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1. Navas M, Pedrosa-Sánchez M, Martínez-Flórez P, Carrasco R, Pascual JM, Sola RG: [Giant cavernous sinus haemangioma. Case report]. Neurocirugia (Astur); 2009 Oct;20(5):461-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Hemangioma gigante del seno cavernoso. Caso clínico.
  • INTRODUCTION: Intracranial haemangioma is a benign vascular tumor which seldom affects the cavernous sinus region, being it frequently misdiagnosed as a meningioma.
  • The tumor was partially removed through a left pterional approach, leaving an intraselar remnant.
  • This entity represents a neurosurgical challenge, due to the complexity of this anatomical region and the trend of the tumour to bleed during its dissection.
  • [MeSH-minor] Cerebral Angiography. Diagnosis, Differential. Female. Hemangioma, Cavernous, Central Nervous System / complications. Hemangioma, Cavernous, Central Nervous System / diagnosis. Hemangioma, Cavernous, Central Nervous System / epidemiology. Hemangioma, Cavernous, Central Nervous System / radiography. Hemangioma, Cavernous, Central Nervous System / surgery. Humans. Magnetic Resonance Imaging. Meningioma / diagnosis. Middle Aged. Prognosis. Tomography, X-Ray Computed

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  • (PMID = 19830369.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 23
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2. Hałoń A, Patrzałek DJ, Boratyńska M, Wolański M, Hałoń Ł: Kidney donation from a patient with cardiac myxoma: a case report. Transplant Proc; 2008 May;40(4):1073-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A significant percentage of donors may be found among patients primarily suffering from benign neoplasms whose nature does not show malignant potential and do not metastasize.
  • AIM: The aim of this report was to present a successful transplantation of cadaveric kidney grafts from a 61-year-old female donor with a left atrial cardiac myxoma, which initially appeared as an embolic cerebral infarct.
  • CONCLUSION: Patients with myxoma should be accepted as donors, since the risk of dying on the waiting list is greater than the tumor transfer risk.

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  • (PMID = 18555118.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Pascual-Castroviejo I, Pascual-Pascual SI, Viaño J, Velázquez-Fragua R, Carceller-Benito F, Gutiérrez-Molina M, Morales-Bastos C: [Cerebral hemisphere tumours in neurofibromatosis type 1 during childhood]. Rev Neurol; 2010 Apr 16;50(8):453-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cerebral hemisphere tumours in neurofibromatosis type 1 during childhood].
  • AIM: To present seven tumors of the cerebral hemispheres in 6 children with neurofibromatosis type 1 (NF1).
  • PATIENTS AND METHODS: Six patients (three males and three females) of 600 cases of a series with NF1 showed features of cerebral hemispheres tumor (seizures, headache and hemiparesis).
  • Six patients had seven tumors (it was because one of them had one tumor in every frontal lobe, both with the same image characteristics), but they did not were removed and they were not studied histologically.
  • The histological study was made to the other five patients and showed that the histological nature corresponded to pilocytic astrocytoma in one patient, neuroepitelial dysembryoplastic tumor in one, polymorphe xanthoastrocytoma in one, neuroectodermic hamartoma in one, and inflammatory chronic non-granulomatose lesion in one.
  • CONCLUSION: The prevalence of the tumors in the cerebral hemispheres is very low (1%) in the patients with NF1.
  • The tumors commonly are histologically benign, and they can be found in peripheral or deep region of the cerebral hemispheres.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebral Cortex / pathology. Neurofibromatosis 1 / pathology


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4. Costa MJ, Makaryus AN, Rosman DR: A rare case of a cardiac papillary fibroelastoma of the pulmonary valve diagnosed by echocardiography. Int J Cardiovasc Imaging; 2006 Apr;22(2):199-203
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  • The majority of primary tumors of the heart are benign with papillary fibroelastomas being the third most common after myxomas and lipomas respectively.
  • Papillary fibroelastomas represent the most common valvular tumor of the heart.
  • Although benign, papillary fibroelastomas have the potential to cause turbulent flow, thrombus formation, and severe cerebral or coronary embolic disease.

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  • (PMID = 16077998.001).
  • [ISSN] 1569-5794
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Ohba S, Yoshida K, Hirose Y, Ikeda E, Kawase T: Early malignant transformation of a petroclival meningothelial meningioma. Neurosurg Rev; 2009 Oct;32(4):495-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor was subtotally removed and was diagnosed to be a meningothelial meningioma.
  • Seven months after surgery, a recurrence of the tumor was confirmed.
  • The diagnosis of this recurrent tumor was an atypical meningioma.
  • The MIB-1 index and the percent of p53 protein-positive cells in the primary tumor were 4.6% and 35.4%, respectively, whereas those of the recurrent tumor were 34.7% and 33.1%, respectively.
  • These results suggest that the present case had a potentially malignant tumor in the early stage, although it had the histological features of benign meningiomas.
  • [MeSH-minor] Cell Transformation, Neoplastic. Cerebral Angiography. DNA / genetics. Female. Gait Disorders, Neurologic. Gene Dosage. Hearing Disorders / etiology. Humans. Ki-67 Antigen / analysis. Magnetic Resonance Imaging. Meningeal Arteries / surgery. Middle Aged. Neoplasm Recurrence, Local. Neurosurgical Procedures. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 19533187.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53; 9007-49-2 / DNA
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6. Blackmon SH, Kassis ES, Ge Y, Goldfarb R, Reardon M: Left atrial myxoma embolus to the renal artery: should a nephrectomy be advised? Ann Thorac Surg; 2010 Jul;90(1):289-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac myxoma represents the most common primary cardiac tumor, which accounts for 75% of all benign cardiac tumors.
  • Although extremely uncommon, the literature contains a number of examples of metastatic myxomata with active growth at the site of embolic implantation, with most cases being cerebral.
  • Excision of the tumor required cardiac autotransplantation and mitral valve replacement.

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20609801.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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7. Davidson L, Fishback D, Russin JJ, Weiss MH, Yu C, Pagnini PG, Zelman V, Apuzzo ML, Giannotta SL: Postoperative Gamma Knife surgery for benign meningiomas of the cranial base. Neurosurg Focus; 2007;23(4):E6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postoperative Gamma Knife surgery for benign meningiomas of the cranial base.
  • The authors analyzed the mid- and long-term results obtained in patients treated with postresection Gamma Knife surgery (GKS) for residual or recurrent benign meningiomas of the cranial base.
  • METHODS: Thirty-six patients with residual or recurrent benign meningiomas of the skull base following one or more surgical procedures underwent GKS.
  • The median tumor volume was 4.1 ml (range 0.8-20 ml) and the median radiation dose to the tumor margin was 16 Gy (range 15-16 Gy).
  • One patient suffered transient cerebral edema 6 months after GKS.
  • Based on imaging documentation, a partial response was seen in five patients (13.9%), the disease remained stable in 30 patients (83.3%), and in one patient (2.8%) there was an increase in tumor size.
  • CONCLUSIONS: Gamma Knife surgery was shown to be an excellent adjunct to resection because of its durable rate of tumor control and low toxicity.

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  • (PMID = 17961043.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Lim SC, Jang SJ: Myxopapillary ependymoma of the fourth ventricle. Clin Neurol Neurosurg; 2006 Feb;108(2):211-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myxopapillary ependymoma is a benign variant of ependymoma, occurring almost exclusively in the cauda equina region of the back.
  • This tumor occurred in the fourth ventricle of a 62-year-old woman.
  • The patient underwent surgical removal of the tumor.
  • Microscopically, the cut sections of the tumor revealed papillary formation surrounding areas containing both hyalinized blood vessels and myxoid degeneration.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Cerebral Ventricle Neoplasms / surgery. Ependymoma / diagnosis. Ependymoma / surgery. Fourth Ventricle

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  • (PMID = 16412846.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 13
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9. Linke R, Voltz R: FDG-pet in paraneoplastic syndromes. Recent Results Cancer Res; 2008;170:203-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • As tumor therapy still is the mainstay of treatment for paraneoplastic syndromes, early diagnosis of the initial tumor or its recurrence is of utmost clinical importance.
  • For finding the associated tumor, the combined use of FDG-PET and CT seems to have the highest sensitivity and may contribute to accurately distinguishing a true tumor or recurrence from benign lesions or physiologic or inflammatory uptake.
  • Further, this approach helps localize the tumor for further management of the patient such as surgery or more invasive diagnostic procedures.
  • Cerebral FDG-PET proved to confirm paraneoplastic encephalitis and may help monitor tumor therapy.

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  • (PMID = 18019628.001).
  • [ISSN] 0080-0015
  • [Journal-full-title] Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
  • [ISO-abbreviation] Recent Results Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 37
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10. Samadi N, Ahmadi SA: Meningioma: a clinicopathological evaluation. Malays J Med Sci; 2007 Jan;14(1):46-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 205(86.1%) cases were benign, 19(8%) atypical and 14(5.9%) malignant.
  • 181(18%) cases were primary and 51(27%) secondary; 35(68%) of the latter benign, 7(14%) atypical and 9(18%) malignant.
  • All intraspinal meningiomas were benign.
  • In benign cranial and spinal types female to male ratios were 1.9: 1 and 1.3: 1 ; while in atypical and malignant types were 1 :1.4 and 1:3.1 respectively.
  • Mean ages were 49.9 for benign.
  • The most frequent site of involvement in all grades of intracranial tumors was cerebral convexity (31.1 %).
  • Female preponderance seen in benign nonrecurrent meningioma became increasingly less prominent and even reversed in recurrent, atypical and malignant forms.
  • Benign recurrent tumors were similar to non-recurrent tumors microscopically.

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  • (PMID = 22593651.001).
  • [ISSN] 1394-195X
  • [Journal-full-title] The Malaysian journal of medical sciences : MJMS
  • [ISO-abbreviation] Malays J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Other-IDs] NLM/ PMC3351217
  • [Keywords] NOTNLM ; Mahmood grading system / WHO grading system / brain tumor / intracranial / intraspinal / meningioma
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11. Mahore A, Chagla A, Goel A: Seeding metastases of a benign intraventricular meningioma along the surgical track. J Clin Neurosci; 2010 Feb;17(2):253-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Seeding metastases of a benign intraventricular meningioma along the surgical track.
  • Seeding metastases of a benign intraventricular meningioma along the surgical track is rare.
  • We report a patient with a benign fibroblastic intraventricular meningioma that had spread along the path of previous surgery; the recurrences as well as the primary tumor were benign.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Lateral Ventricles / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology. Neoplasm Metastasis / pathology. Neoplasm Seeding
  • [MeSH-minor] Contrast Media. Headache / etiology. Humans. Iatrogenic Disease / prevention & control. Intracranial Hypertension / etiology. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / physiopathology. Neurosurgical Procedures / adverse effects. Neurosurgical Procedures / methods. Radiotherapy. Treatment Outcome. Ventriculostomy / adverse effects. Ventriculostomy / methods. Vomiting / etiology

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  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20036547.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Contrast Media
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12. Pauleit D, Stoffels G, Bachofner A, Floeth FW, Sabel M, Herzog H, Tellmann L, Jansen P, Reifenberger G, Hamacher K, Coenen HH, Langen KJ: Comparison of (18)F-FET and (18)F-FDG PET in brain tumors. Nucl Med Biol; 2009 Oct;36(7):779-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of this study was to compare the diagnostic value of positron emission tomography (PET) using [(18)F]-fluorodeoxyglucose ((18)F-FDG) and O-(2-[(18)F]fluoroethyl)-l-tyrosine ((18)F-FET) in patients with brain lesions suspicious of cerebral gliomas.
  • METHODS: Fifty-two patients with suspicion of cerebral glioma were included in this study.
  • The cerebral accumulation of (18)F-FDG was calculated by decay corrected subtraction of the (18)F-FET scan from the (18)F-FET/(18)F-FDG scan.
  • RESULTS: Histology revealed 24 low-grade gliomas (LGG) of World Health Organization (WHO) Grade II and 19 high-grade gliomas (HGG) of WHO Grade III or IV, as well as nine others, mainly benign histologies.
  • The gliomas showed increased (18)F-FET uptake (>normal brain) in 86% and increased (18)F-FDG uptake (>white matter) in 35%. (18)F-FET PET provided diagnostically useful delineation of tumor extent while this was impractical with (18)F-FDG due to high tracer uptake in the gray matter.
  • A local maximum in the tumor area for biopsy guidance could be identified with (18)F-FET in 76% and with (18)F-FDG in 28%.
  • In some benign lesions like abscesses, increased uptake was observed for both tracers indicating a limited specificity of both techniques.
  • CONCLUSIONS: (18)F-FET PET is superior to (18)F-FDG for biopsy guidance and treatment planning of cerebral gliomas.
  • The uptake of (18)F-FDG is associated with prognosis, but the predictive value is limited and a histological evaluation of tumor tissue remains necessary.
  • Therefore, amino acids like (18)F-FET are the preferred PET tracers for the clinical management of cerebral gliomas.

