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Items 1 to 37 of about 37
1. Bishop JA, Rekhtman N, Chun J, Wakely PE Jr, Ali SZ: Malignant solitary fibrous tumor: cytopathologic findings and differential diagnosis. Cancer Cytopathol; 2010 Apr 25;118(2):83-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant solitary fibrous tumor: cytopathologic findings and differential diagnosis.
  • Cytomorphologic features included mostly hypercellular smears with tissue fragments of monotonous, plump spindled cells with blunt-ended and indented nuclei and fragile, wispy cytoplasm.
  • CONCLUSIONS: The FNA diagnosis of malignant SFT is extremely difficult and needs histologic material for accurate interpretation.
  • Predominant FNA diagnoses were SFT or spindle cell neoplasm.
  • Malignant SFT must be included in the differential diagnosis of a spindle cell neoplasm of any anatomic site, particularly if it displays features not typical of benign SFT.
  • Immunoperoxidase staining has some utility, mainly in ruling out other neoplasms in the differential diagnosis.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasms, Connective Tissue / pathology

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  • [Copyright] (c) 2010 American Cancer Society.
  • (PMID = 20209623.001).
  • [ISSN] 1934-662X
  • [Journal-full-title] Cancer cytopathology
  • [ISO-abbreviation] Cancer Cytopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. Bermejo Casero E, Pérez Alonso D, Quevedo Losada S, López Rivero L: [Dermatofibroma metastasizing to the lung: current treatment]. Arch Bronconeumol; 2009 Oct;45(10):521-3
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  • They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm.
  • We discuss the histologic characteristics of this tumor that could raise suspicion of unusually aggressive behavior.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Dermis / pathology. Female. Humans. Neoplasm Recurrence, Local / surgery. Pneumonectomy. Positron-Emission Tomography. Shoulder. Thoracotomy

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  • (PMID = 19394746.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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3. Wu C, Wei Q, Utomo V, Nadesan P, Whetstone H, Kandel R, Wunder JS, Alman BA: Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. Cancer Res; 2007 Sep 1;67(17):8216-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Side population cells isolated from mesenchymal neoplasms have tumor initiating potential.
  • Although many cancers are maintained by tumor-initiating cells, this has not been shown for mesenchymal tumors, in part due to the lack of unique surface markers that identify mesenchymal progenitors.
  • We examined 29 mesenchymal tumors ranging from benign to high-grade sarcomas and identified SP cells in all but six samples.
  • There was a positive correlation between the percentage of SP cells and the grade of the tumor.
  • SP cells preferentially formed tumors when grafted into immunodeficient mice, and only cells from tumors that developed from the SP cells had the ability to initiate tumor formation upon serial transplantation.
  • Although SP cells are able to efflux rhodamine dye in addition to Hoechst 33342, we found that the ability to efflux rhodamine dye did not identify a population of cells enriched for tumor-initiating capacity.
  • Here, we identify a subpopulation of cells within a broad range of benign and malignant mesenchymal tumors with tumor-initiating capacity.
  • [MeSH-major] Neoplasms, Connective and Soft Tissue / pathology. Neoplastic Stem Cells / cytology
  • [MeSH-minor] Animals. Cell Proliferation. Disease Progression. Humans. Mice. Mice, Inbred NOD. Mice, SCID. Neoplasm Invasiveness. Neoplasm Transplantation / pathology. Transplantation, Heterologous

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  • (PMID = 17804735.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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4. Koljonen V, Jahkola T, Tukiainen E, Granroth G, Haglund C, Böhling T: Tenascin-C in primary Merkel cell carcinoma. J Clin Pathol; 2005 Mar;58(3):297-300
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  • BACKGROUND/AIMS: Merkel cell carcinoma (MCC) is a rare malignant cutaneous neuroendocrine tumour that mostly affects the elderly.
  • It shows rapid progression of the primary tumour, together with a vertical growth pattern into the underlying subcutaneous tissue.
  • Tenascin-C (Tn-C) is a large extracellular matrix glycoprotein that is expressed in various benign and malignant processes.
  • Staining was mainly seen in the invasion borders and within the connective tissue septae inside the tumours.
  • The expression of Tn-C correlated significantly with large tumour size.
  • CONCLUSIONS: Tn-C expression seems to increase with tumour size and malignant behaviour.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Merkel Cell / metabolism. Neoplasm Proteins / metabolism. Skin Neoplasms / metabolism. Tenascin / metabolism
  • [MeSH-minor] Aged. Aged, 80 and over. Cell Division. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasm Invasiveness. Prognosis

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  • (PMID = 15735164.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Tenascin
  • [Other-IDs] NLM/ PMC1770604
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5. Parfitt JR, Bella AJ, Izawa JI, Wehrli BM: Malignant neoplasm of perivascular epithelioid cells of the liver. Arch Pathol Lab Med; 2006 Aug;130(8):1219-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant neoplasm of perivascular epithelioid cells of the liver.
  • Although this group includes entities with distinct clinical features, such as angiomyolipoma, clear cell sugar tumor of the lung, and lymphangioleiomyomatosis, similar tumors have been documented in an increasing diversity of locations.
  • While most reported PEComas have behaved in a benign fashion, malignant PEComas have occasionally been documented.
  • We present a case of hepatic PEComa with benign histologic features, which nonetheless presented with metastases to multiple sites nearly 9 years later.
  • [MeSH-major] Epithelioid Cells / pathology. Liver / blood supply. Liver Neoplasms / pathology. Neoplasms, Connective Tissue / secondary

