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1. Sarafoleanu C, Manea C, Enache R: [Endoscopic surgery for benign rhino-sinusal tumors]. Chirurgia (Bucur); 2009 May-Jun;104(3):303-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic surgery for benign rhino-sinusal tumors].
  • OBJECTIVES: Evaluation of the efficiency for endoscopical transnasal surgical techniques of rhino-sinusal benign tumors.
  • Maria" Bucharest, including 31 consecutive patients diagnosed with rhino-sinusal benign tumors.
  • RESULTS: We present the results achieved during the study over a group of patients with benign tumors from which 14 cases were inverted papillomas (45,16%), 7 cases of haemangiomas (22,58%), 3 cases of neurofibromas, and 3 cases of juvenile angiofibromas (each representing 9,67%), 2 cases of ossifying fibromas, and 2 cases of ameloblastomas (each representing 6,45%).
  • CONCLUSIONS: Endoscopic transnasal approach of benign rhino-sinusal tumors is a successful surgical method, with the advantage of no esthetics impairments, reduced hospitalization, and preservation of the patient's quality of life, with medium and long term results comparable with open surgery.
  • [MeSH-minor] Adolescent. Adult. Aged. Ameloblastoma / surgery. Angiofibroma / surgery. Child. Female. Fibroma, Ossifying / surgery. Follow-Up Studies. Hemangioma / surgery. Humans. Male. Middle Aged. Neurofibroma / surgery. Papilloma / surgery. Retrospective Studies. Treatment Outcome

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  • (PMID = 19601462.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Romania
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2. Jundt G, Reichart PA: [Benign odontogenic ectomesenchymal tumors]. Pathologe; 2008 May;29(3):199-204
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  • [Title] [Benign odontogenic ectomesenchymal tumors].
  • Whereas odontogenic fibromas and cementoblastomas are very rare lesions, odontogenic myxoma is the fourth common odontogenic tumor, preceded only by keratocystic odontogenic tumor, the odontomas, and ameloblastoma.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Ameloblastoma / classification. Ameloblastoma / pathology. Ameloblastoma / surgery. Cementoma / classification. Cementoma / pathology. Cementoma / surgery. Child. Child, Preschool. Dental Cementum / pathology. Diagnosis, Differential. Fibroma / classification. Fibroma / pathology. Fibroma / surgery. Humans. Mandible / pathology. Mandible / surgery. Mandibular Neoplasms / classification. Mandibular Neoplasms / pathology. Mandibular Neoplasms / surgery. Maxilla / pathology. Maxilla / surgery. Maxillary Neoplasms / pathology. Maxillary Neoplasms / surgery. Myxoma / classification. Myxoma / pathology. Myxoma / surgery. Osteolysis / classification. Osteolysis / pathology. Osteolysis / surgery. Prognosis. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 18392828.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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3. Sriram G, Shetty RP: Odontogenic tumors: a study of 250 cases in an Indian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Jun;105(6):e14-21
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  • Of these cases, 98.8% of the tumors were benign.
  • The most frequent histologic type was ameloblastoma (61.5%), followed by adenomatoid odontogenic tumor (12.4%) and myxomas (6%).
  • In India, ameloblastoma and adenomatoid odontogenic tumor are the most frequent odontogenic tumors, with distinct anatomic predilections.

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  • (PMID = 18417378.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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4. Vanoven BJ, Parker NP, Petruzzelli GJ: Peripheral ameloblastoma of the maxilla: a case report and literature review. Am J Otolaryngol; 2008 Sep-Oct;29(5):357-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral ameloblastoma of the maxilla: a case report and literature review.
  • Peripheral ameloblastoma is a rare, benign, extraosseous neoplasm of the odontogenic epithelium.
  • We report a case of peripheral ameloblastoma, detail our surgical therapy and review important elements in the pathological diagnosis and treatment of this unusual neoplasm.
  • [MeSH-major] Ameloblastoma / pathology. Ameloblastoma / surgery. Maxillary Neoplasms / pathology. Maxillary Neoplasms / surgery

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  • (PMID = 18722894.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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5. Kumamoto H, Ooya K: Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas. J Oral Pathol Med; 2005 Oct;34(9):565-72
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  • METHODS: Tissue specimens of 12 tooth germs, 41 benign ameloblastomas, and five malignant ameloblastomas were examined by reverse transcriptase polymerase chain reaction (RT-PCR) and immunohistochemistry to determine the expression of cytochrome c, apoptotic protease-activating factor-1 (APAF-1), caspase-9, and apoptosis-inducing factor (AIF).
  • Immunoreactivity for cytochrome c in tooth germs was slightly weaker than that in benign and malignant ameloblastomas.
  • [MeSH-major] Ameloblastoma / pathology. Apoptosis / physiology. Intracellular Signaling Peptides and Proteins / analysis. Mitochondria / physiology. Signal Transduction / physiology

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  • (PMID = 16138896.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / AIFM1 protein, human; 0 / APAF1 protein, human; 0 / Apoptosis Inducing Factor; 0 / Apoptotic Protease-Activating Factor 1; 0 / Flavoproteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Proteins; 9007-43-6 / Cytochromes c; EC 3.4.22.- / CASP9 protein, human; EC 3.4.22.- / Caspase 9; EC 3.4.22.- / Caspases
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6. Olgac V, Koseoglu BG, Aksakalli N: Odontogenic tumours in Istanbul: 527 cases. Br J Oral Maxillofac Surg; 2006 Oct;44(5):386-8
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  • Of these 527 tumours, 521 were benign and 6 were malignant.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Child. Child, Preschool. Female. Fibroma, Ossifying / epidemiology. Humans. Male. Middle Aged. Myxoma / epidemiology. Odontoma / epidemiology. Turkey / epidemiology

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  • (PMID = 16182417.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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7. dos Santos JN, De Souza VF, Azevêdo RA, Sarmento VA, Souza LB: "Hybrid" lesion of desmoplastic and conventional ameloblastoma: immunohistochemical aspects. Braz J Otorhinolaryngol; 2006 Sep-Oct;72(5):709-13
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  • [Title] "Hybrid" lesion of desmoplastic and conventional ameloblastoma: immunohistochemical aspects.
  • Ameloblastoma is a benign epithelial odontogenic tumor and is the most commonly encountered odontogenic tumor in the jaws.
  • "Hybrid" lesion of ameloblastoma is a tumor variant in which histologically, areas of follicular or plexiform ameloblastoma coexist with characteristic areas of ameloblastoma exhibiting pronounced stromal desmoplasia (desmoplastic ameloblastoma).
  • The purpose of this article is to present a case of "hybrid" lesion of desmoplastic ameloblastoma (AD) and conventional, and investigate extracellular matrix proteins such as tenascin, fibronectin, and type I collagen.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • [ErratumIn] Rev Bras Otorrinolaringol (Engl Ed). 2006 Nov-Dec;72(6):852
  • (PMID = 17221066.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Collagen Type I; 0 / Fibronectins; 0 / Neoplasm Proteins; 0 / Tenascin
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8. Luo HY, Li TJ: Odontogenic tumors: a study of 1309 cases in a Chinese population. Oral Oncol; 2009 Aug;45(8):706-11
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  • Of the 1309 OTs, 94.04% were benign and 5.06% were malignant.
  • The most frequent benign tumor was keratocystic odontogenic tumor (38.73%), followed by ameloblastoma (36.52%) and odontomas (6.11%).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Child. Child, Preschool. China / epidemiology. Female. Humans. Infant. Male. Mandibular Diseases / epidemiology. Maxillary Diseases / epidemiology. Middle Aged. Odontogenic Cysts / epidemiology. Odontoma / epidemiology. Prevalence. Young Adult

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  • (PMID = 19147397.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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9. Daneshbod Y, Khademi B, Moemeni B, Seif I, Daneshbod K: Preoperative washing cytology in the diagnosis of maxillary sinus lesions. Acta Cytol; 2010 Mar-Apr;54(2):148-58
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  • RESULTS: There were 47 malignant, 42 benign and 7 borderline cases.
  • Benign lesions included inflammatory conditions (17), squamous proliferations (6), soft tissue lesions (9) and odontogenic lesions (10).
  • Borderline lesions included hemangiopericytoma (4) and ameloblastoma (3).
  • Diagnostic agreement between cytology and follow-up biopsy was seen mostly in benign inflammatory and odontogenic lesions and in squamous cell carcinoma and salivary gland malignancies.
  • Clusters of sloughed epithelial cells, so called Creola bodies, may be a diagnostic pitfall in benign lesions.

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  • (PMID = 20391970.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Vera-Sempere F, Vera-Sirera B: Intraosseus plexiform schwannoma of the mandible: immunohistochemical differential diagnosis. J Craniofac Surg; 2010 Nov;21(6):1820-4
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  • Schwannomas and neurofibromas are the most common benign tumors derived from peripheral nerves, and whereas the head and neck region is the most common location for the occurrence of benign neural sheath neoplasms, origin within the oral cavity is uncommon, and occurrence centrally in the jaws is most unusual.
  • In current report, we present the first reported case of intraosseous plexiform schwannoma of the mandible, an extremely rare benign neurogenic tumor, diagnosed by optical and immunohistochemical procedures, showing the importance of differential diagnosis of these unusual intraosseous mandibular tumors.
  • [MeSH-minor] Ameloblastoma / diagnosis. Cranial Nerve Neoplasms / diagnosis. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Mandibular Diseases / diagnosis. Mandibular Nerve / pathology. Middle Aged. Odontogenic Cysts / diagnosis

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  • (PMID = 21119430.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Ruhin-Poncet B, Ghoul-Mazgar S, Hotton D, Capron F, Jaafoura MH, Goubin G, Berdal A: Msx and dlx homeogene expression in epithelial odontogenic tumors. J Histochem Cytochem; 2009 Jan;57(1):69-78
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  • In benign ameloblastomas, ISH localized Dlx3 transcripts and inconstantly detected Msx2 transcripts in epithelial cells.
  • [MeSH-minor] Adolescent. Adult. Ameloblastoma / metabolism. Bone Morphogenetic Protein 2 / biosynthesis. Bone Morphogenetic Protein 4 / biosynthesis. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. In Situ Hybridization. Male. Middle Aged. Neoplasm Recurrence, Local. Reverse Transcriptase Polymerase Chain Reaction. Young Adult

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  • (PMID = 18854600.001).
  • [ISSN] 0022-1554
  • [Journal-full-title] The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • [ISO-abbreviation] J. Histochem. Cytochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BMP2 protein, human; 0 / BMP4 protein, human; 0 / Bone Morphogenetic Protein 2; 0 / Bone Morphogenetic Protein 4; 0 / Distal-less homeobox proteins; 0 / Homeodomain Proteins; 0 / MSX1 Transcription Factor; 0 / MSX2 protein; 0 / Transcription Factors
  • [Other-IDs] NLM/ PMC2605714
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12. Siar CH, Nakano K, Ng KH, Tomida M, Nagatsuka H, Kawakami T: Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1. Eur J Med Res; 2010 Apr 8;15(4):180-4
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  • BACKGROUND: Squamous odontogenic tumor (SOT) is a rare benign odontogenic epithelial neoplasm.
  • Histopathologically, SOT can be easily misdiagnosed as an acanthomatous ameloblastoma.

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  • (PMID = 20554499.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / NOTCH1 protein, human; 0 / NOTCH3 protein, human; 0 / NOTCH4 protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptor, Notch1; 0 / Receptors, Notch; 0 / delta protein; 134324-36-0 / Serrate proteins
  • [Other-IDs] NLM/ PMC3401003
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13. Dabholkar JP, Vora K, Vaidya A, Sharma A: Benign jaw tumors. Indian J Otolaryngol Head Neck Surg; 2009 Sep;61(3):240-4
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  • [Title] Benign jaw tumors.
  • They are usually benign in nature and can affect the functions of mastication, swallowing and cause facial deformity.