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  • (PMID = 19720290.001).
  • [ISSN] 1872-9614
  • [Journal-full-title] Nuclear medicine and biology
  • [ISO-abbreviation] Nucl. Med. Biol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / O-(2-fluoroethyl)tyrosine; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 42HK56048U / Tyrosine
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13. Wind JJ, Kerr PB, Sweet JA, Deshmukh VR: Pleomorphic xanthoastrocytoma presenting with life-threatening hemorrhage in a child. J Neurosurg Pediatr; 2009 Feb;3(2):157-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pleomorphic xanthoastrocytomas are glial-based tumors that arise most frequently in young patients and usually follow a more benign and indolent clinical course than their other glial-based tumor counterparts.
  • These tumors most frequently present with seizures, and only 3 previous case reports exist of hemorrhagic tumor as the clinical presentation.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Hemorrhage / diagnosis. Cerebral Hemorrhage / etiology


14. Naydenov E, Tzekov C, Minkin K, Nachev S, Marinov M: [Malignant progression of an anaplastic ganglioglioma into a glioblastoma multiforme--report on two cases and review of the literature]. Khirurgiia (Sofiia); 2009;(2-3):69-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In most of the cases the tumor demonstrates benign clinical behaviour with long-term patients' survival.
  • The tumor was excised partially and the histological result was anaplastic ganglioglioma (World Health Organization - WHO. gr. III).
  • A local tumor recurrence was found and the patient underwent second operative intervention with gross total tumor resection.
  • An involvement of the contralateral cerebral hemisphere was found on control CT-scan ten months later.
  • MRI data for large, heterointense tumor lesion in the left frontal lobe was found.
  • A subtotal tumor removal was made.
  • Data for additional local tumor growth was found on control CT-scan one month later.
  • The tumor behaviour may vary between the patients in spite of the similar histological characteristics which indicates the possible presence of different tumor subtypes.
  • [MeSH-major] Brain Neoplasms / pathology. Ganglioglioma / pathology. Glioblastoma / pathology. Neoplasm Recurrence, Local / pathology


15. Landau D, Avgeropoulos N, Ma J: Cerebral amyloidoma mimicking intracranial tumor: a case report. J Med Case Rep; 2010;4:308
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  • [Title] Cerebral amyloidoma mimicking intracranial tumor: a case report.
  • INTRODUCTION: Cerebral amyloidoma is an infrequently recognized condition that can be confused with a more malignant etiology.
  • He was found to have a cerebral amyloidoma.
  • CONCLUSION: After discovery of the true etiology of his brain abnormality, it was determined that our patient had a more benign disease than was initially feared.
  • Cases such as this demonstrate why consideration of this disorder is important.

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  • (PMID = 20854655.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2946306
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16. Bledsoe JM, Link MJ, Stafford SL, Park PJ, Pollock BE: Radiosurgery for large-volume (> 10 cm3) benign meningiomas. J Neurosurg; 2010 May;112(5):951-6
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  • [Title] Radiosurgery for large-volume (> 10 cm3) benign meningiomas.
  • The average tumor volume was 17.5 cm3 (range 10.1-48.6 cm3); the average tumor margin dose was 15.1 Gy (range 12-18 Gy); and the mean follow-up duration was 70.1 months (range 12-199 months).
  • RESULTS: Tumor control was 99% at 3 years and 92% at 7 years after radiosurgery.
  • Thirty complications after radiosurgery were noted in 27 patients (23%), including 7 cases of seizures, 6 cases of hemiparesis, 5 cases of trigeminal injury, 4 cases of headaches, 3 cases of diplopia, 2 cases each of cerebral infarction and ataxia, and 1 case of hearing loss.
  • CONCLUSIONS: The morbidity associated with SRS for patients with benign meningiomas > 10 cm(3) is greater for supratentorial tumors compared with skull base tumors.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Ataxia / epidemiology. Ataxia / etiology. Cerebral Infarction / epidemiology. Cerebral Infarction / etiology. Female. Follow-Up Studies. Headache / epidemiology. Headache / etiology. Hearing Disorders / epidemiology. Hearing Disorders / etiology. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Retrospective Studies. Supratentorial Neoplasms / pathology. Supratentorial Neoplasms / surgery. Young Adult

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  • [CommentIn] J Neurosurg. 2010 Dec;113(6):1335-6; author reply 1336-7 [20887089.001]
  • (PMID = 19764829.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Kojima H, Yaguchi Y, Moriyama H: Middle ear hemangiona: a case report. Auris Nasus Larynx; 2008 Jun;35(2):255-9
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  • The mass was surgically resected for diagnostic and therapeutic reasons, and pathologic examination revealed a benign hemangioma.
  • The CT, MRI, angiography, and light microscopy findings of the tumor are documented and compared with those a glomus tumor.
  • [MeSH-minor] Cerebral Angiography. Humans. Magnetic Resonance Imaging, Interventional. Male. Middle Aged

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  • (PMID = 17851004.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 16
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18. Bilginer B, Söylemezoğlu F, Cila A, Akalan N: Intraventricular dysembryoplastic neuroepithelial tumor-like neoplasm with disseminated spinal tumor. Turk Neurosurg; 2009 Jan;19(1):69-72
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  • [Title] Intraventricular dysembryoplastic neuroepithelial tumor-like neoplasm with disseminated spinal tumor.
  • Dysembryoplastic neuroepithelial tumor (DNT)- like lesions arise in extracortical locations and behave in a benign fashion similar to that of cortical DNTs.
  • A third ventricular mass lesion with disseminated spinal tumor was detected on his magnetic resonance imaging.
  • The presence of floating neurons in a mucinous matrix, oligodendrocyte-like cells (OLCs) aligning axonal columns and vessels, immunohistochemical profile of the neoplasm in addition to the clinical and radiological manifestations of the patient led to the diagnosis of "DNT-like neoplasm of the third ventricle".
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Magnetic Resonance Imaging. Neoplasms, Neuroepithelial / secondary. Spinal Neoplasms / secondary. Teratoma / secondary

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  • (PMID = 19263357.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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19. Sharma MS, Suri A, Shah T, Ralte A, Sarkar C, Gupta V, Mehta VS: Intraventricular glioneuronal hamartoma: histopathological correlation with magnetic resonance spectroscopy. J Neurooncol; 2005 Sep;74(3):325-8
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  • An 11-year-old male presented with a seizure disorder for one year, with headache and vomiting for 15 days.
  • Radical decompression of the tumor resulted in an excellent outcome.
  • The authors advocate the use of MRS in patients with tuberous sclerosis or neurofibromatosis with suspected hamartomas to distinguish these benign lesions from gliomas prior to a surgical exploration.
  • [MeSH-major] Cerebral Ventricles / pathology. Hamartoma / diagnosis. Magnetic Resonance Spectroscopy

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  • (PMID = 16132521.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Synaptophysin
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20. Yoshida D, Kogiku M, Noha M, Takahashi H, Teramoto A: A case of pleomorphic xanthoastrocytoma presenting with massive tumoral hemorrhage. J Neurooncol; 2005 Jan;71(2):169-71
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  • Pleomorphic xanthoastrocytoma has been generally conceived to be in a benign nature, showing a relatively favorable prognosis.
  • CT and MRI disclosed the presence of a tumor composing of massive intra-tumoral hemorrhage filling the cyst associated with mural nodule in the left frontotemporal lobe.
  • The unusual hemorrhagic presentation of this typically benign entity is extremely rare and is thought to be intra-tumoral bleeding in this case, since subarachnoid hemorrhage was absent.
  • [MeSH-major] Astrocytoma / blood supply. Astrocytoma / complications. Brain Neoplasms / blood supply. Brain Neoplasms / complications. Cerebral Hemorrhage / etiology. Hematoma / etiology

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  • [CommentIn] J Neurooncol. 2006 Mar;77(1):105-6 [16292492.001]
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  • (PMID = 15690134.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Kuwashiro T, Toyoda K, Otsubo R, Ishibashi-Ueda H, Tagusari O, Minematsu K: Cardiac papillary fibroelastoma as a cause of embolic stroke: ultrasound and histopathological characteristics. Intern Med; 2009;48(1):77-80
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  • Although a cardiac papillary fibroelastoma is a benign cardiac tumor, it can cause severe embolic complications.
  • A 51-year-old man presented with an ischemic stroke in the right middle cerebral artery territory.
  • Transesophageal echocardiography revealed a small mobile tumor on the mitral valve as the only detectable source of emboli to the brain.
  • On histology, the tumor was diagnosed as a papillary fibroelastoma.
  • In this paper, the detailed characteristics of the tumor on ultrasound and histopathology are documented.

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  • (PMID = 19122362.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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22. Koch HJ, Roeber S, Zimmermann UW, Schäfer C, Villarrubia V, Kuchelmeister K, Schachenmayr W, Bogdahn U, Steinbrecher A: [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle]. Wien Med Wochenschr; 2005 Aug;155(15-16):360-4
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  • [Title] [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
  • Meningeal melanocytoma refers to the uncommon clinical appearance of a generally benign tumour deriving from leptomeningeal melanocytes.
  • Meningeal spread of this tumour is very rarely observed.
  • This tumor did not respond to a combined radiochemotherapy including oral temozolomide, and the patient died 5 months after starting treatment for this relapse.
  • [MeSH-major] Cerebellopontine Angle. Melanocytes / pathology. Melanoma. Meningeal Neoplasms. Meninges. Neoplasm Seeding
  • [MeSH-minor] Administration, Oral. Adult. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / therapeutic use. Arachnoid. Cerebellar Diseases / diagnosis. Cerebellar Neoplasms / diagnosis. Combined Modality Therapy. Dacarbazine / analogs & derivatives. Dacarbazine / therapeutic use. Diagnosis, Differential. Disease Progression. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Pia Mater. Radiotherapy Dosage. Time Factors

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  • (PMID = 16160923.001).
  • [ISSN] 0043-5341
  • [Journal-full-title] Wiener medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Wien Med Wochenschr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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23. Schiopu C, Flangea C, Capitan F, Serb A, Vukelić Z, Kalanj-Bognar S, Sisu E, Przybylski M, Zamfir AD: Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry. Anal Bioanal Chem; 2009 Dec;395(8):2465-77
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  • We report here on a preliminary investigation of ganglioside composition and structure in human hemangioma, a benign tumor in the frontal cortex (HFC) in comparison to normal frontal cortex (NFC) tissue using for the first time advanced mass spectrometric methods based on fully automated chip-nanoelectrospray (nanoESI) high-capacity ion trap (HCT) and collision-induced dissociation (CID).
  • This aspect suggests that these O-acetylated structures could be associated with cerebral tumors having reduced malignancy grade.
  • Fragmentation analysis by CID in MS(2) mode using as precursors the ions corresponding to GT1 (d18:1/20:0) and GD1 (d18:1/20:0) provided data corroborating for the first time the presence of the common GT1a and GT1b isomers and the incidence of unusual GT1c and GT1d glycoforms in brain hemangioma tumor.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Brain Neoplasms / metabolism. Gangliosides / chemistry. Gangliosides / metabolism. Hemangioma / metabolism. Spectrometry, Mass, Electrospray Ionization / methods. Tandem Mass Spectrometry / methods
  • [MeSH-minor] Adult. Brain / metabolism. Case-Control Studies. Cerebral Cortex / metabolism. Frontal Lobe / metabolism. Humans. Isomerism. Male. N-Acetylneuraminic Acid / analysis. Nanotechnology

