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Items 1 to 27 of about 27
1. Okay O, Dağlioğlu E, Yakicier C, Uren D, Dalgiç A, Ergüngör F: Choroid plexus papillomas in two siblings: case report. Turk Neurosurg; 2009 Jul;19(3):281-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroid plexus papillomas in two siblings: case report.
  • Choroid plexus papilloma (CPP) is a rare, benign epithelial brain tumor of the nervous system seen particularly in infants.
  • Some other form of malignant tumors was noted in the relatives of patients with CPPs, and some genetic defects regarding this coincidence were reported in the literature.
  • These neoplasms are occasionally bilateral and hydrocephalus is an associated sign in most of the cases.
  • All tumors were resected with parietotemporal craniotomy and a superior temporal sulcus approach to the lateral ventricle.
  • [MeSH-major] Papilloma, Choroid Plexus. Tumor Suppressor Protein p53 / genetics. Ventriculoperitoneal Shunt

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  • (PMID = 19621295.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
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2. Pratheesh R, Moorthy RK, Singh R, Rajshekhar V: Choroid plexus papilloma presenting as a non-contrast-enhancing fourth ventricular mass in a child. Neurol India; 2009 Jul-Aug;57(4):486-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroid plexus papilloma presenting as a non-contrast-enhancing fourth ventricular mass in a child.
  • Choroid plexus papilloma (CPP) is a rare benign tumor of the central nervous system with a propensity for location within the lateral ventricle in children.
  • Choroid plexus papillomas should be considered in the differential diagnosis of non-enhancing fourth ventricular masses.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Fourth Ventricle / pathology. Papilloma, Choroid Plexus / diagnosis

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  • (PMID = 19770555.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Wrede B, Liu P, Ater J, Wolff JE: Second surgery and the prognosis of choroid plexus carcinoma--results of a meta-analysis of individual cases. Anticancer Res; 2005 Nov-Dec;25(6C):4429-33
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  • [Title] Second surgery and the prognosis of choroid plexus carcinoma--results of a meta-analysis of individual cases.
  • Tumors of the choroid plexus (CPT) are rare.
  • While choroid plexus papillomas (CPP) are regarded as benign, choroid plexus carcinomas (CPC) have a dismal prognosis, and there is limited information available regarding the best treatment.
  • Three hundred and forty-seven patients had CPC, 15 atypical choroid plexus papillomas (APP) and 495 CPP.
  • This study suggests, if complete resection is not possible in the first surgery of a choroid plexus carcinoma, a second resection should be considered.
  • [MeSH-major] Choroid Plexus Neoplasms / surgery

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  • (PMID = 16334121.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] Greece
  • [Number-of-references] 22
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4. Akil H, Coupe NJ, Singh J: Spinal deposits of a benign choroid plexus papilloma. J Clin Neurosci; 2008 Jun;15(6):708-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal deposits of a benign choroid plexus papilloma.
  • Choroid plexus papillomas (CPP) are rare, benign tumors of the central nervous system.
  • Extensive seeding along the neural axis is usually associated with malignant transformation of the tumor.
  • [MeSH-major] Choroid Plexus Neoplasms / pathology. Papilloma, Choroid Plexus / pathology. Spinal Cord Neoplasms / secondary

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  • (PMID = 18406618.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 68238-35-7 / Keratins
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5. Ortega-Martínez M, Cabezudo-Artero JM, Fernández-Portales I, Pimentel JJ, Gómez de Tejada R: Diffuse leptomeningeal seeding from benign choroid plexus papilloma. Acta Neurochir (Wien); 2007 Dec;149(12):1229-36; discussion 1236-7
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  • [Title] Diffuse leptomeningeal seeding from benign choroid plexus papilloma.
  • Choroid plexus papillomas (CPP) are rare intracranial tumours with a favourable long-term outcome after surgical excision.
  • Although they are histologically benign, local recurrences may occasionally occur, but leptomeningeal dissemination is exceptional.
  • We report an unusual example of a fourth ventricle choroid plexus papilloma with diffuse leptomeningeal seeding.
  • Neither the initial tumour nor the recurrence showed malignant histological features.
  • We review the literature concerning leptomeningeal dissemination of benign choroid plexus papillomas.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Fourth Ventricle / surgery. Meningeal Neoplasms / secondary. Neoplasm Seeding. Papilloma, Choroid Plexus / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biopsy. Disease Progression. Fatal Outcome. Female. Humans. Ki-67 Antigen / analysis. Laminectomy. Magnetic Resonance Imaging. Meninges / pathology. Reoperation. S100 Proteins / analysis

