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1. Andikyan V, Taylor HS: WT1 represses HOX gene expression in the regulation of gynaecologic tumour histologic type. J Cell Mol Med; 2009 Nov-Dec;13(11-12):4522-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] WT1 represses HOX gene expression in the regulation of gynaecologic tumour histologic type.
  • The homeobox gene HOXA10 controls uterine organogenesis during embryonic development and similarly is expressed in endometroid epithelial ovarian cancer.
  • Here we confirmed aberrant regulation of HOXA10 expression in epithelial uterine and ovarian carcinomas.
  • We identified a strong inverse correlation between HOXA10 expression and that of the Wilms' Tumour 1 (WT1) gene in multiple benign and malignant gynaecologic tissues, suggesting functionality of the WT1 sites in the repressor.

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  • (PMID = 19017365.001).
  • [ISSN] 1582-4934
  • [Journal-full-title] Journal of cellular and molecular medicine
  • [ISO-abbreviation] J. Cell. Mol. Med.
  • [Language] ENG
  • [Grant] United States / NICHD NIH HHS / HD / HD036887; United States / NICHD NIH HHS / HD / R29 HD036887; United States / NICHD NIH HHS / HD / U54 HD052668-05; United States / NICHD NIH HHS / HD / U54 HD052668; United States / NICHD NIH HHS / HD / HD062668; United States / NICHD NIH HHS / HD / R01 HD036887
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Repressor Proteins; 0 / WT1 Proteins; 140441-81-2 / HOXA10 protein, human
  • [Other-IDs] NLM/ NIHMS293627; NLM/ PMC3107857
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2. Kelley SP, Ashford RU, Rao AS, Dickson RA: Primary bone tumours of the spine: a 42-year survey from the Leeds Regional Bone Tumour Registry. Eur Spine J; 2007 Mar;16(3):405-9
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  • [Title] Primary bone tumours of the spine: a 42-year survey from the Leeds Regional Bone Tumour Registry.
  • We conducted a review of the Leeds Regional Bone Tumour Registry for primary bone tumours of the spine since establishment in 1958 until year 2000.
  • The Leeds Bone Tumour Registry was reviewed and a total of 2,750 cases of bone tumours and tumour-like cases were analysed.
  • Chordoma was the most frequent tumour in the cervical and sacral regions, while the most common diagnosis overall was multiple myeloma and plasmacytoma.
  • The mean age of presentation was 42 years and pain was the most common presenting symptom, occurring in 95% of malignant and 76% of benign tumours.
  • The establishment of Bone Tumour Registries is the only way that sufficient data on large numbers of these rare tumours can be accumulated to provide a valuable and otherwise unavailable source of information for research, education and clinical follow-up.
  • [MeSH-major] Chordoma / pathology. Multiple Myeloma / pathology. Osteosarcoma / pathology. Plasmacytoma / pathology. Registries / statistics & numerical data. Spinal Neoplasms / pathology

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  • (PMID = 16865376.001).
  • [ISSN] 0940-6719
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2200710
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3. Bocciolini C, Dall'olio D, Cavazza S, Laudadio P: Schwannoma of cervical sympathetic chain: assessment and management. Acta Otorhinolaryngol Ital; 2005 Jun;25(3):191-4
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  • [Title] Schwannoma of cervical sympathetic chain: assessment and management.
  • Schwannoma arising from the cervical sympathetic chain is an uncommon benign nerve tumour.
  • This tumour most often presents as an asymptomatic solitary neck mass, with slow-growing and rare malignant degeneration.
  • Definitive pre-operative diagnosis may be difficult and investigations are not usually helpful.
  • Diagnosis relies on clinical suspicion and confirmation is often obtained by means of surgical pathology.
  • Surgical excision is the treatment of choice for this tumour, with recurrence being rare.
  • The mass was excised through a transverse left cervical skin incision.
  • The pathologic and radiological evaluations, treatment and postoperative complications of this neoplasm are discussed.
  • [MeSH-major] Ganglia, Sympathetic / pathology. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery

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  • (PMID = 16450776.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 13
  • [Other-IDs] NLM/ PMC2639869
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4. Cheah PL, Looi LM: Significance of Bcl-2 and Bax proteins in cervical carcinogenesis: an immunohistochemical study in squamous cell carcinoma and squamous intraepithelial lesions. Malays J Pathol; 2006 Jun;28(1):1-5
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  • [Title] Significance of Bcl-2 and Bax proteins in cervical carcinogenesis: an immunohistochemical study in squamous cell carcinoma and squamous intraepithelial lesions.
  • Sixteen low grade (LSIL), 22 high grade (HSIL) squamous intraepithelial lesions, 28 invasive (13 stage I and 15 stage II-IV) squamous cell carcinoma (SCC) and 15 benign cervices were immunohistochemically studied for involvement of Bcl-2 and Bax proteins in cervical carcinogenesis.
  • Bcl-2 was upregulated (p < 0.05) in HSIL and Bax in SCC when compared with benign cervical squamous epithelium.
  • Bcl-2 expression was confined to the lower third of the epithelium in the benign cervices and LSIL.
  • SCCs showed "diffuse" (evenly distributed) or "basal" (intensified staining around the periphery of the invading tumour nests) expression of Bcl-2.
  • Benign cervical squamous epithelium, LSIL, HSIL and SCC showed a generally diffuse Bax expression.
  • Thus, Bcl-2 and Bax appeared to be upregulated at different stages of cervical carcinogenesis, Bcl-2 in HSIL and Bax after invasion.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / metabolism. Cervical Intraepithelial Neoplasia / metabolism. Proto-Oncogene Proteins c-bcl-2 / metabolism. Uterine Cervical Neoplasms / metabolism. bcl-2-Associated X Protein / metabolism

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  • (PMID = 17694953.001).
  • [ISSN] 0126-8635
  • [Journal-full-title] The Malaysian journal of pathology
  • [ISO-abbreviation] Malays J Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Malaysia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-2-Associated X Protein
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5. Alonso J, Barbier L, Alvarez J, Romo L, Martín JC, Arteagoitia I, Santamaría J: OK432 (picibanil) efficacy in an adult with cystic cervical lymphangioma. A case report. Med Oral Patol Oral Cir Bucal; 2005 Aug-Oct;10(4):362-6
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  • [Title] OK432 (picibanil) efficacy in an adult with cystic cervical lymphangioma. A case report.
  • Cervical cystic lymphangioma (CCL) is a rare and benign tumour involving congenital and cystic abnormalities derived from lymphatic vessels.
  • We are reporting on a cervical cystic lymphangioma in a male aged 22, treated with an intra-lesion injection of 20 cc with 0.01 mg/cc dilution of OK-432 (picibanil) in physiological serum.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Head and Neck Neoplasms / drug therapy. Lymphangioma, Cystic / drug therapy. Picibanil / therapeutic use. Sclerosing Solutions / therapeutic use

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  • (PMID = 16056191.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Sclerosing Solutions; 39325-01-4 / Picibanil
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6. Montironi R, Mazzucchelli R, Lopez-Beltran A, Martignoni G, Cheng L, Montorsi F, Scarpelli M: Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? Eur Urol; 2008 Dec;54(6):1237-46
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  • [Title] Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity?
  • OBJECTIVES: The term "renal epithelial and stromal tumour" (REST) was proposed recently to encompass the spectrum of findings observed in cystic nephroma (CN) and mixed epithelial and stromal tumour (MEST) of the kidney.
  • Rare and unusual morphologic features, such as endometrioid, cervical, and intestinal differentiation, and luteinised ovarian-like stroma, have been described in MEST.
  • Rare aggressive behaviour has been reported for both neoplasms.
  • Even though an aggressive behaviour has been reported in very few cases, in general both neoplasms are considered benign and surgical excision is curative.
  • [MeSH-major] Kidney Neoplasms / classification. Kidney Neoplasms / pathology

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  • [CommentIn] Eur Urol. 2008 Dec;54(6):1245-6 [18006142.001]
  • [CommentIn] Eur Urol. 2009 Jul;56(1):e3 [19167806.001]
  • (PMID = 18006141.001).
  • [ISSN] 0302-2838
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 50
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7. Roijer E, de Bruijn HW, Dahlén U, ten Hoor K, Lundin M, Nilsson K, Soderstrom K, Nilsson O: Squamous cell carcinoma antigen isoforms in serum from cervical cancer patients. Tumour Biol; 2006;27(3):142-52
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  • [Title] Squamous cell carcinoma antigen isoforms in serum from cervical cancer patients.
  • SCCA isoforms were determined before therapy and in follow-up samples from patients with cervical cancer and in serum samples from healthy females.
  • Serum samples from patients with benign skin diseases (psoriasis and eczema) were also selected based on elevated SCCA levels.
  • The dominating serological form of SCCA was free SCCA2 both in healthy controls and in patients with cervical cancer.
  • Both SCCA1 and SCCA2 were elevated in serum from cervical cancer patients and followed the clinical course of the disease during therapy monitoring.
  • SCCA2 did not show improved tumor specificity as compared to SCCA1.
  • [MeSH-major] Antigens, Neoplasm / blood. Carcinoma, Squamous Cell / diagnosis. Enzyme-Linked Immunosorbent Assay. Serpins / blood. Uterine Cervical Neoplasms / diagnosis


8. Nouraei SA, Ismail Y, Ferguson MS, McLean NR, Milner RH, Thomson PJ, Welch AR: Analysis of complications following surgical treatment of benign parotid disease. ANZ J Surg; 2008 Mar;78(3):134-8
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  • [Title] Analysis of complications following surgical treatment of benign parotid disease.
  • BACKGROUND: The objective of the study was to study the incidence of, and risk factors for developing complications following parotidectomy for benign disease, to improve preoperative patient counselling and better inform future surgical management.
  • METHODS: An 11-year retrospective review of 162 parotidectomies for benign disease, collecting and analysing data about presentation, investigations, surgical treatment, postoperative facial nerve function, Frey's syndrome and other surgical complications.
  • The commonest pathology was benign pleomorphic adenoma (43%), followed by Warthin's tumour (30%) and chronic sialadenitis (22%).
  • Operations for Warthin's tumour were associated with an increased risk of dysfunction of the cervical branch of the nerve.

