal cell carcinoma overlying a dermatofibroma is infrequent.
  • These basaloid proliferations have usually been considered to be the result of the inductive effect of the fibrohistiocytic proliferation of the dermatofibroma on the epithelial cells of the hair follicle; therefore, it would be a reactive phenomenon and not truly neoplastic.
  • We describe a case of dermatofibroma that presented with a basaloid proliferation identical in appearance to a basal cell carcinoma on the overlying epidermis.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Histiocytoma, Benign Fibrous / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476308.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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25. Amin RM, Hiroshima K, Miyagi Y, Kokubo T, Hoshi K, Fujisawa T, Nakatani Y: Role of the PI3K/Akt, mTOR, and STK11/LKB1 pathways in the tumorigenesis of sclerosing hemangioma of the lung. Pathol Int; 2008 Jan;58(1):38-44
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  • [Title] Role of the PI3K/Akt, mTOR, and STK11/LKB1 pathways in the tumorigenesis of sclerosing hemangioma of the lung.
  • Although the histogenesis of sclerosing hemangioma (SH) of the lung is now thought to be respiratory epithelial in origin, the genetic abnormalities that mediate its development are not known.
  • Because pathophysiology of several syndromes associated with benign tumors may converge on the tuberous sclerosis complex (TSC), serine/threonine kinase 11 (STK11), and mammalian target of rapamycin (mTOR) pathways, the purpose of the present paper was to investigate their roles in the development of SH.
  • [MeSH-major] Protein Kinases / metabolism. Protein-Serine-Threonine Kinases / genetics. Pulmonary Sclerosing Hemangioma / genetics. Pulmonary Sclerosing Hemangioma / metabolism. Signal Transduction / physiology

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  • (PMID = 18067639.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] EC 2.7.- / Protein Kinases; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.1.- / STK11 protein, human; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt
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26. Kalhor N, Staerkel GA, Moran CA: So-called sclerosing hemangioma of lung: current concept. Ann Diagn Pathol; 2010 Feb;14(1):60-7
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  • [Title] So-called sclerosing hemangioma of lung: current concept.
  • Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features.
  • Herein, we present a review of sclerosing hemangioma and summarize the essential data regarding histologic, cytologic, and ancillary findings of this distinctive pulmonary neoplasm.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Pulmonary Sclerosing Hemangioma / metabolism. Pulmonary Sclerosing Hemangioma / pathology

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20123460.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 41
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27. Boudaya MS, Falcoz PE, Alifano M, Camilleri-Broet S, Régnard JF: Endobronchial sclerosing hemangioma: a rare presentation of a parenchymal tumor. Asian Cardiovasc Thorac Ann; 2008 Jan;16(1):57-8
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  • [Title] Endobronchial sclerosing hemangioma: a rare presentation of a parenchymal tumor.
  • Endobronchial localization of sclerosing hemangioma is extremely rare.
  • We report a case of endobronchial sclerosing hemangioma diagnosed preoperatively and treated by lingular-sparing upper lobectomy with nodal dissection.
  • [MeSH-major] Bronchial Neoplasms / pathology. Incidental Findings. Pulmonary Sclerosing Hemangioma / pathology. Solitary Pulmonary Nodule / pathology

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  • (PMID = 18245708.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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28. Wei S, Tian J, Song X, Chen Y: Recurrence of pulmonary sclerosing hemangioma. Thorac Cardiovasc Surg; 2008 Mar;56(2):120-2
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  • [Title] Recurrence of pulmonary sclerosing hemangioma.
  • Pathological examination confirmed it to be a pulmonary sclerosing hemangioma.
  • Pathological examination once again confirmed the diagnosis of sclerosing hemangioma.
  • However, the recurrence of pulmonary sclerosing hemangioma is very rare; thus, we report here on one clinical case in detail.
  • [MeSH-major] Neoplasm Recurrence, Local. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 18278694.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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29. Oishi H, Kawamura M, Hoshi F, Hasumi T, Saito Y: [The fluorodeoxyglucose-positron emission tomography (FDG-PET) findings and surgical strategy for pulmonary sclerosing hemangioma]. Kyobu Geka; 2010 Aug;63(9):769-73
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  • [Title] [The fluorodeoxyglucose-positron emission tomography (FDG-PET) findings and surgical strategy for pulmonary sclerosing hemangioma].
  • The pulmonary sclerosing hemangioma is a comparatively rare lung tumor.
  • We operated on 7 patients of the pulmonary sclerosing hemangioma during January, 2009 from December, 2001.
  • We thought that the findings of FDG-PET reflected proliferation potency of the pulmonary sclerosing hemangioma.
  • The clinical features of the pulmonary sclerosing hemangioma are various.
  • [MeSH-major] Fluorodeoxyglucose F18. Histiocytoma, Benign Fibrous / radionuclide imaging. Histiocytoma, Benign Fibrous / surgery. Lung Neoplasms / radionuclide imaging. Lung Neoplasms / surgery. Radiopharmaceuticals

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  • (PMID = 20715456.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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30. Chung MJ, Lee KS, Han J, Sung YM, Chong S, Kwon OJ: Pulmonary sclerosing hemangioma presenting as solitary pulmonary nodule: dynamic CT findings and histopathologic comparisons. AJR Am J Roentgenol; 2006 Aug;187(2):430-7
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  • [Title] Pulmonary sclerosing hemangioma presenting as solitary pulmonary nodule: dynamic CT findings and histopathologic comparisons.
  • OBJECTIVE: The purpose of this study was to describe the dynamic CT findings of pulmonary sclerosing hemangioma presenting as a solitary pulmonary nodule and to compare these findings with histopathologic findings.
  • CONCLUSION: On dynamic CT, sclerosing hemangioma has strong and rapid enhancement attributed histopathologically to the presence of hemangiomatous or papillary components in the tumor.
  • [MeSH-major] Pulmonary Sclerosing Hemangioma / pathology. Pulmonary Sclerosing Hemangioma / radiography. Solitary Pulmonary Nodule / pathology. Solitary Pulmonary Nodule / radiography. Tomography, X-Ray Computed

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  • (PMID = 16861548.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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31. Hanaoka J, Ohuchi M, Inoue S, Sawai S, Tezuka N, Fujino S: Bilateral multiple pulmonary sclerosing hemangioma. Jpn J Thorac Cardiovasc Surg; 2005 Mar;53(3):157-61
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  • [Title] Bilateral multiple pulmonary sclerosing hemangioma.
  • We present herein a rare case of bilateral pulmonary sclerosing hemangioma, for which a differential diagnosis was made from metastatic lung tumors.
  • The tumors, measuring 16x13x12 mm in the left lung and 27x24x20 mm in the right lung, were resected, and then pathological examination confirmed the diagnosis of sclerosing hemangioma.
  • [MeSH-major] Pneumonectomy / methods. Pulmonary Sclerosing Hemangioma / pathology. Pulmonary Sclerosing Hemangioma / surgery

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  • [Cites] Jpn J Clin Oncol. 1986 Mar;16(1):77-86 [3009921.001]
  • [Cites] Ann Thorac Surg. 2002 Mar;73(3):981-3 [11899220.001]
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  • (PMID = 15828298.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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32. Miura N, Shoji F, Kawano D, Morodomi Y, Ito K, Yano T, Maehara Y: A pulmonary sclerosing hemagioma with an increasing uptake on PET. Thorac Cardiovasc Surg; 2009 Dec;57(8):498-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A pulmonary sclerosing hemagioma with an increasing uptake on PET.
  • Pulmonary sclerosing hemangioma is a relatively rare neoplasm of the lung.
  • Although there have been five previous case reports that address the 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) findings in a sclerosing hemangioma of the lung, no report has demonstrated an interval change in the FDG-PET findings.
  • This report describes a case of pulmonary sclerosing hemangioma which presented with an increase of uptake of FDG-PET after about one years' follow-up.
  • [MeSH-major] Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography. Pulmonary Sclerosing Hemangioma / radionuclide imaging

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  • [Copyright] Copyright Georg Thieme Verlag KG Stuttgart . New York.
  • (PMID = 20013629.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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33. Rognstad ØB, Haas N, Sterry W, Astner S: Multiple clustered dermatofibroma with overlying sebaceous hyperplasia. J Dtsch Dermatol Ges; 2009 Nov;7(11):962-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple clustered dermatofibroma with overlying sebaceous hyperplasia.
  • Multiple clustered dermatofibroma is a very rare clinical variant of the dermatofibroma, and sebaceous differentiation overlying dermatofibromas is also unusual.
  • We report the first case of a multiple clustered dermatofibroma with overlying sebaceous hyperplasia.
  • [MeSH-major] Histiocytoma, Benign Fibrous / complications. Histiocytoma, Benign Fibrous / pathology. Neoplasms, Multiple Primary / complications. Neoplasms, Multiple Primary / pathology. Sebaceous Gland Diseases / complications. Sebaceous Gland Diseases / pathology. Skin Neoplasms / pathology

