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Items 1 to 100 of about 560
1. Larralde M, Boggio P, Abad ME, Pagotto B, Castillo A: [Subungual exostosis in a 14 years old boy]. Arch Argent Pediatr; 2009 Aug;107(4):349-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Subungual exostosis in a 14 years old boy].
  • [Transliterated title] Exostosis subungueal en un adolescente de 14 años.
  • Subungual exostosis is a benign bony outgrowth surrounded by a fibrocartilaginous capsule that mainly affects hallux terminal phalanx with subungual or periungular localization, and that clinically determines variable degree of nail plate or periungular soft tissues alterations, respectively, It is uncommon in childhood and more frequent in females.
  • Clinical suspicion is confirmed by the radiographic finding of a distinct trabecular bone growth arising from the dorsal aspect of the phalanx of the affected finger, on the lateral incidence.
  • We report a case of subungual exostosis located at the hallux in a 14-year-old boy suffering from subungual exostosis of the hallux that presented the characteristic triad of this entity: subungular tumor with nail plate deformity, digital pain and radiologic typical findings.
  • [MeSH-major] Exostoses

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  • (PMID = 19753444.001).
  • [ISSN] 1668-3501
  • [Journal-full-title] Archivos argentinos de pediatría
  • [ISO-abbreviation] Arch Argent Pediatr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Argentina
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2. Chooi YS, Siow YS, Chong CS: Cervical myelopathy caused by an exostosis of the posterior arch of C1. J Bone Joint Surg Br; 2005 Feb;87(2):257-9
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  • [Title] Cervical myelopathy caused by an exostosis of the posterior arch of C1.
  • We report a case of vertebral osteochondroma of C1 causing cord compression and myelopathy in a patient with hereditary multiple exostosis.
  • We highlight the importance of early diagnosis and the appropriate surgery in order to obtain a satisfactory outcome.
  • [MeSH-major] Cervical Vertebrae. Exostoses, Multiple Hereditary / complications. Osteochondroma / complications. Spinal Cord Diseases / etiology. Spinal Neoplasms / complications

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  • (PMID = 15736753.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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3. Carrera JE, Castillo PA, Molina OM: [Lumbar osteochondroma and radicular compression. A case report]. Acta Ortop Mex; 2007 Sep-Oct;21(5):261-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Lumbar osteochondroma and radicular compression. A case report].
  • [Transliterated title] Osteocondroma de lámina lumbar y compresión radicular. Reporte de un caso.
  • Most cartilage forming tumors are benign and rarely affect the spinal canal, their principal location is in humerus metaphysis, femur and tibia.
  • They represent 2% of all tumors and 2.6% of the benign tumors of the spine, usually located at the cervical spine.
  • It is speculated that the secondary ossification center may be aberrant cartilaginous tissue that causes the formation of osteochondroma.
  • From 1 to 4% of osteochondromas involve the spine and are commonly included in the posterior elements of the vertebrae and if located near neurological structures causing irritation and spinal compression is rare but potentially catastrophic.
  • The complete cure was to remove the exostosis of the lamina of right side of L4 with projection to the medullary canal and origin of the contact with the root of L4.
  • As the spinal osteochondromas are rare and tend to occur in young adults.
  • [MeSH-major] Lumbar Vertebrae / surgery. Nerve Compression Syndromes / etiology. Osteochondroma / complications. Spinal Cord Compression / etiology. Spinal Neoplasms / complications. Spinal Nerve Roots

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  • (PMID = 18159915.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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4. Mnif H, Zrig M, Koubaa M, Zammel N, Abid A: An unusual complication of pubic exostosis. Orthop Traumatol Surg Res; 2009 Apr;95(2):151-3
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  • [Title] An unusual complication of pubic exostosis.
  • We report the case of a left superior pubic ramus osteochondroma occurring in a 29-year-old man.
  • The patient consulted for a multiple exostoses disease revealed by a painful induration at the base of his penis.
  • CT-scan examination showed a pedunculated osteochondroma of the left superior pubic ramus compressing the urethra.
  • Surgical resection of the tumor confirmed the diagnosis of osteochondroma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Exostoses, Multiple Hereditary / complications. Osteochondroma / diagnosis. Pubic Bone / pathology. Urethral Stricture / etiology
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Follow-Up Studies. Humans. Immunohistochemistry. Male. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19321394.001).
  • [ISSN] 1877-0568
  • [Journal-full-title] Orthopaedics & traumatology, surgery & research : OTSR
  • [ISO-abbreviation] Orthop Traumatol Surg Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [General-notes] NLM/ Original DateCompleted: 20090724
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5. Lee SK, Jung MS, Lee YH, Gong HS, Kim JK, Baek GH: Two distinctive subungual pathologies: subungual exostosis and subungual osteochondroma. Foot Ankle Int; 2007 May;28(5):595-601
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two distinctive subungual pathologies: subungual exostosis and subungual osteochondroma.
  • BACKGROUND: The purpose of this study was to present features that differentiate subungual exostosis from subungual osteochondroma.
  • All were confirmed by radiographic and histologic evaluations to be subungual exostosis or subungual osteochondroma.
  • In the five patients with subungual exostosis, three (60%) had a toe lesion, and two (40%) had a finger lesion.
  • In the six patients with subungual osteochondroma, four (67%) had a toe lesion, and two (33%) had finger lesions.
  • CONCLUSIONS: Subungual exostosis and subungual osteochondroma are benign but have distinct osseous pathologies.
  • We concluded that subungual exostosis is clinically, developmentally, radiographically, and histologically distinct from subungual osteochondroma.
  • [MeSH-major] Bone Neoplasms / pathology. Exostoses / pathology. Nail Diseases / pathology. Osteochondroma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Male. Nails / pathology

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  • (PMID = 17559767.001).
  • [ISSN] 1071-1007
  • [Journal-full-title] Foot & ankle international
  • [ISO-abbreviation] Foot Ankle Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Stănescu L, Popescu CF, Niculescu CE, Dumitrescu D, Mogoantă SS, Georgescu I: Subungual exostosis of the big toe. Rom J Morphol Embryol; 2009;50(3):501-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subungual exostosis of the big toe.
  • The subungual exostosis is a benign bone tumor on the distal phalanx of a digit, beneath or adjacent to the nail, often bringing in discussion many differential diagnosis.
  • In the present, the radiological findings of the affected finger and the histopathological ones from the fragment excised confirmed the diagnosis of subungual exostosis.
  • The local excision of the entire region with the removal of the cartilaginous cap has been followed by a silent period without recurrences of almost two years when he as revised.
  • [MeSH-major] Exostoses / pathology. Hallux / pathology

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  • (PMID = 19690782.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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7. Trebicz-Geffen M, Robinson D, Evron Z, Glaser T, Fridkin M, Kollander Y, Vlodavsky I, Ilan N, Law KF, Cheah KS, Chan D, Werner H, Nevo Z: The molecular and cellular basis of exostosis formation in hereditary multiple exostoses. Int J Exp Pathol; 2008 Oct;89(5):321-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The molecular and cellular basis of exostosis formation in hereditary multiple exostoses.
  • The different clinical entities of osteochondromas, hereditary multiple exostoses (HME) and non-familial solitary exostosis, are known to express localized exostoses in their joint metaphyseal cartilage.
  • In the current study biopsies of osteochondromas patients were screened with respect to a number of cellular and molecular parameters.
  • Specifically, cartilaginous biopsy samples of nine HME patients, 10 solitary exostosis patients and 10 articular cartilages of control subjects were collected and cell cultures were established.
  • The EXT-1 mRNA and protein levels in chondrocyte cultures derived from all nine HME patients were elevated, compared with solitary exostosis patients or control subjects.
  • Furthermore, cell cultures of HME patients had significantly decreased pericellular heparan sulphate (HS) in comparison with cultures of solitary exostosis patients or control subjects.
  • Immunohistochemical staining of tissue sections and Western blotting of cell cultures derived from HME patients revealed higher levels of heparanase compared with solitary exostosis patients and of control subjects.
  • In conclusion, it appears that due to a mutated glycosyltransferase, the low content of pericellular HS in HME patients leads to the anatomical deformations with exostoses formation.
  • [MeSH-major] Chondrocytes / metabolism. Exostoses / genetics. Exostoses, Multiple Hereditary / genetics. N-Acetylglucosaminyltransferases / genetics

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  • (PMID = 18452536.001).
  • [ISSN] 1365-2613
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Glycosaminoglycans; 0 / RNA, Messenger; EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 3.2.1.- / heparanase; EC 3.2.1.31 / Glucuronidase
  • [Other-IDs] NLM/ PMC2613984
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8. Han IH, Kuh SU: Cervical osteochondroma presenting as brown-sequard syndrome in a child with hereditary multiple exostosis. J Korean Neurosurg Soc; 2009 May;45(5):309-11
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  • [Title] Cervical osteochondroma presenting as brown-sequard syndrome in a child with hereditary multiple exostosis.
  • Cervical cord compression due to osteochondroma in hereditary multiple exostosis (HME) is a rare condition, especially in young children.
  • In this report, we discuss a rare case of cervical osteochondroma presenting as Brown-Sequard syndrome (BSS) in a 7-year-old boy with HME.
  • MR image revealed cord compression by osteochondroma of the C7 lamina.
  • We removed the osteocondroma and the neurological deficit was improved.

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  • (PMID = 19516952.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2693794
  • [Keywords] NOTNLM ; Brown-Sequard syndrome / Hereditary multiple exostosis / Osteochondroma
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9. Hecht JT, Hayes E, Haynes R, Cole WG, Long RJ, Farach-Carson MC, Carson DD: Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes. Differentiation; 2005 Jun;73(5):212-21
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  • [Title] Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes.
  • An exostosis or osteochondroma is an aberrant bony growth occurring next to the growth plate either as an isolated growth abnormality or as part of the Hereditary Multiple Exostosis (HME) syndrome.
  • Mutations in either exostosin 1 (EXT1) or exostosin 2 (EXT2) gene cause the HME syndrome and also some isolated osteochondromas.
  • Previously, we demonstrated that HS is markedly diminished in the exostosis cartilage cap and that the HS proteoglycan, perlecan, has an abnormal distribution in these caps.
  • Systematic evaluation of exostosis cartilage caps and chondrocytes, both in vitro and in vivo, suggests that chondrocyte-specific cell functions account for diminished HS levels.
  • In addition, we provide evidence that perichondrial cells give rise to chondrocytes that clonally expand and develop into an exostosis.
  • [MeSH-major] Cell Differentiation / physiology. Chondrocytes / metabolism. Exostoses / metabolism. Heparitin Sulfate / metabolism

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  • (PMID = 16026543.001).
  • [ISSN] 0301-4681
  • [Journal-full-title] Differentiation; research in biological diversity
  • [ISO-abbreviation] Differentiation
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / R01 DE13542
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Collagen Type II; 9050-30-0 / Heparitin Sulfate; EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
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10. Toumi S, Ghnaya H, Essid A, Braham A, Jerbi S, Mrad-Daly K, Laouani-Kechrid C: [Hereditary multiple exostosis revealed by deep vein and arterial popliteal thrombosis]. Rev Med Interne; 2010 Apr;31(4):e7-10
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  • [Title] [Hereditary multiple exostosis revealed by deep vein and arterial popliteal thrombosis].
  • [Transliterated title] Maladie des exostoses multiples révélée par une thrombose poplitée veineuse et artérielle.
  • Radiologic assessment, guided by clinical findings, evidenced bilateral femoral and tibial exostosis resulting in a diagnosis of hereditary multiples exostosis.
  • Resection of the compressive osteochondroma and an arterial femorotibial bypass venous graft were performed in addition to prolonged anticoagulant therapy.
  • Hereditary multiple exostosis may be asymptomatic for long time.
  • Compression of adjacent vascular structures by an osteochondroma is a rare and potentially serious complication.