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  • (PMID = 19841910.001).
  • [ISSN] 1618-2650
  • [Journal-full-title] Analytical and bioanalytical chemistry
  • [ISO-abbreviation] Anal Bioanal Chem
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Gangliosides; GZP2782OP0 / N-Acetylneuraminic Acid
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24. Zhi L, Bing L, Yang L, Bo-ning L, Quan H: Cystic papillary meningioma with subarachnoid dissemination: a case report and review of the literature. Pathol Res Pract; 2009;205(8):582-7
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  • Meningiomas usually present as benign tumors corresponding to WHO grade I.
  • The tumor exhibits a marked peritumoral cyst, with contrast enhancement on magnetic resonance imaging (MRI) in accordance with type 2 of Zee's classification of cystic meningioma.
  • Histologically, the tumor displays a classical perivascular pseudopapillary pattern with focal necrosis and subarachnoid space dissemination.
  • Tumor cells are diffusely positive for epithelial membrane antigen (EMA) and vimentin, but lack immunoreactivity for cytokeratin (CK) and glial fibrillary acidic protein (GFAP).
  • MIB-1 labeling is high, accounting for 5% of tumor focally.
  • In addition, the biological behavior and the clinical outcome of this tumor are also discussed.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Cysts / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Female. Humans. Magnetic Resonance Imaging. Mucin-1 / metabolism. Neoplasm Staging. Treatment Outcome. Vimentin / metabolism. Young Adult

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  • (PMID = 19307065.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucin-1; 0 / Vimentin
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25. Berne JP, Bouchot O, Jazayeri S, Tatou E, Gomez-Bielfeld MC, Martin L, Brenot R, David M: [Cardiac papillary fibroelastoma, a rare valvular source of cerebral embolism: report of two cases]. Ann Cardiol Angeiol (Paris); 2009 Feb;58(1):61-3
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  • [Title] [Cardiac papillary fibroelastoma, a rare valvular source of cerebral embolism: report of two cases].
  • Cardiac papillary fibroelastomas are very rare and benign tumors, usually involving heart valves.
  • The only curative treatment consists of the excision of the tumor under cardiopulmonary bypass.
  • We report the cases of two patients suffering from acute cerebral embolism.

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  • (PMID = 18980749.001).
  • [ISSN] 1768-3181
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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26. Zhang H, Rödiger LA, Shen T, Miao J, Oudkerk M: Preoperative subtyping of meningiomas by perfusion MR imaging. Neuroradiology; 2008 Oct;50(10):835-40
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  • INTRODUCTION: This paper aims to evaluate the value of perfusion magnetic resonance (MR) imaging in the preoperative subtyping of meningiomas by analyzing the relative cerebral blood volume (rCBV) of three benign subtypes and anaplastic meningiomas separately.
  • The maximal rCBV (compared with contralateral normal white matter) in both tumoral parenchyma and peritumoral edema of each tumor was measured.

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  • (PMID = 18542938.001).
  • [ISSN] 0028-3940
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Journal Article
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27. Hsu TR, Wong TT, Chang FC, Ho DM, Tang RB, Thien PF, Chang KP: Responsiveness of progressive optic pathway tumors to cisplatin-based chemotherapy in children. Childs Nerv Syst; 2008 Dec;24(12):1457-61
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  • BACKGROUND: Though the pathology of optic pathway tumor is mostly pilocytic astrocytoma, the benign tumor behaves like malignant tumor because total resection is not feasible.
  • We evaluate the responsiveness of optic pathway tumor to cisplatin-based chemotherapy.
  • The toxicity of the cisplatin-based chemotherapy showed mild bone marrow suppression in 13 patients (81.3%), infection in nine patients (56.3%), gastrointestinal discomfort in seven patients (43.8%), renal insufficiency in two patient (12.5%), cerebral salt wasting syndrome with hyponatremia in one patient (6.25%) and high pitch hearing loss in two patients (12.5%).

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  • (PMID = 18769928.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 5V9KLZ54CY / Vinblastine; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
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28. Ceyssens S, Van Laere K, de Groot T, Goffin J, Bormans G, Mortelmans L: [11C]methionine PET, histopathology, and survival in primary brain tumors and recurrence. AJNR Am J Neuroradiol; 2006 Aug;27(7):1432-7
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  • METHODS: Cerebral uptake of MET was determined in 52 patients: in 26 patients for primary staging (group A) and 26 patients with suspected brain tumor recurrence/progression after therapy (group B).
  • Semiquantitative methionine uptake indices (UI) defined by the tumor (maximum)-to-background ratio was correlated with tumor grade and final outcome.
  • Although a weak linear correlation between MET uptake and grading was observed (R = 0.38, P = .028), analysis of variance showed no significant differences in MET UI between tumor grades for either group A or B.
  • Benign and grade I lesions showed significant difference in MET uptake in comparison with higher grade lesions (P = .006).
  • [MeSH-major] Brain Neoplasms / radionuclide imaging. Carbon Radioisotopes. Glioma / radionuclide imaging. Methionine. Neoplasm Recurrence, Local / pathology. Positron-Emission Tomography / methods. Radiopharmaceuticals
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / pathology. Astrocytoma / radionuclide imaging. Astrocytoma / therapy. Brain / metabolism. Child. Child, Preschool. Disease Progression. Female. Forecasting. Humans. Male. Middle Aged. Neoplasm Staging. Oligodendroglioma / pathology. Oligodendroglioma / radionuclide imaging. Oligodendroglioma / therapy. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 16908552.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carbon Radioisotopes; 0 / Radiopharmaceuticals; AE28F7PNPL / Methionine
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29. Saint-Blancard P, Goasguen O, Kossowski M, Dulou R: [A rare primary tumor of the cerebellopontine angle: melanotic schwannoma, a pigmented tumor with unpredictable prognosis]. Rev Med Interne; 2008 Jul;29(7):587-90
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  • [Title] [A rare primary tumor of the cerebellopontine angle: melanotic schwannoma, a pigmented tumor with unpredictable prognosis].
  • Schwannomas are common ubiquitous benign tumours of the nervous sheaths.
  • We report a case of melanotic schwannoma of the cerebellopontine angle in a 52-year-old man with a slowly progressive cerebellar syndrome since 1978, who presented with a posterior cerebral fossa bleeding.

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  • (PMID = 18276040.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Melanins
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30. Prayson RA: Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation. Ann Diagn Pathol; 2009 Feb;13(1):36-40
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  • [Title] Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation.
  • Cases of cerebral neuroblastoma or supratentorial primitive neuroectodermal tumor with malignant gliomatous components are relatively uncommon.
  • This is a case report of a lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation occurring in a 48-year-old woman.
  • These cells were arranged against a benign lipomatous background.
  • The glioblastomatous component of the tumor demonstrated glial fibrillary acidic protein immunoreactivity.

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  • (PMID = 19118780.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Synaptophysin
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31. Ortega-Martínez M, Cabezudo-Artero JM, Fernández-Portales I, Pimentel JJ, Gómez de Tejada R: Diffuse leptomeningeal seeding from benign choroid plexus papilloma. Acta Neurochir (Wien); 2007 Dec;149(12):1229-36; discussion 1236-7
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  • [Title] Diffuse leptomeningeal seeding from benign choroid plexus papilloma.
  • Although they are histologically benign, local recurrences may occasionally occur, but leptomeningeal dissemination is exceptional.
  • Neither the initial tumour nor the recurrence showed malignant histological features.
  • We review the literature concerning leptomeningeal dissemination of benign choroid plexus papillomas.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Fourth Ventricle / surgery. Meningeal Neoplasms / secondary. Neoplasm Seeding. Papilloma, Choroid Plexus / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biopsy. Disease Progression. Fatal Outcome. Female. Humans. Ki-67 Antigen / analysis. Laminectomy. Magnetic Resonance Imaging. Meninges / pathology. Reoperation. S100 Proteins / analysis

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  • (PMID = 17924056.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / S100 Proteins
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32. Houtteville JP: [Cavernomas of the central nervous system. Historical data and changing ideas]. Neurochirurgie; 2007 Jun;53(2-3 Pt 2):117-21
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  • Since the advent of modern neuroimaging (MRI) cerebral cavernomas are usually diagnosed "in vivo".
  • 1) nosologically, cerebral cavernomas belong to the group of cerebral vascular hamartomas which can be associated between themselves ("mixed" lesions);.
  • 4) immunocytochemical studies (PCNA) show that cavernomas should be considered more as a benign vascular tumor than as a malformation;.

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  • (PMID = 17499816.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 14
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33. Kobayashi H, Ishii N, Murata J, Saito H, Kubota KC, Nagashima K, Iwasaki Y: Cystic meningioangiomatosis. Pediatr Neurosurg; 2006;42(5):320-4
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  • A case of cerebral meningioangiomatosis with rare cyst formation is reported.
  • Neuroradiological studies showed an abnormal cystic mass with calcification in the left frontal lobe of the cerebrum.
  • The tumor was located in the leptomeninges and cerebral cortex.
  • It is important to distinguish meningioangiomatosis from other possible cortical lesions and epileptic foci should be carefully considered before resection, because it is a benign and surgically manageable cause of seizures.
  • [MeSH-major] Angiomatosis / surgery. Brain Diseases / surgery. Cerebral Cortex / surgery. Meninges / surgery

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  • [Copyright] Copyright 2006 S. Karger AG, Basel.
  • (PMID = 16902347.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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34. Balamurali G, du Plessis DG, Wengoy M, Bryan N, Herwadkar A, Richardson PL: Thorotrast-induced primary cerebral angiosarcoma: case report. Neurosurgery; 2009 Jul;65(1):E210-1; discussion E211
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  • [Title] Thorotrast-induced primary cerebral angiosarcoma: case report.
  • OBJECTIVE: Thorotrast was used as a contrast medium in clinical practice until the 1960s for outlining cerebral abscess cavities and ventricular cavities, and for angiography.
  • CLINICAL PRESENTATION: The patient presented with a progressive left-sided weakness 62 years after initial surgery for a right parietal cerebral abscess, which included the instillation of Thorotrast into the abscess cavity.
  • Computed tomography showed a right parietal tumor.
  • INTERVENTION: An explorative craniotomy showed an intrinsic, infiltrating, very vascular tumor with surrounding calcification.
  • The tumor appeared to arise from a benign cavernous vasoformative lesion intimately associated with a Thorotrast-type granuloma.
  • CONCLUSION: The histology, confirmation of radioactivity of the material obtained from within the tumor, and latency period of presentation provide compelling support for tumor induction by the Thorotrast.
  • Primary lesions of the central nervous system associated with Thorotrast are very rarely reported, despite its extensive use in cerebral angiography and management of brain abscess between 1930 and 1960.
  • [MeSH-minor] Aged. Cerebral Angiography. Cerebral Cortex / pathology. Cerebral Cortex / surgery. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 19574803.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 9XA7X17UQC / Thorium Dioxide
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35. Josan V, Smith P, Kornberg A, Rickert C, Maixner W: Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report. J Neurosurg; 2007 Jun;106(6 Suppl):509-12
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  • [Title] Development of a pilocytic astrocytoma in a dysembryoplastic neuroepithelial tumor. Case report.
  • Dysembryoplastic neuroepithelial tumors (DNETs) are benign supratentorial tumors based in the cerebral cortex.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Cerebral Cortex. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Neuroectodermal Tumors, Primitive / diagnosis


36. Yoshida S, Masuda H, Ishii C, Saito K, Kawakami S, Kihara K: Initial experience of functional imaging of upper urinary tract neoplasm by diffusion-weighted magnetic resonance imaging. Int J Urol; 2008 Feb;15(2):140-3
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  • [Title] Initial experience of functional imaging of upper urinary tract neoplasm by diffusion-weighted magnetic resonance imaging.
  • OBJECTIVES: Diffusion-weighted (DW) magnetic resonance imaging (MRI) provides functional information widely used in the diagnosis of acute cerebral stroke.
  • The last patient was confirmed as experiencing benign stenosis.
  • The apparent diffusion coefficient (ADC) values of renal parenchyma, dilated collecting system, and tumor were calculated.
  • The case of benign stenosis had negative DW MRI.
  • The median (range) ADC value of the tumor (0.803 [0.412-0.958] x 10(-3) mm(2)/s) was significantly lower than those of the dilated collecting system (2.19 [1.42-2.40] x 10(-3)) and renal parenchyma (1.28 [0.922-1.45] x 10(-3), respectively (P < 0.01 and P < 0.01).