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  • (PMID = 19538483.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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34. Hueso L, Sanmartín O, Alfaro-Rubio A, Serra-Guillén C, Martorell A, Llombart B, Requena C, Nagore E, Botella-Estrada R, Guillén C: [Giant dermatofibroma: case report and review of the literature]. Actas Dermosifiliogr; 2007 Mar;98(2):121-4
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  • [Title] [Giant dermatofibroma: case report and review of the literature].
  • [Transliterated title] Dermatofibroma gigante: descripción de un caso y revisión de la literatura.
  • Dermatofibroma is a very frequent lesion that usually appears as a slowly growing nodule in the dermis, and preferentially involves the lower extremities of women.
  • Giant dermatofibroma has been defined as a rare variant of dermatofibroma measuring more than 5 cm that presents typical histological features and a benign biological behavior.
  • We report the case of a 52-year-old man that presented a giant dermatofibroma with a diameter of 6 cm in the right shoulder and we review the few cases of this variant that have been described in the literature.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17397601.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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35. Garrido-Ruiz MC, Ramos P, Enguita AB, Rodriguez Peralto JL: Subcutaneous atypical fibrous histiocytoma. Am J Dermatopathol; 2009 Jul;31(5):499-501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous atypical fibrous histiocytoma.
  • Benign fibrous histiocytoma is one of the most frequent benign neoplasms mainly composed of a mixture of fibroblastic and histiocytic cells, especially found in the skin (dermatofibroma), particularly in the limbs.
  • The diagnosis of cutaneous benign fibrous histiocytoma is generally easy; however, rare variants may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination.
  • Thus, deep subcutaneous dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans and dermatofibroma with monster giant cells from malignant fibrous histiocytoma and atypical fibroxanthoma.
  • We report a case of a 38-year-old woman with a painless swelling on the abdominal wall, which was totally excised and histopathologically diagnosed as subcutaneous atypical fibrous histiocytoma.
  • The lesion was deeply located within the subcutaneous tissue and consisted of interlacing fascicles of predominant histiocyte-like spindle cells intermingled with pleomorphic giant cells with bizarre large nuclei (bilobed and multilobed) and prominent eosinophilic nucleoli.
  • Recognition of dermatofibroma is important, allowing sequential excision and optimal results.
  • To the best of our knowledge, we report the first case of subcutaneous fibrous histiocytoma with monster cells.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19542931.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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36. Tran TA, Hayner-Buchan A, Jones DM, McRorie D, Carlson JA: Cutaneous balloon cell dermatofibroma (fibrous histiocytoma). Am J Dermatopathol; 2007 Apr;29(2):197-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous balloon cell dermatofibroma (fibrous histiocytoma).
  • Dermatofibroma (DF) or cutaneous fibrous histiocytoma is a common benign skin tumor that exhibits multiple, distinct histologic variants.
  • Herein, we describe the clinicopathologic findings of balloon cell DF arising on the heel of a 43-year-old man.
  • Excisional biopsy revealed a circumscribed fibrous tumor populated by mostly clear and spindle cells.
  • DF with balloon cell change, likely secondary to persistent irritation, should be added to the differential diagnosis of cutaneous primary and metastatic neoplasms showing balloon cell degeneration such as balloon cell melanocytic nevi and renal cell carcinoma, respectively.
  • [MeSH-major] Heel. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17414448.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; EC 2.3.2.13 / Factor XIIIa; EC 3.4.24.11 / Neprilysin
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37. Choi KH, Baek HA, Park HS, Jang KY, Jin GY, Kim MH, Lee YC, Moon WS, Chung MJ: Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung. Pathol Int; 2008 Nov;58(11):735-40
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  • [Title] Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung.
  • Pulmonary sclerosing hemangioma is generally considered a rare neoplasm presenting as a solitary benign nodule.
  • During routine medical examination multiple abnormal nodular shadows were detected in the right lower lung field on chest X-ray in a 48-year-old asymptomatic woman.
  • All of these lesions had typical features of sclerosing hemangioma.
  • The authors call this unusual growth pattern of sclerosing hemangioma a 'pneumonic pattern'.
  • [MeSH-major] Adenoma / pathology. Pulmonary Sclerosing Hemangioma / pathology

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  • (PMID = 18844941.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1
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38. Pareja MJ, Vargas MT, Sánchez A, Ibáñez J, González-Cámpora R: Cytogenetic study of a pulmonary sclerosing hemangioma. Cancer Genet Cytogenet; 2009 Nov;195(1):80-4
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  • [Title] Cytogenetic study of a pulmonary sclerosing hemangioma.
  • Pulmonary sclerosing hemangioma (PSH) is an uncommon benign tumor that presents as a solitary asymptomatic and slow-growing nodule.
  • We report a case of pulmonary sclerosing hemangioma in a 61-year-old woman with a neoplastic node 1 cm in diameter.
  • These chromosome abnormalities could provide information about the relationship of genetic changes to the biological properties of sclerosing hemangioma tumors.
  • [MeSH-major] Pulmonary Sclerosing Hemangioma / genetics

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  • (PMID = 19837274.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Yamamoto T, Sumi K, Yokozeki H, Nishioka K: Multiple cutaneous fibrous histiocytomas in association with systemic lupus erythematosus. J Dermatol; 2005 Aug;32(8):645-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple cutaneous fibrous histiocytomas in association with systemic lupus erythematosus.
  • Cutaneous fibrous histiocytomas are usually regarded as superficial lesions and commonly known as dermatofibromas; however, unusual cases histologically showing fibrohistiocytic proliferation extending into the deeper dermis or subcutaneous tissues are occasionally experienced.
  • Some authors propose this type as benign fibrous histiocytoma of the skin, distinct from dermatofibroma.
  • The nodule on the forehead did not present a typical clinical appearance of dermatofibroma, and histopathological examination showed fibrohistiocytic proliferation with a storiform pattern extending into the deep dermis and subcutaneous tissues.
  • By contrast, histology of the nodule on the abdomen showed fibrohistiocytic proliferation confined to the dermis and compatible with dermatofibroma.
  • Although multiple dermatofibromas are occasionally seen in patients with SLE, benign fibrous histiocytoma of the skin showing deeper invasion than dermatofibroma is rarely associated with SLE.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Lupus Erythematosus, Systemic. Skin Neoplasms / diagnosis


40. Yoo SH, Jung KC, Kim JH, Sung SW, Chung JH, Shim YS, Lee SD, Chung DH: Expression patterns of markers for type II pneumocytes in pulmonary sclerosing hemangiomas and fetal lung tissues. Arch Pathol Lab Med; 2005 Jul;129(7):915-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression patterns of markers for type II pneumocytes in pulmonary sclerosing hemangiomas and fetal lung tissues.
  • CONTEXT: Although the histogenesis of sclerosing hemangioma is currently not well understood, the tumor has been characterized by its 2 histologically different types of cells, namely, surface and polygonal cells.
  • OBJECTIVE: To elucidate the origin of these cells, we analyzed samples from 15 cases of sclerosing hemangioma and 15 specimens of fetal lung tissue.
  • DESIGN: We immunostained specimens from 15 cases of sclerosing hemangioma and 15 samples of fetal lung tissue using antibodies against thyroid transcription factor 1, MUC1, Thomsen-Friedenreich antigen, and CD44v6, known as markers for type II pneumocytes, and a panel of antibodies against cytokeratin, epithelial membrane antigen, synaptophysin, CD56, estrogen receptor, and progesterone receptor.
  • MUC1, thyroid transcription factor 1, and epithelial membrane antigen were observed in both surface and polygonal cells of sclerosing hemangioma.
  • Only the surface cells in all cases of sclerosing hemangioma showed positivity for cytokeratin and CD44v6.
  • Thomsen-Friedenreich antigen was expressed in the surface cells of 11 of 15 cases of sclerosing hemangioma.
  • CONCLUSIONS: Our results suggest that the 2 types of cells in sclerosing hemangioma may derive from a common precursor cell through divergent differentiation toward the type II pneumocyte during tumorigenesis.
  • [MeSH-major] Fetus / metabolism. Gene Expression Profiling / methods. Gene Expression Regulation, Developmental / genetics. Gene Expression Regulation, Neoplastic / genetics. Genetic Markers / genetics. Lung / metabolism. Pulmonary Sclerosing Hemangioma / classification

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  • (PMID = 15974816.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens; 0 / Antigens, CD44; 0 / Antigens, Neoplasm; 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / CD44v6 antigen; 0 / Genetic Markers; 0 / Glycoproteins; 0 / MUC1 protein, human; 0 / Mucin-1; 0 / Mucins; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1; 3554-90-3 / Thomsen-Friedenreich antigen
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41. Spaun E, Zelger B: Dermatofibroma with intracytoplasmic eosinophilic globules: an unusual phenomenon. J Cutan Pathol; 2009 Jul;36(7):796-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma with intracytoplasmic eosinophilic globules: an unusual phenomenon.
  • Dermatofibroma (DF) is a very common lesion of the skin and presents in many guises that might cause problems in differential diagnosis.
  • [MeSH-major] Cytoplasmic Granules / pathology. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology

