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1. Kim EY, Choe YH, Sung K, Park SW, Kim JH, Ko YH: Multidetector CT and MR imaging of cardiac tumors. Korean J Radiol; 2009 Mar-Apr;10(2):164-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multidetector CT and MR imaging of cardiac tumors.
  • The purpose of this article is to provide a current review of the spectrum of multidetector CT (MDCT) and MRI findings for a variety of cardiac neoplasms.
  • In the diagnosis of cardiac tumors, the use of MDCT and MRI can help differentiate benign from malignant masses.
  • Especially, the use of MDCT is advantageous in providing anatomical information and MRI is useful for tissue characterization of cardiac masses.
  • Knowledge of the characteristic MRI findings of benign cardiac tumors or thrombi can be helpful to avoid unnecessary surgical procedures.
  • Presurgical assessment of malignant cardiac tumors with the use of MDCT and MRI may allow determination of the resectability of tumors and planning for the reconstruction of cardiac chambers.
  • [MeSH-major] Heart Neoplasms / pathology. Magnetic Resonance Imaging. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Contrast Media / administration & dosage. Electrocardiography. Hemangioma / pathology. Humans. Lymphoma / pathology. Neoplasms, Connective and Soft Tissue / pathology. Papilloma / pathology

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  • (PMID = 19270863.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 26
  • [Other-IDs] NLM/ PMC2651440
  • [Keywords] NOTNLM ; Cardiac tumor / Magnetic resonance (MR) / Multidetector CT
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2. Padalino MA, Basso C, Milanesi O, Vida VL, Moreolo GS, Thiene G, Stellin G: Surgically treated primary cardiac tumors in early infancy and childhood. J Thorac Cardiovasc Surg; 2005 Jun;129(6):1358-63

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgically treated primary cardiac tumors in early infancy and childhood.
  • OBJECTIVE: Primary heart tumors in childhood are rare and mostly benign.
  • MATERIALS AND METHODS: Between 1986 and 2003, 8 children (3 males and 5 females, age ranging 5 days to 6.7 years, median 78 days) with a clinical diagnosis of cardiac mass were treated with surgery.
  • Diagnosis was made by prenatal echocardiography in 3 patients and by 2-dimensional Doppler echocardiography in 5 patients.
  • RESULTS: Complete surgical excision of the cardiac mass was feasible in all but 1 patient who underwent orthotopic heart transplantation.
  • One patient died of cerebral malignancy 38 months after cardiac transplantation.
  • At a mean follow-up of 69.2 months (range 3-190 months), all the remaining patients are asymptomatic, with good ventricular function on 2-dimensional echocardiography and no signs of residual or recurrent tumor.
  • CONCLUSION: Surgical excision of obstructive cardiac tumors in childhood is safely feasible.
  • Heart transplantation may represent the only therapeutic option when the tumor extensively invades the ventricular walls.
  • Although 2-dimensional echocardiography remains a reliable diagnostic tool, a definite diagnosis of tumor histotype requires a thorough histopathologic characterization.
  • [MeSH-major] Heart Neoplasms / surgery

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  • (PMID = 15942578.001).
  • [ISSN] 0022-5223
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Saxena P, Shehatha J, Naran A, Rajaratnam S, Newman MA, Konstantinov IE: Papillary fibroelastoma of the interventricular septum: mimicking a cardiac myxoma. Tex Heart Inst J; 2010;37(1):119-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary fibroelastoma of the interventricular septum: mimicking a cardiac myxoma.
  • Papillary fibroelastomas are benign cardiac tumors that involve cardiac valves.
  • These tumors are usually asymptomatic and are found incidentally during cardiac surgery or during echocardiographic evaluation in a patient who exhibits cardiac symptoms.
  • However, these tumors may cause major thromboembolic complications.

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  • (PMID = 20200644.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2829813
  • [Keywords] NOTNLM ; Fibroelastoma/diagnosis/pathology/surgery / heart neoplasms/pathology/surgery / treatment outcome
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4. Elbardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ, Schaff HV: Survival after resection of primary cardiac tumors: a 48-year experience. Circulation; 2008 Sep 30;118(14 Suppl):S7-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Survival after resection of primary cardiac tumors: a 48-year experience.
  • BACKGROUND: Primary cardiac tumors are rare but have the potential to cause significant morbidity if not treated in an appropriate and timely manner.
  • METHODS AND RESULTS: From 1957 to 2006, 323 consecutive patients underwent surgical resection of primary cardiac tumors; 163 (50%) with myxomas, 83 (26%) with papillary fibroelastomas, 18 (6%) with fibromas, 12 (4%) with lipomas, 28 (9%) with other benign primary cardiac tumors, and 19 (6%) with primary malignant tumors.
  • Univariate analysis indicated that patients who underwent resection of fibromas and myxomas had superior survival characteristics in comparison to the remainder of tumor variants; these results were consistent after adjusting for age at surgery, year of surgery, and cardiovascular risk factors.
  • Based on actuarial characteristics of the 2002 U.S. population, patients who underwent myxoma resection had survival characteristics that were not significantly different from that of an age and gender matched population (SMR 1.11, P=0.57) whereas those who underwent resection of fibromas (SMR 11.17, P=0.002), papillary fibroelastomas (SMR 3.17, P=0.0003), lipomas (SMR 5.0, P=0.0003), other benign tumors (SMR 4.63, P=0.003), and malignant tumors (SMR 101, P<0.0001) had significantly poorer survival characteristics.
  • Furthermore, malignant tumors in younger patients were highly fatal (HR 0.899, P<0.0001).
  • Although the most significant predictor of mortality was tumor histology, survival was also influenced the by the duration of CPB and NYHA III/IV; the impact of these risk factors varied with time.
  • CONCLUSIONS: Surgical resection of primary cardiac tumors is associated with excellent long-term survival; patients with cardiac myxomas have survival characteristics that are not significantly different from that of a general population.
  • Predictors of mortality are primarily related to tumor histology but also include clinical characteristics such as symptomatology and duration of CPB.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / mortality. Heart Neoplasms / surgery
  • [MeSH-minor] Adult. Age Distribution. Aged. Cardiopulmonary Bypass. Female. Fibroma / mortality. Fibroma / surgery. Humans. Incidence. Kaplan-Meier Estimate. Lipoma / mortality. Lipoma / surgery. Male. Middle Aged. Multivariate Analysis. Myxoma / mortality. Myxoma / surgery. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / etiology. Proportional Hazards Models. Risk Assessment. Risk Factors. Severity of Illness Index. Sex Distribution. Time Factors

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  • (PMID = 18824772.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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5. Karpuz V, Ikitimur B, Karpuz H: [A survey of heart tumors: clinical and echocardiographic approach]. Anadolu Kardiyol Derg; 2007 Dec;7(4):427-35

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A survey of heart tumors: clinical and echocardiographic approach].
  • Heart tumors can be primary in origin, can develop from direct extension of a neighboring tumor or they can be the manifestation of metastasis of a distant tumor.
  • Myxomas are the most frequently encountered primary benign cardiac tumors.
  • Primary malignant tumors of the heart are rare, and they are mostly sarcomatous in structure.
  • Secondary heart tumors constitute a wide spectrum, nevertheless they most frequently originate from lung cancer, breast cancer and hematological malignancies.
  • Heart tumors may involve myocardium, endocardium, epicardium, pericardium, or any combination of the aforementioned layers.
  • On the other hand, the usual site for metastasis to the heart is the pericardium.
  • These tumors do not have a well- established classification.
  • Clinical findings are usually non-specific and transient in nature and frequently present late in the disease process.
  • Surgery is the principal therapeutic option in benign tumors and when recurrences are not taken into account, they have favorable prognoses.
  • Since surgical resection is usually incomplete in malignant tumors, therapy must be individualized for each patient; even with adjuvant chemotherapy, postoperative survival is usually short.
  • Metastases to the heart are usually approached symptomatically except for exceptional cases.
  • [MeSH-major] Heart Neoplasms / diagnosis
  • [MeSH-minor] Echocardiography, Transesophageal. Fibroma / diagnosis. Fibroma / pathology. Fibroma / radiography. Fibroma / ultrasonography. Hemangioma / diagnosis. Hemangioma / pathology. Hemangioma / radiography. Hemangioma / ultrasonography. Humans. Magnetic Resonance Imaging. Myoma / diagnosis. Myoma / pathology. Myoma / radiography. Myoma / ultrasonography. Myxoma / diagnosis. Myxoma / pathology. Myxoma / radiography. Myxoma / ultrasonography. Tomography, X-Ray Computed

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  • (PMID = 18065342.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 49
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6. Jain D, Maleszewski JJ, Halushka MK: Benign cardiac tumors and tumorlike conditions. Ann Diagn Pathol; 2010 Jun;14(3):215-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cardiac tumors and tumorlike conditions.
  • Benign primary cardiac tumors and tumorlike conditions are rare, yet important surgical and autopsy pathology specimens.
  • Some cardiac tumors arise in the setting of genetic disorders.
  • Providing the correct diagnosis for a cardiac mass lesion will aid in patient care and genetic counseling.
  • Therefore, a familiarity of these tumors is essential for both surgical and forensic pathologists.
  • It also provides differential diagnoses and key facts to differentiate between similar appearing tumors.
  • [MeSH-major] Fibroma / pathology. Heart Neoplasms / pathology. Myxoma / pathology. Rhabdomyoma / pathology
  • [MeSH-minor] Female. Heart Diseases / pathology. Humans. Male

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  • (PMID = 20471569.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 158
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7. Restrepo CS, Largoza A, Lemos DF, Diethelm L, Koshy P, Castillo P, Gomez R, Moncada R, Pandit M: CT and MR imaging findings of benign cardiac tumors. Curr Probl Diagn Radiol; 2005 Jan-Feb;34(1):12-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CT and MR imaging findings of benign cardiac tumors.
  • This imaging review describes the appearance of benign cardiac tumors on CT and MRI.
  • Although rare, benign tumors outnumber their primary malignant counterparts three to one.
  • Since mortality varies directly with invasion, identifying the neoplasm at an early stage helps focus treatment, especially in benign cases, which generally respond well to surgical resection.
  • In adults and children, myxomas and rhabdomyomas, respectively, represent the most common benign tumors, which can be grouped into tissue-specific subtypes, such as rhabdomyomas, fibromas, lipomas, teratomas, etc.
  • Besides their variable prevalence in particular age groups, these tumors also differ with regard to their gender predilection, location, and number.
  • As with all cardiac tumors, echocardiographic findings usually suggest the initial diagnosis but cross-sectional imaging with CT and MRI can help resolve diagnostically challenging cases.
  • Through dynamic techniques, MRI, in addition to morphologic characterization, can depict the pathophysiological effects of these tumors, for instance, with regard to myocardial contraction, valvular function, or blood flow.
  • [MeSH-major] Heart Neoplasms / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 15644859.001).
  • [ISSN] 0363-0188
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 49
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8. Caballero PE: Left atrial sarcoma presenting as cerebral infarction. Neurologist; 2008 Mar;14(2):131-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Primary heart tumors are rare and most of them are benign.
  • The majority of benign cardiac tumors are myxomas, although almost all malignant cardiac tumors are sarcomas.
  • Malignant cardiac tumors usually appear in children.
  • METHODS: There have been cases described of stroke secondary to embolism caused by cardiac sarcomas, but it is rarely the first manifestation of the tumor.
  • RESULTS: We describe a 48-year-old man who suffered a cardioembolic stroke secondary to cardiac sarcoma.
  • CONCLUSION: Malignant cardiac tumors typically appear through 1 of 4 mechanisms: obstruction to blood flow and interference with valve function; local invasion causing arrhythmias or pericardial effusion; embolic phenomena or systemic symptoms.
  • We analyze the characteristics of cardiac sarcoma and the pathophysiology of embolism.
  • [MeSH-major] Cerebral Infarction / etiology. Heart Neoplasms / complications. Intracranial Embolism / etiology. Sarcoma / complications
  • [MeSH-minor] Heart Atria. Humans. Male. Middle Aged

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  • (PMID = 18332844.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Mariscalco G, Bruno VD, Borsani P, Dominici C, Sala A: Papillary fibroelastoma: insight to a primary cardiac valve tumor. J Card Surg; 2010 Mar;25(2):198-205

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary fibroelastoma: insight to a primary cardiac valve tumor.
  • Papillary fibroelastomas are rare benign cardiac tumors.
  • The pathophysiology and management of these tumors is the subject of this review.
  • [MeSH-major] Fibroma / etiology. Fibroma / surgery. Heart Neoplasms / etiology. Heart Neoplasms / surgery
  • [MeSH-minor] Cardiac Surgical Procedures. Diagnosis, Differential. Echocardiography. Heart Valves. Humans

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  • (PMID = 20149002.001).
  • [ISSN] 1540-8191
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 80
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10. Kajihara N, Tanoue Y, Eto M, Tomita Y, Masuda M, Morita S: Surgical experience of cardiac tumors: early and late results. Surg Today; 2006;36(7):602-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical experience of cardiac tumors: early and late results.
  • PURPOSE: Cardiac tumors include benign and malignant neoplasms that arise within the cardiac chambers or myocardium.
  • This study summarizes our surgical experiences with cardiac tumors.
  • METHODS: Between 1975 and 2003, 51 patients with cardiac tumors were surgically treated.
  • Forty-seven cardiac myxomas were excised in 46 patients with an average age of 51.7 +/- 18 years.
  • The preoperative symptoms included congestive heart failure (37%) and embolism (30%).
  • Benign nonmyxomatous tumors.
  • Three patients with a mean age of 26.3 +/- 19.0 years showed benign nonmyxomatous tumors.
  • Malignant tumors.
  • Two patients were diagnosed to have malignant tumors and although there was no perioperative death, both died postoperatively within 6 months.
  • CONCLUSIONS: Cardiac myxomas and nonmyxomatous benign cardiac tumors show excellent results after a surgical excision, with a low morbidity and mortality.
  • A surgical resection should thus be considered as a treatment option for patients with malignant tumors.
  • [MeSH-major] Heart Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Cardiac Surgical Procedures / methods. Child, Preschool. Embolism / etiology. Female. Heart Failure / etiology. Humans. Male. Middle Aged. Myxoma / mortality. Myxoma / surgery

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  • (PMID = 16794794.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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11. Blackmon SH, Kassis ES, Ge Y, Goldfarb R, Reardon M: Left atrial myxoma embolus to the renal artery: should a nephrectomy be advised? Ann Thorac Surg; 2010 Jul;90(1):289-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac myxoma represents the most common primary cardiac tumor, which accounts for 75% of all benign cardiac tumors.
  • Resection is generally recommended for cardiac myxomata; once identified but less understood is what to do with systemic emboli.
  • Excision of the tumor required cardiac autotransplantation and mitral valve replacement.
  • [MeSH-major] Heart Neoplasms / surgery. Myxoma / surgery. Neoplastic Cells, Circulating / pathology. Nephrectomy. Renal Artery Obstruction / surgery. Vascular Neoplasms / surgery
  • [MeSH-minor] Cardiac Surgical Procedures. Humans. Male. Renal Artery / pathology. Renal Artery / surgery. Replantation. Young Adult

