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Items 1 to 89 of about 89
1. Amini A, Osborn AG, McCall TD, Couldwell WT: Remote cerebellar hemorrhage. AJNR Am J Neuroradiol; 2006 Feb;27(2):387-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Remote cerebellar hemorrhage.
  • Remote cerebellar hemorrhage (RCH) is a rare but benign, self-limited complication of supratentorial craniotomies that, to the best of our knowledge, has not been described in the imaging literature.
  • Cerebellar hemorrhage in the typical setting can be identified as RCH and does not require more extensive or invasive evaluation.
  • [MeSH-major] Brain Injuries / surgery. Brain Neoplasms / surgery. Cerebellar Diseases / diagnosis. Craniotomy. Image Enhancement. Image Processing, Computer-Assisted. Intracranial Aneurysm / surgery. Intracranial Hemorrhages / diagnosis. Magnetic Resonance Imaging. Postoperative Complications / diagnosis. Tomography, X-Ray Computed. Wounds, Gunshot / surgery


2. Hayashi S, Takeda N, Komura E: Symptomatic cerebellar hemorrhage from recurrent hemangioblastoma during delivery. Case report. Neurol Med Chir (Tokyo); 2010;50(12):1105-7
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  • [Title] Symptomatic cerebellar hemorrhage from recurrent hemangioblastoma during delivery. Case report.
  • A 30-year-old woman suffered cerebellar hemorrhage during the delivery of her first child.
  • She had undergone surgical removal of a symptomatic cerebellar hemangioblastoma 6 years previously.
  • Hemangioblastomas are benign tumors that are curable with surgical removal, but can grow during pregnancy.
  • [MeSH-major] Cerebellar Neoplasms / complications. Cerebellum / blood supply. Hemangioblastoma / complications. Intracranial Hemorrhages / etiology. Neoplasm Recurrence, Local / complications

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  • (PMID = 21206188.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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3. Mittal P, Gupta K, Saggar K, Kaur S: Adult medulloblastoma mimicking Lhermitte-Duclos disease: can diffusion weighted imaging help? Neurol India; 2009 Mar-Apr;57(2):203-5
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  • Lhermitte-Duclos disease, also known as dysplastic cerebellar gangliocytoma, is a rare cerebellar benign tumor with characteristic appearance of thickened cerebellar folia giving a laminated or striated appearance, quite diagnostic of the condition.
  • We had seen a patient with medulloblastoma with imaging findings suspicious for thickened cerebellar folia reminiscent of Lhermitte-Duclos disease.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging. Hamartoma Syndrome, Multiple / diagnosis. Medulloblastoma / diagnosis

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  • (PMID = 19439857.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Contrast Media
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4. González-Tortosa J, Ferri-Níguez B, Ros de San Pedro J: [Cerebellopontine angle meningeal melanocytoma: a benign tumor?]. Neurocirugia (Astur); 2009 Aug;20(4):372-9; discussion 379-80
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  • [Title] [Cerebellopontine angle meningeal melanocytoma: a benign tumor?].
  • [Transliterated title] Melanocitoma meníngeo del ángulo pontocerebeloso: un tumor benigno?
  • One year after tumor gross total removal, the patient suffered a sudden and devastating meningeal melanomatosis.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Melanocytes / pathology. Meningeal Neoplasms / pathology. Nevus / pathology
  • [MeSH-minor] Antineoplastic Agents, Alkylating / therapeutic use. Diagnosis, Differential. Disease Progression. Fatal Outcome. Gait Disorders, Neurologic / etiology. Hearing Loss, Sensorineural / etiology. Humans. Magnetic Resonance Imaging. Male. Melanoma / diagnosis. Melanoma / pathology. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / pathology. Neurilemmoma / diagnosis. Nitrosourea Compounds / therapeutic use. Organophosphorus Compounds / therapeutic use

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  • (PMID = 19688139.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Nitrosourea Compounds; 0 / Organophosphorus Compounds; GQ7JL9P5I2 / fotemustine
  • [Number-of-references] 44
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5. Cianfoni A, Wintermark M, Piludu F, D'Alessandris QG, Lauriola L, Visocchi M, Colosimo C: Morphological and functional MR imaging of Lhermitte-Duclos disease with pathology correlate. J Neuroradiol; 2008 Dec;35(5):297-300
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  • Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture.
  • [MeSH-major] Brain Neoplasms / diagnosis. Hamartoma Syndrome, Multiple / diagnosis. Magnetic Resonance Imaging / methods

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  • (PMID = 18692898.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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6. Callu D, Viguier D, Laroussinie F, Puget S, Boddaert N, Kieffer V, Piana H, Escolano S, Renier D, Sainte-Rose C, Grill J, Dellatolas G: Cognitive and academic outcome after benign or malignant cerebellar tumor in children. Cogn Behav Neurol; 2009 Dec;22(4):270-8

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  • [Title] Cognitive and academic outcome after benign or malignant cerebellar tumor in children.
  • OBJECTIVE: To examine the impact of malignancy and location of the cerebellar tumor on motor, cognitive, and psychologic outcome.
  • BACKGROUND: Although many studies focus on long-term outcome after cerebellar tumor treatment in childhood, the impact of its precise location remains unclear.
  • PATIENTS AND METHODS: Children, aged from 6 to 13 years, with a cerebellar malignant tumor (MT; MT group, n=20) or a cerebellar benign tumor (BT; BT group, n=19) were examined at least 6 months after the end of treatment using the international cooperative ataxia rating scale, the Purdue pegboard for manual skill assessment and the age-adapted Weschler scale.
  • RESULTS: Parents and teachers reported high rate of learning and academic difficulties, but without any difference with respect to the type of tumor.
  • However, children with cerebellar MT showed increased cognitive and motor difficulties compared with children with cerebellar BT.
  • Cerebellar signs at clinical examination and manual skill impairment were strongly associated with cognitive difficulties.
  • CONCLUSIONS: Dentate nuclei lesions are major risk factors of motor and cognitive impairments in both cerebellar BT and MT.
  • [MeSH-major] Achievement. Cerebellar Neoplasms / therapy. Cognition. Glioma / therapy
  • [MeSH-minor] Adolescent. Cerebellum / surgery. Cerebrospinal Fluid Shunts. Child. Female. Humans. Image Processing, Computer-Assisted. Language Tests. Magnetic Resonance Imaging. Male. Motor Skills / physiology. Neuropsychological Tests. Patient Selection. Surveys and Questionnaires. Treatment Outcome

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  • (PMID = 19996881.001).
  • [ISSN] 1543-3641
  • [Journal-full-title] Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
  • [ISO-abbreviation] Cogn Behav Neurol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Schoch B, Hogan A, Gizewski ER, Timmann D, Konczak J: Balance control in sitting and standing in children and young adults with benign cerebellar tumors. Cerebellum; 2010 Sep;9(3):324-35
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  • [Title] Balance control in sitting and standing in children and young adults with benign cerebellar tumors.
  • Children and young adolescents with chronic surgical cerebellar lesions show persistent balance control problems during standing when lesions affect the deep cerebellar fastigial and adjacent interposed nuclei.
  • Balance control was assessed in 16 patients after surgery of a benign cerebellar tumor in chronic state and healthy age- and gender-matched control subjects.
  • High-resolution MRI scans were acquired in the cerebellar patients.
  • During sitting, 56% of cerebellar patients exhibited trunkal sway outside the range of healthy controls, and 87.5% of cerebellar patients revealed abnormal sway patterns during standing.
  • In patients with surgery <1-year lesions of the inferior cerebellar vermis also had an impact on balance function.
  • Our results corroborate previous evidence that the extent of permanent damage to the deep cerebellar nuclei greatly impacts on the recovery on balance function.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Neurosurgical Procedures / adverse effects. Postoperative Complications / physiopathology. Postural Balance
  • [MeSH-minor] Adolescent. Adult. Biomechanical Phenomena. Cerebellum / pathology. Cerebellum / physiopathology. Cerebellum / surgery. Child. Female. Humans. Male. Posture. Young Adult

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  • (PMID = 20352395.001).
  • [ISSN] 1473-4230
  • [Journal-full-title] Cerebellum (London, England)
  • [ISO-abbreviation] Cerebellum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Afshar-Oromieh A, Linhart H, Podlesek D, Schrempf W, Schackert G, Krex D: Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease. Neurosurg Rev; 2010 Oct;33(4):401-8
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  • [Title] Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease.
  • Cerebellar mutism (CM) is a rare and severe form of speech and language impairment, mostly diagnosed in children and adolescents and rarely reported in adults.
  • LDD is a rare benign cerebellar tumor.
  • However, surgery is hampered by the difficulty to distinguish between tumor and healthy cerebellar tissue, which may result in extensive resection and cause neurological deficits such as CM.
  • [MeSH-minor] Adolescent. Adult. Aged. Cerebellar Diseases / etiology. Cerebellar Diseases / pathology. Cerebellar Diseases / psychology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Epilepsy, Absence / etiology. Ganglioneuroma / pathology. Ganglioneuroma / surgery. Headache / etiology. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Prognosis. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 20668902.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
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9. Hamlat A, Le Strat A, Guegan Y, Ben-Hassel M, Saikali S: Cerebellar pleomorphic xanthoastrocytoma: case report and literature review. Surg Neurol; 2007 Jul;68(1):89-94; discussion 94-5
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  • [Title] Cerebellar pleomorphic xanthoastrocytoma: case report and literature review.
  • BACKGROUND: PXA generally has histologic features characteristic of benign biological behavior, although malignant forms have been reported.
  • This neoplasm has also been observed in atypical locations.
  • METHODS: The authors report a case of cerebellar PXA with rapid malignant transformation in a 58-year-old woman and review the rare presentations and atypical features of this tumor.
  • RESULTS: Among the "unusual" locations, the most frequent is the cerebellum with 15 cases having been described, 9 in adults, with an average age of 33 years.
  • PXA in the posterior fossa had a higher rate of solid enhancing tumor (9/14).
  • CONCLUSIONS: The clinicopathologic features of cerebellar PXA show some differences from PXA located in the cerebral hemispheres.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 17537486.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 28
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10. Melone AG, Delfinis CP, Passacantilli E, Lenzi J, Santoro A: Intracranial extra-axial cavernous angioma of the cerebellar falx. World Neurosurg; 2010 Oct-Nov;74(4-5):501-4
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  • [Title] Intracranial extra-axial cavernous angioma of the cerebellar falx.
  • INTRODUCTION: Intracranial cavernous hemangiomas are benign vascular malformations that can be divided into intra-axial and extra-axial types.
  • CASE REPORT: The authors report a case of a cavernous angioma that occurred in the cerebellar falx of a 58-year-old man.
  • The patient underwent surgery with en-bloc removal of the tumor.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Dura Mater / pathology. Hemangioma, Cavernous, Central Nervous System / pathology. Infratentorial Neoplasms / pathology. Meningeal Neoplasms / pathology