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  • [Copyright] (c) 2009 John Wiley & Sons A/S.
  • (PMID = 19519612.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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42. González-Vilas D, García-Gavín J, Ginarte M, Rodríguez-Blanco I, Toribio J: Ulcerated dermatofibroma with osteoclast-like giant cells. J Cutan Pathol; 2009 Oct;36 Suppl 1:16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ulcerated dermatofibroma with osteoclast-like giant cells.
  • BACKGROUND: Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas.
  • METHODS: We report the clinical, histopathological and immunohistochemical findings of a 38-year-old man with an ulcerated dermatofibroma (DF) on the sole containing OLGC.
  • COMMENTS: DF, or cutaneous fibrous histiocytoma, is a frequent dermatological lesion with many clinicopathological variants.
  • Differential diagnosis was performed with cutaneous and even non-cutaneous lesions.
  • [MeSH-major] Foot Diseases / pathology. Foot Ulcer / pathology. Giant Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19775390.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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43. Baines SJ, McInnes EF, McConnell I: E-cadherin expression in canine cutaneous histiocytomas. Vet Rec; 2008 Apr 19;162(16):509-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] E-cadherin expression in canine cutaneous histiocytomas.
  • Canine cutaneous histiocytoma is a common skin tumour of Langerhans cell origin.
  • The expression of E-cadherin by the neoplastic Langerhans cells in 37 dogs with cutaneous histiocytoma was studied by flow cytometry and immunohistochemistry.
  • [MeSH-major] Cadherins / analysis. Dog Diseases / immunology. Histiocytoma, Benign Fibrous / veterinary. Langerhans Cells / immunology. Skin Neoplasms / veterinary

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  • [CommentIn] Vet Rec. 2008 Jul 12;163(2):59-60; author reply 60 [18622005.001]
  • (PMID = 18424847.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Cadherins
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44. Suzuki K, Shiono S, Kato H, Yanagawa N, Sato T: [Small sclerosing hemangioma combined with primary lung cancer; report of a case]. Kyobu Geka; 2006 Jul;59(7):590-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Small sclerosing hemangioma combined with primary lung cancer; report of a case].
  • In February 2002, computed tomography (CT) was performed as a part of a follow-up study and showed 2 small nodules in the lower lobe of her right lung: one was 10 mm nodule in S9, and another was 5 mm in S6.
  • In contrast, the nodule in S6 had not enlarged and it was thought to be benign.
  • The S9 nodule was diagnosed as adenocarcinoma, and the S6 nodule as sclerosing hemangioma.
  • [MeSH-major] Adenocarcinoma / radiography. Lung Neoplasms / radiography. Neoplasms, Multiple Primary. Pneumonectomy. Pulmonary Sclerosing Hemangioma / radiography

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  • (PMID = 16856537.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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45. Sachdev R, Sundram U: Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa. J Cutan Pathol; 2006 May;33(5):353-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa.
  • BACKGROUND: Distinction between cellular fibrous histiocytomas (FHs) with a deep component and dermatofibrosarcoma protuberans (DFSPs) can pose diagnostic problems.
  • Our goal is to evaluate the utility of CD163 in the diagnosis of dermatofibromas (DFs), cellular FHs, and DFSPs.
  • Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa.
  • [MeSH-major] Antigens, CD / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. Biomarkers, Tumor / analysis. Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Receptors, Cell Surface / biosynthesis. Skin Neoplasms / diagnosis

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  • (PMID = 16640542.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD163 antigen; 0 / CD68 antigen, human; 0 / Receptors, Cell Surface; EC 2.3.2.13 / Factor XIIIa
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46. Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J, Puig S: Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients. Br J Dermatol; 2006 Feb;154(2):244-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients.
  • BACKGROUND: The clinical diagnosis of dermatofibroma is commonly easy.
  • However, the differentiation of dermatofibroma from other cutaneous tumours is difficult in some instances, primarily in atypical cases and rare variants.
  • Haemosiderotic dermatofibroma is a variant composed of numerous small vessels, extravasated erythrocytes and intra- and extracellular haemosiderin deposits.
  • Aneurysmal dermatofibroma is a variant composed of large, blood-filled spaces without endothelial lining.
  • Some authors consider that haemosiderotic dermatofibroma is an early stage in the development of aneurysmal dermatofibroma.
  • The clinical differential diagnosis of haemosiderotic or aneurysmal dermatofibroma must include melanoma and other melanocytic tumours, vascular neoplasms, adnexal tumours and nonspecific cysts.
  • Dermoscopy improves the diagnostic accuracy in pigmented and nonpigmented skin lesions.
  • METHODS: Dermoscopic examination (using the DermLite Foto; 3Gen, LLC, Dana Point, CA, U.S.A.) of six patients with haemosiderotic or aneurysmal dermatofibromas was performed to evaluate specific dermoscopic criteria.
  • CONCLUSIONS: This dermoscopic pattern yielded the diagnosis of haemosiderotic or aneurysmal dermatofibroma in most cases.
  • However, this multicomponent pattern may present in some melanomas and although it is useful in determining a clinical diagnosis of aneurysmal dermatofibroma, it may not be specific to this entity.
  • [MeSH-major] Dermoscopy. Hemosiderin / analysis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • [CommentIn] Br J Dermatol. 2007 Jan;156(1):199-200 [17199605.001]
  • (PMID = 16433792.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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47. Smati B, Ismail O, Boudaya MS, Baccari S, Djilani H, Mestiri T, El Mezni F, Gharbi L, Kilani T: [Huge benign lung tumor in a female smoker]. Rev Pneumol Clin; 2005 Dec;61(6):379-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Huge benign lung tumor in a female smoker].
  • [Transliterated title] Tumeur de 5 cm chez une femme fumeuse.
  • Pulmonary sclerosing hemangioma is a rare, slow-growing, benign tumor.
  • Search for a cause was negative.
  • Intraoperative pathology analysis revealed the benign nature of the tumor.
  • The final pathological conclusion was sclerosing hemangioma of the lung.
  • Pulmonary sclerosing hemangioma is a parenchymal tumor of the lung.
  • [MeSH-major] Pulmonary Sclerosing Hemangioma / surgery. Smoking / adverse effects

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  • (PMID = 16449928.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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48. Garrido-Ruiz MC, Carrillo R, Enguita AB, Peralto JL: Signet-ring cell dermatofibroma. Am J Dermatopathol; 2009 Feb;31(1):84-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Signet-ring cell dermatofibroma.
  • Dermatofibroma or cutaneous fibrous histiocytoma is a common benign skin lesion with multiple, distinct histologic variants, including cellular, aneurismal, epithelioid, atypical, lipidized "ankle-type," palisading, and cholesterotic.
  • Although dermatofibromas are considered benign neoplasms, certain variants including cellular and aneurismal ones have shown to have a notable tendency to locally recur after excision.
  • The finding of signet-ring cells in a skin neoplasm always raises the suspicion of metastatic adenocarcinoma, although a number of reports have shown their occurrence in primitive cutaneous neoplasms as well.
  • Signet-ring cell formation, however, has never been described in dermatofibroma.
  • We present, for the first time, a new, distinctive variant of dermatofibroma, so-called signet-ring cell dermatofibroma, in a 16-year-old man with a slowly growing skin tumor on the lateral side of his right leg.
  • Histochemical and immunohistochemical stainings confirmed the diagnosis of dermatofibroma.
  • The phenomenon described in this case enlarges the histologic spectrum of cutaneous fibrous histiocytoma and may cause substantial differential diagnostic problems.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19155733.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Venkataraman G, Hammadeh R: Report of an angiosarcoma mimic: cutaneous aneurysmal fibrous histiocytoma. APMIS; 2006 Oct;114(10):744-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Report of an angiosarcoma mimic: cutaneous aneurysmal fibrous histiocytoma.
  • Aneurysmal fibrous histiocytoma is an unusual variant of the spectrum of fibrous histiocytomas with the peculiar morphologic appearance of a benign aneurysmal vasoformative process that ultimately culminates in multiple microhemorrhages within the tumor.
  • It looks strikingly different from the usual cutaneous lesions encountered in clinical dermatology practice.
  • A single report of a cutaneous aneurysmal fibrous histiocytoma in the skin of the back of a 60-year-old male is described with emphasis on the immunostaining pattern and review of the literature.
  • There is a significant potential for confusion of this lesion with other cutaneous lesions, clinically as well as pathologically.
  • In our case, the patient presented with a lesion that clinically resembled a hemangioma, was pathologically interpreted initially to be an angiosarcoma, and finally, the revised pathology was interpreted as an aneurysmal variant of a fibrous histiocytoma.
  • Caution is warranted to avoid misinterpretation of cutaneous fibrohistiocytic tumors.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17004978.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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50. Kwinter J, DeKoven J: Generalized eruptive histiocytoma treated with isotretinoin. J Cutan Med Surg; 2009 May-Jun;13(3):146-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Generalized eruptive histiocytoma treated with isotretinoin.
  • BACKGROUND: Generalized eruptive histiocytoma (GEH) is a rare, benign non-Langerhans cell histiocytosis characterized by widespread and symmetric skin-colored to blue-red papules on the trunk and proximal extremities affecting mainly adults.
  • [MeSH-major] Dermatologic Agents / administration & dosage. Histiocytoma, Benign Fibrous / drug therapy. Isotretinoin / administration & dosage. Skin Neoplasms / drug therapy

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  • (PMID = 19426623.001).
  • [ISSN] 1203-4754
  • [Journal-full-title] Journal of cutaneous medicine and surgery
  • [ISO-abbreviation] J Cutan Med Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dermatologic Agents; EH28UP18IF / Isotretinoin
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51. Adler N, Tsabari C, Sulkes J, Ad-El D, Feinmesser M: Cyclooxygenase-2 expression in dermatofibroma and dermatofibrosarcoma protuberans. J Cutan Pathol; 2008 Jun;35(6):532-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cyclooxygenase-2 expression in dermatofibroma and dermatofibrosarcoma protuberans.
  • BACKGROUND: Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) occasionally resemble each other histologically but differ in histogenesis and biological behavior.
  • [MeSH-major] Cyclooxygenase 2 / metabolism. Dermatofibrosarcoma / enzymology. Histiocytoma, Benign Fibrous / enzymology. Skin Neoplasms / enzymology