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20609801.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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12. Hu SS, Wang XQ, Xu JP, Sun LZ, Liu YL: [Experiences in surgical treatment of cardiac tumors]. Zhonghua Yi Xue Za Zhi; 2006 Mar 21;86(11):766-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Experiences in surgical treatment of cardiac tumors].
  • OBJECTIVE: To summarize the experiences in surgical treatment of cardiac tumors.
  • METHODS: The results of surgical treatment of 494 patients with cardiac tumors hospitalized from 1975 to 2004, aged 43 +/- 16 (4 months to 78 years), 432 with myxoma, 27 with benign nonmyxoma, and 35 with malignant tumors, were analyzed.
  • RESULTS: Complete resection of malignant tumor was achieved in 10 cases (28.6%), and subtotal resection was achieved in 15 cases (42.9%).
  • Only biopsy was performed in 10 patients (28.6%) because of extensive metastasis of tumor.
  • Hospital death occurred in 11 myxoma patients (2.5%), and 3 malignant tumor patients (8.6%), and none of the benign non-myxoma tumor patients.
  • Follow-up for malignant tumors showed 18 (51.4%) late deaths because of recurrence or metastasis, occurring 2 months to 2 years after operation.
  • CONCLUSION: Excellent immediate and long-term operative results can be obtained for benign cardiac tumors.
  • However, for the patients with malignant tumors the survival chances are dismal.
  • [MeSH-major] Heart Neoplasms / surgery. Myxoma / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Cardiac Surgical Procedures. Child. Child, Preschool. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 16681953.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Reardon MJ, Walkes JC, Benjamin R: Therapy insight: malignant primary cardiac tumors. Nat Clin Pract Cardiovasc Med; 2006 Oct;3(10):548-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Therapy insight: malignant primary cardiac tumors.
  • Benign cardiac tumors are resected with a high degree of success with modern cardiac surgical techniques.
  • Malignant cardiac tumors, however, continue to pose a therapeutic challenge to cardiac surgeons and oncologists because of the technical difficulty involved in extensive cardiac resections and the aggressive biological nature of the tumors.
  • The majority of malignant cardiac tumors are sarcomas and can be categorized as right heart sarcoma, left heart sarcoma or pulmonary artery sarcoma.
  • Right heart sarcomas are generally angiosarcomas, which infiltrate widely and metastasize early.
  • Left heart sarcomas, although large, are often less infiltrative and metastasize later than right heart sarcomas, but a similar approach to treatment is usually employed.
  • Surgical resection is more-frequently necessary for left heart sarcomas because of intracardiac blood flow obstruction and congestive heart failure, although the anatomic position and relation of these tumors to cardiac structures can complicate surgery.
  • We have developed and employed the technique of cardiac autotransplantation, which involves cardiac excision, ex vivo tumor resection with cardiac reconstruction, and cardiac reimplantation, to lessen these technical difficulties.
  • [MeSH-major] Heart Neoplasms / surgery. Hemangiosarcoma / surgery. Histiocytoma, Malignant Fibrous / surgery. Pulmonary Artery / surgery. Vascular Neoplasms / surgery
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Cardiac Surgical Procedures. Chemotherapy, Adjuvant. Humans. Neoplasm Invasiveness. Neoplasm Metastasis. Prognosis

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  • (PMID = 16990840.001).
  • [ISSN] 1743-4297
  • [Journal-full-title] Nature clinical practice. Cardiovascular medicine
  • [ISO-abbreviation] Nat Clin Pract Cardiovasc Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 23
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14. Riberi A, Gariboldi V, Grisoli D, Collart F: [Cardiac tumors]. Rev Pneumol Clin; 2010 Feb;66(1):95-103

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac tumors].
  • [Transliterated title] Les tumeurs cardiaques.
  • Primary cardiac tumor is a rare disease, with an incidence ranging from 0.001 to 0.03%.
  • Eighty percent of them are benign tumors, and among them 70% are myxomas, the others are: fibroelastoma, rhabdomyoma, fibroma, angioma and lipoma.
  • Primary malignant tumors of heart are in 95% of cases sarcomas, the remaining 5% are lymphomas.
  • Cardiac's metastases are more frequent than primary tumors.
  • Diagnosis is made by echocardiography TAC and MRI.
  • Whereas surgery is indicated in patients with benign tumors, or localised sarcomas, chemotherapy in those with widespread disease and radiotherapy and chemotherapy in lymphoma.
  • Prognosis is excellent in benign cardiac tumor.
  • [MeSH-major] Heart Neoplasms / secondary. Heart Neoplasms / surgery
  • [MeSH-minor] Angiography. Chemotherapy, Adjuvant. Combined Modality Therapy. Diagnosis, Differential. Echocardiography. Humans. Magnetic Resonance Imaging. Myocardium / pathology. Myxoma / diagnosis. Myxoma / pathology. Myxoma / surgery. Prognosis. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

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  • [Copyright] Copyright (c) 2010. Published by Elsevier Masson SAS.
  • (PMID = 20207301.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 28
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15. Vaideeswar P, Butany JW: Benign cardiac tumors of the pluripotent mesenchyme. Semin Diagn Pathol; 2008 Feb;25(1):20-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cardiac tumors of the pluripotent mesenchyme.
  • Among benign primary cardiac tumors, myxomas and papillary fibroelastomas are the most common.
  • Cardiac myxomas arise from pluripotent mesenchymal cells and are seen as intracardiac, glistening polypoid masses arising most frequently from the interatrial septum in the left atrium.
  • These tumors can be sporadic or familial.
  • Embolism is often the mode of presentation for both of the tumors; myxomas are also associated with obstructive and constitutional symptoms.
  • In contrast, neurogenic tumors (paraganglia or nerve sheath tumors) are exceedingly rare and occur as epicardial and infrequently as intracatdiac masses.
  • The tumors are often incidentally diagnosed by the usual echocardiography, but magnetic resonance imaging is useful for further characterization of the tumors.
  • The tumors are, in general, treated by surgical resection, but may require a little or at times more significant reconstruction.
  • Among these tumors, the myxomas are associated with a higher rate of recurrences.
  • [MeSH-major] Heart Neoplasms. Mesoderm / pathology. Myxoma. Neoplasms, Fibroepithelial. Pluripotent Stem Cells / pathology

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  • (PMID = 18350919.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 46
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16. Bruckner BA, Reardon MJ: Benign cardiac tumors: a review. Methodist Debakey Cardiovasc J; 2010 Jul-Sep;6(3):20-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cardiac tumors: a review.
  • Tumors of the heart are very uncommon and can occur as primary or secondary metastatic tumors.
  • Metastatic tumors are over 40 times more common than primary cardiac tumors.
  • Primary tumors of the heart are benign in 75% of cases and malignant in 25%.
  • We first reported our institutional experience with all primary cardiac tumors in 2003.
  • Of the 85 patients seen, 17 had malignant tumors (20%) and 68 had benign tumors (80%).
  • These benign tumors and our subsequent experience form the basis of this report.
  • [MeSH-major] Heart Neoplasms
  • [MeSH-minor] Adult. Cardiac Surgical Procedures. Diagnostic Imaging. Female. History, 16th Century. History, 20th Century. Humans. Predictive Value of Tests. Treatment Outcome

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  • (PMID = 20834207.001).
  • [ISSN] 1947-6094
  • [Journal-full-title] Methodist DeBakey cardiovascular journal
  • [ISO-abbreviation] Methodist Debakey Cardiovasc J
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Portraits
  • [Publication-country] United States
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17. Orlandi A, Ferlosio A, Angeloni C, Ciucci A, Giusto Spagnoli L: [Cardiac tumors]. Pathologica; 2005 Jun;97(3):115-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac tumors].
  • [Transliterated title] I tumori cardiaci.
  • Primary cardiac tumors are rare and their subdivision often difficult because of their unknown origin.
  • In the most recent classification, cardiac tumors are divided into benign (about 75% and malignant neoplasms in relationship to their tissue differentiation (rhabdomyoma, haemangioma, etc.) or uncertain aetiology (myxoma, papillary fibroelastoma).
  • Primary malignant tumors are maimly represented by sarcomas.
  • The most frequent tumor is cardiac myxoma, which by itself represents about 50% of all primary cardiac neoplasms.
  • Although non-invasive technologies as trans-esophageal ecocardiography allow the detection and exact localization of cardiac mass, clinical diagnosis is often tardive.
  • This is due, besides the intrinsic rarity, to two main factors: first, the tumor is often asymptomatic (incidental autopic finding) or; alternatively, it may show aspecif symptoms mimicking heart failure or other pathologies.
  • In this article, clinicopathological features of main primary cardiac tumors are presented.
  • Investigation of the histogenesis of some of these neoplasms is still a primary field of research.
  • [MeSH-major] Heart Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Glomus Tumor / pathology. Hemangioma / pathology. Humans. Male. Middle Aged. Myxoma / genetics. Myxoma / pathology. Neoplasm Proteins / analysis. Papilloma / pathology. Pericytes / pathology. Rhabdomyoma / pathology. Sarcoma / chemistry. Sarcoma / pathology

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  • (PMID = 16259277.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  • [Number-of-references] 29
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18. Figueroa-Torres Y, Martínez-Ojeda JA, Franqui-Rivera H, Martínez-Toro J: Benign cardiac neoplasms: the experience at the Cardiovascular Center of Puerto Rico and the Caribbean. P R Health Sci J; 2008 Dec;27(4):373-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cardiac neoplasms: the experience at the Cardiovascular Center of Puerto Rico and the Caribbean.
  • INTRODUCTION: Neoplasms of the heart are extremely rare and difficult to diagnose.
  • In this study, we intend to describe the experience at the Cardiovascular Center of Puerto Rico and the Caribbean (CCPRC) dealing with benign cardiac neoplasms.
  • A total of 77 cases with a diagnosis of Benign Heart Neoplasm were found from 1992 to 2008 but only those with an official pathologic report (n = 43) were considered.
  • For interpretation of results, a p-value < 0.05 was considered significant.
  • RESULTS: The mean age for diagnosis was 51.49 years.
  • The most common presenting symptom by which these patients sought medical attention was congestive heart failure (35%), followed by chest pain (18%) and neurologic symptoms (14%).
  • The most common location of the mass was the left atrium (81%) and overall, the most common heart neoplasm in this study was myxoma (83.7%).
  • CONCLUSIONS: This study of a total of 43 pathologically confirmed benign cardiac neoplasms admitted to the Cardiovascular Center of Puerto Rico and the Caribbean from 1992 to 2008 validates the fact that heart neoplasms represent a fairly rare diagnosis.
  • It is also consistent with previously published series that establish myxoma as the most common of these benign neoplasms.
  • [MeSH-major] Heart Neoplasms / diagnosis

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  • (PMID = 19069370.001).
  • [ISSN] 0738-0658
  • [Journal-full-title] Puerto Rico health sciences journal
  • [ISO-abbreviation] P R Health Sci J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Puerto Rico
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19. Bossert T, Gummert JF, Battellini R, Richter M, Barten M, Walther T, Falk V, Mohr FW: Surgical experience with 77 primary cardiac tumors. Interact Cardiovasc Thorac Surg; 2005 Aug;4(4):311-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical experience with 77 primary cardiac tumors.
  • BACKGROUND: To assess the prognosis and to develop management strategies for primary cardiac tumors all patients were included in an ongoing study.
  • 1994 until December 2003 we prospectively evaluated all patients with cardiac tumors.
  • RESULTS: There were a total of 77 primary cardiac tumors.
  • Seventy-three were benign: myxoma (n=59), papillary fibroelastoma (n=11), lipoma (n=2), fibroma (n=1) and four malignant sarcoma (n=4).
  • There were 4 primary cardiac sarcomas, located in the right ventricle (n=2), the pulmonary valve (n=1) and left atrium (n=1).
  • Minimal invasive right thoracotomy was utilized in 19 of 73 patients all with benign tumor.
  • There were two early deaths (3%): a myxoma patient with triple vessel disease and a LVEF less than 30% and one sarcoma patient.
  • No recurrence or late death was observed in the group of benign tumors.
  • However, two remaining patients with sarcoma had recurrent disease 10 and 15 month later, respectively.
  • CONCLUSION: Surgical excision of benign cardiac tumors is a safe and curative treatment, which is feasible using minimally invasive right thoracotomy approach and provides excellent results.
  • However, therapy of malignant cardiac tumors continues to have a poor prognosis despite individualization of approach.

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  • (PMID = 17670419.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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20. Kim RW, Jeffery ME, Smith MJ, Wilensky RL, Woo EY, Woo YJ: Minimally invasive resection of papillary fibroelastoma in a high-risk patient. J Cardiovasc Med (Hagerstown); 2007 Aug;8(8):639-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Papillary fibroelastomas are rare, benign cardiac tumors that typically mandate surgical resection.
  • We describe the minimally invasive resection of a right atrial fibroelastoma performed on a beating heart via right mini-thoracotomy in a patient complicated by a previous laryngectomy, radiation therapy, and a left-sided pulmonary malignancy.
  • [MeSH-major] Cardiac Surgical Procedures. Fibroma / surgery. Heart Neoplasms / surgery. Papillary Muscles / surgery
  • [MeSH-minor] Carotid Stenosis / complications. Heart Atria / surgery. Humans. Laryngectomy / adverse effects. Lung Neoplasms / complications. Male. Middle Aged. Minimally Invasive Surgical Procedures. Radiotherapy / adverse effects. Risk Assessment. Thoracotomy. Tomography, X-Ray Computed. Tracheostomy / adverse effects. Treatment Outcome

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  • (PMID = 17667039.001).
  • [ISSN] 1558-2027
  • [Journal-full-title] Journal of cardiovascular medicine (Hagerstown, Md.)
  • [ISO-abbreviation] J Cardiovasc Med (Hagerstown)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Maraj S, Pressman GS, Figueredo VM: Primary cardiac tumors. Int J Cardiol; 2009 Apr 3;133(2):152-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac tumors.
  • Primary cardiac tumors are a rare entity compared to tumors that metastasize to the heart.
  • Patients with such tumors may be asymptomatic.
  • It is important for the clinician to have a high index of suspicion when evaluating a patient presenting with signs and systemic symptoms concerning possible malignancy, plus cardiac specific symptoms or complications.
  • These can include new onset dyspnea, congestive heart failure, arrhythmias or murmurs varying with body positions.
  • Imaging, particularly the use of echocardiography, remains the cornerstone of diagnosis, and may be combined with new imaging modalities of cardiac CT and MRI.
  • The aim of this paper is to describe the epidemiology and pathophysiology of the various benign and malignant primary cardiac tumors.
  • [MeSH-major] Heart Neoplasms / epidemiology. Heart Neoplasms / physiopathology