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21492602.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Ilg W, Giese MA, Gizewski ER, Schoch B, Timmann D: The influence of focal cerebellar lesions on the control and adaptation of gait. Brain; 2008 Nov;131(Pt 11):2913-27
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  • [Title] The influence of focal cerebellar lesions on the control and adaptation of gait.
  • Cerebellar ataxic gait is influenced greatly by balance disorders, most likely caused by lesions of the medial zone of the cerebellum.
  • In this study, we analysed locomotion and goal-directed leg movements in 12 patients with chronic focal lesions after resection of benign cerebellar tumours.
  • The extent of the cortical lesion and possible involvement of the cerebellar nuclei was determined by 3D-MR imaging.
  • [MeSH-major] Cerebellar Nuclei / physiopathology. Gait Ataxia / physiopathology
  • [MeSH-minor] Adaptation, Physiological. Adolescent. Adult. Brain Mapping / methods. Cerebellar Neoplasms / surgery. Female. Gait. Humans. Leg / physiopathology. Magnetic Resonance Imaging / methods. Male. Movement. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Postural Balance. Psychomotor Performance. Walking. Weight-Bearing. Young Adult

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  • (PMID = 18835866.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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12. Berger A, Sadeh M, Tzur G, Shuper A, Kornreich L, Inbar D, Cohen IJ, Michowiz S, Yaniv I, Constantini S, Kessler Y, Merian N: Task switching after cerebellar damage. Neuropsychology; 2005 May;19(3):362-370
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Task switching after cerebellar damage.
  • The authors of this study investigated task switching following cerebellar damage.
  • The study group consisted of 7 children and adolescents (M age=13.8 years) who underwent surgical removal of a benign posterior fossa tumor.
  • They have important implications for our understanding of the cognitive sequelae of early cerebellar damage as well as the involvement of the cerebellum in task switching.
  • [MeSH-major] Brain Neoplasms / physiopathology. Cerebellar Diseases / physiopathology. Cognition / physiology. Infratentorial Neoplasms / physiopathology. Psychomotor Performance / physiology

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  • [Copyright] Copyright (c) 2005 APA, all rights reserved.
  • (PMID = 15910122.001).
  • [ISSN] 0894-4105
  • [Journal-full-title] Neuropsychology
  • [ISO-abbreviation] Neuropsychology
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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13. Shoman N, Longridge N: Cerebellar vermis lesions and tumours of the fourth ventricle in patients with positional and positioning vertigo and nystagmus. J Laryngol Otol; 2007 Feb;121(2):166-9
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  • [Title] Cerebellar vermis lesions and tumours of the fourth ventricle in patients with positional and positioning vertigo and nystagmus.
  • The most common form is benign paroxysmal positioning.
  • In this paper, we discuss more serious aetiologies in the differential diagnosis for patients presenting with a history suggestive of benign paroxysmal positioning vertigo.
  • We draw attention to the diagnosis of cerebellar vermis lesions and tumours of the fourth ventricle by presenting two cases of patients with positional nystagmus of so called benign paroxysmal type.
  • We review the literature on positional nystagmus, highlighting key findings on history and physical examination to aid in the correct diagnosis of benign paroxysmal positioning vertigo, and to differentiate it from the rare yet sinister central aetiologies that can present with positional vertigo of the benign positional type.
  • [MeSH-major] Cerebellar Neoplasms / complications. Nystagmus, Pathologic / etiology. Vertigo / etiology

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  • (PMID = 17059627.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Hopyan T, Laughlin S, Dennis M: Emotions and their cognitive control in children with cerebellar tumors. J Int Neuropsychol Soc; 2010 Nov;16(6):1027-38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Emotions and their cognitive control in children with cerebellar tumors.
  • A constellation of deficits, termed the cerebellar cognitive affective syndrome (CCAS), has been reported following acquired cerebellar lesions.
  • We studied emotion identification and the cognitive control of emotion in children treated for acquired tumors of the cerebellum.
  • Participants were 37 children (7-16 years) treated for cerebellar tumors (19 benign astrocytomas (AST), 18 malignant medulloblastomas (MB), and 37 matched controls (CON).
  • Children with cerebellar tumors identified emotion as accurately and quickly as controls (p > .05), although there was a significant interaction of emotions and group (p < .01), with the MB group performing less accurately identifying sad emotions, and both cerebellar tumor groups were impaired in the cognitive control of emotions (p < .01).
  • The fact that childhood acquired cerebellar tumors disrupt cognitive control of emotion rather than emotion identification provides some support for a model of the CCAS as a disorder, not so much of emotion as of the regulation of emotion by cognition.
  • [MeSH-major] Affective Symptoms / etiology. Cerebellar Neoplasms / complications. Cognition Disorders / etiology. Developmental Disabilities / etiology. Medulloblastoma / complications

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  • (PMID = 20887648.001).
  • [ISSN] 1469-7661
  • [Journal-full-title] Journal of the International Neuropsychological Society : JINS
  • [ISO-abbreviation] J Int Neuropsychol Soc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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15. Kovács T, Osztie E, Bodrogi L, Pajor P, Farsang M, Juhász C, Szirmai I: Cerebellar developmental venous anomalies with associated vascular pathology. Br J Neurosurg; 2007 Apr;21(2):217-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar developmental venous anomalies with associated vascular pathology.
  • Cerebellar developmental venous anomalies (CDVA) are benign conditions, although sometimes they are associated with haemorrhages and reported to be symptomatic.
  • Four patients had CDVA and an associated vascular pathology: two pontine cavernomas, one asymptomatic arteriovenous malformation (this is the first published case in the literature) and one cerebellar infarct with a developmental variation of the posterior fossa venous circulation.
  • In conclusion, CDVAs are benign, asymptomatic conditions, but they are sometimes associated with pathogenic malformations requiring detailed neuroradiological investigations.
  • [MeSH-major] Cerebellar Diseases / complications. Intracranial Arteriovenous Malformations / complications
  • [MeSH-minor] Adult. Brain Stem Neoplasms / complications. Brain Stem Neoplasms / pathology. Female. Follow-Up Studies. Hemangioma, Cavernous / complications. Hemangioma, Cavernous / pathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 17453792.001).
  • [ISSN] 0268-8697
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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16. Ushio M, Murofushi T, Iwasaki S: Subjective visual horizontal in patients with posterior canal benign paroxysmal positional vertigo. Acta Otolaryngol; 2007 Aug;127(8):836-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subjective visual horizontal in patients with posterior canal benign paroxysmal positional vertigo.
  • CONCLUSION: Patients with posterior canal benign paroxysmal positional vertigo (p-BPPV) could have mild excitation in the vestibular system on the affected side.
  • For comparison, 17 patients with vestibular neuritis and 45 patients with cerebello-pontine angle (CPA) tumor were also examined.
  • Conversely, deviation of SVH was toward the affected side down in 88.2% of patients with vestibular neuritis and in 75.6% of patients with CPA tumor.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cerebellar Neoplasms / complications. Cerebellar Neoplasms / physiopathology. Cerebellopontine Angle. Female. Follow-Up Studies. Humans. Male. Middle Aged. Severity of Illness Index. Vestibular Neuronitis / complications. Vestibular Neuronitis / physiopathology

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  • (PMID = 17762994.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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17. Gunny RS, Hayward RD, Phipps KP, Harding BN, Saunders DE: Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children. Pediatr Radiol; 2005 Nov;35(11):1086-91
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  • [Title] Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children.
  • BACKGROUND: Cerebellar low-grade astrocytomas (CLGAs) of childhood are benign tumours and are usually curable by surgical resection alone or combined with adjuvant radiotherapy.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Magnetic Resonance Imaging / methods. Neoplasm Recurrence, Local / pathology. Neoplasm Regression, Spontaneous / pathology. Risk Assessment / methods

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  • (PMID = 16047140.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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18. Buccoliero AM, Caldarella A, Bacci S, Gallina P, Taddei A, Di Lorenzo N, Romagnoli P, Taddei GL: Cerebellar liponeurocytoma: morphological, immunohistochemical, and ultrastructural study of a relapsed case. Neuropathology; 2005 Mar;25(1):77-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar liponeurocytoma: morphological, immunohistochemical, and ultrastructural study of a relapsed case.
  • Cerebellar liponeurocytoma is a rare and newly identified neoplasm found in adults which is reputed to be benign.
  • Histopathological aggressive features (mitoses and a high proliferation index as evaluated by MIB-1) were shown in the primary lesion and recurrence of the tumor.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Medulloblastoma / pathology. Neoplasm Recurrence, Local / pathology

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  • (PMID = 15822821.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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19. Schoch B, Konczak J, Dimitrova A, Gizewski ER, Wieland R, Timmann D: Impact of surgery and adjuvant therapy on balance function in children and adolescents with cerebellar tumors. Neuropediatrics; 2006 Dec;37(6):350-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of surgery and adjuvant therapy on balance function in children and adolescents with cerebellar tumors.
  • OBJECTIVES: This study examined the effects of posterior fossa tumor surgery and concomitant irradiation and/or chemotherapy on the long-term recovery of balance function in children and adolescent patients.
  • SUBJECTS AND METHODS: 22 patients, treated during childhood for a benign (n = 14) or malignant cerebellar tumor (n = 8), were examined in chronic state (mean latency between surgery and testing: 7.7 years, range 3 - 17 years).
  • All cerebellar lesions were documented by standardized and normalized MRI data.
  • RESULTS: Comparing the balance function of (i) children with or without affected cerebellar nuclei and (ii) children with and without adjuvant chemotherapy and/or radiotherapy revealed that damage to the cerebellar nuclei had more impact on neurological impairment than concomitant tumor therapy.
  • CONCLUSIONS: The study results indicate that the sparing of the deep cerebellar nuclei had the greatest impact on the recovery of balance function in pediatric patients treated for both a benign or malignant cerebellar tumor.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Postural Balance
  • [MeSH-minor] Adolescent. Cerebellar Nuclei / drug effects. Cerebellar Nuclei / pathology. Cerebellar Nuclei / radiation effects. Cerebellar Nuclei / surgery. Cerebellum / drug effects. Cerebellum / radiation effects. Cerebellum / surgery. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Cranial Irradiation. Female. Follow-Up Studies. Humans. Image Processing, Computer-Assisted. Infant. Magnetic Resonance Imaging. Male. Neurologic Examination / drug effects. Postoperative Complications / diagnosis. Postoperative Complications / pathology. Radiotherapy, Adjuvant