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  • (PMID = 17924056.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / S100 Proteins
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6. Jovanović I, Ugrenović S, Vasović L, Petrović D, Cekić S: Psammoma bodies - friends or foes of the aging choroid plexus. Med Hypotheses; 2010 Jun;74(6):1017-20
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  • [Title] Psammoma bodies - friends or foes of the aging choroid plexus.
  • Psammoma bodies are structures classified in the group of dystrophic calcifications, which occur in some kind of tumors and in choroid plexus during the aging process.
  • Despite early discovery of their presence in choroid plexus stroma, mechanisms responsible for their formation remained unclear.
  • Their presence in some kind of tumors was even more extensively studied, but significant breakthrough in the field of their etiology was not attained, too.
  • However, till today correlation between their presence in tumors and aging is not established.
  • Also, there are not any data about structural differences between ones found in tumors and ones found in choroid plexus.
  • This might points to the assumption that besides the aging, some other causes might be involved in their formation in choroid plexus.
  • Furthermore, it is contradictory that forms, like psammoma bodies, present in such malignant formations as tumors, represent quite benign phenomenon in choroid plexus.
  • Firstly, psammoma bodies are present in stroma of tumors with predominantly papillomatous morphology, which is present in choroid plexus, too.
  • Initial forms of psammoma bodies might be formed in fibrovascular core of choroid plexus villi, similarly like in tumors papillae of papillary thyroid cancer.
  • Their further growth leads to the progressive destruction of both tumors papillae and choroidal villi.
  • Choroid plexus stroma is characterized by the fenestrated blood vessels presence, which are similar to newly formed vessels in tumors.
  • It can contain lymphocytes, macrophages, dendritic cells and myofibroblasts in cases with psammoma bodies, similarly to tumors stroma which is in activated, proinflammatory state.
  • So, all these facts can suggest that similar processes can lead to psammoma bodies formation in both tumors and choroid plexus and, that they might have harmful effect on choroid plexus structure and function during the aging process.
  • Further researches should be focused on detection of osteopontin and nanobacteria, already detected in tumors psammoma bodies, in choroid plexus ones.
  • Discovery of choroidal psammoma bodies mechanisms formation can be important for elucidation of some aspects in pathogenesis of some tumors, too.
  • Application of choroid plexus epithelial cells functional markers in cases with psammoma bodies should show their functional status.
  • [MeSH-major] Aging / pathology. Choroid Plexus / pathology. Inclusion Bodies / pathology
  • [MeSH-minor] Calcinosis / pathology. Choroid Plexus Neoplasms / pathology. Female. Humans. Male. Middle Aged. Models, Neurological. Stromal Cells / pathology

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  • (PMID = 20116930.001).
  • [ISSN] 1532-2777
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Miranda P, Lobato RD, Ricoy JR, Lagares A, Ramos A: Xanthogranuloma of the choroid plexus of the third ventricle: case report and literature review. Neurocirugia (Astur); 2005 Dec;16(6):518-22
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  • [Title] Xanthogranuloma of the choroid plexus of the third ventricle: case report and literature review.
  • Xanthogranulomas of the choroids plexus (XG) are benign tumours of debatable etiology which become rarely symptomatic.
  • [MeSH-major] Choroid Plexus / pathology. Choroid Plexus Neoplasms / diagnosis. Granuloma / diagnosis. Third Ventricle / anatomy & histology. Xanthomatosis / diagnosis