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  • (PMID = 18269448.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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37. Sawada K, Maehara T, Inaji M, Toriyama H, Okada T, Nariai T, Aoyagi M, Doi M, Ohno K: [Case of ruptured multiple cerebral aneurysms associated with primary aldosteronism]. No Shinkei Geka; 2010 Apr;38(4):347-51
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  • [Title] [Case of ruptured multiple cerebral aneurysms associated with primary aldosteronism].
  • Primary aldosteronism (PA) has been recognized as a relatively benign form of hypertension associated with a low incidence of vascular complications.
  • Cerebral angiography showed multiple small aneurysms.
  • The initial intervention was aneurysm clipping for a ruptured aneurysm at the bifurcation of the right middle cerebral artery.
  • She was diagnosed with PA on the basis of elevated plasma aldosterone, suppressed plasma rennin, and a right adrenal tumor detected by abdominal CT scanning.

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  • (PMID = 20387576.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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38. Rushing EJ, Cooper PB, Quezado M, Begnami M, Crespo A, Smirniotopoulos JG, Ecklund J, Olsen C, Santi M: Subependymoma revisited: clinicopathological evaluation of 83 cases. J Neurooncol; 2007 Dec;85(3):297-305
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  • To date, a large clinicopathologic study of these benign neoplasms treated with modern neurosurgical techniques has not been reported.
  • Eighteen-percent (15/83) of subependymomas exhibited a mixed histologic pattern; that is, subependymoma together with another glial tumor.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Ependymoma / pathology. Glioma, Subependymal / pathology. Infratentorial Neoplasms / pathology. Mixed Tumor, Malignant / pathology

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  • (PMID = 17569000.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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39. Schmalisch K, Beschorner R, Psaras T, Honegger J: Postoperative intracranial seeding of craniopharyngiomas--report of three cases and review of the literature. Acta Neurochir (Wien); 2010 Feb;152(2):313-9; discussion 319
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  • Postoperative MRI showed no evidence of residual tumor.
  • Two years later, MRI revealed a local recurrence and in addition a separated cystic tumor on the right side adjacent to the middle cerebral artery consistent with seeding along the surgical route.
  • On histopathological examination, both, the local recurrent tumor and the distant deposit turned out to be adamantinomatous craniopharyngiomas.
  • This deposit in the operative pathway was found to be an adamantinomatous craniopharyngioma, as was the initial tumor.
  • The recent control MRT revealed a right parietal intracranial tumor with peripheral contrast enhancement, which was located distant to the former craniotomy.
  • The tumor was removed and histopathological examination revealed an adamantinomatous craniopharyngioma in accordance with the initial tumor.
  • CONCLUSION: Although craniopharyngiomas exhibit a benign histopathological pattern, cerebrospinal fluid seeding along the surgical route or along the CSF pathways has been observed.
  • Ectopic recurrence of craniopharyngioma suggests that meticulous protection of the whole surgical field and careful handling of the tumor during the operation are required.
  • [MeSH-major] Brain Neoplasms / secondary. Craniopharyngioma / secondary. Neoplasm Metastasis / pathology. Neoplasm Seeding. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Craniotomy. Female. Frontal Bone / pathology. Frontal Bone / surgery. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Parietal Bone / pathology. Parietal Bone / surgery. Reoperation. Treatment Outcome

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  • (PMID = 19859655.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 31
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40. Koçak H, Ozyazicioğlu A, Gündoğdu C, Sevimli S: Cardiac hemangioma complicated with cerebral and coronary embolization. Heart Vessels; 2005 Nov;20(6):296-7
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  • [Title] Cardiac hemangioma complicated with cerebral and coronary embolization.
  • Cardiac hemangiomas are rare, benign vascular tumors of the heart.
  • Histopathological examination revealed that the tumor was a hemangioma.


41. Sentürk S, Oğuz KK, Cila A: Dynamic contrast-enhanced susceptibility-weighted perfusion imaging of intracranial tumors: a study using a 3T MR scanner. Diagn Interv Radiol; 2009 Mar;15(1):3-12
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  • PURPOSE: To determine whether there are statistically significant differences in cerebral blood volume (CBV) and cerebral blood flow (CBF) of brain tumors of different histopathologic types including primary and secondary benign and malignant lesions.
  • To determine whether these measurements relate to tumor grade.
  • The lesions were evaluated by measurements of relative cerebral blood volume (rCBV) and relative cerebral blood flow (rCBF).
  • The Mann-Whitney U test was used to compare rCBV and rCBF measurements of tumor groups -- 13 low-grade and 13 high-grade neuroepithelial (NE) tumors, five metastases, 10 meningiomas, and four others.
  • CONCLUSION: CBV and CBF measurements provided by 3T perfusion MRI can help to predict NE tumor grading preoperatively, and differentiate between primary brain tumors and metastases.

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  • (PMID = 19263367.001).
  • [ISSN] 1305-3612
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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42. Bakoyiannis KC, Georgopoulos SE, Klonaris CN, Tsekouras NS, Felekouras ES, Pikoulis EA, Griniatsos JE, Papalambros EL, Bastounis EA: Surgical treatment of carotid body tumors without embolization. Int Angiol; 2006 Mar;25(1):40-5
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  • AIM: Carotid body (CB) paragangliomas are rare neoplasms, usually benign.
  • Twelve tumors were surgically resected and no patient underwent preoperative selective embolism of his tumor.
  • No stroke or any other cerebral event was observed.
  • One patient, with a grade III tumor, had an injury of the internal carotid artery that was repaired with a vein patch.
  • Preoperative embolism of the tumor does not need to be a routine procedure.
  • [MeSH-major] Carotid Body Tumor / surgery. Endarterectomy, Carotid
  • [MeSH-minor] Adult. Aged. Angioplasty. Female. Humans. Male. Medical Records. Middle Aged. Neoplasm Staging. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 16520723.001).
  • [ISSN] 0392-9590
  • [Journal-full-title] International angiology : a journal of the International Union of Angiology
  • [ISO-abbreviation] Int Angiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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43. Fraser MM, Bayazitov IT, Zakharenko SS, Baker SJ: Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities. Neuroscience; 2008 Jan 24;151(2):476-88
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  • The tumor-suppressor phosphatase with tensin homology (PTEN) is the central negative regulator of the PI3K pathway.
  • Germline PTEN mutations result in cancer predisposition, macrocephaly and benign hamartomas in many tissues, including Lhermitte-Duclos disease, a cerebellar growth disorder.
  • Electron microscopic evaluation revealed enlarged abnormal synaptic structures in the cerebral cortex and cerebellum.

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  • (PMID = 18082964.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA096832-01A10004; United States / NCI NIH HHS / CA / CA096832; United States / NINDS NIH HHS / NS / R01 NS044172; United States / NINDS NIH HHS / NS / NS044172; United States / NCI NIH HHS / CA / P01 CA096832-05; United States / NCI NIH HHS / CA / P01 CA096832; United States / NCI NIH HHS / CA / CA096832-05; United States / NCI NIH HHS / CA / P01 CA096832-01A10004
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; EC 3.1.3.67 / PTEN Phosphohydrolase
  • [Other-IDs] NLM/ NIHMS39023; NLM/ PMC2278004
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44. Laxton AW, Shannon P, Nag S, Farb RI, Bernstein M: Rapid expansion of a previously asymptomatic subependymoma. Case report. J Neurosurg; 2005 Dec;103(6):1084-7
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  • One month after his initial presentation, he was admitted to the hospital with significant tumor expansion and clinical deterioration.
  • Histopathological analysis of this tumor showed central necrosis with associated edema in an otherwise typical and benign-appearing subependymoma.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Glioma, Subependymal / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 16381197.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Molloy ES, Hajj-Ali RA: Primary angiitis of the central nervous system. Curr Treat Options Neurol; 2007 May;9(3):169-75
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  • Primary angiitis of the central nervous system (PACNS) is a rare disorder that must be differentiated from secondary CNS vasculitides, reversible cerebral vasoconstriction syndromes, and other vascular disorders.
  • PACNS has been considered to have three major subsets, as defined by clinical, laboratory, angiographic, and pathologic findings: granulomatous angiitis of the central nervous system (GACNS), benign angiopathy of the central nervous system (BACNS), and atypical PACNS.
  • Approximately 5% of cases may present as a tumor-like mass lesion.
  • This reflects the fact that BACNS is now more correctly considered as a reversible cerebral vasoconstriction syndrome (RCVS) and not as a true vasculitis.

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  • (PMID = 17445494.001).
  • [ISSN] 1092-8480
  • [Journal-full-title] Current treatment options in neurology
  • [ISO-abbreviation] Curr Treat Options Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Trejos H, Caceres A, Segura JL: Monstrous craniopharyngioma. Case presentations and term proposal. Childs Nerv Syst; 2005 Dec;21(12):1049-53; discussion 1054-5
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  • INTRODUCTION: Craniopharyngiomas (CF) are benign tumors, which can be cured by total resection; however, this is not always possible to achieve, thus leading to tumor recurrence.
  • [MeSH-minor] Cerebral Angiography / methods. Child. Child, Preschool. Female. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 15759158.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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47. Sarkar R, Yong WH, Lazareff JA: A case report of intraventricular gliofibroma. Pediatr Neurosurg; 2009;45(3):210-3
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  • Gliofibroma is a rare tumor with biphasic morphology.
  • CT and MRI showed the presence of a large heterogeneous, nonenhancing tumor filling the atria and bodies of the lateral ventricles with caudal extension into the third ventricle.
  • Recent MRI showed stable appearance of the tumor and clinically the patient is neurologically intact with normal cognitive development.
  • As evident from our case report, we recommend a conservative treatment approach for gliofibroma with benign histology.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fibroma / pathology. Glioma / pathology

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19521134.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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48. Ginat DT, Mangla R, Yeaney G, Wang HZ: Correlation of diffusion and perfusion MRI with Ki-67 in high-grade meningiomas. AJR Am J Roentgenol; 2010 Dec;195(6):1391-5
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  • OBJECTIVE: Atypical and anaplastic meningiomas have a greater likelihood of recurrence than benign meningiomas.
  • The purpose of this study was to determine the correlation between Ki-67 and regional cerebral blood volume (rCBV) and between Ki-67 and apparent diffusion coefficient (ADC) in atypical and anaplastic meningiomas.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Blood Volume. Cerebrovascular Circulation. Diffusion Magnetic Resonance Imaging. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Linear Models. Male. Middle Aged. Retrospective Studies

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  • (PMID = 21098200.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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49. Sura P, Srebro Z: Cerebral pathology in immunodeficient gnotobiotic laboratory mice. Folia Biol (Krakow); 2005;53(3-4):205-8
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  • [Title] Cerebral pathology in immunodeficient gnotobiotic laboratory mice.
  • Gnotobiotic autoimmunity prone, antigen presentation, T lymphocyte receptor gene knockout mice show cerebral pathology in the form of meningitis, venous blood statis with subarachnoid hemorrhages and massive hemosiderin deposits.
  • Only in the latter strain was a strong pineal hypertrophy in the form of a benign tumor present in ca.
  • [MeSH-major] Cerebrum / pathology

