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1. Huang D, Sumegi J, Dal Cin P, Reith JD, Yasuda T, Nelson M, Muirhead D, Bridge JA: C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes Chromosomes Cancer; 2010 Sep;49(9):810-8
SciCrunch. HGNC: Data: Gene Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondroid lipoma, a rare benign adipose tissue tumor, may histologically resemble myxoid liposarcoma or extraskeletal myxoid chondrosarcoma, but is genetically distinct.

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  • [Copyright] (c) 2010 Wiley-Liss, Inc.
  • [Cites] Biochim Biophys Acta. 2001 May 28;1519(1-2):13-29 [11406267.001]
  • [Cites] Genes Chromosomes Cancer. 2009 Dec;48(12):1051-6 [19760602.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Mar;141(2):164-8 [12606137.001]
  • [Cites] Mol Cell Biol. 2003 Sep;23(18):6597-608 [12944485.001]
  • [Cites] J Biol Chem. 2003 Oct 24;278(43):41977-87 [14565952.001]
  • [Cites] Nat Genet. 2004 Jan;36(1):40-5 [14702039.001]
  • [Cites] Virchows Arch. 2004 Feb;444(2):208-10 [14722764.001]
  • [Cites] Cancer Genet Cytogenet. 2004 Apr 15;150(2):93-115 [15066317.001]
  • [Cites] Cancer Genet Cytogenet. 2004 May;151(1):87-9 [15120917.001]
  • [Cites] Am J Surg Pathol. 1993 Nov;17(11):1103-12 [8214255.001]
  • [Cites] Int J Cancer. 1994 Aug 15;58(4):503-5 [8056446.001]
  • [Cites] Genes Chromosomes Cancer. 1995 Mar;12(3):220-3 [7536462.001]
  • [Cites] Nat Genet. 1995 Aug;10(4):436-44 [7670494.001]
  • [Cites] Skeletal Radiol. 1996 Aug;25(6):592-5 [8865499.001]
  • [Cites] Am J Clin Pathol. 1998 Nov;110(5):660-70 [9802353.001]
  • [Cites] Mod Pathol. 1999 Jan;12(1):88-91 [9950168.001]
  • [Cites] Am J Pathol. 1999 Jul;155(1):61-6 [10393837.001]
  • [Cites] Am J Surg Pathol. 1999 Oct;23(10):1300-4 [10524534.001]
  • [Cites] Am J Hematol. 2005 May;79(1):43-5 [15849773.001]
  • [Cites] Biochem Biophys Res Commun. 2006 Feb 10;340(2):476-81 [16375854.001]
  • [Cites] Lab Invest. 2006 Jun;86(6):547-56 [16607381.001]
  • [Cites] Genes Chromosomes Cancer. 2008 Jul;47(7):558-64 [18383210.001]
  • [Cites] Cancer Genet Cytogenet. 2008 Jun;183(2):121-4 [18503832.001]
  • [Cites] J Orthop Sci. 2008 May;13(3):273-82 [18528664.001]
  • [Cites] Mod Pathol. 2008 Nov;21(11):1311-9 [18604193.001]
  • [Cites] Hum Pathol. 2009 Sep;40(9):1296-303 [19386349.001]
  • [Cites] Nat Genet. 2001 Jul;28(3):220-1 [11431691.001]
  • (PMID = 20607705.001).
  • [ISSN] 1098-2264
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA036727-24S59009; United States / NCI NIH HHS / CA / 5 P30 CA036727-2452; United States / NCI NIH HHS / CA / P30 CA036727-24S59009; United States / NCI NIH HHS / CA / U-10-CA98543-091
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MKL2 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Transcription Factors
  • [Other-IDs] NLM/ NIHMS203810; NLM/ PMC2904421
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2. Honoki K, Morita K, Kasai T, Fujii H, Kido A, Tsukamoto S, Nonomura A, Tanaka Y: Hibernoma of the axillary region: a rare benign adipocytic tumor. Rare Tumors; 2010;2(1):e7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hibernoma of the axillary region: a rare benign adipocytic tumor.
  • Hibernoma is a rare benign tumor considered to arise from remnants of fetal brown adipose tissue.
  • However, unlike lipomas, MRI findings sometimes mislead clinicians to diagnose a malignant neoplasm.

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  • (PMID = 21139952.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994483
  • [Keywords] NOTNLM ; adipocytic tumor / brown fat / hibernoma
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3. Wells WA, Wang X, Daghlian CP, Paulsen KD, Pogue BW: Phase contrast microscopy analysis of breast tissue: differences in benign vs. malignant epithelium and stroma. Anal Quant Cytol Histol; 2009 Aug;31(4):197-207
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase contrast microscopy analysis of breast tissue: differences in benign vs. malignant epithelium and stroma.
  • OBJECTIVE: To assess how optical scatter properties in breast tissue, as measured by phase contrast microscopy and interpreted pathophysiologically, might be exploited as a diagnostic tool to differentiate cancer from benign tissue.
  • STUDY DESIGN: We evaluated frozen human breast tissue sections of adipose tissue, normal breast parenchyma, benign fibroadenoma tumors and noninvasive and invasive malignant cancers by phase contrast microscopy through quantification of grayscale values, using multiple regions of interest (ROI).
  • RESULTS: Stroma demonstrated significantly higher scatter intensity than did epithelium, with lower scattering in tumor-associated stroma as compared with normal or benign-associated stroma.
  • Measures were comparable for invasive and noninvasive malignant tumors but were higher than those found in benign tumors and were lowest in adipose tissue.
  • CONCLUSION: Significant differences were found in scatter coefficient properties of epithelium and stroma across diagnostic categories of breast tissue, particularly between benign and malignant-associated stroma.