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  • (PMID = 16378134.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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8. Michalowski MB, de Fraipont F, Michelland S, Entz-Werle N, Grill J, Pasquier B, Favrot MC, Plantaz D: Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma. Cancer Genet Cytogenet; 2006 Apr 1;166(1):74-81
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  • [Title] Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma.
  • Ependymomas (EP) represent the third most frequent type of central nervous system (CNS) tumor of childhood, after astrocytomas and medulloblastomas.
  • No prognostic biological markers are available, and differentiation from choroid plexus papilloma (CPP) is difficult.
  • We detected a similar percentage of methylated tumors in both groups (71% in CPP and 77% in EP).
  • RASSF1A was the most frequently methylated gene in both benign tumors (66%) and EP (56%).
  • The genes associated with apoptosis were methylated in both groups of tumors.
  • The percentages of TRAIL pathway genes (CASP8, TFRSF10C, and TFRSF10D) methylated were 30, 9.5, and 36.4%, respectively, in ependymomas and 50, 50, and 16.7%, respectively, in choroid plexus papillomas.
  • No other gene was methylated in the benign tumors, whereas FHIT was methylated in 22%, RARB in 14.8%, BLU in 13.6%, p16INK4a in 11.1%, TNFRSF10C in 9.5%, and DAPK in 7.4% of ependymomas.
  • Although we did not observe a statistical relationship between methylation and clinical outcome, the methylation pattern does not appear to be randomly distributed in ependymoma and may represent a mechanism of tumor development and evolution.
  • [MeSH-major] Apoptosis Regulatory Proteins / genetics. Brain Neoplasms / genetics. DNA Methylation. Ependymoma / genetics. Membrane Glycoproteins / genetics. Papilloma, Choroid Plexus / genetics. Tumor Necrosis Factor-alpha / genetics. Tumor Suppressor Proteins / genetics


9. Jinhu Y, Jianping D, Jun M, Hui S, Yepeng F: Metastasis of a histologically benign choroid plexus papilloma: case report and review of the literature. J Neurooncol; 2007 May;83(1):47-52
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  • [Title] Metastasis of a histologically benign choroid plexus papilloma: case report and review of the literature.
  • Cerebrospinal metastases of benign choroid plexus papillomas (CPPs) are extremely rare.
  • Plain CT scan of the cranium revealed a partly calcified tumor filling the fourth ventricle and its right recess.
  • Cranial MRI showed an inhomogeneously contrast-enhancing tumor and leptomeningeal enhancement encasing the brain stem.
  • Complete resection of the tumor was carried out, and seedings to the floor of the fourth ventricle and cervico-medullary junction were found during the operation.
  • While intraoperative frozen section suggested pathology of papillary ependymoma or CPP, to our surprise, final histological examination revealed a benign choroid plexus papilloma.
  • This special case helps increase our understanding of benign CPPs and expands our differential diagnostic consideration of lesions with similar manifestations.
  • [MeSH-major] Central Nervous System Neoplasms / secondary. Cerebral Ventricle Neoplasms / secondary. Choroid Plexus Neoplasms / pathology. Choroid Plexus Neoplasms / secondary. Fourth Ventricle. Papilloma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Neoplasm Seeding. Neurosurgical Procedures / adverse effects. Subarachnoid Space. Tomography, X-Ray Computed

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  • (PMID = 17387433.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 33
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10. Aquilina K, Nanra JS, Allcutt DA, Farrell M: Choroid plexus adenoma: case report and review of the literature. Childs Nerv Syst; 2005 May;21(5):410-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choroid plexus adenoma: case report and review of the literature.
  • CASE REPORT: An 8-month-old infant with macrocephaly was found to have hydrocephalus and a cystic third ventricular tumour; biopsy of the tumour showed a choroid plexus adenoma.
  • The tumour was attached to the ependymal lining and was strongly adherent to the walls and floor of the anterior third ventricle.
  • In view of the benign nature of the tumour, no adjuvant radiotherapy or chemotherapy was given.
  • OUTCOME: There was no further tumour growth or clinical deterioration over a 6-year follow-up period.
  • [MeSH-major] Adenoma. Choroid Plexus Neoplasms