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  • (PMID = 16879028.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Siar CH, Nakano K, Ng KH, Tomida M, Nagatsuka H, Kawakami T: Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1. Eur J Med Res; 2010 Apr 8;15(4):180-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.
  • BACKGROUND: Squamous odontogenic tumor (SOT) is a rare benign odontogenic epithelial neoplasm.
  • Histo?pathological examination revealed a solid, locally-infiltrative neoplasm composed of bland-looking squamatoid islands scattered in a mature fibrous connective tissue stroma and the diagnosis was SOT.
  • [MeSH-major] Calcium-Binding Proteins / metabolism. Intercellular Signaling Peptides and Proteins / metabolism. Mandibular Neoplasms / genetics. Membrane Proteins / metabolism. Odontogenic Tumor, Squamous / genetics. Proto-Oncogene Proteins / metabolism. Receptor, Notch1 / metabolism. Receptors, Notch / metabolism
  • [MeSH-minor] Child. Connective Tissue / pathology. Female. Humans. Intracellular Signaling Peptides and Proteins

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  • (PMID = 20554499.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / NOTCH1 protein, human; 0 / NOTCH3 protein, human; 0 / NOTCH4 protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptor, Notch1; 0 / Receptors, Notch; 0 / delta protein; 134324-36-0 / Serrate proteins
  • [Other-IDs] NLM/ PMC3401003
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7. Kakutani K, Doita M, Nishida K, Akisue T, Maeno K, Zhang Z, Yurube T, Kurosaka M: Intractable sciatica due to intraneural nodular fasciitis detected by positron emission tomography. Spine (Phila Pa 1976); 2010 Oct 1;35(21):E1137-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These lesions are usually diagnosed by plain radiograph, myelography, computed tomography, and magnetic resonance imaging.Nodular fasciitis is a benign connective tissue tumor usually presenting as a firm, rapidly-growing lesion, occasionally arising in the forearm.
  • RESULTS: PET detected an abnormal lesion in the sciatic nerve in the posterior compartment of the patient's left thigh, indicating an intraneural tumor in the sciatic nerve.
  • Nodular fasciitis should be considered in the differential diagnosis of severe sciatica.
  • [MeSH-major] Fasciitis / complications. Fasciitis / diagnosis. Sciatica / diagnosis. Sciatica / etiology
  • [MeSH-minor] Accidental Falls. Adult. Diagnosis, Differential. Female. Humans. Neurosurgical Procedures / methods. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods. Treatment Outcome

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  • (PMID = 20622746.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Perna V, Rivas F, Morera R, Saumench J, Ramos R, Macia I, Ureña A, Escobar I, Villalonga R, Moya J: Localized (solitary) fibrous tumors of the pleura: an analysis of 15 patients. Int J Surg; 2008 Aug;6(4):298-301

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  • BACKGROUND: Localized fibrous tumors of the pleura (LFTPs) are rare neoplasms, which are considered to originate from submesothelial connective tissue.
  • Malignant transformation was seen in 1 patient 26 months after resection of a benign tumor.
  • One of these underwent redo-surgery and required pneumonectomy; in the other one surgery is not indicated because at the time of diagnosis the patient was 85 years.
  • CONCLUSIONS: For histologically benign tumors, because of the risk of recurrence and malignant transformation, complete surgical resection is indicated and long-term follow-up is recommended in all patients.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Pleura / pathology. Pleura / surgery. Prognosis. Radiography, Thoracic. Retrospective Studies. Risk Assessment. Survival Rate. Thoracotomy / methods. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18579460.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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9. Erdas E, Licheri S, Pinna G, Gerosa C, Ragazzo G: [Elastofibroma dorsi: case report and review of the literature]. G Chir; 2006 Oct;27(10):372-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Elastofibroma dorsi (ED) is a rare, benign, often bilateral lesion of the thoracic wall, occurring most commonly in the infra-scapular region beneath the muscular tissue, generally found in elderly women.
  • Whether ED should be considered as a true neoplasm or merely as a reaction of connective tissue to repetitive minor trauma is still debated.
  • ED has characteristic features but a low incidence and is therefore not always easily distinguished from other benign and malignant soft-tissue tumors.
  • Inappropriate treatment may thus be administrated in the absence of a definitive diagnosis.
  • Nonetheless, marginal surgical excision was performed and the tumor was histologically diagnosed as ED.
  • In conclusion, ED should be always considered in the differential diagnosis of tumors deeply located in the infra-scapular area, especially in elderly women.
  • As it is a benign lesion, surgical treatment is recommended only in symptomatic cases or if a large swelling is present.
  • [MeSH-major] Elastic Tissue / pathology. Fibroma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Scapula. Treatment Outcome