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  • (PMID = 18269474.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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9. Gunny RS, Akhbar N, Connor SE: CT and MRI appearances of inflammatory pseudotumour of the cervical lymph nodes. Br J Radiol; 2005 Jul;78(931):651-4
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  • [Title] CT and MRI appearances of inflammatory pseudotumour of the cervical lymph nodes.
  • Inflammatory pseudotumour (IPT), also known as plasma cell granuloma and inflammatory myofibroblastic tumour, is a rare cause of benign cervical lymphadenopathy which mimics malignant causes of cervical lymphadenopathy.
  • The imaging features of IPT affecting the cervical lymph nodes have not previously been described.
  • [MeSH-major] Granuloma, Plasma Cell / diagnosis. Lymphatic Diseases / diagnosis

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  • (PMID = 15961851.001).
  • [ISSN] 0007-1285
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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10. Kiwerski JE: Surgery and subsequent rehabilitation for cervical spine tumours compressing neural structures. Ortop Traumatol Rehabil; 2008 Nov-Dec;10(6):620-5
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  • [Title] Surgery and subsequent rehabilitation for cervical spine tumours compressing neural structures.
  • Bone malignancies account for merely about 1.5% of all cancers, with a small percentage of these tumours developing in the cervical spine.
  • However, the cervical spine is also the site of benign tumours and neoplasms involving not only bony tissue.
  • Benign tumours do not metastasize but pose a threat to the spinal cord when located intrathecally.
  • The most common cervical spine neoplasms are intradural tumours, usually extramedullary: neurofibromas, meningiomas or gliomas.Indications for surgery depend of the nature and location of the tumour and the consequences of tumour growth.
  • The choice of surgical approach and manner of stabilisation depend primarily on the location of the lesion and the presence of spinal cord compression.Rehabilitation is indicated in all patients, but is particularly important, and at the same time difficult, when the growth of the tumour has resulted in neurological disturbances.
  • Rehabilitation programmes should be designed individually for each patient and should account for the degree of paresis, stage of the underlying malignant disease, survival prognosis, disturbances in the function of other systems, apart from musculoskeletal apparatus, age of the patient, his or her commitment to treatment and other factors.The treatment of malignant neoplasms is usually associated with an unfavourable outcome.
  • [MeSH-major] Cervical Vertebrae / surgery. Paresis / rehabilitation. Spinal Cord Compression / etiology. Spinal Neoplasms / complications. Spinal Neoplasms / surgery

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  • (PMID = 19274865.001).
  • [ISSN] 1509-3492
  • [Journal-full-title] Ortopedia, traumatologia, rehabilitacja
  • [ISO-abbreviation] Ortop Traumatol Rehabil
  • [Language] eng; pol
  • [Publication-type] Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 16
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11. Bradshaw EJ, Wood KM, Hodgkinson P, Lucraft H, Windebank KP: Follicular dendritic cell tumour in a 9-year-old child. Pediatr Blood Cancer; 2005 Oct 15;45(5):725-7
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  • [Title] Follicular dendritic cell tumour in a 9-year-old child.
  • Follicular dendritic cell tumour (FDCT) or sarcoma is a rare tumour first described in 1986.
  • Our patient first presented at 9 years of age with a cervical mass that was removed and revealed an apparently benign, but florid reactive process.
  • [MeSH-major] Dendritic Cells, Follicular / pathology. Head and Neck Neoplasms / pathology. Lymph Nodes / pathology

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  • (PMID = 15926163.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Honig A, Weidler C, Häusler S, Krockenberger M, Buchholz S, Köster F, Segerer SE, Dietl J, Engel JB: Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer. Anticancer Res; 2010 May;30(5):1559-64
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  • [Title] Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer.
  • The current study investigated the expression of BMI-I in human specimens of breast, ovarian, endometrial and cervical cancer.
  • BMI-I expression in human specimens of breast, endometrial and cervical cancer was evaluated by IHC and then compared with the respective benign tissues.
  • RESULTS: BMI-I was significantly (p<0.05) overexpressed in human breast, ovarian, endometrial and cervical cancer specimens as compared to benign controls.
  • In human breast cancer samples, BMI-I expression was most pronounced in the invasion front of the tumour.
  • CONCLUSION: The current study showed for the first time that the BMI-I protein is significantly overexpressed in ovarian, endometrial and cervical cancer and may thus be a potential target for novel antitumor therapies.
  • [MeSH-major] Breast Neoplasms / metabolism. Endometrial Neoplasms / metabolism. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Nuclear Proteins / biosynthesis. Nuclear Proteins / physiology. Ovarian Neoplasms / metabolism. Proto-Oncogene Proteins / biosynthesis. Proto-Oncogene Proteins / physiology. Repressor Proteins / biosynthesis. Repressor Proteins / physiology. Uterine Cervical Neoplasms / metabolism
  • [MeSH-minor] Antineoplastic Agents / pharmacology. Cell Differentiation. Female. Humans. Immunohistochemistry / methods. Ki-67 Antigen / biosynthesis. Neoplasm Proteins / metabolism. Phenotype. Polycomb Repressive Complex 1


13. Burduk PK, Dalke K, Szukalski J, Kaźmierczak W, Mierzwiński J: [Cervical sympathetic chain neurilemmoma--a case report]. Otolaryngol Pol; 2006;60(1):101-3

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  • [Title] [Cervical sympathetic chain neurilemmoma--a case report].
  • INTRODUCTION: Neurilemmoma is benign, slowly growing tumour that arise from nerves.
  • Cervical sympathetic chain neurilemmoma is rare.
  • The tumor was first noticed 6 month later, and it was slowly growing.
  • She underwent excision of the tumor through an incision parallel with the anterior border of the strenomastoid muscle.
  • RESULTS: Histology showed the tumour to be a neurilemmoma arising within the cervical sympathetic chain.
  • CONCLUSIONS: Neurilemmomas very rarely arise from the cervical sympathetic chain.
  • [MeSH-major] Ganglia, Sympathetic / pathology. Neurilemmoma / diagnosis. Neurilemmoma / surgery. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / surgery

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  • (PMID = 16821553.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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14. Szentkereszty Z, Szegedi L, Boros M, Sz Kiss S, Gál I, G Kiss G, Sápy P: [Balloon dilatation of cervical anastomosis stricture after subtotal resection of the esophagus]. Orv Hetil; 2006 Dec 17;147(50):2421-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Balloon dilatation of cervical anastomosis stricture after subtotal resection of the esophagus].
  • [Transliterated title] Szubtotális nyelócsó-resectio után kialakult nyaki anastomosisszukület endoszkópos tágítása és annak eredményei.
  • PATIENTS AND METHODS: In a 10 year period 26 patients (22 male, 4 female, mean age of 53.7 years) with stricture of anastomosis between the esophagus and the neo-esophagus after subtotal esophageal resection were dilated endoscopically 82 times.
  • The indication of the resection was tumour in 23 (88.5%) cases, congenital atresia in 2 (7.7%) cases and corrosive disease in one (3.8%) case.
  • The success rate of the dilatation for benign strictures was 95.5%.
  • In the 4 patients with tumour recurrency a stent was also implanted in the stenosis.
  • CONCLUSIONS: The endoscopic dilatation for the treatment of the cervical anastomosis stricture after subtotal esophageal resection is a successful method with a low rate of complications.
  • In cases of tumour recurrency a stent implantation is suggested.