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  • (PMID = 18201240.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 1.14.99.1 / Cyclooxygenase 2
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52. Brown JA, Morgan MB: Pedunculated hemangiopericytoma-like tumor: peculiar fibroepithelial polyp or fibrous histiocytoma variant. J Cutan Pathol; 2008 Aug;35(8):748-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pedunculated hemangiopericytoma-like tumor: peculiar fibroepithelial polyp or fibrous histiocytoma variant.
  • Apropos of this concern, we present a series of three cutaneous polypoid lesions that simulated fibroepithelial polyp, yet upon close scrutiny yielded histologic features of solitary fibrous tumor (SFT) or hemangiopericytoma.
  • These findings were discordant with SFT and suggest a relationship with fibrous histiocytoma.
  • We propose that this entity represents a hitherto described variant of fibrous histiocytoma known as pedunculated hemangiopericytoma-like fibrous histiocytoma.
  • [MeSH-major] Hemangiopericytoma / pathology. Histiocytoma, Benign Fibrous / pathology. Polyps / pathology. Skin Neoplasms / pathology

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  • (PMID = 18422978.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2; EC 2.3.2.13 / Factor XIIIa
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53. Agero AL, Taliercio S, Dusza SW, Salaro C, Chu P, Marghoob AA: Conventional and polarized dermoscopy features of dermatofibroma. Arch Dermatol; 2006 Nov;142(11):1431-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conventional and polarized dermoscopy features of dermatofibroma.
  • OBJECTIVE: To evaluate dermoscopic features and patterns of dermatofibromas using conventional and polarized light dermoscopy.
  • DESIGN: Dermatofibromas were imaged using conventional nonpolarized contact dermoscopy (NPD), polarized contact dermoscopy (PCD), and polarized noncontact dermoscopy, followed by evaluation and comparison of dermoscopic features of the lesions.
  • Patients Fifty patients with dermatofibromas.
  • RESULTS: The most common features of dermatofibromas observed with NPD and PCD were central white scarlike patches (37 [74%] and 42 [84%], respectively), brown globulelike structures (21 [42%] and 22 [44%]), vascular structures (24 [48%] and 22 [44%]), and a peripheral fine pigmented network (36 [72%] for both).
  • The most common pattern identified with NPD and PCD was the combination of a peripheral pigmented network and a central white patch in 28 (56%) and 31 (62%) of lesions, respectively.
  • These new criteria can aid in the diagnosis of dermatofibroma.
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17116833.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] United States
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54. González-Vela MC, Val-Bernal JF, Martino M, González-López MA, García-Alberdi E, Hermana S: Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma. Histol Histopathol; 2005 07;20(3):801-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerotic fibroma-like dermatofibroma: an uncommon distinctive variant of dermatofibroma.
  • Dermatofibroma (DF) is a common benign cutaneous tumor with many variants based on alterations in the morphology and composition of its diverse elements.
  • One very infrequent type is sclerotic fibroma-like DF (SF-DF).
  • [MeSH-major] Fibroma / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15944929.001).
  • [ISSN] 0213-3911
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, CD99; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Vimentin
  • [Number-of-references] 21
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55. Shuweiter M, Böer A: Spectrum of follicular and sebaceous differentiation induced by dermatofibroma. Am J Dermatopathol; 2009 Dec;31(8):778-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spectrum of follicular and sebaceous differentiation induced by dermatofibroma.
  • BACKGROUND: The term "induction" has been used to designate epidermal changes above dermatofibroma.
  • Whereas follicular differentiation has been reported frequently, sebaceous hyperplasia above dermatofibroma is considered a rarity.
  • OBJECTIVE: To characterize all changes overlying dermatofibroma and to determine their frequency.
  • METHODS: Sections cut from 210 consecutive examples of dermatofibroma were stained with hematoxylin and eosin and analyzed for the presence or absence of induction, for the type of change induced, and for features associated with these findings.
  • RESULTS: The epidermis above dermatofibromas was acanthotic, simulating seborrheic keratosis in 62.9% of the cases, and areas of clear and pale cells similar to those of clear cell acanthoma were seen in 18.6%.
  • In 4%, formation of a complete hair follicle was encountered.
  • In 16.7% of the dermatofibromas, induction of sebaceous lobules was encountered, whereas sebaceous differentiation in the form of mantles was seen in 25.7% of the cases.
  • [MeSH-major] Hair Follicle / pathology. Histiocytoma, Benign Fibrous / pathology. Sebaceous Glands / pathology. Skin Neoplasms / pathology

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  • (PMID = 19955877.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Davis TT, Calilao G, Fretzin D: Sebaceous hyperplasia overlying a dermatofibroma. Am J Dermatopathol; 2006 Apr;28(2):155-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous hyperplasia overlying a dermatofibroma.
  • Epithelial changes overlying dermatofibromas are well recognized.
  • The presence of sebaceous differentiation overlying a dermatofibroma is unusual.
  • We report two patients with sebaceous hyperplasia overlying a dermatofibroma and discuss possible mechanisms for induction of the epithelium and adnexa by the mesenchyme in a dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Sebaceous Glands / pathology. Skin Neoplasms / pathology

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  • (PMID = 16625080.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
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57. Hamel J, Burgdorf WH, Bräuninger W: The man behind the eponym: Hans Biberstein and follicular hyperplasia overlying dermatofibroma. Am J Dermatopathol; 2009 Oct;31(7):710-4

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  • [Title] The man behind the eponym: Hans Biberstein and follicular hyperplasia overlying dermatofibroma.
  • Hans Biberstein first described the basaloid follicular hyperplasia overlying dermatofibromas in 1923 and published his extensive observations on the subject in 1931.
  • We suggest Biberstein's sign as an appropriate term for basaloid follicular hyperplasia overlying a dermatofibroma and as a small tribute to a pioneer dermatopathologist.
  • [MeSH-major] Dermatology / history. Histiocytoma, Benign Fibrous / history. Histiocytoma, Benign Fibrous / pathology. Pathology / history
  • [MeSH-minor] History, 20th Century. Hyperplasia. Skin Neoplasms / pathology

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  • (PMID = 19633531.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article
  • [Publication-country] United States
  • [Personal-name-as-subject] Biberstein H
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58. Scalvenzi M, Balato A, De Natale F, Francia MG, Mignogna C, De Rosa G: Hemosiderotic dermatofibroma: report of one case. Dermatology; 2007;214(1):82-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemosiderotic dermatofibroma: report of one case.
  • Dermatofibroma (DF) is a common benign fibrohistiocytic lesion which presents with a wide variety of clinicopathological features.
  • Generally, the clinical diagnosis is easy, but differentiating it from other cutaneous tumors could be difficult in atypical cases and rare variants.
  • We report the case of a 38-year-old man who presented with a hemosiderotic DF on the abdomen.
  • [MeSH-major] Hemosiderosis / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 17191053.001).
  • [ISSN] 1018-8665
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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59. Aggarwal K, Gupta S, Jain VK, Sen R, Gupta S: Generalized eruptive histiocytoma. Indian Dermatol Online J; 2010 Jul;1(1):27-9

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  • [Title] Generalized eruptive histiocytoma.
  • The clinical and histopathological findings were compatible with the diagnosis of generalized eruptive histiocytoma.