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  • (PMID = 15565450.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Prealbumin; 0 / S100 Proteins; 0 / Vimentin
  • [Number-of-references] 12
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11. Bollo RJ, Zagzag D, Samadani U: Synchronous choroid plexus papilloma of the fourth ventricle and ependymoma of the filum terminale: case report. Neurosurgery; 2010 Nov;67(5):E1454-9; discussion E1459
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  • [Title] Synchronous choroid plexus papilloma of the fourth ventricle and ependymoma of the filum terminale: case report.
  • BACKGROUND AND IMPORTANCE: We report the first case of synchronous choroid plexus papilloma of the fourth ventricle and myxopapillary ependymoma of the filum terminale.
  • Both are papillary World Health Organization grade I tumors known to disseminate via cerebrospinal fluid pathways.
  • After pathological diagnosis of a choroid plexus papilloma, the patient underwent resection of the spinal cord tumor.
  • CONCLUSION: This case underscores the need for separate pathological diagnosis in a patient with an intradural spine lesion in the context of a benign intracranial lesion.
  • We detail a panel of immunohistochemical markers essential for distinguishing the 2 papillary neuroectodermal tumors recovered in this case.
  • [MeSH-major] Cauda Equina / surgery. Choroid Plexus Neoplasms / surgery. Ependymoma / surgery. Neoplasms, Multiple Primary / surgery. Peripheral Nervous System Neoplasms / surgery

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  • (PMID = 20871433.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Banka S, Walsh R, Brundler MA: First report of occurrence of choroid plexus papilloma and medulloblastoma in the same patient. Childs Nerv Syst; 2007 May;23(5):587-9
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  • [Title] First report of occurrence of choroid plexus papilloma and medulloblastoma in the same patient.
  • INTRODUCTION: Choroid plexus papilloma is a benign epithelial brain tumour showing a striking predilection for infants and occurring most frequently in the lateral and fourth ventricles.
  • Medulloblastoma, on the other hand, is a primitive neuroectodermal tumour and is the most frequent malignant brain tumour of the posterior fossa in children.
  • In this study, we report a metachronous occurrence of choroid plexus papilloma and medulloblastoma in the same patient, which has not been reported before to the best of our knowledge.
  • CASE REPORT: The authors describe the case of a girl who presented with an atypical choroid plexus papilloma on the posterior wall of the left lateral ventricle at 3 months of age that was resected completely.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebral Ventricle Neoplasms / pathology. Medulloblastoma / pathology. Papilloma, Choroid Plexus / pathology

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  • (PMID = 17106748.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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13. Palmer C, Kalsi P, Scoones D, Bradey N, Strachan R: Recurrence of fourth ventricular choroid plexus papilloma with late occurrence of a spinal drop metastasis. Br J Neurosurg; 2010 Aug;24(4):482-4
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  • [Title] Recurrence of fourth ventricular choroid plexus papilloma with late occurrence of a spinal drop metastasis.
  • Choroid plexus papillomas are rare tumours, which occasionally spread both intracranially and down the spinal canal.
  • This is the first reported case of late recurrence, metastasis and transformation of a benign to an atypical lesion.
  • [MeSH-major] Fourth Ventricle / pathology. Papilloma, Choroid Plexus / secondary. Spinal Cord Neoplasms / secondary