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  • (PMID = 17274188.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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15. Ozturk C, Tezer M, Hamzaoglu A: Solitary osteochondroma of the cervical spine causing spinal cord compression. Acta Orthop Belg; 2007 Feb;73(1):133-6
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  • [Title] Solitary osteochondroma of the cervical spine causing spinal cord compression.
  • Osteochondromas are common benign tumours of bone that often occur in the metaphysodiaphyseal parts of long bones.
  • Radiographs, CT and MRI showed a solitary benign appearing expansile bone tumour arising from the left vertebral lamina of C-1, spreading to C-2, exerting an eccentric posterolateral compression on the spinal cord in the left part of the spinal canal and causing stenosis of the left neural foramen between C-1 and C-2.
  • [MeSH-major] Cervical Vertebrae / pathology. Osteochondroma / complications. Spinal Cord Compression / etiology. Spinal Neoplasms / complications

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  • (PMID = 17441673.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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16. Happle C, Wetzke M, Hermann EJ, Krauss JK, Hartmann H, Lücke T: ['Cases against KiSS': a diagnostic algorithm for children with torticollis]. Klin Padiatr; 2009 Dec;221(7):430-5
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  • He assumed a functional abnormality of the suboccipital-high cervical spine, resulting in positional preference of the infant;s head.
  • Patients are advised to undergo manual therapy, with pressure applied locally in order to readjust the cervical spine.
  • In both cases, symptoms caused by the tumour were interpreted as "KiSS-syndrome", and appropriate diagnostics and therapy were delayed for months.
  • Whereas most cases are benign, there is a long list of serious differential diagnoses for torticollis in infants.
  • [MeSH-major] Algorithms. Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cervical Vertebrae. Ganglioglioma / diagnosis. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Spinal Diseases / diagnosis. Torticollis / etiology
  • [MeSH-minor] Child, Preschool. Diagnostic Errors. Gait Disorders, Neurologic / etiology. Humans. Infant. Male. Microsurgery. Neoplasm, Residual / diagnosis. Neurologic Examination. Postoperative Complications / diagnosis. Reoperation. Syndrome

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20013566.001).
  • [ISSN] 1439-3824
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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17. Trivedi A, Patel J: A rare case of inflammatory pseudotumour of the submandibular lymphnode. Indian J Otolaryngol Head Neck Surg; 2006 Oct;58(4):408-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inflammatory pseudotumour (IPT), also known as inflammatory myofibroblastic tumour, is a rare cause of benign cervical lymphadenopathy.
  • In its acute clinical presentation it mimics malignant and infective causes of cervical lymphadenopathy.
  • Radical surgery should be avoided before there is histological proof of a malignant tumor.

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  • [Cites] Otolaryngol Head Neck Surg. 1993 Sep;109(3 Pt 1):548-51 [8414578.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2003 Jun;67(6):649-53 [12745159.001]
  • [Cites] AJNR Am J Neuroradiol. 2001 Aug;22(7):1394-7 [11498435.001]
  • (PMID = 23120369.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450364
  • [Keywords] NOTNLM ; Inflammatory pseudotumour / radio-patho findings / steroids / submandibular lymphnode
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18. Zhang YX: Artificial neural networks based on principal component analysis input selection for clinical pattern recognition analysis. Talanta; 2007 Aug 15;73(1):68-75

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  • One data set contains 168 clinical urinary samples, of which 84 specimens are from female thyroid cancer patients (malignant tumour group), and the other samples were collected from healthy women (normal group).
  • In all the specimens, each number of the samples for both uterine cervical cancer patients (malignant tumour group) and healthy females (normal group) is 60, and the other 48 samples were collected from uterine myoma patients (benign tumour group).

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  • (PMID = 19071851.001).
  • [ISSN] 1873-3573
  • [Journal-full-title] Talanta
  • [ISO-abbreviation] Talanta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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19. Pitale A, Andrabi SI, Dolan SJ, Russell CF: Minimally invasive parathyroid exploration for solitary adenoma. Initial experience with an open, 'short incision' approach. Ulster Med J; 2008 May;77(2):115-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: In the vast majority of patients with primary hyperparathyroidism (HPT) the causative pathology is a benign solitary adenoma.
  • The conventional surgical approach for HPT has involved bilateral cervical exploration with attempted identification of all four parathyroids and resection of enlarged glands.
  • However, in recent years new techniques have permitted accurate preoperative localisation of the single parathyroid tumour in many patients.
  • More recently we have progressed to a minimally invasive surgical approach for such individuals in whom the tumour has been localised preoperatively.
  • PATIENTS & METHODS: Between September 2004 and July 2006, 24 patients with proven HPT, underwent focused, unilateral cervical exploration through a short (2.5-3 cm) incision placed low on the appropriate side of the neck.
  • CONCLUSION: A short incision cervical approach for HPT due to solitary adenoma is a viable alternative for appropriately selected patients.
  • [MeSH-major] Adenoma / surgery. Minimally Invasive Surgical Procedures / methods. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods

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  • [Cites] Br J Surg. 1999 Dec;86(12):1563-6 [10594506.001]
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  • (PMID = 18711630.001).
  • [ISSN] 0041-6193
  • [Journal-full-title] The Ulster medical journal
  • [ISO-abbreviation] Ulster Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Northern Ireland
  • [Other-IDs] NLM/ PMC2516437
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20. Lorenzen JC, Godballe C, Kerndrup GB: Lipoblastoma of the neck: a rare cause of respiratory problems in children. Auris Nasus Larynx; 2005 Jun;32(2):169-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They are benign and may be divided in lipoblastomas and lipoblastomatosis.
  • A case with cervical lipoblastoma causing respiratory difficulty is reported, and a clinical characterisation of patients with lipoblastomatous tumours in the neck is presented.
  • He was treated with total surgical resection of a soft and slowly growing tumour in the left side of the neck, extending from the base of the skull to the upper part of the mediastinum.
  • Including the actual case, a review of English literature resulted in the identification of 37 patients with cervical lipoblastoma or lipoblastomatosis.
  • The median age was 25 months (range: 7-75 months), and the median tumour size 9 cm (range: 3-18 cm).
  • [MeSH-major] Head and Neck Neoplasms / complications. Lipoma / complications. Respiration Disorders / etiology

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  • (PMID = 15917175.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 22
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21. Barbanera A, Nina P, Serchi E, Ascanio F: Aggressive recurrence of intra-extradural cervico-thoracic meningothelial meningioma. Acta Neurochir (Wien); 2007 Jan;149(1):83-6; discussion 86
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  • Following subtotal removal, the tumour was histologically classified as meningothelial meningioma and no radiotherapy was recommended.
  • The neuroradiological workup demonstrated that the lesion was stable one year after the operation but, a few months later a tumour recurrence with huge bone destruction was detected.
  • The tumour was totally resected and a circumferential stabilization was performed.
  • The authors discuss the extremely malignant behaviour of a tumour classified as benign.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Cervical Vertebrae. Fatal Outcome. Female. Humans. Middle Aged. Neoplasm Invasiveness. Thoracic Vertebrae

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  • (PMID = 17171297.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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22. Widziszowska A, Namysłowski G, Hajduk A, Lange D: [Parapharyngeal oncocytoma of the parotid gland--case report]. Otolaryngol Pol; 2007;61(2):195-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Oncocytoma is a rare, benign salivary gland tumour with slowly course.
  • On the basis of physical examination and preoperative radiologic studies (computed tomography scan of nasopharynx, magnetic resonance imaging, Doppler ultrasonography of carotid and vertebral arteries) the extensiveness of the tumour was determined and the surgical procedure was undertaken.
  • The removal of a whole tumour was performed through a cervical--transpharyngeal approach with midline mandibulotomy.
  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / surgery. Parotid Neoplasms / diagnosis. Parotid Neoplasms / surgery

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  • (PMID = 17668810.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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23. Ahmed M, Bin Yousef H, Greer W, Faraz H, Al Sobhi S, Al Zahrani A, Raef H, Al Ghamdi A, Al Kadhi Y, Al Dayel F: Hurthle cell neoplasm of the thyroid gland. ANZ J Surg; 2008 Mar;78(3):139-43
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  • [Title] Hurthle cell neoplasm of the thyroid gland.
  • BACKGROUND: A clinicopathological analysis and long-term follow up of 32 patients with Hurthle cell neoplasm (HCN) was undertaken to contrast the clinical and histological features between benign versus malignant HCN of thyroid and to examine the effect of treatment on the outcome.
  • RESULTS: Seventeen patients were classified as malignant HCN (MHCN) and 15 as benign HCN (BHCN).
  • The mean tumour size was 4.43 +/- 0.66 cm for MHCN, and 2.57 +/- 0.32 cm for BHCN (P = 0.03).
  • Multicentric tumour foci were evident in five cases (29%) of MHCN but none among the BHCN (P = 0.03).
  • At neck exploration cervical lymph node dissection was carried out in nine MHCN patients with findings of tumour metastases in 33%.
  • CONCLUSION: Features of MHCN consisted of a large tumour size, unequivocal capsular and vascular invasion, multicentric tumour foci, metastatic lymph node deposits in one-third of patients and presence of distant metastasis in a few.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / surgery. Neoplasm Recurrence, Local / pathology. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Registries. Retrospective Studies. Risk Assessment. Survival Analysis. Thyroidectomy / methods. Treatment Outcome