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  • [Cites] Clin Exp Dermatol. 1990 Nov;15(6):454-6 [2177688.001]
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  • (PMID = 23130189.001).
  • [ISSN] 2229-5178
  • [Journal-full-title] Indian dermatology online journal
  • [ISO-abbreviation] Indian Dermatol Online J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3481406
  • [Keywords] NOTNLM ; Histiocytoma / elderly male / histioctytosis
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60. Fujimura T, Okuyama R, Terui T, Okuno K, Masu A, Masu T, Chiba S, Kunii T, Tagami H, Aiba S: Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. J Cutan Pathol; 2005 Aug;32(7):512-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases.
  • Myxofibrosarcoma or myxoid malignant fibrous histiocytoma is one of the most common fibroblastic sarcomas in older patients.
  • It is characterized by a tendency for predominantly subcutaneous, multinodular, diffusely infiltrative growth, which may extend to the overlying dermis and present as a cutaneous lesion.
  • Histologically, it comprises a spectrum ranging from hypocellular low-grade myxoid to high-grade pleomorphic sarcoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16008697.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucins
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61. Pongpudpunth M, Keady M, Mahalingam M: Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis? J Cutan Pathol; 2009 Oct;36(10):1083-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis?
  • BACKGROUND: The etiopathogenesis of dermatofibroma (DF), a common benign fibrohistiocytic tumor, is debatable.
  • [MeSH-major] Elastic Tissue / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19615002.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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62. Chaâbouni S, Ayadi L, Masmoudi A, Dhouib M, Méziou J, Dammak A, Charfi S, Gouiaa N, Turki H, Abdelmoula M, Boudawara T: [Retroauricular dermatofibroma in a child simulating a malignant tumour]. Arch Pediatr; 2008 Mar;15(3):283-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Retroauricular dermatofibroma in a child simulating a malignant tumour].
  • [Transliterated title] Dermatofibrome rétro-auriculaire chez un enfant simulant une tumeur maligne.
  • BACKGROUND: Dermatofibroma represents one of the commonest benign soft tissue tumours, and its diagnosis is usually straightforward if classical clinicopathologic features are evident.
  • We report a peculiar case of an aggressive cellular dermatofibroma in a child that simulated a malignant tumour.
  • It was nodular, erythematous, infiltrating the underlying tissue with an anterior spread leading to an amputation of the auricular lobule and a retraction of the tragus.
  • The lesion had the full microscopic characteristics of a cellular dermatofibroma.
  • CONCLUSION: Dermatofibroma is one of the major differential diagnosis of nodular cutaneous tumours in children that simulate malignancy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18325746.001).
  • [ISSN] 0929-693X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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63. Vázquez-Blanco M, Peteiro C, Toribio J: [Generalized eruptive histiocytoma]. Actas Dermosifiliogr; 2006 Jan-Feb;97(1):35-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Generalized eruptive histiocytoma].
  • [Transliterated title] Histiocitoma eruptivo generalizado.
  • We present the case of a 64-year-old male who developed multiple asymptomatic papules over a four-month period, distributed symmetrically on the trunk and proximal regions of the limbs, while the scalp, palms, soles and mucous membranes were spared.
  • Clinical, histopathological, immunohistochemical and ultrastructural studies were consistent with generalized eruptive histiocytoma.
  • Generalized eruptive histiocytoma belongs to a spectrum of diseases that may overlap; some may even develop into others.
  • [MeSH-major] Histiocytoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 16540049.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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64. Nair V, Weinreb I, MacNeil N, Szollosi Z, Chetty R, Ghazarian D: A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". Eur J Dermatol; 2008 May-Jun;18(3):332-6
MedlinePlus Health Information. consumer health - Skin Cancer.

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  • [Title] A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma".
  • Dermatofibromas (cutaneous fibrous histiocytomas) are common cutaneous neoplasms of mesenchymal origin.
  • There have been reports of a spectrum of melanocytic lesions associated with dermatofibromas ranging from junctional nevi to malignant melanomas, some of which may be coincidentally associated.
  • We report a case of a long-standing storiform fibrohistiocytic lesion devoid of cytological atypia, lacking extension into subcutaneous fat, not demonstrating the t(17;22) DFSP translocation yet showing diffuse and strong CD34 immunoreactivity and containing pigmented spindle shaped melanocytic cells admixed with the fibrohistiocytic component.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 18474466.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa
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65. Bandarchi B, Ma L, Marginean C, Hafezi S, Zubovits J, Rasty G: D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans. Mod Pathol; 2010 Mar;23(3):434-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans.
  • The distinction between dermatofibroma, particularly cellular variant, and dermatofibrosarcoma protuberans in excisional biopsies is usually straightforward.
  • Although factor XIIIa and CD34 immunostains are useful in differentiating dermatofibroma and dermatofibrosarcoma protuberans in most instances, focal CD34 positivity may be seen in cellular fibrous histiocytoma.
  • In this study, we investigated the utility of D2-40 in separating dermatofibroma from dermatofibrosarcoma protuberans and compared the results with other commonly used immunostains.
  • Fifty-six cases of dermatofibroma (including six cellular variant) and 29 cases of dermatofibrosarcoma protuberans were retrieved from the archives of Department of Anatomic Pathology at Sunnybrook Health Sciences Center in University of Toronto.
  • All 56 (100%) cases of dermatofibroma demonstrated strong and diffuse immunoreactivity to D2-40 in the spindle cells and stroma.
  • Nearly all dermatofibromas were negative for CD34 except one case revealing focal positivity.
  • None of dermatofibrosarcoma protuberans cases were labeled by D2-40, although four cases showed weak and patchy background staining in contrary to diffuse, strong, and crisp staining seen in dermatofibromas.
  • Our results indicate that D2-40 seems to be a sensitive immunohistochemical marker for dermatofibromas, including cellular variant.
  • [MeSH-major] Antibodies, Monoclonal / analysis. Biomarkers, Tumor / analysis. Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis

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  • (PMID = 20062007.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40; EC 2.3.2.13 / Factor XIIIa
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66. Arpaia N, Cassano N, Vena GA: Dermoscopic patterns of dermatofibroma. Dermatol Surg; 2005 Oct;31(10):1336-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermoscopic patterns of dermatofibroma.
  • BACKGROUND: Clinical and dermoscopic aspects of dermatofibroma (DF) are usually typical.
  • [MeSH-major] Dermoscopy. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 16188191.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Murdzhev K, Uchikov A, Zaprianov Z, Dimitrov I: [A case or operative treatment of a rare lung tumor (sclerosing haemangioma)]. Khirurgiia (Sofiia); 2007;(4):68-70
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  • [Title] [A case or operative treatment of a rare lung tumor (sclerosing haemangioma)].
  • Sclerosing hemangioma of the lung is a rare tumor, defined as benign, but it has the propensity for recurrence and metastases.
  • We present a case of operative treatment of a 37-years-old female patient with such tumor, with preoperatively assessed clinical and X-ray evidence for tumor formation in the right lung.
  • Histological examination (including immunohistochemistry) showed sclerosing hemangioma (papillary pneumocytoma).
  • [MeSH-major] Lung Neoplasms / surgery. Pulmonary Sclerosing Hemangioma / surgery

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  • (PMID = 18443540.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Bulgaria
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68. Fujikawa T, Shiono S, Abiko M, Kanauchi N, Uchino H, Kim C, Shimanuki T: [Pulmonary schwannoma with hypervascularity; report of a case]. Kyobu Geka; 2008 Nov;61(12):1075-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pulmonary schwannoma with hypervascularity; report of a case].
  • The tumor was suspected to be a sclerosing hemangioma or malignant tumor.

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  • (PMID = 19048912.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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69. Sachdev R, Robbins J, Kohler S, Vanchinathan V, Schwartz EJ, Sundram UN: CD163 expression is present in cutaneous histiocytomas but not in atypical fibroxanthomas. Am J Clin Pathol; 2010 Jun;133(6):915-21
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD163 expression is present in cutaneous histiocytomas but not in atypical fibroxanthomas.
  • Our aim was to test the ability of CD163 to separate cutaneous histiocytomas from their morphologic mimics.
  • We tested the expression of CD163 in 78 cases, including 19 xanthogranulomas, 16 atypical fibroxanthomas, 6 reticulohistiocytomas, 8 epithelioid cell histiocytomas, 9 cases of Langerhans cell histiocytosis, 10 xanthomas, and 10 intradermal Spitz nevi.
  • CD163 expression was seen in all xanthogranulomas and reticulohistiocytomas, 4 epithelioid cell histiocytomas, 2 cases of Langerhans cell histiocytosis, and 8 xanthomas but was absent in atypical fibroxanthomas and Spitz nevi.
  • CD163 is an excellent marker for confirming histiocytic differentiation and is useful in eliminating morphologic mimics such as Spitz nevi from the differential diagnosis.
  • [MeSH-major] Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Biomarkers, Tumor / immunology. Histiocytoma, Benign Fibrous / chemistry. Histiocytoma, Benign Fibrous / immunology. Receptors, Cell Surface / analysis. Skin Neoplasms / immunology

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  • (PMID = 20472850.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD163 antigen; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Receptors, Cell Surface; 0 / Receptors, Scavenger; EC 3.4.24.11 / Neprilysin
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70. Sabah M, Cummins R, Leader M, Kay E: Leiomyosarcoma and malignant fibrous histiocytoma share similar allelic imbalance pattern at 9p. Virchows Arch; 2005 Mar;446(3):251-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leiomyosarcoma and malignant fibrous histiocytoma share similar allelic imbalance pattern at 9p.
  • The specimens consisted of 17 cases of soft tissue leiomyosarcoma (LMS), 4 cases of cutaneous LMS, 22 cases of conventional malignant fibrous histiocytoma (MFH) and 2 cases of angiomatoid fibrous histiocytoma.
  • Alterations of this locus were very rare in synovial sarcoma and malignant peripheral nerve sheath tumours and were absent in cutaneous LMS and angiomatoid fibrous histiocytoma.
  • This locus may point to the existence of a genetically altered tumour suppressor gene involved in the pathogenesis of LMS and MFH.
  • [MeSH-major] Chromosomes, Human, Pair 9 / genetics. DNA, Neoplasm / genetics. Histiocytoma, Benign Fibrous / genetics. Leiomyosarcoma / genetics. Soft Tissue Neoplasms / genetics