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  • (PMID = 20632883.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Karim A, Fowler M, McLaren B, Cardenas R, Patwardhan R, Nanda A: Concomitant choroid plexus papillomas involving the third and fourth ventricles: A case report and review of the literature. Clin Neurol Neurosurg; 2006 Sep;108(6):586-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concomitant choroid plexus papillomas involving the third and fourth ventricles: A case report and review of the literature.
  • Choroid plexus papillomas (CPP) are histopathologically benign and rare central nervous system (CNS) neoplasms arising from the epithelium of the choroid plexus.
  • Pathology from the biopsy and both resections was benign CPP.
  • Concomitant CPPs may be secondary to mere coincidental tumor occurrence or to biologic seeding of cerebrospinal fluid (CSF) from a primary CPP despite otherwise benign histopathology.
  • [MeSH-major] Fourth Ventricle. Papilloma, Choroid Plexus / pathology. Third Ventricle

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  • (PMID = 15963638.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 21
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15. Yu H, Yao TL, Spooner J, Stumph JR, Hester R, Konrad PE: Delayed occurrence of multiple spinal drop metastases from a posterior fossa choroid plexus papilloma. Case report. J Neurosurg Spine; 2006 Jun;4(6):494-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Delayed occurrence of multiple spinal drop metastases from a posterior fossa choroid plexus papilloma. Case report.
  • Choroid plexus papilloma is a benign central nervous system tumor that occasionally spreads along the subarachnoid space.
  • The authors report the case of a 49-year-old man who presented with back pain 19 years after resection of a posterior fossa choroid plexus papilloma.
  • Magnetic resonance imaging revealed multiple spinal lesions without any residual or recurrent intracranial tumor.
  • All spinal lesions were resected and histologically diagnosed as atypical choroid plexus papilloma.
  • The authors suggest that patients in whom choroid plexus papilloma is diagnosed should undergo total neuraxis imaging at the time of initial diagnosis as well as periodic follow-up examinations after resection to rule out drop metastases.
  • [MeSH-major] Infratentorial Neoplasms / pathology. Papilloma, Choroid Plexus / secondary. Spinal Cord Neoplasms / secondary

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  • (PMID = 16776361.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Symss NP, Prasad AN, Vasudevan MC, Ramamurthi R: Exophytic choroid plexus papilloma of the fourth ventricle presenting with cerebrospinal fluid rhinorrhea: a case report. Surg Neurol; 2009 Jun;71(6):705-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Exophytic choroid plexus papilloma of the fourth ventricle presenting with cerebrospinal fluid rhinorrhea: a case report.
  • BACKGROUND: Choroid plexus papillomas are rare benign neoplasms that arise from the ventricular choroid plexus and are considered to be of ependymal origin.
  • CASE DESCRIPTION: We report a case of a 61-year-old male patient with a fourth ventricular exophytic choroid plexus papilloma extending caudally into the foramen magnum causing obstructive hydrocephalus.
  • Excision of the tumor takes precedence over any attempt to repair the fistula, as many a time, the CSF leak may stop.
  • [MeSH-major] Cerebrospinal Fluid Rhinorrhea / etiology. Papilloma, Choroid Plexus / pathology

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  • (PMID = 18313738.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. McCall T, Binning M, Blumenthal DT, Jensen RL: Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature. Surg Neurol; 2006 Jul;66(1):62-7; discussion 67-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature.
  • BACKGROUND: Choroid plexus papillomas are typically considered benign lesions, but histology is not always predictive of their behavior.
  • These tumors can metastasize anywhere along the neuraxis and may be intraventricular, subarachnoid, or intraparenchymal.
  • We present 2 cases that illustrate the wide diversity with which choroid plexus papillomas can disseminate.
  • CASE DESCRIPTIONS: The patient described in case 1 had a primary fourth ventricular choroid plexus papilloma that produced diffuse cystic subarachnoid and leptomeningeal lesions.
  • Patient 2 also had a primary fourth ventricular tumor but with subsequent suprasellar and spinal drop metastases.
  • CONCLUSIONS: Variations of choroid plexus papilloma dissemination include intraventricular, subarachnoid, and leptomeningeal nodules or cystic lesions, and intraparenchymal locations.
  • There is no consensus on the most effective treatment for choroid plexus papilloma metastases; surgical resection, chemotherapy, and radiation therapy may all yield benefits.
  • The prognosis for patients with disseminated choroid plexus papilloma can range from prolonged stable disease and symptoms to death within months.
  • [MeSH-major] Choroid Plexus / pathology. Choroid Plexus / surgery. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / therapy. Papilloma, Choroid Plexus / diagnosis. Papilloma, Choroid Plexus / therapy