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  • [CommentIn] ANZ J Surg. 2008 Mar;78(3):115 [18269467.001]
  • (PMID = 18269475.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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24. Fleuret C, Dupré-Goetghebeur D, Person H, Pillette-Delarue M, Conan-Charlet V, Mériot P, Esnault-Lavandier C, Misery L: [Brachioradial pruritus revealing an ependymoma]. Ann Dermatol Venereol; 2009 May;136(5):435-7
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  • We report a case of a brachioradial pruritus revealing an intramedullary tumour.
  • Cervical radiography did not show cervical osteoarthritis.
  • The MRI revealed a bulky cervical intramedullary tumour extending from C2 to C6.
  • After ruling out cavernoma by medullary angiography, surgery was performed and histopathological analysis of the complete lesion revealed a benign ependymoma.
  • DISCUSSION: The case presented underlines the possibility of a brachioradial pruritus revealing an intramedullary tumour.
  • We report the third case of brachioradial pruritus revealing a medullary tumour.
  • CONCLUSION: Atypical brachioradial pruritus complicated by neuropathic pains and disorders should prompt screening for a medullary tumour.
  • [MeSH-major] Ependymoma / radiography. Ependymoma / surgery. Pruritus / etiology. Spinal Neoplasms / radiography. Spinal Neoplasms / surgery
  • [MeSH-minor] Cervical Vertebrae / pathology. Cervical Vertebrae / radiography. Cervical Vertebrae / surgery. Fatal Outcome. Forearm / pathology. Humans. Male. Middle Aged

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  • (PMID = 19442801.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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25. Mumba E, Ali H, Turton D, Cooper K, Grayson W: Human papillomaviruses do not play an aetiological role in Müllerian adenosarcomas of the uterine cervix. J Clin Pathol; 2008 Sep;61(9):1041-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Human papillomaviruses do not play an aetiological role in Müllerian adenosarcomas of the uterine cervix.
  • AIM: To determine if human papillomaviruses (HPVs) play a role in the histogenesis of adenosarcomas of the uterine cervix.
  • METHODS: Nine archival cases of primary cervical adenosarcoma were studied.
  • RESULTS: Neither the benign epithelial components nor the malignant stromal components of the 9 neoplasms harboured nuclear NISH signals for the HPV types investigated.
  • CONCLUSION: HPVs do not appear to play an aetiological role in cervical adenosarcomas.
  • This suggests that a different histogenetic pathway for this rare tumour type must exist.
  • [MeSH-major] Adenosarcoma / virology. DNA, Viral / analysis. Papillomaviridae / genetics. Uterine Cervical Neoplasms / virology
  • [MeSH-minor] Adolescent. Adult. Cervix Uteri / virology. Colposcopy. DNA Primers / genetics. Female. Humans. In Situ Hybridization / methods. Middle Aged. Polymerase Chain Reaction / methods

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  • (PMID = 18552169.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Viral
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26. Scheller K, Scheller C, Becker S, Holzhausen HJ, Schubert J: Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: a case report and review of literature. J Craniomaxillofac Surg; 2010 Dec;38(8):601-4
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  • A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented.
  • Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34-, desmin-, PanCy-, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli).
  • The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge.
  • [MeSH-major] Lymph Nodes / pathology. Nevus, Blue / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Lymphatic Metastasis. Male. Melanoma / pathology. Middle Aged. Neck. Treatment Outcome

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  • [Copyright] Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20223677.001).
  • [ISSN] 1878-4119
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Scotland
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27. Aust W, Bloching M, Holzhausen HJ, Kösling S, Knipping S: [Tuberculosis of the parotid gland]. HNO; 2008 Apr;56(4):425-8
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  • [Transliterated title] Tuberkulose in der Glandula parotidea.
  • The different tumours of the parotid gland can be divided in benign or malignant tumours, regional inflammations and enlarged lymph nodes.
  • We report on a 26-year-old male from Uganda with a slowly growing tumour of the right parotid gland for several months.
  • The CT scan showed a poorly defined intraparotideal tumour.
  • Ultrasonography revealed multiple enlarged cervical lymph nodes.
  • Suspecting a neoplasm of the parotid gland we decided to perform a superficial parotidectomy for histological examination.
  • It must be considered as a differential diagnosis of parotid enlargements.
  • [MeSH-major] Mycobacterium tuberculosis / isolation & purification. Parotid Diseases / diagnosis. Parotid Diseases / microbiology. Tuberculosis / diagnosis. Tuberculosis / microbiology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Parotid Neoplasms / diagnosis

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  • [Cites] HNO. 2002 Apr;50(4):332-8 [12063691.001]
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  • (PMID = 17380314.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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28. Oudidi A, El-Alami MN, Boulaich M, Jazouli N, Kzadri M: [Primary sub-mandibular gland tumours: experience based on 68 cases]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):187-90
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  • [Transliterated title] Les tumeurs primitives de la glande sous-maxillaire: à propos de 68 cas.
  • RESULTS: 68 cases were reviewed comprising 37 benign and 31 malignant tumours (15 females and 33 males).
  • Clinical suspicion of malignancy was associated with symptom of pain, cervical adenopathy, nerve palsy, skin and/or bone invasion.
  • CAT Scans were performedd to assess tumour extent / invasion.
  • Definitive diagnosis was by complete excision and pathological examination.
  • Pleomorphic adenoma (n= 32) were the most frequent benign tumours.
  • Any delay in diagnosis or inappropriate management may result in a poor prognosis for the patient.
  • [MeSH-major] Submandibular Gland Neoplasms / classification. Submandibular Gland Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Early Diagnosis. Female. Humans. Male. Middle Aged. Prognosis

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  • (PMID = 17007195.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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29. Guarino E, Tarantini B, Pilli T, Checchi S, Brilli L, Ciuoli C, Di Cairano G, Mazzucato P, Pacini F: Presurgical serum thyroglobulin has no prognostic value in papillary thyroid cancer. Thyroid; 2005 Sep;15(9):1041-5
Hazardous Substances Data Bank. THYROGLOBULIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We investigated whether serum thyroglobulin determination before surgery for differentiated thyroid carcinoma may have any prognostic value with regard to tumour extension and disease outcome in a retrospective series of 71 patients with papillary thyroid cancer.
  • The same correlation was found in a control group of patients with benign thyroid nodules, confirming that presurgical serum thyroglobulin cannot be used for the differential diagnosis of thyroid carcinoma.
  • Presurgical serum thyroglobulin levels did not differ among patients with tumor limited to thyroid gland or extending to cervical lymph nodes or invading outside the thyroid capsule or metastasising to distant size.
  • [MeSH-major] Carcinoma, Papillary / blood. Carcinoma, Papillary / diagnosis. Thyroglobulin / blood. Thyroid Neoplasms / blood. Thyroid Neoplasms / diagnosis

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  • (PMID = 16187912.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 9002-71-5 / Thyrotropin; 9010-34-8 / Thyroglobulin
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30. Brown L: Pathology of uterine malignancies. Clin Oncol (R Coll Radiol); 2008 Aug;20(6):433-47
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathology of uterine malignancies.
  • This overview covers epithelial, stromal and mesenchymal malignancies of the body of the uterus, excluding the cervix.
  • The distinction of type I and type II endometrial adenocarcinoma with the morphological variants of this tumour is discussed and some molecular aspects are explored.
  • Some types of mixed epithelial and stromal neoplasm are described and contrasted with carcinosarcoma.
  • The concept of stromal sarcoma and high-grade uterine sarcoma is described and an outline of malignant smooth muscle tumours of the uterus includes a description of smooth muscle tumours of uncertain malignant potential and worrying benign smooth muscle lesions.
  • [MeSH-major] Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Endometrial Stromal Tumors / pathology. Female. Humans. Leiomyosarcoma / pathology. Mesoderm / pathology. Neoplasms, Glandular and Epithelial / pathology. Sarcoma / pathology

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  • (PMID = 18499412.001).
  • [ISSN] 0936-6555
  • [Journal-full-title] Clinical oncology (Royal College of Radiologists (Great Britain))
  • [ISO-abbreviation] Clin Oncol (R Coll Radiol)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 233
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31. Eleftheriadis E, Kotzampassi K: Endoprosthesis implantation at the pharyngo-esophageal level: problems, limitations and challenges. World J Gastroenterol; 2006 Apr 7;12(13):2103-8
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  • METHODS: A retrospective evaluation was made for the use of 19 stents positioned at the level of the cervical esophagus: 11 for malignant tumours (7 causing obstruction, 4 complicated by an esophago -tracheal or -cutaneous fistula), and 8 for an acquired benign tracheo-esophageal fistula due to prolonged intubation.
  • The median hospital stay was 3 d for malignant tumour patients and 13.5 d for esophagocutaneous fistula patients.
  • CONCLUSION: Endoprosthesis implantation for malignancy and/or fistula of malignant or benign origin at the level of the cervical esophagus is an easy, well tolerated, safe and effective procedure with no complications or mortality.
  • [MeSH-major] Esophageal Fistula / surgery. Esophageal Neoplasms / surgery. Esophageal Stenosis / surgery. Pharyngeal Neoplasms / surgery. Prosthesis Implantation / methods. Stents