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  • (PMID = 15731925.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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71. Kovach BT, Boyd AS: Melanoma associated with a dermatofibroma. J Cutan Pathol; 2007 May;34(5):420-2
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanoma associated with a dermatofibroma.
  • BACKGROUND: Dermatofibromas are common benign cutaneous fibrohistiocytic neoplasms, whereas melanomas are potentially aggressive malignancies.
  • METHODS: We report the case of a 56-year-old female presenting with a firm pink papule on the left thigh.
  • The atypical melanocytes stained for MART-1 and S-100, whereas the underlying fibrohistiocytic tumor took up factor XIIIa immunostain, confirming the diagnosis of invasive malignant melanoma occurring in association with a dermatofibroma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17448199.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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72. Gershtenson PC, Krunic AL, Chen HM: Multiple clustered dermatofibroma: case report and review of the literature. J Cutan Pathol; 2010 Sep;37(9):e42-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple clustered dermatofibroma: case report and review of the literature.
  • The presence of multiple dermatofibromas is rare and is defined as more than 15 lesions.
  • Multiple clustered dermatofibroma (MCDF) is a distinct entity with only 12 reported cases in the literature.
  • On histology, MCDF is consistent with benign dermatofibromas.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 19614987.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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73. Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M: High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors. Arch Pathol Lab Med; 2006 Jun;130(6):831-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors.
  • CONTEXT: Dermatofibroma is a benign fibrohistiocytic tumor composed of a mixture of fibroblastic and histiocytic cells.
  • Deep penetrating dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans, and pseudosarcomatous dermatofibroma and dermatofibroma with monster giant cells share morphologic similarities with malignant fibrous histiocytoma and atypical fibroxanthoma.
  • OBJECTIVE: To find an immunohistochemical marker or markers that differentiate between fibrohistiocytic lesions of skin.
  • DESIGN: We evaluated the immunophenotypic characteristics of 83 fibrohistiocytic tumors (36 typical dermatofibromas, 16 cases of dermatofibrosarcoma protuberans, 16 malignant fibrous histiocytomas, and 15 atypical fibroxanthomas) using antibodies against MIB-1 (Ki-67), factor XIIIa, CD34 (HPCA-1), HHF35 (muscle-specific actin), 1A4 (smooth muscle actin), cytokeratin (AE1/AE3, CAM 5.2, and 34betaE12), S100 protein, and desmin.
  • RESULTS: A high proliferative index detected by MIB-1 staining excluded the possibility of dermatofibroma and was diagnostically useful in separating this entity from dermatofibrosarcoma protuberans, malignant fibrous histiocytoma, and atypical fibroxanthoma.
  • A low proliferative index, however, could not differentiate dermatofibroma from dermatofibrosarcoma protuberans.
  • Factor XIIIa reactivity was not helpful for the diagnosis of dermatofibroma, whereas CD34 reactivity was statistically significant in the diagnosis of dermatofibrosarcoma protuberans.
  • CONCLUSION: Evaluation of the proliferative index may further assist in distinguishing dermatofibroma from dermatofibrosarcoma protuberans, atypical fibroxanthoma, and malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Ki-67 Antigen / metabolism. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Biopsy. Cell Nucleus / metabolism. Cell Nucleus / pathology. Cell Proliferation. Dermatofibrosarcoma / pathology. Diagnosis, Differential. Fluorescent Antibody Technique, Indirect. Histiocytoma, Malignant Fibrous / pathology. Humans. Immunoenzyme Techniques. Xanthomatosis / pathology

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  • [CommentIn] Arch Pathol Lab Med. 2008 Feb;132(2):160; author reply 160-1 [18251566.001]
  • (PMID = 16740036.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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74. Giovani P, Patrikidou A, Ntomouchtsis A, Meditskou S, Thuau H, Vahtsevanos K: Benign fibrous histiocytoma of the buccal mucosa: case report and literature review. Case Rep Med; 2010;2010:306148

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign fibrous histiocytoma of the buccal mucosa: case report and literature review.
  • Benign fibrous histiocytoma is an interesting and challenging entity even in its most usual, cutaneous presentation.

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  • (PMID = 20589214.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2892663
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75. Yamamoto T: Dermatofibroma: a possible model of local fibrosis with epithelial/mesenchymal cell interaction. J Eur Acad Dermatol Venereol; 2009 Apr;23(4):371-5
Genetic Alliance. consumer health - Dermatofibroma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatofibroma: a possible model of local fibrosis with epithelial/mesenchymal cell interaction.
  • Dermatofibromas are benign dermal nodules usually seen on the extremities; however, whether a dermatofibroma is a reactive fibrous hyperplasia or a true neoplasm is still unclear.
  • Fibrous type dermatofibromas might be regarded as the symptom of local fibrotic processes and thus present a possible model of local fibrosis.
  • Interaction between proliferated dermatofibroma fibroblasts and overlying elongated epidermis suggests a relationship between keratinocytes and mesenchymal cells.
  • We herein describe current insights into the pathogenesis of dermatofibromas and explore the possible involvement of immunocytes around fibroblasts and effector cells which play an important role in the development of dermatofibromas.
  • [MeSH-major] Epithelial Cells / pathology. Fibrosis / pathology. Histiocytoma, Benign Fibrous / pathology. Mesoderm / pathology. Models, Biological

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  • (PMID = 19175704.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 54
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76. Gu M, Sohn K, Kim D, Kim B: Metastasizing dermatofibroma in lung. Ann Diagn Pathol; 2007 Feb;11(1):64-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasizing dermatofibroma in lung.
  • Benign dermatofibroma is very common skin tumor and can very rarely metastasize.
  • We report a case of metastasizing dermatofibroma on a 36-year-old woman who presented multiple bilateral lung nodules.
  • She underwent incisional biopsy for cellular dermatofibroma of the right shoulder 7 years ago.
  • The lung mass shows same histologic features with skin lesion.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 17240311.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; EC 3.4.24.11 / Neprilysin
  • [Number-of-references] 7
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77. Rawal YB, Kalmar JR, Shumway B, Mallery SR: Presentation of an epithelioid cell histiocytoma on the ventral tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Jul;100(1):75-83
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  • [Title] Presentation of an epithelioid cell histiocytoma on the ventral tongue.
  • The epithelioid cell histiocytoma (ECH) is a polypoidal benign tumor of superficial connective tissue that is often diagnosed as a pyogenic granuloma.
  • Although dendritic subunits are distributed throughout most collagenous tissues inclusive of oral mucosa, to date, all reported cases of ECH have been cutaneous lesions.
  • Consistent with its benign course, the ECH is managed by local excision, and has an excellent prognosis.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Tongue Neoplasms / pathology

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  • (PMID = 15953920.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD31; 0 / Antigens, CD34; 68238-35-7 / Keratins; EC 2.3.2.13 / Factor XIIIa
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78. Frau DV, Erdas E, Caria P, Ambu R, Dettori T, Faa G, Fletcher CD, Vanni R: Deep fibrous histiocytoma with a clonal karyotypic alteration: molecular cytogenetic characterization of a t(16;17)(p13.3;q21.3). Cancer Genet Cytogenet; 2010 Oct 1;202(1):17-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep fibrous histiocytoma with a clonal karyotypic alteration: molecular cytogenetic characterization of a t(16;17)(p13.3;q21.3).
  • Deep fibrous histiocytoma, a rare lesion occuring in deep soft tissues, has recently been formally characterized as a diagnostically distinguishable variant of the benign fibrous histiocytoma spectrum with distinct morphological features.
  • We report a 46,XY,t(16;17)(p13.3;q21.3) karyotype in a deep fibrous histiocytoma.
  • No break-apart signals were observed in the six additional cases studied, indicating either that the translocation is sporadic or that it is rare in deep fibrous histiocytoma.
  • In conclusion, our data show that chromosome aberrations may be found in deep fibrous histiocytoma and that, as with cutaneous lesions, they may have clonal, at present nonrecurrent, chromosome changes.
  • [MeSH-major] Chromosomes, Human, Pair 16. Chromosomes, Human, Pair 17. Histiocytoma, Benign Fibrous / genetics. Karyotyping / methods. Translocation, Genetic

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20804915.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Vimentin
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79. Gonzalez S: Apocrine gland cyst with hemosiderotic dermatofibroma-like stroma: report of two cases. Am J Dermatopathol; 2005 Feb;27(1):36-8
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  • [Title] Apocrine gland cyst with hemosiderotic dermatofibroma-like stroma: report of two cases.
  • Two cases of an unusual cutaneous lesion characterized by a dermal nodule with apocrine gland cysts surrounded by a hemosiderotic dermatofibroma-like proliferating stroma are reported.
  • The cystic spaces consisted of ductal structures and a bilayered epithelial covering with apocrine differentiation; the surrounding area showed a stroma composed of a mixture of both fibrocytes and macrophages and abundant hemosiderin granules; foci of recent hemorrhages and a more dense fibrous stroma at the periphery with typical storiform areas were also visible.
  • Both cases have shown a benign course without local recurrence in follow up until this report date.
  • [MeSH-major] Apocrine Glands / pathology. Epidermal Cyst / pathology. Hemosiderin / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 15677975.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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80. Kuroda K, Tajima S: Proliferation of HSP47-positive skin fibroblasts in dermatofibroma. J Cutan Pathol; 2008 Jan;35(1):21-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proliferation of HSP47-positive skin fibroblasts in dermatofibroma.
  • BACKGROUND: The cell origin of dermatofibroma (DF) has not been clarified satisfactorily.
  • This study was undertaken to assess the distribution of fibroblasts and the relationship between fibroblasts and other constituent cells in DF by 47-kDa heat-shock protein (HSP47), a cell marker for skin fibroblast.
  • CONCLUSIONS: Skin fibroblast is one of the major constituent cells in DF, and DF may be composed chiefly of two types of cell lineages, fibroblasts and bone marrow-derived monocyte/macrophages (dermal dendritic cells and/or histiocytes).
  • [MeSH-major] Fibroblasts / metabolism. HSP47 Heat-Shock Proteins / metabolism. Histiocytoma, Benign Fibrous / metabolism. Skin / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 18095990.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD68 antigen, human; 0 / HSP47 Heat-Shock Proteins; 0 / SERPINH1 protein, human; EC 2.3.2.13 / Factor XIIIa
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81. Quigley BC, Ricciuti J, Morgan MB: Amyloid light chain deposition associated with dermatofibroma: serendipity or association? Am J Dermatopathol; 2010 May;32(3):298-300
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  • [Title] Amyloid light chain deposition associated with dermatofibroma: serendipity or association?
  • Primary cutaneous amyloidosis, also known as nodular amyloidosis, is defined as deposition of amyloid light chain in the skin in the absence of a systemic cause of amyloidosis.
  • In contrast, secondary cutaneous amyloidosis is related to lesions such as squamous cell carcinoma, Bowen disease, basal cell carcinoma, and discoid lupus erythematosus, and has been shown in most cases to be derived from keratin epithelial elements.
  • Herein, we present a unique case of nodular amyloidosis occurring in association with a cellular dermatofibroma.
  • [MeSH-major] Amyloid / metabolism. Histiocytoma, Benign Fibrous / pathology. Immunoglobulin Light Chains / metabolism. Skin Neoplasms / pathology