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  • [Cites] Folia Med Cracov. 1998;39(1-2):35-141 [10481376.001]
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  • (PMID = 23120644.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3449977
  • [Keywords] NOTNLM ; Ameloblastoma / Dentigerous cyst / Jaw tumors / Odontomes / Osteoblastoma
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14. Black CC, Addante RR, Mohila CA: Intraosseous ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Nov;110(5):585-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraosseous ameloblastoma.
  • Ameloblastomas are benign slow-growing aggressive neoplasms with a poorly understood potential for rare metastasis.
  • [MeSH-major] Ameloblastoma / diagnosis. Jaw Neoplasms / diagnosis

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • [CommentIn] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 May;111(5):536; author reply 536-8 [21306924.001]
  • (PMID = 20580278.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Parkins GE, Armah G, Ampofo P: Tumours and tumour-like lesions of the lower face at Korle Bu Teaching Hospital, Ghana--an eight year study. World J Surg Oncol; 2007;5:48
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  • Sixty-two (36.3%) had benign odontogenic tumours and thirty-one (18.1%) had non-odontogenic tumour-like lesions.
  • Fifty-four (62%) of malignant tumours were squamous cell carcinoma; 58 (93.6%) of the benign odontogenic tumours were classified as ameloblastoma.
  • The mean age at presentation of all lesions was 40.4 years with over 50% of benign lesions in patients aged between 11 and 30 years.
  • Both malignant and benign tumours are seen in the Ghanaian population.
  • In the present study, SCC and ameloblastoma were the commonest malignant and benign odontogenic tumours seen respectively; the two representing more than 65% of all tumours.

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  • (PMID = 17484780.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1885260
  • [General-notes] NLM/ Original DateCompleted: 20070813
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16. Rauso R, Tartaro G, Gherardini G, Puglia F, Santagata M, Colella G: Recurrence of ameloblastoma in temporal area: primary treatment influences recurrence rate. J Craniofac Surg; 2010 May;21(3):887-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrence of ameloblastoma in temporal area: primary treatment influences recurrence rate.
  • Ameloblastomas are benign odontogenic tumors but are locally aggressive, most commonly occurring in the mandible and in the third to fifth decade of life.
  • Recurrence of ameloblastoma due to inadequate treatment is often described.
  • The authors describe a case of ameloblastoma recurrence in the temporal area and review the literature regarding recurrence and treatment.
  • [MeSH-major] Ameloblastoma / surgery. Mandibular Neoplasms / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 20485075.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Bologna-Molina R, Mosqueda-Taylor A, Lopez-Corella E, Almeida OP, Carrasco-Daza D, Garcia-Vazquez F, Farfan-Morales JE, Irigoyen-Camacho ME, Damián-Matsumura P: Syndecan-1 (CD138) and Ki-67 expression in different subtypes of ameloblastomas. Oral Oncol; 2008 Aug;44(8):805-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma is the most frequent odontogenic tumor and is considered a benign, but locally invasive, neoplasm with variable clinico-pathological expression.
  • The lack of correlation between reduction of the syndecan-1 and Ki-67 index may be due to the different histomorphologies of both types of ameloblastoma, and more studies are necessary to better understand the role of this protein in the biological behavior of these tumors.
  • [MeSH-major] Ameloblastoma / metabolism. Ki-67 Antigen / metabolism. Neoplasm Proteins / metabolism. Syndecan-1 / metabolism

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  • (PMID = 18207448.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / Syndecan-1
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18. Mortellaro C, Berrone M, Turatti G, Rimondini L, Brach Del Prever A, Canavese F, Pucci A, Farronato G: Odontogenic tumors in childhood: a retrospective study of 86 treated cases. Importance of a correct histopathologic diagnosis. J Craniofac Surg; 2008 Jul;19(4):1173-6
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  • The percent of diagnosed cases that were benign was 98.8%, and just one case of malign neoplasm is reported.
  • Ameloblastoma and myxoma showed the same incidence (11.6%).

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  • (PMID = 18650755.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Motamedi MH, Shafeie HA, Azizi T: Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report. Br Dent J; 2005 Jul 23;199(2):89-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The adenomatoid odontogenic tumour (AOT) has been known by a number of descriptive names (adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid ameloblastoma) since it was first reported and later recognised as a distinct odontogenic lesion unrelated to ameloblastoma.
  • Although it was considered to be a variant of ameloblastoma at one time leading surgeons to perform unduly aggressive surgery, the treatment outcome experience has borne out the benign, nonaggressive nature of this lesion.
  • The AOT is now considered to be a hamartoma with completely benign behaviour.

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  • (PMID = 16041334.001).
  • [ISSN] 0007-0610
  • [Journal-full-title] British dental journal
  • [ISO-abbreviation] Br Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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20. Buric N, Jovanovic G, Pesic Z, Krasic D, Radovanovic Z, Mihailovic D, Tijanic M: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol; 2009 Mar;38(3):178-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Schwannoma is a benign nerve tumour that originates from Schwann cells, which cover peripheral nerves.
  • Radiographically, mandibular intraosseous schwannoma is difficult to differentiate from bone tumours such as ameloblastoma, myxoma, fibrous dysplasia, neurofibroma, central giant cell lesion or periapical lesion, so it should be included in the list of possible periapical pathoses.

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  • (PMID = 19225090.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / S100 Proteins
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21. Gómez Oliveira G, García-Rozado A, Luaces Rey R: Intraosseous mandibular hemangioma. A case report and review of the literature. Med Oral Patol Oral Cir Bucal; 2008 Aug;13(8):E496-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • According to the World Health Organization, hemangiomas are benign vasoformative neoplasms of endothelial origin.
  • Differential diagnosis includes neoplasms such as ameloblastoma, cystic lesions such as residual cyst, keratocyst and fibro-osseous lesions such as fibrous dysplasia.

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  • (PMID = 18667983.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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22. Jeblaoui Y, Ben Neji N, Haddad S, Ouertatani L, Hchicha S: [Algorithm for the treatment of ameloblastoma in Tunisia]. Rev Stomatol Chir Maxillofac; 2007 Nov;108(5):419-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Algorithm for the treatment of ameloblastoma in Tunisia].
  • INTRODUCTION: Ameloblastoma is a benign but locally aggressive and infiltrative odontogenic neoplasm.
  • [MeSH-major] Ameloblastoma / surgery. Mandibular Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Oral Surgical Procedures / methods

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  • (PMID = 17572460.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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23. Zemann W, Feichtinger M, Kowatsch E, Kärcher H: Extensive ameloblastoma of the jaws: surgical management and immediate reconstruction using microvascular flaps. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Feb;103(2):190-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extensive ameloblastoma of the jaws: surgical management and immediate reconstruction using microvascular flaps.
  • OBJECTIVE: Ameloblastoma is a rare histological benign but locally aggressive tumor with a marked tendency for recurrence.
  • STUDY DESIGN: A review of 7 cases of giant ameloblastoma (2 in the maxillary and 5 in the mandibular region) is presented.
  • CONCLUSION: According to our opinion, immediate reconstruction is the treatment of choice after radical surgical excision of ameloblastoma.
  • [MeSH-major] Ameloblastoma / surgery. Jaw Neoplasms / surgery. Oral Surgical Procedures. Surgical Flaps

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  • (PMID = 17234534.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Artes-Martínez MJ, Prieto-Rodríguez M, Navarro-Hervás M, Peñas-Pardo L, Camañas-Sanz A, Vaquero de la Hermosa MC, Vera-Sempere FJ: Ameloblastoma. Diagnosis by means of FNAB. Report of two cases. Med Oral Patol Oral Cir Bucal; 2005 May-Jul;10(3):205-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma. Diagnosis by means of FNAB. Report of two cases.
  • In spite of their benign cytohistological appearance, they behave as invasive recurring tumors, with the possibility of metastasis.
  • DISCUSSION: FNAB is considered to be a rapid, bloodless and reliable method for the diagnosis of ameloblastoma.
  • The cytology of these tumors reveals components of the lesion that, in general, are sufficient for the diagnosis of ameloblastoma, especially in cases of recurrence.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • (PMID = 15876962.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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25. Bologna-Molina R, Mosqueda-Taylor A, de Almeida-Oslei P, Toral-Rizo V, Martínez-Mata G: Peripheral desmoplastic ameloblastoma: histopathological and immunohistochemical profile of a case. Med Oral Patol Oral Cir Bucal; 2010 Nov;15(6):e846-9
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  • [Title] Peripheral desmoplastic ameloblastoma: histopathological and immunohistochemical profile of a case.
  • In this study we present a rare case of peripheral desmoplastic ameloblastoma and discuss its clinical features, histopathology, and immunohistochemical profile.
  • Positive immunohistochemical stain for laminin V and type IV collagen suggests an inductive effect of the epithelium over the stroma while the low index of p53 protein and Ki-67 expression in epithelium and stromal cells, as well as CD138 uniform positive-stain in epithelial cells, support the benign biological behavior of this lesion.
  • Reports of new cases of peripheral desmoplastic ameloblastoma are necessary for a better understanding of the origin and behavior of this particular subtype of ameloblastoma.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • (PMID = 20526273.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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26. Bello IO, Alanen K, Slootweg PJ, Salo T: Alpha-smooth muscle actin within epithelial islands is predictive of ameloblastic carcinoma. Oral Oncol; 2009 Sep;45(9):760-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ameloblastoma is the most common clinically significant odontogenic tumor.
  • It is considered benign but locally invasive and associated with variable clinico-pathological behavior.
  • Ameloblastic carcinoma is a malignant tumor having features of ameloblastoma in addition to cytologic atypia with or without metastasis.
  • The aim of this study was to examine which epithelial and stromal markers are predictive of histologically diagnosed ameloblastic carcinoma and can sufficiently differentiate it from solid/multicystic ameloblastoma (SA).
  • [MeSH-major] Ameloblastoma / pathology. Carcinoma / pathology. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Neoplasm Proteins / metabolism

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  • (PMID = 19150605.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / CKAP4 protein, human; 0 / Calcium-Binding Proteins; 0 / Ki-67 Antigen; 0 / Membrane Proteins; 0 / Microfilament Proteins; 0 / Mucin-1; 0 / Neoplasm Proteins; 0 / calponin
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27. Shen LC, Chen YK, Hsue SS, Shaw SY: Expression of osteonectin/secreted protein acidic and rich in cysteine and matrix metalloproteinases in ameloblastoma. J Oral Pathol Med; 2010 Mar;39(3):242-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of osteonectin/secreted protein acidic and rich in cysteine and matrix metalloproteinases in ameloblastoma.
  • BACKGROUND: Ameloblastoma is the most common clinically-significant epithelial odontogenic tumor, and is considered a benign but locally-aggressive tumor of the craniofacial region.
  • We hypothesize that SPARC acts with MMPs for the local invasiveness of ameloblastoma.
  • The aim of this study was to examine the association of SPARC with MMP-1, MMP-2, and MMP-9 in ameloblastoma.
  • METHOD: Immunohistochemical expression of SPARC, MMP-1, MMP-2, and MMP-9 as well as co-expression of SPARC and MMP-9 were examined in a cohort of 23 cases of ameloblastoma.
  • RESULTS: SPARC, MMP-1, -2, and -9 were detected in the cytoplasm of the ameloblastic-like columnar cells and stellate-reticulum-like cells as well as in the stromal tissues of fibroblasts and endothelial cells of our cohort of ameloblastoma patients.
  • Furthermore, co-expression of SPARC and MMP-9 were found in 23 cases of ameloblastoma.
  • This may be the first study to demonstrate that the expression level of SPARC was statistically correlated with MMP-9 but not with MMP-1 or -2 in ameloblastoma.
  • CONCLUSION: Our results suggest a putative association between SPARC and MMPs (especially MMP-9) in ameloblastoma to regulate tumor invasion.
  • [MeSH-major] Ameloblastoma / pathology. Matrix Metalloproteinases, Secreted / analysis. Osteonectin / analysis

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  • (PMID = 20070483.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Osteonectin; EC 3.4.24.- / Matrix Metalloproteinases, Secreted; EC 3.4.24.24 / MMP2 protein, human; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.7 / MMP1 protein, human; EC 3.4.24.7 / Matrix Metalloproteinase 1
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28. Ram H, Mohammad S, Husain N, Gupta PN: Ameloblastic carcinoma. J Maxillofac Oral Surg; 2010 Dec;9(4):415-9
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  • It may appear de novo or originate from a pre-existing ameloblastoma or odontogenic cyst.
  • It exhibits cytological features of ameloblastoma and carcinoma.
  • It may present as a cystic lesion with benign clinical features or as a large tissue mass with ulceration, significant bone resorption and tooth mobility.