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  • (PMID = 17357037.001).
  • [ISSN] 0174-304X
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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20. Kasliwal MK, Suri A, Rishi A, Suri V, Sharma BS, Sarkar C: Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma. J Clin Neurosci; 2008 Dec;15(12):1401-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma.
  • Xanthogranulomas are a group of benign lesions with an incidence of 1.6-7.0% in various autopsy series.
  • Multicentric bilateral symptomatic cerebellar xanthogranuloma has not been reported previously.
  • We describe a 35-year-old man who presented with a complaint of vertigo, with nystagmus and left-side cerebellar signs found on clinical examination.
  • Radiological evaluation revealed bilateral cerebellar lesions abutting the cerebellopontine angle cistern.
  • The role of histopathology cannot be overemphasized in the diagnosis of this rare lesion and long-term follow-up is advised in cases managed conservatively owing to the propensity of this tumor to grow over time.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Granuloma / pathology. Xanthomatosis / pathology

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  • (PMID = 18952438.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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21. Czerny C, Nemec S, Krestan C, Gstöttner W: [Benign and malignant lesions in the region of the inner ear and cerebellopontine angle]. Radiologe; 2006 Mar;46(3):197-204

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign and malignant lesions in the region of the inner ear and cerebellopontine angle].
  • [Transliterated title] Benigne und maligne Veränderungen der Innenohr- und Kleinhirnbrückenwinkelregion.
  • Tumorous lesions in the region of the inner ear and cerebellopontine angle are very rare and can be classified into benign and malignant disease forms.
  • The coronary slices can be reconstructed from the axial datasets or in individual cases examined in the coronary plane.HRCT excellently demonstrates osseous lesions and in individual cases - e.g., exostoses - it can simply suffice to perform HRCT of the temporal bone, while HRCT is also excellent for detecting osseous lesions to determine whether the tumor is benign or malignant.MRI, on the other hand, excellently shows the extent of tumor spread because of its superb soft tissue contrast.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle / diagnostic imaging. Cerebellopontine Angle / pathology. Ear Neoplasms / diagnosis. Ear, Inner / diagnostic imaging. Ear, Inner / pathology

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  • (PMID = 16418859.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 23
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22. Gan YC, Connolly MB, Steinbok P: Epilepsy associated with a cerebellar arachnoid cyst: seizure control following fenestration of the cyst. Childs Nerv Syst; 2008 Jan;24(1):125-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epilepsy associated with a cerebellar arachnoid cyst: seizure control following fenestration of the cyst.
  • OBJECTIVE: The role of the cerebellum in the pathogenesis of seizures remains controversial.
  • Cerebellar origin of seizures, albeit rare, has been described in the literature in association with intrinsic lesions of the cerebellum.
  • We present a unique case of a patient with medically intractable, secondary generalized epilepsy, associated with a superior cerebellar quadrigeminal arachnoid cyst.
  • On the magnetic resonance imaging (MRI) of the head, he was noticed to have a small superior cerebellar arachnoid cyst in the quadrigeminal area that had increased in size slightly.
  • Intraoperative electrocorticography (ECOG) demonstrated epileptic activity from the cerebellar tissue adjacent to the cyst.
  • CONCLUSION: This case provides strong evidence that, albeit rare, the cerebellum may be a source of epileptic activity due to compression by a lesion in the posterior fossa.
  • The finding of a posterior fossa lesion in such cases, even if it is small and appears benign, should precipitate a discussion about the possible relationship between the posterior fossa lesion and the epilepsy.
  • [MeSH-major] Arachnoid Cysts / diagnosis. Cerebellar Neoplasms / diagnosis. Epilepsy / diagnosis

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  • (PMID = 17680249.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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23. Aksu G, Ulutin C, Fayda M, Saynak M: Cerebellar and multiple spinal hemangioblastomas and intraventricular meningioma managed with subtotal resection and external beam radiotherapy; report of a case with literature review. J BUON; 2005 Jul-Sep;10(3):405-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar and multiple spinal hemangioblastomas and intraventricular meningioma managed with subtotal resection and external beam radiotherapy; report of a case with literature review.
  • Hemangioblastomas are cystic, highly vascular benign neoplasms that constitute 1.5-2.5% of all intracranial tumors and 7-10% of primary posterior fossa tumors.
  • Our patient was a 21-year-old male who presented with cerebellar and multiple spinal hemangioblastomas, and intraventricular meningioma.
  • Intracranial and spinal lesions were treated with external beam radiotherapy following subtotal excision of the cerebellar lesion.
  • However, since hemangioblastoma is a highly vascular tumor and local invasion of critical structures is frequent and multifocality is often a characteristic of the hemangioblastomas that are associated with VHL disease, subtotal excision is frequent and adjuvant therapies such as external beam radiotherapy or stereotactic radiosurgery represent a reasonable treatment in such cases.

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  • (PMID = 17357198.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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24. Jalali R, Mallick I, Dutta D, Goswami S, Gupta T, Munshi A, Deshpande D, Sarin R: Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):974-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy.
  • PURPOSE: To present the effect of radiotherapy doses to different volumes of normal structures on neurocognitive outcomes in young patients with benign and low-grade brain tumors treated prospectively with stereotactic conformal radiotherapy (SCRT).
  • METHODS AND MATERIALS: Twenty-eight patients (median age, 13 years) with residual/progressive brain tumors (10 craniopharyngioma, 8 cerebellar astrocytoma, 6 optic pathway glioma and 4 cerebral low-grade glioma) were treated with SCRT to a dose of 54 Gy in 30 fractions over 6 weeks.
  • [MeSH-major] Brain Neoplasms / radiotherapy. Cognition Disorders / etiology. Glioma / radiotherapy. Intelligence / radiation effects
  • [MeSH-minor] Adolescent. Astrocytoma / radiotherapy. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Cognition / radiation effects. Craniopharyngioma / psychology. Craniopharyngioma / radiotherapy. Female. Humans. Male. Optic Nerve Glioma / radiotherapy. Prospective Studies. Radiotherapy, Conformal / methods. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19864079.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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25. Rasmussen A, Nava-Salazar S, Yescas P, Alonso E, Revuelta R, Ortiz I, Canizales-Quinteros S, Tusié-Luna MT, López-López M: Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma. J Neurosurg; 2006 Mar;104(3):389-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma.
  • OBJECT: Central nervous system (CNS) hemangioblastomas are benign vascular tumors arising either sporadically or as a manifestation of von Hippel-Lindau (VHL) disease, a hereditary cancer syndrome.
  • The authors studied a series of patients with CNS hemangioblastomas and their families to identify germline mutations in the VHL tumor suppressor gene and to establish a predictive testing and screening protocol.
  • All asymptomatic mutation carriers underwent genetic counseling and tumor surveillance.
  • [MeSH-minor] Adolescent. Adult. Cerebellar Neoplasms. Child. Child, Preschool. DNA Mutational Analysis. Female. Genetic Testing. Humans. Male. Mexico. Middle Aged. Pedigree. Prognosis

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  • (PMID = 16572651.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Tamura K, Aoyagi M, Wakimoto H, Tamaki M, Yamamoto K, Yamamoto M, Ohno K: Malignant transformation eight years after removal of a benign epidermoid cyst: a case report. J Neurooncol; 2006 Aug;79(1):67-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant transformation eight years after removal of a benign epidermoid cyst: a case report.
  • Malignant transformation of benign epidermoid cysts is rare and their prognosis remains poor.
  • She had undergone removal of a benign epidermoid cyst in the cerebellopontine angle 8 years previously.
  • The tumor shrank rapidly for 2 months after radiosurgery, but recurred 9 months later.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Epidermal Cyst / pathology
  • [MeSH-minor] Female. Gadolinium. Humans. Image Enhancement. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Radiosurgery

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  • (PMID = 16583265.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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27. Capovilla M, Kambouchner M, Bernier M, Soulier A, Tissier F, Saintigny P: Late cerebellar relapse of a juvenile bronchial carcinoid. Clin Lung Cancer; 2007 Mar;8(5):339-41
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  • [Title] Late cerebellar relapse of a juvenile bronchial carcinoid.
  • Although epithelial bronchial neoplasm is a cancer frequently observed in adult patients, it is rarely observed in patients who are children.
  • The most frequent histologic subtype is well differentiated neuroendocrine tumor, or carcinoid.
  • They have a variable biologic behavior, ranging from benign to malignant tumors capable of very late recurrence or metastasis.
  • We report the case of a child with a pulmonary carcinoid initially considered typical, who presented with relapse in the cerebellum and mediastinum 16 years later.
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoid Tumor / pathology. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / secondary. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / secondary

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  • (PMID = 17562235.001).
  • [ISSN] 1525-7304
  • [Journal-full-title] Clinical lung cancer
  • [ISO-abbreviation] Clin Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Tripathy K, Gouda KP, Das R, Rath J, Mohanty R: Cerebellar haemangioblastoma mimicking renal cell carcinoma--a case report. Indian J Pathol Microbiol; 2005 Jul;48(3):375-6
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  • [Title] Cerebellar haemangioblastoma mimicking renal cell carcinoma--a case report.
  • Haemangioblastoma is a rare benign vascular tumor commonly seen in the cerebellum.
  • Histology revealed a highly vascular tumor composed of clear cells in a lobular arrangement.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis
  • [MeSH-minor] Adult. Cerebellum / pathology. Diagnosis, Differential. Humans. Male

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  • (PMID = 16761758.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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29. Uro-Coste E, Ssi-Yan-Kai G, Guilbeau-Frugier C, Boetto S, Bertozzi AI, Sevely A, Lolmede K, Delisle MB: Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation. J Neurooncol; 2010 May;98(1):143-9
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  • [Title] Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation.
  • Magnetic resonance imaging showed a temporal tumor with prepontine and interpeduncular extension, and two other distinct localizations in cisterna magna and left cerebellar hemisphere.
  • When the tumor is large, multilobular involvement is common, but multiple location of DIG is, on the contrary, very rare.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology

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  • (PMID = 20012157.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Muscarella LA, Barbano R, Augello B, Formica V, Micale L, Zelante L, D'Agruma L, Merla G: An 11-bp duplication in the promoter region of the VHL gene in a patient with cerebellar hemangioblastoma and renal oncocytoma. J Hum Genet; 2007;52(6):485-91
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  • [Title] An 11-bp duplication in the promoter region of the VHL gene in a patient with cerebellar hemangioblastoma and renal oncocytoma.
  • Central nervous system hemangioblastomas are benign vascular tumours that may present sporadically or as manifestation of the von Hippel-Lindau (VHL) disease.
  • VHL Syndrome is a rare autosomal dominant disorder characterized, besides hemangioblastomas, by susceptibility to multifocal and bilateral renal cell carcinoma and cysts, retinal angiomas, pheochromocytoma, epididymis cystoadenoma, pancreatic cysts and/or islet cell tumours.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Cerebellar Neoplasms / genetics. Hemangioblastoma / genetics. Kidney Neoplasms / genetics. Promoter Regions, Genetic. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics