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  • [Cites] J Biomed Opt. 2000 Apr;5(2):221-8 [10938787.001]
  • [Cites] Gastroenterology. 2000 Sep;119(3):677-82 [10982761.001]
  • [Cites] Biophys J. 2002 Apr;82(4):2256-64 [11916880.001]
  • [Cites] Int J Cancer. 2003 May 20;105(1):53-60 [12672030.001]
  • [Cites] Cancer Res. 2003 Jul 1;63(13):3556-9 [12839941.001]
  • [Cites] Radiology. 2004 May;231(2):571-80 [15128998.001]
  • [Cites] Anal Quant Cytol Histol. 2004 Jun;26(3):166-74 [15218693.001]
  • [Cites] Phys Med Biol. 2004 Aug 21;49(16):3573-83 [15446788.001]
  • [Cites] Pathol Res Pract. 1984 Sep;179(1):61-6 [6504769.001]
  • [Cites] Surg Gynecol Obstet. 1987 Dec;165(6):523-9 [2825366.001]
  • [Cites] J Dermatol Surg Oncol. 1993 Sep;19(9):869-74 [7690052.001]
  • [Cites] Cancer Res. 2000 May 1;60(9):2497-503 [10811131.001]
  • [Cites] Radiology. 2000 Mar;214(3):895-901 [10715065.001]
  • [Cites] Am J Surg Pathol. 1995 Nov;19(11):1267-71 [7573688.001]
  • [Cites] Radiology. 2007 May;243(2):350-9 [17400760.001]
  • [Cites] Opt Lett. 2007 Apr 15;32(8):933-5 [17375158.001]
  • [Cites] J Surg Oncol. 1997 Dec;66(4):248-53 [9425328.001]
  • [Cites] Ann Surg Oncol. 1998 Apr-May;5(3):220-6 [9607622.001]
  • [Cites] Phys Med Biol. 1998 Sep;43(9):2555-67 [9755945.001]
  • [Cites] Phys Med Biol. 1998 Oct;43(10):2845-52 [9814522.001]
  • [Cites] J Biomed Opt. 2004 Nov-Dec;9(6):1122-8 [15568931.001]
  • [Cites] Biophys J. 2005 Apr;88(4):2929-38 [15653724.001]
  • [Cites] PLoS Biol. 2005 Jun;3(6):e187 [15869330.001]
  • [Cites] Opt Lett. 2005 Jun 1;30(11):1354-6 [15981531.001]
  • [Cites] J Biomed Opt. 2006 Nov-Dec;11(6):064007 [17212530.001]
  • [Cites] Histopathology. 2007 Feb;50(3):338-47 [17257129.001]
  • (PMID = 19736867.001).
  • [ISSN] 0884-6812
  • [Journal-full-title] Analytical and quantitative cytology and histology
  • [ISO-abbreviation] Anal. Quant. Cytol. Histol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U54 CA105480-010002; United States / NCI NIH HHS / CA / U54 CA105480; None / None / / U54 CA105480-010002; United States / NCI NIH HHS / CA / CA080139-09; United States / NCI NIH HHS / CA / P01 CA080139; United States / NCI NIH HHS / CA / P01 CA080139-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS183687; NLM/ PMC2857332
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4. Wilke LG, Brown JQ, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Geradts J, Ramanujam N: Rapid noninvasive optical imaging of tissue composition in breast tumor margins. Am J Surg; 2009 Oct;198(4):566-74
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  • [Title] Rapid noninvasive optical imaging of tissue composition in breast tumor margins.
  • Our objective is to develop an optically based technology which can differentiate benign from malignant breast tissues intraoperatively through differences in tissue composition factors.
  • Optical images are transformed into tissue composition maps with parameters of total hemoglobin concentration, b-carotene concentration and scattering.
  • Within 34 specimens with pathologically confirmed positive margins, the ratio map of b-carotene/scattering showed the most significant difference reflecting a decrease in adipose and an increase in cell density within malignant margins (p=.002).
  • CONCLUSIONS: We present a novel optical spectral imaging device that provides a rapid, non-destructive assay of the tissue composition of breast tumor margins.

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  • [Cites] Arch Pathol Lab Med. 2002 Jul;126(7):846-8 [12088456.001]
  • [Cites] Curr Opin Biotechnol. 2009 Feb;20(1):119-31 [19268567.001]
  • [Cites] Am J Surg. 2002 Nov;184(5):383-93 [12433599.001]
  • [Cites] Cancer. 2003 Aug 15;98(4):697-702 [12910512.001]
  • [Cites] CA Cancer J Clin. 1999 May-Jun;49(3):159-77 [10445015.001]
  • [Cites] Eur J Surg Oncol. 2004 Dec;30(10):1058-64 [15522551.001]
  • [Cites] AJR Am J Roentgenol. 2005 Jan;184(1):324-9 [15615996.001]
  • [Cites] Am Surg. 2005 Jan;71(1):22-7; discussion 27-8 [15757052.001]
  • [Cites] J Am Coll Surg. 2005 Aug;201(2):194-8 [16038815.001]
  • [Cites] Am J Surg Pathol. 2005 Dec;29(12):1625-32 [16327435.001]
  • [Cites] Lancet. 2005 Dec 17;366(9503):2087-106 [16360786.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1062-71 [16512550.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1072-8 [16512551.001]
  • [Cites] JAMA. 2006 Jun 7;295(21):2492-502 [16757721.001]
  • [Cites] Am J Surg. 2006 Oct;192(4):509-12 [16978962.001]
  • [Cites] Am J Surg. 2006 Oct;192(4):538-40 [16978970.001]
  • [Cites] Ann Surg Oncol. 2007 Apr;14(4):1458-71 [17260108.001]
  • [Cites] Ann Surg Oncol. 2007 Oct;14(10):2953-60 [17674109.001]
  • [Cites] Ann Surg Oncol. 2007 Nov;14(11):3133-40 [17653798.001]
  • [Cites] J Am Coll Surg. 2008 Jan;206(1):76-82 [18155571.001]
  • [Cites] Ann Surg Oncol. 2008 May;15(5):1297-303 [18259820.001]
  • [Cites] Ann Surg Oncol. 2008 May;15(5):1271-2 [18320287.001]
  • [Cites] Cancer. 2008 May 1;112(9):1923-31 [18327818.001]
  • [Cites] J Biomed Opt. 2008 Mar-Apr;13(2):024012 [18465975.001]
  • [Cites] J Am Coll Surg. 2008 Jun;206(3):1116-21 [18501808.001]
  • [Cites] J Biomed Opt. 2008 May-Jun;13(3):034015 [18601560.001]
  • [Cites] Ann Surg Oncol. 2008 Sep;15(9):2542-9 [18618180.001]
  • [Cites] Am J Surg. 2008 Oct;196(4):556-8 [18809063.001]
  • [Cites] World J Surg. 2008 Dec;32(12):2599-606 [18836763.001]
  • [Cites] Eur J Surg Oncol. 2009 Jan;35(1):32-7 [18539425.001]
  • [Cites] Breast Cancer Res Treat. 2009 Jan;113(2):397-402 [18386174.001]
  • [Cites] J Biomed Opt. 2009 Jan-Feb;14(1):014024 [19256712.001]
  • [Cites] J Clin Oncol. 2009 Apr 1;27(10):1615-20 [19255332.001]
  • [Cites] Cancer Res. 2009 Apr 1;69(7):2919-26 [19293184.001]
  • [Cites] Cancer. 2009 Apr 15;115(8):1669-79 [19170229.001]
  • [Cites] Am J Surg. 2002 Aug;184(2):89-93 [12169349.001]
  • (PMID = 19800470.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / UL1 RR024128; United States / NCRR NIH HHS / RR / UL1 RR024128-01; United States / NCRR NIH HHS / RR / 1UL1 RR024128-01
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS137679; NLM/ PMC2764289
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5. Alexaki VI, Notas G, Pelekanou V, Kampa M, Valkanou M, Theodoropoulos P, Stathopoulos EN, Tsapis A, Castanas E: Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development. J Immunol; 2009 Nov 1;183(9):5948-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development.
  • Adipose tissue represents a rich source of multipotent stem cells.
  • Our view of adipose tissue has recently changed, establishing adipocytes as new members of the immune system, as they produce a number of proinflammatory cytokines (such as IL-6 and TNFalpha and chemokines, in addition to adipokines (leptin, adiponectin, resistin) and molecules associated with the innate immune system.
  • In this paper, we report the differential expression of TNF-superfamily members B cell activating factor of the TNF Family (BAFF), a proliferation inducing ligand (APRIL), and TNF-like weak inducer of apoptosis (TWEAK) in immature-appearing and mature adipocytes and in benign and malignant adipose tissue-derived tumors.
  • We further report the existence of functional BCMA, TACI, and Fn14 receptors and their ligands BAFF, APRIL, and TWEAK on adipose tissue-derived mesenchymal cells, their interaction modifying the rate of adipogenesis.
  • [MeSH-major] Adipocytes / immunology. Adipocytes / metabolism. B-Cell Activating Factor / biosynthesis. B-Cell Activation Factor Receptor / biosynthesis. B-Cell Maturation Antigen / biosynthesis. Receptors, Tumor Necrosis Factor / biosynthesis. Transmembrane Activator and CAML Interactor Protein / biosynthesis. Tumor Necrosis Factor Ligand Superfamily Member 13 / biosynthesis. Tumor Necrosis Factors / biosynthesis
  • [MeSH-minor] Adipose Tissue / cytology. Adipose Tissue / immunology. Adipose Tissue / metabolism. Adipose Tissue / pathology. Cell Differentiation / immunology. Cells, Cultured. Humans. Tumor Cells, Cultured

  • Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 19828625.001).
  • [ISSN] 1550-6606
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / B-Cell Activating Factor; 0 / B-Cell Activation Factor Receptor; 0 / B-Cell Maturation Antigen; 0 / Receptors, Tumor Necrosis Factor; 0 / TNFRSF13B protein, human; 0 / TNFRSF13C protein, human; 0 / TNFRSF17 protein, human; 0 / TNFSF12 protein, human; 0 / TNFSF13B protein, human; 0 / TWEAK receptor; 0 / Transmembrane Activator and CAML Interactor Protein; 0 / Tumor Necrosis Factor Ligand Superfamily Member 13; 0 / Tumor Necrosis Factors
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6. Nord KH, Magnusson L, Isaksson M, Nilsson J, Lilljebjörn H, Domanski HA, Kindblom LG, Mandahl N, Mertens F: Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma. Proc Natl Acad Sci U S A; 2010 Dec 7;107(49):21122-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma.
  • Hibernomas are benign tumors with morphological features resembling brown fat.
  • Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor suppressor genes that are located 3 Mb apart and that underlie the hereditary syndromes pituitary adenoma predisposition and multiple endocrine neoplasia type I.
  • Simultaneous loss of two tumor suppressor genes has not previously been shown to result from a neoplasia-associated translocation.
  • Furthermore, in contrast to the prevailing assumption that benign tumors harbor relatively few genetic aberrations, the present analyses demonstrate that a considerable number of chromosome breaks are involved in the pathogenesis of hibernoma.
  • [MeSH-major] Gene Deletion. Genes, Tumor Suppressor. Intracellular Signaling Peptides and Proteins / genetics. Lipoma / genetics. Multiple Endocrine Neoplasia Type 1 / genetics
  • [MeSH-minor] Adipose Tissue, Brown. Chromosome Aberrations. Gene Expression Regulation, Neoplastic. Humans. Peroxisome Proliferator-Activated Receptors / genetics. Up-Regulation


7. Changizi V, Oghabian MA, Speller R, Sarkar S, Kheradmand AA: Application of small angle X-ray scattering (SAXS) for differentiation between normal and cancerous breast tissue. Int J Med Sci; 2005;2(3):118-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Application of small angle X-ray scattering (SAXS) for differentiation between normal and cancerous breast tissue.
  • These interferences carry information about the molecular structure of the tissue and hence can be used to identify changes that occur due to cancer.
  • The optimum scattering angle, determined from a series of measurements on adipose breast tissue at several angles from 4 to 7.3 degrees, was found to be 6.5 degrees.
  • Once optimized the system was used to measure the diffraction profiles (corrected scattered intensity versus momentum transfer) of a total of 99 breast tissue samples.
  • The samples were both normal and tumour samples.
  • RESULTS: Adipose tissue showed a sharp, high intensity peak at low momentum transfer values of approximately 1.1nm-1.
  • Adipose tissue, mixed tissue (adipose & fibroglandular) and tumor have peaks at different values of momentum transfer that can be used to identify the tissue.
  • Benign and malignant breast tissues can also be differentiated by both peak positions and peak heights.
  • It was also observed that the results were reproducible even after the tissue had been preserved at liquid nitrogen temperatures.
  • CONCLUSION: We were able to differentiate between normal, benign and malignant breast tissues by using energy dispersive small angle x-ray scattering.

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  • [Cites] Phys Med Biol. 1999 Jul;44(7):1791-802 [10442713.001]
  • [Cites] Int J Cancer. 1988 Feb 15;41(2):184-97 [3338870.001]
  • [Cites] Phys Med Biol. 1991 Jan;36(1):7-18 [2006216.001]
  • [Cites] Phys Med Biol. 2002 Feb 21;47(4):577-92 [11900192.001]
  • (PMID = 16007264.001).
  • [ISSN] 1449-1907
  • [Journal-full-title] International journal of medical sciences
  • [ISO-abbreviation] Int J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Other-IDs] NLM/ PMC1168877
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8. Gurel D, Kargi A, Lebe B: Pedunculated cutaneous spindle cell/pleomorphic lipoma. J Cutan Pathol; 2010 Sep;37(9):e57-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Spindle cell/pleomorphic lipoma is an infrequently seen benign adipose tissue tumor.
  • This tumor, mostly arising from the subcutaneous tissue, usually affects male patients and occurs in back, shoulders, head and neck area.
  • [MeSH-minor] Antigens, CD34 / metabolism. Biomarkers, Tumor / metabolism. Dermis / pathology. Humans. Male. Vimentin / metabolism

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  • (PMID = 19678825.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Vimentin
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9. Fernández-Sueiro JL, Pinto JA, Blanco FJ, Freire M, Veiga JA, Galdo F, González-Gay MA: Multiple parosteal lipoma associated to polyarthritis. Joint Bone Spine; 2006 Mar;73(2):202-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Parosteal lipoma is a benign adipose tissue tumor situated directly in the bone cortex.
  • We describe a patient who presented with polyarthritis associated with multiple parosteal lipomatous involvement.
  • A tissue sample from the distal portion of the forearm confirmed the presence of cumulative fat tissue with nodes of esteatonecrosis.
  • [MeSH-minor] Adipose Tissue / pathology. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Drug Therapy, Combination. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Prednisone / therapeutic use. Tomography, X-Ray Computed. Wrist / pathology. Wrist / radiography

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  • (PMID = 16226479.001).
  • [ISSN] 1297-319X
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; VB0R961HZT / Prednisone
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10. Speer AL, Schofield DE, Wang KS, Shin CE, Stein JE, Shaul DB, Mahour GH, Ford HR: Contemporary management of lipoblastoma. J Pediatr Surg; 2008 Jul;43(7):1295-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Lipoblastoma is a rare, benign, adipose tissue tumor.
  • [MeSH-major] Neoplasms, Adipose Tissue / surgery. Soft Tissue Neoplasms / surgery

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  • (PMID = 18639685.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Scariot R, Giovanini AF, Torres-Pereira CC, Piazzetta CM, Costa DJ, Rebellato NL, Müller PR: Massive growth of an intraoral lipoma. J Contemp Dent Pract; 2008;9(7):115-21
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  • BACKGROUND: Lipoma, a benign tumor of adipose tissue, is rarely seen in the oral cavity.
  • A clinical diagnosis of lipoma was established, and the treatment consisted of complete excision of the mass under local anesthesia.
  • CLINICAL SIGNIFICANCE: This case report emphasizes the slow growth and benign characteristics of oral lipomas.