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  • (PMID = 22190836.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3177477
  • [Keywords] NOTNLM ; Ameloblastic carcinoma / Ameloblastoma / Odontogenic tumor
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29. Ladeinde AL, Ogunlewe MO, Bamgbose BO, Adeyemo WL, Ajayi OF, Arotiba GT, Akinwande JA: Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital. Quintessence Int; 2006 Jan;37(1):69-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital.
  • OBJECTIVE: The aim of the study was to review all the cases of ameloblastoma seen at the Oral and Maxillofacial Surgery Clinic of the Lagos University Teaching Hospital, Nigeria, between 1980 and 2003.
  • METHODS AND MATERIALS: In this retrospective study, case files and biopsy reports of new cases of ameloblastoma covering a 24-year period were retrieved and analyzed for sex, age on presentation, histologic type, and site distribution.
  • RESULTS: A total of 207 cases of ameloblastoma were seen in the given period.
  • One hundred and ninety-eight (95.7%) were benign, and 9 (4.3%) were malignant.
  • The average ages on presentation for ameloblastoma and ameloblastic carcinoma were 31.67 and 46.44 years, respectively.
  • The most common histologic type was follicular ameloblastoma (25.1%).
  • CONCLUSIONS: Ameloblastoma with a predilection for the posterior mandibular region is relatively common in our environment.
  • [MeSH-major] Ameloblastoma / epidemiology. Mandibular Neoplasms / epidemiology

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  • (PMID = 16429706.001).
  • [ISSN] 0033-6572
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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30. Bisinelli JC, Ioshii S, Retamoso LB, Moysés ST, Moysés SJ, Tanaka OM: Conservative treatment of unicystic ameloblastoma. Am J Orthod Dentofacial Orthop; 2010 Mar;137(3):396-400
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  • [Title] Conservative treatment of unicystic ameloblastoma.
  • INTRODUCTION: Ameloblastomas are benign asymptomatic intraosseous lesions that affect the bones of the maxillomandibular complex, interfering both in function and facial esthetic appearance.
  • METHODS AND RESULTS: The aim of this report is to relate a case of unicystic ameloblastoma with conservative treatment and with indication for orthodontic treatment.
  • CONCLUSION: The histopathologic exam of the surgical tissue provided the final diagnosis of ameloblastoma, as the lesion had not presented in its classical form and in atypical locations, as in this case involving a tooth that had not yet erupted.
  • [MeSH-major] Ameloblastoma / surgery. Mandibular Diseases / surgery

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  • [Copyright] 2010 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.
  • [CommentIn] Am J Orthod Dentofacial Orthop. 2010 Dec;138(6):684-5; discussion 685-6 [21130304.001]
  • (PMID = 20197180.001).
  • [ISSN] 1097-6752
  • [Journal-full-title] American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
  • [ISO-abbreviation] Am J Orthod Dentofacial Orthop
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Friedrich RE, Zustin J, Scheuer HA: Adenomatoid odontogenic tumour of the mandible. Anticancer Res; 2010 May;30(5):1787-92
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  • Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin.
  • Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy.

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  • (PMID = 20592380.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Actins; 68238-35-7 / Keratins
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32. Correnti M, Rossi M, Avila M, Perrone M, Rivera H: Human papillomavirus in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Sep;110(3):e20-4
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  • [Title] Human papillomavirus in ameloblastoma.
  • OBJECTIVE: Ameloblastomas are benign epithelial tumors of odontogenic origin, with a high recurrence rate and local aggressiveness.
  • [MeSH-major] Alphapapillomavirus / isolation & purification. Ameloblastoma / virology. Mandibular Neoplasms / virology. Papillomavirus Infections / diagnosis

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20727492.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
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33. Sannomiya EK, Silva JV, Brito AA, Saez DM, Angelieri F, Dalben Gda S: Surgical planning for resection of an ameloblastoma and reconstruction of the mandible using a selective laser sintering 3D biomodel. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Jul;106(1):e36-40
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  • [Title] Surgical planning for resection of an ameloblastoma and reconstruction of the mandible using a selective laser sintering 3D biomodel.
  • Ameloblastoma is a benign locally aggressive infiltrative odontogenic lesion.
  • The treatment for ameloblastoma varies from curettage to en bloc resection, and the reported recurrence rates after treatment are high; the safety margin of resection is important to avoid recurrence.
  • The development of new prototyping systems provides accurate 3D biomodels on which surgery can be simulated, especially in cases of ameloblastoma, in which the safety margin is important for treatment success.
  • A case of mandibular follicular ameloblastoma is reported where a 3D biomodel was used before and during surgery.
  • [MeSH-major] Ameloblastoma / surgery. Mandible / surgery. Mandibular Neoplasms / surgery. Models, Anatomic. Oral Surgical Procedures / methods. Surgery, Computer-Assisted

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  • (PMID = 18585610.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Kumamoto H, Ooya K: Expression of tumor necrosis factor alpha, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas. J Oral Pathol Med; 2005 May;34(5):287-94
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  • METHODS: Tissue specimens of 10 tooth germs, 40 benign ameloblastomas, and five malignant ameloblastomas were examined by reverse transcriptase-polymerase chain reaction (RT-PCR) and immunohistochemistry to determine the expression of TNFalpha, TNF receptor I (TNFRI), TRAIL, TRAIL receptor 1 (TRAIL-R1), TRAIL-R2, caspase-8, and nuclear factor-kappaB (NF-kappaB).
  • Expression of caspase-8 mRNA was identified in six of 33 ameloblastomas, but not in 10 tooth germs or one malignant ameloblastoma.
  • [MeSH-major] Ameloblastoma / metabolism. Apoptosis. Jaw Neoplasms / metabolism. Membrane Glycoproteins / biosynthesis. Tumor Necrosis Factor-alpha / biosynthesis

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  • (PMID = 15817072.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Membrane Glycoproteins; 0 / NF-kappa B; 0 / RNA, Messenger; 0 / Receptors, TNF-Related Apoptosis-Inducing Ligand; 0 / Receptors, Tumor Necrosis Factor; 0 / TNF-Related Apoptosis-Inducing Ligand; 0 / TNFRSF10A protein, human; 0 / TNFRSF10B protein, human; 0 / TNFSF10 protein, human; 0 / Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; 0 / Tumor Necrosis Factor-alpha; EC 3.4.22.- / CASP8 protein, human; EC 3.4.22.- / Caspase 8; EC 3.4.22.- / Caspases
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35. Khalifa GA, Shokier HM, Abo-Hager EA: Evaluation of neoplastic nature of keratocystic odontogenic tumor versus ameloblastoma. J Egypt Natl Canc Inst; 2010 Mar;22(1):61-72
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  • [Title] Evaluation of neoplastic nature of keratocystic odontogenic tumor versus ameloblastoma.
  • OBJECTIVE: Although most of odontogenic tumors are benign, some of them will show locally destructive behavior, as keratocystic odontogenic tumor (KCOT) is now known as a benign but aggressive odontogenic neoplasm.
  • The aim of this study is to evaluate and compare the extracellular degradation potentiality (MMP-2) and apoptosis (caspase-3) of the epithelial lining in KCOT versus radicular cysts and ameloblastoma, in order to reinforce its classification as an odontogenic tumor.
  • MATERIAL AND METHODS: Twenty-six surgical specimens including keratocyst odontogenic tumor (KCOT; n=11), ameloblastoma (AB; n=8) and radicular cysts (RC; n=7) were examined for expression of MMP-2 and caspase-3 using the immunohistochemical method.
  • KEY WORDS: Keratocystic odontogenic tumor (KCOT) - Ameloblastoma (AB) - Radicular cyst (RC) - Matrix metalloproteinase-2 (MMP-2) - Caspase-3.

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  • (PMID = 21503008.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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36. Farah-Klibi F, Ferchichi L, Beyâa Rassou H, Zairi I, Rameh S, Adouani A, Ben Jilani SB, Zermani R: [Adenomatoid odontogenic tumor: two cases]. Rev Stomatol Chir Maxillofac; 2007 Feb;108(1):61-4
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  • INTRODUCTION: Adenomatoid odontogenic tumor, initially referred to as adenoameloblastoma, is a rare and benign odontogenic tumor.
  • DISCUSSION: The clinical, radiological and histological features of adenomatoid odontogenic tumor are distinct from those of ameloblastoma.

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  • (PMID = 17275864.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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37. Abu-Id MH, Kreusch T, Brüschke C: [Glandular odontogenic cyst of the mandible. Case report]. Mund Kiefer Gesichtschir; 2005 May;9(3):188-92
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  • The biopsy taken showed a benign cyst although the clinical aspect was similar to an ameloblastoma.

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  • (PMID = 15806427.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
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38. Kpemissi E, Amana B, Tchandana K: [Mandibular tumours: epidemology, diagnostic and therapeutic aspects concerning 91 cases]. Mali Med; 2009;24(3):47-52
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  • The benign forms were the most frequent (72.88%), the ameloblastoma in particular.
  • CONCLUSION: The mandibular tumours were relatively frequent and predominated by the ameloblastoma.

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  • (PMID = 20093221.001).
  • [ISSN] 1993-0836
  • [Journal-full-title] Le Mali médical
  • [ISO-abbreviation] Mali Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mali
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39. Matijević M, Leović D, Popić B, Zubcić V, Kopić V, Prlić A, Siber S, Dinjar K: The importance of thorough preoperative diagnostics of maxillary ameloblastoma: report of three cases. Coll Antropol; 2010 Dec;34(4):1445-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The importance of thorough preoperative diagnostics of maxillary ameloblastoma: report of three cases.
  • Ameloblastoma, especially maxillary, is a rare benign neoplasm of odontogenic origin.
  • Diagnosis of significant number of lesions is usually established postoperatively, because ameloblastoma, especially the unicystic form, mimics wide range of more frequent jaw lesions.
  • From January 1993 to December 2005, three cases of the maxillary ameloblastoma were surgically treated at our Department.
  • [MeSH-major] Ameloblastoma / diagnosis. Maxillary Neoplasms / diagnosis

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  • (PMID = 21874736.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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40. Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, Akinwande JA: Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Feb;99(2):191-5
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  • Three hundred and eight (96.6%) were intraosseous, and 11 (3.4%) were peripheral (peripheral odontogenic fibroma=7; peripheral myxoma=3; peripheral ameloblastoma=1).
  • Among these cases, 96.6% of the tumors were benign and 3.4% were malignant.
  • Ameloblastoma with predilection for the mandible was the most frequent odontogenic tumor (63%), followed by adenomatoid odontogenic tumor (AOT) (7.5%), myxoma (6.5%), calcifying epithelial odontogenic cyst (5.3%), and odontogenic fibroma (5.3%).
  • The mean ages of patients with AOT, ameloblastic fibroma, and odontoma were significantly lower than those with ameloblastoma ( P<.05).
  • No significant difference was found between the mean ages of patients with benign odontogenic tumors and those with malignant odontogenic tumors ( P=.058).
  • CONCLUSIONS: Odontogenic tumors, especially ameloblastoma, are not considered rare among Nigerians, whereas odontoma, regarded as the most frequent odontogenic tumor in North and South America, is rare.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Child. Child, Preschool. Female. Hospitals, Teaching / statistics & numerical data. Humans. Jaw Neoplasms / epidemiology. Male. Mandibular Neoplasms / epidemiology. Middle Aged. Myxoma / epidemiology. Nigeria / epidemiology. Odontogenic Cyst, Calcifying / epidemiology. Odontoma / epidemiology. Retrospective Studies