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  • [CommentIn] Int J Cardiol. 2011 Oct 6;152(1):e4-5 [20934228.001]
  • (PMID = 19128845.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 42
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22. Yu K, Liu Y, Wang H, Hu S, Long C: Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases. Interact Cardiovasc Thorac Surg; 2007 Oct;6(5):636-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases.
  • The purpose of this study was to review the current clinical experience and pathological characteristics of cardiac tumors.
  • We retrospectively reviewed 33,108 consecutive cases of cardiac operations performed at our institution from October 1996 to March 2005.
  • There were 242 cases confirmed histologically as cardiac tumors.
  • Among them, 234 patients were diagnosed with primary heart tumors, revealing a prevalence of 0.71% among the corresponding period cardiac operations.
  • Of primary cardiac tumors, the incidence of benign neoplasm was much higher than malignant masses (90.6% vs. 9.4%, P<0.01).
  • The most common benign cardiac tumor was myxoma (86.8%).
  • Mesenchymoma and angiosarcoma were the most common primary malignant cardiac tumors.
  • The prevalence rates of cardiac tumors were quite different among age groups.
  • Benign non-myxoma tumors are more likely to occur in the ventricular (64.3%).
  • The primary malignant tumors have a tendency to be of multi-center origination (23%).
  • All the secondary cardiac tumors were located in the right side of the heart.
  • This study, using a relatively large sample, reveals the clinical incidences and pathological characteristics of various cardiac tumors in the Chinese population.
  • [MeSH-major] Asian Continental Ancestry Group / statistics & numerical data. Heart Neoplasms. Hemangiosarcoma. Lipoma. Mesenchymoma. Myxoma. Rhabdomyoma
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Child. Child, Preschool. China / epidemiology. Female. Humans. Incidence. Infant. Male. Middle Aged. Neoplasm Metastasis. Prevalence. Retrospective Studies. Sex Distribution

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  • (PMID = 17670730.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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23. Castillo JG, Silvay G: Characterization and management of cardiac tumors. Semin Cardiothorac Vasc Anesth; 2010 Mar;14(1):6-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization and management of cardiac tumors.
  • Cardiac tumors are infrequent clinical entities with an autopsy frequency ranging from 0.001% to 0.030%.
  • The occurrence of metastatic cardiac tumors has been reported a 100-fold more commonly than primary lesions.
  • Three quarters of primary cardiac tumors are benign; approximately half of these are cardiac myxomas, and the rest are lipomas, papillary fibroelastomas, and rhabdomyomas.
  • Among malignant primary cardiac tumors, the most reported are those histopathologically considered as undifferentiated, followed by angiosarcomas and leiomyosarcomas.
  • Traditionally, cardiac tumors have been identified as curious autopsy findings resulting in a literature paucity of large clinical series, therefore, providing knowledge mostly based on case report collection.
  • However, recent technological advances in noninvasive imaging modalities such as echocardiography and cardiac magnetic resonance imaging (MRI) have resulted in a rapid acquisition of real-time heart images with high spatial and temporal resolution and an excellent tissue characterization of the tumor.
  • This consequent earlier, more frequent, and more complete assessment of cardiac tumors before significant symptoms develop has challenged cardiologists, cardiac anesthesiologists, and surgeons to create a tailored referral pattern and approach.
  • [MeSH-major] Heart Neoplasms / therapy. Lipoma / therapy. Myxoma / therapy
  • [MeSH-minor] Adult. Child. Echocardiography / methods. Fibroma / diagnosis. Fibroma / pathology. Fibroma / therapy. Humans. Magnetic Resonance Imaging / methods. Rhabdomyoma / diagnosis. Rhabdomyoma / pathology. Rhabdomyoma / therapy. Time Factors

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  • (PMID = 20472615.001).
  • [ISSN] 1940-5596
  • [Journal-full-title] Seminars in cardiothoracic and vascular anesthesia
  • [ISO-abbreviation] Semin Cardiothorac Vasc Anesth
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 81
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24. Hayashi H, Hidaka F, Kiriyama T, Sato H, Takagi R, Kumita S: A left ventricular lipoma diagnosed on three-dimensional electrocardiogram-gated cardiac computed tomography. Heart Vessels; 2008 Sep;23(5):366-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A left ventricular lipoma diagnosed on three-dimensional electrocardiogram-gated cardiac computed tomography.
  • Cardiac lipomas are extremely rare primary benign cardiac tumors.
  • The cardiac lipoma was qualitatively evaluated and its location was accurately determined noninvasively with the use of three-dimensional images reconstructed from data acquired by electrocardiogram-gated cardiac computed tomography (CT).
  • [MeSH-major] Electrocardiography / methods. Heart Neoplasms / radiography. Imaging, Three-Dimensional. Lipoma / radiography. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Diagnosis, Differential. Heart Ventricles. Humans. Male. Middle Aged

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  • (PMID = 18810588.001).
  • [ISSN] 0910-8327
  • [Journal-full-title] Heart and vessels
  • [ISO-abbreviation] Heart Vessels
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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25. Kosar F, Sincer I, Kuzucu A, Nisanoglu V, Gunen H: A case of a large intrapericardial lipoma occupying pericardial space: an unusual complication of a coronary artery bypass surgery. J Card Surg; 2007 Sep-Oct;22(5):427-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although cardiac lipomas are quite rare, they represent the second most common primary benign cardiac tumors.
  • [MeSH-major] Coronary Artery Bypass. Heart Neoplasms / diagnosis. Lipoma / diagnosis. Pericardium / pathology

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  • (PMID = 17803584.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Ramasubbu K, Wheeler TM, Reardon MJ, Dokainish H: Visceral pericardial hemangioma: unusual location for a rare cardiac tumor. J Am Soc Echocardiogr; 2005 Sep;18(9):981
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Visceral pericardial hemangioma: unusual location for a rare cardiac tumor.
  • Coronary angiography revealed no significant coronary disease, but suggested a mass posterior to the heart.
  • Magnetic resonance imaging confirmed the presence of the tumor, without extension into adjacent cardiac chambers or pericardial effusion.
  • At operation, a 4.6- x 3.0-cm tumor attached to the visceral pericardium was excised.
  • Pathologic section resulted in a diagnosis of hemangioma.
  • Hemangiomas account for 2% to 5% of benign cardiac tumors, arising from the cardiac ventricles, atria, valves, and, rarely, the epicardium/pericardium.
  • This case illustrates a very rare location for an unusual benign cardiac tumor.
  • [MeSH-major] Heart Neoplasms / surgery. Heart Neoplasms / ultrasonography. Hemangioma / surgery. Hemangioma / ultrasonography. Pericardium / surgery. Pericardium / ultrasonography

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  • (PMID = 16153530.001).
  • [ISSN] 1097-6795
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Rivera-Dávila AD, Rodríguez-Ospina L: Primary cardiac and pericardial tumors. Bol Asoc Med P R; 2008 Oct-Dec;100(4):48-54

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac and pericardial tumors.
  • Primary cardiac tumors are rare, with a reported prevalence of 0.001 to 0.03% at autopsy series.
  • Almost 75% of all primary tumors of the heart are benign, with primary malignant tumors accounting for the other 25%.
  • Nearly half of the benign cardiac tumors are myxomas.
  • Other primary tumors include papillary fibroelastoma, rhabdomyoma, fibroma, lipoma and hemangioma.
  • In this review article, the clinical, pathologic and diagnostic feature of primary benign cardiac tumors is presented.
  • In very rare occasions malignant tumors of the heart could be encounter such as primary sarcomas of the heart constituting less than 25% of primary cardiac tumors found in clinical practice.
  • Cardiac sarcomas represent the commonest histology of primary malignant cardiac tumors, with angiosarcomas making up 33% of the cases.
  • [MeSH-major] Heart Neoplasms. Pericardium
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child. Child, Preschool. Diagnosis, Differential. Echocardiography. Electrocardiography. Female. Humans. Infant. Infant, Newborn. Male. Middle Aged. Myocardium / pathology. Sex Factors. Tomography, X-Ray Computed

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  • (PMID = 19400529.001).
  • [ISSN] 0004-4849
  • [Journal-full-title] Boletín de la Asociación Médica de Puerto Rico
  • [ISO-abbreviation] Bol Asoc Med P R
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Puerto Rico
  • [Number-of-references] 46
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28. Grabysa R, Moczulska B, Artemiuk A, Olszewski R, Kubik L: [Thrombus or tumour of the mitral valve--a case of 75-year-old woman with acute coronary syndrome and aortic insufficiency]. Pol Merkur Lekarski; 2009 Nov;27(161):393-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Thrombus or tumour of the mitral valve--a case of 75-year-old woman with acute coronary syndrome and aortic insufficiency].
  • Papillary fibroelastomas are rare, primary, benign cardiac tumors most frequently located in the heart valves.
  • We provide a differential diagnosis and review of the literature concerning the pathologic intracardiac masses affecting cardiac valves.
  • [MeSH-major] Acute Coronary Syndrome / complications. Fibroma / diagnosis. Heart Neoplasms / diagnosis. Heart Valve Diseases / diagnosis. Mitral Valve / ultrasonography
  • [MeSH-minor] Aged. Aortic Valve Insufficiency / complications. Diagnosis, Differential. Echocardiography. Female. Humans. Thrombosis / diagnosis. Thrombosis / etiology

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  • (PMID = 19999803.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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29. Kovacević M, Simić O, Matana A, Lucin K, Stifter S: Pulmonary valve papillary fibroelastoma. A case report. Tumori; 2005 Jul-Aug;91(4):364-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient had no clinical or constitutional symptoms suggesting the presence of an intracardiac tumor.
  • Routine preoperative transthoracic echocardiography revealed a pulmonary valve tumor.
  • Histopathological analysis resulted in a diagnosis of papillary fibroelastoma.
  • Papillary fibroelastomas are rare and benign cardiac tumors.
  • They usually arise from the cardiac valves.
  • [MeSH-major] Fibroma. Heart Neoplasms. Pulmonary Valve
  • [MeSH-minor] Coronary Artery Bypass. Female. Humans. Incidental Findings. Middle Aged. Pulmonary Artery / surgery. Vascular Neoplasms / surgery

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  • (PMID = 16277107.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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30. Chen MS, Sun JP, Asher CR: A right atrial mass and a pseudomass. Echocardiography; 2005 May;22(5):441-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Leading etiologies of right atrial masses are tumor, thrombi, and vegetations.
  • We present two cases of right atrial masses, a cardiac lipoma and an artifact.
  • Clinical and echocardiographic characteristics of benign cardiac tumors are reviewed.
  • We then highlight the importance of considering artifact in the differential diagnosis of atrial masses.
  • Finally, we discuss echocardiographic characteristics of right atrial masses that may provide clues for diagnosis.
  • Right atrial masses, often detected incidentally during imaging studies, are uncommon and can be due to many etiologies including tumors, thrombus, vegetations, normal variants, and artifacts.
  • [MeSH-major] Artifacts. Echocardiography. Heart Neoplasms / diagnosis. Lipoma / diagnosis
  • [MeSH-minor] Aged. Cardiac Surgical Procedures. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 15901299.001).
  • [ISSN] 0742-2822
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Sparrow PJ, Kurian JB, Jones TR, Sivananthan MU: MR imaging of cardiac tumors. Radiographics; 2005 Sep-Oct;25(5):1255-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MR imaging of cardiac tumors.
  • Magnetic resonance (MR) imaging is an important tool in the evaluation of cardiac neoplasms.
  • Recent improvements in pulse sequences for cardiac MR imaging have led to superior image quality, with reduced motion artifact and improved signal-to-noise ratio and tissue contrast.
  • Although there is some overlap in the MR imaging appearances of cardiac tumors, particularly of primary malignancies, differences in characteristic locations and features should allow confident differentiation between benign and malignant tumors.
  • Indicators of malignancy at MR imaging are invasive behavior, involvement of the right side of the heart or the pericardium, tissue inhomogeneity, diameter greater than 5 cm, and enhancement after administration of gadolinium contrast material (as a result of higher tissue vascularity).
  • Concomitant pericardial or pleural effusions are rare in benign processes but occur in about 50% of cases of malignant tumors.
  • MR imaging offers improved resolution, a larger field of view, and superior soft-tissue contrast compared with those of echocardiography, suggesting that knowledge of the MR imaging features of cardiac neoplasms is important for accurate diagnosis and management.
  • [MeSH-major] Heart Neoplasms / diagnosis. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Myxoma / diagnosis

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  • [Copyright] (c) RSNA, 2005.
  • (PMID = 16160110.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 84
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32. Hill M, Cherry C, Maloney M, Midyette P: Surgical resection of atrial myxomas. AORN J; 2010 Oct;92(4):393-406, quiz 407-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myxomas are the most common form of benign cardiac tumors; these tumors occur primarily in the atria.
  • Although these tumors are benign, myxomas have the potential to cause serious complications, including embolic events and partial or complete obstruction of intracardiac blood flow.
  • Currently, there is no effective medical treatment, and surgical excision of the tumor is necessary.
  • [MeSH-major] Heart Atria / pathology. Heart Neoplasms / surgery. Myxoma / surgery

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  • [Copyright] Copyright © 2010 AORN, Inc. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20888942.001).
  • [ISSN] 1878-0369
  • [Journal-full-title] AORN journal
  • [ISO-abbreviation] AORN J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Nemati MH, Astaneh B, Joubeh A: Cardiac hemangioma presenting with neurological manifestations. Gen Thorac Cardiovasc Surg; 2009 Mar;57(3):155-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac hemangioma presenting with neurological manifestations.
  • Primary cardiac tumors are rare.
  • Hemangiomas represent about 5%-10% of benign cardiac tumors.
  • Hemangiomas can be found in any heart chamber, but atria have been more frequently involved.
  • Hemangiomas may have various presentations, but there have been few reports about neurological manifestations of such tumors in the English-language literature.
  • [MeSH-major] Cerebrovascular Disorders / etiology. Heart Neoplasms / complications. Hemangioma / complications. Intracranial Embolism / etiology. Muscle Weakness / etiology. Speech Disorders / etiology
  • [MeSH-minor] Biopsy. Cardiac Surgical Procedures. Echocardiography. Heart Ventricles / pathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Treatment Outcome

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  • (PMID = 19280314.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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34. O'Donnell DH, Abbara S, Chaithiraphan V, Yared K, Killeen RP, Cury RC, Dodd JD: Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances. AJR Am J Roentgenol; 2009 Aug;193(2):377-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances.
  • OBJECTIVE: This article reviews the optimal cardiac MRI sequences for and the spectrum of imaging appearances of cardiac tumors.
  • CONCLUSION: Recent technologic advances in cardiac MRI have resulted in the rapid acquisition of images of the heart with high spatial and temporal resolution and excellent myocardial tissue characterization.
  • Cardiac MRI provides optimal assessment of the location, functional characteristics, and soft-tissue features of cardiac tumors, allowing accurate differentiation of benign and malignant lesions.
  • [MeSH-major] Heart Neoplasms / diagnosis. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adenomatous Polyposis Coli / diagnosis. Adult. Diagnosis, Differential. Endocardial Fibroelastosis / diagnosis. Female. Fibroma / diagnosis. Heart Diseases / diagnosis. Hemangioma / diagnosis. Humans. Lipoma / diagnosis. Lymphoma / diagnosis. Male. Middle Aged. Myxoma / diagnosis. Rhabdomyoma / diagnosis. Sarcoma / diagnosis. Thrombosis / diagnosis. Tuberous Sclerosis / diagnosis