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  • (PMID = 16610065.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4087693
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32. Karonidis A, Rigby HS, Orlando A: Collagenosis Nuchae: a case report of a rare and often misdiagnosed condition. J Plast Reconstr Aesthet Surg; 2007;60(3):320-3
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CN is a rare benign soft tissue tumour that arises from the posterior cervical subcutaneous tissue with predilection for the interscapular and paraspinal regions.
  • The true incidence of CN is probably higher than recognised and CN should be in the differential diagnosis of head and neck lesions.
  • Histological examination is required for the diagnosis.
  • Careful total excision provides cure and accurate diagnosis.
  • [MeSH-major] Fibroma / diagnosis. Head and Neck Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 17293293.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 10
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33. Killampalli VV, Power D, Stirling AJ: Preadolescent presentation of a lumbar chordoma: results of vertebrectomy and fibula strut graft reconstruction at 8 years. Eur Spine J; 2006 Oct;15 Suppl 5:621-5
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  • Chordoma is a tumour of notochordal origin which usually involves the sacrum or skull base presenting in adulthood.
  • Although a benign tumour, mobile segment chordoma is more locally aggressive, more likely to metastasise and has a poorer 5 year survival than sacral and clival lesions.
  • [MeSH-major] Chordoma / diagnosis. Chordoma / surgery. Fibula / transplantation. Lumbar Vertebrae / surgery. Orthopedic Procedures / methods. Spinal Neoplasms / diagnosis. Spinal Neoplasms / surgery

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  • (PMID = 16715306.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC1602195
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34. Bar-Shalom R, Guralnik L, Tsalic M, Leiderman M, Frenkel A, Gaitini D, Ben-Nun A, Keidar Z, Israel O: The additional value of PET/CT over PET in FDG imaging of oesophageal cancer. Eur J Nucl Med Mol Imaging; 2005 Aug;32(8):918-24
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Forty-one FDG PET/CT studies were performed in 32 patients with oesophageal cancer, before surgery (n = 18) or during follow-up after resection of the primary tumour (n = 23).
  • RESULTS: PET/CT had an incremental value over PET for interpretation of 25 of 115 sites (22%), changing the initial characterisation of ten sites to either malignant (n = 1) or benign (n = 9), and defining the precise anatomical location of 15 sites.
  • Fusion was of special value for interpretation of cervical and abdomino-pelvic sites, for disease assessment in loco-regional lymph nodes before surgery and in regions of postoperative anatomical distortion.
  • PET/CT had an impact on the further management of four patients (10%), by detecting nodal metastases that warranted disease upstaging (n = 2) and by excluding disease in sites of benign uptake after surgery (n = 2).
  • [MeSH-major] Esophageal Neoplasms / diagnostic imaging. Fluorodeoxyglucose F18. Image Enhancement / methods. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 15838691.001).
  • [ISSN] 1619-7070
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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35. Lillo FB: Human papillomavirus infection and its role in the genesis of dysplastic and neoplastic lesions of the squamous epithelia. New Microbiol; 2005 Apr;28(2):111-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extensive laboratory and epidemiological evidence demonstrate that human papillomavirus (HPV) is the major cause of squamous cervical carcinoma (SCC), its precursor lesions (cervical intraepithelial neoplasia - CIN) and several other benign and malign clinical manifestations including genital warts, condylomata acuminata, Bowenoid papulosis, vaginal, vulvar and anal intraepithelial neoplasia (VIN and AIN) and carcinoma, penile carcinoma and other squamous neoplasias of the head and neck districts.
  • The relevance and high level of scientific interest surrounding HPVs are related to the oncogenic potential of some viral types belonging to this family and the possibility to influence the incidence of various tumour forms likecervical carcinoma, improving the efficacy of specific screening programs or defining preventive strategies like vaccination.
  • [MeSH-major] Carcinoma, Squamous Cell. Cervical Intraepithelial Neoplasia. Papillomaviridae / pathogenicity. Papillomavirus Infections / virology
  • [MeSH-minor] Female. Humans. Male. Uterine Cervical Neoplasms / prevention & control. Uterine Cervical Neoplasms / virology

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  • (PMID = 16035255.001).
  • [ISSN] 1121-7138
  • [Journal-full-title] The new microbiologica
  • [ISO-abbreviation] New Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 40
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36. Qiu MZ, Xu RH, Ruan DY, Li ZH, Luo HY, Teng KY, Wang ZQ, Li YH, Jiang WQ: Incidence of anemia, leukocytosis, and thrombocytosis in patients with solid tumors in China. Tumour Biol; 2010 Dec;31(6):633-41
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We identified all patients in Cancer Center of Sun Yat-sen University who were diagnosed as solid tumors (breast carcinoma, hepatocellular carcinoma, nasopharyngeal carcinoma, esophageal carcinoma, gastric cancer, cervical carcinoma, endometrial cancer, renal cell carcinoma, and non-small cell lung cancer) between January 2000 and August 2009.
  • We identified 3,180 patients with solid tumors and 285 patients with benign diseases for the final analysis.
  • Leukocytosis was an independent prognostic factor in patients with cervical cancer (P = 0.007).
  • [MeSH-major] Anemia / epidemiology. Breast Neoplasms / complications. Esophageal Neoplasms / complications. Leukocytosis / epidemiology. Liver Neoplasms / complications. Stomach Neoplasms / complications. Thrombocytosis / epidemiology

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  • (PMID = 20652781.001).
  • [ISSN] 1423-0380
  • [Journal-full-title] Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  • [ISO-abbreviation] Tumour Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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37. Biswas D, Saha S, Bera SP: Relative distribution of the tumours of ear, nose and throat in the paediatric patients. Int J Pediatr Otorhinolaryngol; 2007 May;71(5):801-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients 15 years of age or under who presented with a tumour of the otolaryngological region to the department of Otolaryngology were included in this study.
  • Lymphoma of the cervical lymph nodes was not included in this study.
  • RESULTS: Forty-three patients of above age group with a neoplasm of the otolaryngological region were managed in our department, the incidence was 0.5%.
  • The ratio of benign to malignant lesion was 7.6:1.
  • Juvenile nasopharyngeal angiofibroma was the commonest tumour (11 cases, 26%) and embryonal rhabdomyosarcoma was the commonest malignant tumour (3 cases, 7%).
  • The commonest site of neoplasm was the nose and paranasal sinuses (13 cases, 30%).
  • CONCLUSION: A tumour in the otolaryngological site in the paediatric population is rare, the incidence being 1 in 200 new cases in the age group of 15 years or under, 12% of the tumours were malignant.
  • [MeSH-major] Ear Neoplasms / epidemiology. Laryngeal Neoplasms / epidemiology. Paranasal Sinus Neoplasms / epidemiology

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  • (PMID = 17368816.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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38. Conscience I, Jovenin N, Coissard C, Lorenzato M, Durlach A, Grange F, Birembaut P, Clavel C, Bernard P: P16 is overexpressed in cutaneous carcinomas located on sun-exposed areas. Eur J Dermatol; 2006 Sep-Oct;16(5):518-22
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Recently, an increased expression of P16, a cell cycle regulatory tumor suppressor protein, has been demonstrated in cervical squamous neoplasms as a marker of malignancy.
  • OBJECTIVES: Our first aim was to evaluate P16 expression in different types of non-melanoma skin cancers compared with normal skin and benign tumors.
  • Ki67 expression in over 5% of tumour cells was observed in 69% of cutaneous carcinomas (SCC: 54%; BD: 76%; BCC: 80%) versus 16% in the group including SK (30%) and NHS (0%) (p = 0.04).
  • Overexpression of P16 was associated with a high rate of Ki67 positive tumour cells in 23/57 malignant skin tumors (40%).
  • [MeSH-major] Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Skin Neoplasms / metabolism. Ultraviolet Rays

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  • (PMID = 17101472.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Ki-67 Antigen
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39. Hétet JF, Rigaud J, Karam G, Glémain P, Le Normand L, Bouchot O, Le Néel JC, Buzelin JM: [Complications of Bricker ileal conduit urinary diversion: analysis of a series of 246 patients]. Prog Urol; 2005 Feb;15(1):23-9; discussion 29

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Complications des urétérostomies cutanées trans-iléales selon Bricker. Analyse d'une série de 246 patients.
  • Bricker diversion was performed in 73.6% of cases for underlying tumour (prostate, bladder, cervical, colon cancer), and in 26.4% of cases for benign disease (neurogenic bladder radiation bladder bladder exstrophy, incrusting cystitis).