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  • (PMID = 17147850.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 28
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10. Joyner DE, Damron TA, Aboulafia A, Bokor W, Bastar JD, Randall RL: Heterogeneous expression of melanoma antigen (hMAGE) mRNA in mesenchymal neoplasia. Tissue Antigens; 2006 Jul;68(1):19-27
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  • [Title] Heterogeneous expression of melanoma antigen (hMAGE) mRNA in mesenchymal neoplasia.
  • In this study, hMAGEA2, hMAGEA3, hMAGEA4, and hMAGEC1 mRNA content in 21 benign mesenchymal tumors (representing seven histotypes) and 28 primary sarcomas (10 histotypes) was inventoried using real-time-PCR and then compared against hMAGE mRNA expression in non-sarcomatous malignancies, three cell lines, and muscle. hMAGEA2, hMAGEA3, and hMAGEC1 transcripts were infrequent in mesenchymal tissues in general, whereas hMAGEA4 mRNA was present in 84% of all mesenchymal tumors, 100% of non-sarcomatous tumors, all three cell lines, and in four of five muscle samples.
  • The presence of hMAGEA4 mRNA in muscle, plus the inconsistent and infrequent occurrence of hMAGEA2, hMAGEA3, and hMAGEC1 mRNA within and among mesenchymal tumor histotypes, makes these four hMAGE antigens unlikely candidates for sarcoma-specific immunotherapy.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Neoplasm Proteins / metabolism. Neoplasms / metabolism. Neoplasms, Connective Tissue / metabolism. Sarcoma / metabolism. Testis / immunology
  • [MeSH-minor] Cell Line. Cell Line, Tumor. Gene Expression. Humans. Male. Melanoma-Specific Antigens. Muscle, Skeletal / metabolism. Neoplasm Metastasis / pathology. RNA, Messenger / metabolism. RNA, Neoplasm / analysis

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  • [ErratumIn] Tissue Antigens. 2006 Aug;68(2):192
  • (PMID = 16774536.001).
  • [ISSN] 0001-2815
  • [Journal-full-title] Tissue antigens
  • [ISO-abbreviation] Tissue Antigens
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MAGEA1 protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm
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11. Cheng YS, Kessler H, Rees TD, Philofsky D, Pontikas A: Gingival swelling in a 13-year-old girl with multiple recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jan;103(1):85-91
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  • Histologic evaluation of the initial biopsy revealed groups of epithelioid cells surrounded by lymphocytes in the submucosal fibrous connective tissue, and it was diagnosed as noncaseating granulomatous inflammation.
  • With the tissue specimens from subsequent multiple excisions and several immunohistochemical studies, the diagnoses evolved to benign cellular infiltrate of undetermined origin, epithelioid hemangioma, proliferating endothelial cell neoplasm of uncertain biologic potential, atypical vascular tumor, epithelioid hemangioendothelioma, and kaposiform hemangioendothelioma.
  • We discuss the list of differential diagnoses from various pathologists and propose our diagnosis of epithelioid hemangioendothelioma based on its clinical behavior, histologic features, and immunohistochemical findings.
  • [MeSH-major] Alveolar Process / surgery. Gingiva / pathology. Gingival Neoplasms / pathology. Hemangioendothelioma, Epithelioid / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adolescent. Angiolymphoid Hyperplasia with Eosinophilia / pathology. Biomarkers / analysis. Biopsy. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Humans. Reoperation

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  • (PMID = 17178499.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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12. Mahajan S, Srikant N, Boaz K, George T: Osteoblastoma of maxilla with cartilaginous matrix: review of literature and report of a case. Singapore Dent J; 2007 Dec;29(1):12-8
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  • Osteoblastoma is a rare benign neoplasm of jaws.
  • [MeSH-minor] Adult. Connective Tissue / pathology. Diagnosis, Differential. Humans. Male. Maxillary Sinus / pathology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Osteoblasts / pathology

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  • (PMID = 18472525.001).
  • [ISSN] 0377-5291
  • [Journal-full-title] Singapore dental journal
  • [ISO-abbreviation] Singapore Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Singapore
  • [Number-of-references] 18
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13. Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW: Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am J Surg Pathol; 2005 Dec;29(12):1558-75
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  • [Title] Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
  • This family of tumors includes angiomyolipoma (AML), clear cell sugar tumor of the lung (CCST), lymphangioleiomyomatosis (LAM), and very rare tumors in other locations.
  • Because non-AML/non-LAM PEComas are extremely rare and their natural history and prognostic features undefined, we present our experience with 26 PEComas of soft tissue and the gynecologic tract, the largest series to date.
  • Recurrence and/or metastasis was strongly associated tumor size > median size (8 cm), mitotic activity greater than 1/50 HPF, and necrosis.
  • We conclude that PEComas of soft tissue and gynecologic origin may be classified as "benign," "of uncertain malignant potential," or "malignant."
  • Small PEComas without any worrisome histologic features are most likely benign.
  • [MeSH-major] Biomarkers, Tumor / analysis. Epithelioid Cells / pathology. Genital Neoplasms, Female / pathology. Neoplasms, Connective and Soft Tissue / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Follow-Up Studies. Humans. Immunohistochemistry. Immunophenotyping. Male. Middle Aged. Mitosis. Neoplasm Metastasis. Neoplasm Recurrence, Local. Retrospective Studies. Survival Analysis. Time Factors. Treatment Outcome. Tumor Burden

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  • (PMID = 16327428.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 56
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14. Marshall AE, Martin SE, Agaram NP, Chen JH, Horn EM, Douglas-Akinwande AC, Hattab EM: A 61-year-old woman with osteomalacia and a thoracic spine lesion. Brain Pathol; 2010 Mar;20(2):499-502
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  • Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia.
  • It is generally found in the soft tissue and bone of the extremities.
  • [MeSH-major] Osteomalacia / diagnosis. Osteomalacia / pathology. Spinal Neoplasms / diagnosis. Spinal Neoplasms / pathology. Thoracic Vertebrae
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neoplasms, Complex and Mixed / complications. Neoplasms, Complex and Mixed / diagnosis. Neoplasms, Complex and Mixed / pathology. Neoplasms, Connective Tissue / complications. Neoplasms, Connective Tissue / diagnosis. Neoplasms, Connective Tissue / pathology