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  • (PMID = 19620434.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 59
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35. Smith MA: Multiple synchronous atrial lipomas. Cardiovasc Pathol; 2007 May-Jun;16(3):187-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The incidence of primary tumors of the heart is low.
  • Three quarters of cardiac neoplasms are benign.
  • Cardiac lipomas are a mostly asymptomatic benign tumor that makes up less than 10% of primary heart tumors.
  • [MeSH-major] Heart Neoplasms / pathology. Lipoma / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Coronary Stenosis / etiology. Coronary Stenosis / pathology. Female. Heart Atria / pathology. Heart Atria / surgery. Humans. Middle Aged. Treatment Outcome. Tricuspid Valve / pathology

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  • (PMID = 17502250.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Seder CW, Sakwa MP, Shannon FL: Left ventricular myxoma resection with minimally invasive mitral valve reconstruction. J Heart Valve Dis; 2010 Jul;19(4):533-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ventricular myxomas are rare, accounting for less than 5% of all benign cardiac tumors.
  • Although histologically benign, myxomas can be a source of significant morbidity and mortality.
  • Precise preoperative imaging and surgical planning are necessary to achieve adequate tumor margins and to minimize the likelihood of recurrence.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Mitral Valve / surgery. Myxoma / surgery
  • [MeSH-minor] Adult. Chordae Tendineae / surgery. Female. Heart Ventricles / pathology. Heart Ventricles / surgery. Humans. Magnetic Resonance Imaging. Minimally Invasive Surgical Procedures. Neoplasm Invasiveness. Treatment Outcome

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  • (PMID = 20845903.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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37. Zerbo S, Argo A, Maresi E, Liotta R, Procaccianti P: Sudden death in adolescence caused by cardiac haemangioma. J Forensic Leg Med; 2009 Apr;16(3):156-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sudden death in adolescence caused by cardiac haemangioma.
  • Primary tumors of the heart in infants and children are rare.
  • The types of heart tumors in pediatric age groups are generally different from those in adults.
  • Cardiac myxoma is by far the most common tumor in adults, but in infants and adolescents the prevalent tumor of the heart is rhabdomyoma.
  • Among benign cardiac tumors, cardiac hemangiomas are rare and often diagnosed post-mortem due to the lack of specific clinical symptoms and signs.
  • We report a case of sudden death due to cardiac hemangioma in an apparently healthy 15-year-old adolescent.
  • The autopsy revealed a cardiac hemangioma located at the apex of the heart; the histopathological examination showed the tumor was a mixed capillary and arteriolar hemangioma, a very rare type of primary tumor in adolescents.
  • [MeSH-major] Death, Sudden / etiology. Heart Neoplasms / pathology. Hemangioma, Capillary / pathology

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  • (PMID = 19239968.001).
  • [ISSN] 1878-7487
  • [Journal-full-title] Journal of forensic and legal medicine
  • [ISO-abbreviation] J Forensic Leg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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38. Eftychiou C, Antoniades L: Cardiac hemangioma in the left ventricle and brief review of the literature. J Cardiovasc Med (Hagerstown); 2009 Jul;10(7):565-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac hemangioma in the left ventricle and brief review of the literature.
  • Cardiac hemangiomas are very rare benign cardiac tumors.
  • The natural history of these tumors is unpredictable.
  • Diagnosis is usually made with echocardiography and surgical resection is the treatment of choice.
  • Echocardiography revealed a mobile spherical mass within the left ventricle, whereas left ventriculography showed an intracavity-filling defect without any tumor blushing.
  • The tumor was removed surgically through the left atrium.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangioma, Capillary / pathology
  • [MeSH-minor] Adult. Cardiac Surgical Procedures. Echocardiography, Transesophageal. Heart Ventricles / pathology. Humans. Male. Treatment Outcome

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  • (PMID = 19424078.001).
  • [ISSN] 1558-2027
  • [Journal-full-title] Journal of cardiovascular medicine (Hagerstown, Md.)
  • [ISO-abbreviation] J Cardiovasc Med (Hagerstown)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 9
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39. Luna A, Ribes R, Caro P, Vida J, Erasmus JJ: Evaluation of cardiac tumors with magnetic resonance imaging. Eur Radiol; 2005 Jul;15(7):1446-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of cardiac tumors with magnetic resonance imaging.
  • Primary cardiac neoplasms are rare, and are more commonly benign than malignant.
  • However, metastases are by far the most common cardiac neoplasms.
  • MRI overcomes the usual limitations of echocardiography and assesses more accurately changes in cardiac function.
  • Suggestive features of malignancy are right side location, extracardiac extension, inhomogeneity in signal intensity of the tumor and pericardial effusion.
  • The use of intravenous contrast material improves tumor characterization and depiction of tumor borders.
  • MRI also allows differentiation of tumor from other nontumoral masses such as intracavitary tumors or fibromuscular elements of the posterior wall of the right atrium.
  • [MeSH-major] Heart Neoplasms / diagnosis. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Contrast Media. Humans. Image Enhancement / methods. Myocardium / pathology. Neoplasm Invasiveness. Pericardium / pathology

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  • [CommentIn] Eur Radiol. 2006 Aug;16(8):1858-9 [16583217.001]
  • (PMID = 15627179.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 33
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40. Farinelli A, Ferrara E, Cirillo M, Zorzi F: [Right ventricular cavernous hemangioma: a rare cardiac primary neoplasia]. Ital Heart J Suppl; 2005 Aug;6(8):498-501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Right ventricular cavernous hemangioma: a rare cardiac primary neoplasia].
  • [Transliterated title] Grosso emangioma cavernoso del ventricolo destro: una neoplasia primitiva cardiaca molto rara.
  • Primary neoplasia of the heart is rare and often diagnosed postmortem (with a prevalence < 0.2% at postmortem examinations) due to the lack of specific clinical symptoms and signs.
  • Among benign cardiac tumors, cavernous hemangioma has a prevalence of 2.8%.
  • Less invasive diagnostic techniques such as transthoracic echocardiography allow for the diagnosis to be made during life with definitive surgical treatment.
  • Surgical treatment was indicated for symptom severity and for the unpredictable behavior of the large neoplasm.
  • [MeSH-major] Heart Neoplasms. Hemangioma, Cavernous
  • [MeSH-minor] Aged. Diagnosis, Differential. Echocardiography. Female. Follow-Up Studies. Heart Ventricles. Humans. Radiography, Thoracic. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Ventricular Dysfunction, Right / diagnosis

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  • (PMID = 16161504.001).
  • [ISSN] 1129-4728
  • [Journal-full-title] Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology
  • [ISO-abbreviation] Ital Heart J Suppl
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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41. Canter RJ, Abt PL, Litzky LA, Frank A, Abt AB, Sellers MT, Markmann JF, Olthoff KM, Naji A, Shaked A: Successful liver, kidney, and pancreas transplantation from a donor with cerebral emboli from a left atrial myxoma. Transplant Proc; 2005 Dec;37(10):4334-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although atrial myxomas are benign cardiac tumors of stromal origin, they can lead to systemic embolization with ectopic myxoma formation.
  • [MeSH-minor] Adolescent. Heart Atria / pathology. Humans. Male


42. Tanrikulu MA, Ozben B, Cincin AA, Baskan O, Agirbasli M: A pedunculated left ventricular hemangioma initially misdiagnosed as thrombus in a woman with atypical chest pain. J Thromb Thrombolysis; 2009 Feb;27(2):227-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The incidence of cardiac masses increased as echocardiography is becoming increasingly popular.
  • Benign tumors of the heart constitute about 72% of all primary cardiac neoplasms and hemangioma accounts for 5-10% of benign cardiac tumors.
  • Cardiac hemangiomas are generally asymptomatic and diagnosed incidentally during echocardiography or magnetic resonance imaging (MRI).
  • With an initial diagnosis of left ventricular thrombus, the patient underwent cardiac MRI.
  • The mass was found compatible with cardiac hemangioma.
  • It was removed surgically and histopathologic evaluation identified a cardiac hemangioma.
  • As reports of cardiac hemangioma are extremely rare and cardiac masses are mostly thought to be thrombi or myxomas (being the most common primary cardiac tumor), such hemangioma cases warrant attention as possibility of hemangioma should also be kept in mind.
  • [MeSH-major] Diagnostic Errors. Heart Ventricles / pathology. Hemangioma / diagnosis. Thrombosis / diagnosis

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  • (PMID = 18246465.001).
  • [ISSN] 1573-742X
  • [Journal-full-title] Journal of thrombosis and thrombolysis
  • [ISO-abbreviation] J. Thromb. Thrombolysis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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43. Park HS, Park JH, Jeong JO: Intracoronary catheter aspiration can be an adequate option in patients with acute myocardial infarction caused by left atrial myxoma. J Cardiovasc Ultrasound; 2009 Dec;17(4):145-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac myxomas are the most common benign cardiac tumors and can be associated with systemic embolization including acute myocardial infarction (AMI).
  • The probability of an arterial embolization is closely related to a tumor's villous morphology.
  • In cases of AMI caused by cardiac myxoma, open heart surgery including excision of the coronary artery has been the one of the treatment options for removing the myxoma and embolus from the coronary artery to maintain distal coronary flow.
  • However, preparing for emergent open heart surgery takes a considerable amount of time.

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  • [Cites] Am J Cardiol. 1999 Jun 1;83(11):1579-82, A8 [10363879.001]
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  • (PMID = 20661341.001).
  • [ISSN] 2005-9655
  • [Journal-full-title] Journal of cardiovascular ultrasound
  • [ISO-abbreviation] J Cardiovasc Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2889398
  • [Keywords] NOTNLM ; Acute ST elevation myocardial infarction / Intracoronary aspiration / Myxoma
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44. Mueller OM, van de Nes JA, Wieland R, Schoch B, Sure U: Surgical treatment of primary intracranial myxoma in a child following radiotherapy: case report and review of the literature. Childs Nerv Syst; 2010 Jun;26(6):829-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Myxomas are benign tumors of the mesenchymal origin and account for about half of the benign cardiac tumors.
  • As a secondary neoplasia following radiotherapy, myxoma has only been reported once in the literature.
  • The close relation to the radiation field of the posterior fossa makes it highly suggestive that the myxoma developed as a secondary neoplasia induced by radiotherapy.
  • Treatment philosophy for this benign tumor entity is a completed resection of the lesion with regular follow-up MRI.
  • [MeSH-major] Brain Neoplasms / radiography. Brain Neoplasms / surgery. Medulloblastoma / radiotherapy. Myxoma / surgery. Neoplasms, Radiation-Induced / surgery
  • [MeSH-minor] Brain / pathology. Brain / surgery. Child. Combined Modality Therapy / methods. Disease Progression. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Time Factors

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  • (PMID = 19946690.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 32
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45. Fan D, Yarnall C, Parmet JL, Norris RB, Isidro AB, Maher MB, Bridges CR: Resection of a large atrial hemangioma using a bloodless surgical technique: a case report. Heart Surg Forum; 2007;10(1):E87-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangioma is extremely rare, accounting for 1% to 2% of benign cardiac tumors.
  • [MeSH-major] Heart Neoplasms / surgery. Hemangioma / surgery. Jehovah's Witnesses. Minimally Invasive Surgical Procedures / methods. Vascular Surgical Procedures / methods
  • [MeSH-minor] Aged. Female. Heart Atria / surgery. Humans. Treatment Outcome

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  • (PMID = 17311773.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Botha J, Ihlberg L, Elhenawy A, Abbott M, Butany J, Paul N, Brister SJ: A giant cavernous hemangioma of the heart. Ann Thorac Surg; 2010 Jul;90(1):293-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A giant cavernous hemangioma of the heart.
  • Cardiac hemangiomas are exceptionally rare, vascular neoplasms of the heart, with an incidence of 1% to 2% among all detected benign heart tumors.
  • With the availability of the advanced imaging modalities of the heart, asymptomatic cardiac tumors are detected more frequently.
  • These tumors are composed either of capillaries or larger cavernous channels.
  • Herein, we report a rare case of a huge cardiac hemangioma involving both ventricles, which is not amenable to a curative surgical resection.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangioma, Cavernous / diagnosis

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20609803.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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47. Irani AD, Estrera AL, Buja LM, Safi HJ: Biatrial myxoma: a case report and review of the literature. J Card Surg; 2008 Jul-Aug;23(4):385-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: In surgical series, a majority of benign cardiac tumors are myxomas.
  • METHODS: The tumor was removed surgically via a midline sternotomy using cardiopulmonary bypass.
  • Both left and right atrial extensions of the tumor mass were removed.
  • [MeSH-major] Heart Neoplasms / surgery. Myxoma / surgery
  • [MeSH-minor] Heart Atria. Humans. Male. Middle Aged

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  • (PMID = 18384573.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 35
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48. Wolf RC, Spiess J, Vasic N, Huber R: Valvular strands and ischemic stroke. Eur Neurol; 2007;57(4):227-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A filiform structure along the line of the aortic valve was first identified by transesophageal echocardiography, leading to the diagnosis of a valvular strand.
  • These masses are thought to represent giant Lambl's excrescences, although differential diagnoses include several benign cardiac tumors, e.g. papillary fibroelastoma.
  • [MeSH-major] Aortic Valve. Brain Ischemia / etiology. Heart Valve Diseases / complications. Stroke / etiology

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  • [Copyright] 2007 S. Karger AG, Basel
  • (PMID = 17312371.001).
  • [ISSN] 1421-9913
  • [Journal-full-title] European neurology
  • [ISO-abbreviation] Eur. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 34
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49. Alsaileek A, Tepe SM, Alveraz L, Miller DV, Tajik J, Breen J: Diagnostic features of cardiac hemangioma on cardiovascular magnetic resonance, a case report. Int J Cardiovasc Imaging; 2006 Oct;22(5):699-702
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic features of cardiac hemangioma on cardiovascular magnetic resonance, a case report.
  • Cardiac hemangiomas are benign cardiac tumors that account for 5-10% of all benign tumors of the heart (Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR.
  • They occur in any cardiac location, including the pericardium (Brodwater B, Erasmus J, McAdams HP, Dodd L.
  • This is a case report of cardiac hemangioma involving the ventricular septum with radiological and pathological correlation.
  • It illustrates the capability of the MRI to non-invasively detect histological and flow characteristics of the tumor.
  • [MeSH-major] Diffusion Magnetic Resonance Imaging. Heart Neoplasms / diagnosis. Hemangioma / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Female. Gadolinium. Heart Septum / pathology. Heart Ventricles / pathology. Humans. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 16705478.001).
  • [ISSN] 1569-5794
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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50. Bahnacy Y, Suresh C, Dawoud H, Zubaid M: Posterior left atrial wall hematoma mimicking cystic intracavitary atrial mass. Echocardiography; 2010 Oct;27(9):E102-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atrial myxoma is the most common benign primary tumor of the heart most commonly in the left atrium (LA).
  • Open-heart surgical exploration did not show any mass inside the LA.
  • Posterior left atrial wall hematoma may appear as left atrial intracavitary cystic mass and should be included in the differential diagnosis of cystic left atrial mass.
  • [MeSH-major] Cysts / ultrasonography. Echocardiography. Heart Diseases / ultrasonography. Hematoma / ultrasonography
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male