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  • (PMID = 15660091.001).
  • [ISSN] 1079-2104
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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41. Jundt G, Reichart PA: [Malignant odontogenic tumors]. Pathologe; 2008 May;29(3):205-13
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  • As with benign odontogenic tumors, malignant epithelial odontogenic tumors or odontogenic carcinomas are distinguished from the even rarer mesenchymal ones, the odontogenic sarcomas.
  • Odontogenic carcinomas comprise ameloblastic carcinoma (AmCa), primary intraosseous carcinoma (PIOC), clear cell odontogenic carcinoma, odontogenic ghost cell carcinoma (OGCC), and the special case of metastasizing ameloblastoma.
  • Whereas metastasizing ameloblastoma can be diagnosed only after having metastasized, all other malignant odontogenic tumors present with atypia, increased cellularity and mitoses, and invasion.
  • [MeSH-minor] Ameloblastoma / classification. Ameloblastoma / pathology. Carcinoma / classification. Carcinoma / pathology. Carcinosarcoma / classification. Carcinosarcoma / pathology. Diagnosis, Differential. Humans. Jaw / pathology. Neoplasm Invasiveness. Sarcoma / classification. Sarcoma / pathology

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  • (PMID = 18392827.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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42. Vayvada H, Mola F, Menderes A, Yilmaz M: Surgical management of ameloblastoma in the mandible: Segmental mandibulectomy and immediate reconstruction with free fibula or deep circumflex iliac artery flap (evaluation of the long-term esthetic and functional results). J Oral Maxillofac Surg; 2006 Oct;64(10):1532-9
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  • [Title] Surgical management of ameloblastoma in the mandible: Segmental mandibulectomy and immediate reconstruction with free fibula or deep circumflex iliac artery flap (evaluation of the long-term esthetic and functional results).
  • PURPOSE: Ameloblastoma is responsible for 1% of all the oral and maxillomandibular cysts and tumors.
  • It is odontogenic in origin and benign in nature but it has a high percentage of local recurrence rate and possible malignant development when treated inadequately.
  • With the advancement of craniofacial surgical techniques, use of free flaps for mandibular reconstruction, and dental rehabilitation (such as osseointegration), the segmental mandibulectomy and immediate reconstruction with free flaps are beginning to be used more effectively for the treatment of the mandibular ameloblastoma.
  • The aim of this article is to evaluate the clinical results of the patients with mandibular ameloblastoma who were treated with segmental mandibulectomy and immediate reconstruction with free flaps.
  • PATIENTS AND METHODS: We present 11 patients who had segmental mandibulectomy and immediate reconstruction with free deep circumflex iliac artery or fibular flap for treatment of mandibular ameloblastoma.
  • CONCLUSIONS: We experienced that segmental mandibulectomy with safe borders and immediate reconstruction with free fibula flap or deep circumflex iliac artery (DCIA) flap is an ideal treatment method for mandibular ameloblastoma.
  • [MeSH-major] Ameloblastoma / surgery. Mandible / surgery. Mandibular Neoplasms / surgery. Oral Surgical Procedures. Surgical Flaps

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  • (PMID = 16982313.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Kumamoto H, Ooya K: Immunohistochemical detection of platelet-derived endothelial cell growth factor/thymidine phosphorylase and angiopoietins in ameloblastic tumors. J Oral Pathol Med; 2006 Nov;35(10):606-12
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  • Immunoreactivity for angiopoietin-1 and -2 was detected predominantly in odontogenic epithelial cells near the basement membrane in tooth germs and in benign and malignant ameloblastic tumors.
  • [MeSH-major] Ameloblastoma / chemistry. Angiopoietin-1 / analysis. Angiopoietin-2 / analysis. Jaw Neoplasms / chemistry. Thymidine Phosphorylase / analysis

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  • (PMID = 17032393.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / ANGPT1 protein, human; 0 / Angiopoietin-1; 0 / Angiopoietin-2; EC 2.4.2.4 / Thymidine Phosphorylase
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44. Powers J, Zhao Y, Lin S, McCabe ER: The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation. Dev Genes Evol; 2009 Aug;219(8):419-25
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  • [Title] The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation.
  • Based on the zebrafish observations, we demonstrated novel DAX1 expression in normal human dental, benign ameloblastoma, and malignant ameloblastoma tissues.
  • The association of NR0B1 and its protein product DAX1 with primary tooth development and ameloblastoma tumorigenesis is an association not previously described.
  • [MeSH-minor] Ameloblastoma / genetics. Animals. Embryo, Nonmammalian / metabolism. Gene Expression Regulation, Developmental. Homeodomain Proteins. Humans. Tooth / embryology

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  • [Cites] Development. 2000 Jan;127(2):217-24 [10603340.001]
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  • (PMID = 19826837.001).
  • [ISSN] 1432-041X
  • [Journal-full-title] Development genes and evolution
  • [ISO-abbreviation] Dev. Genes Evol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DAX-1 Orphan Nuclear Receptor; 0 / Homeodomain Proteins; 0 / NR0B1 protein, human; 0 / Zebrafish Proteins
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45. Brooks JK, Al-Mubarak H, Ribera MJ, Cohen PD, Ross DS, Scheper MA: Diminutive, interradicular "hybrid" desmoplastic/acanthomatous ameloblastoma. Quintessence Int; 2010 Mar;41(3):209-12
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  • [Title] Diminutive, interradicular "hybrid" desmoplastic/acanthomatous ameloblastoma.
  • Ameloblastomas are benign aggressive odontogentic tumors that exhibit insidious growth rates with attainment of extensive dimesions.
  • This article reports an atypical case of a small, painful ameloblastoma arising between the roots of the mandibular left canine and lateral incisor in a 66-year-old female.
  • Histopathology revealed a "hybrid" ameloblastoma with a pronounced desmoplastic pattern and acanthomatous changes.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • (PMID = 20213021.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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46. Yuan XP, Xie BK, Lin XF, Liang BL, Zhang F, Li JT: [Value of multi-slice spiral CT with three-dimensional reconstruction in the diagnosis of neoplastic lesions in the jawbones]. Nan Fang Yi Ke Da Xue Xue Bao; 2008 Aug;28(9):1700-2, 1706
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  • Of these patients, 14 had ameloblastoma, 8 had hemangioma, 3 had osteosarcoma, 3 had ossifying fibroma, 2 had chondrosarcoma, 2 had fibrosarcoma, and 1 had odontogenic myxoma.
  • Benign tumors were most visualized as bone expansion changes with well defined ovoid or lobulated borderlines, and malignant ones often resulted in adjacent bony destruction and soft tissue masses.
  • [MeSH-minor] Adolescent. Adult. Ameloblastoma / diagnosis. Female. Hemangioma / diagnosis. Humans. Male. Middle Aged. Reproducibility of Results. Sensitivity and Specificity. Young Adult

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  • (PMID = 18819902.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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47. Dimba EA, Gichana J, Limo AK, Wakoli KA, Chindia ML, Awange DO: An audit of oral diseases at a Nairobi centre, 2000-2004. Int Dent J; 2007 Dec;57(6):439-44
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  • Benign tumours (mean age +/- SD = 29.93 +/- 18.27 years) peaked in the third decade and tended to affect men at a younger age (p = 0.001).
  • The most common benign tumour was the ameloblastoma (50.23%: n = 109), which predominantly affected the mandible, and also occurred in male patients at a younger age (p = 0.023).
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Carcinoma, Squamous Cell / epidemiology. Child. Child, Preschool. Cysts / epidemiology. Female. Humans. Hyperplasia / epidemiology. Incidence. Infant. Infant, Newborn. Kenya / epidemiology. Male. Middle Aged. Mouth Neoplasms / epidemiology. Retrospective Studies. Sex Distribution

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  • (PMID = 18265777.001).
  • [ISSN] 0020-6539
  • [Journal-full-title] International dental journal
  • [ISO-abbreviation] Int Dent J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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48. Sharaf B, Levine JP, Hirsch DL, Bastidas JA, Schiff BA, Garfein ES: Importance of computer-aided design and manufacturing technology in the multidisciplinary approach to head and neck reconstruction. J Craniofac Surg; 2010 Jul;21(4):1277-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The free fibular flap is the standard method for reconstructing large mandibular defects after benign or malignant tumor ablation.
  • [MeSH-major] Ameloblastoma / surgery. Carcinoma, Squamous Cell / surgery. Computer-Aided Design. Head and Neck Neoplasms / surgery. Mandibular Neoplasms / surgery. Surgical Flaps

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  • (PMID = 20613609.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Tsai CY, Wei FC, Chang YL, Chen YY, Chen CT: Vastus lateralis muscle flap used for reconstruction of the maxilla after radical resection of recurrent ameloblastoma. Chang Gung Med J; 2006 May-Jun;29(3):331-5
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  • [Title] Vastus lateralis muscle flap used for reconstruction of the maxilla after radical resection of recurrent ameloblastoma.
  • Maxillary ameloblastoma is a benign odontogenic neoplasm.
  • A 23 year-old female patient presented with recurrent ameloblastoma.
  • [MeSH-major] Ameloblastoma / surgery. Maxilla / surgery. Maxillary Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Surgical Flaps

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  • (PMID = 16924896.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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50. Ide F, Mishima K, Saito I, Kusama K: Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol; 2009 Mar;3(1):18-26
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  • There were 2 cases of mistaken identity in our ameloblastoma file.
  • This tumor was found in retrospect to be consistent with an adenoid ameloblastoma with dentinoid.
  • Two cases of primary intraosseous squamous cell carcinoma appeared benign clinically and exhibited unexpected findings; an impacted third molar began to erupt in association with the growth of carcinoma and another periradicular carcinoma showed dentinoid formation.

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  • (PMID = 20596984.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2807539
  • [Keywords] NOTNLM ; Clinicopathologic correlation / Diagnostic pitfall / Epithelial odontogenic tumor / Jawbone
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51. Shirani G, Arshad M, Mohammadi F: Immediate reconstruction of a large mandibular defect of locally invasive benign lesions (a new method). J Craniofac Surg; 2007 Nov;18(6):1422-8
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  • [Title] Immediate reconstruction of a large mandibular defect of locally invasive benign lesions (a new method).
  • Locally invasive benign tumor and large lesions such as ameloblastoma, giant cell granuloma, odontogenic keratocyst, and odontogenic myxoma are a benign, invasive, lesions of the jaws that predominantly affects the mandible.
  • Despite the benign nature of these lesions, there is a high rate of local recurrence after curettage, which usually requires resection.
  • This approach represents a less invasive alternative that provides access to the mandible for curative resection of benign tumors with minimal postoperative sequelae.

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  • (PMID = 17993894.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Sharma S, Kumar D, Vashistha A, Bihani U, Trehan M: Recurrent unicystic ameloblastoma of the infratemporal and temporal fossa. Int J Clin Pediatr Dent; 2009 Jan;2(1):33-8
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  • [Title] Recurrent unicystic ameloblastoma of the infratemporal and temporal fossa.
  • The ameloblastoma has been described as benign but locally invasive; benign and locally invasive with strong tendency to recur; and locally malignant.