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  • [Copyright] Copyright 2009. Published by Elsevier SAS.
  • (PMID = 20219272.001).
  • [ISSN] 1768-3122
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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11. Unlu S, Demirkale I, Kalkan T, Tunc B, Bozkurt M: Large subungual exostosis of the great toe: a case report. J Am Podiatr Med Assoc; 2010 Jul-Aug;100(4):296-8
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  • [Title] Large subungual exostosis of the great toe: a case report.
  • A subungual exostosis is a benign lesion described as a variant of an osteochondroma.
  • It mostly affects the great toe, and it can be confused with an osteochondroma and a Nora's lesion.
  • The curative treatment for a subungual exostosis is complete excision, and the cartilaginous cap must be totally resected to prevent a possible recurrence.
  • [MeSH-major] Exostoses / surgery. Nail Diseases / surgery. Toes / surgery

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  • (PMID = 20660882.001).
  • [ISSN] 1930-8264
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Mansoor A, Beals RK: Multiple exostosis: a short study of abnormalities near the growth plate. J Pediatr Orthop B; 2007 Sep;16(5):363-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple exostosis: a short study of abnormalities near the growth plate.
  • The pathogenesis of multiple exostosis has been controversial with many theories put forward including the structural/mechanical theory, which emphasizes that the osteochondroma arises in the displaced growth plate cartilage penetrating a defective periosteum.
  • Recently, molecular genetics has offered the neoplastic model with tumor suppressor genes implicated in the development and pathogenesis of exostosis.
  • In this study, we demonstrated the spectrum of histological abnormalities in the developing exostosis present on the surface of the bone at the physis.
  • Seven skeletally immature patients with multiple exostoses were used in this study.
  • Coincident with removal of symptomatic exostoses that was adjacent to the physis, a thin strip of bone with overlying periosteum was removed to include the edge of the physis.
  • Our observations give support to the fact that precursor cells in the periosteum adjacent to the physis (also called the 'groove of Ranvier') gives rise to the chondrocytes that clonally expands and develops into exostosis.
  • [MeSH-major] Exostoses, Multiple Hereditary / pathology. Growth Plate / abnormalities

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  • (PMID = 17762677.001).
  • [ISSN] 1060-152X
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. LeClere LE, Riccio AI, Helmers SW, Thompson KE: Turret exostosis of the talus. Orthopedics; 2010 Jul;33(7):517

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Turret exostosis of the talus.
  • Turret exostosis is a benign osteocartilagenous lesion believed to arise from reactive perisoteum following relatively mild trauma.
  • This article presents an unusual case of a turret exostosis of the talar neck in a 12-year-old child.
  • Radiographs demonstrated a benign-appearing bony mass within the soft tissues anterior to the right ankle overlying the talar neck.
  • An excisional biopsy of the mass was performed and pathology was consistent with turret exostosis, demonstrating a central area of mature trabecular bone maturing via enchondral ossification with a thin hypocellular peripheral rim of cartilage.
  • The absence of a periosteal layer, abundant "blue bone," bizarre metaplastic cartilage, or marked cytologic atypia confirmed the diagnosis.
  • The current case represents the first account of a turret exostosis of the hindfoot, and the youngest patient with a histologically confirmed diagnosis.
  • [MeSH-major] Exostoses / pathology. Talus / pathology

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20608619.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Meissner SA, Vieth V, August C, Winkelmann W: Radiology-pathology conference: osteosarcoma in a cartilaginous exostosis of the femur. Clin Imaging; 2006 May-Jun;30(3):206-9
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  • [Title] Radiology-pathology conference: osteosarcoma in a cartilaginous exostosis of the femur.
  • Osteochondromas are common lesions in the metaphyseal segments of the long bones and are known to be able to degenerate into chondrosarcoma.
  • We present the case of a 20-year-old patient with an osteosarcoma at the base of a cartilaginous exostosis and discuss the causal relationship between the two lesions on the basis of the radiologic and pathologic findings.
  • [MeSH-major] Bone Neoplasms / diagnosis. Femur / radiography. Neoplasms, Second Primary / diagnosis. Osteochondroma / diagnosis. Osteosarcoma / diagnosis
  • [MeSH-minor] Adult. Biopsy / methods. Diagnosis, Differential. Humans. Knee / pathology. Knee / radiography. Magnetic Resonance Imaging / methods. Male. Pain / etiology

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  • (PMID = 16632158.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Conference; Journal Article
  • [Publication-country] United States
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15. Yoo WH, Kim JR, Jang KY, Lee SY, Park JH: Rapidly developed huge bursitis associated with scapular osteochondroma of the multiple exostosis: a case report. Rheumatol Int; 2009 Jan;29(3):317-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rapidly developed huge bursitis associated with scapular osteochondroma of the multiple exostosis: a case report.
  • Osteochondroma is the most common benign bone tumor and present as multiple masses in the hereditary disorder of multiple hereditary exostosis.
  • However, it rarely causes symptoms such as mass effects that produce several mechanical problems, and malignant transformation of the cartilaginous cap.
  • Large bursa formation with mechanical symptom has been very rarely reported in osteochondroma in which bursa is over the cap.
  • Here, we first described a patient with multiple hereditary exostosis who had developed huge bursitis on chest wall around the osteochondroma arising from the anterior surface of the right scapula after dumbbell lifting exercise for 3 months, and suggest that cystic mass can develop in any site of osteochondroma and should be early differentiated from malignant transformation of osteochondroma.
  • [MeSH-major] Bursitis / complications. Exostoses, Multiple Hereditary / complications. Resistance Training / adverse effects

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  • [Cites] Am J Clin Pathol. 1981 May;75(5):648-53 [7234751.001]
  • [Cites] Skeletal Radiol. 1991;20(7):513-6 [1754913.001]
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  • (PMID = 18682954.001).
  • [ISSN] 0172-8172
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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16. Martino A, Fabrizzi G, Costarelli L, Ilari M, de Benedictis FM: Haemothorax caused by isolated costal exostosis. Eur J Pediatr Surg; 2007 Apr;17(2):129-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Haemothorax caused by isolated costal exostosis.
  • We report an unusual case of spontaneous haemothorax in a 13-year-old girl with isolated costal exostosis.
  • Surgical excision of the exostosis was performed with complete resolution.
  • Costal exostosis should be considered in the differential diagnosis of spontaneous haemothorax in children in order to avoid unnecessary investigation and to establish an adequate treatment plan.
  • [MeSH-major] Exostoses / complications. Exostoses / surgery. Hemothorax / etiology. Ribs

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  • (PMID = 17503308.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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17. Franch J, Font J, Ramis A, Lafuente P, Fontecha P, Cairó J: Multiple cartilaginous exostosis in a Golden Retriever cross-bred puppy. Clinical, radiographic and backscattered scanning microscopy findings. Vet Comp Orthop Traumatol; 2005;18(3):189-93
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  • [Title] Multiple cartilaginous exostosis in a Golden Retriever cross-bred puppy. Clinical, radiographic and backscattered scanning microscopy findings.
  • Multiple cartilaginous exostosis was diagnosed in a six-month-old Golden Retriever cross-bred male with a history of forelimb lameness and isolated, but very painful, acute episodes.
  • Based on the history and radiographic findings, multiple cartilaginous exostosis was diagnosed.
  • Histology of the different exostoses demonstrated the presence of a hyaline cartilage cup surrounding a central area, formed mainly by bone and cartilage trabecullae.
  • At a greater depth, those cartilage trabecullae became osteochondral trabecullae, and the innermost were formed exclusively by woven and lamellar bone.
  • The histological and back-scattered electron scanning microscopy results conclude that it was a well-arranged normal endochondral ossification process that followed a centripetal pattern inside the bony mass, confirming the diagnoses of multiple cartilaginous exostoses.
  • [MeSH-major] Dog Diseases / diagnosis. Exostoses, Multiple Hereditary / veterinary
  • [MeSH-minor] Animals. Breeding. Diagnosis, Differential. Dogs. Forelimb. Lameness, Animal / diagnosis. Lameness, Animal / etiology. Male. Pain Measurement / veterinary

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  • (PMID = 16594452.001).
  • [ISSN] 0932-0814
  • [Journal-full-title] Veterinary and comparative orthopaedics and traumatology : V.C.O.T
  • [ISO-abbreviation] Vet Comp Orthop Traumatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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18. Pham-Duc ML, Reix P, Mure PY, Pracros JP, Moreux N, Bellon G: Hemothorax: an unusual complication of costal exostosis. J Pediatr Surg; 2005 Nov;40(11):e55-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemothorax: an unusual complication of costal exostosis.
  • We report a case of a spontaneous hemothorax in a 15-year-old girl because of costal exostosis.
  • This possibly may have been provoked by a nontraumatic rupture of markedly dilated pleural vessels because of long-standing friction between the exostosis and the pleura.
  • The authors conclude that exostosis of the rib is a rare cause of hemothorax in children and should be considered among possible etiologies in diagnosis.
  • [MeSH-major] Bone Neoplasms / complications. Hemothorax / etiology. Osteochondroma / complications

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  • (PMID = 16291144.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Takata K, Suzuki K, Kurosaki Y: Spontaneous hemothorax in hereditary multiple exostosis involving the ribs. Radiat Med; 2008 Jan;26(1):39-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous hemothorax in hereditary multiple exostosis involving the ribs.
  • Exostosis occurs in the ribs either sporadically or as a manifestation of a genetic disorder known as hereditary multiple exostoses.
  • Costal exostosis may cause chest pain and, on rare occasions, result in hemothorax.
  • We report a case of hemothorax owing to costal exostosis in a 4-year-old boy.
  • [MeSH-major] Exostoses, Multiple Hereditary / complications. Hemothorax / etiology. Ribs

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  • (PMID = 18236133.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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20. Giudicissi-Filho M, de Holanda CV, Borba LA, Rassi-Neto A, Ribeiro CA, de Oliveira JG: Cervical spinal cord compression due to an osteochondroma in hereditary multiple exostosis: case report and review of the literature. Surg Neurol; 2006;66 Suppl 3:S7-S11
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  • [Title] Cervical spinal cord compression due to an osteochondroma in hereditary multiple exostosis: case report and review of the literature.
  • BACKGROUND: Hereditary multiple exostosis is a benign disorder characterized by multiple osteochondromas affecting long and flat bones, although occasionally vertebral column involvement can be seen.
  • The objective of this manuscript is to describe a rare case of cervical myelopathy due to an exostosis arising from C7 in a patient with HME and a comprehensive review of the current literature.
  • CASE DESCRIPTION: We describe a case of HME in an 18-year-old girl with myelopathy characterized by quadriparesis due to an osteochondroma arising from the lamina of C7.
  • The patient underwent surgery, and a laminectomy was performed with a complete removal of the exostosis and spinal cord decompression.
  • CONCLUSIONS: Cervical spinal cord compression resulting from osteochondroma is an extremely serious complication of HME.
  • [MeSH-major] Cervical Vertebrae. Exostoses, Multiple Hereditary / complications. Osteochondroma / pathology. Spinal Cord Compression / etiology. Spinal Neoplasms / pathology

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  • (PMID = 17081854.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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21. Codron F, Vangrunderbeeck N, Florea O, Duvet S, Lamblin C: [Hereditary multiple exostosis complicated by spontaneous haemothorax]. Rev Mal Respir; 2008 Jan;25(1):87-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hereditary multiple exostosis complicated by spontaneous haemothorax].
  • [Transliterated title] Hémothorax spontané compliquant une maladie des exostoses multiples.
  • However some diseases, including hereditary multiple exostosis, have an increased incidence of this complication.
  • We report the case of a 22 year old patient with hereditary multiple exostosis who presented with a right sided haemothorax due to an exostosis of the seventh rib.
  • The pathophysiology of spontaneous haemothorax in the setting of hereditary multiple exostosis is discussed together with surgical treatment and long term follow up.
  • [MeSH-major] Exostoses, Multiple Hereditary / complications. Hemothorax / complications

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  • (PMID = 18288058.001).
  • [ISSN] 0761-8425
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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22. Kontogeorgakos VA, Lykissas MG, Mavrodontidis AN, Sioros V, Papachristou D, Batistatou AK, Beris AE: Turret exostosis of the hallux. J Foot Ankle Surg; 2007 Mar-Apr;46(2):130-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Turret exostosis of the hallux.
  • The histology report confirmed diagnosis of acquired osteochondroma.
  • [MeSH-major] Exostoses / surgery. Foot Injuries / complications. Toe Phalanges / surgery

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  • (PMID = 17331874.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Khine AA, Prabhakaran VC, Crompton J, Selva D: Lateral rectus restriction secondary to traumatic orbital exostosis. J AAPOS; 2009 Feb;13(1):109-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lateral rectus restriction secondary to traumatic orbital exostosis.
  • Bony exostoses can occur at the site of a fracture but are rare in facial bones.
  • We report a case of lateral rectus restriction secondary to a traumatic exostosis in the lateral orbital wall with resolution of diplopia after surgical removal of the lesion.
  • Although orbital masses may cause extraocular muscle restriction, to our knowledge, restriction secondary to an exostosis has not been previously reported.
  • A bony exostosis should therefore be included in the differential diagnosis of mechanical restriction of extraocular muscle movement, and surgical treatment is recommended in symptomatic patients.