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  • [Copyright] © 2010, Wiley Periodicals, Inc.
  • (PMID = 20491860.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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51. Martínez Quesada M, Trujillo Berraquero F, Almendro Delia M, Hidalgo Urbano R, Cruz Fernández JM: [Cardiac hamartoma. Case report and literature review]. Rev Esp Cardiol; 2005 Apr;58(4):450-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac hamartoma. Case report and literature review].
  • Primary cardiac tumors are infrequent and usually benign.
  • They are sometimes an incidental finding in an asymptomatic patient.
  • The pathologic diagnosis was hamartoma of mature cardiac myocytes.
  • We discuss the usefulness of imaging techniques for identifying cardiac masses.
  • [MeSH-major] Hamartoma / diagnosis. Heart Diseases / diagnosis

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  • (PMID = 15847741.001).
  • [ISSN] 0300-8932
  • [Journal-full-title] Revista española de cardiología
  • [ISO-abbreviation] Rev Esp Cardiol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 13
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52. Yuce M, Dagdelen S, Ergelen M, Eren N, Caglar N: A huge obstructive myxoma located in the right heart without causing any symptom. Int J Cardiol; 2007 Jan 18;114(3):405-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A huge obstructive myxoma located in the right heart without causing any symptom.
  • Cardiac myxoma is unusual and mostly located in left atrium.
  • Although it is a benign tumor of the heart, it may cause life-threatening cardiac problems like valvular obstruction, systemic or pulmonary massive embolism, infection, arrhythmia, malignance.
  • We report a huge cardiac myxoma originated from right atrium.
  • [MeSH-major] Heart Neoplasms / diagnosis. Myxoma / diagnosis
  • [MeSH-minor] Auscultation. Diagnosis, Differential. Echocardiography. Heart Atria / pathology. Humans. Male. Middle Aged

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  • (PMID = 16626822.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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53. Reardon MJ, Malaisrie SC, Walkes JC, Vaporciyan AA, Rice DC, Smythe WR, DeFelice CA, Wojciechowski ZJ: Cardiac autotransplantation for primary cardiac tumors. Ann Thorac Surg; 2006 Aug;82(2):645-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac autotransplantation for primary cardiac tumors.
  • BACKGROUND: Complete tumor resection is the optimal treatment of cardiac tumors.
  • Anatomic accessibility and proximity to vital structures complicates resection of tumors involving the left heart.
  • The results of standard resection and resection with orthotopic heart transplantation are dismal.
  • We, therefore, reviewed our series of patients with complex left-sided primary cardiac tumors who underwent tumor resection with cardiac autotransplantation.
  • METHODS: Since April 1998, 11 consecutive patients with complex left atrial or left ventricular intracavitary cardiac tumors underwent 12 resections using cardiac autotransplantation-cardiac explantation, ex vivo tumor resection with cardiac reconstruction, and cardiac reimplantation.
  • Demographics, tumor histology, operative data, and mortality were analyzed.
  • RESULTS: Complete resection by cardiac autotransplantation was used in 7 patients with left atrial sarcoma, 1 patient with left ventricular sarcoma, 2 patients with left atrial paraganglioma, and 1 patient with a complex giant left atrial myxoma.
  • Eight patients had previous resection of their cardiac tumor, and 1 patient had a repeat autotransplantation for recurrent disease.
  • All patients with benign tumors are alive without evidence of recurrence.
  • CONCLUSIONS: Cardiac autotransplantation is a feasible technique for resection of complex left-sided cardiac tumors.
  • Recurrent disease after previous resections can be safely treated with this technique.
  • Benefits of this technique include improved accessibility and ability to perform a complete tumor resection with reliable cardiac reconstruction.
  • [MeSH-major] Heart Neoplasms / surgery. Heart Transplantation

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  • (PMID = 16863779.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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54. Han JS, An J, Yan DM: [Clinical analysis for 232 cases of primary heart neoplasms]. Zhonghua Wai Ke Za Zhi; 2006 Jan 15;44(2):87-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical analysis for 232 cases of primary heart neoplasms].
  • OBJECTIVE: To summarize the clinical characterizations and outcome of surgical treatment of primary heart neoplasms.
  • METHODS: The clinical data of cardiac neoplasms were analyzed retrospectively in 232 patients.
  • There were 14 malignant tumors (6.0%) and 218 benign tumors (94.0%), of which 200 were left atrial myxomas (86.2%).
  • Two hundred and twenty-three out of 230 patients underwent complete removal of the tumors, remaining 2 patients had partial removal.
  • One hundred and eighty-five cases were followed up for 6 months to 24 years, of which 10 malignant tumors died in 1 year and 1 malignant case recurred after 4 months.
  • Of 174 benign neoplasms, 1 case recurred and 10 cases were dead, remaining were cured.
  • CONCLUSIONS: Left atrial myxomas are most commonly seen in patients with primary heart neoplasms.
  • It is suggested that the patients should accept surgical treatment as soon as possible once the diagnosis is confirmed.
  • Surgical treatment is effective for the benign cardiac tumors.
  • Prognosis is poor in patients with malignant cardiac tumors.
  • [MeSH-major] Cardiac Surgical Procedures / methods. Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Myxoma / diagnosis. Myxoma / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Heart Valve Prosthesis Implantation. Humans. Male. Middle Aged. Mitral Valve / surgery. Pulmonary Valve / surgery. Retrospective Studies. Treatment Outcome

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  • (PMID = 16620663.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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55. Tutak E, Satar M, Ozbarlas N, Uğuz A, Yapicioğlu H, Narli N, Bayram I: A newborn infant with intrapericardial rhabdomyosarcoma: a case report. Turk J Pediatr; 2008 Mar-Apr;50(2):179-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac tumors are uncommon in neonates and most of them are histologically benign.
  • The most common cardiac tumor in neonates and infants is rhabdomyoma.
  • Malignant cardiac tumors are considerably rarer, and rhabdomyosarcoma (RMS) is the leading malignancy.
  • [MeSH-major] Heart Neoplasms / pathology. Rhabdomyosarcoma / pathology

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  • (PMID = 18664085.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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56. Dabek J, Twardowski R, Jakubowski D, Michniak B, Swiderski R, Gasior Z: [Effectiveness of heart tumor therapy in the cardiology department during 7 year follow-up]. Pol Merkur Lekarski; 2009 Nov;27(161):362-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effectiveness of heart tumor therapy in the cardiology department during 7 year follow-up].
  • [Transliterated title] Skuteczność leczenia guzów serca rozpoznanych w klinice kardiologii w siedmioletniej obserwacji.
  • Neoplasms of the heart are rare.
  • Among primary heart neoplasms the most often benign tumors are diagnosed--mostly myxomas, whereas the majority of malignant heart tumors are sarcomas.
  • The aim of this paper was to present heart tumors diagnosed in the cardiology department, their symptoms, used diagnostic tests and therapy and to show after therapy quality of life changes.
  • MATERIAL AND METHODS: There were 18 patients included to the study, whom during hospitalization in the cardiology department heart tumors were diagnosed.
  • There were 11 women and 7 men, aged from 33- to 76-years-old (mean 60,5 years).
  • RESULTS: Among 18 heart tumor patients in 12 cases primary benign tumors were diagnosed (66,6%), 1 patient had primary malignant tumor (5,5%), there were 3 cases of metastatic tumors (16,6%) and 2 patients with non-neoplasmic tumors--clots (11,1%).
  • From 18 subjects with heart tumor 3 patients died because of advanced stage of neoplasmic disease and presence of metastatic tumors in the heart.
  • CONCLUSIONS: Results of the study show, that heart tumors, regardless of development of diagnostic tests, are still diagnosed too late.
  • The study group follow-up proved, that early diagnosis and proper heart tumor treatment prevented complications and improved the quality of life.
  • It is worth to emphasize, that coronary angiogram in some cases allowed to diagnose coronary artery disease, to treat heart tumor and to perform coronary artery by-pass grafting simultaneously.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Delayed Diagnosis. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Quality of Life. Survival Rate

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  • (PMID = 19999797.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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57. Idahosa O, Mallavarapu V, Kostacos E: Papillary fibroelastoma arising from the left atrial free wall. J Am Soc Echocardiogr; 2007 Aug;20(8):1010.e1-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Primary cardiac tumors are rare.
  • Papillary fibroelastomas represent the second or third most common benign cardiac tumor and the most common one associated with heart valves.
  • Nonvalvular endocardial location of this tumor is extremely rare.
  • [MeSH-major] Fibroma / ultrasonography. Heart Atria / ultrasonography. Heart Neoplasms / ultrasonography

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  • (PMID = 17583477.001).
  • [ISSN] 1097-6795
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Ramana RK, Darki A, Havens M, Wojcik E, Brylka D, Singh MM, Leya F: Lipotamous cardiac disorders: two unsual cases and a review of the literature. J Invasive Cardiol; 2009 Apr;21(4):E65-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipotamous cardiac disorders: two unsual cases and a review of the literature.
  • Tumors involving the heart and surrounding cardiac structures may be benign or malignant and can be classified as primary versus secondary in etiology.
  • Primary cardiac tumors are rare lesions and the vast majority of these are benign neoplasms.
  • More commonly, masses that involve the cardiac structures are secondary in nature.
  • The focus of this manuscript will be those cardiac lesions characterized by a predominance of fatty cells.
  • We present two unusual cases of patients with lipomatous cardiac disorders with extreme imaging and review the current literature on this topic.
  • [MeSH-major] Cardiomyopathy, Hypertrophic / diagnosis. Heart Diseases / diagnosis. Heart Neoplasms / diagnosis. Lipomatosis / diagnosis

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  • (PMID = 19342764.001).
  • [ISSN] 1557-2501
  • [Journal-full-title] The Journal of invasive cardiology
  • [ISO-abbreviation] J Invasive Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
  • [Number-of-references] 36
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59. Fresneau B, Oberlin O, Brugières L, Valteau-Couanet D, Patte C: [Malignant primary cardiac tumors in childhood and adolescence]. Arch Pediatr; 2010 May;17(5):495-501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant primary cardiac tumors in childhood and adolescence].
  • [Transliterated title] Les tumeurs cardiaques primitives malignes de l'enfant et de l'adolescent.
  • Primary heart tumors are uncommon in children.
  • The majority of them are benign, with only 10% malignant.
  • Among malignant cardiac tumors, sarcoma (rhabdomyosarcoma, angiosarcoma, synovial sarcoma) and lymphoma (Burkitt's lymphoma, large B-cell lymphoma, lymphoblastic lymphoma) predominate.
  • There are few published pediatric series on malignant primary cardiac tumors.
  • We report here 3 observations of primary malignant cardiac tumors, 2 cases of sarcoma (angiosarcoma and synovial sarcoma) and 1 case of Burkitt's lymphoma.
  • A precise pathological diagnosis is necessary for the proper management of these patients.
  • Therefore, the prognosis of cardiac sarcoma remains poor.
  • For primary cardiac lymphoma, management should not be different from lymphoma in other locations.
  • [MeSH-major] Burkitt Lymphoma / diagnosis. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Sarcoma, Synovial / diagnosis
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Combined Modality Therapy. Cough / etiology. Diagnosis, Differential. Dyspnea / etiology. Echocardiography. Fatal Outcome. Female. Heart Atria / pathology. Heart Atria / surgery. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm, Residual / diagnosis. Neoplasm, Residual / pathology. Pulmonary Heart Disease / diagnosis. Pulmonary Heart Disease / etiology. Superior Vena Cava Syndrome / diagnosis. Superior Vena Cava Syndrome / etiology. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20338733.001).
  • [ISSN] 1769-664X
  • [Journal-full-title] Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
  • [ISO-abbreviation] Arch Pediatr
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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60. Vizzardi E, D'Aloia A, Chiari E, Nardi M, Zanini G, Cabras R, Faden G, Maiandi C, Cas LD: Tricuspid valve myxoma in a patient with congestive heart failure. Cases J; 2010;3:21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tricuspid valve myxoma in a patient with congestive heart failure.
  • Myxomas are the most frequent benign primary cardiac tumours (50% of benign heart tumours).
  • This kind of tumour is most likely to be localized in the left atrium, followed by the right atrium, right ventricle and left ventricle.

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  • (PMID = 20205805.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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61. Trisvetova EL: [Clinical diagnostics of papillary fibroelastoma]. Klin Med (Mosk); 2007;85(12):7-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Papillary fibroelastoma (PFE) is a benign heart tumor, the diagnosis of which is difficult.
  • Clinical manifestations of PFE are non-specific and scarce, and for this reason the tumor is often revealed during a heart surgery of an autopsy.
  • The histogenesis of the tumor is unclear; there are several theories of PFE origin (hemodynamic effects on the myocardium, viral theory, iatrogenic theory etc.
  • ) Macroscopically the tumor is small size, villous, whitish-grey, consists of a pedicle and villi of gely-like soft or dense-elastic consistence.
  • The mobility of the tumor and the fragmentation of its tissue lead to its main complications such as obstruction of cardiac cameras (in-flow and out-flow disorders) and embolic syndrome in various basins (the brain, coronary arteries, the eye, the kidneys, and the lungs).
  • The diagnosis of PFE is made using EchoCG, preferably transesophageal one.
  • Treatment of PFE is surgical and consists of tumor or cusp removal.
  • PFE should be differentiated from other benign and malignant heart tumors, infective endocarditis, heart echinococcosis, coronary artery disease, and cerebrovascular diseases.
  • [MeSH-major] Cardiac Surgical Procedures / methods. Fibroma. Heart Neoplasms. Ventricular Function / physiology
  • [MeSH-minor] Diagnosis, Differential. Echocardiography, Transesophageal. Humans. Papillary Muscles / pathology. Papillary Muscles / ultrasonography. Prognosis

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  • (PMID = 18318158.001).
  • [ISSN] 0023-2149
  • [Journal-full-title] Klinicheskaia meditsina
  • [ISO-abbreviation] Klin Med (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Russia (Federation)
  • [Number-of-references] 49
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62. Cusimano RJ: Surgical management of cardiac tumors. Semin Diagn Pathol; 2008 Feb;25(1):76-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of cardiac tumors.
  • Cardiac tumors, though rare, can affect all parts of the heart, from venous structures to atria to ventricles, valves, and great vessels.
  • Although most are benign and have good long-term prognosis, surgery for malignant tumors, whether primary or secondary, usually carries poor long-term survival.
  • Resection of ventricular tumors is limited by lack of a good ventricular muscular replacement.
  • Although cardiac transplantation has been used for tumors, long-term survival for anything but benign tumors is limited, making transplant a poor solution for any malignant tumors.
  • Outcome of resection of heart or great vessel tissue for tumors arising elsewhere is related more to the primary tumor than it is to the cardiac resection and reconstruction.
  • [MeSH-major] Heart Neoplasms / surgery