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  • (PMID = 16793445.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 34
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18. Lauretti L, Fernandez E, Pallini R, Massimi L, Albanese A, Denaro L, Maira G: Long survival in an untreated solitary choroid plexus metastasis from renal cell carcinoma: case report and review of the literature. J Neurooncol; 2005 Jan;71(2):157-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long survival in an untreated solitary choroid plexus metastasis from renal cell carcinoma: case report and review of the literature.
  • Among them, the metastases localized only in the choroid plexus are exceptional and only six cases are reported in the literature.
  • Here we report on a patient with a single choroid plexus metastasis from RCC which presented an unusual biological behaviour.
  • For several years, such metastasis was interpreted as a benign intraventricular tumor and was not treated.
  • We think that this unusual biological behaviour of the tumor determined the late inset of the neurological symptoms, despite the location at the choroid plexus that usually leads to an early obstructive hydrocephalus.
  • To our knowledge, this 46 months survival is the longest survival of a patient affected by a single choroid plexus metastasis from RCC.
  • [MeSH-major] Carcinoma, Renal Cell / physiopathology. Carcinoma, Renal Cell / secondary. Choroid Plexus Neoplasms / physiopathology. Choroid Plexus Neoplasms / secondary. Kidney Neoplasms / pathology

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  • (PMID = 15690132.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 29
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19. Tiktinsky E, Horne T, Agranovich S, Landsberg S: Unilateral Tc-99m pertechnetate breast uptake: is it always benign? Clin Nucl Med; 2007 Sep;32(9):735-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unilateral Tc-99m pertechnetate breast uptake: is it always benign?
  • Although the thyroid gland is the principal organ with the ability to concentrate iodide and take up Tc-99m pertechnetate, other tissues such as choroid plexus, salivary glands, mucoid cells of stomach, and lactating breast tissue also possess this property.
  • [MeSH-minor] Adult. Breast Neoplasms / metabolism. Breast Neoplasms / radionuclide imaging. False Positive Reactions. Female. Humans. Radiopharmaceuticals / pharmacokinetics. Thyroid Neoplasms / metabolism. Thyroid Neoplasms / radionuclide imaging

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  • (PMID = 17710032.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; A0730CX801 / Sodium Pertechnetate Tc 99m
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20. Larouche V, Huang A, Bartels U, Bouffet E: Tumors of the central nervous system in the first year of life. Pediatr Blood Cancer; 2007 Dec;49(7 Suppl):1074-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumors of the central nervous system in the first year of life.
  • Among 1,289 infants identified from this literature review, the most common histological diagnoses are astrocytoma (30.5%), medulloblastoma (12.2%), ependymoma (11.1%), and choroid plexus tumors (11%).
  • Most tumors are supratentorial (65%).
  • The most important prognostic factors are histology (malignant vs. benign) and extent of resection.
  • Significant differences are noted for some tumor types by comparison with older children, for example in the aggressive behavior of low grade gliomas and the chemosensitivity of some high grade gliomas.
  • [MeSH-major] Brain Neoplasms / pathology