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  • (PMID = 19117777.001).
  • [ISSN] 1528-3933
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Fung DA, Frey S, Markbreiter L: Bilateral symptomatic snapping biceps femoris tendon due to fibular exostosis. J Knee Surg; 2008 Jan;21(1):55-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral symptomatic snapping biceps femoris tendon due to fibular exostosis.
  • On flexion of the knee, the biceps tendon subluxed over a large exostosis, creating a snapping sound.
  • The case we present is the only one due to an exostosis, as well as the only one that required bilateral surgical repair.
  • [MeSH-major] Exostoses / complications. Fibula / radiography. Tendon Injuries / etiology

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  • (PMID = 18300673.001).
  • [ISSN] 1538-8506
  • [Journal-full-title] The journal of knee surgery
  • [ISO-abbreviation] J Knee Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. King JF, Kinney AC, Iacobellis SF 2nd, Alexander TH, Harris JP, Torre P 3rd, Doherty JK, Nguyen QT: Laterality of exostosis in surfers due to evaporative cooling effect. Otol Neurotol; 2010 Feb;31(2):345-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laterality of exostosis in surfers due to evaporative cooling effect.
  • OBJECTIVES: 1. To correlate exostosis severity with ear canal evaporative cooling.
  • RESULTS: Surfers from the west coast of the United States were twice as likely to have severe exostoses in the right ear compared with the left.
  • CONCLUSION: Exostosis severity seems to correspond to the ear that is more exposed to the predominant coastal wind.
  • We propose that evaporative cooling in a cold water environment contributes to greater progression of exostoses in the ear with more exposure to the predominant wind.
  • Exostosis removal using the postauricular approach carries a low complication rate.
  • [MeSH-major] Cold Temperature / adverse effects. Osteochondroma / etiology. Sports

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  • (PMID = 19806064.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Sankar B, Ng BY, Hopgood P, Banks AJ: Subungual exostosis following toe nail removal--case report. Int J Clin Pract Suppl; 2005 Apr;(147):132-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subungual exostosis following toe nail removal--case report.
  • We report the case of a young lady who developed a rapidly growing subungual exostosis on her right great toe following nail removal.
  • Inadvertent iatrogenic injury to the nail bed and underlying phalangeal periosteum during nail removal might have triggered off rapid bone growth resulting in the large exostosis.
  • To our knowledge, this aetiology for subungual exostosis formation has not been reported before.
  • [MeSH-major] Exostoses / etiology. Hallux / surgery. Nail Diseases / etiology. Nails / surgery. Postoperative Complications / etiology

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  • (PMID = 15875652.001).
  • [ISSN] 1368-504X
  • [Journal-full-title] International journal of clinical practice. Supplement
  • [ISO-abbreviation] Int J Clin Pract Suppl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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27. Carslake HB: Suture exostosis causing obstruction in the nasolacrimal duct in three horses. N Z Vet J; 2009 Aug;57(4):229-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Suture exostosis causing obstruction in the nasolacrimal duct in three horses.
  • CLINICAL FINDINGS: All horses had facial swellings and radiographic findings consistent with exostosis at the lacrimomaxillary suture, and ipsilateral epiphora.
  • DIAGNOSIS: Lacrimomaxillary suture exostosis.
  • CLINICAL RELEVANCE: Lacrimomaxillary suture exostosis should be considered as a differential diagnosis in cases of epiphora in horses.
  • Dacryocystorhinography, preferably retrograde and normograde, may be used as an aid to diagnosis.
  • [MeSH-major] Exostoses / radiography. Horse Diseases / radiography. Lacrimal Apparatus Diseases / veterinary. Nasal Obstruction / veterinary
  • [MeSH-minor] Animals. Diagnosis, Differential. Horses. Male. Nasolacrimal Duct / radiography. Treatment Outcome

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  • (PMID = 19649018.001).
  • [ISSN] 0048-0169
  • [Journal-full-title] New Zealand veterinary journal
  • [ISO-abbreviation] N Z Vet J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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28. Kanazawa M, Sumikura H, Tateda T: [Case of exostosis of the hard palate disturbing the insertion of Pro-Seal laryngeal mask]. Masui; 2008 Feb;57(2):171-3

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  • [Title] [Case of exostosis of the hard palate disturbing the insertion of Pro-Seal laryngeal mask].
  • We report a case of exostosis of the hard palate which had not bean ruled out in pre-operative examination and disturbed insertion of Pro-Seal laryngeal mask.
  • The hard palate has canopy construction, and it is difficult to find this exostosis by routine physical examination.
  • [MeSH-major] Exostoses. Laryngeal Masks. Palate, Hard

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  • (PMID = 18277564.001).
  • [ISSN] 0021-4892
  • [Journal-full-title] Masui. The Japanese journal of anesthesiology
  • [ISO-abbreviation] Masui
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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29. Raldi FV, Nascimento RD, Sá-Lima JR, Tsuda CA, Moraes MB: Excision of an atypical case of palatal bone exostosis: a case report. J Oral Sci; 2008 Jun;50(2):229-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Excision of an atypical case of palatal bone exostosis: a case report.
  • Bone exostosis has long been described in the literature, appearing in most cases as a torus palatinus or mandibularis.
  • Incidence is even higher when human skulls are examined post mortem, indicating that in some cases the exostosis is small and cannot be seen under the soft tissue.
  • Removal of an exostosis is usually associated with the construction of a prothesis, but in rare cases such as the present, the lesion enlarges enough to affect speech and feeding.
  • Few studies have reported the removal of such a large exostosis, and all were conducted in a hospital environment.
  • [MeSH-major] Exostoses / surgery. Maxillary Diseases / surgery. Palate, Hard / surgery

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  • (PMID = 18587217.001).
  • [ISSN] 1343-4934
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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30. Kurtzman GM, Silverstein LH, Shatz PC: A technique for surgical mandibular exostosis removal. Compend Contin Educ Dent; 2006 Oct;27(10):540-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A technique for surgical mandibular exostosis removal.
  • Exostosis, a slow-growing, benign bony outgrowth, is a common clinical finding and not usually a concern for patients.
  • This article describes a surgical technique for excision of exostosis through a case presentation.
  • The removal of the exostosis is illustrated through the use of a device that serves as an alternative to a scalpel, offering a safe, predictable outcome.
  • [MeSH-major] Exostoses / surgery. Mandibular Diseases / surgery. Oral Surgical Procedures / instrumentation

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  • (PMID = 17120387.001).
  • [ISSN] 1548-8578
  • [Journal-full-title] Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)
  • [ISO-abbreviation] Compend Contin Educ Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Abolghasemian M, Rezaie M, Behgoo A, Shoushtarizadeh T, Ghazavi MT: Exostosis-like intra-articular periosteal osteoblastoma: a rare case. Am J Orthop (Belle Mead NJ); 2010 Jun;39(6):E50-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Exostosis-like intra-articular periosteal osteoblastoma: a rare case.
  • Osteoblastoma is a relatively rare benign bone tumor, most often located in the vertebral column or metaphysis of the long bones, particularly the femur and the tibia.
  • Exostosis-like appearance is not common even in periosteal osteoblastoma, a very rare type of this tumor.
  • Here we report the case of a 25-year-old man with intra-articular exostosis-like periosteal osteoblastoma of the hip that resulted in impingement and osteoarthritis.
  • [MeSH-major] Bone Neoplasms / pathology. Hip Joint / pathology. Osteoblastoma / pathology. Periosteum / pathology

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  • (PMID = 20631934.001).
  • [ISSN] 1934-3418
  • [Journal-full-title] American journal of orthopedics (Belle Mead, N.J.)
  • [ISO-abbreviation] Am J. Orthop.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Lee SJ, Pho RW: Report of an unusual case of trigger finger secondary to phalangeal exostosis. Hand Surg; 2005 Jul;10(1):135-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Report of an unusual case of trigger finger secondary to phalangeal exostosis.
  • We describe a patient who had triggering of the left middle finger at the proximal interphalangeal joint due to an exostosis blocking the flexor tendons gliding.
  • Removal of the exostosis relieved the problem.
  • [MeSH-major] Exostoses / complications. Finger Joint / physiopathology. Tenosynovitis / etiology

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  • (PMID = 16106517.001).
  • [ISSN] 0218-8104
  • [Journal-full-title] Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand
  • [ISO-abbreviation] Hand Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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33. Parker RG: Dorsal foot pain due to compression of the deep peroneal nerve by exostosis of the metatarsocuneiform joint. J Am Podiatr Med Assoc; 2005 Sep-Oct;95(5):455-8
MedlinePlus Health Information. consumer health - Pain.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dorsal foot pain due to compression of the deep peroneal nerve by exostosis of the metatarsocuneiform joint.
  • Podiatric physicians often encounter patients with dorsal foot pain related to either an exostosis or a ganglion arising at the junction of the first metatarsal and the cuneiform.
  • Removal of the exostosis or ganglion is routine but may not relieve the pain.
  • Exostosis surgery can result in worsening of pain owing to injury of the deep peroneal nerve.
  • In this retrospective series, ten patients with dorsal foot pain-related exostosis or ganglion underwent measurement of the cutaneous pressure threshold of the skin of the dorsal first web space to determine whether compression of the deep peroneal nerve was related to their symptoms.
  • During surgery, each patient was noted to have a site of compression of the deep peroneal nerve by the extensor hallucis brevis tendon at the metatarsocuneiform exostosis.
  • Neurosensory testing can identify pain related to the deep peroneal nerve in patients with a dorsal exostosis or ganglion in this region.
  • [MeSH-major] Exostoses / complications. Foot / physiopathology. Pain / etiology. Peroneal Nerve / physiopathology

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  • (PMID = 16166463.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Mannoji C, Yamazaki M, Kamegaya M, Saisu T, Minami S, Takahashi K: Paraparesis caused by rib exostosis in a child with Down syndrome: a case report. Spine (Phila Pa 1976); 2008 Nov 1;33(23):E911-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paraparesis caused by rib exostosis in a child with Down syndrome: a case report.
  • OBJECTIVE: We describe a case of paraparesis caused by a rib exostosis compressing the spinal cord.
  • SUMMARY OF BACKGROUND DATA: Exostoses are the most common benign tumors of bone and often arise from the metaphyses of long bones.
  • Spinal exostoses are uncommon lesions, but when present, may compress the spinal cord and cause significant neurologic symptoms.
  • Spinal exostoses leading to neurologic impairment typically arise from vertebrae or laminae.
  • It is very rare for exostoses originating from rib heads to cause neurologic symptoms.
  • RESULTS: A 10-year-old boy with multiple exostoses and Down syndrome was referred to our hospital because of difficulty walking.
  • Radiographs, computed tomography scan, and magnetic resonance imaging revealed that an exostosis arising from the left eighth rib head was compressing the spinal cord.
  • The exostosis was resected and the patient's neurologic symptoms resolved.
  • CONCLUSION: Exostosis rising from the rib head can compress the spinal cord and cause neurologic deficits.
  • Surgical resection of the rib exostosis should be strongly considered when neurologic symptoms develop.
  • [MeSH-major] Bone Neoplasms / complications. Down Syndrome / complications. Exostoses / complications. Osteochondroma / complications. Paraparesis / etiology


35. Arnoldner C, Stöver T, Bartling SH, Windhagen A, Durisin M, Averbeck T, Lenarz T: [Exostosis of the internal auditory canal in a patient with myotonic dystrophy]. Laryngorhinootologie; 2006 Oct;85(10):755-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Exostosis of the internal auditory canal in a patient with myotonic dystrophy].
  • Routinely performed computed tomography of the temporal bones revealed the rare picture of exostosis of the internal auditory canals and the medial surface of the petrous bones.
  • To our knowledge, this is the first report describing exostosis of the internal auditory canal in a patient with myotonic dystrophy, although at present it remains unclear in how far there is a causal connection between these two pathologies.
  • [MeSH-major] Ear Canal. Exostoses. Hearing Loss, Sensorineural / etiology. Myotonic Dystrophy / complications. Petrous Bone
  • [MeSH-minor] Audiometry, Pure-Tone. Humans. Male. Middle Aged. Temporal Bone / radiography. Tomography, X-Ray Computed

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  • (PMID = 17031763.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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36. Darilek S, Wicklund C, Novy D, Scott A, Gambello M, Johnston D, Hecht J: Hereditary multiple exostosis and pain. J Pediatr Orthop; 2005 May-Jun;25(3):369-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hereditary multiple exostosis and pain.
  • This study was undertaken to characterize pain in individuals with hereditary multiple exostosis (HME).
  • [MeSH-major] Exostoses, Multiple Hereditary / complications. Pain / etiology. Sickness Impact Profile

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  • (PMID = 15832158.001).
  • [ISSN] 0271-6798
  • [Journal-full-title] Journal of pediatric orthopedics
  • [ISO-abbreviation] J Pediatr Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Hadj Henni A, Job L, Lefebvre F, Marcus C, Long A: [Popliteal venous thrombosis associated with a false aneurysm revealing femoral exostosis in a child]. J Mal Vasc; 2010 Dec;35(6):359-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Popliteal venous thrombosis associated with a false aneurysm revealing femoral exostosis in a child].
  • [Transliterated title] Thrombose veineuse profonde et faux anévrisme poplité révélant une exostose fémorale chez une enfant.
  • Knee X-rays showed a distal femoral exostosis.
  • MRI clarified the relationship between the false aneurysm and the exostosis.
  • Bone scintigraphy eliminated multiple exostoses.
  • Vascular complications of exostoses are infrequent and the association with deep venous thrombosis and false aneurysm is exceptional.
  • [MeSH-major] Aneurysm, False / etiology. Exostoses / complications. Femur. Popliteal Vein. Venous Thrombosis / etiology

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20832211.001).
  • [ISSN] 0398-0499
  • [Journal-full-title] Journal des maladies vasculaires
  • [ISO-abbreviation] J Mal Vasc
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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38. Parratte S, Launay F, Jouve JL, Malikov S, Petit P, Bollini G: [A pediatric case of rupture of the brachial artery and radial nerve palsy secondary to proximal humeral exostosis]. Rev Chir Orthop Reparatrice Appar Mot; 2007 Apr;93(2):186-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A pediatric case of rupture of the brachial artery and radial nerve palsy secondary to proximal humeral exostosis].
  • [Transliterated title] Rupture de l'artère brachiale et paralysie radiale secondaire à une exostose proximale de l'humérus chez une enfant de 14 ans.
  • Rupture of the brachial artery associated with radial nerve palsy in a context of exostosis of the proximal humerus has not been described to date in the literature.
  • The diagnosis was not confirmed by computed tomography with contrast injection but was confirmed by magnetic resonance imaging which eliminated malignant transformation of the exostosis.
  • After checking the neurovascular bundles and evacuating the hematoma, treatment consisted in resection of the exostosis and arterial repair with an autologous venous graft.
  • We discuss the diagnostic and therapeutic challenges which present vascular complications due to exostosis.
  • [MeSH-major] Brachial Artery / pathology. Exostoses / complications. Humerus / pathology. Joint Diseases / complications. Paralysis / etiology. Radial Neuropathy / etiology. Shoulder Joint / pathology