31. Imanaka M, Iida K, Takahashi K, Tsuji K, Nishizawa H, Fukuoka H, Takeno R, Takahashi Y, Okimura Y, Kaji H, Chihara K: The N131S mutation in the von Hippel-Lindau gene in a Japanese family with pheochromocytoma and hemangioblastomas. Endocr J; 2006 Dec;53(6):819-27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • von Hippel-Lindau (VHL) disease (VHLD) is a hereditary autosomal dominant syndrome that causes various benign and malignant tumors.
  • VHLD is caused by mutations in the VHL tumor suppressor gene.
  • We also identified somatic loss of heterozygosity (LOH) at chromosome 3p25-26 in the adrenal tumor of the patient.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Cerebellar Neoplasms / genetics. Hemangioblastoma / genetics. Mutation. Pheochromocytoma / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 17001110.001).
  • [ISSN] 0918-8959
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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32. Ardeleanu C, Dănăilă L, Arsene D: Paraganglioma of the cerebellopontine angle. Case presentation and pathological considerations. Rom J Morphol Embryol; 2005;46(3):171-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They are benign but locally aggressive tumors, causing bone destruction and compression related symptoms.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Paraganglioma / pathology
  • [MeSH-minor] Cerebellum / pathology. Child. Glial Fibrillary Acidic Protein / analysis. Humans. Ki-67 Antigen / analysis. Male

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  • (PMID = 16444300.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen
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33. Gelabert González M: [Posterior fossa hemangioblastomas]. Neurologia; 2007 Dec;22(10):853-9
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  • INTRODUCTION: Hemangioblastomas are histologically benign lesions that comprise 1-2 % of primary nervous system tumours and 8-12 % of all posterior fossa lesions in the adult.
  • Tumors were located on cerebellar hemisphere (17), cerebellar vermis (4) and brain stem (1).
  • Total tumor removal was achieved in 21 patients (95 %), and incomplete removal in 1 cases.
  • CONCLUSIONS: Hemangioblastomas are benign tumors of uncertain origin that are located predominantly in the posterior cranial fossa and the spinal cord.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis. Magnetic Resonance Imaging

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  • (PMID = 17671853.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] Spain
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34. Layadi F, Aniba K, Lmejjati M, Aït Elqadi A, Aït Benali S: [Giant osteoid osteoma of the posterior skull base. A case report and literature review]. Neurochirurgie; 2006 Jun;52(2-3 Pt 1):128-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Ostéome ostéoïde géant de l'étage postérieur de la base du crâne. A propos d'un cas et revue de la littérature.
  • BACKGROUND: Osteoid osteoma is a benign bone neoplasm which is seen in the long bones.
  • He presented with clinical sign of raised intracranial pressure, cerebellar symptoms and large left retro-auricular swelling.
  • CONCLUSION: Although benign and rare, osteoid osteoma can present with neurological deficit due to mass effect and involvement of nervous structures especially in the posterior skull base.
  • [MeSH-major] Osteoma / surgery. Skull Base Neoplasms / surgery

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  • (PMID = 16840973.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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35. Surash S, Ismail A, Loughrey C, van Hille P: Malignant transformation of a neurenteric cyst in the posterior fossa following complete excision. Br J Neurosurg; 2009 Aug;23(4):458-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histologically the original lesion was a benign neurenteric cyst, whereas the recurrent lesion showed a well differentiated adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Cerebellar Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Neural Tube Defects / pathology

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  • (PMID = 19637023.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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36. Okoromah CN, Adegbola TA, Ojuola OI: Neurofibromatosis with malignant transformation presenting as an emergency in a nigerian child: a case report. Niger Postgrad Med J; 2005 Mar;12(1):49-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Neurofibromatosis is a rare disease, and malignant transformation of this otherwise benign tumor is extremely rare in childhood.
  • [MeSH-minor] Cerebellar Neoplasms / secondary. Child. Fatal Outcome. Female. Humans. Kidney Neoplasms / secondary. Lung Neoplasms / secondary. Mediastinal Neoplasms / secondary

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  • (PMID = 15827598.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Nigeria
  • [Number-of-references] 15
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37. Lew SM, Morgan JN, Psaty E, Lefton DR, Allen JC, Abbott R: Cumulative incidence of radiation-induced cavernomas in long-term survivors of medulloblastoma. J Neurosurg; 2006 Feb;104(2 Suppl):103-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The sites of occurrence were cerebral (20 cases) and cerebellar (six cases).
  • Most of these lesions follow a benign course and do not require intervention.
  • [MeSH-major] Cerebellar Neoplasms / radiotherapy. Hemangioma, Cavernous / etiology. Medulloblastoma / radiotherapy. Radiation Injuries

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  • (PMID = 16506497.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Barajas RF Jr, Chi J, Guo L, Barbaro N: Microvascular decompression in hemifacial spasm resulting from a cerebellopontine angle lipoma: case report. Neurosurgery; 2008 Oct;63(4):E815-6; discussion E816
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe a patient with left-sided hemifacial spasm caused by vascular compression of the facial and vestibulocochlear cranial nerves by the anteroinferior cerebellar artery embedded within a cerebellopontine angle lipoma.
  • Magnetic resonance imaging revealed characteristic abnormal signal within the cerebellopontine angle cistern that was consistent with lipoma abutting the anteroinferior cerebellar artery.
  • The offending anteroinferior cerebellar artery branch was dissected away from the VIIth and VIIIth cranial nerves.
  • CONCLUSION: This case demonstrates that relief of the vascular compression, when present, of the VIIth cranial nerve is sufficient for resolution of hemifacial spasm symptoms, even when associated with nearby, benign lesions.
  • [MeSH-major] Cerebellar Neoplasms / complications. Cerebellopontine Angle / pathology. Decompression, Surgical / methods. Hemifacial Spasm / etiology. Lipoma / complications. Vascular Surgical Procedures / methods

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  • (PMID = 18981850.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / TL1 RR024129-01
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-84-0 / Polytetrafluoroethylene
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39. Omeis I, Hillard VH, Braun A, Benzil DL, Murali R, Harter DH: Meningioangiomatosis associated with neurofibromatosis: report of 2 cases in a single family and review of the literature. Surg Neurol; 2006 Jun;65(6):595-603
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Meningioangiomatosis (MA) is a rare benign disorder.
  • We now report 2 additional cases of MA associated with neurofibromatosis 2 (NF2) in a single family, with one occurring in the cerebellum.
  • A small portion of normal-appearing cerebellar cortex was resected to avoid undue retraction.
  • We now report 2 cases of MA associated with NF2 in one family, and we add the cerebellum to possible locations of occurrence.
  • [MeSH-major] Cerebellar Neoplasms / complications. Meningeal Neoplasms / complications. Meningeal Neoplasms / pathology. Meningioma / complications. Meningioma / pathology. Neurofibromatosis 2 / complications

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  • (PMID = 16720184.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 75
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40. Furtado SV, Venkatesh PK, Dadlani R, Reddy K, Hegde AS: Adult medulloblastoma and the "dural-tail" sign: rare mimic of a posterior petrous meningioma. Clin Neurol Neurosurg; 2009 Jul;111(6):540-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We review literature of this atypical presentation of medulloblastoma and "dural-tail" sign, which can be associated with other benign or malignant lesions.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Dura Mater / pathology. Infratentorial Neoplasms / pathology. Medulloblastoma / pathology. Meningioma / pathology

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  • (PMID = 19285790.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 19
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41. Gezen F, Karatas A, Is M, Yildirim U, Aytekin H: Giant cavernous haemangioma in an infant. Br J Neurosurg; 2008 Dec;22(6):787-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cavernous haemangiomas are benign vascular lesions of the central nervous system.
  • [MeSH-major] Cerebellar Neoplasms / complications. Hemangioma, Cavernous, Central Nervous System / complications. Seizures / etiology

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  • (PMID = 18686064.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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42. Zúccaro G, Sosa F: Cerebellopontine angle lesions in children. Childs Nerv Syst; 2007 Feb;23(2):177-83

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign lesions are more frequent.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery

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  • (PMID = 17072661.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
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43. Arkadopoulos N, Karapanos K, Stafyla V, Yiallourou A, Koureas A, Kondi-Pafiti A, Smyrniotis V: Combination of right nephrectomy and total pancreaticoduodenectomy for Von Hippel-Lindau disease. JOP; 2010;11(3):270-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Von Hippel-Lindau disease is an inherited syndrome of multiorgan neoplasia caused by a germline mutation in the von Hippel-Lindau gene and can include central nervous system tumors, renal cell carcinomas and benign pancreatic cystic tumors.
  • CASE REPORT: We report the case of a 56-year-old patient who had a past history of cerebellar hemangioblastoma and presented with abdominal pain.
  • [MeSH-major] Carcinoma, Renal Cell / surgery. Neoplasms, Multiple Primary / surgery. Nephrectomy / methods. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods. von Hippel-Lindau Disease / surgery

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  • (PMID = 20442526.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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44. Stein PJ: A case of cerebellopontine angle meningioma presenting with neck and upper extremity pain. J Manipulative Physiol Ther; 2009 Nov-Dec;32(9):776-80
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  • INTERVENTION AND OUTCOME: Magnetic resonance imaging studies of the neck and brain revealed a posterior fossa tumor, which was eventually diagnosed as a benign meningioma.
  • Partial surgical removal of the tumor mass was followed by radiation therapy.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / radiography. Cerebellopontine Angle / pathology. Cerebellopontine Angle / radiography. Meningioma / pathology. Meningioma / radiography. Neck / physiopathology. Pain / etiology. Pain / physiopathology. Upper Extremity / physiopathology

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  • (PMID = 20004806.001).
  • [ISSN] 1532-6586
  • [Journal-full-title] Journal of manipulative and physiological therapeutics
  • [ISO-abbreviation] J Manipulative Physiol Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Pascual-Castroviejo I, Pascual-Pascual SI, Viaño J, Carceller F, Gutierrez-Molina M, Morales C, Frutos-Martinez R: Posterior fossa tumors in children with neurofibromatosis type 1 (NF1). Childs Nerv Syst; 2010 Nov;26(11):1599-603
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  • Four of them had astrocytomas but only in one case was the tumour primarily cerebellar while the tumour was primarily of the brain stem with invasion of the adjacent regions of one or both cerebellar hemispheres in three patients.
  • The patient with primary cerebellar astrocytoma is apparently cured 7 years after the removal of the tumour.
  • The patients with the brain stem tumours extending to the cerebellum, showed a chronic slowly progressive cerebellar disease, but remain alive at age of more than 20 years (one was lost to follow-up).
  • Most of these tumours are histologically benign (low grade astrocytomas).
  • [MeSH-major] Cranial Fossa, Posterior. Neurofibromatosis 1 / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / diagnosis. Astrocytoma / mortality. Astrocytoma / pathology. Astrocytoma / surgery. Brain Stem Neoplasms / diagnosis. Brain Stem Neoplasms / mortality. Brain Stem Neoplasms / pathology. Brain Stem Neoplasms / surgery. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / mortality. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Male. Medulloblastoma / diagnosis. Medulloblastoma / mortality. Medulloblastoma / pathology. Medulloblastoma / surgery. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed. Young Adult