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  • [Copyright] Copyright 2007 Wiley-Liss, Inc.
  • (PMID = 17943961.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 71
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21. Warren FM, Shelton C, Wiggins RH 3rd, Herrod HC, Harnsberger HR: Imaging characteristics of metastatic lesions to the cerebellopontine angle. Otol Neurotol; 2008 Sep;29(6):835-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were several identifiable patterns of metastases to the CPA/IAC, including the flocculus (5), pia/arachnoid (12), dura (7), and choroid plexus (3).
  • Characteristics that differentiate metastatic lesions from benign lesions of the CPA include vasogenic edema on T2 and FLAIR imaging and multiple central nervous system lesions and lesions that are eccentric to the IAC.
  • [MeSH-major] Cerebellar Neoplasms / secondary. Cerebellopontine Angle. Ear, Inner
  • [MeSH-minor] Breast Neoplasms / epidemiology. Breast Neoplasms / pathology. Colonic Neoplasms / epidemiology. Colonic Neoplasms / pathology. Female. Humans. Kidney Neoplasms / epidemiology. Kidney Neoplasms / pathology. Lung Neoplasms / epidemiology. Lung Neoplasms / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology

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  • (PMID = 18636029.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Messing-Jünger AM, Riemenschneider MJ, Reifenberger G: A 21-year-old female with a third ventricular tumor. Brain Pathol; 2006 Jan;16(1):87-8, 93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A 21-year-old female with a third ventricular tumor.
  • Intraoperatively, the tumor showed a close relationship to the choroid plexus of the third ventricle.
  • Histopathology revealed a benign schwannoma of World Health Organization grade I.
  • To our knowledge, only 9 cases of intraventricular Schwann cell tumors have been published so far.
  • Most of these tumors were benign schwannomas, except for 2 cases of malignant peripheral nerve sheath tumors.
  • The tumor of our patient is the first reported schwannoma of the third ventricle.
  • The origin of intraventricular Schwann cell tumors is unknown.
  • They may arise from autonomic perivascular nerves in the choroid plexus or from ectopic neural crest-derived cells.
  • Histologically, intraventricular schwannoma needs to be distinguished from other spindle cell tumors, in particular pilocytic astrocytoma and fibroblastic meningioma.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Neurilemmoma / pathology. Neurilemmoma / surgery

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  • (PMID = 16612987.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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23. Kelley TW, Prayson RA, Barnett GH, Stevens GH, Cook JR, Hsi ED: Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue arising in the lateral ventricle. Leuk Lymphoma; 2005 Oct;46(10):1423-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The lesion developed as a mass within the lateral ventricle, appeared to be arising from the choroid plexus, and was not associated with meninges.
  • Histologically, there was a vaguely nodular, dense lymphoid infiltrate with occasional benign follicles colonized by marginal zone lymphoma, suggesting derivation from a focus of prior inflammation.
  • [MeSH-major] Brain Neoplasms / pathology. Lateral Ventricles / pathology. Lymphoma, B-Cell, Marginal Zone / pathology

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  • (PMID = 16194887.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Receptors, Complement 3d
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24. White SM, Graham JM Jr, Kerr B, Gripp K, Weksberg R, Cytrynbaum C, Reeder JL, Stewart FJ, Edwards M, Wilson M, Bankier A: The adult phenotype in Costello syndrome. Am J Med Genet A; 2005 Jul 15;136(2):128-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign tumors included multiple ductal papillomata in two women, and a fourth ventricle mass in one man, thought to be a choroid plexus papilloma.
  • [MeSH-minor] Adolescent. Adult. Arnold-Chiari Malformation / pathology. Developmental Disabilities / pathology. Female. Gastroesophageal Reflux / pathology. Growth Disorders / pathology. Heart Defects, Congenital / pathology. Humans. Male. Osteoporosis / pathology. Papilloma / pathology. Puberty, Delayed / pathology. Syndrome. Urinary Bladder Neoplasms / pathology

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • [ErratumIn] Am J Med Genet A. 2005 Nov 15;139(1):55
  • (PMID = 15940703.001).
  • [ISSN] 1552-4825
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM08243; United States / NICHD NIH HHS / HD / HD22657-11
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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25. Kasliwal MK, Suri A, Rishi A, Suri V, Sharma BS, Sarkar C: Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma. J Clin Neurosci; 2008 Dec;15(12):1401-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Xanthogranulomas are a group of benign lesions with an incidence of 1.6-7.0% in various autopsy series.
  • Although the lateral ventricle is the most frequent intracranial site involved, most symptomatic cases occur in the choroid plexus, involving the third ventricle.
  • The role of histopathology cannot be overemphasized in the diagnosis of this rare lesion and long-term follow-up is advised in cases managed conservatively owing to the propensity of this tumor to grow over time.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Granuloma / pathology. Xanthomatosis / pathology