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  • (PMID = 25206097.001).
  • [ISSN] 0974-7052
  • [Journal-full-title] International journal of clinical pediatric dentistry
  • [ISO-abbreviation] Int J Clin Pediatr Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4086554
  • [Keywords] NOTNLM ; Unicystic / ameloblastoma / infratemporal temporal.
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53. Jing W, Xuan M, Lin Y, Wu L, Liu L, Zheng X, Tang W, Qiao J, Tian W: Odontogenic tumours: a retrospective study of 1642 cases in a Chinese population. Int J Oral Maxillofac Surg; 2007 Jan;36(1):20-5
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  • Of these tumours 1592 (97.0%) were benign and 50 (3.0%) were malignant.
  • Ameloblastoma (40.3%) was the most frequent type, followed by keratocystic odontogenic tumour (35.8%), odontoma (4.7%) and odontogenic myxoma (4.6%).
  • Ameloblastoma and keratocystic odontogenic tumours, important indications of extensive surgical procedures, are not considered rare in this Chinese population, whereas odontoma is uncommon.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Ameloblastoma / pathology. Child. Child, Preschool. China / epidemiology. Female. Humans. Male. Middle Aged. Retrospective Studies. Sex Ratio

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  • (PMID = 17156974.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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54. Mendenhall WM, Werning JW, Fernandes R, Malyapa RS, Mendenhall NP: Ameloblastoma. Am J Clin Oncol; 2007 Dec;30(6):645-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma.
  • The purpose of this article is to review the pertinent literature and discuss the optimal treatment and outcomes for patients with ameloblastoma.
  • Ameloblastoma is an uncommon benign, locally aggressive odontogenic neoplasm that usually occurs in the vicinity of the mandibular molars or ramus.
  • Uncontrolled, ameloblastoma may cause significant morbidity and occasionally death.
  • The optimal treatment for ameloblastoma is wide en bloc resection.
  • [MeSH-major] Ameloblastoma / radiotherapy. Ameloblastoma / surgery. Jaw Neoplasms / radiotherapy. Jaw Neoplasms / surgery

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  • (PMID = 18091060.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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55. Gyulai-Gaál S, Takács D, Barabás J, Tarján I, Martonffy K, Szabó G, Suba Z: [Mixed odontogenic tumors in children and adolescents]. Fogorv Sz; 2007 Apr;100(2):65-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Odontomas are calcifying benign hamartomas, and represent the most common type of odontogenic jaw tumors among patients less than 20y, having complex and compound variants.
  • [MeSH-minor] Adolescent. Ameloblastoma / diagnosis. Ameloblastoma / surgery. Child. Female. Hamartoma / diagnosis. Hamartoma / surgery. Humans. Male. Mandibular Neoplasms / diagnosis. Mandibular Neoplasms / surgery. Maxillary Neoplasms / diagnosis. Maxillary Neoplasms / surgery. Odontogenic Cysts / diagnosis. Odontogenic Cysts / surgery. Odontoma / diagnosis. Odontoma / surgery. Palatal Neoplasms / diagnosis. Palatal Neoplasms / surgery

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  • (PMID = 17546897.001).
  • [ISSN] 0015-5314
  • [Journal-full-title] Fogorvosi szemle
  • [ISO-abbreviation] Fogorv Sz
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
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56. Bello IO, Soini Y, Slootweg PJ, Salo T: Claudins 1, 4, 5, 7 and occludin in ameloblastomas and developing human teeth. J Oral Pathol Med; 2007 Jan;36(1):48-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: To analyze the distribution pattern of claudins 1, 4, 5, 7 and occludin in benign and malignant ameloblastomas and developing human teeth.
  • METHODS: Paraffin-embedded tissue specimens of 25 benign and four malignant ameloblastomas and two developing human teeth were examined immunohistochemically using antibodies against claudins 1, 4, 5, 7 and occludin.
  • There were no evident differences in the expression of claudins or occludin neither between different histologic subtypes of ameloblastomas nor between benign or malignant cases.
  • CONCLUSION: There were no clear differences in the expression levels between benign and malignant ameloblastic tumors.
  • [MeSH-major] Ameloblastoma / pathology. Membrane Proteins / analysis. Odontogenesis / physiology. Tight Junctions / pathology. Tooth Germ / pathology

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  • (PMID = 17181742.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CLDN1 protein, human; 0 / CLDN4 protein, human; 0 / CLDN5 protein, human; 0 / CLDN7 protein, human; 0 / Claudin-1; 0 / Claudin-4; 0 / Claudin-5; 0 / Claudins; 0 / Membrane Proteins; 0 / OCLN protein, human; 0 / Occludin
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57. Kumamoto H, Ohki K, Ooya K: Expression of p63 and p73 in ameloblastomas. J Oral Pathol Med; 2005 Apr;34(4):220-6
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  • METHODS: Tissue specimens of nine tooth germs and 48 benign and five malignant ameloblastomas were examined by immunohistochemistry and reverse transcriptase-polymerase chain reaction (RT-PCR) for the expression of p63 and p73.
  • TAp63 mRNA was expressed in five of eight tooth germs, 16 of 34 ameloblastomas, and one of one malignant ameloblastoma, whereas Delta Np73 mRNA was recognized in one of eight tooth germs, nine of 34 ameloblastomas, and one of one malignant ameloblastoma.
  • [MeSH-major] Ameloblastoma / genetics. Apoptosis / genetics. DNA-Binding Proteins / genetics. Genes, Tumor Suppressor. Nuclear Proteins / genetics. Phosphoproteins / genetics. Trans-Activators / genetics. Tumor Suppressor Proteins / genetics

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  • (PMID = 15752257.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; 0 / Phosphoproteins; 0 / Protein Isoforms; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; 0 / tumor suppressor protein p73
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58. Li JS, Chen WL, Huang ZQ, Zhang DM: Pediatric mandibular reconstruction after benign tumor ablation using a vascularized fibular flap. J Craniofac Surg; 2009 Mar;20(2):431-4
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  • [Title] Pediatric mandibular reconstruction after benign tumor ablation using a vascularized fibular flap.
  • Six pediatric patients ranging in age from 12 to 15 years underwent mandibular reconstruction using a vascularized fibula flap with a skin paddle, after benign tumor ablation.
  • A vascularized fibular flap is a very reliable method for reconstructing the pediatric mandible after benign tumor ablation.
  • [MeSH-minor] Adolescent. Ameloblastoma / rehabilitation. Ameloblastoma / surgery. Child. Dentures. Diet. Esthetics. Female. Fibroma, Ossifying / rehabilitation. Fibroma, Ossifying / surgery. Fibrous Dysplasia of Bone / rehabilitation. Fibrous Dysplasia of Bone / surgery. Fibula. Follow-Up Studies. Graft Survival. Humans. Male. Mandibular Diseases / rehabilitation. Mandibular Diseases / surgery. Radiography, Panoramic. Speech Intelligibility / physiology. Tissue and Organ Harvesting. Treatment Outcome. Wound Healing / physiology

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  • (PMID = 19218857.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. LeCorn DW, Bhattacharyya I, Vertucci FJ: Peripheral ameloblastoma: a case report and review of the literature. J Endod; 2006 Feb;32(2):152-4
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  • [Title] Peripheral ameloblastoma: a case report and review of the literature.
  • Peripheral ameloblastoma is a rare, benign odontogenic tumor that histologically resembles an intraosseous ameloblastoma but develops in the soft tissues of the gingiva and mucosa and exhibits an innocuous clinical behavior.
  • We report a case of a recurrent peripheral ameloblastoma in a 61-year-old man that presented as a painless swelling on the maxillary anterior labial attached gingiva.
  • The peripheral ameloblastoma should be included in the differential diagnosis of a gingival lesion clinically resembling any of the myriads of entities seen on the gingiva including a pyogenic granuloma, peripheral giant cell granuloma, or parulis/gumboil.
  • [MeSH-major] Ameloblastoma / pathology. Gingival Neoplasms / pathology

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  • (PMID = 16427467.001).
  • [ISSN] 0099-2399
  • [Journal-full-title] Journal of endodontics
  • [ISO-abbreviation] J Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 11
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60. Fiaschetti V, Fanucci E, Rascioni M, Ottria L, Barlattani A, Simonetti G: Jaw expansive lesions: population incidence and CT dentalscan role. Oral Implantol (Rome); 2010 Jul;3(3):2-10
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  • THE TECHNIQUE SENSITIVITY WAS ASSESSED FOR TWO IMPORTANT CLASSES: benign and malignant lesions.
  • 656 patients (93.1 %) out of 704 examined for a suspicious lesion on the orthopantomography had a benign lesion: (127 follicular cysts (18.2 %), 181 radicular cysts (25.1%), 93 non odontogenic cysts (13.2%), 29 fibroma (4.2%), 198 odontomes (28.2%), 24 ameloblastoma (3.6%), 4 brown tumors (0.7%), 47 (6.9%) had malignant lesions: (12 carcinoma (1.7%), 29 metastasis (4.3%), 6 sarcoma (0.8%), 1 Dentascan CT resulted to be negative (1 false positive of digital OPT).
  • The sensitivity of the technique for both groups was 99% for benign lesions and 98% for malign lesions.

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  • (PMID = 23285385.001).
  • [ISSN] 1974-5648
  • [Journal-full-title] ORAL & implantology
  • [ISO-abbreviation] Oral Implantol (Rome)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3399186
  • [Keywords] NOTNLM ; dentalscan / expansive lesions
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61. Bayi el H, El Harti K, Chbicheb S, El Wady W, Oujilal A, Kzadri M: [Odontogenic myxoma of the maxillary]. Rev Stomatol Chir Maxillofac; 2006 Nov;107(5):389-92
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  • INTRODUCTION: Odontogenic myxoma is a rare benign tumor that arises from the mesenchymal portion of the tooth germ.
  • It has a va-riable non-specific clinical and radiological appearance, and may be confused with other lesions such as ameloblastoma.

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  • (PMID = 17128194.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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62. Tincani AJ, Del Negro A, Araújo PP, Akashi HK, Neves Fda S, Martins AS: Head and neck reconstruction using infrahyoid myocutaneous flaps. Sao Paulo Med J; 2006 Sep 7;124(5):271-4
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  • Here we describe our experience with infrahyoid flaps (IHFs) employed to cover surgical defects in the oral cavity and oropharynx in patients with benign and malignant tumors.
  • Thirteen patients (92.8%) had squamous cell carcinoma (SCC) and one (7.2%) ameloblastoma.


63. Smullin SE, Faquin W, Susarla SM, Kaban LB: Peripheral desmoplastic ameloblastoma: report of a case and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Jan;105(1):37-40
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  • [Title] Peripheral desmoplastic ameloblastoma: report of a case and literature review.
  • The desmoplastic variant of ameloblastoma is a rare, locally invasive, benign tumor of the jaws, typically found in the anterior regions of the maxilla and mandible.
  • This ameloblastoma variant has been described as an intraosseous tumor; to our knowledge, there have been no published cases of a peripheral desmoplastic ameloblastoma.
  • The purpose of this case report is to describe a patient with a desmoplastic ameloblastoma localized to the soft tissue of the palate with no osseous involvement.
  • [MeSH-major] Ameloblastoma / pathology. Palatal Neoplasms / pathology

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  • (PMID = 17764981.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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64. Gyulai-Gaál S, Takács D, Szabó G, Suba Z: Mixed odontogenic tumors in children and adolescents. J Craniofac Surg; 2007 Nov;18(6):1338-42
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  • Odontomas are calcifying benign hamartomas and represent the most common type of odontogenic jaw tumors among patients less than 20 years old.
  • [MeSH-minor] Adolescent. Ameloblastoma / complications. Ameloblastoma / pathology. Child. Female. Fibroma / complications. Fibroma / pathology. Humans. Male. Odontoma / complications. Odontoma / pathology. Tooth Eruption, Ectopic / etiology. Tooth, Impacted / etiology. Tooth, Unerupted / etiology

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  • (PMID = 17993878.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Zhang B, Zhang J, Xu ZY, Xie HL: Expression of RECK and matrix metalloproteinase-2 in ameloblastoma. BMC Cancer; 2009;9:427
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  • [Title] Expression of RECK and matrix metalloproteinase-2 in ameloblastoma.
  • BACKGROUND: Ameloblastoma is a frequent odontogenic benign tumor characterized by local invasiveness, high risk of recurrence and occasional metastasis and malignant transformation.
  • The aim of this study was to characterize the relationship between RECK and MMP-2 expression and the clinical manifestation of ameloblastoma.
  • METHODS: Immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR) were employed to detect the protein and mRNA expression of RECK and MMP-2 in keratocystic odontogenic tumor (KCOT), ameloblastoma and ameloblastic carcinoma.
  • RESULTS: RECK protein expression was significantly reduced in KCOT (87.5%), ameloblastoma (56.5%) and ameloblastic carcinoma (0%) (P < 0.01), and was significantly lower in recurrent ameloblastoma compared with primary ameloblastoma (P < 0.01), but did not differ by histological type of ameloblastoma.
  • MMP-2 protein expression was significantly higher in ameloblastoma and ameloblastic carcinoma compared with KCOT (P < 0.01).
  • RECK mRNA expression was significantly lower in ameloblastoma than in KCOT (P < 0.01), lower in recurrent ameloblastoma than in primary ameloblastoma, and was negative in ameloblastic carcinoma.
  • MMP-2 mRNA expression was significantly higher in ameloblastoma compared with KCOT (P < 0.01), but was no different in recurrent ameloblastoma versus primary ameloblastoma.
  • RECK protein expression was negatively associated with MMP-2 protein expression in ameloblastoma (r = -0.431, P < 0.01).
  • CONCLUSION: Low or no RECK expression and increased MMP-2 expression may be associated with negative clinical findings in ameloblastoma.
  • RECK may participate in the invasion, recurrence and malignant transformation of ameloblastoma by regulating MMP-2 at the post-transcriptional level.
  • [MeSH-major] Ameloblastoma / metabolism. Jaw Neoplasms / metabolism. Matrix Metalloproteinase 2 / biosynthesis. Membrane Glycoproteins / biosynthesis