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  • (PMID = 18350926.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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63. Kim AY, Kim JS, Yoon Y, Kim EJ: Multidetector computed tomography findings of a papillary fibroelastoma of the aortic valve: a case report. J Korean Med Sci; 2010 May;25(5):809-12
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Papillary fibroelastoma is a rare benign cardiac tumor that represents 10% of all primary cardiac tumors.
  • Diagnosis is accomplished incidentally by echocardiography that is usually performed for another purpose.
  • [MeSH-major] Aortography / methods. Fibroma / radiography. Fibroma / surgery. Heart Neoplasms / radiography. Heart Neoplasms / surgery. Papillary Muscles / radiography. Papillary Muscles / surgery. Tomography, X-Ray Computed / methods

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  • (PMID = 20436724.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2858847
  • [Keywords] NOTNLM ; Aortic Valve / Echocardiography / Heart Neoplasms / Multidetector CT
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64. Company Campins MM, Antón E, Enríquez F, Palmer J, Serra JE, Bonnìn O: Cardiac papillary fibroelastoma in left ventricular apex. Cardiovasc Pathol; 2007 Sep-Oct;16(5):317-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac papillary fibroelastoma in left ventricular apex.
  • Papillary fibroelastoma (PF) is a rare benign heart tumor and represents less than 10% of primary cardiac tumors.
  • It mainly affects the cardiac valves and is often discovered during open heart surgery or autopsy.
  • We present a case of a patient who was detected with a left ventricular apex tumor during the evaluation of the transient ischemic attack.
  • The patient underwent surgery, and subsequently, macroscopic and microscopic examination confirmed the diagnosis of PF.
  • [MeSH-major] Heart Neoplasms / diagnosis. Incidental Findings. Neoplasms, Fibrous Tissue / diagnosis
  • [MeSH-minor] Cardiac Surgical Procedures. Heart Ventricles / pathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17868885.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Aggarwal M, Sachan R, Arya S, Chellani H: Cardiac rhabdomyoma--a case report. J Trop Pediatr; 2010 Oct;56(5):345-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac rhabdomyoma--a case report.
  • Cardiac tumors are rare in neonates, most are benign hamartomas (rhabdomyomas) of the muscle cells.
  • [MeSH-major] Heart Neoplasms / complications. Rhabdomyoma / complications

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  • (PMID = 20093353.001).
  • [ISSN] 1465-3664
  • [Journal-full-title] Journal of tropical pediatrics
  • [ISO-abbreviation] J. Trop. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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66. Alghamdi AA, Sheth T, Manowski Z, Djoleto OF, Bhatnagar G: Utility of cardiac CT and MRI for the diagnosis and preoperative assessment of cardiac paraganglioma. J Card Surg; 2009 Nov-Dec;24(6):700-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of cardiac CT and MRI for the diagnosis and preoperative assessment of cardiac paraganglioma.
  • BACKGROUND: Cardiac paragangliomas are rare cardiac tumors that are usually benign.
  • METHODS: We report a case of 39-year-old male who, during the work up of acute coronary syndrome with coronary angiography, cardiac computed tomography (CT) and magnetic resonance imaging (MRI), was found to have cardiac paraganglioma.
  • RESULTS: The tumor was intrapericardial, arising at the level of proximal left anterior descending artery.
  • The tumor was completely resected and the postoperative course was uneventful.
  • CONCLUSION: Cardiac CT and MRI are valuable in characterizing and preoperative planning of primary cardiac paragangliomas.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Magnetic Resonance Imaging. Paraganglioma / diagnosis. Paraganglioma / surgery. Tomography, X-Ray Computed
  • [MeSH-minor] Acute Coronary Syndrome / diagnosis. Adult. Atrial Appendage / pathology. Atrial Appendage / surgery. Coronary Angiography. Diagnosis, Differential. Heart Ventricles / pathology. Heart Ventricles / surgery. Humans. Male. Postoperative Complications / diagnosis

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  • (PMID = 19682163.001).
  • [ISSN] 1540-8191
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Amonkar GP, Deshpande JR: Cardiac angiosarcoma. Cardiovasc Pathol; 2006 Jan-Feb;15(1):57-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma.
  • Primary tumors of the heart are extremely rare, with a prevalence rate of around 0.01% in collective autopsy studies.
  • Majority of the primary cardiac tumors are benign.
  • Myxoma is the most common primary cardiac tumor, while angiosarcoma is the commonest primary malignant tumor.
  • A complete autopsy was performed and a diagnosis of cardiac angiosarcoma was confirmed on histology and immunohistochemistry.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / secondary
  • [MeSH-minor] Adult. Fatal Outcome. Heart Atria / pathology. Humans. Immunohistochemistry. Lung Neoplasms / secondary. Male

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  • (PMID = 16414459.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Alurkar VM, Neupane S: Two interesting cases of left atrial myxoma. Kathmandu Univ Med J (KUMJ); 2010 Jan-Mar;8(29):80-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atrial myxoma is the most common type of benign primary heart tumours.
  • Most of these tumours are sporadic in origin occurring at 3rd to 6th decade of life, while hereditary forms do exist.
  • A left atrial myxoma may present with features of mitral valve obstruction, embolic phenomenon or systemic disease.
  • On diagnosis, prompt surgical removal is necessary which usually gives a complete cure, though recurrences have been reported.
  • [MeSH-major] Heart Neoplasms / diagnosis. Myxoma / diagnosis
  • [MeSH-minor] Adolescent. Aged. Diagnosis, Differential. Female. Heart Atria. Humans

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  • (PMID = 21209512.001).
  • [ISSN] 1812-2078
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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69. Maxey TS, Grow P, Morris CD, Patton KT, Guyton RA: Biatrial primary cardiac paraganglioma: a rare finding. Cardiovasc Pathol; 2007 May-Jun;16(3):179-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biatrial primary cardiac paraganglioma: a rare finding.
  • The majority of primary cardiac tumors are benign; of these tumors, cardiac paragangliomas are among the rarest.
  • We report a case of biatrial cardiac paraganglioma discovered during workup for palpitations and fatigue.
  • The tumor involved the interatrial septum, with a lobulated portion protruding through the foramen ovale into the right atrium.
  • The tumor was successfully excised, leading to uneventful recovery.
  • [MeSH-major] Heart Neoplasms / pathology. Paraganglioma / pathology
  • [MeSH-minor] Adult. Echocardiography, Transesophageal. Heart Atria / pathology. Heart Atria / surgery. Heart Septum / pathology. Heart Septum / surgery. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17502248.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Amonkar GP, Kandalkar BM, Balasubramanian M: Cardiac rhabdomyoma. Cardiovasc Pathol; 2009 Sep-Oct;18(5):313-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac rhabdomyoma.
  • Primary tumors of the heart are exceedingly rare with a prevalence rate of around 0.01% in autopsy studies.
  • A majority of primary cardiac tumors are benign.
  • Rhabdomyomas are the most common of benign pediatric cardiac tumors.
  • The infant expired, and at autopsy, dissection of the heart revealed a large tumor mass in the interventricular septum.
  • Histologically, the mass showed the classic "spider cells," and a diagnosis of cardiac rhabdomyoma of childhood was established.
  • [MeSH-major] Heart Neoplasms / pathology. Rhabdomyoma / pathology

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  • (PMID = 18417369.001).
  • [ISSN] 1879-1336
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Thielke D, Thyssen JP, Sejersen HM: [Cardiac myxoma--a rare cause of cerebral embolism]. Ugeskr Laeger; 2008 Aug 11;170(33):2460
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac myxoma--a rare cause of cerebral embolism].
  • Cardiac myxoma is the most common benign heart tumor.
  • We report a case with multiple brain metastases, presumably due to tumor embolization.
  • It is important to perform transthoracic echocardiography at a very early stage to exclude structural heart disease in patients with signs of multiple brain metastases.
  • Though myxoma is a rare cause of cerebral embolism, detection of this tumor is relatively easy and surgical resection of myxoma is usually a permanent measure to prevent subsequent stroke.
  • [MeSH-major] Brain Neoplasms / complications. Heart Neoplasms / complications. Intracranial Embolism / etiology. Myxoma / complications
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Stroke / prevention & control

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  • (PMID = 18761832.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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72. Goldberg SP, Knott-Craig CJ, Boston US, Mari GC, Colvin EV, Chin TK: Surgical management of unusual cardiac tumors in infants and children. World J Pediatr Congenit Heart Surg; 2010 Jul;1(2):211-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of unusual cardiac tumors in infants and children.
  • While most primary tumors of the heart are histologically benign, they are significant space-occupying lesions with serious functional implications for the heart and lungs.
  • Herein, we highlight our experience with the surgical management of selected cardiac tumors in the pediatric population between 2008 and 2010. (1) Intrapericardial teratomas in the fetus can produce fatal tamponade from compression by the attendant pericardial effusion, and a critical life-saving maneuver preoperatively is to drain the effusion prenatally, followed by an expeditious resection after birth. (2) Rhabdomyomas, the most common of the pediatric cardiac tumors, can be intracavitary, large, and associated with the mitral subvalvular apparatus. (3) Cardiac fibromas should be aggressively resected or at least debulked, especially given their propensity for dysrrhythmias.

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  • (PMID = 23804823.001).
  • [ISSN] 2150-1351
  • [Journal-full-title] World journal for pediatric & congenital heart surgery
  • [ISO-abbreviation] World J Pediatr Congenit Heart Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; cardiac tumor / child / infant
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73. Zhou WX, Wang H, Ruan YM, Yan J, Wei YZ, Liu YL: [Diagnostic value of echocardiography for cardiac tumors in infancy and childhood]. Zhonghua Er Ke Za Zhi; 2005 Oct;43(10):758-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnostic value of echocardiography for cardiac tumors in infancy and childhood].
  • OBJECTIVE: The present study was designed to evaluate the clinical manifestations, surgical findings, pathologic types and treatment of cardiac tumor and to analyze the echocardiographic characteristics of the cases.
  • METHODS: Records of 19 patients with cardiac tumors confirmed by operations and pathology at Fuwai Cardiovascular Hospital in Beijing, China between Jan, 1983 and Dec, 2003 were reviewed.
  • The surgical findings revealed that 57.9% (11 cases) of cardiac tumors were found in left heart, 36.8% (7 cases) in right heart, 5.3% (1 case) in two ventricles.
  • The pathological study revealed that 17 cases (89.5%) were diagnosed as primary cardiac benign tumors including myxoma in 10 cases (52.6%), rhabdomyoma in 4 cases (21.1%), fibroma in 2 cases (10.5%) and lipoma in 1 case (5.3%).
  • Two cases were diagnosed (10.5%) as cardiac malignant tumors including a primary cardiac rhabdomyosarcoma and a metastatic epithelioid sarcoma.
  • By using echocardiography 11 cases were diagnosed as myxomas and rhabdomyoma (11/19, 57.9%), 8 cases were diagnosed as space occupying lesions of the heart or myxoma (8/19, 42.1%).
  • CONCLUSIONS: Myxomas are the most common heart tumors seen in infancy and childhood, followed in frequency by rhabdomyomas, fibromas and lipomas.
  • [MeSH-major] Echocardiography. Heart Neoplasms / ultrasonography

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  • (PMID = 16255855.001).
  • [ISSN] 0578-1310
  • [Journal-full-title] Zhonghua er ke za zhi = Chinese journal of pediatrics
  • [ISO-abbreviation] Zhonghua Er Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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74. Miller DV, Tazelaar HD: Cardiovascular pseudoneoplasms. Arch Pathol Lab Med; 2010 Mar;134(3):362-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Primary cardiac tumors are rare and the great majority are benign neoplasms.
  • Mass-forming reactive and pseudoneoplastic growths are less common, but recognizing and distinguishing these lesions from the neoplasms they resemble is critical to appropriate patient care.
  • OBJECTIVE: The general clinical, imaging, gross pathologic, and histologic features of 5 important pseudoneoplasms (inflammatory myofibroblastic tumor, hamartoma of mature cardiac myocytes, mesothelial/monocytic cardiac excrescences, calcified amorphous tumor, and lipomatous hypertrophy of the atrial septum) are discussed, with an emphasis on features differentiating them from other benign and malignant tumors.
  • [MeSH-major] Granuloma, Plasma Cell / pathology. Heart Diseases / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male

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  • [CommentIn] Arch Pathol Lab Med. 2010 Nov;134(11):1584-6 [21043810.001]
  • (PMID = 20196664.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 37
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75. Venturini E, Magni L, Franchini C, Testa R: Right atrial hemangioma. J Cardiovasc Med (Hagerstown); 2008 Dec;9(12):1260-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hemangiomas are rare benign neoplasms of the heart generally diagnosed in young or middle-aged patients.
  • We report a case of asymptomatic 71-year-old-woman in whom the tumor was detected after an echocardiogram.
  • Echocardiography directs the diagnosis toward a cardiac mass but some aspects can suggest the hemangioma; MRI and coronary arteriography establishes the diagnosis showing the typical tumor blush.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangioma / diagnosis
  • [MeSH-minor] Aged. Coronary Angiography. Echocardiography. Female. Heart Atria. Humans. Magnetic Resonance Imaging

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  • (PMID = 19001934.001).
  • [ISSN] 1558-2027
  • [Journal-full-title] Journal of cardiovascular medicine (Hagerstown, Md.)
  • [ISO-abbreviation] J Cardiovasc Med (Hagerstown)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Jallad N, Parikh R, Daoko J, Albareqdar E, Al-Dehneh A, Goldstein J, Shamoon F, Connolly MW: Concurrent primary cardiac tumors of differing histology and origin: case report with literature review. Tex Heart Inst J; 2009;36(6):591-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent primary cardiac tumors of differing histology and origin: case report with literature review.
  • Primary cardiac tumors are rare and are diverse in histology and anatomic origin.
  • Approximately 75% are benign, and nearly 50% of these are myxomas.
  • Herein, we report concurrent myxoma and papillary fibroelastoma, which tumors were found attached to the left atrial septum and aortic valve, respectively.
  • Concurrent primary cardiac tumors of differing histology and origin are rare, and, to our knowledge, this is one of the few such cases reported in the medical literature.