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  • (PMID = 20438469.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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15. Mete O, Rotstein L, Asa SL: Controversies in thyroid pathology: thyroid capsule invasion and extrathyroidal extension. Ann Surg Oncol; 2010 Feb;17(2):386-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Controversies surrounding diagnostic criteria that distinguish benign from malignant thyroid follicular lesions have been brought to the attention of this community.
  • Moreover, the presence of adipose tissue within the thyroid gland and its pseudocapsule implies that thyroid tumor within fat tissue cannot be accepted as a criterion of ETE by that thyroid carcinoma.
  • [MeSH-major] Connective Tissue / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Thyroid Gland / anatomy & histology

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  • (PMID = 19949881.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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16. Basile JR, Klene C, Lin YL: Calcifying odontogenic cyst with odontogenic keratocyst: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Apr;109(4):e40-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The calcifying odontogenic cyst (COC), first identified as a separate and distinct lesion by Gorlin et al. in 1962, is an uncommon benign lesion, consisting of a proliferation of odontogenic epithelium and scattered nests of ghost cells and calcifications that may form the lining of a cyst or present as a solid mass.
  • The COC occurs alone or occasionally with odontomas or other odontogenic tumors, and it is this variable histology and clinical behavior that has raised the question of whether or not it is a cyst or a true neoplasm.
  • The odontogenic keratocyst (OKC) is a locally aggressive odontogenic cyst lined by parakeratinizing epithelium that also exhibits characteristics of a neoplasm, including rapid growth, a high rate of recurrence when treated conservatively, and the presence of a gene mutation.
  • [MeSH-minor] Adult. Ameloblasts / pathology. Biopsy. Connective Tissue / pathology. Diagnosis, Differential. Epithelium / pathology. Humans. Keratins. Male

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20303045.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 68238-35-7 / Keratins
  • [Number-of-references] 20
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17. Stavrinou P, Magras I, Stavrinou LC, Zaraboukas T, Polyzoidis KS, Selviaridis P: Primary extracerebral meningeal glioblastoma: clinical and pathological analysis. Cent Eur Neurosurg; 2010 Feb;71(1):46-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rarely, they are quite malignant and assume a bulky, well circumscribed appearance rendering the differential diagnosis from other CNS neoplasms difficult.
  • At surgery, the outer layer of the dura mater was intact and there was a clear brain-tumor interface without obvious pial disruption.
  • Histological examination showed a biphasic pattern consisting of benign connective tissue intermingled with bundles of what seemed to be a glioblastoma.
  • The tumor was identified as a primary meningeal glioblastoma.
  • This time, the pathological findings of the tumor were those of a typical glioblastoma multiforme.
  • We discuss the origin of the initial neoplasm and also the differential diagnosis that needs to include meningioma, aggressive glioblastoma infiltrating the dura and a recently recognized bimorphic CNS tumor: the desmoplastic glioblastoma.
  • [MeSH-minor] Dura Mater / pathology. Glial Fibrillary Acidic Protein / metabolism. Humans. Ki-67 Antigen / metabolism. Male. Middle Aged. Neoplasm Recurrence, Local

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  • [Copyright] Georg Thieme Verlag KG Stuttgart * New York.
  • (PMID = 20175027.001).
  • [ISSN] 1868-4912
  • [Journal-full-title] Central European neurosurgery
  • [ISO-abbreviation] Cent Eur Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen
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18. Egevad L, Carbin BE, Castellanos E, Hellstrom M, Valdman A: Atypical stromal hyperplasia of the prostate. Scand J Urol Nephrol; 2008;42(5):484-7
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  • This paper reports a case of atypical stromal hyperplasia (ASH) of the prostate, i.e. a proliferation of stromal cells with scattered atypical nuclei, growing between benign prostatic glands.
  • Although most ASHs arise in the transition zone in conjunction with benign prostatic hyperplasia, the current lesion was found in the peripheral zone of a 58-year-old man who underwent radical prostatectomy because of prostatic adenocarcinoma.
  • [MeSH-major] Connective Tissue / pathology. Neoplasm Recurrence, Local / pathology. Neoplasms, Multiple Primary / pathology. Prostatic Neoplasms / pathology. Stromal Cells / pathology

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  • (PMID = 18609271.001).
  • [ISSN] 0036-5599
  • [Journal-full-title] Scandinavian journal of urology and nephrology
  • [ISO-abbreviation] Scand. J. Urol. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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19. Saba L, Mallarini G: Osteoma of the mandible: case report and application of multi-detector-row CT rendering technique. Minerva Stomatol; 2008 May;57(5):275-8, 279-80

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  • Osteoma is an uncommon benign slow growing neoplasm of the bone, characterized by proliferation of osteoblasts forming bone trabeculas in a connective tissue stroma.