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  • (PMID = 18997924.001).
  • [ISSN] 1526-3711
  • [Journal-full-title] The journal of contemporary dental practice
  • [ISO-abbreviation] J Contemp Dent Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Akbulut M, Zekioglu O, Terek MC, Ozdemir N: Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor. Arch Gynecol Obstet; 2008 Sep;278(3):283-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor.
  • OBJECTIVE: Adenofibroma is a form of mixed mesodermal tumor in which epithelial and stromal components are benign, and usually arises in the endometrium of postmenopausal women.
  • We report a case of lipoadenofibroma of the endometrium that appeared as an intracavitary mass, which is very unusual because endometrioid adenofibroma rarely contains mature adipose tissue, only the second such case described in detail.
  • The endometrial polypoid mass was found to be a lipoadenofibroma composed predominantly of collagenated fibrous stroma populated by cystically dilated and occasionally crowded glands lined with proliferative endometrium, intermingled with abundant mature adipose tissue.
  • CONCLUSION: We suggest that uterine adenofibromas with lipomatous areas belong to the family of mixed tumor of Mullerian origin.
  • [MeSH-major] Adenofibroma / pathology. Endometrial Neoplasms / pathology. Mixed Tumor, Mullerian / pathology

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  • (PMID = 18236054.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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13. Nazeer T, Kee KH, Ro JY, Jennings TA, Ross J, Mian BM, Shen SS, Suh JH, Lee MJ, Ayala AG: Intraprostatic adipose tissue: a study of 427 whole mount radical prostatectomy specimens. Hum Pathol; 2009 Apr;40(4):538-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraprostatic adipose tissue: a study of 427 whole mount radical prostatectomy specimens.
  • Tumor Gleason grade and stage provide extremely valuable prognostic information and play an important role in therapeutic decision making and patient counseling.
  • A biopsy or radical prostatectomy specimen revealing carcinoma extending into extraprostatic tissue permits a T3 classification.
  • This is most easily recognized, particularly in a needle biopsy, when tumor is seen to invade the adipose tissue.
  • The existence of intraprostatic adipose tissue is somewhat controversial.
  • To investigate this, formalin-fixed paraffin-embedded whole-mount radical prostatectomy specimens from 427 patients with adenocarcinoma were evaluated for intraprostatic adipose tissue.
  • Intraprostatic adipose tissue was identified in 17 (3.98%) of cases.
  • In 13 cases, the fat was intimately associated with benign glands.
  • Intraprostatic adipose tissue was located in the peripheral zone in 15 cases and in the central zone in 2.
  • Intraprostatic adipose tissue, although uncommon, does exist.
  • The small size of foci of adipose tissue and its admixture with benign glands are useful morphologic clues in distinguishing it from extraprostatic fat.
  • [MeSH-major] Adenocarcinoma / pathology. Adipose Tissue / anatomy & histology. Prostatic Neoplasms / pathology

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  • [CommentIn] Hum Pathol. 2011 May;42(5):759 [21492748.001]
  • (PMID = 19121845.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Siddiqui MK, Jyoti, Singh S, Mehrotra PK, Singh K, Sarangi R: Comparison of some trace elements concentration in blood, tumor free breast and tumor tissues of women with benign and malignant breast lesions: an Indian study. Environ Int; 2006 Jul;32(5):630-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of some trace elements concentration in blood, tumor free breast and tumor tissues of women with benign and malignant breast lesions: an Indian study.
  • Fifty women residing in and around New Delhi, India and identified to have benign (25 nos.) and malignant (25 nos.) breast lesions were studied for the first time to access the association between environmental exposure to lead and risk of breast cancer and to determine the potential of changes in trace elements concentration as a diagnostic marker and/or its etiological involvement in the disease.
  • Blood, tumor tissue and breast adipose tissue from tumor free area from each patient of the two groups, collected at the time of lumpectomy or mastectomy (only blood sample was collected from disease free control group), were analyzed to determine the concentration of Pb, Zn, Cu, Fe and Ca using Atomic Absorption Spectrometry.
  • Blood lead was significantly higher in malignant cases than in those of benign and control (p<0.05 each).
  • Lead level was also higher in tumor tissue when compared with their respective normal tumor free breast tissue, though non-significant, in both benign and malignant cases.
  • Interestingly, Zn, Fe, and Ca levels were higher in blood of malignant cases than in those of their benign counterparts.
  • Furthermore, these metals were also higher in tumor of malignant and benign cases as compared to normal tumor free breast tissue, many of them statistically significant (p<0.05/0.01/0.001).
  • However, Cu level was insignificantly lower in the blood and tumor tissue of malignant cases when compared with their benign counterparts while it was significantly higher (p<0.05) in tumor of benign cases when compared with those of their respective normal tumor free breast tissue.
  • There were statistically significant correlations between lead and trace element levels only in normal tumor free breast tissue of benign and malignant cases (r=0.41-0.73; p<0.05-0.001) but neither in blood nor tumor tissue of the two groups.
  • Further, modulation of trace elements level in both benign and malignant breast diseases patients may be of potential to be used as diagnostic marker of the disease process and its possible relationship etiologically.
  • [MeSH-major] Biomarkers, Tumor / blood. Breast Neoplasms / blood. Mammary Glands, Human / metabolism. Trace Elements / blood

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  • (PMID = 16580070.001).
  • [ISSN] 0160-4120
  • [Journal-full-title] Environment international
  • [ISO-abbreviation] Environ Int
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Trace Elements
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15. Durgun Y, Firat C, Miman MC, Kirimlioglu H: A rare benign laryngeal tumor: angiomyolipoma. J Craniofac Surg; 2010 Nov;21(6):1956-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare benign laryngeal tumor: angiomyolipoma.
  • Angiomyolipoma is a mesenchymal neoplasm containing adipose tissue, blood vessels, and smooth muscle fibers.
  • Arising most frequently in the kidney, the tumor may exceptionally be at the head and neck region.
  • The tumor was removed by an endolaryngeal approach.
  • [MeSH-major] Angiomyolipoma / diagnosis. Laryngeal Neoplasms / diagnosis
  • [MeSH-minor] Deglutition Disorders / diagnosis. Follow-Up Studies. Humans. Laryngoscopy. Male. Microsurgery. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 21119467.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Siddiqui MK, Anand M, Mehrotra PK, Sarangi R, Mathur N: Biomonitoring of organochlorines in women with benign and malignant breast disease. Environ Res; 2005 Jun;98(2):250-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biomonitoring of organochlorines in women with benign and malignant breast disease.
  • Blood, tumor, and surrounding adipose tissue of the breast were collected from the subjects with benign (control) and malignant breast (study) lesions and analyzed to determine organochlorine insecticides using a gas-liquid chromatograph equipped with an electron capture detector.
  • However, both total HCH and total DDT were higher in the tumor tissues of the controls than in those of the study group; gamma-HCH was significantly different (P<0.05).
  • The level of total HCH (alpha-HCH was significantly different, P<0.05) was higher in the breast adipose tissue of the study group, whereas total DDT was higher in the breast adipose tissue of the control group.
  • The distribution of known confounders of breast cancer including age, body mass index, age at menarche and menopause, duration of breast feeding, and family history related to breast disease did not differ significantly between benign and malignant groups.
  • [MeSH-minor] Adipose Tissue / metabolism. Adult. Age Factors. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Case-Control Studies. Chromatography, Gas. Female. Humans. Mammography. Middle Aged. Pilot Projects. Risk Factors. Tissue Distribution

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  • (PMID = 15820732.001).
  • [ISSN] 0013-9351
  • [Journal-full-title] Environmental research
  • [ISO-abbreviation] Environ. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Environmental Pollutants; 0 / Hydrocarbons, Chlorinated
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17. Bandyopadhyay S, Basturk O, Coban I, Thirabanjasak D, Liang H, Altinel D, Adsay NV: Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate. Am J Surg Pathol; 2009 Mar;33(3):425-9
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  • [Title] Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate.
  • The glandular units of invasive carcinoma are often well formed with well-polarized cells, appearing deceptively benign.
  • We recently noted isolated solitary ductal units (ISDs) in adipose tissue to be a reliable indicator of adenocarcinoma.
  • ISD was defined as a solitary gland lying individually in adipose tissue, either directly abutting adipocytes or separated from them by only a thin rim of fibromuscular tissue.
  • ISDs were often located in histologic sections taken for the evaluation of the retroperitoneal margin and pancreatic-free surfaces where adipose tissue is more abundant.
  • In conclusion, ISD lying in adipose tissue unaccompanied by other elements, present in 47.6% of pancreatic resections when peripancreatic soft tissues away from the tumor are sampled, is a very specific finding for carcinoma that may be instrumental in the diagnosis and staging of carcinoma as well as margin evaluation.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Pancreatitis / pathology