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  • (PMID = 20069087.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
  • [Other-IDs] NLM/ PMC2801934
  • [Keywords] NOTNLM ; Echocardiography / fibroma / heart neoplasms/primary/diagnosis/surgery / myxoma / neoplasms, multiple primary/diagnosis/surgery
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77. Yinon Y, Chitayat D, Blaser S, Seed M, Amsalem H, Yoo SJ, Jaeggi ET: Fetal cardiac tumors: a single-center experience of 40 cases. Prenat Diagn; 2010 Oct;30(10):941-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fetal cardiac tumors: a single-center experience of 40 cases.
  • OBJECTIVE: To determine the natural history and outcome of fetal cardiac tumors.
  • METHODS: This was a retrospective cohort study of all prenatally detected cases of cardiac tumors at a tertiary cardiac care center.
  • RESULTS: Forty fetuses were identified to have one or several cardiac tumors in association with fetal hydrops (18%), ventricular obstruction (30%) and/or arrhythmia (13%).
  • On follow-up, 95% of all live-born cases with rhabdomyomas were free of cardiac symptoms but 88% had tuberous sclerosis.
  • In contrast, all three fetuses with cardiac fibroma are alive and have a biventricular physiology.
  • Fetal or neonatal death was associated with an earlier cardiac anomaly diagnosis, earlier delivery, larger tumor size and fetal hydrops at presentation.
  • CONCLUSIONS: The outcome of fetal cardiac tumors was predicted by the etiology and size of the cardiac mass and the presence of hydrops.
  • Although most cardiac rhabdomyomas have a relatively benign perinatal course, the long-term prognosis is determined by the neurological manifestations associated with tuberous sclerosis.
  • [MeSH-major] Fetal Diseases / pathology. Fetal Heart / pathology. Heart Neoplasms / pathology. Rhabdomyoma / pathology. Ultrasonography, Prenatal
  • [MeSH-minor] Adult. Arrhythmias, Cardiac / epidemiology. Arrhythmias, Cardiac / etiology. Arrhythmias, Cardiac / pathology. Canada / epidemiology. Cohort Studies. Echocardiography. Female. Gestational Age. Humans. Hydrops Fetalis / epidemiology. Hydrops Fetalis / etiology. Hydrops Fetalis / pathology. Pregnancy. Retrospective Studies. Ventricular Outflow Obstruction / epidemiology. Ventricular Outflow Obstruction / etiology. Ventricular Outflow Obstruction / pathology

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  • [Copyright] © 2010 John Wiley & Sons, Ltd.
  • (PMID = 20721876.001).
  • [ISSN] 1097-0223
  • [Journal-full-title] Prenatal diagnosis
  • [ISO-abbreviation] Prenat. Diagn.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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78. Paramés F, Freitas I, Martins JD, Trigo C, Pinto MF: Cardiac tumors: the 17-year experience of pediatric cardiology department. Rev Port Cardiol; 2009 Sep;28(9):929-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tumors: the 17-year experience of pediatric cardiology department.
  • INTRODUCTION: Primary cardiac tumork may be benign or malignant and may arise anywhere in the endocardium, myocardium or pericardium.
  • They are rare in pediatric age-groups, with a prevalence in autopsy findings of 0.0017 to 0.28%; most are benign, malignant tumors accounting for only 10% of the total.
  • OBJECTIVE AND METHODS: The purpose of this paper is to report the 17-year (1989-2006) experience of primary cardiac tumors in a single center.
  • RESULTS: We identified 12 patients, with a mean age at diagnosis of 23 months, in two cases diagnosed in the fetal period.
  • The frequent cause of referral was tuberous sclerosis, followed by a cardiac murmur.
  • The diagnosis of primary cardiac tumor was based on echocardiography and/or magnetic resonance imaging.
  • The patients all underwent 24-hour electrocardiographic Holter monitoring, and the most common finding was nonspecific repolarization abnormalities.
  • The most frequent cardiac tumor was rhabdomyoma (67%), usually associated with tuberous sclerosis, followed by fibroma (17%) and fibroelastoma (8%) Although biopsy is the diagnostic gold standard, it was only performed in two patients.
  • Surgical removal of the tumor was performed in a single patient (with fibroelastoma) due to the perceived risk of pulmonary embolization.
  • DISCUSSION AND CONCLUSIONS: In our population, the most frequent tumor was rhabdomyoma associated with tuberous sclerosis.
  • Most patients were asymptomatic, and the diagnosis was made in routine observations on patients with tuberous sclerosis or with a cardiac murmur.
  • A histopathological diagnosis is only warranted in the rarest forms of cardiac tumors.
  • [MeSH-major] Heart Neoplasms

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  • (PMID = 19998805.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Portugal
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79. Altundag MB, Ertas G, Ucer AR, Durmus S, Abanuz H, Calikoğlu T, Ozbagi K, Demirkasimoglu A, Kaya B, Bakkal BH, Altundag K: Brain metastasis of cardiac myxoma: case report and review of the literature. J Neurooncol; 2005 Nov;75(2):181-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brain metastasis of cardiac myxoma: case report and review of the literature.
  • Cardiac myxoma is the most common benign heart tumor.
  • Cardiac myxoma can be a sporadic lesion (93% of cases) and usually occurs in women over 30 years.
  • Complete surgical removal of the myxoma and its cardiac attachment is usually curative.
  • The frequency of recurrences in cardiac myxomas varies between 3% for sporadic cases and 22% for cases of Carney complex.
  • Recurrence has been related to incomplete excision, multifocality, and embolism of tumor fragments.
  • We report a case with multiple brain metastases presumably due to tumor embolization from previously operated cardiac myxoma.
  • [MeSH-major] Brain Neoplasms / secondary. Heart Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 16132507.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 38
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80. Giuşcă S, Jurcuţ R, Serban M, Popescu BA, Apetrei E, Ginghină C: Cardiac tumors: the experience of a tertiary cardiology center. Rom J Intern Med; 2007;45(4):333-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tumors: the experience of a tertiary cardiology center.
  • Cardiac tumors represent a rare condition, often presenting with severe symptoms and having a poor outcome in the absence of early diagnosis and therapy.
  • The aim of this study was to assess the prevalence and type of cardiac tumors, the techniques used for the diagnosis and the therapy used in a tertiary cardiology center.
  • RESULTS: In the CTum group (49 +/- 16.2 years, similar between men and women), the main symptoms leading to patients referral were dyspnea (15 pts, 62.5%) and embolic events (coronary, cerebral, peripheral arteries: 7 pts, 29%), while in 4 asymptomatic pts the diagnosis was incidental.
  • In 20 pts (83%), TTE and transesophageal echocardiography (TEE) provided all the data required for preoperative assessment (tumor size, extension, location, insertion site).
  • In 4 pts, additional CT and MRI investigations were necessary, mainly for complex disease (malignant secondary CTum).
  • The imaging techniques suggested a diagnosis of benign tumor in 15 pts (62.5%) and malignant tumor in 5 pts.
  • In 4 pts the tumor type could not be established.
  • Myxoma was the most frequent diagnosis (14 pts, 58% CTum).
  • Among malignant CTum, secondary tumors (melanoma, lung and uterine cancer) were more frequent than primary CTum (4 vs 1 pt).
  • Surgery was performed in 18 pts, confirming the preoperative diagnosis in 17 cases (94%).
  • In one case, a myxochondrosarcoma was diagnosed at pathology in a patient with an echocardiography-based preoperative diagnosis of myxoma.
  • Echocardiography (TTE and TEE) is the essential imaging modality, allowing in most cases the diagnosis, classification and localization of CTum and their insertion site.
  • In the case of benign tumors, surgery must be performed as soon as possible after the diagnosis has been established, whereas for malignant tumors there is still much controversy in what regards the benefits of surgery.
  • [MeSH-major] Echocardiography, Transesophageal. Heart Neoplasms / ultrasonography

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  • (PMID = 18767408.001).
  • [ISSN] 1220-4749
  • [Journal-full-title] Romanian journal of internal medicine = Revue roumaine de médecine interne
  • [ISO-abbreviation] Rom J Intern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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81. Bicer M, Cikirikcioglu M, Pektok E, Müller H, Dettwiler S, Kalangos A: Papillary fibroelastoma of the left atrial wall: a case report. J Cardiothorac Surg; 2009;4:28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac papillary fibroelastoma is a rare, benign cardiac tumor.
  • Although transthoracic echocardiography is usually sufficient for the diagnosis of most cardiac tumors, small tumors such as papillary fibroelastoma may be missed.
  • Transesophageal echocardiography is superior to transthoracic echocardiography in diagnosing these tumors.
  • Despite their benign histology, and independent of their size, they should be resected surgically because of their high potential for embolization.
  • Pertinent literature is also reviewed for this rare and benign cardiac tumor.
  • [MeSH-major] Brain Ischemia / etiology. Fibroma / complications. Fibroma / surgery. Heart Neoplasms / complications. Heart Neoplasms / surgery
  • [MeSH-minor] Aged. Echocardiography, Transesophageal. Heart Atria / pathology. Heart Atria / surgery. Heart Atria / ultrasonography. Humans. Male

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  • [Cites] J Heart Valve Dis. 2000 Nov;9(6):832-41 [11128794.001]
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  • (PMID = 19570232.001).
  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 15
  • [Other-IDs] NLM/ PMC2715399
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82. Arnaiz G P, Toledo G I, Borzutzky S A, Urcelay M G, Heusser R F, Garay G F, Castillo N E, Toro R L, Becker R P, Arretz V C, Córdova A S: [Cardiac tumors in children and adults: A Multicentric retrospective study]. Rev Med Chil; 2006 Sep;134(9):1135-45

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac tumors in children and adults: A Multicentric retrospective study].
  • [Transliterated title] Comportamiento clínico de los tumores cardíacos desde el feto hasta el adulto: serie multicéntrica de 38 pacientes.
  • BACKGROUND: Cardiac tumors are very uncommon at all ages.
  • There are important clinical differences between children and adults in the behavior of these tumors.
  • AIM: To compare the behavior of primary and secondary cardiac tumors, from fetal age to adults.
  • PATIENTS AND METHOD: Multicentric retrospective analysis of 38 children and adults with cardiac tumors, evaluated with echocardiography between January 1995 and August 2001.
  • RESULTS: Tumors were diagnosed in 38 patients (13 children and 25 adults), from a total of 31.800 echocardiograms.
  • In children the diagnosis was made by fetal, transthoracic or transesophageal echocardiography in 23.6% and 8% of cases, respectively.
  • Eighty five percent were primary (10 benign and 1 malignant) and 15%, secondary tumors.
  • In adults, 76% of tumors were diagnosed by transthoracic and 20% by transesophageal echocardiography.
  • Seventy six percent were primary (18 benign and 1 malignant) and 24% secondary tumors.
  • In adults, myxomas are the predominant cardiac tumors.
  • Primary and metastasic malignant tumors are observed both in children and in adults.
  • [MeSH-major] Heart Neoplasms / ultrasonography. Rhabdomyoma / ultrasonography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Chile / epidemiology. Echocardiography. Female. Fetal Heart / ultrasonography. Fibroma / epidemiology. Fibroma / ultrasonography. Follow-Up Studies. Humans. Infant. Infant, Newborn. Male. Middle Aged. Myxoma / epidemiology. Myxoma / ultrasonography. Pregnancy. Retrospective Studies. Ultrasonography, Prenatal

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  • (PMID = 17171215.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Chile
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83. Chaowalit N, Dearani JA, Edwards WD, Pellikka PA: Calcified right ventricular mass and pulmonary embolism in a previously healthy young woman. J Am Soc Echocardiogr; 2005 Mar;18(3):275-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is postulated that its development was related to cardiac trauma.
  • These intracavitary masses have been referred to as cardiac calcified amorphous tumors and generally represent old organized and focally calcified mural thrombus.
  • They should be distinguished from calcified benign or malignant neoplasms of the heart.
  • [MeSH-major] Calcinosis / ultrasonography. Heart Diseases / ultrasonography. Pulmonary Embolism / complications. Thrombosis / ultrasonography
  • [MeSH-minor] Echocardiography. Female. Heart Ventricles / surgery. Heart Ventricles / ultrasonography. Humans

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  • (PMID = 15746720.001).
  • [ISSN] 0894-7317
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Coley C, Lee KR, Steiner M, Thompson CS: Complete embolization of a left atrial myxoma resulting in acute lower extremity ischemia. Tex Heart Inst J; 2005;32(2):238-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atrial myxoma is the most common benign tumor of the heart.
  • Patients who have atrial myoxmas usually present with cardiac obstruction, arrhythmias, or peripheral embolization.
  • A tumor originating in the left atrium most often embolizes to the cerebrovascular system.

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  • (PMID = 16107126.001).
  • [ISSN] 0730-2347
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1163484
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85. Mariano A, Pita A, León R, Rossi R, Gouveia R, Teixeira A, Ferreira R, Anjos R, Menezes I, Martins FM: Primary cardiac tumors in children: a 16-year experience. Rev Port Cardiol; 2009 Mar;28(3):279-88

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac tumors in children: a 16-year experience.
  • INTRODUCTION: Primary cardiac tumors are rare in children.
  • The majority are benign and noninvasive, although they may have significant hemodynamic consequences depending on their location.
  • OBJECTIVES: To assess the presentation and outcome of patients with cardiac tumors followed by the Department of Pediatric Cardiology of Hospital de Santa Cruz.
  • METHODS: A retrospective analysis was performed of the clinical records of patients diagnosed with primary cardiac tumors between January 1992 and March 2008.
  • RESULTS: Eleven children with a diagnosis of primary cardiac tumor were identified, three of them detected antenatally.
  • In the remaining cases, median age at diagnosis was 27.5 months, ranging from two days to 13 years.
  • In three cases diagnosis was made during fetal echocardiography, and in the others by transthoracic echocardiogram.
  • In six patients magnetic resonance imaging was used to confirm the diagnosis.
  • All were benign (eight rhabdomyomas, one papillary fibroelastoma, one myxoma and one pericardial tumor with histological features of Castleman disease).
  • Six patients were asymptomatic at the time of diagnosis; two cases presented with arrhythmias; one with heart failure; and two were diagnosed following stroke, one with right hemiparesis, and the other with paresthesias of the lip and fingers of the right hand.
  • In four cases there was total or partial tumor regression.
  • Surgery was performed in four patients, due to tumor location and/ or significant left ventricular outflow tract obstruction.
  • FINAL REMARKS: Primary cardiac tumors are uncommon in children.
  • [MeSH-major] Heart Neoplasms

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  • (PMID = 19480311.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Portugal
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86. Rohani A, Akbari V: A colossal atrial myxoma. J Cardiovasc Dis Res; 2010 Jul;1(3):158-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Atrial myxomas are the most common benign primary tumor of the heart.
  • These cardiac growths can masquerade as mitral stenosis and infective endocarditis.
  • Excision revealed a 14 × 8 × 6 cm3 tumor attached to a 4 × 3 × 2 cm3 stalk of septal tissue.