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  • (PMID = 19058545.001).
  • [ISSN] 0015-5497
  • [Journal-full-title] Folia biologica
  • [ISO-abbreviation] Folia Biol. (Krakow)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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50. Bouaziz M, Mansour A, Feknous S, Yassi F, Smati S, Belhouchet S, Lankar A: [Central neurocytoma: case report]. Neurochirurgie; 2009 Dec;55(6):581-4
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  • It is a benign tumor of the lateral ventricles of the brain with neuronal differentiation.
  • [MeSH-major] Brain Neoplasms / surgery. Cerebral Ventricle Neoplasms / surgery. Neurocytoma / surgery

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  • (PMID = 19447451.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Chromatin; 0 / Synaptophysin
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51. Asioli S, Senetta R, Maldi E, D'Ambrosio E, Satolli MA, Bussolati G, Cassoni P: "Benign" metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lung. Virchows Arch; 2007 May;450(5):591-4
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  • [Title] "Benign" metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lung.
  • Lung "metastases" of benign meningiomas are rarely described events of biological and clinical interest.
  • Anamnesis revealed that the patient underwent a surgical resection of cerebral meningioma 12 years before.
  • The morphological and immunohistochemical features of this lesion, together with the similarity with the original cerebral tumour and its indolent evolution, led to a final diagnosis of "benign" meningioma metastatic to the lung.
  • They represent a typical example of "benign" tumours that may implant to the lung similar to other tumours, definitely considered benign but reported to rarely present unusual secondary localization.
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Female. Humans. Neoplasm Metastasis / pathology. Tomography, X-Ray Computed

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  • (PMID = 17431673.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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52. Pratheesh R, Moorthy RK, Singh R, Rajshekhar V: Choroid plexus papilloma presenting as a non-contrast-enhancing fourth ventricular mass in a child. Neurol India; 2009 Jul-Aug;57(4):486-8
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  • Choroid plexus papilloma (CPP) is a rare benign tumor of the central nervous system with a propensity for location within the lateral ventricle in children.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Fourth Ventricle / pathology. Papilloma, Choroid Plexus / diagnosis
  • [MeSH-minor] Adolescent. Cerebral Ventriculography / methods. Female. Humans. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed

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  • (PMID = 19770555.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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53. Benedict WJ Jr, Brown HG, Sivarajan G, Prabhu VC: Intraventricular schwannoma in a 15-year-old adolescent: a case report. Childs Nerv Syst; 2008 Apr;24(4):529-32
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  • INTRODUCTION: Schwannomas are benign tumors that originate from the myelin-forming Schwann cells of peripheral nerves or at the Obersteiner-Redlich zone of the vestibular division of the eighth cranial nerve.
  • DISCUSSION: This case report illustrates a right occipital horn schwannoma in a 15-year-old adolescent boy who was successfully treated with surgical resection and discusses the possible origins of the tumor in this unique location.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Cerebral Ventricle Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery

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  • (PMID = 18175126.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 13
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54. Nayar VV, DeMonte F, Yoshor D, Blacklock JB, Sawaya R: Surgical approaches to meningiomas of the lateral ventricles. Clin Neurol Neurosurg; 2010 Jun;112(5):400-5
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  • In 9 of 13 cases, the tumor occurred in the left lateral ventricle.
  • Pathology was benign in 12 of 13 cases; atypical features were identified in one case.
  • Tumor location, extension, and laterality drive the selection algorithm for these approaches.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Cerebral Ventricle Neoplasms / surgery. Lateral Ventricles / pathology. Lateral Ventricles / surgery. Meningioma / pathology. Meningioma / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aphasia / epidemiology. Aphasia / etiology. Cerebral Angiography / methods. Female. Humans. Male. Middle Aged. Perceptual Disorders / epidemiology. Perceptual Disorders / etiology. Postoperative Complications. Preoperative Care. Recovery of Function. Stereotaxic Techniques. Surgery, Computer-Assisted. Treatment Outcome. Young Adult

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20197209.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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55. Zhang H, Rödiger LA, Shen T, Miao J, Oudkerk M: Perfusion MR imaging for differentiation of benign and malignant meningiomas. Neuroradiology; 2008 Jun;50(6):525-30
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  • [Title] Perfusion MR imaging for differentiation of benign and malignant meningiomas.
  • INTRODUCTION: Our purpose was to determine whether perfusion MR imaging can be used to differentiate benign and malignant meningiomas on the basis of the differences in perfusion of tumor parenchyma and/or peritumoral edema.
  • METHODS: A total of 33 patients with preoperative meningiomas (25 benign and 8 malignant) underwent conventional and dynamic susceptibility contrast perfusion MR imaging.
  • Maximal relative cerebral blood volume (rCBV) and the corresponding relative mean time to enhance (rMTE) (relative to the contralateral normal white matter) in both tumor parenchyma and peritumoral edema were measured.
  • The independent samples t-test was used to determine whether there was a statistically significant difference in the mean rCBV and rMTE ratios between benign and malignant meningiomas.
  • RESULTS: The mean maximal rCBV values of benign and malignant meningiomas were 7.16+/-4.08 (mean+/-SD) and 5.89+/-3.86, respectively, in the parenchyma, and 1.05+/-0.96 and 3.82+/-1.39, respectively, in the peritumoral edema.
  • The differences in rCBV and rMTE values between benign and malignant meningiomas were not statistically significant (P>0.05) in the parenchyma, but both were statistically significant (P<0.05) in the peritumoral edema.
  • Measurement of maximal rCBV and corresponding rMTE values in the peritumoral edema is useful in the preoperative differentiation between benign and malignant meningiomas.

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  • (PMID = 18379768.001).
  • [ISSN] 0028-3940
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
  • [Other-IDs] NLM/ PMC2440923
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56. Liu AK, Bagrosky B, Fenton LZ, Gaspar LE, Handler MH, McNatt SA, Foreman NK: Vascular abnormalities in pediatric craniopharyngioma patients treated with radiation therapy. Pediatr Blood Cancer; 2009 Feb;52(2):227-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Craniopharyngioma is a benign brain tumor that can be treated with some combination of surgery, intracystic chemotherapy and radiation therapy.
  • One had bilateral temporal cavernomas, one had moyamoya syndrome, one had an aneurysm of the internal carotid artery and three children had decreases in the caliber of the carotid or cerebral arteries, but were asymptomatic.

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18937328.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 11056-06-7 / Bleomycin
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57. Ulivieri S, Oliveri G: Intraventricular neurocytoma: case report. Pathologica; 2007 Oct;99(5):309-12
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  • Intraventricular neurocytoma is a rare, usually benign tumour of neuronal differentiation, recently recognized as a clinico-pathological entity in comparison to the other intraventricular tumours.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Neurocytoma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Corpus Callosum / pathology. Craniotomy. Humans. Male. Synaptophysin / analysis

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  • (PMID = 18354953.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Synaptophysin
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58. Dapena-Sevilla I, Drake-Rodríguez P, Gutiérrez-Ortiz C, Bolívar G, Castejón M, Teus-Guezala MA: [Band atrophy of the optic disc secondary to ventricular subependymoma compression]. Arch Soc Esp Oftalmol; 2007 Sep;82(9):567-9
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  • Craniotomy and tumor resection were performed.
  • Subependymomas are infrequent and benign tumors that are typically associated with the ventricular system.
  • [MeSH-major] Cerebral Ventricle Neoplasms / complications. Glioma, Subependymal / complications. Optic Atrophy / etiology

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  • (PMID = 17846949.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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59. Wang F, Qiao G, Li X, Gui Q: A dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus in a 57-year-old woman: case report. Neurosurgery; 2007 Aug;61(2):E420; discussion E420
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  • [Title] A dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus in a 57-year-old woman: case report.
  • DNTs may also arise outside of the cerebral cortex.
  • During a 7-year follow-up period, the tumor did not recur.
  • CONCLUSION: Unlike diffuse gliomas, such as oligodendrogliomas and central neurocytomas, DNTs are benign lesions with a favorable prognosis after surgical resection.

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  • (PMID = 17762726.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Tsutsumi S, Abe Y, Yasumoto Y, Shiono S, Ito M: Metastatic skull base tumor from thymic carcinoma mimicking Tolosa-Hunt syndrome. Neurol Med Chir (Tokyo); 2010;50(6):499-502
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  • [Title] Metastatic skull base tumor from thymic carcinoma mimicking Tolosa-Hunt syndrome.
  • Magnetic resonance imaging confirmed a broad-based, intensely enhanced extraaxial tumor of 4x4x4 cm diameter with dural tail sign.
  • Cerebral angiography demonstrated insignificant blood supply both from the internal carotid and middle meningeal arteries.
  • Nearly total tumor resection was achieved via orbitofrontotemporal craniotomy.
  • Intraoperative findings revealed the extraaxial tumor with broad attachment to the dura mater and invasion to the optic and oculomotor nerves.
  • Histological examination revealed hypercellular tumor with significant cell atypism, mitotic activity, and focal necrosis.
  • Systemic examination performed postoperatively revealed a thymic tumor without additional remote lesions.
  • The final diagnosis was metastatic brain tumor from thymic carcinoma.
  • Rapid progression of neurological impairment inconsistent with a benign extraaxial tumor needs prompt surgical intervention.

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  • (PMID = 20587979.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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61. Cheng CH, Liu CL, Chen CC, Lin SZ, Cho DY: Single-port endoscopic removal of intraventricular central neurocytoma. J Clin Neurosci; 2010 Nov;17(11):1417-20
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  • Central neurocytoma is a rare benign intraventricular tumor which occurs in young adults.
  • Craniotomy with tumor removal is associated with relatively high rates of morbidity and mortality.
  • To improve the efficiency of endoscopic surgery for removal of this tumor, we used a polypropylene tube combined with a working channel endoscope.
  • The tumor was almost totally removed.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Endoscopy / methods. Neurocytoma / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Cerebral Ventricles / surgery. Female. Humans. Magnetic Resonance Imaging. Young Adult

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20655233.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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62. Deb P, Sarkar C, Garg A, Singh VP, Kale SS, Sharma MC: Intracranial gliofibroma mimicking a meningioma: a case report and review of literature. Clin Neurol Neurosurg; 2006 Feb;108(2):178-86
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  • Gliofibromas are rare glio-mesenchymal tumors composed of astrocytic and benign mesenchymal components, which commonly occur in the first two decades of life.
  • Post-operatively, the residual tumor regrew to a size similar to the initial mass (4 cm x 3.6 cm x 3.5 cm), within one and a half years after the first surgery.
  • The histopathology of the tumor was similar on both occasions.
  • Although a poor prognosis has been characteristically noted in gliofibromas with high-grade glial component, but the present case had recurrence despite being of low-grade, thus highlighting the uncertain behaviour of this rare tumor.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Fibroma / diagnosis. Glioma / diagnosis. Meningioma / diagnosis. Neoplasm Recurrence, Local / diagnosis. Third Ventricle