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  • [Cites] Cell. 2001 Dec 14;107(6):789-800 [11747814.001]
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  • (PMID = 19995435.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / RECK protein, human; 0 / RNA, Messenger; EC 3.4.24.24 / Matrix Metalloproteinase 2
  • [Other-IDs] NLM/ PMC2794878
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66. Abiko Y, Nagayasu H, Takeshima M, Yamazaki M, Nishimura M, Kusano K, Kitajo H, Saitoh M, Kawakami T, Chiba I, Kaku T: Ameloblastic carcinoma ex ameloblastoma: report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jan;103(1):72-6
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  • [Title] Ameloblastic carcinoma ex ameloblastoma: report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation.
  • Ameloblastic carcinoma meeting the WHO criteria may arise either as a result of malignant change in a pre-existing benign ameloblastoma (carcinoma ex ameloblastoma) or as a primary malignant ameloblastoma not preceded by an ordinary ameloblastoma (de novo carcinoma).
  • We report a case of ameloblastic carcinoma ex ameloblastoma and examine how this case underwent malignant transformation.
  • The DNA was extracted separately from benign and malignant areas in paraffin sections of the tumor.
  • The results indicate that hypermethylation of p16 may have been involved in the malignant transformation of the ameloblastoma in the present case.
  • [MeSH-major] Ameloblastoma / genetics. Cell Transformation, Neoplastic / genetics. CpG Islands / genetics. DNA Methylation. Genes, p16. Mandibular Neoplasms / genetics

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  • (PMID = 17178497.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cadherins; 0 / DNA, Neoplasm; 0 / DNA-Binding Proteins; 0 / PDRG1 protein, human
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67. Tyndorf MM, Manowska B, Arkuszewski P: [Usefulness of classic radiographs in the preliminary evaluation of mandibular radiolucencies]. Wiad Lek; 2008;61(10-12):258-62
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  • Usually they are benign lesions such as odontogenic cyst or periapical granulomas but very similar radiological morphology may deal with aggressive tumors such as ameloblastoma, myxoma or calcifying epidermoid odontogenic tumor (CEOT).
  • MATERIAL AND METHOD: 127 radiographs were considered and evaluated accord to Lodwick classification as benign lesions.
  • CEOT, ameloblastoma or fibroma osyficans. CONCLUSIONS:.

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  • (PMID = 19323065.001).
  • [ISSN] 0043-5147
  • [Journal-full-title] Wiadomości lekarskie (Warsaw, Poland : 1960)
  • [ISO-abbreviation] Wiad. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Poland
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68. Torres-Lagares D, Infante-Cossío P, Hernández-Guisado JM, Gutiérrez-Pérez JL: Mandibular ameloblastoma. A review of the literature and presentation of six cases. Med Oral Patol Oral Cir Bucal; 2005 May-Jul;10(3):231-8
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  • [Title] Mandibular ameloblastoma. A review of the literature and presentation of six cases.
  • Ameloblastoma is a benign odontogenic tumour of epithelial origin without induction in the connective tissue.
  • Articles have recently been published with the purpose of providing updated knowledge and therapeutic approaches to ameloblastoma.
  • We present six cases of patients with localised mandibular ameloblastoma who were treated during the last seven years.
  • We present data on clinical appearance, histological characteristics, and therapeutic approach that was used, which included excision of the lesion, perilesional drilling of the bone, or block resection, according to the type of ameloblastoma.
  • The aim of this paper is to review the concepts relating to ameloblastoma that have been published recently and to assess their influence on the clinical attitude taken when facing this pathology, using our experience with ameloblastoma as a starting point to illustrate this discussion.
  • [MeSH-major] Ameloblastoma / pathology. Mandibular Neoplasms / pathology

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  • (PMID = 15876966.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 33
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69. Zhang B, Zhang J, Huang HZ, Chen WL, Tao Q, Zeng DL, Zhang LT, Xu JH: Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity. J Oral Pathol Med; 2009 Oct;38(9):731-6
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  • [Title] Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity.
  • BACKGROUND: Ameloblastoma is an odontogenic benign tumor characterized by local invasiveness and most of its local recurrences clinically result from local invasion.
  • This study used matrix metalloproteinase-2 (MMP-2) inhibitor I (MMP-2I) to investigate the role played by MMP-2 activity in the local invasiveness of ameloblastoma.
  • METHODS: The cells and xenografts of ameloblastoma were treated with MMP-2I and treatment group were compared with the control group.
  • In vivo, bilateral subrenal capsule xenograft transplantation of ameloblastoma was performed in 10 nude mice and the invasion of ameloblastoma into the renal parenchyma was observed.
  • CONCLUSIONS: Inhibitor of MMP-2 activity suppressed the local invasive capability of ameloblastoma by decreasing MMP-2 activity.
  • MMP-2 activity is in relation with invasive capacity of ameloblastoma.
  • [MeSH-major] Ameloblastoma / enzymology. Jaw Neoplasms / enzymology. Matrix Metalloproteinase Inhibitors. Tissue Inhibitor of Metalloproteinase-2 / pharmacology

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  • (PMID = 19473446.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Matrix Metalloproteinase Inhibitors; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; EC 3.4.24.24 / Matrix Metalloproteinase 2
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70. Łapienis M, Kaczmarczyk D, Zimmer-Nowicka J, Niedźwiecka I, Jesionek-Kupnicka D, Morawiec-Bajda A: [Ameloblastoma of the maxillary sinus--a case report]. Otolaryngol Pol; 2008;62(6):784-6
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  • [Title] [Ameloblastoma of the maxillary sinus--a case report].
  • Ameloblastoma (adamantinoma) is a benign neoplasm deriving from the enamel organ.
  • About 20% of described cases of ameloblastoma relate to the jaw, its very rare location is gingiva or cheak tunica mucosa.
  • The essay presents a case of ameloblastoma of a maxillary sinus in a 65-year-old man.
  • The diagnostic and treatment algorithm in ameloblastoma is discussed.
  • [MeSH-major] Ameloblastoma / pathology. Ameloblastoma / surgery. Maxillary Sinus Neoplasms / pathology. Maxillary Sinus Neoplasms / surgery

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  • (PMID = 19205533.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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71. Chen WL, Ye JT, Yang ZH, Huang ZQ, Zhang DM, Wang K: Reverse facial artery-submental artery mandibular osteomuscular flap for the reconstruction of maxillary defects following the removal of benign tumors. Head Neck; 2009 Jun;31(6):725-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reverse facial artery-submental artery mandibular osteomuscular flap for the reconstruction of maxillary defects following the removal of benign tumors.
  • METHODS: Eight maxillary defects following benign tumor ablation were repaired with reverse facial artery-submental artery mandibular osteomuscular flaps.
  • Maxillary odontogenic myxoma was present in 3 cases, maxillary fibrous dysplasia and ameloblastoma in 2 cases each, and chondromyxoid fibroma in 1 case.

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  • [Copyright] (c) 2009 Wiley Periodicals, Inc.
  • (PMID = 19260126.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Kumamoto H, Ooya K: Immunohistochemical detection of MT1-MMP, RECK, and EMMPRIN in ameloblastic tumors. J Oral Pathol Med; 2006 Jul;35(6):345-51
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  • RESULTS: Immunohistochemical reactivity for MT1-MMP, RECK and EMMPRIN was detected predominantly in odontogenic epithelial cells near the basement membrane in tooth germs and benign and malignant ameloblastic tumors.
  • The level of immunoreactivity for MT1-MMP was slightly higher in benign and malignant ameloblastic tumors than in tooth germs.
  • [MeSH-major] Ameloblastoma / chemistry. Antigens, CD147 / analysis. Jaw Neoplasms / chemistry. Matrix Metalloproteinases / analysis. Membrane Glycoproteins / analysis. Tooth Germ / chemistry

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  • (PMID = 16762015.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / RECK protein, human; 136894-56-9 / Antigens, CD147; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.- / Matrix Metalloproteinases, Membrane-Associated
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73. Senra GS, Pereira AC, Murilo dos Santos L, Carvalho YR, Brandão AA: Malignant ameloblastoma metastasis to the lung: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Feb;105(2):e42-6
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  • [Title] Malignant ameloblastoma metastasis to the lung: a case report.
  • Ameloblastoma is an odontogenic tumor, usually benign, which rarely metastasizes to distant organs.
  • The case of a 27-year-old white woman is described, who presented a metastatic pulmonary ameloblastoma 7 years after the removal of a mandibular ameloblastoma.
  • Clinical and CT investigation confirmed no ameloblastoma recurrence in the jaw and no other primary tumor.
  • The diagnosis of metastatic ameloblastoma was confirmed by microscopic evaluation of the pulmonary nodule.
  • [MeSH-major] Ameloblastoma / secondary. Lung Neoplasms / secondary. Mandibular Neoplasms / pathology

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  • (PMID = 18230377.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. DeVilliers P, Liu H, Suggs C, Simmons D, Daly B, Zhang S, Raubenheimer E, Larsson A, Wright T: Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol; 2008 Feb;32(2):256-60
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  • [Title] Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor.
  • Ameloblastoma is a benign, locally aggressive epithelial odontogenic tumor that has the potential to become malignant and produce metastasis to distant sites such as lungs and kidneys.
  • The expression of calretinin [calbindin2 (CALB2)] was investigated on both ameloblastoma and KCOT.
  • Nineteen cases of ameloblastoma and 17 cases of KCOT were stained with calretinin antiserum 18-0211 (Zymed, San Francisco, CA).
  • All cases (100%) of ameloblastoma showed positive calretinin staining, restricted to the neoplastic epithelial component and none (0%) of the 17 KCOTs showed positive calretinin staining.
  • Taken together, the results of this study strongly support calretinin as a useful immunohistochemical marker for ameloblastoma and malignant ameloblastoma and it can also be used in the differential diagnosis of KCOT.
  • [MeSH-major] Ameloblastoma / diagnosis. Biomarkers, Tumor / metabolism. Jaw Neoplasms / diagnosis. Odontogenic Cysts / diagnosis. Odontogenic Tumors / diagnosis. S100 Calcium Binding Protein G / metabolism

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  • (PMID = 18223328.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / DE016079
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / S100 Calcium Binding Protein G
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75. Wysluch A, Hölzle F, Maurer P: [Giant ameloblastoma of the jaw]. HNO; 2009 Nov;57(11):1193-6
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  • [Title] [Giant ameloblastoma of the jaw].
  • Ameloblastomas represent benign, epithelial alveolar tumors, which originate from epithelial enamel cells (ameloblasts).
  • As demonstrated by the case of a 71-year-old patient with giant ameloblastoma of the upper jaw, early resection is recommended.
  • [MeSH-major] Ameloblastoma / diagnosis. Mandibular Neoplasms / diagnosis

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  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Dec;104(6):e17-24 [17942338.001]
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  • (PMID = 19727626.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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76. Al-Shaham AA, Samher AA: Cemento-ossifying fibroma of the maxilla. J Plast Surg Hand Surg; 2010 Dec;44(6):318-21
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  • In 1992 The World Health Organization adopted a new classification that included these fibromas as benign osseous tumours.
  • The differential diagnosis included fibrous dysplasia, osteoid osteoma, osteoblastoma, chronic sclerosing osteomyelitis, ameloblastoma, squamous cell carcinoma of the maxillary sinus, calcifying epithelial odontogenic tumour (Pindborg tumour) and calcifying odontogenic cyst (Gorlin cyst).