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  • (PMID = 15822387.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 34
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40. Stewart CJ, Little L: Diagnostic value and implications of vimentin expression in normal, reactive and neoplastic endocervical epithelium. Pathology; 2010 Apr;42(3):217-23
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Sixty-two cervical biopsy specimens including normal endocervical epithelium, tubo-endometrioid metaplasia, adenocarcinoma in situ, stratified mucin producing intraepithelial lesions (SMILE), and invasive adenocarcinomas were stained immunohistochemically for vimentin and for p16 protein, Ki-67 and bcl-2.
  • Twelve cases also included areas of high grade cervical intraepithelial neoplasia (CIN).
  • Usually adenocarcinoma in situ was completely negative and therefore vimentin staining sharply distinguished the benign and neoplastic epithelial elements.
  • Most invasive adenocarcinomas were not stained but focal vimentin immunoreactivity was observed in 7/18 cases, and was restricted to small glands and infiltrating cell clusters at the deep (advancing) tumour margin.
  • Therefore vimentin is a useful additional diagnostic marker in the assessment of problematic cervical glandular lesions.
  • The localised re-expression of vimentin at the deep margin of some endocervical adenocarcinomas may be relevant to the process of tumour progression and invasion in these cases.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / analysis. Uterine Cervical Neoplasms / metabolism. Vimentin / biosynthesis
  • [MeSH-minor] Cervical Intraepithelial Neoplasia / metabolism. Cervical Intraepithelial Neoplasia / pathology. Cervix Uteri / metabolism. Cervix Uteri / pathology. Cyclin-Dependent Kinase Inhibitor p16 / biosynthesis. Female. Humans. Immunohistochemistry. Ki-67 Antigen / biosynthesis. Proto-Oncogene Proteins c-bcl-2 / biosynthesis

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  • (PMID = 20350213.001).
  • [ISSN] 1465-3931
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Ki-67 Antigen; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Vimentin
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41. Behtash N, Nazari Z, Fakhrejahani F, Khafaf A, Azar EG: Clinical and histological significance of atypical glandular cell on Pap smear. Aust N Z J Obstet Gynaecol; 2007 Feb;47(1):46-9
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Atypical glandular cell (AGC) on Pap smear is uncommon but may represent a variety of benign and malignant lesions.
  • Forty-one women underwent colposcopy-directed biopsy, endocervical curettage, endometrial sampling and cervical conisation to determine the cytological and histological correlations of AGC on Pap smears.
  • We found eight (19.5%) significant pathological findings including four (9.7%) high-grade squamous intraepithelial lesion, one (2.4%) adenocarcinoma of uterus, one (2.4%) adenocarcinoma of cervix, one (2.4%) squamous cell carcinoma of cervix and one (2.4%) papillary serous tumour of ovary.
  • CONCLUSION: AGC on Pap smear was associated with a clinically significant diagnosis in approximately 20% of our cases.
  • The women with a diagnosis of AGC on cervicovaginal smear are needed to be evaluated at least with colposcopy, endocervical and endometrial curettage.
  • [MeSH-major] Papanicolaou Test. Uterine Cervical Neoplasms / pathology. Vaginal Smears
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Cervix Uteri / pathology. Colposcopy. Conization. Dilatation and Curettage. Endometrium / pathology. Female. Humans. Iran. Middle Aged. Prospective Studies


42. Bobbio A, Mazzeo A, Carbognani P, Rusca M: An unusual case of calcifying fibrous pseudotumour of the cervicothoracic junction. Eur J Cardiothorac Surg; 2008 Nov;34(5):1123-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Calcifying fibrous pseudotumour is a rare benign tumour of soft tissue origin, occasionally encountered in the thoracic cavity; surgical resection is considered the treatment of choice.
  • At surgery the tumour was found to circumferentially entrap the left subclavian artery and its removal involved segmental artery resection and reconstruction by autologous saphenous vein graft.
  • [MeSH-minor] Adult. Cervical Vertebrae. Female. Humans. Thoracic Vertebrae. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18755598.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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43. Shi Y, Liu Z, Peng Z, Liu H, Yang K, Yao X: The diagnosis and treatment of Mullerian adenosarcoma of the uterus. Aust N Z J Obstet Gynaecol; 2008 Dec;48(6):596-600
International Agency for Research on Cancer - Screening Group. diagnostics - A practical manual on visual screening for cervical neoplasia .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The diagnosis and treatment of Mullerian adenosarcoma of the uterus.
  • BACKGROUND: Adenosarcoma of the uterus is one of the rare types of gynaecological malignant tumours.
  • Poor awareness of it among clinicians makes it difficult to diagnose correctly and timely, so it is helpful to enrich and update our knowledge about the tumour with new information of patients.
  • AIM: To improve the level of diagnosis and treatment of Mullerian adenosarcoma of the uterus.
  • METHODS: The medical data of nine patients with Mullerian adenosarcoma of the uterus who were treated from May 1995 to March 2006 in our hospital were analysed retrospectively.
  • RESULTS: Patients typically presented with abnormal uterine bleeding, pain in the lower abdomen, enlargement of the uterus, a mass in the uterine cavity and/or a cervical neoplasm.
  • Microscopically, the glands were lined by benign or atypical glandular epithelium, together with sarcomatous stromal cells which showed characteristic structures of 'periglandular cuff' of increased cellularity and 'intraglandular polypoid projections'.
  • The primary diagnostic rate was 33.3% and the average interval from symptom onset to final diagnosis was 13 months and eight weeks for pre- and postmenopausal patients, respectively.
  • CONCLUSIONS: The most common symptom of adenosarcoma of the uterus is abnormal uterine bleeding.
  • [MeSH-major] Adenosarcoma / diagnosis. Mixed Tumor, Mullerian / diagnosis. Neoplasms, Germ Cell and Embryonal / diagnosis. Uterine Cervical Neoplasms / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Adult. Age Factors. Diagnosis, Differential. Female. Humans. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19133051.001).
  • [ISSN] 1479-828X
  • [Journal-full-title] The Australian & New Zealand journal of obstetrics & gynaecology
  • [ISO-abbreviation] Aust N Z J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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44. Musani MA, Sohail Z, Zafar S, Malik S: Morphological pattern of parotid gland tumours. J Coll Physicians Surg Pak; 2008 May;18(5):274-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All patients were surgically managed and their tumour specimen was sent for histopathology.
  • Classification of individual tumour was based on 1991 World Health Organization Classification.
  • RESULTS: Out of 204 cases, 152 (74.5%) were benign and 52 (25.5%) were malignant.
  • Benign tumours were more common in females whereas malignant tumours were common in males.
  • The mean age of patients was 34 years and 42 years for benign and malignant tumours respectively.
  • Pleomorphic adenoma was most common benign tumor (83.5%), followed by Warthins tumour.
  • The most common malignant tumour was mucoepidermoid carcinoma (60%), followed by adenoid cystic carcinoma.
  • Superficial lobe of parotid gland was the commonest site, 120 benign and all 52 malignant tumours arising from it while 32 benign tumours originated from deep lobe.
  • Parotid swelling for years was main feature of benign tumours, whereas malignant tumours presented with pain, fixation to skin or underlying structure, cervical lymphadenopathy and facial palsy.
  • CONCLUSION: Pleomorphic adenoma was the most common benign tumour and mucoepidermoid carcinoma was most common malignant tumour.
  • [MeSH-major] Parotid Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Fine-Needle. Child. Diagnosis, Differential. Disease Progression. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Morbidity / trends. Neoplasm Staging / methods. Pakistan / epidemiology. Retrospective Studies. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 18541080.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] Pakistan
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45. Kruse AL, Zwahlen RA, Grätz KW: New classification of maxillary ameloblastic carcinoma based on an evidence-based literature review over the last 60 years. Head Neck Oncol; 2009;1:31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The ameloblastic carcinoma is a rare malignant odontogenic tumor which rather occurs in the mandible than in the maxilla.
  • Current classifications do not consider benign histopathological features at the primary and malignant features at the metastatic tumour site.
  • In 54% the primary diagnosis was ameloblastic carcinoma, 34.6% revealed pulmonary metastases, however, only in one patient cervical lymph node metastasis could be found.
  • Nineteen of 26 patients (73,1%) were controlled during a median follow-up time of 54,3 months (6 to 156 months); 6 patients died of disease after a median time of 62,7 months (7 to 156 months) after initial diagnosis.
  • [MeSH-major] Ameloblastoma / classification. Maxillary Neoplasms / classification
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Evidence-Based Medicine. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local

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  • (PMID = 19674470.001).
  • [ISSN] 1758-3284
  • [Journal-full-title] Head & neck oncology
  • [ISO-abbreviation] Head Neck Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2733136
  • [General-notes] NLM/ Original DateCompleted: 20100629
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46. De Verdelhan O, Haegelen C, Carsin-Nicol B, Riffaud L, Amlashi SF, Brassier G, Carsin M, Morandi X: MR imaging features of spinal schwannomas and meningiomas. J Neuroradiol; 2005 Jan;32(1):42-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Spinal schwannomas and meningiomas are mostly benign, intra-dural extramedullary tumours.
  • Concerning the cranio-caudal distribution, half of the cervical tumours were schwannomas, 72% of thoracic lesions were meningiomas and all lumbar tumours were schwannomas.
  • The last significant qualitative item was the "dural tail sign", a dural enhancement or thickening near the tumour.
  • This test allowed diagnosis of schwannomas with a sensitivity of 96.4%, a specificity of 83.3%, a positive predictive value of 87.1%, and a negative predictive value of 95.7%.
  • In conclusion, we consider that a diagnosis of schwannoma should be made when a spinal intradural extramedullary tumour shows hyperintensity on T2W images or intense enhancement without dural tail sign; otherwise meningioma is more probable.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Meningioma / diagnosis. Neurilemmoma / diagnosis. Spinal Neoplasms / diagnosis