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  • (PMID = 18952438.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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26. Borgwardt L, Højgaard L, Carstensen H, Laursen H, Nowak M, Thomsen C, Schmiegelow K: Increased fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) uptake in childhood CNS tumors is correlated with malignancy grade: a study with FDG positron emission tomography/magnetic resonance imaging coregistration and image fusion. J Clin Oncol; 2005 May 1;23(13):3030-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Increased fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) uptake in childhood CNS tumors is correlated with malignancy grade: a study with FDG positron emission tomography/magnetic resonance imaging coregistration and image fusion.
  • PURPOSE Positron emission tomography (PET) has been used in grading of CNS tumors in adults, whereas studies of children have been limited.
  • PATIENTS AND METHODS Nineteen boys and 19 girls (median age, 8 years) with primary CNS tumors were studied prospectively by fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) PET with (n = 16) or without (n = 22) H(2)(15)O-PET before therapy.
  • The FDG uptake in tumors was semiquantitatively calculated by a region-of-interest-based tumor hotspot/brain index.
  • Eight tumors without histologic confirmation were classified as WHO grade 1 based on location, MRI, and clinical course (22 to 42 months).
  • Results Four grade 4 tumors had a mean index of 4.27 +/- 0.5, four grade 3 tumors had a mean index of 2.47 +/- 1.07, 10 grade 2 tumors had a mean index of 1.34 +/- 0.73, and eight of 12 grade 1 tumors had a mean index of -0.31 +/- 0.59.
  • For these 34 tumors, FDG uptake was positively correlated with malignancy grading (n = 34; r = 0.72; P < .01), as for the 26 histologically classified tumors (n = 26; r = 0.89; P < .01).
  • The choroid plexus papilloma (n = 1) and the pilocytic astrocytomas (n = 3) had a mean index of 3.26 (n = 38; r = 0.57; P < .01).
  • Digitally performed PET/MRI coregistration increased information on tumor characterization in 90% of cases.
  • Improved PET/MRI imaging of the benign hypermetabolic tumors is needed to optimize clinical use.
  • [MeSH-major] Brain Neoplasms / pathology. Brain Neoplasms / radionuclide imaging. Fluorodeoxyglucose F18. Positron-Emission Tomography. Radiopharmaceuticals

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  • (PMID = 15860860.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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27. Woodward PJ, Sohaey R, Kennedy A, Koeller KK: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics; 2005 Jan-Feb;25(1):215-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation.
  • Fetal tumors are a diverse group of neoplasms, which are unique in their histologic characteristics, anatomic distribution, and pathophysiology.
  • The biologic behavior of tumors in the fetus may differ dramatically compared with that of the same tumor detected later in life.
  • Teratomas are the dominant histologic type and constitute the majority of both extracranial and intracranial neoplasms.
  • Large solid tumors may lead to cardiovascular compromise and hydrops fetalis.
  • Fetuses with intracranial tumors have a poor prognosis regardless of histologic type.
  • There are, however, two notable exceptions: lipomas and choroid plexus papillomas, both of which have a more favorable outcome.
  • Other fetal neoplasms include soft-tissue tumors (both benign and malignant), leukemia, mesenchymal hamartoma of the kidney, and liver tumors (hemangioendothelioma, mesenchymal hamartoma, and hepatoblastoma).
  • [MeSH-major] Fetal Diseases / diagnosis. Neoplasms / diagnosis
  • [MeSH-minor] Brain Neoplasms / diagnosis. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Teratoma / diagnosis. Ultrasonography, Prenatal

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  • (PMID = 15653597.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 82
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