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  • (PMID = 17401293.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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39. Villas C, Del Río J, Valenti A, Alfonso M: Symptomatic medial exostosis of the great toe distal phalanx: a complication due to over-correction following akin osteotomy for hallux valgus repair. J Foot Ankle Surg; 2009 Jan-Feb;48(1):47-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic medial exostosis of the great toe distal phalanx: a complication due to over-correction following akin osteotomy for hallux valgus repair.
  • Preoperative radiographic evaluation of the patient's foot revealed the first ray to be longer than the second, a 12 degrees first intermetatarsal angle, a 33 degrees hallux abductus angle, and an exostosis at the medial aspect of the base of the hallux that was not considered by the surgeon to be important.
  • The pain correlated both clinically and radiologically with the exostosis at the base of the distal phalanx, and had become symptomatic only after the hallux had been operatively realigned.
  • At 6 months postoperative, percutaneous exostectomy was undertaken to remove the exostosis.
  • The clinical importance of a medial exostosis localized to the base of the distal phalanx of the hallux must be taken into consideration whenever hallux valgus correction is undertaken, and this is particularly important whenever an Akin osteotomy is being considered.
  • [MeSH-major] Exostoses / etiology. Hallux Valgus / surgery. Osteotomy / adverse effects

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  • (PMID = 19110159.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Storlazzi CT, Wozniak A, Panagopoulos I, Sciot R, Mandahl N, Mertens F, Debiec-Rychter M: Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22). Int J Cancer; 2006 Apr 15;118(8):1972-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22).
  • Subungual exostosis is a benign bone- and cartilage-producing tumor occurring in the hands and feet of children and young adults.
  • The recent identification of a recurrent chromosomal translocation t(X;6)(q24-q26;q15-21) in short-term-cultured tumor cells strongly suggests that subungual exostosis is a neoplastic lesion caused by rearrangement of genes in the two breakpoints.
  • To identify the genes that are critical for neoplastic transformation, we have studied five subungual exostoses by interphase or metaphase FISH.
  • Because collagen molecules are important for tissue remodeling during physiologic growth and differentiation, both COL12A1 and COL4A5 constitute good candidate target genes in the pathogenesis of subungual exostosis.
  • Further investigations on the transcript level are required to elucidate the functional outcome of the t(X;6) translocation in subungual exostoses.
  • [MeSH-major] Cell Transformation, Neoplastic / genetics. Collagen Type IV / genetics. Collagen Type XI / genetics. Exostoses / genetics. Translocation, Genetic

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16284948.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / COL4A5 protein, human; 0 / Collagen Type IV; 0 / Collagen Type XI
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41. García Carmona FJ, Pascual Huerta J, Fernández Morato D: A proposed subungual exostosis clinical classification and treatment plan. J Am Podiatr Med Assoc; 2009 Nov-Dec;99(6):519-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A proposed subungual exostosis clinical classification and treatment plan.
  • Subungual exostosis is a slow-growing, benign outgrowth of normal bone under the nail that affects the nail unit.
  • Clinically, it can appear in combination with a variety of nail disorders, masking the underlying bone condition, which is frequently unrecognized or misdiagnosed.
  • Also, a therapeutic algorithm that describes surgical approaches to the different presentations of this disorder is presented.
  • [MeSH-major] Exostoses / classification. Exostoses / surgery. Nail Diseases / classification. Nail Diseases / surgery

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  • (PMID = 19917738.001).
  • [ISSN] 1930-8264
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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42. Suga H, Mukouda M: Subungual exostosis: a review of 16 cases focusing on postoperative deformity of the nail. Ann Plast Surg; 2005 Sep;55(3):272-5
MedlinePlus Health Information. consumer health - Nail Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subungual exostosis: a review of 16 cases focusing on postoperative deformity of the nail.
  • We reviewed the clinical features of 16 patients who underwent surgery for subungual exostosis, focusing on postoperative deformity of the nail.
  • [MeSH-major] Exostoses / surgery. Nail Diseases / surgery. Postoperative Complications / classification

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  • (PMID = 16106166.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Lemos MC, Kotanko P, Christie PT, Harding B, Javor T, Smith C, Eastell R, Thakker RV: A novel EXT1 splice site mutation in a kindred with hereditary multiple exostosis and osteoporosis. J Clin Endocrinol Metab; 2005 Sep;90(9):5386-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel EXT1 splice site mutation in a kindred with hereditary multiple exostosis and osteoporosis.
  • CONTEXT: Hereditary multiple exostosis (HME) is an autosomal dominant disorder characterized by the development of benign cartilage-capped tumors at the juxta-epiphyseal regions of long bones.
  • OBJECTIVE: The objective of this study was to investigate a three-generation Austrian kindred with HME for EXT1 and EXT2 mutations and for abnormalities of bone mineral density (BMD).
  • Serum biochemical and radiological investigations assessed bone metabolism and BMD.
  • CONCLUSIONS: A novel heterozygous acceptor splice site mutation of EXT1 results in HME that is associated with a low peak bone mass, indicating a possible additional role for EXT1 in bone biology and in regulating BMD.
  • [MeSH-major] DNA, Recombinant. Exostoses, Multiple Hereditary / genetics. Mutation. N-Acetylglucosaminyltransferases / genetics. Osteoporosis / genetics
  • [MeSH-minor] Adolescent. Adult. Bone Density. Case-Control Studies. Cytosine. Female. Femur Neck / metabolism. Guanine. Heterozygote. Humans. Introns. Lumbar Vertebrae / metabolism. Male. Middle Aged. Pedigree. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 15985493.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Recombinant; 5Z93L87A1R / Guanine; 8J337D1HZY / Cytosine; EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1
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44. Moran M, Krieg AH, Boyle RA, Stalley PD: Bilateral total hip arthroplasty in Severe Hereditary Multiple Exostosis: a report of two cases. Hip Int; 2009 Jul-Sep;19(3):279-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral total hip arthroplasty in Severe Hereditary Multiple Exostosis: a report of two cases.
  • Staged bilateral hip arthroplasties were carried out in two patients with osteoarthritis of the hip secondary to the development of hip dysplasia in Hereditary Multiple Exostosis (HME).Both patients had near ankylosis of their hips with pain and difficulty in performing activities of daily living.
  • A proximal femur replacing prosthesis was implanted through an extended trochanteric osteotomy, with preservation of as much proximal bone stock as possible.
  • [MeSH-major] Arthroplasty, Replacement, Hip / methods. Exostoses, Multiple Hereditary / surgery. Osteoarthritis, Hip / surgery

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  • (PMID = 19876885.001).
  • [ISSN] 1724-6067
  • [Journal-full-title] Hip international : the journal of clinical and experimental research on hip pathology and therapy
  • [ISO-abbreviation] Hip Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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45. Crowe F, Sperduti A, O'Connell TC, Craig OE, Kirsanow K, Germoni P, Macchiarelli R, Garnsey P, Bondioli L: Water-related occupations and diet in two Roman coastal communities (Italy, first to third century AD): correlation between stable carbon and nitrogen isotope values and auricular exostosis prevalence. Am J Phys Anthropol; 2010 Jul;142(3):355-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Water-related occupations and diet in two Roman coastal communities (Italy, first to third century AD): correlation between stable carbon and nitrogen isotope values and auricular exostosis prevalence.
  • The reconstruction of dietary patterns in the two Roman imperial age coastal communities of Portus and Velia (I-III AD) by means of stable isotope analysis of bone remains has exposed a certain degree of heterogeneity between and within the two samples.
  • Among skeletal markers of occupation, external auricular exostosis (EAE) has proved to be very informative.
  • [MeSH-major] Ear Diseases / history. Ear, External / pathology. Exostoses / history. Food Habits. Occupational Diseases / history. Occupations. Roman World

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 20014179.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbon Isotopes; 0 / Nitrogen Isotopes
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46. Rao H, Jakheria S: Giant cervical exostosis: a case report with review of literature. J Pediatr Orthop B; 2009 Mar;18(2):103-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant cervical exostosis: a case report with review of literature.
  • We report a rare case of an 8-year-old girl who presented with a giant cauliflower-like autofused pedunculated osteochondroma arising from spinous processes of the second to sixth cervical vertebrae.
  • [MeSH-major] Cervical Vertebrae / pathology. Exostoses / pathology. Osteochondroma / pathology. Spinal Neoplasms / pathology

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  • (PMID = 19238097.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Chikhladze R, Nishnianidze T: [Clinical-morphological aspects of osteochondroma of long bones]. Georgian Med News; 2007 Nov;(152):57-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical-morphological aspects of osteochondroma of long bones].
  • Clinical-morphological aspects of osteochondroma reflect the rate of cancer growth and its prognosis.
  • Verification of bones forms is required to diagnose exostosis.
  • Revealed forms of osteochondroma differ by clinical course which need different surgical approach.
  • The aim of the article was to propose new surgical technique to treat osteochondroma.
  • 71 patients with osteochondroma were examined by clinical and radiological methods.
  • It is concluded, that the growth rate of exostosis depends on: location of the tumor; the structural architecture of the cartilage; enchondral ossifications in tumor.
  • The active and passive stages of osteochondromas in long bones are depicted.
  • [MeSH-major] Bone Neoplasms / pathology. Diaphyses / pathology. Osteochondroma / pathology

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  • (PMID = 18175837.001).
  • [ISSN] 1512-0112
  • [Journal-full-title] Georgian medical news
  • [ISO-abbreviation] Georgian Med News
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Georgia (Republic)
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48. Yoshioka S, Hamada Y, Takata S, Takai H, Yasui N: An Osteochondroma Limiting Flexion of the Proximal Interphalangeal Joint in Hereditary Multiple Exostosis: a Case Report. Hand (N Y); 2010 Sep;5(3):299-302

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An Osteochondroma Limiting Flexion of the Proximal Interphalangeal Joint in Hereditary Multiple Exostosis: a Case Report.
  • We describe a patient in which an osteochondroma, which resulted from hereditary multiple exostoses, limited flexion of the proximal interphalangeal (PIP) joint at birth.

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  • (PMID = 19821079.001).
  • [ISSN] 1558-9455
  • [Journal-full-title] Hand (New York, N.Y.)
  • [ISO-abbreviation] Hand (N Y)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Growth of tumor / Hereditary multiple exostosis / Osteochondroma
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49. Adelowo O, Adebayo S: Hereditary multiple exostosis in two Nigerian siblings. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hereditary multiple exostosis in two Nigerian siblings.
  • Two siblings of an achondroplastic father with radiological features of hereditary multiple exostoses are presented.
  • These two cases are reported to heighten the index of suspicion in diagnosis.

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  • [Cites] Eur J Radiol. 2001 Dec;40(3):208-17 [11731209.001]
  • [Cites] Bull Soc Pathol Exot. 2002 Mar;95(1):20-2 [12012957.001]
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  • (PMID = 21686572.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028090
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50. De Smet L, Degreef I: Bilateral osteochondroma of the scaphoid causing scapholunate dissociation: a case report. Chir Main; 2007 Jun;26(3):141-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bilateral osteochondroma of the scaphoid causing scapholunate dissociation: a case report.
  • A case with bilateral scaphoid osteochondroma (exostosis) with scapholunate dissociation.
  • [MeSH-major] Bone Neoplasms / complications. Dislocations / etiology. Lunate Bone / injuries. Osteochondroma / complications. Scaphoid Bone / injuries. Scaphoid Bone / pathology

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  • (PMID = 17611141.001).
  • [ISSN] 1297-3203
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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51. Ezra N, Tetteh B, Diament M, Jonas AJ, Dickson P: Hereditary multiple exostoses with spine involvement in a 4-year-old boy. Am J Med Genet A; 2010 May;152A(5):1264-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hereditary multiple exostoses with spine involvement in a 4-year-old boy.
  • Hereditary multiple exostosis (HME) is an autosomal dominant disorder characterized by multiple osteochondromas.
  • We describe a case of acute cervical spinal cord compression arising from an exostosis at the lamina of C7 and T1 in a 4-year-old Mexican-American boy with HME.
  • His affected sibling also displayed spinal cord compression because of a bony exostosis.
  • Acute cervical spinal cord compression resulting from osteochondroma is a serious complication of HME. (c) 2010 Wiley-Liss, Inc.
  • [MeSH-major] Exostoses, Multiple Hereditary / diagnosis. Spine / abnormalities


52. Ettl V, Siebenlist S, Rolf O, Kirschner S, Raab P: [Intra-acetabular localisation of an osteochondroma causing subluxation of the hip joint]. Z Orthop Ihre Grenzgeb; 2006 Jan-Feb;144(1):87-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intra-acetabular localisation of an osteochondroma causing subluxation of the hip joint].
  • INTRODUCTION: Intra-acetabular localisation of an osteochondroma causing subluxation of the hip joint is a rare entity in children suffering from multiple hereditary exostoses.
  • CASE: We add the case of an 8-year-old boy with an intraarticular exostosis of the left acetabulum causing subluxation of the hip.
  • Using an anterolateral approach to the hip joint this exostosis was removed surgically together with some extraarticular exostoses of the proximal femur.
  • The hip could be re-centered in combination with an additional varus derotation osteotomy of the proximal femur.
  • CONCLUSION: The operative treatment of an intraarticular exostosis of the hip joint is a difficult and risky surgical procedure.
  • The reported open surgical procedure allowed resection of the intraarticular exostosis in combination with therapy of additional pathologies of the proximal femur.
  • [MeSH-major] Acetabulum / surgery. Exostoses, Multiple Hereditary / complications. Hip Dislocation / etiology
  • [MeSH-minor] Bone Remodeling / physiology. Child. Follow-Up Studies. Hip Joint / pathology. Hip Joint / surgery. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • (PMID = 16498566.001).
  • [ISSN] 0044-3220
  • [Journal-full-title] Zeitschrift für Orthopädie und ihre Grenzgebiete
  • [ISO-abbreviation] Z Orthop Ihre Grenzgeb
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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53. Xu J, Xu CR, Wu H, Pan HL, Tian J: Osteochondroma in the lumbar intraspinal canal causing nerve root compression. Orthopedics; 2009 Feb;32(2):133
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteochondroma in the lumbar intraspinal canal causing nerve root compression.
  • Osteochondromas, which are benign bone tumors that usually develop on long bones, tubular bones, are rarely found in the spine.
  • If they are located in the spinal canal, they may cause nerve root or spinal cord compression, which is a rare but potentially catastrophic manifestation of osteochondromas.
  • No family history of this disease can be traced.
  • T2-weighted magnetic resonance imaging (MRI) of the same level revealed that the L5 nerve root and spinal dura mater were notably compressed by the intraspinal extradural exostosis attached to the right lamina of L5.
  • Considering differential diagnosis, lumbar facet synovial cysts must be excluded as they can also cause myeloradiculopathy with the similar mechanism.
  • Postoperative histopathologic examination confirmed our hypothesis of benign osteochondroma.
  • [MeSH-major] Osteochondroma / complications. Radiculopathy / etiology. Spinal Neoplasms / complications