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  • (PMID = 15798613.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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47. McCluggage WG, Wilkinson N: Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features. Histopathology; 2005 Sep;47(3):231-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features.
  • The ovary is a common site of metastatic tumour.
  • In many cases of ovarian metastasis there is a known history of malignancy but in other cases the ovarian tumour is the first manifestation of disease.
  • In this review metastatic colorectal, appendiceal, gastric, breast, pancreatic and biliary tract, hepatocellular, renal, transitional and cervical carcinomas and metastatic malignant melanoma involving the ovary are discussed, as is the issue of synchronous ovarian and endometrial carcinomas.
  • Peritoneal tumours, including primary peritoneal carcinoma, mesothelioma and intra-abdominal desmoplastic small round cell tumour, involving the ovary are also discussed, together with a variety of other rare, metastatic ovarian neoplasms.
  • Many metastatic adenocarcinomas involving the ovary, especially those exhibiting mucinous differentiation, closely mimic primary ovarian adenocarcinomas with morphologically bland areas simulating benign and borderline cystadenoma.
  • While immunohistochemistry undoubtedly has a valuable role to play and is paramount in diagnosis in some cases, the results must be interepreted with caution, especially in mucinous tumours, and within the relevant clinical context.
  • We critically discuss the value of immunohistochemistry and associated pitfalls with each tumour type described.
  • [MeSH-major] Adenocarcinoma / secondary. Ovarian Neoplasms / secondary

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  • (PMID = 16115224.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Intermediate Filament Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 68238-35-7 / Keratins
  • [Number-of-references] 114
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48. Bapat U, Mackinnon NA, Spencer MG: Carcinoid tumours of the larynx. Eur Arch Otorhinolaryngol; 2005 Mar;262(3):194-7
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  • The tumour histology and prognosis correlate closely.
  • The typical carcinoid tumours are well differentiated with a benign course.
  • The treatment of choice is adequate total excision of the lesion with neck dissection if there is clinical evidence of cervical lymphadenopathy and a careful follow-up so as to recognise and treat any metastatic spread.
  • [MeSH-major] Carcinoid Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 15164214.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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49. Bala A, Robbins P, Knuckey N, Wong G, Lee G: Spinal chondromyxoid fibroma of C2. J Clin Neurosci; 2006 Jan;13(1):140-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondromyxoid fibroma of bone (CMF) is a rare benign primary bone neoplasm accounting for less than 0.5% of all primary bone neoplasms.
  • The spine is an uncommon site for this tumour, with forty-two cases reported in the modern English literature.
  • This is the second reported case of this rare tumour in this location.
  • [MeSH-major] Bone Neoplasms / pathology. Chondroblastoma / pathology. Fibroma / pathology. Spinal Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Cervical Vertebrae / pathology. Child. Female. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray / methods

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  • (PMID = 16410218.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Scotland
  • [Number-of-references] 39
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50. Lundgren CI, Stalberg P, Grodski S, Sidhu S, Sywak M, Delbridge L: Minimally invasive thyroid surgery for diagnostic excision of solitary thyroid nodules. Asian J Surg; 2007 Oct;30(4):250-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The mean tumour size was 17.3 mm, but the mean size of the thyroid lobe removed was 39.5 mm.
  • Final diagnoses included benign multinodular goitre (26%), follicular adenoma (22%) and carcinoma (20%).
  • It offers a valuable option for diagnostic excision biopsy in patients with thyroid nodules demonstrating an atypical fine-needle biopsy whilst avoiding the need for a standard cervical "collar" incision.

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  • (PMID = 17962127.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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51. Ozdemir N, Bezircioğlu H, Akar O: Giant erosive spinal schwannomas: surgical management. Br J Neurosurg; 2010 Oct;24(5):526-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Therapeutic radical tumour excision without neurologic deterioration is possible in the management.
  • Prognosis is good after total tumour removal.
  • Three of the tumours were located in the cervical region, one in the lumbar region, one in the thoracic region and one in the sacral region.
  • Our experience and other published literature suggest that giant erosive spinal schwannoma has significant features such as local invasive nature together with vertebral body erosion and large size but benign histology, long duration for clinical presentation, common preoperative misdiagnosis and good prognosis after total excision.
  • [MeSH-major] Neurilemmoma / surgery. Spinal Neoplasms / surgery

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  • (PMID = 20515264.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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52. Cai S, Liu H, Li WB, Ouyang YS, Zhang B, Li P, Wang XL, Zhang XY, Li JC, Jiang YX: Ultrasonographic features of medullary thyroid carcinoma and their diagnostic values. Chin Med J (Engl); 2010 Nov;123(21):3074-8
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  • BACKGROUND: Medullary thyroid carcinoma (MTC) is a rare malignant tumour and usually difficult to diagnose with ultrasound.
  • METHODS: We analyzed the sonographic features of 35 MTCs and 50 benign nodules with respect to nodular size, echogenecity, internal content, shape, height/width, border, peripheral halo, calcifications and colour flow pattern.
  • The ratio of long to short axis, echogenecity, internal content and calcifications were also assessed in cervical lymph nodes.
  • The differences in sonographic features between MTCs and benign nodules were analyzed with Chi square test.
  • The combination of multiple sonographic features is helpful, but not definitive, for the diagnosis of MTC.
  • [MeSH-major] Thyroid Neoplasms
  • [MeSH-minor] Adult. Aged. Carcinoma, Neuroendocrine. Female. Humans. Lymphatic Metastasis / diagnosis. Lymphatic Metastasis / ultrasonography. Male. Middle Aged. Young Adult

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  • (PMID = 21162958.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] Thyroid cancer, medullary
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53. Richter C, Baetje M, Bischof A, Makovitzky J, Richter DU, Gerber B, Briese V: Expression of the glycodelin A gene and the detection of its protein in tissues and serum of ovarian carcinoma patients. Anticancer Res; 2007 Jul-Aug;27(4A):2023-5
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Glycodelin A (GdA), also known as placental protein 14 (PP14), has been detected in endometrial, cervical and ovarian carcinoma cells.
  • MATERIALS AND METHODS: We investigated serum, tissue and cyst fluid samples of patients with an ovarian carcinoma in contrast to patients with benign and malignant diseases such as uterine myoma, endometriosis, cervical, uterine and breast cancer, and metastases of bladder and colon carcinoma.
  • CONCLUSION: These results indicate that determination of GdA is not sensitive or specific enough for use as a tumour marker.
  • [MeSH-major] Biomarkers, Tumor / analysis. Gene Expression. Glycoproteins / biosynthesis. Ovarian Neoplasms / diagnosis. Pregnancy Proteins / biosynthesis

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  • (PMID = 17649816.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glycoproteins; 0 / PAEP protein, human; 0 / Pregnancy Proteins; 0 / RNA, Messenger
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54. Sevilla García MA, Llorente Pendás JL, Rodrigo Tapia JP, García Rostán G, Suárez Fente V, Coca Pelaz A, Suárez Nieto C: [Head and neck paragangliomas: revision of 89 cases in 73 patients]. Acta Otorrinolaringol Esp; 2007 Mar;58(3):94-100
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Paragangliomas de cabeza y cuello: revisión de 89 casos en 73 pacientes.
  • PGL are usually clinically benign tumours, although metastasis has been reported and invasive growth can occur in adjacent tissues (<10 %).
  • The surgical approach was evaluated in terms of tumour origin, sequelae, and subsequent evolution, as well as the relapses and their relation with location of the primary tumour.
  • The type A infratemporal fossa approach was used in jugular paragangliomas, the approach was cervical in the carotid and vagal ones and, in the tympanics, a transmeatal or transmastoid approach was performed.
  • CONCLUSIONS: With this article we try to reflect our experience in the treatment of this type of tumour.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Paraganglioma / pathology

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  • (PMID = 17371691.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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55. Scott M, Lyness RW, McCluggage WG: Atypical reactive proliferation of endocervix: a common lesion associated with endometrial carcinoma and likely related to prior endometrial sampling. Mod Pathol; 2006 Mar;19(3):470-4
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We examined the cervical sections in 80 consecutive hysterectomy specimens of endometrial cancer.
  • In 22 cases (27.5%), there was cervical involvement by tumour and these cases were excluded from further analysis.
  • In 20 control cases, comprising hysterectomy specimens for benign conditions, similar changes were not seen.
  • Atypical reactive proliferation involving the endocervical surface is commonly seen in association with endometrial cancer and has the potential to be misinterpreted as endocervical involvement by tumour.
  • The vimentin-negative immunophenotype may be of value in cases where the uterine carcinoma is endometrioid in type as these neoplasms are generally vimentin positive.
  • [MeSH-major] Cervix Uteri / pathology. Endometrial Neoplasms / pathology. Endometrium / pathology