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  • (PMID = 21446812.001).
  • [ISSN] 2000-6764
  • [Journal-full-title] Journal of plastic surgery and hand surgery
  • [ISO-abbreviation] J Plast Surg Hand Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
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77. Coulibaly B, Le Hémon A, Sorbier C, George L, Blanc JL, Fernandez C: [Ameloblastic carcinoma: primary or secondary?]. Ann Pathol; 2009 Feb;29(1):28-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It can arise de novo or in a preexisting benign ameloblastoma.
  • The second case concerns a woman with an ameloblastic carcinoma secondary-type developed on a preexisting follicular ameloblastoma of the mandible.
  • [MeSH-major] Ameloblastoma / pathology. Combined Modality Therapy. Odontogenic Tumors / pathology

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  • (PMID = 19233091.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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78. Kumamoto H, Ooya K: Immunohistochemical detection of retinoblastoma protein and E2 promoter-binding factor-1 in ameloblastomas. J Oral Pathol Med; 2006 Mar;35(3):183-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Tissue specimens of 10 tooth germs, 40 benign ameloblastomas, and five malignant ameloblastomas were examined immunohistochemically with the use of antibodies against RB, E2F-1, and phosphorylated RB.
  • RESULTS: Immunohistochemical reactivity for RB, E2F-1, phosphorylated RB, and Ki-67 was detected in the nuclei of odontogenic epithelial cells near the basement membrane in tooth germs and benign and malignant ameloblastomas.
  • The levels of immunoreactivity for RB, E2F-1, phosphorylated RB, and Ki-67 were slightly higher in benign and malignant ameloblastomas than in tooth germs.
  • [MeSH-major] Ameloblastoma / chemistry. E2F1 Transcription Factor / analysis. Retinoblastoma Protein / analysis

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  • (PMID = 16454815.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / E2F1 Transcription Factor; 0 / Ki-67 Antigen; 0 / Retinoblastoma Protein
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79. López-Jornet P, Bermejo-Fenoll A: Peripheral ameloblastoma of the gingiva: the importance of diagnosis. J Clin Periodontol; 2005 Jan;32(1):12-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral ameloblastoma of the gingiva: the importance of diagnosis.
  • BACKGROUND: Peripheral ameloblastoma is an extremely rare epithelial odontogenic tumor, limited to the soft tissues of the gums or oral mucosa.
  • Although the lesion is benign, it may be locally aggressive.
  • The diagnosis was peripheral ameloblastoma.
  • Consequently, peripheral ameloblastoma should not be viewed as a harmless mass.
  • [MeSH-major] Ameloblastoma / pathology. Gingival Diseases / pathology

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  • [Copyright] Copyright Blackwell Munksgaard, 2004.
  • (PMID = 15642052.001).
  • [ISSN] 0303-6979
  • [Journal-full-title] Journal of clinical periodontology
  • [ISO-abbreviation] J. Clin. Periodontol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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80. Capote-Moreno A, Acero J, García-Recuero I, Ruiz J, Serrano R, de Paz V: Giant aneurysmal bone cyst of the mandible with unusual presentation. Med Oral Patol Oral Cir Bucal; 2009 Mar;14(3):E137-40
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  • Aneurysmal bone cysts are rare benign lesions of bone tissue, infrequent in craneofacial skeleton with regard to other structures like long bones or the spine.
  • Aneurysmal bone cysts are non-neoplastic but locally aggressive tumours with occasional rapid growth that may be differentiated from other multilocular process like ameloblastoma, ossifying fibroma, epithelial cyst, giant cell granuloma and sarcomas.

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  • (PMID = 19242394.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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81. Abada RL, Kadiri F, Tawfik N, Benchakroun N, Bouchbika Z, Chekkoury AI, Benchakroun Y, Benider A: [Multiple metastases of a mandibular ameloblastoma]. Rev Stomatol Chir Maxillofac; 2005 Jun;106(3):177-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multiple metastases of a mandibular ameloblastoma].
  • INTRODUCTION: Ameloblastoma is a benign odontogenic tumor which can be locally aggressive and invasive.
  • [MeSH-major] Ameloblastoma / secondary. Mandibular Neoplasms / pathology

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  • (PMID = 15976707.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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82. Tawfik MA, Zyada MM: Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Feb;109(2):e67-73
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  • Of these, (96.3%) were benign and (3.7%) were malignant.
  • Ameloblastoma (41.5%) was the most frequent type, followed by keratocystic odontogenic tumor (19.5%), odontoma (13.4%), and odontogenic myxoma (8.5%).
  • In Dakahlia, Egypt, ameloblastoma and keratocystic odontogenic tumor are the most frequent odontogenic tumors, with distinct anatomic predilections.

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 19969486.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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83. Faitaroni LA, Bueno MR, De Carvalhosa AA, Bruehmueller Ale KA, Estrela C: Ameloblastoma suggesting large apical periodontitis. J Endod; 2008 Feb;34(2):216-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma suggesting large apical periodontitis.
  • The microscopic examination indicated a diagnosis of ameloblastoma.
  • Ameloblastoma is a benign epithelial neoplasm of odontogenic origin, and depending on the stage of development, it can mimic a periapical lesion and therefore should be considered in establishing an endodontic differential diagnosis.
  • [MeSH-major] Ameloblastoma / diagnosis. Mandibular Neoplasms / diagnosis. Periapical Periodontitis / diagnosis

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  • (PMID = 18215686.001).
  • [ISSN] 0099-2399
  • [Journal-full-title] Journal of endodontics
  • [ISO-abbreviation] J Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Kim K, Velez I, Kaltman SI, Lopez E, Stern D: Odontogenic carcinoma differentiation into rhabdomyosarcoma: report of a rare case. Quintessence Int; 2009 Nov-Dec;40(10):837-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Within the English-language literature, only 2 cases are reported of an odontogenic tumor with muscle differentiation: a benign odontogenic tumor (ameloblastoma) with differentiation into a rhabdomyosarcoma and an odontogenic sarcoma with smooth-muscle differentiation.

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  • (PMID = 19898715.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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85. Lin C, Li J, Lu N: [Analysis of 2161 cases of neoplasm in oral maxillofacial region in Xinjiang]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2010 Sep;45(9):553-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A total of 2161 patients with benign or malignant oral-maxillofacial tumors diagnosed in Department of Dentofacial Surgery of the First Affiliated Hospital of Xinjiang Medical College from 1995 to 2009 were analyzed retrospectively.
  • RESULTS: Of the 2161 cases, 58.49% (1264/2161) was benign tumors, 33.13% (716/2161) malignant tumors, and 8.38% (181/2161) tumor-like lesions.
  • The most common benign tumors were pleomorphic adenoma, hemangioma, papilloma, adenolymphoma and ameloblastoma.
  • The most common odontogenic tumors was ameloblastoma.
  • CONCLUSIONS: The common pathological type of oral and maxillofacial benign neoplasm and the most common sites of malignancy in Xinjiang region were similar to those of other places inside and outside the country.
  • [MeSH-minor] Adenolymphoma. Adenoma, Pleomorphic. Ameloblastoma. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. China / epidemiology. Face. Humans. Incidence. Mouth Mucosa. Odontogenic Tumors. Retrospective Studies. Salivary Gland Neoplasms

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  • (PMID = 21122451.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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86. Karakida K, Aoki T, Sakamoto H, Takahashi M, Akamatsu T, Ogura G, Sekido Y, Ota Y: Ameloblastic carcinoma, secondary type: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Dec;110(6):e33-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Malignant variants of ameloblastoma include metastasizing ameloblastoma, which microscopically appears benign but has metastasized and ameloblastic carcinoma that exhibits malignant histopathologic features.
  • Ameloblastic carcinoma is classified into 2 types: a primary odontogenic malignancy and a secondary type resulting from malignant transformation of ameloblastoma.
  • Therefore it is rare to find an untreated secondary type presenting with histologic features of malignant transformation from an earlier benign lesion.
  • We experienced a rare case of ameloblastic carcinoma, secondary type which might arise in an untreated ameloblastoma.
  • The mechanism by which a preexisting benign ameloblastoma goes through a malignant transformation is also described.
  • [MeSH-major] Ameloblastoma / pathology. Cell Transformation, Neoplastic / pathology. Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • [Copyright] Crown Copyright © 2010. Published by Mosby, Inc. All rights reserved.
  • (PMID = 21112523.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53
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87. Singh T, Sealey CM: Ameloblastoma: report on two cases and review of the literature. N Z Dent J; 2009 Mar;105(1):13-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma: report on two cases and review of the literature.
  • The ameloblastoma is a benign odontogenic tumour that is locally aggressive and tends to recur following treatment.
  • We present 2 cases of mandibular ameloblastoma and review the recent literature.
  • [MeSH-major] Ameloblastoma / diagnosis. Mandibular Neoplasms / diagnosis

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  • (PMID = 19418678.001).
  • [ISSN] 0028-8047
  • [Journal-full-title] The New Zealand dental journal
  • [ISO-abbreviation] N Z Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] New Zealand
  • [Number-of-references] 16
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88. Adebayo ET, Ajike SO, Adekeye EO: A review of 318 odontogenic tumors in Kaduna, Nigeria. J Oral Maxillofac Surg; 2005 Jun;63(6):811-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Twelve histopathologic types of odontogenic tumors were found with more benign (n=314; 99%) than malignant (n=4; 1%).
  • Ameloblastoma made up 233 (73%) of the tumors, followed by odontogenic myxoma (n=38; 12%), ameloblastic fibroma (n=9; 3%), and the adenomatoid odontogenic tumor (2%).
  • Three cases of calcifying odontogenic cyst were co-existent with ameloblastoma (2) and ameloblastic fibro-odontoma (1).
  • At least 8 cases of ameloblastoma (13%) recurred out of 60 followed up.
  • CONCLUSION: Ameloblastoma is a fairly common tumor of Nigerian Africans accounting for 73% of odontogenic tumors and 24% of all tumors and tumor-like lesions of the oral and perioral structures.
  • A minimum of 5 years of follow-up reviews are necessary after treatment of ameloblastoma.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Ameloblastoma / epidemiology. Ameloblastoma / pathology. Child. Female. Fibroma / epidemiology. Fibroma / pathology. Humans. Incidence. Male. Middle Aged. Neoplasm Recurrence, Local. Nigeria / epidemiology. Odontogenic Cyst, Calcifying / epidemiology. Odontogenic Cyst, Calcifying / pathology. Retrospective Studies. Surveys and Questionnaires

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  • [ErratumIn] J Oral Maxillofac Surg. 2005 Dec;63(12):1786
  • (PMID = 15944979.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Fujita S, Seki S, Fujiwara M, Ikeda T: Midkine expression correlating with growth activity and tooth morphogenesis in odontogenic tumors. Hum Pathol; 2008 May;39(5):694-700
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  • There was no difference in positive rate and intensity of MK between benign odontogenic tumors and their malignant counterparts.
  • Ameloblastoma showed MK localization in the peripheral columnar cells in budding processes from the parenchyma, which frequently expressed proliferating cell nuclear antigen.
  • MK was also preferentially expressed in keratinized cells in acanthomatous ameloblastoma and keratocystic odontogenic tumor.
  • [MeSH-minor] Adolescent. Adult. Aged. Ameloblastoma / pathology. Ameloblastoma / physiopathology. Female. Humans. Male. Middle Aged. Odontoma / pathology. Odontoma / physiopathology