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  • (PMID = 19301786.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Hussain W, Avedian R, Terry M, Peabody T: Solitary osteochondroma of the proximal femur and femoral acetabular impingement. Orthopedics; 2010 Jan;33(1):51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary osteochondroma of the proximal femur and femoral acetabular impingement.
  • Although osteochondromas can be present within the context of multiple hereditary exostosis, these tumors are overwhelmingly found as isolated lesions.
  • Increased exostotic load associated with multiple hereditary exostosis can lead to limb-length discrepancy, increased femoral anteversion, valgus angulation, and acetabular dysplasia.
  • Despite these observations, the relationship of more common isolated exostoses near the proximal femur and their role in femoral acetabular impingement has never been depicted.
  • Although solitary osteochondromas have been linked with bursal inflammation and pain, compression on neurovascular structures, and malignant degeneration, they have not previously been associated with femoral acetabular impingement.
  • This article presents a novel case of a proximal femoral osteochondroma of the greater trochanter leading to the development and associated symptoms and radiographic findings consistent with hip impingement.
  • A 24-year-old man presented with groin and lower extremity pain thought to be due to an exostosis of the proximal femur.
  • The presence of a proximal femoral exostosis can be associated with the development of femoral acetabular impingement.
  • [MeSH-major] Femoral Neoplasms / complications. Femoral Neoplasms / surgery. Hip Joint / surgery. Joint Instability / surgery. Osteochondroma / complications. Osteochondroma / surgery

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20055356.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Mavrogenis AF, Papagelopoulos PJ, Soucacos PN: Skeletal osteochondromas revisited. Orthopedics; 2008 Oct;31(10)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skeletal osteochondromas revisited.
  • Skeletal osteochondromas or osteocartilaginous exostoses represent the most common of all benign bone tumors and 10% to 15% of all bone tumors.
  • Osteochondromas are solitary or multiple, pedunculated or sessile exophytic outgrowths from the bone surface that are composed of cortical and medullary bone with an overlying hyaline cartilage cap.
  • Marrow and cortical continuity with the underlying parent bone defines the lesion.
  • Osteochondromas usually occur in children or adolescents between 10 and 15 years, and increase in size throughout childhood, ranging from 1 to 10 cm.
  • After adolescence and skeletal maturity, osteochondromas usually exhibit no further growth.
  • In adults, growth or imaging alterations of an osteochondroma suggest the rare diagnosis of malignant transformation; however, extensive growth of osteochondromas without histological evidence of malignancy has been reported
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Diagnostic Imaging / methods. Osteochondroma / diagnosis. Osteochondroma / surgery. Osteotomy / methods

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  • (PMID = 19226005.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 112
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56. Belhocine K, Baiod N, Oussalah A, Cazals-Hatem D, Sauvanet A, Castier Y, Guigui P, Dauzac C, Benayoun L, Pease S, Panis Y, Bellier C, Boucekkine T: [Digestive obstruction: an unusual complication of hereditary multiple exostoses]. Gastroenterol Clin Biol; 2008 Jun-Jul;32(6-7):601-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Digestive obstruction: an unusual complication of hereditary multiple exostoses].
  • Hereditary multiple exostoses is an autosomal dominant bone disorder characterized by multiple cartilaginous tumors growing outward from metaphyses of long bones.
  • Exostosis also called osteochondroma can cause many complications, the most serious being malignant transformation as chondrosarcoma.
  • We report a rare phenotype of this disease in a young male patient who presents digestive symptoms caused by a voluminous degenerated lumbar exostosis with anterior abdominal development.
  • [MeSH-major] Exostoses, Multiple Hereditary / complications. Intestinal Obstruction / etiology


57. Mnif H, Zrig M, Jawahdou R, Sahnoun N, Koubaa M, Abid A: [An unusual localisation of osteochondroma. A single case report]. Chir Main; 2009 Sep;28(4):247-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An unusual localisation of osteochondroma. A single case report].
  • Solitary osteochondroma is a rare benign tumour of the hand arising from the cortical surface.
  • The important differential diagnoses, which should be considered, are Nora's lesion, florid reactive periostitis and Turret exostosis.
  • The authors report an unusual case of osteochondroma of the metacarpal bone with a deficit of extension.
  • The diagnosis was made using imaging techniques and confirmed by histological examination.
  • [MeSH-major] Bone Neoplasms. Metacarpal Bones. Osteochondroma

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  • (PMID = 19482536.001).
  • [ISSN] 1769-6666
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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58. Argin M, Biçeroğlu S, Arkun R, Parildar M: Solitary osteochondroma causing popliteal pseudoaneurysm that presented as a mass lesion. Diagn Interv Radiol; 2007 Dec;13(4):190-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary osteochondroma causing popliteal pseudoaneurysm that presented as a mass lesion.
  • Osteochondromas are the most frequently occurring bone tumors and can rarely lead to vascular complications.
  • A 14-year-old boy with solitary exostosis of the right femur presented with a mass lesion at the posterior aspect of the thigh.
  • [MeSH-major] Aneurysm, False / diagnosis. Bone Neoplasms / diagnosis. Femur / radiography. Osteochondroma / diagnosis. Popliteal Artery / radiography
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Edema / etiology. Humans. Male. Pain / etiology. Tomography, X-Ray Computed

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  • (PMID = 18092290.001).
  • [ISSN] 1305-3825
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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59. Turan Ilica A, Yasar E, Tuba Sanal H, Duran C, Guvenc I: Sciatic nerve compression due to femoral neck osteochondroma: MDCT and MR findings. Clin Rheumatol; 2008 Mar;27(3):403-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sciatic nerve compression due to femoral neck osteochondroma: MDCT and MR findings.
  • Radiographs and computed tomography (CT) revealed an exostosis on the postero-inferior aspect of the left femoral neck.
  • Ultrasonographic examination of left upper thigh and a pelvic magnetic resonance (MR) imaging showed an enlarged sciatic nerve adjacent to the exostosis.
  • Although peroneal and ulnar neuropathies due to the compression by exostosis are reported frequently, imaging findings of sciatic nerve involvement were not well documented in the literature.
  • Multidetector CT and MR findings of a sciatic nerve compression caused by a femoral neck exostosis were presented.
  • [MeSH-major] Bone Neoplasms / complications. Nerve Compression Syndromes / etiology. Osteochondroma / complications. Sciatic Neuropathy / etiology

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  • [Cites] Muscle Nerve. 2000 Aug;23 (8):1290-4 [10918272.001]
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  • (PMID = 17940719.001).
  • [ISSN] 0770-3198
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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60. Abdullah F, Kanard R, Femino D, Ford H, Stein J: Osteochondroma causing diaphragmatic rupture and bowel obstruction in a 14-year-old boy. Pediatr Surg Int; 2006 Apr;22(4):401-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteochondroma causing diaphragmatic rupture and bowel obstruction in a 14-year-old boy.
  • Exostosis, also known as osteochondroma, results from a disorder of the growth-plate where bone grows away from the growth axis and forms an irregular projection.
  • This abnormality most commonly occurs around the femur, scapula, humerus, and ribs.
  • Although hemothorax and diaphragmatic rupture are known complications of exostosis growth, we present herein the first known report of an inward-facing exostosis in a 14-year-old boy with hereditary multiple exostosis causing diaphragmatic rupture and a bowel obstruction requiring operation.
  • Most exostoses are asymptomatic and as such require no further treatment.
  • [MeSH-major] Bone Neoplasms / complications. Diaphragm / pathology. Exostoses, Multiple Hereditary / complications. Intestinal Obstruction / etiology. Osteochondroma / complications
  • [MeSH-minor] Adolescent. Humans. Male. Radiography, Abdominal. Rare Diseases. Rupture, Spontaneous / diagnosis. Rupture, Spontaneous / etiology. Rupture, Spontaneous / surgery. Thoracoscopy / methods. Tomography, X-Ray Computed

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  • (PMID = 16395607.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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61. Faik A, Mahfoud Filali S, Lazrak N, El Hassani S, Hajjaj-Hassouni N: Spinal cord compression due to vertebral osteochondroma: report of two cases. Joint Bone Spine; 2005 Mar;72(2):177-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord compression due to vertebral osteochondroma: report of two cases.
  • Osteochondroma, or exostosis, is the most common of all benign bone tumors.
  • Spinal osteochondromas are uncommon but may cause neurological compromise.
  • We report two cases of spinal cord compression by osteochondromas.
  • One patient was a 17-year-old man with hereditary multiple exostoses who was presented with spastic paraparesis, a sensory level at T3-T4, and a pyramidal syndrome.
  • Vertebral exostosis was suspected by magnetic resonance imaging and confirmed by histological examination.
  • Whereas magnetic resonance imaging suggested a neurofibroma, histological features were those of osteochondroma.
  • Vertebral osteochondromas contribute only 1.3-4.1% of all osteochondromas.
  • The lesion may be solitary or a manifestation of hereditary multiple exostosis.
  • [MeSH-major] Osteochondroma / complications. Spinal Cord Compression / etiology. Spinal Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Decompression, Surgical. Exostoses, Multiple Hereditary / complications. Exostoses, Multiple Hereditary / surgery. Humans. Magnetic Resonance Imaging. Male. Paraplegia / etiology. Treatment Outcome

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  • (PMID = 15797501.001).
  • [ISSN] 1297-319X
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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62. Blazick E, Keeling WB, Armstrong P, Letson D, Back M: Pseudoaneurysm of the superficial femoral artery associated with osteochondroma--a case report. Vasc Endovascular Surg; 2005 Jul-Aug;39(4):355-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pseudoaneurysm of the superficial femoral artery associated with osteochondroma--a case report.
  • Osteochondromas, the most common benign bone tumor, often go undetected and seldom cause significant clinical sequelae.
  • The authors present the case of a 14-year-old male with a distal superficial femoral artery pseudoaneurysm accompanied by distal embolization from a femoral exostosis.
  • [MeSH-major] Aneurysm, False / etiology. Femoral Artery / diagnostic imaging. Femoral Neoplasms / complications. Osteochondroma / complications. Thromboembolism / etiology. Tibial Arteries / diagnostic imaging

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  • (PMID = 16079946.001).
  • [ISSN] 1538-5744
  • [Journal-full-title] Vascular and endovascular surgery
  • [ISO-abbreviation] Vasc Endovascular Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Schnirring-Judge M, Visser J: Resection and reconstruction of an osteochondroma of the hallux: a review of benign bone tumors and a description of an unusual case. J Foot Ankle Surg; 2009 Jul-Aug;48(4):495-505
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resection and reconstruction of an osteochondroma of the hallux: a review of benign bone tumors and a description of an unusual case.
  • Osteochondroma, which is also known as exostosis, is the most common benign bone tumor.
  • Although foot and hand surgeons frequently encounter the subungual exostosis, exostoses commonly localize to other areas of the skeleton as well.
  • In this review, we describe the clinical and diagnostic imaging characteristics of benign bone tumors and, in particular, the osteochondroma and its surgical management.
  • We also report the case of a patient who experienced an unusual pedal digital osteochondroma-like lesion.
  • [MeSH-major] Bone Neoplasms / surgery. Hallux / surgery. Osteochondroma / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Neoplasms, Post-Traumatic / pathology. Young Adult

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  • (PMID = 19577730.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 36
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64. Staals EL, Bacchini P, Mercuri M, Bertoni F: Dedifferentiated chondrosarcomas arising in preexisting osteochondromas. J Bone Joint Surg Am; 2007 May;89(5):987-93
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  • [Title] Dedifferentiated chondrosarcomas arising in preexisting osteochondromas.
  • BACKGROUND: Dedifferentiated chondrosarcomas that arise in osteochondromas are extremely rare lesions for which very little information on treatment and outcome is available in the literature.
  • METHODS: We reviewed the files of the Rizzoli Institute between 1970 and 2002 and identified eighteen patients for whom adequate records and histologic images were available and in whom a high-grade sarcoma had been diagnosed at the same location as a preexisting osteochondroma.
  • Eight lesions occurred in patients with multiple osteochondromas, and ten occurred in patients with solitary lesions.
  • Radiographically, ten lesions appeared as a conventional secondary chondrosarcoma arising in an exostosis, whereas eight showed typical signs of dedifferentiation.
  • CONCLUSIONS: Dedifferentiated chondrosarcoma arising in a preexisting osteochondroma is an extremely rare lesion with a poor prognosis.
  • [MeSH-major] Bone Neoplasms / pathology. Chondrosarcoma / pathology. Osteochondroma / pathology