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  • [CommentIn] Childs Nerv Syst. 2010 Nov;26(11):1491; author reply 1493 [20853110.001]
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  • (PMID = 20464401.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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46. Isobe N, Oki S, Murakami T, Ooyama S, Kureshima M, Kurokawa Y: [A case of atypical meningioma with Lhermitte-Duclos disease]. No Shinkei Geka; 2005 Dec;33(12):1229-35
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  • Lhermitte-Duclos disease is known as an uncommon disease that characterized by a slowly progressive tumor of the cerebellar hemisphere.
  • CT scan on arrival showed a large mass of the left frontal region and slightly high-density linear lesion in the right cerebellar hemisphere.
  • MRI also revealed well-enhanced mass in the left frontal region and parallel linear striation in the right cerebellar hemisphere.
  • But, the patient had neither cerebellar dysfunction nor signs of increased intracranial pressure.
  • The patient had angioma of the left breast and bilateral benign struma, no typical manifestation of Cowden syndrome.
  • Removal of the frontal tumor caused the convulsion was subsequently performed.
  • After the operation, radiation therapy was not done because of the total removal of tumor and intension on patient side.
  • However, we should continuously take account to not only the recurrence of meningioma but also the enlargement of the cerebellar lesion and the complication of malignant tumors in whole body.
  • [MeSH-major] Cerebellar Neoplasms / complications. Ganglioneuroma / complications. Meningeal Neoplasms / complications. Meningioma / complications
  • [MeSH-minor] Cerebellum / pathology. Diffusion Magnetic Resonance Imaging. Female. Humans. Middle Aged. Neuronavigation. Neurosurgical Procedures / methods

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  • (PMID = 16359035.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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47. Stüer C, Vilz B, Majores M, Becker A, Schramm J, Simon M: Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer; 2007 Dec 15;110(12):2799-808
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  • BACKGROUND: Most pilocytic astrocytomas (piloA) are benign growths (World Health Organization [WHO] grade 1) of the deep midline structures, the brainstem, and the cerebellum.
  • RESULTS: There were 20 patients (45%) with supratentorial lobar piloA (including 10 temporal/temporomesial tumors, 5 parietal tumors, 3 insular tumors, 1 frontal tumor, and 1 occipital tumors), 12 patients with cerebellar piloA, 7 patients with brainstem piloA, 2 patients with opticochiasmatic PiloA, 1 patient with intramedullary piloA, and 2 patients with piloA of the basal ganglia.
  • All but 1 patient with a lobar tumor presented with epilepsy.
  • Tumor recurrence or disease progression was observed in 13 of 44 patients (30%).
  • CONCLUSIONS: PiloA in adult patients, surprisingly, often was not a benign disease.
  • [MeSH-major] Astrocytoma / pathology. Astrocytoma / radiography. Brain Neoplasms / pathology

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  • [CommentIn] Nat Clin Pract Neurol. 2008 Jun;4(6):296-7 [18414467.001]
  • (PMID = 17973253.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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48. Opocher G, Schiavi F, Iacobone M, Toniato A, Sattarova S, Erlic Z, Martella M, Mian C, Merante Boschin I, Zambonin L, De Lazzari P, Murgia A, Pelizzo MR, Favia G, Mantero F: Familial nonsyndromic pheochromocytoma. Ann N Y Acad Sci; 2006 Aug;1073:149-55
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  • The proband of family 2 is a female who had a 5-cm benign adrenal pheochromocytoma at the age of 34 years, while her cousin (maternal branch) had a monolateral pheochromocytoma at the age of 42 years.
  • Her brother had a monolateral benign pheochromocytoma.
  • The proband had no cerebellar or spinal NMR findings or retinal alterations.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Pheochromocytoma / genetics
  • [MeSH-minor] Genetic Predisposition to Disease. Humans. Proto-Oncogene Proteins c-ret / genetics. Succinate Dehydrogenase / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 17102081.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.3.99.1 / Succinate Dehydrogenase; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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49. Saint-Blancard P, Goasguen O, Kossowski M, Dulou R: [A rare primary tumor of the cerebellopontine angle: melanotic schwannoma, a pigmented tumor with unpredictable prognosis]. Rev Med Interne; 2008 Jul;29(7):587-90
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  • [Title] [A rare primary tumor of the cerebellopontine angle: melanotic schwannoma, a pigmented tumor with unpredictable prognosis].
  • Schwannomas are common ubiquitous benign tumours of the nervous sheaths.
  • We report a case of melanotic schwannoma of the cerebellopontine angle in a 52-year-old man with a slowly progressive cerebellar syndrome since 1978, who presented with a posterior cerebral fossa bleeding.

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  • (PMID = 18276040.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Melanins
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50. Muzumdar D, Ventureyra EC: Tonsillar herniation and cervical syringomyelia in association with posterior fossa tumors in children: a case-based update. Childs Nerv Syst; 2006 May;22(5):454-9
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  • The symptomatology is predominantly directed towards the tumor.
  • CASE REPORT: We describe a case of a pilocytic astrocytoma of the cerebellum in a 13-year-old girl who presented with clinical features of progressively worsening raised intracranial pressure and secondary tonsillar herniation and cervical syringomyelia.
  • Magnetic resonance (MR) imaging showed a large midline inhomogenously enhancing vermian tumor causing moderate obstructive hydrocephalus.
  • In addition, the cerebellar tonsils herniated down to the C2 level, and there was a centrally located syrinx from C2-T1.
  • The tumor was resected through a suboccipital craniectomy.
  • CONCLUSIONS: The occurrence of tonsillar herniation and syringomyelia in association with a slow growing benign tumor like pilocytic astrocytoma of the cerebellum is uncommon.
  • Surgical extirpation of the tumor restores the normal cerebrospinal fluid circulation at the foramen magnum and produces an excellent outcome.
  • [MeSH-major] Astrocytoma. Hernia / etiology. Infratentorial Neoplasms / complications. Palatine Tonsil / pathology. Syringomyelia / etiology

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  • (PMID = 16397818.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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51. Gomy I, Molfetta GA, de Andrade Barreto E, Ferreira CA, Zanette DL, Casali-da-Rocha JC, Silva WA Jr: Clinical and molecular characterization of Brazilian families with von Hippel-Lindau disease: a need for delineating genotype-phenotype correlation. Fam Cancer; 2010 Dec;9(4):635-42
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  • von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary cancer syndrome that predisposes to the development of a variety of benign and malignant tumours, especially cerebellar haemangioblastomas, retinal angiomas and clear-cell renal cell carcinomas (RCC).
  • Eighteen of twenty patients from ten unrelated families underwent genetic testing, nine of them fulfilled VHL disease criteria and one had an apparently sporadic cerebellar haemangioblastoma.
  • [MeSH-major] Carcinoma, Renal Cell / genetics. Gene Deletion. Kidney Neoplasms / genetics. Mutation / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics
  • [MeSH-minor] Adolescent. Adult. Brazil. Case-Control Studies. Cerebellar Neoplasms / complications. Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / pathology. Child. DNA Mutational Analysis. DNA, Neoplasm / genetics. Family. Female. Genetic Association Studies. Genetic Predisposition to Disease. Genotype. Humans. Introns. Male. Pedigree. Polymerase Chain Reaction. Polymorphism, Restriction Fragment Length. Risk Factors. Young Adult

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  • (PMID = 20567917.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Neoplasm; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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52. Tchoghandjian A, Fernandez C, Colin C, El Ayachi I, Voutsinos-Porche B, Fina F, Scavarda D, Piercecchi-Marti MD, Intagliata D, Ouafik L, Fraslon-Vanhulle C, Figarella-Branger D: Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature. Brain; 2009 Jun;132(Pt 6):1523-35
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  • These tumours affect preferentially the cerebellum (benign clinical course) and the optic pathway, especially the hypothalamo-chiasmatic region (poor prognosis).
  • We used the microarray technique to compare the transcriptional profiles of five hypothalamo-chiasmatic and six cerebellar pilocytic astrocytomas.
  • Results demonstrate that cerebellar and hypothalamo-chiasmatic pilocytic astrocytomas are two genetically distinct and topography-dependent entities.
  • [MeSH-major] Astrocytoma / diagnosis. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Astrocytes / metabolism. Cell Proliferation. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / pathology. Child. Child, Preschool. DNA, Neoplasm / genetics. Diagnosis, Differential. Gene Expression Profiling / methods. Gene Expression Regulation, Neoplastic. Humans. Hypothalamus / metabolism. Infant. Middle Aged. Neoplastic Stem Cells / pathology. Neuroglia / pathology. Oligonucleotide Array Sequence Analysis / methods. Optic Chiasm / cytology. Optic Chiasm / embryology. Optic Chiasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction / methods. Up-Regulation. Vimentin / metabolism. Young Adult

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  • (PMID = 19336457.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Vimentin
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53. Thines L, Lejeune JP, Ruchoux MM, Assaker R: Management of delayed intracranial and intraspinal metastases of intradural spinal paragangliomas. Acta Neurochir (Wien); 2006 Jan;148(1):63-6; discussion 66
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  • However intradural spinal paragangliomas are commonly described and are considered as benign entities.
  • Seven years after the first operation, a cystic cerebellar lesion was successfully treated by surgery.
  • [MeSH-major] Brain Neoplasms / secondary. Lumbar Vertebrae. Paraganglioma / secondary. Spinal Cord Neoplasms / pathology. Spinal Neoplasms / secondary. Thoracic Vertebrae

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  • (PMID = 16283104.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 14
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54. Dutta D, Vanere P, Gupta T, Munshi A, Jalali R: Factors influencing activities of daily living using FIM-FAM scoring system before starting adjuvant treatment in patients with brain tumors: results from a prospective study. J Neurooncol; 2009 Aug;94(1):103-10
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  • BACKGROUND: Patients with brain tumors have varied degree of functional and psychological impairments because of factors relating to the tumor or to the treatment they receive.
  • MATERIAL AND METHOD: From August 2007 to April 2008, 150 consecutive adult (>18 years) primary brain tumor patients (median age 40 years; male 88, female 62) registered in a general out-patient neuro-oncology clinic were accrued and detailed data were recorded.
  • Seventy percent had malignant tumor (66% high-grade and 34% low-grade; 70% intra-axial).
  • Univariate analysis showed total FIM-FAM scores not significantly different with age (< or =35 years vs. >35 years; P = 0.994), sex (male versus female; P = 0.133), and grade of the tumor (high-grade versus low-grade; P = 0.142) but were significantly higher in patients with a Karnofsky performance score (KPS) of > or =70 as compared with <70 (P = 0.001), neurological performance scale (NPS) of 0 or 1 vs. 2 or 3; P = 0.001), disease type (benign versus malignant; P = 0.001), and site of disease (cerebral versus cerebellar; P = 0.024).
  • A trend for correlation between tumor sites with the corresponding function as assesses on the FIM-FAM score was observed.
  • There is strong correlation with age, type of tumor, and site of disease with different functional and cognitive domain impairment.
  • [MeSH-major] Activities of Daily Living / psychology. Brain Neoplasms / psychology. Disability Evaluation. Stress, Psychological / psychology