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  • (PMID = 18329695.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MDK protein, human; 0 / Nerve Growth Factors
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90. Chuang FH, Wang WC, Shen YH, Lin LM, Chen YK: Occurrence of ameloblastoma in a patient with nasopharyngeal carcinoma after treatment by irradiation. Spec Care Dentist; 2010 Jan-Feb;30(1):27-8
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  • [Title] Occurrence of ameloblastoma in a patient with nasopharyngeal carcinoma after treatment by irradiation.
  • Ameloblastoma is the most common clinically significant epithelial odontogenic tumor, and is considered a benign but locally aggressive tumor of the craniofacial region.
  • We present the case history of a 46-year-old male patient who had a nasopharyngeal carcinoma (NPC) treated by irradiation, which was complicated by the occurrence of an ameloblastoma.
  • Following a review of the English language literature, this case history was identified as being the first report, to our knowledge, of the occurrence of ameloblastoma in a patient who had been irradiated for an NPC.
  • [MeSH-major] Ameloblastoma / diagnosis. Carcinoma / radiotherapy. Mandibular Neoplasms / diagnosis. Nasopharyngeal Neoplasms / radiotherapy. Neoplasms, Second Primary / diagnosis

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  • (PMID = 20051072.001).
  • [ISSN] 1754-4505
  • [Journal-full-title] Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
  • [ISO-abbreviation] Spec Care Dentist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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91. Bozza F, Marcelli VA, Pistilli R, Govoni FA, Marsico C: Maxillary ameloblastoma. Minerva Stomatol; 2006 Apr;55(4):215-22
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  • [Title] Maxillary ameloblastoma.
  • Maxillary ameloblastoma is a rare odontogenic neoplasm that is histologically benign and originates from epithelial cells present in bone tissue.
  • The risk, in particularly extensive forms, that the ameloblastoma will invade extra-maxillary structures such as the orbit, the pterygomaxillary fossa, the infratemporal fossa and the base of the skull, means that surgical treatment is difficult if it is to be oncologically radical while respecting function and aesthetics.
  • Our experience in treating 2 cases of maxillary ameloblastoma is reported.
  • [MeSH-major] Ameloblastoma / surgery. Maxillary Neoplasms / surgery

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  • (PMID = 16618996.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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92. Shetty DC, Urs AB, Godhi S, Gupta S: Classifying odontogenic keratocysts as benign cystic neoplasms: a molecular insight into its aggressiveness. J Maxillofac Oral Surg; 2010 Mar;9(1):30-4
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  • [Title] Classifying odontogenic keratocysts as benign cystic neoplasms: a molecular insight into its aggressiveness.
  • OBJECTIVE: The present study was conducted with the aim to evaluate the expression of p53 in Odontogenic Keratocyst (OKC) and Ameloblastoma to correlate with the aggressiveness of these lesions.
  • MATERIAL AND METHODS: Immunohistochemical (IHC) staining was performed using anti-p53 antibody in eighteen cases each of OKC and ameloblastoma.
  • RESULTS: p53 positivity was seen in all the cases of OKCs and ameloblastomas. p53 positive cells were seen predominantly in the suprabasal cell layer of OKC and in the peripheral pre-ameloblast like cells in ameloblastoma.
  • Total p53 count was significantly higher in ameloblastoma as compared to OKC.
  • CONCLUSION: The high p53 expression in OKC when compared with ameloblastoma, acknowledges OKC as an aggressive lesion and hence a more aggressive treatment modality is recommended.

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  • (PMID = 23139563.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453704
  • [Keywords] NOTNLM ; Aggressiveness / Ameloblastoma / Intensity / Odontogenic keratocyst / p53
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93. Nakano K, Siar CH, Tsujigiwa H, Nagatsuka H, Nagai N, Kawakami T: Notch signaling in benign and malignant ameloblastic neoplasms. Eur J Med Res; 2008 Oct 27;13(10):476-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Notch signaling in benign and malignant ameloblastic neoplasms.
  • BACKGROUND: In general, Notch is a representative signal which controls morphosis and differentiation of cells, but its role in human odontogenic neoplasms, especially in ameloblastoma and its malignant counterpart, ameloblastic carcinoma, is not known.
  • METHODS: We examined Notch1 peptide and its gene (mRNA) in an ameloblastoma (case 1: 27-year-old female, right mandibular tumor) and an ameloblastic carcinoma (case 2: 93-year-old female, right mandibular tumor), using immunohistochemistry (IHC) and in situ hybridization (ISH) techniques.
  • CONCLUSIONS: Notch signaling plays some role in cytological differentiation or acquisition of tissue specific characteristics in neoplastic cells of odontogenic neoplasms, including ameloblastoma and ameloblastic carcinoma.
  • [MeSH-major] Ameloblastoma / genetics. Ameloblastoma / metabolism. Mandibular Neoplasms / genetics. Mandibular Neoplasms / metabolism. Receptor, Notch1 / genetics. Receptor, Notch1 / metabolism

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  • (PMID = 19008176.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / NOTCH1 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Receptor, Notch1
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94. Bucur A, Dincă O, Totan C, Ghită V: [Inferior hemiarthroplasty of the temporo-mandibular joint with articulated condylar prosthesis type Stryker]. Chirurgia (Bucur); 2007 Jul-Aug;102(4):487-90
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  • This paperwork presents our experience on four cases in the reconstruction of the mandible together with the inferior arthroplasty of the temporo-mandibular joint, after the resection of extended benign tumors of the mandible, based on fibular free vascularized grafts having attached a Stryker titanium condylar prosthesis reconstructing the inferior segment of the temporo-mandibular joint.
  • [MeSH-minor] Ameloblastoma / surgery. Humans. Male. Mandibular Condyle / surgery. Mandibular Neoplasms / surgery. Mandibular Prosthesis Implantation. Middle Aged. Reconstructive Surgical Procedures. Titanium. Treatment Outcome

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  • (PMID = 17966949.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] D1JT611TNE / Titanium
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95. Kelly JM, Belding BA, Schaefer AK: Acanthomatous ameloblastoma in dogs treated with intralesional bleomycin. Vet Comp Oncol; 2010 Jun;8(2):81-6
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  • [Title] Acanthomatous ameloblastoma in dogs treated with intralesional bleomycin.
  • Acanthomatous ameloblastoma (AA) is a benign gingival tumour that often invades bone.
  • [MeSH-major] Ameloblastoma / veterinary. Antibiotics, Antineoplastic / therapeutic use. Bleomycin / therapeutic use. Dog Diseases / drug therapy. Gingival Neoplasms / veterinary

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  • (PMID = 20579320.001).
  • [ISSN] 1476-5829
  • [Journal-full-title] Veterinary and comparative oncology
  • [ISO-abbreviation] Vet Comp Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin
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96. Eckardt AM, Kokemüller H, Flemming P, Schultze A: Recurrent ameloblastoma following osseous reconstruction--a review of twenty years. J Craniomaxillofac Surg; 2009 Jan;37(1):36-41
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  • [Title] Recurrent ameloblastoma following osseous reconstruction--a review of twenty years.
  • BACKGROUND: The adequate therapy of ameloblastoma may require a compromise between the least destructive treatment possible of a benign tumour and a sufficiently radical method to prevent recurrences.
  • The primary reconstruction of bones and/or soft tissues, which is likely to be performed especially for benign processes is threatened by recurrences.
  • [MeSH-major] Ameloblastoma / pathology. Jaw Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Reconstructive Surgical Procedures

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  • (PMID = 19022680.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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97. Siar CH, Nakano K, Han PP, Nagatsuka H, Ng KH, Kawakami T: Differential expression of Notch receptors and their ligands in desmoplastic ameloblastoma. J Oral Pathol Med; 2010 Aug 1;39(7):552-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential expression of Notch receptors and their ligands in desmoplastic ameloblastoma.
  • The ameloblastoma, a benign odontogenic epithelial neoplasm, histologically recapitulates the enamel organ at bell stage.
  • Notch has been detected in the plexiform and follicular ameloblastoma.
  • Its activity in the desmoplastic ameloblastoma is unknown.
  • METHOD: Notch1-4 and their ligands (Jagged1, Jagged2 and Delta1) were examined immunohistochemically in 10 cases of desmoplastic ameloblastoma.
  • RESULTS: Ameloblastoma tumor epithelium demonstrated positive expression for Notch1 (n = 5/10), Notch3 (n = 8/10), Notch4 (n = 10/10), Jagged1 (n = 6/10) and Delta1 (n = 5/10), but no reactivity for Notch2 (n = 10/10) and Jagged2 (10/10).
  • CONCLUSIONS: These findings suggest that Notch receptors and their ligands may play differing roles during the development of the desmoplastic ameloblastoma with Notch4 probably playing a greater role in the acquisition of tissue-specific cellular characteristics in the desmoplastic ameloblastoma.
  • [MeSH-major] Ameloblastoma / pathology. Receptors, Notch / analysis

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  • (PMID = 20337864.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / JAG2 protein, human; 0 / Ligands; 0 / Membrane Proteins; 0 / NOTCH1 protein, human; 0 / NOTCH2 protein, human; 0 / NOTCH3 protein, human; 0 / NOTCH4 protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptor, Notch1; 0 / Receptor, Notch2; 0 / Receptors, Notch; 0 / delta protein; 134324-36-0 / Serrate proteins
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98. Li J, Sun J, He Y, Weng YQ, Jiang JD: [Axial split osteotomy of free fibular flap for mandibular angle reconstruction: a clinical study]. Shanghai Kou Qiang Yi Xue; 2005 Aug;14(4):355-8, 369
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  • 11 patients with benign tumors (8 ameloblastomas and 3 odontogenic keratocyst), 3 patients with osteoradionecrosis, and 2 patients with secondary mandibular deformity were included.
  • [MeSH-minor] Adult. Ameloblastoma / surgery. Female. Fibula. Humans. Jaw Neoplasms / surgery. Male. Mandible. Middle Aged. Osteoradionecrosis / surgery. Young Adult

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  • (PMID = 16155697.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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99. Reichart PA, Jundt G: [Benign epithelial odontogenic tumors]. Pathologe; 2008 May;29(3):175-6, 178-88
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  • [Title] [Benign epithelial odontogenic tumors].
  • The group of benign epithelial odontogenic tumors consists of the four member types of the ameloblastoma family (solid/multicystic, extraosseous/peripheral, desmoplastic, unicystic), squamous odontogenic tumors, calcifying odontogenic tumors, adenomatoid odontogenic tumors, and keratocystic odontogenic tumors, the former "keratocysts" that were recently reclassified by the World Health Organization and are now regarded as tumors.
  • The latter are by far the most frequent tumors in this group, followed by solid/multicystic ameloblastoma.
  • [MeSH-minor] Ameloblastoma / classification. Ameloblastoma / pathology. Ameloblastoma / surgery. Cementoma / classification. Cementoma / pathology. Cementoma / surgery. Diagnosis, Differential. Humans. Jaw / pathology. Jaw / surgery. Prognosis. Tomography, X-Ray Computed

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  • (PMID = 18389236.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] Adenoameloblastoma
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100. Moreira PR, Guimarães MM, Gomes CC, Diniz MG, Brito JA, de Castro WH, Gomez RS: Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours. Arch Oral Biol; 2009 Oct;54(10):893-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: The benign epithelial odontogenic tumours constitute a group of lesions derived from epithelial elements of the tooth-forming apparatus.
  • This group includes lesions of different biological behaviour, such as ameloblastoma, calcifying cystic odontogenic tumour (CCOT) and adenomatoid odontogenic tumour (AOT).
  • DESIGN: Methylation-specific polymerase chain reaction (MSP) was used to evaluate the presence of methylation in 13 samples of ameloblastoma, six samples of CCOT, three samples of AOT and 14 samples of dental follicles, included as control.
  • In ameloblastoma, the highest methylated genes were P16 and P21, while in CCOT the P21 and RB1 genes were the most commonly methylated genes.
  • [MeSH-minor] Adenoma / genetics. Adenoma / metabolism. Ameloblastoma / genetics. Ameloblastoma / metabolism. Dental Sac / metabolism. Epithelial Cells / metabolism. Humans. Odontogenic Cyst, Calcifying / genetics. Odontogenic Cyst, Calcifying / metabolism. Polymerase Chain Reaction / methods

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  • (PMID = 19679296.001).
  • [ISSN] 1879-1506
  • [Journal-full-title] Archives of oral biology
  • [ISO-abbreviation] Arch. Oral Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA, Neoplasm; 0 / Neoplasm Proteins
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