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  • (PMID = 21187871.001).
  • [ISSN] 0976-2833
  • [Journal-full-title] Journal of cardiovascular disease research
  • [ISO-abbreviation] J Cardiovasc Dis Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2982205
  • [Keywords] NOTNLM ; Hypesthesia / myxomas / vertigo
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87. Veinot JP: Cardiac tumors of adipocytes and cystic tumor of the atrioventricular node. Semin Diagn Pathol; 2008 Feb;25(1):29-38
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac tumors of adipocytes and cystic tumor of the atrioventricular node.
  • Lipomatous lesions of the heart and cystic tumor of the atrioventricular node are not common.
  • A pathologist will only rarely encounter these entities, and in the case of the atrioventricular node tumor, only if they examine the conduction system.
  • Most fatty lesions are not clinically significant; however, arrhythmias, blood flow obstruction, and valvular dysfunction may result from benign or malignant lipomatous tumors.
  • Cystic tumor of the atrioventricular node has been implicated in the causation of sudden cardiac death, and there has been much academic interest concerning its cell of origin.
  • [MeSH-major] Adipocytes / pathology. Atrioventricular Node / pathology. Heart Neoplasms / pathology. Neoplasms, Adipose Tissue / pathology

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  • (PMID = 18350920.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Sydow K, Willems S, Reichenspurner H, Meinertz T: Papillary fibroelastomas of the heart. Thorac Cardiovasc Surg; 2008 Feb;56(1):9-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary fibroelastomas of the heart.
  • Cardiac papillary fibroelastomas (CPFs), the second most common primary cardiac tumor, are benign endocardial papillomas predominantly affecting the cardiac valves.
  • Although CPFs are rare and benign tumors, they may result in life-threatening complications.
  • Early diagnosis of this condition is important, since it represents a surgically correctable cause of systemic embolism, myocardial infarction, stroke, acute valve dysfunction, and sudden cardiac death.
  • This review summarizes the significance and clinical approach for the diagnosis of this cardiac entity.
  • The differential diagnosis, histological characteristics of CPF and current treatment strategies are also discussed.
  • [MeSH-major] Fibroma. Heart Neoplasms
  • [MeSH-minor] Diagnosis, Differential. Heart Valves. Humans

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  • (PMID = 18200460.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 77
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89. Türkoglu H, Alkan T, Okçün B, Akçevin A, Paker T, Ersoy C, Sasmazel A, Aytaç A: Symptomatic lipoma in the interventricular septum. ASAIO J; 2006 Nov-Dec;52(6):e35-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac lipomas, which are benign nonmyxomatous neoplasms of the heart, are rare and among those least often encountered.
  • Because they normally cause no symptoms, diagnosis is often purely accidental.
  • Transthoracic and transesophageal echocardiograms were performed and showed a mass in the left side of the Ivs. During successful surgical excision of the mass, intraoperative histologic diagnosis showed the tumor was lipoma.
  • Our review of the English literature revealed that our case is only the seventh of removal of lipoma in the Ivs. The postoperative course was uneventful, and an echocardiogram taken 6 months after the operation showed no evidence of enlargement of the tumor tissue.
  • [MeSH-major] Heart Neoplasms / pathology. Heart Septum / pathology. Lipoma / pathology

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  • (PMID = 17117044.001).
  • [ISSN] 1538-943X
  • [Journal-full-title] ASAIO journal (American Society for Artificial Internal Organs : 1992)
  • [ISO-abbreviation] ASAIO J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Kontogiorgi M, Exarchos D, Charitos C, Floros I, Rontogianni D, Roussos C, Routsi C: Primary right atrium angiosarcoma mimicking pericarditis. World J Surg Oncol; 2007;5:120

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Primary cardiac neoplasms occur rarely and most of them are benign.
  • Malignant tumors including angiosarcoma are extremely rare and have a non specific clinical presentation and a poor prognosis.
  • Autopsy revealed the mass of the right atrium, which was identified on histological examination as primary cardiac angiosarcoma.
  • CONCLUSION: This case highlights the difficulties both in early diagnosis and in the management of patients with cardiac angiosarcoma.

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  • (PMID = 17953738.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2174942
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91. Aktoz M, Tatli E, Ege T, Yalçin O, Büyüklü M, Aksu F, Gül C, Ozdemir C: Cardiac rhabdomyoma in an adult patient presenting with right ventricular outflow tract obstruction. Int J Cardiol; 2008 Nov 28;130(3):e105-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac rhabdomyoma in an adult patient presenting with right ventricular outflow tract obstruction.
  • We present a 24 year old woman with cardiac rhabdomyoma.
  • Cardiac rhabdomyoma is the most common benign cardiac tumor in infants, but in adults, cardiac rhabdomyoma is very rare.
  • These tumors are often spontaneously reversible because they are associated to the right or left ventricular outflow tract obstruction, tachyarrhythmias and heart failure where surgery is necessary.
  • [MeSH-major] Heart Neoplasms / diagnosis. Rhabdomyoma / diagnosis. Ventricular Outflow Obstruction / diagnosis

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  • (PMID = 17727983.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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92. Gotlieb AI: Cardiac fibromas. Semin Diagn Pathol; 2008 Feb;25(1):17-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac fibromas.
  • Cardiac fibroma is a rare benign nonencapsulated neoplasm of the heart.
  • It may grow to a large size, which results in a variety of clinical cardiac presentations, including sudden death.
  • [MeSH-major] Fibroma. Heart Neoplasms

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  • (PMID = 18350918.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
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93. Palecek T, Lindner J, Vitkova I, Linhart A: Papillary fibroelastoma arising from the left ventricular apex associated with nonspecific systemic symptoms. Echocardiography; 2008 May;25(5):526-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Primary cardiac tumors are very rare findings.
  • Papillary fibroelastomas are benign tumors comprising less than 10% of all primary cardiac neoplasms.
  • [MeSH-major] Fibroma / ultrasonography. Heart Neoplasms / ultrasonography
  • [MeSH-minor] Echocardiography. Female. Heart Ventricles / pathology. Heart Ventricles / surgery. Heart Ventricles / ultrasonography. Humans. Middle Aged

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  • (PMID = 18177380.001).
  • [ISSN] 0742-2822
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Chang YS, Chu PH, Jung SM, Lim KE, Chu JJ, Hsueh C, Lee YS: Unusual cardiac papillary fibroelastoma in the right ventricular outflow tract. Cardiovasc Pathol; 2005 Mar-Apr;14(2):104-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual cardiac papillary fibroelastoma in the right ventricular outflow tract.
  • Cardiac papillary fibroelastoma (CPF) is the second most common benign neoplasm of the heart.
  • This study describes the case of an 81-year-old man who was admitted to the hospital for severe vertigo and in whom a tumor at the right ventricular outflow tract (RVOT) was identified incidentally during echocardiography.
  • [MeSH-major] Fibroma / pathology. Heart Neoplasms / pathology. Heart Ventricles / pathology. Papillary Muscles / pathology

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  • (PMID = 15780802.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers; 0 / von Willebrand Factor
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95. Teixeira R, Lourenço C, Coelho L, Vieira H, Ramos D, Castro G, Monteiro P, Donato P, Ferreira MJ, Providência LA: Carney complex: a case report. Rev Port Cardiol; 2009 Feb;28(2):211-22
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  • Cardiac myxoma is the most common benign cardiac tumor, and 10% of cases are familial forms.
  • The authors present a review of the literature on the Carney complex, and a case report of a 68-year-old man with a cardiac mass, associated with a significant family history and a diagnosis of coronary embolism.
  • [MeSH-major] Endocrine System Diseases. Heart Neoplasms. Hyperpigmentation. Myxoma

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  • (PMID = 19438156.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Portugal
  • [Number-of-references] 37
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96. Ragland MM, Tak T: The role of echocardiography in diagnosing space-occupying lesions of the heart. Clin Med Res; 2006 Mar;4(1):22-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of echocardiography in diagnosing space-occupying lesions of the heart.
  • In contrast to primary cardiac tumors, which are less frequent and mostly benign in nature, the majority of intracardiac tumors are metastatic lesions.
  • Cardiac ultrasound has evolved enormously since its emergence in the 1950s and is presently the modality of choice for imaging space-occupying lesions of the heart; it provides high quality, real-time images that are extremely valuable in the evaluation of cardiac masses.
  • Although transthoracic echocardiography is an excellent initial diagnostic technique to evaluate and diagnose cardiac masses, transesophageal echocardiography provides superior image resolution and better visualization of cardiac masses in patients with suboptimal transthoracic echocardiography studies.
  • Computed tomography and magnetic resonance imaging are additional tools used for cardiac imaging and may provide useful information in addition to that obtained by echocardiography, especially when the images obtained by the latter are suboptimal.
  • [MeSH-major] Echocardiography / methods. Echocardiography, Transesophageal / methods. Heart Neoplasms / ultrasonography

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  • (PMID = 16595790.001).
  • [ISSN] 1539-4182
  • [Journal-full-title] Clinical medicine & research
  • [ISO-abbreviation] Clin Med Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
  • [Other-IDs] NLM/ PMC1447535
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97. Sonker U, Kloppenburg GT, Knoop EA, Seldenrijk CA, Morshuis WJ: Emergency surgery for acute mitral valve obstruction resulting from hemorrhage within a left atrial myxoma. Ann Thorac Surg; 2009 Feb;87(2):636-8
MedlinePlus Health Information. consumer health - Bleeding.

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  • Left atrial myxomas are benign, slow-growing primary cardiac tumors.
  • We describe a previously unreported case of interstitial hemorrhage in a left atrial myxoma leading to rapid expansion of the tumor with features of acute, mitral valve obstruction.
  • Transesophageal echocardiography showed a cystic area in the left atrial tumor that corresponded to an area of recent hemorrhage confirmed on surgical removal.
  • [MeSH-major] Heart Neoplasms / complications. Hemorrhage / surgery. Mitral Valve Stenosis / etiology. Mitral Valve Stenosis / surgery. Myxoma / complications
  • [MeSH-minor] Adult. Biopsy, Needle. Dyspnea / diagnosis. Dyspnea / etiology. Echocardiography, Transesophageal. Emergency Treatment. Follow-Up Studies. Heart Atria. Heart Valve Prosthesis Implantation / methods. Humans. Immunohistochemistry. Male. Risk Assessment. Severity of Illness Index. Treatment Outcome

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  • (PMID = 19161804.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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98. García Zubiri C, Yebra Yebra M, Salas Antón C, García Madero R, Manzano Espinosa L, Yebra Bango M: [Cardiac myxoma: an analysis of 30 patients]. Rev Clin Esp; 2009 Nov;209(10):478-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cardiac myxoma: an analysis of 30 patients].
  • INTRODUCTION: Myxomas are the most common type of benign heart tumors.
  • The aim of this study was to correlate the clinical forms of presentation of cardiac myxoma and complementary laboratory results with the morphological features of the tumor.
  • MATERIALS AND METHODS: We reviewed retrospectively a total of 30 cardiac myxomas seen in 2 institutions after a period of 22 years.
  • In the same period 5 cardiac sarcomas were identified.
  • In one patient the IL-6 production by peripherals blood cells before and after surgical tumor resection was evaluated.
  • The most prevalent clinical manifestations were cardiac symptoms (73,3%), constitutional symptoms (30%) and embolisms (26,7%).
  • All cases were diagnosed by transthoracic echocardiography and the most frequent location of the tumor was the left atrium.
  • Larger-diameter myxomas were observed in older patients and correlated with cardiac symptoms, radiological and electrocardiographical abnormalities.
  • There was no evidence of recurrence of the disease.
  • CONCLUSIONS: Myxomas are the most frequent tumors of the heart.
  • The most common initial manifestations were cardiac symptoms.
  • Diagnosis was achieved in all patients by transthoracic echocardiography.
  • The size and macroscopic appearance of the tumor correlated with the age of the patients and some clinical symptoms and laboratory RESULTS: Surgical excision was a safe and effective procedure. (c) 2009 Elsevier España, S.L.
  • [MeSH-major] Heart Neoplasms. Myxoma

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  • (PMID = 19889317.001).
  • [ISSN] 0014-2565
  • [Journal-full-title] Revista clínica española
  • [ISO-abbreviation] Rev Clin Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Spain
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99. Blackmon SH, Patel AR, Bruckner BA, Beyer EA, Rice DC, Vaporciyan AA, Wojciechowski Z, Correa AM, Reardon MJ: Cardiac autotransplantation for malignant or complex primary left-heart tumors. Tex Heart Inst J; 2008;35(3):296-300
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  • [Title] Cardiac autotransplantation for malignant or complex primary left-heart tumors.
  • Malignant or complex benign tumors of the left heart can present a formidable challenge for complete resection, due to anatomic inaccessibility.
  • Cardiac autotransplantation (cardiac explantation, ex-vivo tumor resection, reconstruction, and reimplantation) was introduced for complex benign primary left-heart cardiac tumors by Cooley and for malignant left-heart tumors by Reardon.
  • Herein, we update our previously reported experience.From April 1998 through July 2008, 20 patients underwent 21 cardiac autotransplantations for complex left-sided cardiac tumors that were nonresectable by traditional means.
  • Demographics, tumor histology, operative data, and mortality rates were analyzed.
  • Follow-up was complete in all patients.Of the 20 patients, 17 had malignant lesions, and 3 had benign disease.
  • Fourteen patients had previous resection of their cardiac tumors, and 1 patient had repeat autotransplantation for recurrent disease.
  • There were no operative deaths in patients undergoing autotransplantation alone (0/15), and 3 operative deaths in patients undergoing combined cardiac autotransplantation and pneumonectomy (3/6, 50%).
  • All 3 patients with benign disease survived surgery and are alive without recurrent disease.
  • Local recurrence occurred in 3/18 patients with malignant disease: 1 underwent successful repeat autotransplantation and 2 are receiving chemotherapy.
  • The mean survival for all patients with sarcoma is 22 months.Cardiac autotransplantation enables complete resection and accurate reconstruction in many primary malignant and complex benign left-heart tumors.

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  • (PMID = 18941651.001).
  • [ISSN] 0730-2347
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2565530
  • [Keywords] NOTNLM ; Heart neoplasms/mortality/surgery / heart transplantation/methods / replantation/methods / sarcoma/surgery / transplantation, autologous
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100. Kelekci S, Yazicioglu HF, Yilmaz B, Aygün M, Omeroglu RE: Cardiac rhabdomyoma with tuberous sclerosis: a case report. J Reprod Med; 2005 Jul;50(7):550-2
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  • [Title] Cardiac rhabdomyoma with tuberous sclerosis: a case report.
  • BACKGROUND: Rhabdomyomas are the most common benign cardiac neoplasms occurring in the fetus and neonate, with most of them identified within the first year of life.
  • Cardiac rhabdomyomas are frequently associated with tuberous sclerorosis.
  • CASE: A 25-year-old, pregnant woman with no remarkable personal or family history was referred to us for a suspected fetal cardiac anomaly.
  • Postnatal echocardiography confirmed the presence of cardiac rhabdomyoma, and periventricular subependymal multiple hamartomas were diagnosed by postnatal magnetic resonance imaging.
  • CONCLUSION: When fetal cardiac rhabdomyoma is diagnosed, careful evaluation of other fetal structures, including brain and renal parenchyma, should be performed to search for signs of tuberous sclerosis.
  • [MeSH-major] Fetal Diseases / ultrasonography. Heart Neoplasms / ultrasonography. Rhabdomyoma / ultrasonography. Tuberous Sclerosis / ultrasonography
  • [MeSH-minor] Adult. Female. Hamartoma / diagnosis. Hamartoma / embryology. Heart Septum. Heart Ventricles. Humans. Infant, Newborn. Magnetic Resonance Imaging. Pregnancy. Pregnancy Outcome. Ultrasonography, Prenatal

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  • (PMID = 16130856.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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