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  • (PMID = 19255726.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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55. Pascual Castroviejo I, Pascual Pascual S, Velázquez Fragua R, Viaño J, Garcia Segura JM: [Brain stem tumors associated with neurofibromatosis type 1. Presentation of 20 infantile patients]. Neurologia; 2007 Dec;22(10):846-52
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  • Thirteen of the 20 patients (65 %) also had optic pathway tumor.
  • Brain stem tumor identification occurred at the same time as NF1 in the patients who were studied by MR at the time of the first consult.
  • Diffuse or localized medullary enlargement was the most frequent MR imaging and appeared in 13 patients (65%), followed by the tumor that involved all brain stem (pontine and medullary areas) that appeared in 6 patients (30 %).
  • In the last group, one tumor showed extension through brain stem and medial cerebellar parts, another was located in the aqueduct and in the periaqueductal areas and showed slow progressive growth, and one third patient had a tumor with aggressive signs in the SMR study.
  • Another patient had an aggressive tumor that involved the left optic nerve, chiasm, mesencephalon and upper right pontine areas.
  • The histological study of the tumoral biopsic tissue of the two last patients showed astrocitoma degree 1 (benign tumor).
  • Only one of the 20 patients died, although it was due to a malignant chiasmatic tumor, that had been treated twenty years before, and not by the brain stem tumor.
  • MR and SMR are necessary to a correct identification of the tumor in some patients.
  • Most of these tumors are benign.
  • [MeSH-major] Brain Neoplasms / complications. Brain Neoplasms / diagnosis. Brain Stem. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Neurofibromatosis 1 / complications


56. Koch HJ, Roeber S, Zimmermann UW, Schäfer C, Villarrubia V, Kuchelmeister K, Schachenmayr W, Bogdahn U, Steinbrecher A: [Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle]. Wien Med Wochenschr; 2005 Aug;155(15-16):360-4
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  • Meningeal melanocytoma refers to the uncommon clinical appearance of a generally benign tumour deriving from leptomeningeal melanocytes.
  • This tumor did not respond to a combined radiochemotherapy including oral temozolomide, and the patient died 5 months after starting treatment for this relapse.
  • [MeSH-major] Cerebellopontine Angle. Melanocytes / pathology. Melanoma. Meningeal Neoplasms. Meninges. Neoplasm Seeding
  • [MeSH-minor] Administration, Oral. Adult. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / therapeutic use. Arachnoid. Cerebellar Diseases / diagnosis. Cerebellar Neoplasms / diagnosis. Combined Modality Therapy. Dacarbazine / analogs & derivatives. Dacarbazine / therapeutic use. Diagnosis, Differential. Disease Progression. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Pia Mater. Radiotherapy Dosage. Time Factors

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  • (PMID = 16160923.001).
  • [ISSN] 0043-5341
  • [Journal-full-title] Wiener medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Wien Med Wochenschr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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57. Chen L, Zhao Y, Chen Z, Tee M, Mao Y, Zhou LF: Multiple dynamic cavernous malformations in a girl: long-term follow-up. Surg Neurol; 2009 Dec;72(6):728-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Cavernous malformations have generally been viewed as fairly benign vascular lesions with low potential for causing massive hemorrhage.
  • [MeSH-major] Cerebral Hemorrhage / surgery. Hemangioma, Cavernous, Central Nervous System / surgery. Neoplasm Recurrence, Local / surgery. Neoplasms, Multiple Primary / surgery
  • [MeSH-minor] Angiography, Digital Subtraction. Calcinosis / diagnosis. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Child. Child, Preschool. Dominance, Cerebral / physiology. Female. Follow-Up Studies. Frontal Lobe / pathology. Frontal Lobe / surgery. Gait Ataxia / diagnosis. Humans. Infant. Magnetic Resonance Imaging. Neurologic Examination. Neuronavigation. Occipital Lobe / pathology. Occipital Lobe / surgery. Parietal Lobe / pathology. Parietal Lobe / surgery. Postoperative Complications / diagnosis. Reoperation. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • (PMID = 19604555.001).
  • [ISSN] 1879-3339
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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58. Happle C, Wetzke M, Hermann EJ, Krauss JK, Hartmann H, Lücke T: ['Cases against KiSS': a diagnostic algorithm for children with torticollis]. Klin Padiatr; 2009 Dec;221(7):430-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Whereas most cases are benign, there is a long list of serious differential diagnoses for torticollis in infants.
  • [MeSH-major] Algorithms. Astrocytoma / diagnosis. Cerebellar Neoplasms / diagnosis. Cervical Vertebrae. Ganglioglioma / diagnosis. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Spinal Diseases / diagnosis. Torticollis / etiology
  • [MeSH-minor] Child, Preschool. Diagnostic Errors. Gait Disorders, Neurologic / etiology. Humans. Infant. Male. Microsurgery. Neoplasm, Residual / diagnosis. Neurologic Examination. Postoperative Complications / diagnosis. Reoperation. Syndrome

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20013566.001).
  • [ISSN] 1439-3824
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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59. Suyama K, Ujifuku K, Hirao T, Takahata H, Ito M, Yonekura M, Nagata I: Symptomatic syringomyelia associated with a dermoid tumor in the posterior fossa. Neurol Med Chir (Tokyo); 2009 Sep;49(9):434-7
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  • [Title] Symptomatic syringomyelia associated with a dermoid tumor in the posterior fossa.
  • A 28-year-old female presented with a dermoid tumor in the posterior fossa associated with symptomatic syringomyelia.
  • Magnetic resonance (MR) imaging revealed cervical syringomyelia and tonsillar herniation concomitant with an intradural posterior fossa tumor which was totally removed.
  • The histological diagnosis was dermoid tumor.
  • Her symptoms subsided and MR imaging demonstrated complete resolution of the syrinx 12 months after tumor removal.
  • Benign congenital intracranial tumor may cause tonsillar herniation resulting in symptomatic cervical syringomyelia.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cranial Fossa, Posterior / pathology. Dermoid Cyst / pathology. Infratentorial Neoplasms / pathology. Syringomyelia / etiology

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  • (PMID = 19779293.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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60. Piedra MP, Scheithauer BW, Driscoll CL, Link MJ: Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report. Neurosurgery; 2006 Jul;59(1):E206; discussion E206
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report.
  • OBJECTIVE: The majority of tumors of the cerebellopontine angle (CPA) are benign.
  • A neurological work-up revealed a large tumor in the left CPA radiographically diagnosed as a vestibular schwannoma.
  • INTERVENTION: A translabyrinthine approach revealed a pigmented, vascular neoplasm encasing vessels and cranial nerves of the left CPA.
  • The tumor was subtotally resected, and a histopathological diagnosis of melanoma was made.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebellopontine Angle. Melanocytes / pathology. Melanoma / diagnosis. Neuroma, Acoustic / diagnosis

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  • (PMID = 16823290.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. Broekman ML, Risselada R, Engelen-Lee J, Spliet WG, Verweij BH: Glioblastoma multiforme in the posterior cranial fossa in a patient with neurofibromatosis type I. Case Rep Med; 2009;2009:757898

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with Neurofibromatosis type 1 (NF1) have an increased risk of developing neoplasms.
  • The most common brain tumors, found in 15%-20% of NF1 patients, are hypothalamic-optic gliomas, followed by brainstem and cerebellar pilocytic astrocytomas.
  • These tumors generally have a benign nature.

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  • (PMID = 20029672.001).
  • [ISSN] 1687-9635
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2796235
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62. Ali Y, Rahme R, Moussa R, Abadjian G, Menassa-Moussa L, Samaha E: Multifocal meningeal melanocytoma: a new pathological entity or the result of leptomeningeal seeding? J Neurosurg; 2009 Sep;111(3):488-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Meningeal melanocytoma is a rare benign CNS tumor derived from the leptomeningeal melanocytes.
  • The authors report a unique case of multifocal benign meningeal melanocytoma involving both cerebellopontine angles and the thoracic spinal cord, with associated diffuse leptomeningeal hyperpigmentation.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle. Melanocytes / pathology. Melanoma / pathology. Meningeal Neoplasms / pathology. Neoplasm Seeding. Spinal Cord Neoplasms / pathology

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  • (PMID = 19361258.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Amit A, Achawal S, Dorward N: Pituitary macro adenoma and vestibular schwannoma: a case report of dual intracranial pathologies. Br J Neurosurg; 2008 Oct;22(5):695-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A case of dual intracranial benign tumours comprising pituitary adenoma and vestibular schwannoma is described.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Neoplasms, Multiple Primary / pathology. Neuroma, Acoustic / pathology. Pituitary Neoplasms / pathology

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  • (PMID = 18661423.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 4
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64. Luan S, Zhuang D, Sun L, Huang FP: Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature. Clin Neurol Neurosurg; 2010 May;112(4):362-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature.
  • Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been identified as a novel and distinctive type of primary central nervous system neoplasm.
  • In this report, we present a case with RGNT arising from the right cerebellar hemisphere.
  • RGNT of the fourth ventricle is a rare, benign tumor with an excellent prognosis.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Glioma / pathology. Rosette Formation
  • [MeSH-minor] Adult. Cerebellar Neoplasms / pathology. Cerebellum / pathology. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Treatment Outcome

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  • [Copyright] Crown Copyright 2010. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20133047.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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65. Wu CH, Chai JW, Lee CH, Chen WH, Lee T, Chen CC: Assessment with magnetic resonance imaging and spectroscopy in Lhermitte-Duclos disease. J Chin Med Assoc; 2006 Jul;69(7):338-42
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  • Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterized by distortion of the normal cerebellar laminar cytoarchitecture.
  • We report a 22-year-old man admitted for injury sustained in a traffic accident with the incidental finding of a cerebellar mass.
  • Magnetic resonance imaging (MRI) revealed a mass lesion within the right cerebellar hemisphere.
  • In addition, no disturbance of water diffusion on diffusion-weighted MRI, and associations of decreases in the N-acetylaspartate/creatine (NAA/Cr) and NAA/Choline (Cho) ratios with near normal values of Cho/Cr, as well as an obvious lactate peak gave supplemental information for diagnosis.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellum / pathology. Ganglioneuroma / pathology