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  • (PMID = 20110798.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amyloid; 0 / Immunoglobulin Light Chains
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82. Pires I, Queiroga FL, Alves A, Silva F, Lopes C: Decrease of E-cadherin expression in canine cutaneous histiocytoma appears to be related to its spontaneous regression. Anticancer Res; 2009 Jul;29(7):2713-7
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  • [Title] Decrease of E-cadherin expression in canine cutaneous histiocytoma appears to be related to its spontaneous regression.
  • BACKGROUND: Canine cutaneous histiocytoma (CCH) is an epidermotropic tumour of Langerhans cells, most frequent in young dogs, which undergoes spontaneous regression.
  • CONCLUSION: This study strongly suggests a down-regulation of E-cadherin expression in CCH pathogenesis and progression.
  • The loss of E-cadherin expression might represent an activation/ maturation process of the tumoural cells constituting a switch for CCH regression.
  • [MeSH-major] Cadherins / metabolism. Histiocytoma, Benign Fibrous / veterinary. Neoplasm Regression, Spontaneous

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  • (PMID = 19596951.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Cadherins
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83. Papalas JA, Balmer NN, Wallace C, Sangüeza OP: Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review. Am J Dermatopathol; 2009 Jun;31(4):379-83
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  • [Title] Ossifying dermatofibroma with osteoclast-like giant cells: report of a case and literature review.
  • Dermatofibromas are fibrohistiocytic lesions with numerous histologic variants.
  • Ossifying dermatofibroma with osteoclast-like giant cells is an uncommon variant that has only rarely been reported.
  • We report another case of ossifying dermatofibroma with osteoclast-like giant cells and describe the immunohistochemical expression pattern of these rare lesions.
  • Large islands of spindled cells arranged in a storiform pattern were separated by broad fibrous bands.
  • A broad differential diagnosis, including variants of melanoma and osteosarcoma, should be considered when analyzing cutaneous lesions with a fibrohistiocytic component admixed with giant cells and metaplastic bone.
  • [MeSH-major] Giant Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Ossification, Heterotopic / pathology. Osteoclasts / pathology. Skin Neoplasms / pathology

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  • (PMID = 19461244.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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84. Meshikhes AW, Jan GM, Al-Jaroof AH: Fibrous histiocytoma of the breast. Saudi Med J; 2005 Feb;26(2):326-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous histiocytoma of the breast.
  • The histology after surgical excision revealed benign fibrous histiocytomas.
  • However, in patient 2 the benign fibrous histiocytoma recurred with low-grade malignancy after a year of the initial excision.
  • The second patient highlights the fact that malignant histiocytoma can occur in the pediatric age group and that the initial surgical treatment of benign fibrous histiocytoma should be aggressive to avoid recurrence and development of malignant changes.
  • We believe that our second patient is the youngest age ever reported in the literature with malignant fibrous histiocytoma.
  • [MeSH-major] Breast Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 15770318.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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85. Maier PC, Auw-Hädrich C, Reinhard T: [Recurrent fibrous histiocytoma at the corneoscleral limbus]. Klin Monbl Augenheilkd; 2008 Jan;225(1):99-100
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  • [Title] [Recurrent fibrous histiocytoma at the corneoscleral limbus].
  • [Transliterated title] Rezidivierendes fibröses Histiozytom am korneoskleralen Limbus.
  • This case report describes a rare fibrous histiocytoma at the corneoscleral limbus in a 10-year-old boy.
  • In our patient the tumour was histologically classified as benign, however, it presented with an invasive growth pattern and recurrency, so that a penetrating sclerokeratoplasty became necessary.
  • [MeSH-major] Corneal Diseases / surgery. Eye Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Keratoplasty, Penetrating. Limbus Corneae / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 18236380.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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86. Curcó N, Pagerols X, García M, Tarroch X, Vives P: Atrophic dermatofibroma accompanied by aneurysmatic characteristics. J Eur Acad Dermatol Venereol; 2006 Mar;20(3):331-3
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  • [Title] Atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • A 40-year-old man presented a painful haemorrhagic plaque on his chest in the same location where a nodular lesion had been presented for many years.
  • The lesion diagnosed as an anetoderma was excised and the biopsy showed an atrophic dermatofibroma accompanied by aneurysmatic characteristics.
  • [MeSH-major] Dermatofibrosarcoma / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 16503899.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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87. Matsumoto T, Ojima H, Akishima-Fukasawa Y, Hiraoka N, Onaya H, Shimada K, Mizuguchi Y, Sakurai S, Ishii T, Kosuge T, Kanai Y: Solitary hepatic lymphangioma: report of a case. Surg Today; 2010 Sep;40(9):883-9
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  • [Title] Solitary hepatic lymphangioma: report of a case.
  • Abdominal ultrasonography showed a 4-cm well-defined mass containing solid and cystic components in segment IV of the liver, and contrast-enhanced T1-weighted magnetic resonance imaging revealed heterogeneous enhancement within the tumor, indicating a solid or fibrous component.
  • A partial hepatectomy was performed, based on a preoperative diagnosis of sclerosing hemangioma and biliary cystadenoma or cystadenocarcinoma.

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  • (PMID = 20740355.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Homeodomain Proteins; 0 / LYVE1 protein, human; 0 / Tumor Suppressor Proteins; 0 / Vesicular Transport Proteins; 0 / monoclonal antibody D2-40; 0 / prospero-related homeobox 1 protein
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88. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Title] Malignant fibrous histiocytoma of the conjunctiva.
  • Fibrous histiocytomas are mesenchymal tumours composed of cells with fibroblastic to histiocytic differentiation.
  • To date, there are 18 cases of fibrous histiocytoma arising from the corneoscleral limbus reported in the literature.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • Herein, the clinicopathological features of a case of malignant fibrous histiocytoma are presented and its management with wide excision and cryotherapy followed by ocular reconstruction with amniotic membrane transplant is discussed.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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89. Pyatetsky D, Lissner GS, Bryar PJ, Lasky JB: Fibrous histiocytoma of the eyelid obliterating the punctum and the canaliculus. J Pediatr Ophthalmol Strabismus; 2007 Nov-Dec;44(6):379-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous histiocytoma of the eyelid obliterating the punctum and the canaliculus.
  • A 17-year-old boy with a growth in the medial right lower eyelid obliterating the lower punctum and canaliculus underwent incisional biopsy, which revealed fibrous histiocytoma.
  • [MeSH-major] Eyelid Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology

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  • (PMID = 18062498.001).
  • [ISSN] 0191-3913
  • [Journal-full-title] Journal of pediatric ophthalmology and strabismus
  • [ISO-abbreviation] J Pediatr Ophthalmol Strabismus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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90. Labonte S, Hanna W, Bandarchi-Chamkhaleh B: A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma. J Cutan Pathol; 2007 Nov;34(11):857-60
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  • [Title] A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma.
  • BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a relatively uncommon spindle cell tumor of the skin.
  • Cellular dermatofibroma (CDF) can mimic DFSP, but typical cases are easily differentiated from DFSP by their staining pattern for CD34 and factor 13a.
  • METHODS: Thirty-seven cases of clear-cut DFSP and 13 cases of clear-cut CDF were retrieved from the archives of Sunnybrook Health Sciences Center between 2000 and 2005.
  • [MeSH-major] Dermatofibrosarcoma / metabolism. Histiocytoma, Benign Fibrous / metabolism. Proto-Oncogene Proteins c-kit / biosynthesis. Skin Neoplasms / metabolism

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  • (PMID = 17944726.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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91. Shin JW, Park HS, Kim BK, Kim YA, Kim MG, Won CH, Cho S: Aneurysmal benign fibrous histiocytoma with atrophic features. Ann Dermatol; 2009 Feb;21(1):42-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aneurysmal benign fibrous histiocytoma with atrophic features.
  • Aneurysmal benign fibrous histiocytoma is an uncommon pathologic variant of dermatofibroma.
  • In addition to the features of a typical dermatofibroma, it has large cleft-like or cavernous blood-filled spaces with numerous hemosiderin pigments.
  • It should be differentiated from angiomatoid malignant fibrous histiocytoma, malignant melanoma, and vascular tumors such as Kaposi's sarcoma and angiosarcoma.
  • Atrophic dermatofibroma is also a rare variant of dermatofibroma, and the combination of aneurysmal and atrophic features is rarer still.
  • We report a case of aneurysmal benign fibrous histiocytoma with atrophic features in a 27-year-old male who had a grayish-brown atrophic patchy lesion on his back for 2 years.