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  • (PMID = 19092633.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Bancroft LW, Kransdorf MJ, Peterson JJ, O'Connor MI: Benign fatty tumors: classification, clinical course, imaging appearance, and treatment. Skeletal Radiol; 2006 Oct;35(10):719-33

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign fatty tumors: classification, clinical course, imaging appearance, and treatment.
  • Lipoma is the most common soft-tissue tumor, with a wide spectrum of clinical presentations and imaging appearances.
  • Several subtypes are described, ranging from lesions entirely composed of mature adipose tissue to tumors intimately associated with nonadipose tissue, to those composed of brown fat.
  • The imaging appearance of these fatty masses is frequently sufficiently characteristic to allow a specific diagnosis.
  • However, in other cases, although a specific diagnosis is not achievable, a meaningful limited differential diagnosis can be established.
  • The purpose of this manuscript is to review the spectrum of benign fatty tumors highlighting the current classification system, clinical presentation and behavior, spectrum of imaging appearances, and treatment.
  • [MeSH-major] Neoplasms, Adipose Tissue / classification. Neoplasms, Adipose Tissue / diagnosis. Neoplasms, Adipose Tissue / therapy
  • [MeSH-minor] Diagnosis, Differential. Humans. Lipoma / classification. Lipoma / diagnosis. Lipoma / therapy. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • [Cites] JAMA. 1968 Jan 22;203(4):305 [5694112.001]
  • [Cites] Otolaryngol Head Neck Surg. 1985 Feb;93(1):109-12 [3920607.001]
  • [Cites] Am J Surg Pathol. 1985 Jan;9(1):7-14 [3970300.001]
  • [Cites] Skeletal Radiol. 1985;13(4):276-9 [4001970.001]
  • [Cites] West J Surg Obstet Gynecol. 1946 Mar;54:87-93 [21020330.001]
  • [Cites] J Korean Med Sci. 1988 Dec;3(4):163-7 [3267365.001]
  • [Cites] Cancer. 1975 Nov;36(5):1852-9 [1192370.001]
  • [Cites] Clin Radiol. 1996 Apr;51(4):295-7 [8617045.001]
  • [Cites] AJR Am J Roentgenol. 1994 Jul;163(1):162-4 [8010204.001]
  • [Cites] Arch Pathol Lab Med. 2001 Sep;125(9):1224-6 [11520278.001]
  • [Cites] Arch Dermatol. 1960 Dec;82:924-31 [13716236.001]
  • [Cites] Neurology. 1990 Aug;40(8):1246-50 [2166247.001]
  • [Cites] Radiology. 1982 Jul;144(1):121-4 [7089242.001]
  • [Cites] Skeletal Radiol. 1986;15(6):464-7 [3764475.001]
  • [Cites] Surg Gynecol Obstet. 1968 Jul;127(1):129-32 [4872533.001]
  • [Cites] Skeletal Radiol. 1994 Nov;23 (8):652-5 [7886477.001]
  • [Cites] Radiographics. 1991 Jan;11(1):81-106 [1996399.001]
  • [Cites] Am J Surg Pathol. 1991 Feb;15(2):121-5 [1703396.001]
  • [Cites] J Bone Joint Surg Am. 1966 Oct;48(7):1350-8 [5921790.001]
  • [Cites] Acta Orthop Scand. 1981 Jun;52(3):287-93 [7282321.001]
  • [Cites] Skeletal Radiol. 1996 Jul;25(5):493-6 [8837285.001]
  • [Cites] Skeletal Radiol. 2003 Sep;32(9):504-9 [12811424.001]
  • [Cites] Acta Radiol. 1992 Nov;33(6):554-5 [1333257.001]
  • [Cites] AJR Am J Roentgenol. 1980 Oct;135(4):781-7 [6778113.001]
  • [Cites] AJR Am J Roentgenol. 1992 Jun;158(6):1295-7 [1590127.001]
  • [Cites] J Bone Joint Surg Am. 1972 Sep;54(6):1262-6 [4652058.001]
  • [Cites] AJR Am J Roentgenol. 2003 Nov;181(5):1251-4 [14573414.001]
  • [Cites] Skeletal Radiol. 1995 Jan;24(1):72-3 [7709262.001]
  • [Cites] J Comput Assist Tomogr. 2002 Nov-Dec;26(6):1063-8 [12488762.001]
  • [Cites] Skeletal Radiol. 2001 Oct;30(10 ):590-5 [11685483.001]
  • [Cites] Am J Pathol. 1958 Nov-Dec;34(6):1149-59 [13583102.001]
  • [Cites] AJR Am J Roentgenol. 2003 May;180(5):1419-22 [12704061.001]
  • [Cites] J Bone Joint Surg Am. 1988 Feb;70(2):264-70 [3343272.001]
  • [Cites] Semin Diagn Pathol. 2001 Nov;18(4):238-49 [11757863.001]
  • [Cites] AJNR Am J Neuroradiol. 1996 Apr;17(4):713-9 [8730192.001]
  • [Cites] Cancer. 1974 Sep;34(3):720-7 [4855281.001]
  • [Cites] Magn Reson Imaging. 1998 May;16(4):445-8 [9665556.001]
  • [Cites] Clin Orthop Relat Res. 1986 Apr;(205):251-3 [3698384.001]
  • [Cites] Virchows Arch. 1997 Aug;431(2):83-94 [9293889.001]
  • [Cites] Orthop Rev. 1988 Nov;17(11):1083-5 [3205585.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] Radiology. 2002 Jul;224(1):99-104 [12091667.001]
  • [Cites] J Neurosurg. 2000 Apr;92(2 Suppl):214-6 [10763695.001]
  • [Cites] Skeletal Radiol. 1996 Aug;25(6):592-5 [8865499.001]
  • [Cites] Ann Plast Surg. 1988 Mar;20(3):277-9 [3358622.001]
  • [Cites] Acta Orthop Scand. 1983 Dec;54(6):929-34 [6670522.001]
  • [Cites] Hum Pathol. 1986 Dec;17(12):1285-7 [3793089.001]
  • [Cites] J Hand Surg Am. 1988 Jan;13(1):67-75 [3351231.001]
  • [Cites] J Pathol Bacteriol. 1954 Oct;68(2):511-8 [14354555.001]
  • [Cites] Cancer. 1983 Aug 1;52(3):567-74 [6861094.001]
  • [Cites] Br J Radiol. 1989 Feb;62(734):178-80 [2924101.001]
  • [Cites] Medicine (Baltimore). 1984 Jan;63(1):56-64 [6318013.001]
  • [Cites] Am J Surg Pathol. 1993 Nov;17(11):1103-12 [8214255.001]
  • [Cites] AJR Am J Roentgenol. 1993 Oct;161(4):837-8 [8372770.001]
  • [Cites] AJNR Am J Neuroradiol. 2003 May;24(5):1008-11 [12748114.001]
  • [Cites] J Comput Assist Tomogr. 1986 Jul-Aug;10 (4):696-8 [3734216.001]
  • (PMID = 16927086.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 65
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19. Previgliano CH, Sangster GP, Simoncini AA, Carbó AI, González E, Li B, D'Agostino H: Parosteal lipoma of the rib: a benign condition that mimics malignancy. J La State Med Soc; 2010 Jan-Feb;162(1):40-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parosteal lipoma of the rib: a benign condition that mimics malignancy.
  • They are composed of adipose tissue adjacent to the bone cortex and elicit bony reactive changes.
  • Albeit a benign condition, PL imaging findings may be misinterpreted as a malignant lesion.
  • Lipomas are benign tumors consisting of mature fat cells.
  • They are the most common mesenchymal neoplasias and account for 50% of all soft tissue tumors.
  • Musculoskeletal lipomatous lesions may be located in bones, soft tissues, and may also affect joint and tendon sheaths.
  • PL is a rare benign deep fatty-tissue tumor that arises contiguous to the periosteum without originating from it.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 20336957.001).
  • [ISSN] 0024-6921
  • [Journal-full-title] The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • [ISO-abbreviation] J La State Med Soc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Lasalandra C, Coviello M, Falco G, Divella R, Trojano G, Laterza AM, Quero C, Pepe V, Zito FA, Quaranta M: Serum vascular endothelial growth factor and adiponectin levels in patients with benign and malignant gynecological diseases. Int J Gynecol Cancer; 2010 May;20(4):507-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serum vascular endothelial growth factor and adiponectin levels in patients with benign and malignant gynecological diseases.
  • Adipose tissue is a major endocrine and it secretes hormones termed adipokines.
  • This study was designed to determine the serum VEGF and adiponectin levels in patients with benign and malignant gynecological diseases and if there was a correlation between serum VEGF and adiponectin.
  • Diagnosis of benign and malignant gynaecological diseases was established by biopsy.
  • RESULTS: Our results were analyzed on the basis of 2 different parameters: age and benign and malignant gynecological diseases of the patient.
  • Only for serum VEGF levels was a significant difference observed (P = 0.004) between patients with benign and malignant gynecological diseases.
  • A significantly inverse correlation between serum VEGF and adiponectin levels among patients with benign and malignant gynecological diseases was found.
  • CONCLUSIONS: This is one of the first report on adiponectin in benign and malignant gynecological diseases.
  • [MeSH-major] Adiponectin / blood. Biomarkers, Tumor / blood. Genital Diseases, Female / blood. Neoplasms / blood. Vascular Endothelial Growth Factor A / blood