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  • (PMID = 18496489.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 27
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20. Erkan M, Reiser-Erkan C, Michalski CW, Kleeff J: Tumor microenvironment and progression of pancreatic cancer. Exp Oncol; 2010 Sep;32(3):128-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumor microenvironment and progression of pancreatic cancer.
  • Pancreatic ductal adenocarcinoma is characterized by « tumor desmoplasia », a remarkable increase in connective tissue that penetrates and envelopes the neoplasm.
  • It is becoming clear that this desmoplastic microenvironment of pancreatic cancer--which is forming approximately eighty percent of the tumor mass--is not a passive scaffold for the tumor cells but an active player in carcinogenesis.
  • Several chemotherapeutic agents and novel molecular targeted therapies against epithelial tumor cells--although showing antitumor activity in cell culture and mouse experiments--have failed to show significant effects in the clinic.
  • Thus, targeting pancreatic tumor cells alone seems unlikely to improve the dismal prognosis of pancreatic cancer.
  • Several primarily benign conditions associated with expansion of stromal and inflammatory components, such as chronic pancreatitis or hereditary pancreatitis are believed to increase the risk of pancreatic cancer.
  • [MeSH-major] Adenocarcinoma / metabolism. Pancreas / pathology. Pancreatic Neoplasms / metabolism. Tumor Microenvironment

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  • (PMID = 21403605.001).
  • [ISSN] 1812-9269
  • [Journal-full-title] Experimental oncology
  • [ISO-abbreviation] Exp. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ukraine
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21. Stacy GS, Dixon LB: Pitfalls in MR image interpretation prompting referrals to an orthopedic oncology clinic. Radiographics; 2007 May-Jun;27(3):805-26; discussion 827-8
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  • Patients referred to the authors' hospital for evaluation on suspicion of a bone or soft-tissue malignancy frequently present to the Orthopaedic Oncology Clinic with magnetic resonance (MR) images that show typical features of nonmalignant or nonneoplastic entities.
  • The purpose of this article is to review the benign entities that may be mistaken by the radiologist for a malignancy and thus lead to needless referral to an orthopedic oncologist.
  • Normal hematopoietic marrow and marrow edema due to a stress reaction may mimic a neoplasm at MR imaging, but knowledge of the typical patterns and locations of these features allows an accurate radiologic interpretation.
  • The MR imaging appearance of osteonecrosis, Paget disease, benign bone lesions, and rheumatologic conditions may be confusing; in such circumstances, radiographic findings may help formulate a correct diagnosis.
  • Knowledge of the common locations and appearances of bursae and ganglia is necessary so that radiologists do not misinterpret these benign entities as soft-tissue sarcomas.
  • Soft-tissue trauma and inflammation also may mimic tumors at MR imaging, but a familiarity with the imaging patterns of nonneoplastic change in muscle allows the avoidance of misinterpretation.
  • The clinical history, as always, is an important component of proper diagnosis.
  • The radiologist can be especially useful to both the clinician and the patient by recognizing entities that are highly unlikely to represent malignancy and by confidently reporting those entities as benign, thereby sparing the patient an unnecessary trip to the orthopedic oncologist.
  • [MeSH-major] Artifacts. Bone Diseases / diagnosis. Connective Tissue Diseases / diagnosis. Diagnostic Errors / prevention & control. Image Enhancement / methods. Referral and Consultation
  • [MeSH-minor] Adolescent. Adult. Bone Neoplasms / diagnosis. Female. Humans. Male. Middle Aged. Oncology Service, Hospital. Orthopedics. Pain Clinics. Soft Tissue Neoplasms / diagnosis

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  • [Copyright] (c) RSNA, 2007.
  • (PMID = 17495294.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
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22. Chmielik LP, Frackiewicz M, Krajewski R, Woloszczuk-Gebicka B, Chmielik M: Perioperative problems and treatment of a teenager with a juvenile angiofibroma refusing blood transfusion. Int J Pediatr Otorhinolaryngol; 2009 May;73(5):689-92
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  • OBJECTIVES: Juvenile angiofibroma is a benign, non-encapsulated neoplasm, consisting of vascular and connective tissue.
  • [MeSH-major] Angiofibroma / surgery. Blood Transfusion. Neoplasms, Connective Tissue / surgery. Nose Neoplasms / surgery. Postoperative Care. Preoperative Care. Treatment Refusal. Vascular Neoplasms / surgery

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  • (PMID = 19230984.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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23. Joyner DE, Wade ML, Szabo A, Bastar J, Coffin CM, Albritton KH, Bernard PS, Randall RL: Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo. J Cancer Res Clin Oncol; 2005 Mar;131(3):137-46
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  • [Title] Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo.
  • BACKGROUND: Mesenchymal neoplasia comprises a heterogeneous group of tumors with over 200 benign neoplasms and 100 sarcomas.
  • METHODS: cDNA microarray analyses were preformed on connective tissue tumors obtained at time of surgical resection or biopsy.
  • Messenger RNA (mRNA) from four general tumor classes was competitively hybridized against a human dermal fibroblast cell line comparator and the resulting gene expression profiles processed by ANOVA and linear discriminate analysis.
  • RESULTS: The tissue classification involved 18 patients with malignant peripheral nerve sheath tumors, giant cell containing tumors, benign spindle cell lesions, or Ewing's family of tumors.
  • Twenty-five differentially regulated genes considered most variable among the five tissue classes were identified.
  • CONCLUSIONS: Linear discriminate analysis of cDNA gene expression profiles partitioned mesenchymal tumor classes, even when constrained by limited sample sizes.
  • [MeSH-major] DNA Fingerprinting. DNA, Neoplasm / analysis. Mesenchymoma / diagnosis. Mesenchymoma / genetics. Neoplasms, Connective Tissue / diagnosis. Neoplasms, Connective Tissue / genetics. Oligonucleotide Array Sequence Analysis
  • [MeSH-minor] Analysis of Variance. Carcinoma / diagnosis. Carcinoma / genetics. Carcinoma, Giant Cell / diagnosis. Carcinoma, Giant Cell / genetics. Cell Line. Feasibility Studies. Fibroblasts. Gene Expression Regulation, Neoplastic. Humans. Linear Models. Nerve Sheath Neoplasms / diagnosis. Nerve Sheath Neoplasms / genetics. RNA, Messenger / analysis. RNA, Neoplasm / analysis. Sarcoma, Ewing / diagnosis. Sarcoma, Ewing / genetics. Skin / cytology