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  • (PMID = 16444192.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vimentin
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56. Newton R, Ziegler J, Casabonne D, Beral V, Mbidde E, Carpenter L, Maxwell Parkin D, Wabinga H, Mbulaiteye S, Jaffe H, Uganda Kaposi's Sarcoma Study Group: A case-control study of cancer of the uterine cervix in Uganda. Eur J Cancer Prev; 2007 Dec;16(6):555-8
MedlinePlus Health Information. consumer health - Cervical Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case-control study of cancer of the uterine cervix in Uganda.
  • As part of an epidemiological study of cancer in Uganda, we investigated social, sexual and reproductive factors in relation to the risk of cancer of the uterine cervix.
  • Patients with all cancer types or with benign tumours were recruited from hospitals in Kampala, Uganda, interviewed about various demographic and lifestyle factors and tested for antibodies against the human immunodeficiency virus-1 (HIV).
  • The case-control study reported here involves 702 HIV-seronegative women, 343 of whom were diagnosed with cancer of the uterine cervix.
  • Key findings were that the risk of cervical cancer increased linearly with the number of pregnancies [chi2(1)=44.7; P<0.0001]; a woman reporting having had 10 or more children had a roughly seven-fold increase in risk of the tumour as compared with women reporting fewer than four pregnancies (odds ratio=7.1; 95% confidence interval 3.8-13.2).
  • [MeSH-major] Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / etiology. Uterine Cervical Neoplasms / epidemiology. Uterine Cervical Neoplasms / etiology

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  • (PMID = 18090129.001).
  • [ISSN] 0959-8278
  • [Journal-full-title] European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
  • [ISO-abbreviation] Eur. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
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57. Hakan T, Celikoğlu E, Aker F, Barişik N: Spinal schwannomatosis: case report of a rare condition. Turk Neurosurg; 2008 Jul;18(3):320-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Schwannomatosis is a rare tumour syndrome characterized by more than one schwannoma without any sign of neurofibromatosis (NF).
  • The patient improved rapidly after removal of the tumour.
  • The histological diagnosis was schwannoma.
  • Laminectomy and tumour excision relieved his complaints.
  • The histological diagnosis was schwannoma.
  • In conclusion, although schwannomatosis is a benign condition, symptomatic tumours should be resected surgically.
  • [MeSH-major] Magnetic Resonance Imaging. Neurilemmoma / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Cervical Vertebrae. Diagnosis, Differential. Humans. Laminectomy. Male. Neurofibromatosis 2 / pathology. Young Adult

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  • (PMID = 18814127.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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58. Dutta R, Kumar A, Handa KK, Dinda AK: Large pedunculated fibrovascular polyp of oesophagus in a young woman. Interact Cardiovasc Thorac Surg; 2009 Aug;9(2):352-3
Hazardous Substances Data Bank. Barium sulfate .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lateral cervical oesophagotomy and excision of a polypoidal mass of 15x6.5x3 cm size was done.
  • FVP is a benign tumour-like condition which can attain an enormous size inside the lumen of the oesophagus.
  • [MeSH-major] Deglutition Disorders / etiology. Esophageal Neoplasms / diagnosis. Polyps / diagnosis

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  • (PMID = 19457898.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
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59. Klein M, Catargi B: VEGF in physiological process and thyroid disease. Ann Endocrinol (Paris); 2007 Dec;68(6):438-48
MedlinePlus Health Information. consumer health - Thyroid Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vascular endothelial growth factor (VEGF) is an important regulator of both benign and malignant disease processes in the thyroid gland.
  • VEGF-A is implicated in tumour growth and metastasis via blood vessels while VEGF-C and VEGF-D, involved in lymphangiogenesis, favour metastasis to the cervical lymph nodes in papillary thyroid carcinomas.
  • High levels of VEGF expression in thyroid tumour cells may correlate with a poorer outcome in papillary thyroid carcinomas.

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  • (PMID = 17991452.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / VEGFA protein, human; 0 / VEGFB protein, human; 0 / VEGFC protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / Vascular Endothelial Growth Factor B; 0 / Vascular Endothelial Growth Factor C; 0 / Vascular Endothelial Growth Factor D; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
  • [Number-of-references] 128
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60. Aydinli U, Ozturk C, Bayram S, Sarihan S, Evrensel T, Yilmaz HS: Evaluation of lung cancer metastases to the spine. Acta Orthop Belg; 2006 Oct;72(5):592-7
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most metastatic spinal lesions (70%) are found at the thoracic level, 20% in the lumbar region, and 10% in the cervical region.
  • A variety of benign and malignant tumours may arise in the lung, but the vast majority is bronchogenic carcinomas (90 to 95%).
  • Between the years 1995 and 2003, 168 lung cancer patients with metastatic spinal tumour who had received radiotherapy and chemotherapy were retrospectively evaluated.
  • The mean survival after diagnosis of vertebral metastasis was 7.1 months.
  • After the diagnosis of vertebral metastasis, the mean survival is seven months.
  • [MeSH-major] Lung Neoplasms / pathology. Spinal Neoplasms / secondary

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  • (PMID = 17152424.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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61. Pepiński W, Sołtyszewski I, Skawrońska M, Rogowski M, Zalewska R, Kozłowski L, Filipowski T, Janica J: Loss of heterozygosity (LOH)--implications for human genetic identification. Folia Histochem Cytobiol; 2009;47(1):105-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • DNA templates were extracted from tumour tissue specimens excised from oncological patients and from reference blood samples.
  • The alteration was detected in 47% of cases with larynx carcinoma, 44% of cases with uveal melanoma, 60% of cases with cervical cancers, one case of liposarcoma G3 and one case od neurofibrosarcoma.
  • In benign tumours (lipoma and fibroma) LOH was also absent.

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  • (PMID = 19419947.001).
  • [ISSN] 1897-5631
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Genetic Markers
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62. Zhou M, Magi-Galluzzi C: Clinicopathological features of prostate cancers detected after an initial diagnosis of 'atypical glands suspicious for cancer'. Pathology; 2010 Jun;42(4):334-8
MedlinePlus Health Information. consumer health - Prostate Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological features of prostate cancers detected after an initial diagnosis of 'atypical glands suspicious for cancer'.
  • BACKGROUND: A diagnosis of 'atypical glands suspicious for cancer' (ATYP) in prostate needle biopsy is associated with approximately a 40-50% risk of detecting prostate cancer in subsequent biopsies.
  • Pathological characteristics of prostate cancer following an initial diagnosis of ATYP are rarely studied.
  • DESIGN: We studied prostate biopsies with an initial diagnosis of ATYP.
  • Number of ATYP foci, presence of concomitant high grade prostatic intraepithelial neoplasia (HGPIN), date and diagnosis of repeat biopsies were recorded.
  • When radical prostatectomy was performed for confirmed prostate cancer, Gleason score, tumour volume, extraprostatic extension, seminal vesicle invasion, lymph node status, and surgical margins of resection status were also recorded.
  • RESULTS: Between 1992 and 2009, 239 patients biopsied at our institution carried a diagnosis of ATYP and underwent repeat follow-up biopsies.
  • Final repeat follow-up diagnoses were: prostate cancer in 122 (51.0%), ATYP in 15 (6.3%), HGPIN in 35 (14.6%), and benign prostatic tissue in 67 (28.0%) cases.
  • One patient presented with metastatic prostate cancer in a cervical lymph node.
  • Tumour volume was low in 42.8%, medium in 49.0%, and extensive in 8.2% of cases.
  • CONCLUSION: Most prostate cancers detected following an initial diagnosis of ATYP are clinically significant.
  • Patients with a diagnosis of ATYP should be followed up aggressively.
  • [MeSH-major] Adenocarcinoma / pathology. Precancerous Conditions / pathology. Prostate / pathology. Prostatic Intraepithelial Neoplasia / pathology. Prostatic Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis

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  • (PMID = 20438405.001).
  • [ISSN] 1465-3931
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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63. Al-Balas H, Omari H, Mustafa Z, Matalka I: Osteoid osteoma of the odontoid process of the axis associated with atlanto-axial fusion. Br J Radiol; 2009 Jul;82(979):e126-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoid osteoma is a primary benign bone tumour with characteristic imaging and pathological features.
  • We report a pathologically proven case of osteoid osteoma of the odontoid process of the second cervical vertebra associated with atlanto-axial fusion.
  • [MeSH-major] Atlanto-Axial Joint / abnormalities. Odontoid Process. Osteoma, Osteoid / diagnosis. Spinal Neoplasms / diagnosis

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  • (PMID = 19541938.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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64. Singh AM, Konjengbam R, Devi SS, Devi NP: Leiomyosarcoma of uterus--a case report. J Indian Med Assoc; 2006 Mar;104(3):142, 144, 147
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leiomyosarcoma of uterus--a case report.
  • Leiomyosarcoma of uterus is a very rare malignant mesenchymal tumour of uterus.
  • It may arise from the uterine myometrium de novo or may be transformed from a pre-existing benign leiomyoma.
  • A 55-year-old female presenting with 20-22 weeks size of uterus and bleeding per vagina was clinically diagnosed as a case of leiomyoma uteri and cervical polyp, was subjected to abdominal hysterectomy.
  • The tumour mass was later confirmed histologically as leiomyosarcoma of uterus presumed to be transformed from pre-existing leiomyoma uteri.
  • [MeSH-major] Hysterectomy. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Uterine Neoplasms / pathology. Uterine Neoplasms / surgery
  • [MeSH-minor] Female. Humans. Middle Aged. Neoplasm Metastasis

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  • (PMID = 16910338.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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