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  • (PMID = 20442584.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adiponectin; 0 / Biomarkers, Tumor; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A
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21. McQueen C, Montgomery E, Dufour B, Olney MS, Illei PB: Giant hypopharyngeal atypical lipomatous tumor. Adv Anat Pathol; 2010 Jan;17(1):38-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant hypopharyngeal atypical lipomatous tumor.
  • Microscopically, they display an admixture of fibrovascular and adipose tissue that is coated by unremarkable squamous mucosa.
  • Here, we report a case that had scattered hyperchromatic cells and lipoblasts within the adipose tissue component.
  • In other anatomic sites similar appearing lesions have been interpreted as pedunculated liposarcomas/atypical lipomatous tumors that are more prone to local recurrences than classic giant fibrovascular polyps.
  • To confirm our suspicion of liposarcomatous differentiation, we performed immunohistochemistry for MDM2 and p53, 2 markers that are known to be negative in benign lipomatous lesions and positive in well-differentiated liposarcomas/atypical lipomatous tumors.
  • The scattered atypical hyperchromatic cells and the lipoblasts both exhibited strong nuclear staining for both markers and supported the diagnosis of pedunculated giant hypopharyngeal atypical lipomatous tumor.
  • [MeSH-minor] Humans. Immunohistochemistry. Male. Middle Aged. Polyps / diagnosis. Proto-Oncogene Proteins c-mdm2 / metabolism. Tumor Suppressor Protein p53 / metabolism

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  • (PMID = 20032637.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
  • [Number-of-references] 51
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22. Ozcan C, Görür K, Talas D, Aydin O: Intramuscular benign lipoma of the sternocleidomastoid muscle: a rare cause of neck mass. Eur Arch Otorhinolaryngol; 2005 Feb;262(2):148-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramuscular benign lipoma of the sternocleidomastoid muscle: a rare cause of neck mass.
  • Intramuscular benign lipoma commonly is found on the extremities, but is extremely rare in the head and neck region.
  • Intramuscular type lipomas arise between the muscle fibers and pass through the intermuscular septa, infiltrating the surrounding tissue.
  • CT examination revealed a lobulated, well-circumscribed 5.5x2.5-cm diameter mass with adipose tissue signal density inside the SCM muscle.
  • This rare entity should be considered in the differential diagnosis of intramuscularly located neck masses.
  • Complete removal of the tumor can only succeed if planned and performed after a thorough preoperative clinical and radiological assessment in order to prevent recurrences.

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  • [Cites] Otolaryngol Head Neck Surg. 2001 Dec;125(6):658-60 [11743474.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1988 Dec;114(12):1480-2 [3190880.001]
  • [Cites] J Oral Maxillofac Surg. 2002 Apr;60(4):449-50 [11928107.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1999 Jan 25;47(1):91-5 [10206400.001]
  • [Cites] J Laryngol Otol. 2002 May;116(5):395-7 [12081004.001]
  • [Cites] Cancer. 1974 Mar;33(3):732-8 [4815576.001]
  • [Cites] Head Neck Surg. 1980 Nov-Dec;3(2):145-68 [7002869.001]
  • [Cites] Laryngoscope. 1983 Feb;93(2):205-7 [6823193.001]
  • [Cites] Laryngoscope. 1978 May;88(5):839-48 [642677.001]
  • [Cites] J Oral Maxillofac Surg. 1991 Nov;49(11):1231-6 [1941342.001]
  • [Cites] AJNR Am J Neuroradiol. 1986 Jul-Aug;7(4):657-64 [3088944.001]
  • (PMID = 15197561.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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23. Nishihara E, Miyauchi A, Hirokawa M, Kudo T, Ohye H, Ito M, Kubota S, Fukata S, Amino N, Kuma K: Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature. Endocrine; 2006 Oct;30(2):231-6
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  • [Title] Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature.
  • Benign thyroid teratomas are rare in adolescents and adults.
  • We report on three cases of benign thyroid teratomas that presented as painful tumors in the neck after puberty.
  • The tumor adjacent to the thyroid in each case showed rapid enlargement with predominant cystic lesions within several months.
  • Ultrasonography and computed tomography revealed few findings suggesting the origin of the tumor.
  • The patients subsequently underwent resection of the tumor, and microscopic examination revealed various types of tissue including pancreas, adipose, cartilage, muscle, and skin, and the cystic wall was lined by gastric, intestinal, respiratory, and stratified squamous epithelium.
  • Surgical resection was curative, and subsequent histologic examination revealed mature benign teratomas of the thyroid.
  • The main characteristic of our cases presented the painful tumors due to the enlarged cystic formation lined by a variety of different types of epithelium, which agreed with previous cases of benign thyroid teratomas in adolescents and adults.
  • [MeSH-major] Pain / diagnosis. Teratoma / diagnosis. Thyroid Neoplasms / diagnosis. Thyroid Nodule / diagnosis
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Neoplasms / diagnosis