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  • (PMID = 15614524.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / RNA, Messenger; 0 / RNA, Neoplasm
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24. Shigeishi H, Yamaguchi S, Mizuta K, Nakakuki K, Fujimoto S, Amagasa T, Kamata N: Amphiregulin induces proliferative activities in osseous dysplasia. J Dent Res; 2009 Jun;88(6):563-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Human osseous dysplasia (OD) is a benign fibro-osseous neoplasm of periodontal ligament origin in which normal bone is replaced with fibrous connective tissue containing abnormal bone or cementum.

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  • (PMID = 19587163.001).
  • [ISSN] 1544-0591
  • [Journal-full-title] Journal of dental research
  • [ISO-abbreviation] J. Dent. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AREG protein, human; 0 / Amphiregulin; 0 / EGF Family of Proteins; 0 / Glycoproteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Recombinant Proteins
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25. Nakamura A, Iguchi H, Kusuki M, Yamane H, Matsuda M, Osako S: Laryngeal myxoma. Acta Otolaryngol; 2008 Jan;128(1):110-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myxoma is a rare benign tumor, and occurs most commonly in the mandible and maxilla in the head and neck region.
  • She had undergone laryngomicrosurgery for a vocal cord polyp 20 years previously, but did not know the histological diagnosis.
  • The pathologic diagnosis of the mass was myxoma.
  • Myxoma is a connective tissue tumor composed of multinucleate stellate cells suspended in an edematous, mucopolysaccharide-rich stroma.
  • Since myxomas may infiltrate surrounding tissue, they have a high incidence of local recurrence.
  • To prevent recurrence, myxoma should be surgically excised with surrounding normal tissue.
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Laryngoscopy. Microsurgery. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Polyps / diagnosis. Polyps / pathology. Polyps / surgery

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  • (PMID = 17851923.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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26. Angiero F, Crippa R, Stefani M: Granular cells tumour in the oral cavity: report of eleven cases treated with laser surgery. Minerva Stomatol; 2006 Jul-Aug;55(7-8):423-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cells tumour in the oral cavity: report of eleven cases treated with laser surgery.
  • METHODS: Between 1999 and 2004, 11 patients (6 females, 5 males; age range 28-66 years) were treated for tumours classified as being of neural origin; they were all myoblastomas or granular cells tumours (ex Abrikossoff tumour).
  • RESULTS: During follow-up, which ranged from 5 months to 5 years, there was no indication of tumour recurrence.
  • Histopathological analysis of haematoxylin and eosinstained sections showed all specimens to exhibit features typical of GCT; 6 tumours were well circumscribed, whereas 5 infiltrated adjacent connective tissue, muscle fibres and nerve bundles.
  • CONCLUSIONS: Granular cell tumour is a benign neoplasm with a tendency to relapse if not completely removed.
  • [MeSH-major] Granular Cell Tumor / surgery. Laser Therapy. Mouth Neoplasms / surgery

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  • (PMID = 17041542.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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27. Forsyth SF, Thompson KG, French AF, Halsey TR: Possible parachordoma in a dog. N Z Vet J; 2009 Oct;57(5):299-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CASE HISTORY: A 15-mm diameter mass developed in the S/C tissue overlying the right lateral gluteal muscle of a 6(1/2)-year-old female Flat-coated Retriever.
  • Histologically, the neoplasm consisted of similar large cells surrounded by thick fibrous connective tissue trabeculae.
  • DIAGNOSIS: The clinical, gross, histological and immunohistochemical findings are similar to those reported for parachordomas in humans.
  • CLINICAL RELEVANCE: This is the first reported case of a possible parachordoma in a dog, a benign tumour with cytological features of malignancy.
  • [MeSH-major] Dog Diseases / pathology. Neoplasms / veterinary. Soft Tissue Neoplasms / pathology

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  • (PMID = 19802045.001).
  • [ISSN] 0048-0169
  • [Journal-full-title] New Zealand veterinary journal
  • [ISO-abbreviation] N Z Vet J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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28. Lersundi A, Mankin HJ, Mourikis A, Hornicek FJ: Chondromyxoid fibroma: a rarely encountered and puzzling tumor. Clin Orthop Relat Res; 2005 Oct;439:171-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondromyxoid fibroma: a rarely encountered and puzzling tumor.
  • Chondromyxoid fibroma is an uncommon bone neoplasm, accounting in our series for less than 1% of all connective tissue tumors.
  • The tumor is more common in males, and located mostly in the metaphyseal areas of the lower extremity.
  • The tumor is benign and there have been no reports of metastases.
  • The method of treatment that has been used since the initial identification of the tumor has been curettage, which has a 20-25% recurrence rate.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Femur / pathology. Femur / radiography. Femur / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Pelvic Bones / pathology. Pelvic Bones / radiography. Pelvic Bones / surgery. Tibia / pathology. Tibia / radiography. Tibia / surgery. Transplantation, Homologous