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  • (PMID = 16412839.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 24
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63. Rim NJ, Kim HS, Kim SY: A "benign" sphenoid ridge meningioma manifesting as a subarachnoid hemorrhage associated with tumor invasion into the middle cerebral artery. Korean J Radiol; 2008 Jul;9 Suppl:S10-3
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  • [Title] A "benign" sphenoid ridge meningioma manifesting as a subarachnoid hemorrhage associated with tumor invasion into the middle cerebral artery.
  • We present a case of sphenoid ridge meningotheliomatous meningioma manifesting as an SAH without pathologically atypical or malignant features, due to direct tumor invasion into the middle cerebral artery.
  • [MeSH-major] Meningeal Neoplasms / complications. Meningioma / complications. Middle Cerebral Artery / pathology. Skull Neoplasms / complications. Sphenoid Bone. Subarachnoid Hemorrhage / etiology
  • [MeSH-minor] Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • [Cites] Acta Neurochir (Wien). 2000;142(2):165-8 [10795890.001]
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  • (PMID = 18607117.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627185
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64. Yoshikawa G, Kawamoto S, Yakou K, Tsutsumi K: Massive intracranial hemorrhage associated with pleomorphic xanthoastrocytoma--case report. Neurol Med Chir (Tokyo); 2010;50(3):220-3
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  • Cerebral angiography on admission revealed occlusion of the P(2) segment of the left posterior cerebral artery (PCA) and extravasation of contrast medium during the procedure.
  • Presumably the bleeding was caused by the rupture of a pseudoaneurysm secondary to leptomeningeal involvement of this typically benign tumor.
  • [MeSH-minor] Cerebral Angiography. Female. Humans. Middle Aged. Posterior Cerebral Artery. Severity of Illness Index. Temporal Lobe / blood supply. Temporal Lobe / pathology. Temporal Lobe / surgery. Treatment Outcome

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  • (PMID = 20339272.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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65. Akamatsu Y, Utsunomiya A, Suzuki S, Endo T, Suzuki I, Nishimura S, Ezura M, Suzuki H, Uenohara H, Tominaga T: Subependymoma in the lateral ventricle manifesting as intraventricular hemorrhage. Neurol Med Chir (Tokyo); 2010;50(11):1020-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cerebral angiography revealed no abnormal findings.
  • Magnetic resonance imaging at 5 weeks after admission showed a tumor arising from the septum pellucidum or the floor of the right lateral ventricle, appearing as a mixed-intensity solid tumor, which was partially enhanced following gadolinium administration.
  • The tumor had arisen from the septum pellucidum and was totally removed via an interhemispheric anterior transcallosal approach.
  • Intraventricular hemorrhage from cerebral neoplasms is usually due to highly vascular tumors.
  • Since subependymomas are quite benign and show poor vascularity, intraventricular or subarachnoid hemorrhages are very rare, but do occasionally occur.
  • [MeSH-major] Cerebral Hemorrhage / etiology. Cerebral Ventricle Neoplasms / complications. Cerebral Ventricle Neoplasms / diagnosis. Glioma, Subependymal / complications. Glioma, Subependymal / diagnosis. Lateral Ventricles / pathology

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  • (PMID = 21123990.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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66. Chryssagis K, Liangos A, Westhof F, Batz G, Diegeler A: Transesophageal echocardiography for detection of a papillary fibroelastoma of the aortic valve. Hellenic J Cardiol; 2010 Mar-Apr;51(2):170-4
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  • Papillary fibroelastoma (PF) is a benign cardiac tumor, typically attached to the cardiac valves.
  • It is rarely symptomatic, but can cause myocardial infarction, cerebral infarction and systemic embolism, even in young patients, and sometimes results in sudden death.
  • After complete surgical removal of the tumor, we reconstructed the left coronary cusp with autologous pericardium.

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  • (PMID = 20378521.001).
  • [ISSN] 2241-5955
  • [Journal-full-title] Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē
  • [ISO-abbreviation] Hellenic J Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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67. Jang SW, Kim SJ, Kim SM, Lee JH, Choi CG, Lee DH, Kim EJ, Lee JK: MR spectroscopy and perfusion MR imaging findings of intracranial foreign body granuloma: a case report. Korean J Radiol; 2010 May-Jun;11(3):359-63
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  • We report a case of intracranial foreign body granuloma that showed features of a high grade tumor on magnetic resonance (MR) imaging.
  • However, the relative cerebral blood volume was not increased in the enhancing mass on perfusion MRI and the choline/creatine ratio only slightly increased on MR spectroscopy.
  • The results suggest that the lesion is benign in nature.

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  • (PMID = 20461191.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
  • [Other-IDs] NLM/ PMC2864864
  • [Keywords] NOTNLM ; Magnetic resonance (MR), brain / Magnetic resonance (MR), perfusion / Magnetic resonance (MR), pseudotumor / Magnetic resonance (MR), spectroscopy
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68. Marhold F, Preusser M, Dietrich W, Prayer D, Czech T: Clinicoradiological features of rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: report of four cases and literature review. J Neurooncol; 2008 Dec;90(3):301-8
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  • [Title] Clinicoradiological features of rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: report of four cases and literature review.
  • BACKGROUND: Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a recently characterized rare tumor entity.
  • Despite benign histological features and a reported favorable postoperative course, there is still limited clinical experience with this tumor.
  • RESULTS: Patient 1 presented on an emergency basis due to intratumoral hemorrhage and tumor enlargement followed by life-threatening obstructive hydrocephalus.
  • CONCLUSIONS: The spectrum of presenting symptoms of RGNT is wide, nonspecific, and typically depends on tumor size and extent.
  • This tumor entity should be considered in the differential diagnosis of posterior fossa masses in order to avoid undue surgical aggressiveness.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnostic imaging. Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / diagnostic imaging. Ganglioglioma / diagnostic imaging. Ganglioglioma / pathology

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  • (PMID = 18777116.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 14
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69. Gessi M, Legnani FG, Maderna E, Casali C, Solero CL, Pollo B, DiMeco F: Mucinous low-grade adenocarcinoma arising in an intracranial enterogenous cyst: case report. Neurosurgery; 2008 Apr;62(4):E972-3; discussion E973
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  • OBJECTIVE: Enterogenous cysts (ECs) of the central nervous system are developmental malformations that occur in the spinal canal, posterior fossa, or cerebral hemispheres.
  • They are usually benign lesions, and malignant transformation is rare.
  • Subsequent follow-up computed tomographic scans showed progression of the residual tumor.

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  • (PMID = 18496166.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Zhou Y, Liu F, Xu Q, Wang X: Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancy. J Exp Clin Cancer Res; 2010;29:138
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  • [Title] Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancy.
  • The aim of this study was to examine the expression profile of DKK-1 gene in human glioma and its association with tumor malignancy.
  • A total of 47 tumor biopsy specimens and 11 normal brain tissue samples from patients with cerebral trauma internal decompression were embedded in paraffin blocks and used for immunostaining.
  • We further examined serologic concentrations and cerebral fluid levels of DKK-1 in patients with tumors.
  • RESULTS: DKK-1 could only be detected in 12 human glioblastoma cell lines, not in a panel of other tumor and normal cell lines.
  • Kendall's tau-c association analysis also revealed the increased DKK-1 protein expression in tumor tissues of higher pathologic classification.
  • The levels of cerebral fluid DKK-1 protein were significantly higher in glioma patients than in healthy donors or in neuronal benign tumor patients, suggesting that the DKK-1 molecule in cerebral fluids can be applicable to detect the presence of glioma and be developed as a novel prognostic treatment.
  • [MeSH-major] Biomarkers, Tumor / analysis. Brain Neoplasms / genetics. Gene Expression Profiling. Glioma / genetics. Intercellular Signaling Peptides and Proteins / metabolism

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  • (PMID = 21029453.001).
  • [ISSN] 1756-9966
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DKK1 protein, human; 0 / Intercellular Signaling Peptides and Proteins
  • [Other-IDs] NLM/ PMC2990739
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71. Saad A, Folkerth R, Poussaint T, Smith E, Ligon K: Meningioangiomatosis associated with meningioma: a case report. Acta Cytol; 2009 Jan-Feb;53(1):93-7
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  • BACKGROUND: Meningioangiomatosis is a meningovascular disorder that only rarely occurs in association with a meningioma.
  • Occasionally, as in this case, imaging studies do not readily identify this disorder as a benign process.
  • In addition, this disorder may infiltrate the underlying cerebral cortex, simulating, intraoperatively, a malignant infiltrative process.
  • To allow better recognition of this disorder, we report a case with emphasis on the unique cytologic features of the 2 components (meningioangiomatosis and meningioma) and potential pitfalls in diagnosis.
  • Neuroimaging showed an ill-defined signal abnormality in the left frontal lobe suggestive of a high-grade tumor.
  • Tumor resection was performed, and intraoperative smear preparation showed meningioangiomatosis associated with meningioma.

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  • (PMID = 19248561.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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72. Wang L, Fan M, Ju W, Pang ZL, Zhu ZH, Li B, Xiao YJ, Zeng FQ, Xiao CG: [Endourological treatment of aged high-risk patients with benign prostate hyperplasia: a report of 283 cases]. Zhonghua Nan Ke Xue; 2010 Sep;16(9):803-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endourological treatment of aged high-risk patients with benign prostate hyperplasia: a report of 283 cases].
  • OBJECTIVE: To evaluate the safety and effectiveness of endourological techniques in the treatment of benign prostate hyperplasia (BPH) in aged high-risk patients.
  • METHODS: We used endourological techniques in the treatment of 283 BPH patients aged over 70 years and complicated with hydronephrosis, renal failure, heart failure, cerebral infarction, respiratory dysfunction, anemia, diabetes, bladder tumor, or prostate weight over 80 g, TURP (transurethral resection of the prostate) for 112 cases and PKRP (transurethral plasmakinetic resection of the prostate) for the other 171.

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  • (PMID = 21171264.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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73. Waseem M, Atkuri L, Laureta E: A febrile child with seizure and hemiparesis. Pediatr Emerg Care; 2006 Nov;22(11):718-21
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  • Although most febrile seizures are simple and benign, these seizures can infrequently create a diagnostic dilemma.
  • The diagnosis of cerebral venous thrombosis is challenging to emergency physicians because it can mimic the presentation of many other disorders, including ischemic and hemorrhagic stroke, tumor, and abscess.

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  • (PMID = 17110863.001).
  • [ISSN] 1535-1815
  • [Journal-full-title] Pediatric emergency care
  • [ISO-abbreviation] Pediatr Emerg Care
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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74. Ideguchi M, Kajiwara K, Yoshikawa K, Kato S, Fujii M, Fujisawa H, Suzuki M: Benign fibrous histiocytoma of the skull with increased intracranial pressure caused by cerebral venous sinus occlusion. J Neurosurg; 2009 Sep;111(3):504-8
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  • [Title] Benign fibrous histiocytoma of the skull with increased intracranial pressure caused by cerebral venous sinus occlusion.
  • The authors present a very rare case of benign fibrous histiocytoma of the skull with increased intracranial pressure caused by sinus occlusion.
  • Imaging findings showed that the skull tumor was located at the right occipital bone with bone disruption and a compressed right sigmoid sinus.
  • Immunohistochemical analysis showed that the tumor was positive for CD68, alpha1-antichymotrypsin, and alpha1-antitrypsin.
  • From these findings, the tumor was diagnosed as a primary benign fibrous histiocytoma of the skull.
  • [MeSH-major] Cranial Sinuses. Histiocytoma, Benign Fibrous / physiopathology. Intracranial Pressure. Skull Neoplasms / physiopathology

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  • (PMID = 19249956.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Patel R, Lynn KC: Masquerading myxoma. Am J Med Sci; 2009 Aug;338(2):161-3
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  • They are generally benign and most commonly arise from the left atrium.
  • The clinical course of the left atrial myxoma is characterized by symptoms resulting from obstructive, embolic, or "constitutional" effects of the tumor (Goodwin, Lancet.
  • Embolic ischemic symptom manifestations are typically cerebral, although they could be peripheral (Greenwood, Am Heart J. 1972;83:694).

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  • (PMID = 19680024.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Sarnat HB, Flores-Sarnat L: Embryology of the neural crest: its inductive role in the neurocutaneous syndromes. J Child Neurol; 2005 Aug;20(8):637-43
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  • Abnormal angiogenesis, areas of abnormal pigmentation that sometimes follow the lines of Blashko, nerve sheath proliferations, disorders of chromaffin tissue, lipomes and benign and malignant tumors are frequent features.
  • Many defective genes in neurocutaneous syndromes have an additional function as tumor suppressors.
  • The craniofacial abnormalities associated with many cerebral malformations and cutaneous lesions in some neurocutaneous syndromes emphasize an important inductive role of the neural tube in the development of non-neural tissues, mediated through neural crest.