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  • [Cites] Arch Pathol Lab Med. 1984 Oct;108(10):835-7 [6206822.001]
  • [Cites] Acta Radiol. 2004 Feb;45(1):111-2 [15164790.001]
  • [Cites] Acta Pathol Jpn. 1986 Jun;36(6):935-43 [3766140.001]
  • [Cites] Hum Pathol. 1985 Jan;16(1):56-64 [2982716.001]
  • [Cites] Surgery. 1985 May;97(5):613-7 [3992484.001]
  • [Cites] J Pediatr Surg. 1988 Jun;23(6):583-91 [3047360.001]
  • [Cites] Br J Surg. 1959 Mar;46(199):466-72 [13651623.001]
  • [Cites] Am J Otolaryngol. 2000 Mar-Apr;21(2):112-5 [10758996.001]
  • [Cites] Eur J Pediatr Surg. 2004 Apr;14(2):117-9 [15185159.001]
  • [Cites] J Formos Med Assoc. 2005 Jul;104(7):514-7 [16091830.001]
  • [Cites] Surg Today. 1997;27(5):469-72 [9130356.001]
  • [Cites] Thorax. 1975 Oct;30(5):510-5 [1198389.001]
  • [Cites] Cancer. 2000 Mar 1;88(5):1149-58 [10699906.001]
  • [Cites] Am J Surg Pathol. 2005 May;29(5):700-6 [15832097.001]
  • [Cites] Surgery. 1986 Nov;100(5):932-7 [3775664.001]
  • [Cites] Am J Dis Child. 1967 Feb;113(2):222-4 [6019438.001]
  • [Cites] Ann Thorac Surg. 1991 Jan;51(1):110-2 [1985547.001]
  • [Cites] Ann Thorac Surg. 1992 Oct;54(4):741-3 [1384444.001]
  • [Cites] S Afr J Surg. 1966 Oct-Dec;4(4):181-5 [5977300.001]
  • [Cites] Teratology. 1974 Oct;10(2):111-8 [4428419.001]
  • (PMID = 17322585.001).
  • [ISSN] 1355-008X
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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24. Schmack I, Patel RM, Folpe AL, Wojno T, Zaldivar RA, Balzer B, Kang SJ, Weiss SW, Grossniklaus HE: Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. Am J Surg Pathol; 2007 Feb;31(2):193-8
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  • [Title] Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor.
  • Over the past several years, we have seen a number of cases in which this prolapsed fat was confused pathologically with a neoplasm of adipocytic lineage, specifically pleomorphic lipoma and atypical lipomatous neoplasm (well-differentiated liposarcoma).
  • We conclude that subconjunctival herniated orbital fat commonly contains multinucleated floretlike giant cells, fibrous septae, and Lochkern cells, features that may result in diagnostic confusion with pleomorphic lipoma and atypical lipomatous neoplasms.
  • Importantly, specific diagnostic features, such as aggregates of bland spindled cells associated with wiry collagen, as seen in pleomorphic lipoma, and enlarged hyperchromatic cells within fibrous septae, as in atypical lipomatous neoplasms, are entirely absent in herniated orbital fat.
  • [MeSH-major] Adipose Tissue / pathology. Conjunctiva / pathology. Conjunctival Diseases / pathology. Eye Neoplasms / diagnosis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbit / pathology
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adult. Aged. Aged, 80 and over. Biomarkers / metabolism. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prolapse. Tomography, X-Ray Computed

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  • (PMID = 17255763.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30-EY06360
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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25. Yamaguchi T, Takimoto T, Yamashita T, Kitahara S, Omura M, Ueda Y: Fat-containing variant of solitary fibrous tumor (lipomatous hemangiopericytoma) arising on surface of kidney. Urology; 2005 Jan;65(1):175
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  • [Title] Fat-containing variant of solitary fibrous tumor (lipomatous hemangiopericytoma) arising on surface of kidney.
  • Fat-containing variant of a solitary fibrous tumor is a recently recognized benign soft-tissue tumor that usually affects the thigh and retroperitoneum.
  • We report a 51-year-old woman with a fat-containing variant of a solitary fibrous tumor that is the first reported case involving a visceral organ.
  • The tumor was well delineated and seemed to arise from the renal capsule, radiographically and macroscopically.
  • The tumor microscopically mimicked a solitary fibrous tumor but exhibited focal aggregates of fat cells.
  • A fat-containing variant of a solitary fibrous tumor involving the kidney should be distinguished from spindle cell carcinoma, angiomyolipoma, gastrointestinal stromal tumor, and cellular schwannoma.
  • [MeSH-major] Adipose Tissue / pathology. Hemangiopericytoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Carcinoma, Renal Cell / diagnosis. Diagnosis, Differential. Female. Humans. Middle Aged. Nephrectomy. Tomography, X-Ray Computed

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  • (PMID = 15667897.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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26. Veinot JP: Cardiac tumors of adipocytes and cystic tumor of the atrioventricular node. Semin Diagn Pathol; 2008 Feb;25(1):29-38
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  • [Title] Cardiac tumors of adipocytes and cystic tumor of the atrioventricular node.
  • Lipomatous lesions of the heart and cystic tumor of the atrioventricular node are not common.
  • A pathologist will only rarely encounter these entities, and in the case of the atrioventricular node tumor, only if they examine the conduction system.
  • Most fatty lesions are not clinically significant; however, arrhythmias, blood flow obstruction, and valvular dysfunction may result from benign or malignant lipomatous tumors.
  • Cystic tumor of the atrioventricular node has been implicated in the causation of sudden cardiac death, and there has been much academic interest concerning its cell of origin.
  • [MeSH-major] Adipocytes / pathology. Atrioventricular Node / pathology. Heart Neoplasms / pathology. Neoplasms, Adipose Tissue / pathology

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  • (PMID = 18350920.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Sirvent N, Coindre JM, Maire G, Hostein I, Keslair F, Guillou L, Ranchere-Vince D, Terrier P, Pedeutour F: Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR. Am J Surg Pathol; 2007 Oct;31(10):1476-89
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  • [Title] Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR.
  • Atypical lipomatous tumor/well-differentiated liposarcomas and dedifferentiated liposarcomas are characterized by the amplification of MDM2 and CDK4 genes.
  • To evaluate the accuracy of fluorescence in situ hybridization (FISH) analysis in the differential diagnosis of adipose tissue tumors, we investigated MDM2-CDK4 status by FISH, real-time polymerase chain reaction (PCR) [quantitative PCR (Q-PCR)] and immunohistochemistry (IHC) in a series of 200 adipose tumors.
  • First, we evaluated MDM2-CDK4 amplification and expression in a series of 94 well-defined adipose tissue tumors.
  • We then used the same techniques as complementary diagnostic tools in a series of 106 adipose and soft tissue tumors of unclear diagnosis to distinguish between (i) lipomas and atypical lipomatous tumor/well-differentiated liposarcomas, (ii) malignant undifferentiated tumors and dedifferentiated liposarcomas, and (iii) a variety of benign tumors and liposarcomas.
  • When tumor cells represented a minor component of the tumor tissue, such as with inflammatory tumors, FISH was more powerful than Q-PCR by allowing visualization of individual cells.
  • In conclusion, we recommend that the evaluation of MDM2-CDK4 amplification using FISH or Q-PCR be used to supplement IHC analysis when diagnosis of adipose tissue tumors is not possible based on clinical and histologic information alone.
  • [MeSH-major] Cyclin-Dependent Kinase 4 / genetics. Immunohistochemistry / methods. In Situ Hybridization, Fluorescence / methods. Lipoma / genetics. Liposarcoma / diagnosis. Nucleic Acid Amplification Techniques. Proto-Oncogene Proteins c-mdm2 / genetics. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adipose Tissue / metabolism. Adipose Tissue / pathology. Adolescent. Adult. Aged. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Female. Gene Expression Profiling / methods. Humans. Male. Middle Aged. Paraffin Embedding. Reproducibility of Results. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 17895748.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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28. Moaath A, Raed E, Mohammad R, Mohammad S: Lipoblastoma: a rare mediastinal tumor. Ann Thorac Surg; 2009 Nov;88(5):1695-7