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  • (PMID = 16205156.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Jones AC, Prihoda TJ, Kacher JE, Odingo NA, Freedman PD: Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Nov;102(5):639-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoblastoma is a benign neoplasm of bone characterized by a proliferation of osteoblasts forming bone trabeculae set in a vascularized fibrous connective tissue stroma.
  • We report 24 examples of this neoplasm arising in the maxilla and mandible and compare the clinical and radiographic characteristics of this neoplasm to 53 previously reported examples of osteoblastoma and osteoid osteoma in the jaws.
  • We also provide a rationale for use of the term "osteoblastoma" for any benign osteoblastic neoplasm arising in the jaws.

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  • (PMID = 17052641.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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30. Chang YS, Chu PH, Jung SM, Lim KE, Chu JJ, Hsueh C, Lee YS: Unusual cardiac papillary fibroelastoma in the right ventricular outflow tract. Cardiovasc Pathol; 2005 Mar-Apr;14(2):104-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac papillary fibroelastoma (CPF) is the second most common benign neoplasm of the heart.
  • This study describes the case of an 81-year-old man who was admitted to the hospital for severe vertigo and in whom a tumor at the right ventricular outflow tract (RVOT) was identified incidentally during echocardiography.
  • The unique chondroid metaplasia of fibrous tissue in this CPF has never been reported.
  • This work is the first to present an unusual CPF at the RVOT with reactive process of fibrous connective tissue.

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  • (PMID = 15780802.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers; 0 / von Willebrand Factor
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31. Takizawa I, Saito T, Kitamura Y, Arai K, Kawaguchi M, Takahashi K, Hara N: Primary solitary fibrous tumor (SFT) in the retroperitoneum. Urol Oncol; 2008 May-Jun;26(3):254-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary solitary fibrous tumor (SFT) in the retroperitoneum.
  • BACKGROUND: Solitary fibrous tumor (SFT) is an infrequent but distinct neoplasm, which generally arises from submesothelial connective tissue in the pleura.
  • The tumor size ranged between 2 and 26 (mean 9.1) cm.
  • The tumor cells were immunoreactive for vimentin in all cases, CD34 in 91% and Bcl-2 in 86%.
  • No significant difference was found between the recurrence rate of histologically benign and malignant cases.

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  • (PMID = 18452815.001).
  • [ISSN] 1078-1439
  • [Journal-full-title] Urologic oncology
  • [ISO-abbreviation] Urol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2
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32. Goh BK, Chow PK, Kesavan S, Yap WM, Wong WK: Outcome after surgical treatment of suspected gastrointestinal stromal tumors involving the duodenum: is limited resection appropriate? J Surg Oncol; 2008 Apr 1;97(5):388-91
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  • INTRODUCTION: Present surgical opinion is divided regarding the optimal method for the treatment of duodenal gastrointestinal stromal tumor (GIST) with some supporting the selective use of limited resection (LR) versus others who prefer pancreaticoduodenectomy (PD).
  • RESULTS: There were 15 GISTs, 1 leiomyosarcoma and 6 other non-GIST benign submucosal tumors.
  • Comparison between GIST and other benign tumors demonstrated that size was the only statistically significant distinguishing factor [8.5 (range, 2.5-18.0) vs. 2.5 (range, 1.5-8.0) cm, P = 0.014].
  • CONCLUSION: Benign non-GIST tumors may be distinguished from duodenal GIST as they are smaller in size.
  • [MeSH-minor] Adult. Aged. Cohort Studies. Female. Follow-Up Studies. Humans. Length of Stay. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasms, Connective and Soft Tissue / mortality. Neoplasms, Connective and Soft Tissue / pathology. Neoplasms, Connective and Soft Tissue / surgery. Paraganglioma / mortality. Paraganglioma / pathology. Paraganglioma / surgery. Retrospective Studies. Time Factors

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  • [Copyright] (Copyright) 2008 Wiley-Liss, Inc.
  • (PMID = 18163461.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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33. Ricke WA, Ishii K, Ricke EA, Simko J, Wang Y, Hayward SW, Cunha GR: Steroid hormones stimulate human prostate cancer progression and metastasis. Int J Cancer; 2006 May 1;118(9):2123-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tissue recombinants (TRs) composed of mouse urogenital mesenchyme (mUGM) plus an immortalized nontumorigenic human prostatic epithelial cell line (BPH-1) were grown under the kidney capsule of male athymic nude mice under different hormonal conditions.
  • In [T+E2]-implanted mice, mUGM+BPH-1 TRs formed carcinomas that contained a fibrous connective tissue stroma permeating the tumor; smooth muscle when present was associated with vasculature.
  • Epithelial cells isolated from untreated mUGM+BPH-1 TRs exhibited benign histology and formed small nontumorigenic grafts when subsequently transplanted into athymic nude mice.
  • [MeSH-minor] Animals. Cell Proliferation. Disease Models, Animal. Disease Progression. Epithelial Cells / physiology. Humans. Male. Mesoderm. Mice. Mice, Nude. Neoplasm Metastasis. Prostate / cytology. Transplantation, Heterologous