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  • (PMID = 16903650.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 30KYC7MIAI / Aspartic Acid; 997-55-7 / N-acetylaspartate; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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66. Pettorini BL, Narducci A, de Carlo A, Abet F, Caldarelli M, Massimi L, Tamburrini G, Di Rocco C: Thyroid neoplasm after central nervous system irradiation for medulloblastoma in childhood: report of two cases. Childs Nerv Syst; 2009 May;25(5):631-4
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  • [Title] Thyroid neoplasm after central nervous system irradiation for medulloblastoma in childhood: report of two cases.
  • Irradiation is the well-known risk factor for development of benign and malignant thyroid tumours.
  • However, only a few papers on radioinduced thyroid neoplasms after CNS irradiation have been published in the literature.
  • We report on two additional cases of thyroid neoplasms following childhood CNS irradiation for the treatment of a posterior fossa medulloblastoma.
  • [MeSH-major] Carcinoma, Papillary / etiology. Cerebellar Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Medulloblastoma / radiotherapy. Neoplasms, Radiation-Induced / etiology. Thyroid Neoplasms / etiology

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  • (PMID = 19225785.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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67. Kondziolka D, Flickinger JC, Lunsford LD: The principles of skull base radiosurgery. Neurosurg Focus; 2008;24(5):E11
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  • Stereotactic radiosurgery is commonly used for selected patients with benign cranial base tumors.
  • The goal of radiosurgery is cessation of tumor growth and preservation of neurological function.
  • [MeSH-major] Cranial Irradiation / methods. Radiosurgery / methods. Skull Base Neoplasms / surgery
  • [MeSH-minor] Brain Stem / physiopathology. Brain Stem / surgery. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / surgery. Cranial Nerve Injuries / prevention & control. Decompression, Surgical. Diagnostic Imaging. Humans. Meningeal Neoplasms / surgery. Meningioma / surgery. Neurilemmoma / surgery. Patient Selection

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  • (PMID = 18447740.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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68. Warren FM, Shelton C, Wiggins RH 3rd, Herrod HC, Harnsberger HR: Imaging characteristics of metastatic lesions to the cerebellopontine angle. Otol Neurotol; 2008 Sep;29(6):835-8
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  • T2 and fluid-attenuated inversion-recovery (FLAIR) imaging shows adjacent cerebellar and brainstem vasogenic edema.
  • Characteristics that differentiate metastatic lesions from benign lesions of the CPA include vasogenic edema on T2 and FLAIR imaging and multiple central nervous system lesions and lesions that are eccentric to the IAC.
  • [MeSH-major] Cerebellar Neoplasms / secondary. Cerebellopontine Angle. Ear, Inner
  • [MeSH-minor] Breast Neoplasms / epidemiology. Breast Neoplasms / pathology. Colonic Neoplasms / epidemiology. Colonic Neoplasms / pathology. Female. Humans. Kidney Neoplasms / epidemiology. Kidney Neoplasms / pathology. Lung Neoplasms / epidemiology. Lung Neoplasms / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology

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  • (PMID = 18636029.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Pascual-Castroviejo I, Pascual-Pascual SI, Velazquez-Fragua R, García-Guereta L, López-Gutiérrez JC, Olivares P, Tovar J: Association of cutaneous red-to-purple hemangiomas with leptomeningeal hemangiomas. a clinical study of two patients. Neuropediatrics; 2010 Feb;41(1):7-11
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  • Cutaneous hemangioma is a benign vascular tumor of infancy with an initial proliferating period that appears between 1 to 2 weeks of life, extends during 18 months to 2 years of life, and then slowly regresses during several years until it disappears completely.
  • These cutaneous anomalies are commonly associated with cerebellar malformations, main cerebral arteries anomalies, congenital cardiac anomalies and/or coarctation of the aorta and persistence of embryonic arteries.
  • [MeSH-major] Hemangioma. Meningeal Neoplasms. Skin Diseases, Vascular. Skin Neoplasms

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  • (PMID = 20571984.001).
  • [ISSN] 1439-1899
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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70. Akcaglar S, Yavascaoglu I, Vuruskan H, Oktay B: Genetic evaluation of von Hippel-Lindau disease for early diagnosis and improved prognosis. Int Urol Nephrol; 2008;40(3):615-20
MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.

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  • von Hippel-Lindau disease (VHL) is a rare autosomal-dominant disorder in which affected individuals develop tumors in a number of locations.
  • Metastatic renal cell carcinoma (RCC) remains the leading cause of mortality in patients with clear cell RCC arising from mutations in the VHL tumor suppressor.
  • VHL patients can present with a number of other renal lesions, such as hemangiomas and benign adenomas, in addition to simple cysts and RCC.
  • Detailed clinical examination of the 22 kindreds with a VHL mutation revealed cerebellar hemangioblastoma (three kindreds), meningioma (two) and renal cell carcinoma (five).
  • [MeSH-major] Carcinoma, Renal Cell / genetics. Kidney Neoplasms / genetics. Mutation. von Hippel-Lindau Disease / genetics

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  • (PMID = 18074239.001).
  • [ISSN] 0301-1623
  • [Journal-full-title] International urology and nephrology
  • [ISO-abbreviation] Int Urol Nephrol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Hungary
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71. Leung RS, Biswas SV, Duncan M, Rankin S: Imaging features of von Hippel-Lindau disease. Radiographics; 2008 Jan-Feb;28(1):65-79; quiz 323
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  • von Hippel-Lindau (VHL) disease is a rare, autosomal dominantly inherited multisystem disorder characterized by development of a variety of benign and malignant tumors.
  • The most common causes of death in VHL disease patients are renal cell carcinoma and neurologic complications from cerebellar hemangioblastomas.
  • [MeSH-major] Diagnostic Imaging / methods. Image Enhancement / methods. Neoplasms / diagnosis. von Hippel-Lindau Disease / diagnosis

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  • (PMID = 18203931.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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72. Huang H, Hara A, Homma T, Yonekawa Y, Ohgaki H: Altered expression of immune defense genes in pilocytic astrocytomas. J Neuropathol Exp Neurol; 2005 Oct;64(10):891-901
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  • Pilocytic astrocytoma (WHO grade I) is a circumscribed, slowly growing, benign astrocytoma that most frequently develops in the cerebellar hemispheres and in midline structures and occurs predominantly in childhood and adolescence.
  • To search for potential molecular mechanisms underlying its benign biologic behavior, we compared gene expression profiles of pilocytic astrocytomas (8 cases) with those of normal cerebellum (4 cases), low-grade astrocytomas (WHO grade II; 15 cases), and oligodendrogliomas (WHO grade II; 17 cases) by cDNA array analysis.
  • A number of immune system-related genes such as HLA-DRalpha, HLA-DPB1, HLA-DQB1, IgG3, IgGK, FCER1G, A2M, FCRN, IFI-56K, and DAP12 were upregulated in pilocytic astrocytomas relative to normal cerebellum, grade II astrocytomas, and oligodendrogliomas.
  • These results suggest that gene expression profiles of pilocytic astrocytomas differ significantly from those of diffusely infiltrating low-grade gliomas and that their benign biologic behavior may be related to upregulation of immune defense-associated genes.
  • [MeSH-major] Astrocytoma / genetics. Astrocytoma / immunology. Brain Neoplasms / genetics. Brain Neoplasms / immunology. Gene Expression. Immunity / genetics
  • [MeSH-minor] Adolescent. Cerebellum / metabolism. Child. Child, Preschool. Cluster Analysis. Computer Systems. Female. Gene Expression Profiling. HLA-DR Antigens / metabolism. Humans. Male. Oligodendroglioma / genetics. Oligodendroglioma / metabolism. Oligonucleotide Array Sequence Analysis. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction


73. Bourguignont A, Blaise P, Janin N, Rakic JM: [Clinical case of the month. A case of von Hippel-Lindau disease]. Rev Med Liege; 2010 Feb;65(2):62-6
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  • [Transliterated title] Le cas clinique du mois. A propos d'un cas de maladie de von Hippel-Lindau.
  • The spectrum of clinical manifestations is broad and includes central nervous system hemangioblastomas and visual benign and malignant tumors.
  • [MeSH-minor] Adult. Cerebellar Neoplasms / pathology. Female. Hemangioblastoma / pathology. Hemangioma, Capillary / pathology. Humans. Magnetic Resonance Imaging. Pancreatic Cyst / pathology. Pedigree. Retinal Neoplasms / pathology

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  • (PMID = 20344914.001).
  • [ISSN] 0370-629X
  • [Journal-full-title] Revue médicale de Liège
  • [ISO-abbreviation] Rev Med Liege
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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74. Sergides IG, Wainwright KL, Biggs M: Incidental hemangioblastoma of the filum terminale. Acta Neurol Belg; 2009 Mar;109(1):55-6
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  • The natural history is unknown but benign as well as more aggressive presentations have been reported.
  • [MeSH-major] Cauda Equina / pathology. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis

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  • (PMID = 19402577.001).
  • [ISSN] 0300-9009
  • [Journal-full-title] Acta neurologica Belgica
  • [ISO-abbreviation] Acta Neurol Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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75. Banka S, Walsh R, Brundler MA: First report of occurrence of choroid plexus papilloma and medulloblastoma in the same patient. Childs Nerv Syst; 2007 May;23(5):587-9
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  • INTRODUCTION: Choroid plexus papilloma is a benign epithelial brain tumour showing a striking predilection for infants and occurring most frequently in the lateral and fourth ventricles.
  • At 8 years of age, she presented with right cerebellar medulloblastoma.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebral Ventricle Neoplasms / pathology. Medulloblastoma / pathology. Papilloma, Choroid Plexus / pathology

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  • (PMID = 17106748.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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76. Vougioukas VI, Gläsker S, Hubbe U, Berlis A, Omran H, Neumann HP, Van Velthoven V: Surgical treatment of hemangioblastomas of the central nervous system in pediatric patients. Childs Nerv Syst; 2006 Sep;22(9):1149-53
MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.