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  • (PMID = 17473135.001).
  • [ISSN] 0021-9355
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M: Osteochondromas: review of the clinical, radiological and pathological features. In Vivo; 2008 Sep-Oct;22(5):633-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteochondromas: review of the clinical, radiological and pathological features.
  • Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones.
  • This tumor takes the form of a cartilage-capped bony outgrowth on the surface of the bone.
  • The vast majority (85%) of osteochondromas present as solitary, nonhereditary lesions.
  • Approximately 15% of osteochondromas occur as multiple lesions in the context of hereditary multiple osteochondromas (HMOs), a disorder that is inherited in an autosomal dominant manner.
  • However, depending on the location of the osteochondroma, significant symptoms may occur as a result of complications such as fracture, bony deformity, mechanical joint problems and vascular or neurologic compromise.
  • Malignant transformation of osteochondromas can occur later in adulthood but rarely metastasize.
  • The treatment of choice for osteochondroma is surgical unless the skeleton is still immature.
  • Pathogenetic analysis showed that HMOs are caused by mutations in either of two genes: exostosis (multiple)-1 (EXT1), which is located on chromosome 8q24.11-q24.13 or exostosis (multiple)-2 (EXT2), which is located on chromosome 11p11-12.
  • Recently, biallelic inactivation of the EXT1 locus was described in nonhereditary osteochondromas.
  • Reduced EXT1 or EXT2 expression in osteochondromas is associated with disordered cellular distribution of HSPGs, resulting in defective endochondral ossification which is likely to be involved in the formation of osteochondromas.
  • Here the clinical, radiological, pathological and pathogenetic features and the treatment modalities of osteochondroma are reviewed.
  • [MeSH-major] Bone Neoplasms / pathology. Bone Neoplasms / radiography. Osteochondroma / pathology. Osteochondroma / radiography

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  • (PMID = 18853760.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
  • [Number-of-references] 125
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66. Shah ZK, Peh WC, Wong Y, Shek TW, Davies AM: Sarcomatous transformation in diaphyseal aclasis. Australas Radiol; 2007 Apr;51(2):110-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multiple hereditary exostosis (or diaphyseal aclasis) is a condition characterized by the development of multiple osteochondromas.
  • Malignancy typically arises from the cartilaginous cap of the osteochondroma.
  • Radiographs supplemented by computed tomography have an important role in the diagnosis of this condition.
  • [MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic. Exostoses, Multiple Hereditary / pathology. Sarcoma / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 17419854.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 11
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67. Stieber JR, Dormans JP: Manifestations of hereditary multiple exostoses. J Am Acad Orthop Surg; 2005 Mar-Apr;13(2):110-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Manifestations of hereditary multiple exostoses.
  • The solitary osteochondroma, a common pediatric bone tumor, is a cartilage-capped exostosis.
  • Hereditary multiple exostosis is an autosomal dominant disorder manifested by the presence of multiple osteochondromas.
  • Linkage analysis has implicated mutations in the EXT gene family, resulting in an error in the regulation of normal chondrocyte proliferation and maturation that leads to abnormal bone growth.
  • Although exostoses are benign lesions, they are often associated with characteristic progressive skeletal deformities and may cause clinical symptoms.
  • Patients with hereditary multiple exostosis have a slight risk of sarcomatous transformation of the cartilaginous portion of the exostosis.
  • [MeSH-major] Bone and Bones / abnormalities. Exostoses, Multiple Hereditary / complications


68. Altuna Mariezkurrena X, Vea Orte JC, Camacho Arrioaga JJ, Algaba Guimerá J: [Surgical treatment of exostosis in the external auditory canal]. Acta Otorrinolaringol Esp; 2006 Jun-Jul;57(6):257-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of exostosis in the external auditory canal].
  • Exostoses of the external auditory canal are benign bony tumours very common in individuals who frequently participate in aquatic activities.
  • Although most of the cases are asymptomatic, patients with more severe exostoses have recurrent episodes of external otitis and related conductive hearing loss.
  • Patients with more severe canal stenosis, resistant to medical treatment, are candidates for surgical removal of the exostoses.
  • This report reviews our surgical experience with 45 patients, 52 ears, who have undergone surgical removal of exostoses in our Institution during the last 13 years.
  • [MeSH-major] Ear, External / surgery. Exostoses / surgery

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  • (PMID = 16872100.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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69. Fageir MM, Edwards MR, Addison AK: The surgical management of osteochondroma on the ventral surface of the scapula. J Pediatr Orthop B; 2009 Nov;18(6):304-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The surgical management of osteochondroma on the ventral surface of the scapula.
  • Hereditary multiple exostosis is an autosomal dominant disorder characterized by the formation of multiple cartilaginous osteochondromata in the immature skeleton.
  • Ventral scapular osteochondromas have been reported to cause mechanical symptoms and should be considered as a differential to a 'winged' scapula.
  • We report the surgical treatment of two osteochondroma from the ventral surface of the scapula in a 16-year-old girl.
  • Ventral scapular osteochondroma can be successfully treated using the straightforward surgical technique described.
  • [MeSH-major] Bone Neoplasms / surgery. Exostoses, Multiple Hereditary / surgery. Scapula / surgery

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  • (PMID = 19730135.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Florez B, Mönckeberg J, Castillo G, Beguiristain J: Solitary osteochondroma long-term follow-up. J Pediatr Orthop B; 2008 Mar;17(2):91-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary osteochondroma long-term follow-up.
  • A series of 113 osteochondromas were treated in our institution with a long-term follow-up.
  • A retrospective study of the cases of solitary osteochondroma diagnosed and treated in our center from 1970 to 2002 was done.
  • A diagnosis for clinical findings in 73% of the patients was made.
  • Relapse of the exostosis is rare, occurring in an estimated 2% of the resections.
  • The growth of an osteochondroma and/or the presence of pain in older patients suggest possible malignancy.
  • [MeSH-major] Bone Neoplasms / epidemiology. Osteochondroma / epidemiology
  • [MeSH-minor] Adolescent. Adult. Cell Transformation, Neoplastic. Child. Chondrosarcoma / pathology. Chondrosarcoma / surgery. Exostoses / epidemiology. Exostoses / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Spain / epidemiology

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  • (PMID = 18510166.001).
  • [ISSN] 1060-152X
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Avinash KR, Rajagopal KV, Ramakrishnaiah RH, Carnelio S, Mahmood NS: Computed tomographic features of mandibular osteochondroma. Dentomaxillofac Radiol; 2007 Oct;36(7):434-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Computed tomographic features of mandibular osteochondroma.
  • Osteochondroma of the mandibular condyle is fairly rare.
  • Although a panoramic radiograph demonstrated the bony exostosis, a pre-operative CT examination showed the relationship of the tumour to the condyle and also depicted soft-tissue changes secondary to the growth.
  • [MeSH-major] Mandibular Condyle / radiography. Mandibular Neoplasms / radiography. Osteochondroma / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Diagnosis, Differential. Exostoses / radiography. Female. Humans. Mandibular Diseases / radiography. Middle Aged. Radiography, Panoramic. Temporomandibular Joint Disorders / radiography

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  • (PMID = 17881606.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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72. Wagenaar FC, de Vries H: [Diagnostic image. A woman with a growth at a toe nail]. Ned Tijdschr Geneeskd; 2009;153:B355

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 34-year-old woman presented with a progressive subungual swelling of the hallux caused by subungual exostosis.
  • [MeSH-major] Exostoses / pathology. Exostoses / surgery. Hallux / pathology. Hallux / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Treatment Outcome. Young Adult

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  • (PMID = 19785901.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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73. Li Y, Dang TA, Shen J, Perlaky L, Hicks J, Murray J, Meyer W, Chintagumpala M, Lau CC, Man TK: Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondroma. Proteomics; 2006 Jun;6(11):3426-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondroma.
  • Osteosarcoma (OS) is the most common malignant bone tumor in children.
  • To identify a plasma proteomic signature that can detect OS, we used SELDI MS to perform proteomic profiling on plasma specimens from 29 OS and 20 age-matched osteochondroma (OC) patients.
  • The classifier based on this plasma proteomic signature may be useful to differentiate malignant bone cancer from benign bone tumors and for early detection of OS in high-risk individuals.
  • [MeSH-major] Biomarkers, Tumor / blood. Blood Proteins / analysis. Bone Neoplasms / metabolism. Osteosarcoma / metabolism. Proteome / analysis
  • [MeSH-minor] Adolescent. Adult. Child. Diagnosis, Differential. Humans. Osteochondroma / diagnosis. Protein Array Analysis. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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  • (PMID = 16673437.001).
  • [ISSN] 1615-9853
  • [Journal-full-title] Proteomics
  • [ISO-abbreviation] Proteomics
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA81465
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Blood Proteins; 0 / Proteome
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74. Pollock JM, Brogdon BG, Simonds J, Boudreaux C, Nimityongskul P, Massi DS: Multifocal variant of heterotopic ossification. Br J Radiol; 2008 Mar;81(963):e88-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient presented with multiple occurrences of lesions similar to myositis ossificans atraumatica as well as some lesions resembling exostoses/osteochondromas.
  • Several images and histological sections show the range of appearances and locations of her somewhat disparate lesions, including an exostosis with intraspinal extension.
  • [MeSH-major] Ossification, Heterotopic / diagnosis
  • [MeSH-minor] Adolescent. Adult. Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Carpal Bones. Diagnosis, Differential. Elbow. Exostoses / diagnosis. Exostoses / pathology. Female. Hip. Humans. Myositis Ossificans / diagnosis. Myositis Ossificans / pathology. Osteochondroma / diagnosis. Osteochondroma / pathology. Patella. Spinal Neoplasms / diagnosis. Tarsal Bones. Tibia. Tomography, X-Ray Computed

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  • (PMID = 18270291.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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75. Fritz AT, Reddy D, Meehan JP, Jamali AA: Femoral neck exostosis, a manifestation of cam/pincer combined femoroacetabular impingement. Arthroscopy; 2010 Jan;26(1):121-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Femoral neck exostosis, a manifestation of cam/pincer combined femoroacetabular impingement.
  • However, in both cases raised exostoses were evident on the anterolateral femoral neck in the region that commonly comes into contact with the acetabular rim.
  • On the basis of 3-dimensional dynamic reconstructions, we surmise that these exostoses are a direct result of linear contact between the femoral neck and acetabular rim.
  • We recommend that the presence of these exostoses be carefully noted by the arthroscopic hip surgeon and that they be a geographic marker of the zone of contact between the head-neck junction and the acetabular rim and a guide for the area of head osteochondroplasty in combination with appropriate treatment of the acetabular rim.
  • [MeSH-major] Acetabulum / pathology. Arthralgia / etiology. Cartilage, Articular / pathology. Exostoses / etiology. Femur Neck / pathology. Hip Joint / pathology

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  • [Copyright] (c) 2010 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20117636.001).
  • [ISSN] 1526-3231
  • [Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • [ISO-abbreviation] Arthroscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Koplas M, Winalski C, Sundaram M: What's your diagnosis? Osteochondroma with large bursa clinically mimicking malignant transformation. Orthopedics; 2007 Jul;30(7):505, 581-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What's your diagnosis? Osteochondroma with large bursa clinically mimicking malignant transformation.
  • Osteochondroma is a common benign entity.
  • Bursa formation about an osteochondroma may clinically and symptomatically mimic malignant degeneration.
  • Magnetic resonance imaging usually permits unequivocal diagnosis distinguishing between secondary bursitis and malignant degeneration.
  • Magnetic resonance imaging also can differentiate other less common benign complications such as pseudoaneurysm formation caused by the exostosis and fracture at the base of the exostosis.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bursitis / etiology. Femur / pathology. Osteochondroma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 17672146.001).
  • [ISSN] 0147-7447
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Hameetman L, Szuhai K, Yavas A, Knijnenburg J, van Duin M, van Dekken H, Taminiau AH, Cleton-Jansen AM, Bovée JV, Hogendoorn PC: The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions. J Natl Cancer Inst; 2007 Mar 7;99(5):396-406
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions.
  • BACKGROUND: Multiple osteochondromas is a hereditary syndrome that is characterized by the formation of cartilage-capped bony neoplasms (osteochondromas), for which exostosis (multiple)-1 (EXT1) has been identified as a causative gene.
  • However, 85% of all osteochondromas present as solitary (nonhereditary) lesions in which somatic mutations in EXT1 are extremely rare, but loss of heterozygosity and clonal rearrangement of 8q24 (the chromosomal locus of EXT1) are common.
  • We examined whether EXT1 might act as a classical tumor suppressor gene for nonhereditary osteochondromas.
  • METHODS: Eight nonhereditary osteochondromas were subjected to high-resolution array-based comparative genomic hybridization (array-CGH) analysis for chromosome 8q.
  • EXT1 locus-specific fluorescent in situ hybridization (FISH) was performed on nuclei isolated from the three tissue components of osteochondroma (cartilage cap, perichondrium, bony stalk) to examine which parts of the tumor are of clonal origin.
  • RESULTS: Array-CGH analysis of tumor DNA revealed that all eight osteochondromas had a large deletion of 8q; five tumors had an additional small deletion of the other allele of 8q that contained the EXT1 gene.
  • FISH analysis of the cartilage cap, perichondrium, and bony stalk showed that these homozygous EXT1 deletions were present only in the cartilage cap of osteochondroma.
  • CONCLUSION: EXT1 functions as a classical tumor suppressor gene in the cartilage cap of nonhereditary osteochondromas.
  • [MeSH-major] Chromosomes, Human, Pair 8. Gene Deletion. Genes, Tumor Suppressor. N-Acetylglucosaminyltransferases / genetics. Osteochondroma / genetics

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  • (PMID = 17341731.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / RNA, Messenger; 0 / RNA, Neoplasm; EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1
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78. Hassankhani EG: Solitary lower lumbar osteochondroma (spinous process of L3 involvement): a case report. Cases J; 2009;2:9359

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary lower lumbar osteochondroma (spinous process of L3 involvement): a case report.
  • Solitary osteochondromas, which are the most common benign bone tumors of long bones, are rarely found in the vertebral column.
  • The tumor was excised en bloc through a posterior approach and histopathological examination verified the diagnosis of osteocondroma.Osteochondromas are rarely found in the spine, when present in the spine, however, have a predilection for cervical or upper thoracic region arising usually from lamina of vertebrae and are rare in lumbosacral region and very rare at spinous process of the vertebrae.We present a case of osteochondroma locates in lumbar region and spinous process of vertebrae with unusual presentation and was considered clinically as congenital lumbar kyphosis.