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  • (PMID = 16225807.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 74
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77. Chen H, Sun XF, Wu JS: [Clinicopathologic study of subependymal giant cell astrocytoma]. Zhonghua Bing Li Xue Za Zhi; 2006 Nov;35(11):656-9
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  • The tumor often occurred in the lateral ventricles (16/18, 88.9%).
  • CONCLUSIONS: Subependymal giant cell astrocytoma is a benign brain tumor with distinctive histopathologic features.
  • The tumor typically affects children and young adults.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology

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  • (PMID = 17374208.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Synaptophysin
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78. Poliani PL, Sperli D, Valentini S, Armentano A, Bercich L, Bonetti MF, Corriero G, Brisigotti M, Quattrone A, Lanza PL: Spinal glioneuronal tumor with neuropil-like islands and meningeal dissemination: histopathological and radiological study of a pediatric case. Neuropathology; 2009 Oct;29(5):574-8
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  • [Title] Spinal glioneuronal tumor with neuropil-like islands and meningeal dissemination: histopathological and radiological study of a pediatric case.
  • Cerebral and spinal location of glioneuronal tumors have been recently described as a novel type of primary CNS neoplasia.
  • A distinctive rare form of glioneuronal tumors with neuropil-like islands (GTNI) have been reported to occur in the adult cerebrum, whereas spinal GTNI localization is extremely rare.
  • Histologically the tumor was composed of round, small neurocytic-like cells arranged around eosinophilic neuropil cores and embedded in a diffuse fibrillar glial component forming prominent "rosetted" neuropil islands displaying strong immunoreactivity for neuronal markers.
  • Cerebral GTNI shows abundant glial components not rarely exhibiting anaplastic features that justify their inclusion within the group of diffuse astrocytomas.
  • Nevertheless, due to their exceptional rarity, the natural history of these lesions is not yet fully understood, but spinal GTNI seems to have an unfavorable clinical course despite their benign histopathological features, which must be taken into account for appropriate treatment and follow-up of the patient.

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  • (PMID = 19077041.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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79. Balaji R, Ramachandran K: Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint. Childs Nerv Syst; 2009 Apr;25(4):497-501
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  • PURPOSE: Desmoplastic infantile gangliogliomas (DIG) are rare benign intracranial neoplasms of early childhood with involvement of superficial cerebral cortex and leptomeninges.
  • The purpose of the study was to determine the alterations in metabolite ratios occurring in the neoplasm and combine with magnetic resonance (MR) imaging features to narrow down the diagnosis.
  • Single-voxel short TE (1)H MR spectroscopy was used to study the changes in metabolite ratios in the tumor.
  • RESULTS: Comparison of metabolite ratios between normal brain tissue and tumor-affected region showed lower N-acetyl aspartate to creatine (Cr; 1.58 vs.1.28), higher choline to Cr (0.82 vs.2.03), and no significant change in myo-inositol to Cr (0.42 vs.0.39).

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  • (PMID = 19139903.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 30KYC7MIAI / Aspartic Acid; 4L6452S749 / Inositol; 997-55-7 / N-acetylaspartate; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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80. Luan S, Zhuang D, Sun L, Huang FP: Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature. Clin Neurol Neurosurg; 2010 May;112(4):362-4
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  • [Title] Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature.
  • Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been identified as a novel and distinctive type of primary central nervous system neoplasm.
  • RGNT of the fourth ventricle is a rare, benign tumor with an excellent prognosis.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Glioma / pathology. Rosette Formation

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  • [Copyright] Crown Copyright 2010. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20133047.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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81. Fayed-Miguel N, Morales-Ramos H, Modrego-Pardo PJ: [Magnetic resonance imaging with spectroscopy, perfusion and cerebral diffusion in the diagnosis of brain tumours]. Rev Neurol; 2006 Jun 16-30;42(12):735-42
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  • [Title] [Magnetic resonance imaging with spectroscopy, perfusion and cerebral diffusion in the diagnosis of brain tumours].
  • [Transliterated title] Resonancia magnética con espectroscopia, perfusión y difusión cerebral en el diagnóstico de los tumores cerebrales.
  • DEVELOPMENT AND CONCLUSIONS: Choline containing compounds using contralateral creatine and choline for normalization or ipsilateral N-acetyl-aspartate appeared to correlate best with the degree of tumor infiltration, regardless o tumor histological grade.
  • Magnetic resonance spectroscopy imaging (MRSI) seems more accurate than conventional magnetic resonance imaging (MRI) in defining indistinct tumor boundaries and quantifying the degree of tumor infiltration.
  • Angiogenesis, and increased vascular permeability, are characteristic of cerebral neoplasms; these processes can be imaged using perfusion MRI.
  • Most commonly, tumor perfusion is measured using rapid gradient T2-weighted imaging during bolus injection of gadolinium dimeglumine gadopentetate.
  • Cerebral blood volume increases with tumor grade, and maybe helpful in identifying tumor recurrence, and peri-tumoral edema, and distinguishing malignant from benign lesions.
  • [MeSH-minor] Aspartic Acid / analogs & derivatives. Aspartic Acid / metabolism. Biomarkers, Tumor / chemistry. Biomarkers, Tumor / metabolism. Blood-Brain Barrier / physiology. Brain Chemistry. Cerebrovascular Circulation. Choline / chemistry. Choline / metabolism. Contrast Media / metabolism. Image Processing, Computer-Assisted. Neoplasm Staging. Permeability. Prognosis

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  • (PMID = 16775800.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Contrast Media; 30KYC7MIAI / Aspartic Acid; 997-55-7 / N-acetylaspartate; N91BDP6H0X / Choline
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82. Shingu T, Akiyama Y, Daisu M, Maruyama N, Matsumoto Y, Miyazaki T, Nagai H, Yamamoto Y, Yamasaki T, Yoshida M, Maruyama R, Moritake K: Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report. Neurol Med Chir (Tokyo); 2007 May;47(5):222-8
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  • Computed tomography and T(2)*-weighted magnetic resonance imaging revealed hemorrhage in the tumor located in the right basal ganglia, thalamus, and hypothalamus.
  • Although neither symptomatic hemorrhage nor late benign recurrence is common, careful long-term follow up is necessary for patients with pilocytic astrocytoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Cerebral Hemorrhage / etiology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17527050.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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83. Richards J, Ballard N: Colloid cyst: a case study. J Neurosci Nurs; 2008 Apr;40(2):103-5
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  • A colloid cyst, also called a neuroepithelial cyst, is a slow-growing, benign tumor that occurs in the anterior third ventricle.
  • Less common presenting signs and symptoms include nausea, vomiting, memory loss, mental status changes, gait disorder, and visual disturbances.
  • [MeSH-major] Cerebral Ventricle Neoplasms / diagnosis. Cerebral Ventricle Neoplasms / surgery. Cysts / diagnosis. Cysts / surgery. Third Ventricle

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  • (PMID = 18481740.001).
  • [ISSN] 0888-0395
  • [Journal-full-title] The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
  • [ISO-abbreviation] J Neurosci Nurs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Ahn ES, Chin LS, Gyure KA, Hudes RS, Ragheb J, DiPatri AJ Jr: Long-term control after resection and gamma knife surgery of an intracranial clear cell meningioma: case report. J Neurosurg; 2005 Apr;102(3 Suppl):303-6
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  • Authors have described its propensity to recur and metastasize despite its benign pathological characteristics.
  • Initially, the residual tumor decreased in size, but 6 years later, it had regrown (9 mm in size).
  • [MeSH-major] Meningeal Neoplasms / surgery. Meningioma / surgery. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery. Stereotaxic Techniques
  • [MeSH-minor] Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Child. Dominance, Cerebral / physiology. Female. Follow-Up Studies. Glycogen / metabolism. Humans. Image Enhancement. Magnetic Resonance Imaging. Neurologic Examination. Reoperation. Temporal Lobe / pathology. Temporal Lobe / surgery. Tomography, X-Ray Computed

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  • (PMID = 15881755.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9005-79-2 / Glycogen
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85. Kinfe TM, Tschan CA, Stan AC, Krauss JK: Solitary fibrous tumor of the foramen of Monro. Clin Neurol Neurosurg; 2008 Apr;110(4):404-7
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  • [Title] Solitary fibrous tumor of the foramen of Monro.
  • This benign entity shows histoimmunochemically strong positivity for vimentin and calretinin.
  • Imaging studies demonstrated a tumor at the foramen of Monro which was thought to be a colloid cyst and she underwent CSF shunting.
  • After recurrent episodes of shunt dysfunction the tumor was removed via a transventricular approach guided by endoscopic ventriculoscopy.
  • The histopathological examination revealed a solitary fibrous tumor.
  • This is the first report on a solitary fibrous tumor located at the foramen of Monro in an elderly patient.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Cerebral Ventricles / surgery. Solitary Fibrous Tumors / surgery

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  • (PMID = 18243526.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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86. Katakowski M, Jiang F, Zheng X, Gutierrez JA, Szalad A, Chopp M: Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17. Cancer Sci; 2009 Sep;100(9):1597-604
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  • When implanted in the nude mouse brain, CTX-TNA2 cells induced low histological grade, benign intraventricular gliomas.

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  • (PMID = 19515085.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA043892-17; United States / NCI NIH HHS / CA / R01 CA100486-04; United States / NCI NIH HHS / CA / P01 CA043892; United States / NCI NIH HHS / CA / CA100486-04; United States / NCI NIH HHS / CA / R01 CA100486; United States / NCI NIH HHS / CA / P01 CA043892-17
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / RNA, Messenger; 0 / Tumor Necrosis Factor-alpha; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.4.24.- / ADAM Proteins; EC 3.4.24.- / tumor necrosis factor-alpha convertase
  • [Other-IDs] NLM/ NIHMS142282; NLM/ PMC2756136
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87. Giuşcă S, Jurcuţ R, Serban M, Popescu BA, Apetrei E, Ginghină C: Cardiac tumors: the experience of a tertiary cardiology center. Rom J Intern Med; 2007;45(4):333-9
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  • RESULTS: In the CTum group (49 +/- 16.2 years, similar between men and women), the main symptoms leading to patients referral were dyspnea (15 pts, 62.5%) and embolic events (coronary, cerebral, peripheral arteries: 7 pts, 29%), while in 4 asymptomatic pts the diagnosis was incidental.
  • In 20 pts (83%), TTE and transesophageal echocardiography (TEE) provided all the data required for preoperative assessment (tumor size, extension, location, insertion site).
  • The imaging techniques suggested a diagnosis of benign tumor in 15 pts (62.5%) and malignant tumor in 5 pts.
  • In 4 pts the tumor type could not be established.
  • In the case of benign tumors, surgery must be performed as soon as possible after the diagnosis has been established, whereas for malignant tumors there is still much controversy in what regards the benefits of surgery.