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  • OBJECTIVE: Hemangioblastomas are histologically benign lesions that occur sporadically or as a manifestation of von Hippel-Lindau disease (VHL).
  • The treatment strategy of these neoplasms is complicated by their unpredictable growth patterns and the often irreversible neurological deficits they may cause.
  • RESULTS: Patients with cerebellar and intramedullary hemangioblastomas did not develop additional neurological deficits postoperatively.
  • During the observed follow-up periods, no tumor recurrences were observed.
  • [MeSH-major] Brain Stem Neoplasms / surgery. Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Spinal Cord Neoplasms / surgery. von Hippel-Lindau Disease / surgery
  • [MeSH-minor] Adolescent. Brain Stem / pathology. Brain Stem / surgery. Cerebellum / pathology. Cerebellum / surgery. Child. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Neurologic Examination. Postoperative Complications / diagnosis. Spinal Cord / pathology. Spinal Cord / surgery

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  • (PMID = 16369852.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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77. Tena-Suck M, Collado-Ortiz MA, Rembao-Bojórquez D, Gestista N, García-Marquez A: Coexistence between meningioma and tuberculosis: case report. J Neurooncol; 2010 Sep;99(2):289-94
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  • A 66 year-old female with a history of breast carcinoma at 41 years, treated with radical mastectomy and radio and chemotherapy, and rheumatoid arthritis, treated in the last 10 years, presented two months ago with occipital headache, nausea, cerebellar syndrome, alterations of speech, and memory loss.
  • Histology showed a benign meningioma with many multinuclear giant cells, granulomas, and central caseating necrosis.
  • [MeSH-major] Meningeal Neoplasms / complications. Meningioma / complications. Tuberculosis, Meningeal / complications
  • [MeSH-minor] Aged. Arthritis, Rheumatoid / drug therapy. Breast Neoplasms / pathology. Breast Neoplasms / therapy. Female. Humans. Magnetic Resonance Imaging. Mastectomy, Radical. Mycobacterium tuberculosis / pathogenicity. Tomography, X-Ray Computed

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  • (PMID = 20195701.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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78. Pascual-Castroviejo I, Pascual-Pascual SI, Velazquez-Fragua R, Botella P, Viaño J: Familial spinal neurofibromatosis. Neuropediatrics; 2007 Apr;38(2):105-8
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  • The daughter also had benign tumors that involved the left optic nerve and chiasm and the left cerebellar hemisphere.
  • [MeSH-major] Neurofibromatosis 1 / genetics. Peripheral Nervous System Neoplasms / genetics. Spinal Nerves

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  • (PMID = 17712740.001).
  • [ISSN] 0174-304X
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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79. Crabtree KL, Arnold PM: Spinal seeding of a pilocytic astrocytoma in an adult, initially diagnosed 18 years previously. Pediatr Neurosurg; 2010;46(1):66-70
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

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  • Pilocytic astrocytoma (PA) is a slow-growing, well-circumscribed grade I glioma generally considered benign, with a low recurrence rate and an excellent prognosis following complete surgical resection.
  • We report a 26-year-old male with an intradural extramedullary PA at the thoracolumbar junction following subtotal cerebellar PA resection 18 years previously.
  • To our knowledge, this is the longest time reported from initial tumor resection of leptomeningeal dissemination to the distal spinal cord.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / pathology. Meningeal Neoplasms / secondary. Neoplasm Seeding. Spinal Cord Neoplasms / secondary

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20516744.001).
  • [ISSN] 1423-0305
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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80. Kansal R, Sharma A, Gaikwad N, Mahore A, Goel A: Cemento-ossifying fibroma presenting as a posterior fossa mass lesion. Turk Neurosurg; 2010 Apr;20(2):265-8
MedlinePlus Health Information. consumer health - Cerebellar Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cemento-ossifying fibromas are benign lesions of the jaw, which arise from the periodontal membrane.
  • We present a case of cementoossifying fibroma involving the petromastoid bone, with the large intracranial component causing compression on the cerebellum.
  • [MeSH-major] Bone Neoplasms / pathology. Cerebellar Diseases / pathology. Dental Cementum / pathology. Fibroma, Ossifying / pathology. Infratentorial Neoplasms / pathology. Mastoid / pathology
  • [MeSH-minor] Adult. Cerebellum / pathology. Cerebellum / radiography. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 20401857.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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81. Gonzalvez Gasch AM, Mirete Ferrer C, Laveda Cano R, Satorres Rosas J: A case of a solid renal mass together with a cystic pancreatic lesion in a 50-year-old patient. JOP; 2005 Mar;6(2):172-7
MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.

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  • Microcystic adenomas are particularly rare among pancreatic cyst neoplasms.
  • They are benign lesions and can present as solitary pancreatic tumors or as a radiological manifestation combined with other cystic and tumoral lesions affecting different organs.
  • [MeSH-major] Adenoma / diagnosis. Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Pancreatic Neoplasms / diagnosis. von Hippel-Lindau Disease / diagnosis
  • [MeSH-minor] Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / pathology. Diagnosis, Differential. Hemangioblastoma / complications. Hemangioblastoma / diagnosis. Hemangioblastoma / pathology. Hematuria / diagnosis. Hematuria / etiology. Hematuria / pathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / pathology. Tomography, X-Ray Computed

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  • (PMID = 15767734.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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82. Ligon AH, Moore SD, Parisi MA, Mealiffe ME, Harris DJ, Ferguson HL, Quade BJ, Morton CC: Constitutional rearrangement of the architectural factor HMGA2: a novel human phenotype including overgrowth and lipomas. Am J Hum Genet; 2005 Feb;76(2):340-8
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  • Here we describe an 8-year-old boy who has a de novo pericentric inversion of chromosome 12, with breakpoints at p11.22 and q14.3, and a phenotype including extreme somatic overgrowth, advanced endochondral bone and dental ages, a cerebellar tumor, and multiple lipomas.
  • His chromosomal inversion was found to truncate HMGA2, a gene that encodes an architectural factor involved in the etiology of many benign mesenchymal tumors and that maps to the 12q14.3 breakpoint.

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  • (PMID = 15593017.001).
  • [ISSN] 0002-9297
  • [Journal-full-title] American journal of human genetics
  • [ISO-abbreviation] Am. J. Hum. Genet.
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / P01 GM061354; United States / NIGMS NIH HHS / GM / GM61354
  • [Publication-type] Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HMGA2 Protein
  • [Other-IDs] NLM/ PMC1196379
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83. Gläsker S, Vortmeyer AO, Lonser RR, Lubensky IA, Okamoto H, Xia JB, Li J, Milne E, Kowalak JA, Oldfield EH, Zhuang Z: Proteomic analysis of hemangioblastoma cyst fluid. Cancer Biol Ther; 2006 May;5(5):549-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Hemangioblastomas are benign CNS tumors that occur sporadically or in patients with von Hippel-Lindau (VHL) disease.
  • The proteomic pattern of intratumoral cyst fluid was furthermore compared to the proteomic pattern of serum, hemangioblastoma tumor tissue, and hemangioblastoma peritumoral cyst fluid.
  • RESULTS: We show that proteomic patterns of intra- and peritumoral cyst fluid are identical Both are highly similar to serum and not to tumor.
  • [MeSH-major] Cerebellar Neoplasms / metabolism. Cyst Fluid / metabolism. Hemangioblastoma / metabolism. Proteome / analysis
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Chromatography, Liquid. Electrophoresis, Gel, Two-Dimensional. Humans. Mass Spectrometry

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  • (PMID = 16627978.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proteome
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84. Franco-Vidal V, Négrevergne M, Darrouzet V: [Vertigo and pathology of the cerebello-pontine angle]. Rev Laryngol Otol Rhinol (Bord); 2005;126(4):223-6
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  • Usually they are due to benign or malignant tumors.
  • Finally very big tumors can be compressive on the cerebellum or on the brainstem inducing also dizziness.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Vertigo / etiology

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  • (PMID = 16496548.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 16
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85. Summers LE, Florez L, Berberian ZJ, Bhattacharjee M, Walsh JW: Postoperative cranial fasciitis. Report of two cases and review of the literature. J Neurosurg; 2007 Jun;106(6):1080-5
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  • The second case is that of a 61-year-old man who underwent suboccipital craniectomy for hypertensive hemorrhage and 2 years later was found to have an enlarging mass at the incision site, causing compression of the cerebellum.
  • Cranial fasciitis is a rare, benign lesion of the cranial region.
  • [MeSH-minor] Adolescent. Brain Hemorrhage, Traumatic / surgery. Cerebellar Neoplasms / surgery. Fatal Outcome. Female. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / surgery. Middle Aged. Neurosurgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 17564183.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Chung KH, Charlton A, Arbuckle S, Chaseling R, Owler BK: Metachronous multifocal desmoid-type fibromatoses along the neuraxis with adenomatous polyposis syndrome. J Neurosurg Pediatr; 2010 Oct;6(4):372-6
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  • Desmoid-type fibromatosis, aggressive fibromatosis, or desmoid tumor is an uncommon benign but locally aggressive fibroblastic lesion.
  • [MeSH-major] Adenomatous Polyposis Coli / pathology. Cerebral Ventricle Neoplasms / pathology. Fibromatosis, Aggressive / pathology. Genes, APC. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adolescent. Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / pathology. Family Health. Humans. Magnetic Resonance Imaging. Male. Medulloblastoma / genetics. Medulloblastoma / pathology. Pedigree

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  • (PMID = 20887112.001).
  • [ISSN] 1933-0715
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Ramachandran R, Lee HS, Matthews B, Shatzel A, Tihan T: Intradural extramedullary leptomeningeal hemangioblastomatosis and paraneoplastic limbic encephalitis diagnosed at autopsy: an unlikely pair. Arch Pathol Lab Med; 2008 Jan;132(1):104-8
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  • Typical cerebellar or spinal cord hemangioblastoma is often solitary and has a benign clinical course, whereas disseminated hemangioblastomatosis is extremely rare.
  • The patient presented with gait problems and cognitive deficits, and was diagnosed with a cervical spinal tumor.
  • [MeSH-major] Dura Mater / pathology. Hemangioblastoma / pathology. Limbic Encephalitis / pathology. Meningeal Neoplasms / pathology
  • [MeSH-minor] Aged. Dementia / complications. Dementia / pathology. Diagnosis, Differential. Fatal Outcome. Humans. Male. Spinal Neoplasms / diagnosis

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  • (PMID = 18181660.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Gläsker S, Lonser RR, Okamoto H, Li J, Jaffee H, Oldfield EH, Zhuang Z, Vortmeyer AO: Proteomic profiling: a novel method for differential diagnosis? Cancer Biol Ther; 2007 Mar;6(3):343-5
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  • The differentiation between hemangioblastoma, a benign vascular brain tumor, and renal cell carcinoma (RCC), a malignant tumor that can metastasize to the brain, is a well-known pathological quandary.
  • She presented with a cystic cerebellar tumor that had typical MRI appearance of a hemangioblastoma.
  • The discrepancy between the benign clinical course and the histologic phenotype could not be clearly resolved using conventional clinical techniques.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Protein Array Analysis / methods. Proteomics. von Hippel-Lindau Disease / diagnosis
  • [MeSH-minor] Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / secondary. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 17471020.001).
  • [ISSN] 1538-4047
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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89. Carlson ML, Beatty CW, Link MJ: High-grade undifferentiated sarcoma of the cerebellopontine angle masquerading as a benign vestibular schwannoma. Otol Neurotol; 2010 Oct;31(8):1350-1
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  • [Title] High-grade undifferentiated sarcoma of the cerebellopontine angle masquerading as a benign vestibular schwannoma.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Neuroma, Acoustic / pathology. Sarcoma / pathology

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  • (PMID = 20010448.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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