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  • [Cites] J Neurosurg. 1999 Oct;91(2 Suppl):219-22 [10505509.001]
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  • (PMID = 20066066.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804730
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79. Downing KL, Crawford EA, Ogilvie CM: Concurrent osteochondroma and osteoblastoma of the proximal humeral shaft. Orthopedics; 2009 Jan;32(1):53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent osteochondroma and osteoblastoma of the proximal humeral shaft.
  • We present what we believe is the first reported case of synchronous osteochondroma and osteoblastoma, occurring in the proximal humerus of a young man.
  • The humeral diaphysis contained a bony exostosis with corticomedullary continuity, consistent with an osteochondroma with a cartilage cap <5 mm thick.
  • Within the proximal portion of the osteochondroma was a 2-cm, edematous, rim-enhancing cystic lesion, concerning for a secondary process such as malignant transformation.
  • On open biopsy, the mass grossly appeared to be a sessile osteochondroma, and was removed with a rongeur.
  • The cystic lesion was curetted out of the bone.
  • Pathology confirmed that the raised lesion was an osteochondroma.
  • The cystic lesion contained osteoblasts in a matrix of osteoid and immature bone, characteristic of an osteoblastoma.
  • The multidisciplinary team agreed that this was an osteoblastoma within an exostosis.
  • We wished to document the extraordinary, simultaneous existence of an osteochondroma and adjacent osteoblastoma in the proximal humerus of a young patient.
  • [MeSH-major] Bone Neoplasms / diagnosis. Humerus / surgery. Neoplasms, Multiple Primary / diagnosis. Osteoblastoma / diagnosis. Osteochondroma / diagnosis

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  • (PMID = 19226029.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Sansón-RíoFrío JA, Santiesteban N, Bahena RI, Villavicencio VV, Martínez-Said H, Padilla RA, Cuellar HM: [Differential diagnosis of multiple hereditary exostosis: presentation of a clinical case with secondary chondrosarcoma and literature review]. Acta Ortop Mex; 2009 Nov-Dec;23(6):376-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Differential diagnosis of multiple hereditary exostosis: presentation of a clinical case with secondary chondrosarcoma and literature review].
  • The multiple enchondromatosis syndromes have many clinical similarities and the differential diagnosis is therefore difficult to make.
  • We present the clinical case of a 38-year-old patient with a diagnosis of multiple familial enchondromatosis who developed a pelvic chondrosarcoma that was treated with external hemipelvectomy.
  • [MeSH-major] Chondrosarcoma. Exostoses, Multiple Hereditary / complications. Femoral Neoplasms
  • [MeSH-minor] Adolescent. Adult. Child. Diagnosis, Differential. Hemipelvectomy / methods. Hip Joint. Humans. Magnetic Resonance Imaging. Male. Pelvic Neoplasms / diagnosis. Prognosis. Sacroiliac Joint. Scoliosis / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 20377004.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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81. Sheff JS, Wang S: Extraskeletal osteochondroma of the foot. J Foot Ankle Surg; 2005 Jan-Feb;44(1):57-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extraskeletal osteochondroma of the foot.
  • An extraskeletal osteochondroma is an infrequently encountered benign cartilaginous tumor with a predilection for the hands and feet that usually does not exceed 3 cm in diameter.
  • This diagnosis can be misleading because it bears the same name as the osseous neoplasm more commonly referred to as an exostosis.
  • The authors present an unusual case of a painful enlarging mass in the foot of a 28-year-old man who was later diagnosed as having an extraskeletal osteochondroma measuring in excess of 4 cm.
  • [MeSH-major] Foot Diseases / pathology. Osteochondroma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 15704084.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Wen W, Zhang Y, Wang Y, Cao L, Wang S, Luo Y: A novel mutation in the EXT1 gene identified in a Han Chinese kindred with hereditary multiple exostosis. Genet Test Mol Biomarkers; 2010 Jun;14(3):371-6
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  • [Title] A novel mutation in the EXT1 gene identified in a Han Chinese kindred with hereditary multiple exostosis.
  • Hereditary multiple exostoses (HME) is an autosomal dominant bone disorder characterized by growth of benign multiple exostoses.
  • The results linked the disease-causing gene to the EXT1 locus on chromosome 8.
  • A novel mutation in EXT1, c.1897delC, which cosegregated with the disease phenotype, was detected.
  • [MeSH-major] Exostoses, Multiple Hereditary / genetics. Family. Mutation. N-Acetylglucosaminyltransferases / genetics

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  • (PMID = 20578942.001).
  • [ISSN] 1945-0257
  • [Journal-full-title] Genetic testing and molecular biomarkers
  • [ISO-abbreviation] Genet Test Mol Biomarkers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1
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83. Romeo S, Hogendoorn PC, Dei Tos AP: Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics. Adv Anat Pathol; 2009 Sep;16(5):307-15
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  • [Title] Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics.
  • Benign cartilaginous tumors of bones, intrinsic to their name, are tumors forming cartilaginous matrix with a clinically benign behavior.
  • In this group, we recognize osteochondromas, (en)chondromas, chondroblastomas, and chondromyxoid fibromas.
  • This group includes common tumors, that is, osteochondroma and (en)chondroma as well as rare tumors such as chondroblastoma and chondromyxoid fibroma.
  • Several benign and malignant tumors may mimic benign cartilaginous tumors of bones.
  • We reviewed the main morphologic features and the differential diagnosis is discussed.
  • The genetics of these tumors is intriguing ranging from single gene event (ie, EXT mutation in multiple osteochondromas) to heterogeneous rearrangements with no recurrent involved chromosomal regions such as in chondroblastoma.
  • [MeSH-major] Bone Neoplasms / genetics. Bone Neoplasms / pathology. Cartilage / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Chondroblastoma / genetics. Chondroblastoma / pathology. Chondroma / genetics. Chondroma / pathology. Diagnosis, Differential. Female. Fibroma / genetics. Fibroma / pathology. Germ-Line Mutation. Humans. Immunohistochemistry. Male. Membrane Proteins / analysis. Membrane Proteins / genetics. Membrane Proteins / metabolism. Middle Aged. N-Acetylglucosaminyltransferases / analysis. N-Acetylglucosaminyltransferases / genetics. N-Acetylglucosaminyltransferases / metabolism. Osteochondroma / genetics. Osteochondroma / pathology. Translocation, Genetic

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  • (PMID = 19700940.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Proteins; EC 2.4.1.- / EXTL2 protein, human; EC 2.4.1.- / N-Acetylglucosaminyltransferases
  • [Number-of-references] 94
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84. Baek HJ, Lee SJ, Cho KH, Choo HJ, Lee SM, Lee YH, Suh KJ, Moon TY, Cha JG, Yi JH, Kim MH, Jung SJ, Choi JH: Subungual tumors: clinicopathologic correlation with US and MR imaging findings. Radiographics; 2010 Oct;30(6):1621-36
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  • Various types of tumors can affect the subungual space, including benign solid tumors (glomus tumor, subungual exostosis, soft-tissue chondroma, keratoacanthoma, hemangioma, lobular capillary hemangioma), benign cystic lesions (epidermal and mucoid cysts), and malignant tumors (squamous cell carcinoma, malignant melanoma).
  • There is some overlap between the US and MR imaging features of subungual tumors; however, certain features can allow accurate diagnosis and expedite management when correlated with clinical and pathologic findings.
  • [MeSH-major] Bone Neoplasms / diagnosis. Glomus Tumor / diagnosis. Magnetic Resonance Imaging / methods. Nail Diseases / diagnosis. Soft Tissue Neoplasms / diagnosis. Ultrasonography / methods
  • [MeSH-minor] Chondroma / diagnosis. Chondroma / ultrasonography. Diagnosis, Differential. Epidermal Cyst / diagnosis. Epidermal Cyst / ultrasonography. Fingers. Hemangioma / diagnosis. Hemangioma / ultrasonography. Humans. Keratoacanthoma / diagnosis. Keratoacanthoma / ultrasonography. Mucoepidermoid Tumor / diagnosis. Mucoepidermoid Tumor / ultrasonography. Toes

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  • [Copyright] © RSNA, 2010.
  • (PMID = 21071379.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
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85. Petratos DV, Bakogiannis KS, Anastasopoulos JN, Matsinos GS, Bessias NK: Popliteal artery pseudoaneurysm secondary to osteochondroma in children and adolescents: a case report and literature review. J Surg Orthop Adv; 2009;18(4):205-10
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  • [Title] Popliteal artery pseudoaneurysm secondary to osteochondroma in children and adolescents: a case report and literature review.
  • Osteochondroma is the most frequent bone tumor and can rarely cause vascular complications.
  • False aneurysms of the popliteal artery due to an osteochondroma are not common in the pediatric population.
  • Radiologic studies revealed an osteochondroma of the distal femur and a pseudoaneurysm of the popliteal fossa.
  • The exostosis was excised and the popliteal artery was repaired by performing a venous patch angioplasty technique.
  • [MeSH-major] Aneurysm, False / etiology. Femoral Neoplasms / complications. Osteochondroma / complications. Popliteal Artery

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  • (PMID = 19995501.001).
  • [ISSN] 1548-825X
  • [Journal-full-title] Journal of surgical orthopaedic advances
  • [ISO-abbreviation] J Surg Orthop Adv
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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86. Khosla A, Parry RL: Costal osteochondroma causing pneumothorax in an adolescent: a case report and review of the literature. J Pediatr Surg; 2010 Nov;45(11):2250-3
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  • [Title] Costal osteochondroma causing pneumothorax in an adolescent: a case report and review of the literature.
  • Costal osteochondroma is a rare but important condition to recognize because of the possibility of serious consequences if not diagnosed and treated promptly.
  • A computed tomographic scan of the chest revealed the cause to be a costal exostosis of the anterior fifth rib.
  • [MeSH-major] Bone Neoplasms / complications. Osteochondroma / complications. Pneumothorax / etiology. Ribs
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Humans. Male. Thoracic Surgery, Video-Assisted / methods. Tomography, X-Ray Computed

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21034955.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Neumann DR, Dorn U: [The interesting case: Nora's lesion of the big toe]. Z Orthop Unfall; 2007 May-Jun;145(3):327-30
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  • In spite of clinically resembling an osteochondroma, a subungual exostosis or a parosteal osteosarcoma, the lesion is characterised by distinct radiological and histological findings.
  • A high rate of local recurrence of up to 50% has been described, but since it is defined as a benign lesion no metastases can be found.
  • [MeSH-major] Bone Neoplasms / pathology. Bone and Bones / pathology. Choristoma / pathology. Foot Deformities, Acquired / pathology. Osteochondroma / pathology. Toes / abnormalities. Toes / pathology

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  • (PMID = 17607632.001).
  • [ISSN] 1864-6697
  • [Journal-full-title] Zeitschrift für Orthopädie und Unfallchirurgie
  • [ISO-abbreviation] Z Orthop Unfall
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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88. Kiralj A, Ilić M, Markov B, Dedić S, Pejaković B, Nalić B: [Chondroma of the skull base and maxilla]. Med Pregl; 2007 Nov-Dec;60(11-12):649-51
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  • [Title] [Chondroma of the skull base and maxilla].
  • INTRODUCTION: Chondromas are uncommon benign tumors of cartilaginous origin.
  • A chondroma is a painless, slow growing tumor causing destruction and exfoliation of teeth.
  • Irregular calcifications may be seen with radiolucencies and then it is an osteochondroma.
  • MATERIAL AND METHODS: We present a patient with a resected and histologically proven chondroma of the skull base and maxilla.
  • DISCUSSION AND CONCLUSION: Chondromyxoid fibroma (CMF) is a rare, benign cartilaginous tumor that often occurs in the metaphyses of proximal tibia, proximal and distal femur and small bones of the foot.
  • The differential diagnosis is wide and includes simple or aneyrismal bone cyst, giant cell tumor, nonossifying fibroma, fibrous dysplasia, enchondroma, chondroblastoma, eosinophilic granuloma and fibrous cortical defect.
  • In the diagnosis of an intracranial chondrocytic tumor, it is important to distinguish it from enchondroma and chondrosarcoma.
  • MR provides a detailed assessment of soft tissue masses of the craniofacial region, while CT offers superior analysis of bone structure involvement.
  • The present case underlines the importance of MR examination in the diagnosis of soft tissue masses in the craniofacial region.
  • [MeSH-major] Chondroma. Maxillary Neoplasms. Skull Base Neoplasms

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  • (PMID = 18666612.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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89. Benali Y, Katthagen BD: Hip subluxation as a complication of arthroscopic debridement. Arthroscopy; 2009 Apr;25(4):405-7
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  • We report a case of a 49-year-old woman who underwent HA for a long ventrolateral labral tear and exostosis of the lateral acetabular rim.
  • The acetabular labrum was resected from the ventral to the lateral aspect; in addition, the exostosis of the lateral acetabular rim was removed.
  • This should admonish us to be cautious in performing resection of the labrum and acetabular exostosis especially in patients with hip dysplasia.
  • Therefore, in dysplastic hip joints with extensive labral tears or degeneration, resection of the labrum and acetabular exostosis should be performed carefully and to the most minimal extent.