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  • Hazardous Substances Data Bank. ESTRADIOL .
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  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16331600.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Grant] United States / NIA NIH HHS / AG / AG0026604; United States / NCI NIH HHS / CA / CA84294; United States / NCI NIH HHS / CA / CA89520; United States / NCI NIH HHS / CA / CA96403; United States / NCI NIH HHS / CA / CA97725-01; United States / NICHD NIH HHS / HD / HD007263; United States / NCI NIH HHS / CN / N01CN15114-MAO; United States / NCI NIH HHS / CA / U01 CA96403
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 3XMK78S47O / Testosterone; 4TI98Z838E / Estradiol
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34. Arens C, Glanz H, Wönckhaus J, Hersemeyer K, Kraft M: Histologic assessment of epithelial thickness in early laryngeal cancer or precursor lesions and its impact on endoscopic imaging. Eur Arch Otorhinolaryngol; 2007 Jun;264(6):645-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Retrospective study including 161 patients undergoing surgery for a total of 206 benign and malignant lesions of the vocal folds.
  • Diagnosis was confirmed by histopathology in all cases.
  • The vocal fold mucosa revealed a progressive thickening from normal epithelium (NE = 147 microm) over the different grades of epithelial dysplasia (EDI = 258 microm, EDII = 301 microm, CIS = 445 microm) to early invasive carcinoma (EIC = 974 microm), while benign lesions presented only a slight epithelial thickening of an additional 100 microm.
  • Autofluorescence microscopy demonstrated a threefold higher fluorescence intensity of the submucosal connective tissue compared to the epithelium, which showed always the same weak intensity independent of the grade of dysplasia.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Fluorescence. Humans. Male. Microscopy, Fluorescence. Middle Aged. Neoplasm Invasiveness. Retrospective Studies

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  • (PMID = 17294207.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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35. Yoshioka K, Nagata R, Ueda M, Yamaguchi T, Konishi Y, Hosoi M, Inoue T, Yamanaka K, Iwai Y, Sato T: Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy. Intern Med; 2006;45(20):1157-60
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  • [Title] Phosphaturic mesenchymal tumor with symptoms related to osteomalacia that appeared one year after tumorectomy.
  • He had undergone surgery 2 years previously for a "benign unclassified mesenchymal tumor" in the skull, but there were no clinical symptoms related to osteomalacia.
  • The diagnosis of tumor-induced osteomalacia due to phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) was made by re-examining the pathologic specimens.
  • Clinicians and pathologists should be aware of the existence of PMTMCT especially nonphosphaturic or asymptomatic variants of this disorder.
  • [MeSH-minor] Fractures, Spontaneous / etiology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / complications. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Octreotide / administration & dosage. Octreotide / therapeutic use. Phosphates / therapeutic use. Radiosurgery. Vitamin D / analogs & derivatives. Vitamin D / therapeutic use

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  • (PMID = 17106161.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Phosphates; 1406-16-2 / Vitamin D; 66772-14-3 / 1,25-dihydroxyvitamin D; RWM8CCW8GP / Octreotide
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36. Wang Z, Guo Z, Li J, Li XD, Sang HX: Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection. Orthop Surg; 2010 Feb;2(1):19-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.
  • OBJECTIVE: To evaluate functional outcomes and complications of reconstruction of the proximal humerus after intra-articular tumor resection.
  • METHODS: Twenty-five patients who underwent Malawer I type resection and reconstruction of the proximal humerus for treatment of malignant or invasive benign tumors from August 1999 to August 2005 were evaluated.
  • A variety of reconstructive procedures, including modular tumor prosthesis, osteoarticular allograft, and allograft-prosthetic composite (APC), were performed after resection of tumor.
  • The modified Musculoskeletal Tumor Society (MSTS) evaluation system was used to assess limb functional outcome.
  • RESULTS: The study group consisted of 10 male and 15 female patients, among which there were 20 malignant and 5 benign tumors.
  • [MeSH-major] Arthroplasty, Replacement / methods. Bone Neoplasms / surgery. Humerus / surgery. Neoplasms, Connective Tissue / surgery. Shoulder Joint / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Lymphoma / mortality. Lymphoma / pathology. Lymphoma / surgery. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Postoperative Complications / epidemiology. Recovery of Function. Retrospective Studies. Treatment Outcome. Young Adult

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  • [Copyright] © 2010 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.
  • (PMID = 22009903.001).
  • [ISSN] 1757-7861
  • [Journal-full-title] Orthopaedic surgery
  • [ISO-abbreviation] Orthop Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Australia
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37. Theumann N, Hauser P, Schmidt S, Schnyder P, Leyvraz PF, Mouhsine E: [Osteoid osteoma and radiofrequency]. Rev Med Suisse; 2005 Dec 21;1(46):2989-94
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  • [Transliterated title] Thermoablation par radiofréquence de l'ostéome ostéoïde.
  • Osteoid osteoma and radiofrequency Osteoid osteoma relates to a benign skeletal neoplasm, smaller than 2 cm in diameter, composed of osteoid, highly vascularized connective tissue and surrounded by a ring of bone sclerosis.

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  • (PMID = 16429972.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Salicylates
  • [Number-of-references] 12
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