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  • (PMID = 20548854.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2883367
  • [Keywords] NOTNLM ; Aneurysmal variant / Atrophy / Dermatofibroma
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92. Fernandez-Flores A, Manjon JA: Mitosis in dermatofibroma: a worrisome histopathologic sign that does not necessarily equal recurrence. J Cutan Pathol; 2008 Sep;35(9):839-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitosis in dermatofibroma: a worrisome histopathologic sign that does not necessarily equal recurrence.
  • BACKGROUND: High mitotic rate is a worrying histopathologic feature that pathologists occasionally face when diagnosing benign fibrous histiocytoma (BFH), that otherwise seem to be benign.
  • The clinical significance of this histologic feature has not been completely studied, because no studies on large series of BFH have been carried out, concerning mitotic rate as the only worrisome morphologic sign, in relation with recurrence.
  • CONCLUSIONS: We conclude that common BFH can occasionally present a high mitotic rate and still show a benign behavior.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Mitosis. Neoplasm Recurrence, Local. Skin Neoplasms / pathology

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  • (PMID = 18331566.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MIB-1 antibody
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93. Morris SR, deSousa JL, Barrett AW, Malhotra R: Benign fibrous histiocytoma of the eyelid mimicking keratoacanthoma. Ophthal Plast Reconstr Surg; 2007 Jan-Feb;23(1):73-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign fibrous histiocytoma of the eyelid mimicking keratoacanthoma.
  • We report a case of benign fibrous histiocytoma (BFH) of the medial canthus that mimicked keratoacanthoma in clinical appearance and growth.
  • Excisional biopsy confirmed the diagnosis of the cellular subtype of benign fibrous histiocytoma.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Keratoacanthoma / diagnosis

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  • (PMID = 17237703.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Hartel PH, Jackson J, Ducatman BS, Zhang P: CD99 immunoreactivity in atypical fibroxanthoma and pleomorphic malignant fibrous histiocytoma: a useful diagnostic marker. J Cutan Pathol; 2006 Sep;33 Suppl 2:24-8
Genetic Alliance. consumer health - Pleomorphic malignant fibrous histiocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD99 immunoreactivity in atypical fibroxanthoma and pleomorphic malignant fibrous histiocytoma: a useful diagnostic marker.
  • Atypical fibroxanthoma (AFX), a benign lesion, and pleomorphic malignant fibrous histiocytoma (MFH) are thought to represent points along the same neoplastic spectrum but with different prognoses and treatments.
  • [MeSH-major] Antigens, CD / biosynthesis. Biomarkers, Tumor / biosynthesis. Cell Adhesion Molecules / biosynthesis. Fibroma / metabolism. Fibroma / pathology. Gene Expression Regulation, Neoplastic. Histiocytoma, Malignant Fibrous / metabolism. Histiocytoma, Malignant Fibrous / pathology. Xanthomatosis / metabolism. Xanthomatosis / pathology

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  • (PMID = 16972949.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules
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95. Botrus G, Sciot R, Debiec-Rychter M: Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly. Cancer Genet Cytogenet; 2006 Jan 15;164(2):155-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly.
  • We report a case of a 39-year-old woman with a recurrent aneurysmal fibrous histiocytoma of the right lower leg.
  • Our case highlights the importance of distinguishing this recurrent but benign lesion from similarly appearing malignant skin tumors.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Histiocytoma, Benign Fibrous / genetics. Skin Neoplasms / genetics. Translocation, Genetic

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  • (PMID = 16434321.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ETS translocation variant 6 protein; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-ets; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / proto-oncogene protein bcl-3
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96. Senel FC, Bektas D, Caylan R, Onder E, Gunhan O: Malignant fibrous histiocytoma of the mandible. Dentomaxillofac Radiol; 2006 Mar;35(2):125-8
Genetic Alliance. consumer health - Malignant fibrous histiocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma of the mandible.
  • We report a case of malignant fibrous histiocytoma (MFH) primary within the mandible of a 32-year-old female.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Mandibular Neoplasms / diagnosis

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  • (PMID = 16549441.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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97. Gleason BC, Fletcher CD: Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol; 2008 Mar;32(3):354-62
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential.
  • Benign fibrous histiocytoma (FH) is one of the most common mesenchymal neoplasms of the skin.
  • Several histologic variants of cutaneous FH have been described, some of which also have distinct clinical features including a propensity for local recurrence.
  • Deep benign FH is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue.
  • Four cases were classified as atypical deep FH due to the presence of scattered markedly pleomorphic spindle cells within an otherwise histologically typical lesion.
  • In summary, deep FH has many histologic features in common with cutaneous cellular FH; however, it usually has a more diffusely storiform pattern than the latter, is well circumscribed, and may have striking hemangiopericytomalike vessels.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasm Metastasis / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 18300816.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin
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98. Ruiz Liso JM, Ruiz García J, Pardo López ML, Vaillo Vinagre A, Gutiérrez Martín A, Marrón Martínez MC, García Pérez MA: [Inflammatory malignant fibrous histiocytoma of the spermatic cord infiltrating an inguinal leiomyoma. Case report with conceptual and bibliographic reviews]. Arch Esp Urol; 2008 May;61(4):485-98
Genetic Alliance. consumer health - Malignant fibrous histiocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Inflammatory malignant fibrous histiocytoma of the spermatic cord infiltrating an inguinal leiomyoma. Case report with conceptual and bibliographic reviews].
  • [Transliterated title] Fibrohistiocitoma maligno "inflamatorio" de cordón espermático con infiltración sobre un leiomioma inguinal. Presentación de 1 caso con revisión conceptual y de la literatura.
  • OBJECTIVES: To study paratesticular malignant fibrous histiocytomas (FHM) from the clinical, histological, immunohistochemical and histogenetic, point of view.
  • METHODS: Through Medline and not index-linked search of international scientific literature we have found a total of 77 cases of paratesticular FHM that globally create diagnostic, terminological and therapeutic problems.
  • RESULTS: We include the case number 78 of FHM of spermatic cord, that presents a few special characteristics (not described before) of cutaneous fistula and infiltration of an inguinal leiomyoma, with histological and immunohistochemical confirmation.
  • We performed a conceptual review of this type of tumours, including the evaluation of contradictions and reclassifications that has undergone from its first description, which causes that they are underestimated and their real prevalence in international series is very variable: from 7 to 37% of paratesticular sarcomas.
  • Today, this term is synonymous of pleomorphic undifferentiated sarcoma and has been an exclusion diagnosis (Vimentin [+]/ CD 68 [+]--occasionally--without ultrastructural differences), reserving the inflammatory subtype for which they have an inflammatory and histiocytic component.
  • The accomplishment of an intraoperatory biopsy is essential in this location, since it is even difficult to know preoperatively, if a lesion is benign or malignant.
  • [MeSH-major] Genital Neoplasms, Male / pathology. Histiocytoma / pathology. Inguinal Canal. Leiomyoma / pathology. Neoplasms, Multiple Primary / pathology. Spermatic Cord

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  • (PMID = 18592766.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 84
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99. Torres Gómez FJ, Torres Olivera FJ: [Synchronous malignant fibrous histiocytomas in ileal and atrial locations]. Gastroenterol Hepatol; 2008 Jan;31(1):22-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Synchronous malignant fibrous histiocytomas in ileal and atrial locations].
  • [Transliterated title] Histiocitoma fibroso maligno de localización sincrónica ileal y auricular.
  • Diagnosis of malignant fibrous histiocytoma in ileal and atrial locations is uncommon and diagnosis of synchronous lesions in both locations is exceptional.
  • We present the case of a 60-year-old woman with a malignant fibrous histiocytoma in both locations.
  • Malignant fibrous histiocytoma is an aggressive neoplasm.
  • [MeSH-major] Heart Atria. Heart Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Ileal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 18218276.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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100. Canelas MM, Cardoso JC, Andrade PF, Reis JP, Tellechea O: Fibrous histiocytomas: histopathologic review of 95 cases. An Bras Dermatol; 2010 Mar-Apr;85(2):211-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous histiocytomas: histopathologic review of 95 cases.
  • Fibrous histiocytoma (FH) is a heterogeneous tumor composed of fibroblasts, histiocytes, and blood vessels.
  • We conducted a retrospective histopathologic analysis of 95 biopsies, performed over the last 3.5 years, of fibrous histiocytomas to analyze the location, delimitation, epithelial changes, induction of folliculo-sebaceous structures, cellularity, vascularity, collagen pattern, and types of composite cells of the FH.
  • In the majority of the biopsies, we confirmed the classical histopathologic features of fibrous histiocytomas.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 20520936.001).
  • [ISSN] 1806-4841
  • [Journal-full-title] Anais brasileiros de dermatologia
  • [ISO-abbreviation] An Bras Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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