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  • (PMID = 19341928.001).
  • [ISSN] 1526-3231
  • [Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • [ISO-abbreviation] Arthroscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Bulycheva IV, Semenova LA, Makhson AN, Myers JB, Zhukov AG, Iskindirova AK: [Osteocartilaginous exostoses (osteochondromas)]. Arkh Patol; 2008 Jan-Feb;70(1):58-61
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  • [Title] [Osteocartilaginous exostoses (osteochondromas)].
  • Osteochondroma is the most common true bone neoplasm formed by a cartilage capped bony projection arising on the external surface of a bone containing a marrow cavity that is continuous with that of the underlying bone.
  • Osteochondromas generally arise in the bones preformed by cartilage.
  • Osteochondromas may be solitary and multiple.
  • The lesion has three layers - perichondrium, cartilage and bone.
  • The cartilage cap is usually less than 2.0 cm thick, superficial chondrocytes are clustered, the ones close to the transition to the bone resemble a growth plate, they are organized into chords and undergo enchondrial ossification.
  • [MeSH-major] Bone Neoplasms / pathology. Cartilage / pathology. Osteochondroma / pathology
  • [MeSH-minor] Exostoses, Multiple Hereditary / pathology. Female. Humans. Male

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  • (PMID = 18368814.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Lectures
  • [Publication-country] Russia (Federation)
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91. Soubeyrand M, de Pinieu G, Biau D, Anract P, Tomeno B: [Bizarre parosteal osteochondromatous proliferation (Nora's lesion): two cases]. Rev Chir Orthop Reparatrice Appar Mot; 2007 Sep;93(5):494-500
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  • The lesion Nora described in 1983 as a bizarre parosteal osteochondromatous proliferation (BPOP) is a member of a group of osteocartilaginous surface lesions.
  • In light of these cases and reports in the literature, the main differential diagnoses of BPOP are exostosis and parosteal osteosarcoma.
  • [MeSH-major] Bone Neoplasms. Humerus. Ilium. Osteochondroma. Periosteum
  • [MeSH-minor] Adult. Bone Plates. Diagnosis, Differential. Exostoses / diagnosis. Exostoses / radiography. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Osteosarcoma / diagnosis. Osteosarcoma / pathology. Time Factors. Tomography, X-Ray Computed

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  • (PMID = 17878841.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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92. Hoberg M, Gradinger R, Rudert M: [Heel pain]. MMW Fortschr Med; 2007 Jun 14;149(24):36-9; quiz 40
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  • Upper heel pain is mostly caused by tendonitis of the Achilles tendon or Haglund exostosis.
  • Only through an exact diagnosis is an adequate and usually conservative therapy possible.
  • [MeSH-major] Achilles Tendon. Bone Cysts / diagnosis. Heel. Pain / etiology. Tendinopathy / diagnosis
  • [MeSH-minor] Calcaneus / injuries. Diagnosis, Differential. Fasciitis, Plantar / diagnosis. Fasciitis, Plantar / therapy. Fractures, Stress / diagnosis. Fractures, Stress / therapy. Heel Spur / diagnosis. Heel Spur / therapy. Humans

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  • (PMID = 17668748.001).
  • [ISSN] 1438-3276
  • [Journal-full-title] MMW Fortschritte der Medizin
  • [ISO-abbreviation] MMW Fortschr Med
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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93. Yoshida A, Ushiku T, Motoi T, Shibata T, Beppu Y, Fukayama M, Tsuda H: Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics. Mod Pathol; 2010 Sep;23(9):1279-88
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  • [Title] Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics.
  • Low-grade osteosarcoma is often confused with benign lesions, and ancillary techniques to enhance diagnostic accuracy have been awaited.
  • This study explores the use of MDM2 and CDK4 immunohistochemistry for the histological diagnosis of low-grade osteosarcoma.
  • We studied 23 cases of low-grade osteosarcoma from 21 patients (parosteal osteosarcoma (n=14), low-grade central osteosarcoma (n=9)) and 40 cases of benign histological mimics (myositis ossificans (n=11), fibrous dysplasia (n=14), osteochondroma (n=6), desmoplastic fibroma (n=1), florid reactive periostitis (n=4), Nora's lesion (n=3), and turret exostosis (n=1)).
  • In contrast, only 1 Nora's lesion out of the 40 miscellaneous benign processes showed immunoreactivity for MDM2 or CDK4.
  • The combination of these two markers thus shows 100% sensitivity and 97.5% specificity for the diagnosis of low-grade osteosarcoma.
  • MDM2 and CDK4 immunostains therefore reliably distinguish low-grade osteosarcoma from benign histological mimics, and their combination may serve as a useful adjunct in this difficult differential diagnosis.
  • [MeSH-major] Biomarkers, Tumor / analysis. Bone Neoplasms / diagnosis. Cyclin-Dependent Kinase 4 / analysis. Osteosarcoma / diagnosis. Proto-Oncogene Proteins c-mdm2 / analysis
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Diseases / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20601938.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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94. Blitz NM, Lopez KT: Giant solitary osteochondroma of the inferior medial calcaneal tubercle: a case report and review of the literature. J Foot Ankle Surg; 2008 May-Jun;47(3):206-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant solitary osteochondroma of the inferior medial calcaneal tubercle: a case report and review of the literature.
  • Small osteophytes are frequently encountered in the foot and ankle, and are not to be confused with true osteochondromas, which are relatively uncommon in this region.
  • Osteochondromas are benign osseous neoplasms with a distinct hyaline cartilage cap originating from the physis and cease growing with skeletal maturity.
  • Osteochondroma are often treated conservatively unless they become symptomatic, painful, demonstrate rapid or new growth, enlarge after skeletal maturity, and/or exhibit signs of malignant transformation.
  • In this report, we present a case of a giant (8 cm x 4.2 cm x 2.1 cm) osteochondroma in an adult occurring on the inferior medial tubercle of the calcaneus that underwent excision, with 3.5 years of follow-up without recurrence.
  • To our knowledge this is the largest osteochondroma affecting the inferior medial tubercle of the calcaneus.
  • This case demonstrates that large osteochondromas may occur in the foot, and also confirms that benign osteochondroma growth may occur in adulthood.
  • A detailed review of osteochondroma occurrence in the foot is presented along with a review of the diagnostic work-up to evaluate for malignant transformation.
  • [MeSH-major] Bone Neoplasms / diagnosis. Calcaneus. Osteochondroma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Severity of Illness Index

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  • (PMID = 18455666.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Waldschmidt U, Slongo T: An unusual cause of paralysis of the peroneal nerve-a case report. J Pediatr Surg; 2010 Jan;45(1):259-61
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  • Peroneal intraneural ganglia are a rare entity of paralysis of the lower limb in children; more often these symptoms occur because of exostosis.
  • Patients with exostosis showed varying outcomes.
  • In children with symptoms suspicious of nerve compression, fast diagnosis and immediate treatment are mandatory to regain best possible recovery.
  • [MeSH-minor] Child. Diagnosis, Differential. Exostoses / diagnosis. Humans. Male. Paresis / etiology. Paresis / pathology. Paresis / surgery. Peroneal Nerve / pathology. Peroneal Nerve / surgery

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20105616.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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96. Bovée JV: Multiple osteochondromas. Orphanet J Rare Dis; 2008;3:3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple osteochondromas.
  • Multiple osteochondromas (MO) is characterised by development of two or more cartilage capped bony outgrowths (osteochondromas) of the long bones.
  • Osteochondromas develop and increase in size in the first decade of life, ceasing to grow when the growth plates close at puberty.
  • The number of osteochondromas may vary significantly within and between families, the mean number of locations is 15-18.
  • Osteochondromas may cause pain, functional problems and deformities, especially of the forearm, that may be reason for surgical removal.
  • The most important complication is malignant transformation of osteochondroma towards secondary peripheral chondrosarcoma, which is estimated to occur in 0.5-5%.
  • MO is an autosomal dominant disorder and is genetically heterogeneous.
  • The diagnosis is based on radiological and clinical documentation, supplemented with, if available, histological evaluation of osteochondromas.
  • If the exact mutation is known antenatal diagnosis is technically possible.
  • MO should be distinguished from metachondromatosis, dysplasia epiphysealis hemimelica and Ollier disease.
  • Osteochondromas are benign lesions and do not affect life expectancy.
  • Management includes removal of osteochondromas when they give complaints.
  • Removed osteochondromas should be examined for malignant transformation towards secondary peripheral chondrosarcoma.
  • For secondary peripheral chondrosarcoma, en-bloc resection of the lesion and its pseudocapsule with tumour-free margins, preferably in a bone tumour referral centre, should be performed.
  • [MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic. Chondrosarcoma / pathology. Exostoses, Multiple Hereditary / diagnosis. Exostoses, Multiple Hereditary / genetics
  • [MeSH-minor] Adult. Animals. Child. Diagnosis, Differential. Female. Genetic Counseling. Humans. Male. Mutation / genetics. N-Acetylglucosaminyltransferases / genetics. Prognosis. Sex Factors

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  • (PMID = 18271966.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
  • [Number-of-references] 86
  • [Other-IDs] NLM/ PMC2276198
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97. Illana Esteban E: [Instruments to cut and make incisions (III). Bone section]. Rev Enferm; 2006 Jun;29(6):54-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Instruments to cut and make incisions (III). Bone section].
  • Cutting tools used on bones fulfill different actions: we distinguish between those which cut bone tissue (dissection of an exostosis, extraction of bone tumors, to remove pieces of bone in order to have access to other body parts, etc.
  • [MeSH-major] Bone and Bones / surgery. General Surgery / instrumentation. Orthopedic Procedures / instrumentation

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  • (PMID = 16875367.001).
  • [ISSN] 0210-5020
  • [Journal-full-title] Revista de enfermería (Barcelona, Spain)
  • [ISO-abbreviation] Rev Enferm
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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98. Chambrone LA, Chambrone L: Bony exostoses developed subsequent to free gingival grafts: case series. Br Dent J; 2005 Aug 13;199(3):146-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bony exostoses developed subsequent to free gingival grafts: case series.
  • Bony exostosis (BE) is described as a benign localised overgrowth of bone of unknown aetiology.
  • Buccal bony exostosis (BBE) development secondary to soft tissue graft procedures has been reported in a small number of cases.
  • The presence of exostoses has been recognised during postoperative visits.
  • Histological examination revealed osseous enlargements compatible with the diagnosis of exostoses at two re-entry procedures.
  • [MeSH-major] Exostoses / etiology. Gingiva / transplantation. Gingivoplasty / adverse effects. Jaw / injuries. Periosteum / injuries

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  • MedlinePlus Health Information. consumer health - Jaw Injuries and Disorders.
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  • (PMID = 16192951.001).
  • [ISSN] 0007-0610
  • [Journal-full-title] British dental journal
  • [ISO-abbreviation] Br Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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99. Tzaveas A, Paraskevas G, Gekas C, Vrettakos A, Antoniou K, Spyridakis I: Anatomical variation of co-existence of 4th and 5th short metacarpal bones, sesamoid ossicles and exostoses of ulna and radius in the same hand: a case report. Cases J; 2008;1(1):281

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anatomical variation of co-existence of 4th and 5th short metacarpal bones, sesamoid ossicles and exostoses of ulna and radius in the same hand: a case report.
  • The existence of exostosis and shortening of metacarpal bones has been described in the literature as part of the hereditary multiple exostosis syndrome but no case has been reported with the co-existence of sesamoid ossicles in the same patient.
  • CASE PRESENTATION: We report a case with co-existence of distal ulnar and radial exostoses, 4th and 5th short metacarpals and sesamoid ossicles in the wrist area.

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  • (PMID = 18959780.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2586011
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100. Hoshi M, Takami M, Hashimoto R, Okamoto T, Yanagida I, Matsumura A, Noguchi K: Spontaneous regression of osteochondromas. Skeletal Radiol; 2007 Jun;36(6):531-4
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous regression of osteochondromas.
  • Spontaneous regression of an osteochondroma is an infrequent event.
  • In this report, two cases with spontaneous regression of osteochondromas are presented.
  • The first case was a solitary osteochondroma of the pedunculated type involving the right proximal humerus in a 7-year-old boy.
  • The second case was a 3-year-old girl with multiple osteochondromatosis, in whom sessile osteochondromas of the right tibia and left fibula regressed over 33 months.
  • Regarding treatment, careful observation may be acceptable for typical osteochondromas, especially in young children.
  • [MeSH-major] Bone Neoplasms / pathology. Osteochondroma / pathology. Osteochondromatosis / pathology

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  • (PMID = 17177023.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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