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  • (PMID = 18767408.001).
  • [ISSN] 1220-4749
  • [Journal-full-title] Romanian journal of internal medicine = Revue roumaine de médecine interne
  • [ISO-abbreviation] Rom J Intern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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88. Messing-Jünger AM, Riemenschneider MJ, Reifenberger G: A 21-year-old female with a third ventricular tumor. Brain Pathol; 2006 Jan;16(1):87-8, 93
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  • [Title] A 21-year-old female with a third ventricular tumor.
  • Intraoperatively, the tumor showed a close relationship to the choroid plexus of the third ventricle.
  • Histopathology revealed a benign schwannoma of World Health Organization grade I.
  • Most of these tumors were benign schwannomas, except for 2 cases of malignant peripheral nerve sheath tumors.
  • The tumor of our patient is the first reported schwannoma of the third ventricle.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Neurilemmoma / pathology. Neurilemmoma / surgery

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  • (PMID = 16612987.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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89. Caballero PE: Left atrial sarcoma presenting as cerebral infarction. Neurologist; 2008 Mar;14(2):131-3
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  • [Title] Left atrial sarcoma presenting as cerebral infarction.
  • OBJECTIVE: Primary heart tumors are rare and most of them are benign.
  • The majority of benign cardiac tumors are myxomas, although almost all malignant cardiac tumors are sarcomas.
  • METHODS: There have been cases described of stroke secondary to embolism caused by cardiac sarcomas, but it is rarely the first manifestation of the tumor.
  • [MeSH-major] Cerebral Infarction / etiology. Heart Neoplasms / complications. Intracranial Embolism / etiology. Sarcoma / complications

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  • (PMID = 18332844.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Mainio A, Tuunanen S, Hakko H, Niemelä A, Koivukangas J, Räsänen P: Decreased quality of life and depression as predictors for shorter survival among patients with low-grade gliomas: a follow-up from 1990 to 2003. Eur Arch Psychiatry Clin Neurosci; 2006 Dec;256(8):516-21
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  • OBJECTIVES: To assess the long-term survival of brain tumor patients, and in particular to evaluate the relation of quality of life (QOL) to survival among low-grade glioma patients.
  • METHODS: The postoperative survival of 101 brain tumor patients was followed from surgery (1990-1992) until the end of the year 2003.
  • RESULTS: The mean survival times in years (SD) were significantly related to tumor malignancy, being the shortest, 1.9 (0.6), for patients with high-grade gliomas, while patients with low-grade gliomas or a benign brain tumor had mean survival times of 9.1 (1.0) and 11.6 (0.5), respectively.
  • [MeSH-major] Brain Neoplasms / mortality. Brain Neoplasms / psychology. Depressive Disorder / mortality. Depressive Disorder / psychology. Glioma / mortality. Glioma / psychology. Quality of Life / psychology
  • [MeSH-minor] Adult. Aged. Disease Progression. Dominance, Cerebral / physiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Postoperative Complications / mortality. Postoperative Complications / psychology. Prognosis. Statistics as Topic. Survival Analysis


91. Pascual-Castroviejo I, Pascual-Pascual SI, Velázquez-Fragua R, Viaño J, Carceller-Benito F: [Aqueductal stenosis in the neurofibromatosis type 1. Presentation of 19 infantile patients]. Rev Neurol; 2007 Jul 1-15;45(1):18-21
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  • [Transliterated title] Estenosis del acueducto de Silvio en la neurofibromatosis tipo 1. Presentación de 19 pacientes infantiles.
  • All patients, except one who died before the imaging study was performed and was diagnosed by autopsy, were studied by pneumoencephalography (since 1965 to 1974), computerized tomography (CT) (since 1975 to 1984), magnetic resonance (MR) or MR and CT (since 1985 to 2004) (two children had been studied by pneumoencephalography some years before) most times to discard optic pathway tumor and, in few patients, because of intracranial hypertension.
  • Eleven patients showed optic pathway tumor.
  • One patient had a benign aqueductal tumor that impaired the normal flow of cerebrospinal fluid.
  • Aqueductal stenosis and hydrocephalus were identified at a short age because many patients were studied suspecting optic pathway tumor.
  • Eleven patients (about 60%) associated optic pathway tumor and aqueductal stenosis.
  • [MeSH-major] Cerebral Aqueduct / pathology. Constriction, Pathologic / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 17620261.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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92. Pui MH, Wang Y: Diffusion and magnetization transfer MRI of brain infarct, infection, and tumor in children. Clin Imaging; 2005 May-Jun;29(3):162-71
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  • [Title] Diffusion and magnetization transfer MRI of brain infarct, infection, and tumor in children.
  • The purpose of this study was to determine the efficacy of diffusion-weighted imaging (DWI) and magnetization transfer imaging (MTI) in the differential diagnosis of brain infarct, infection, hamartoma, and tumor in 106 children.
  • There was an inverse relationship between ADC and MTR in subacute/chronic infarct, infection, hamartoma, arachnoid cyst, and tumor relative to normal brain parenchyma.
  • DWI and MTI had a complementary role in the differential diagnosis of acute infarct from infection with lower MTR, from hamartoma with higher ADC, and from low-grade gliomas and benign tumors that had higher ADCs and lower MTRs.
  • ADCs increased and MTRs decreased with the duration of infarct and lower tumor grade.
  • [MeSH-major] Brain / pathology. Brain Neoplasms / diagnosis. Central Nervous System Infections / diagnosis. Cerebral Infarction / diagnosis. Diffusion Magnetic Resonance Imaging. Image Processing, Computer-Assisted

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  • (PMID = 15855060.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Arai A, Sasayama T, Tamaki M, Sakagami Y, Enoki E, Ohbayashi C, Kohmura E: Rosette-forming glioneuronal tumor of the fourth ventricle--case report. Neurol Med Chir (Tokyo); 2010;50(3):224-8
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  • [Title] Rosette-forming glioneuronal tumor of the fourth ventricle--case report.
  • Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a rare tumor included as a novel glioneuronal neoplasm in the 2007 World Health Organization classification of brain tumors.
  • The tumor was gross totally resected.
  • The prognosis is benign, but relatively aggressive behaviors such as tumor growth, recurrence, and acute deterioration due to intratumoral hemorrhaging can occur.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Infratentorial Neoplasms / pathology. Neoplasms, Neuroepithelial / pathology. Teratoma / pathology

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  • (PMID = 20339273.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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94. Kawaguchi T, Kumabe T, Shimizu H, Watanabe M, Tominaga T: 201Tl-SPECT and 1H-MRS study of benign lateral ventricle tumors: differential diagnosis of subependymoma. Neurosurg Rev; 2005 Apr;28(2):96-103
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  • [Title] 201Tl-SPECT and 1H-MRS study of benign lateral ventricle tumors: differential diagnosis of subependymoma.
  • Our study includes nine cases of benign lateral ventricle tumors including two cases of central neurocytoma, two of subependymal giant cell astrocytoma, two of pilocytic astrocytoma and three of subependymoma treated surgically between 1996 and 2003.
  • All three types of tumor demonstrated heterogeneous enhancement on MR imaging with gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and increased choline (Cho) peak and decreased N-acetyl aspartate (NAA) and creatine (Cre) peaks on (1)H-MRS. (201)Tl-SPECT showed high uptake of (201)Tl without wash out in all cases of central neurocytoma, subependymal giant cell astrocytoma and pilocytic astrocytoma, but no uptake in cases of subependymoma.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebral Ventricle Neoplasms / diagnosis. Glioma, Subependymal / diagnosis. Lateral Ventricles. Neurocytoma / diagnosis

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  • (PMID = 15580370.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
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95. Lauretti L, Fernandez E, Pallini R, Massimi L, Albanese A, Denaro L, Maira G: Long survival in an untreated solitary choroid plexus metastasis from renal cell carcinoma: case report and review of the literature. J Neurooncol; 2005 Jan;71(2):157-60
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  • For several years, such metastasis was interpreted as a benign intraventricular tumor and was not treated.
  • We think that this unusual biological behaviour of the tumor determined the late inset of the neurological symptoms, despite the location at the choroid plexus that usually leads to an early obstructive hydrocephalus.
  • [MeSH-minor] Aged. Cerebral Angiography. Female. Humans. Magnetic Resonance Imaging. Survival Analysis

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  • (PMID = 15690132.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
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96. Yeh IB, Xu M, Ng WH, Ye J, Yang D, Lim CC: Central neurocytoma: typical magnetic resonance spectroscopy findings and atypical ventricular dissemination. Magn Reson Imaging; 2008 Jan;26(1):59-64
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  • The surgically resected tumor specimen of one of these patients was also studied ex vivo using high-resolution magic angle spinning (HRMAS) nuclear magnetic resonance.
  • In six patients, CNC extended into the third ventricle, and in two patients the tumor showed further contiguous intraventricular dissemination into the fourth ventricle.
  • Although they are rare benign intraventricular tumors, in atypical cases, CNCs can show extensive intraventricular dissemination into the fourth ventricle.
  • [MeSH-major] Cerebral Ventricle Neoplasms / metabolism. Cerebral Ventricles / pathology. Magnetic Resonance Spectroscopy. Neurocytoma / metabolism

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  • (PMID = 17574365.001).
  • [ISSN] 0730-725X
  • [Journal-full-title] Magnetic resonance imaging
  • [ISO-abbreviation] Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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97. Pascual Castroviejo I, Pascual Pascual S, Velázquez Fragua R, Viaño J, Garcia Segura JM: [Brain stem tumors associated with neurofibromatosis type 1. Presentation of 20 infantile patients]. Neurologia; 2007 Dec;22(10):846-52
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  • [Transliterated title] Tumores de tronco cerebral asociados con neurofibromatosis tipo 1. Presentación de 20 pacientes infantiles.
  • Thirteen of the 20 patients (65 %) also had optic pathway tumor.
  • Brain stem tumor identification occurred at the same time as NF1 in the patients who were studied by MR at the time of the first consult.
  • Diffuse or localized medullary enlargement was the most frequent MR imaging and appeared in 13 patients (65%), followed by the tumor that involved all brain stem (pontine and medullary areas) that appeared in 6 patients (30 %).
  • In the last group, one tumor showed extension through brain stem and medial cerebellar parts, another was located in the aqueduct and in the periaqueductal areas and showed slow progressive growth, and one third patient had a tumor with aggressive signs in the SMR study.
  • Another patient had an aggressive tumor that involved the left optic nerve, chiasm, mesencephalon and upper right pontine areas.
  • The histological study of the tumoral biopsic tissue of the two last patients showed astrocitoma degree 1 (benign tumor).
  • Only one of the 20 patients died, although it was due to a malignant chiasmatic tumor, that had been treated twenty years before, and not by the brain stem tumor.
  • MR and SMR are necessary to a correct identification of the tumor in some patients.
  • Most of these tumors are benign.


98. Scherer K, Johnston J, Panda M: Dural based mass: malignant or benign. J Radiol Case Rep; 2009;3(11):1-12
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  • [Title] Dural based mass: malignant or benign.
  • Cerebral angiogram demonstrated a parafalcine mass supplied by the middle meningeal artery.
  • This paper additionally discusses the differentiation of benign dural based tumors like meningiomas from malignant findings.
  • Multiple adjunct studies can differentiate meningiomas from metastatic tumor.

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  • (PMID = 22470624.001).
  • [ISSN] 1943-0922
  • [Journal-full-title] Journal of radiology case reports
  • [ISO-abbreviation] J Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3303278
  • [Keywords] NOTNLM ; Dural based mass / meningioma / metastatic dural based lesions
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99. Wang FL, Li XH, Gui QP, Liu L: [Clinicopathologic and radiologic features of dysembryoplastic neuroepithelial tumors]. Zhonghua Bing Li Xue Za Zhi; 2005 Sep;34(9):566-8
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  • OBJECTIVE: To study the clinicopathologic features and radiologic findings of dysembryoplastic neuroepithelial tumor (DNT).
  • All tumors were located in the supratentorial cerebral cortex.
  • CONCLUSIONS: DNT is a benign tumor with excellent prognosis after surgical excision.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebral Cortex / pathology. Neuroectodermal Tumors, Primitive / pathology

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  • (PMID = 16468306.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Neurofilament Proteins; 0 / S100 Proteins; 0 / Synaptophysin
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100. Kawahara I, Nakamoto M, Matsuo Y, Tokunaga Y: [Subclavian steal phenomenon associated with hypervascular thyroid tumor]. No Shinkei Geka; 2010 May;38(5):473-6
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  • [Title] [Subclavian steal phenomenon associated with hypervascular thyroid tumor].
  • The patient was hospitalized with acute cerebral infarction due to middle cerebral artery (MCA) severe stenosis.
  • Thyroid tumor was regarded as benign by radiological findings, laboratory data, and physical examination.
  • If SSS becomes symptomatic, removal of the thyroid tumor may be indicated.
  • [MeSH-minor] Aged. Cerebral Angiography. Female. Humans

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  • (PMID = 20522919.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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