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  • [Title] Lipoblastoma: a rare mediastinal tumor.
  • Lipoblastoma is a rare benign mesenchymal tumor of embryonal fat that occurs almost exclusively in infants and children less than age 3.
  • It is a benign tumor with a high recurrence rate.
  • We emphasize that this rare mediastinal tumor should be included in the differential diagnosis of infants having a mediastinal mass.
  • [MeSH-major] Mediastinal Neoplasms / diagnosis. Neoplasms, Adipose Tissue / diagnosis

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  • (PMID = 19853146.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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29. Smith CS, Teruya-Feldstein J, Caravelli JF, Yeung HW: False-positive findings on 18F-FDG PET/CT: differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values. AJR Am J Roentgenol; 2008 Apr;190(4):1091-6
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  • [Title] False-positive findings on 18F-FDG PET/CT: differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values.
  • OBJECTIVE: Hibernoma is a benign tumor of brown fat that has imaging features similar to those of malignant fat-containing soft-tissue tumors.
  • CONCLUSION: Variation in standardized uptake values over time is an imaging characteristic that may be helpful for differentiating hibernoma and malignant fatty tumor.
  • [MeSH-major] Fluorodeoxyglucose F18. Neoplasms, Adipose Tissue / radiography. Neoplasms, Adipose Tissue / radionuclide imaging. Radiopharmaceuticals. Tomography, Emission-Computed. Tomography, X-Ray Computed
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. False Positive Reactions. Female. Humans. Lipoma / radiography. Lipoma / radionuclide imaging. Male. Middle Aged. Retrospective Studies

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  • (PMID = 18356460.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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30. Wang K, Wang T, Fu F, Ji ZY, Liu RG, Liao QM, Dong XZ: Electrical impedance scanning in breast tumor imaging: correlation with the growth pattern of lesion. Chin Med J (Engl); 2009 Jul 5;122(13):1501-6
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  • [Title] Electrical impedance scanning in breast tumor imaging: correlation with the growth pattern of lesion.
  • BACKGROUND: This study researched the electric impedance properties of breast tissue and demonstrated the different characteristic of electrical impedance scanning (EIS) images.
  • METHODS: The impedance character of 40 malignant tumors, 34 benign tumors and some normal breast tissue from 69 patients undergoing breast surgery was examined by EIS in vivo measurement and mammography screening, with a series of frequencies set between 100 Hz - 100 kHz in the ex vivo spectroscopy measurement.
  • Of the 30 patients with 34 benign tumors there were almost no specific abnormality shown in the EIS results.
  • Primary ex vivo spectroscopy experiments showed that the resistivity of various breast tissue take the following pattern: adipose tissue > cancerous tissue > mammary gland and benign tumor tissue.
  • CONCLUSIONS: There are significant differences in the electrical impedance properties between cancerous tissue and healthy tissue.
  • The impedivity of benign tumor is lower, and is at the same level with that of the mammary glandular tissue.

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  • (PMID = 19719937.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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31. Plaza JA, Wakely PE Jr, Suster S: Lipoblastic nerve sheath tumors: report of a distinctive variant of neural soft tissue neoplasm with adipocytic differentiation. Am J Surg Pathol; 2006 Mar;30(3):337-44
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  • [Title] Lipoblastic nerve sheath tumors: report of a distinctive variant of neural soft tissue neoplasm with adipocytic differentiation.
  • Benign nerve sheath tumors of soft tissue can occasionally adopt unusual or unfamiliar morphologic appearances that may introduce difficulties for diagnosis, such as multinucleation, bizarre nuclei, intranuclear vacuoles, and other degenerative changes.
  • Tumor cells adopting a signet-ring or lipoblast-like configuration, however, are mostly associated with epithelial malignancies, liposarcoma and melanoma, and have been only rarely observed in spindle cell tumors of soft tissue.
  • We report 5 cases of benign nerve sheath neoplasms that displayed prominent signet-ring cells with lipoblast-like features.
  • The cases presented as solitary soft tissue masses in the groin, thigh, retroperitoneum, and shoulder in 4 men and 1 woman between the ages of 31 to 57 years.
  • The presence of mature fat and signet-ring lipoblast-like cells within a nerve sheath neoplasm is quite rare and may signify a process of aberrant differentiation.
  • Neurogenic tumors should be added in the differential diagnosis of spindle cell tumors capable of displaying prominent signet-ring cell features.
  • [MeSH-major] Adipose Tissue / pathology. Nerve Sheath Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Carcinoma, Signet Ring Cell / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission. Middle Aged

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  • (PMID = 16538053.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Jung SJ, Shen SS, Tran T, Jun SY, Truong L, Ayala AG, Ro JY: Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literature. Hum Pathol; 2008 Mar;39(3):463-8
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  • [Title] Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literature.
  • We present 2 cases of mixed epithelial and stromal tumor of the kidney with sarcomatous transformation.
  • The resected tumor involved the right renal parenchyma, measuring 13.0 x 8.0 x 4.0 cm, and extended to perirenal adipose tissue.
  • The tumor measured 6.0 x 5.5 x 4.0 cm, with an intact capsule at the upper pole.
  • Sections of both tumors revealed benign and malignant components.
  • The benign component consisted of multilocular cysts and fibrous stroma with a focally ovarian stromalike component.
  • We report 2 additional cases of sarcomatous transformation in mixed epithelial and stromal tumor of the kidney.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Carcinoma / metabolism. Carcinoma / pathology. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Middle Aged. Stromal Cells / metabolism. Stromal Cells / pathology

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  • (PMID = 18261632.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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33. Demiralp B, Alderete JF, Kose O, Ozcan A, Cicek I, Basbozkurt M: Osteolipoma independent of bone tissue: a case report. Cases J; 2009;2:8711

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteolipoma independent of bone tissue: a case report.
  • INTRODUCTION: Lipomas are the most common benign soft tissue tumors and appear in any part of the body.
  • They typically consist of mature adipose tissue.
  • Osteolipoma is an extremely rare histologic variant of lipoma that contains mature lamellar bone within the tumor and osteolipoma independent of bone tissue are very rare.
  • Given the benign imaging characteristics and fine needle aspiration, an excisional biopsy was undertaken.
  • The definitive pathologic diagnosis was intramuscular osteolipoma without evidence of malignancy.
  • CONCLUSION: Although ossifying lipomas are very rare, it is important to keep them in mind when a lesion with adipose tissue in combination with ossification is encountered.

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  • [Cites] Br J Radiol. 2008 Aug;81(968):e207-10 [18628326.001]
  • [Cites] ORL J Otorhinolaryngol Relat Spec. 2000 May-Jun;62(3):170-2 [10810265.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jun;105(6):e30-4 [18417387.001]
  • [Cites] J Hand Surg Eur Vol. 2008 Feb;33(1):82-3 [18332028.001]
  • [Cites] J Craniofac Surg. 2007 Sep;18(5):1176-9 [17912108.001]
  • [Cites] J Cutan Pathol. 2007 Oct;34(10):788-92 [17880585.001]
  • [Cites] J Clin Neurosci. 2005 Aug;12(6):714-7 [16098751.001]
  • [Cites] Kulak Burun Bogaz Ihtis Derg. 2004;13(3-4):84-6 [16055988.001]
  • [Cites] Virchows Arch. 1999 Feb;434(2):181-3 [10071255.001]
  • [Cites] Skeletal Radiol. 1994 Jan;23(1):67-9 [8160042.001]
  • [Cites] AJR Am J Roentgenol. 1994 Jan;162(1):105-10 [8273646.001]
  • [Cites] J Oral Maxillofac Surg. 1992 Sep;50(9):1015-7 [1506960.001]
  • [Cites] Radiographics. 1991 Jan;11(1):81-106 [1996399.001]
  • [Cites] J Postgrad Med. 1989 Jan;35(1):54-6 [2511298.001]
  • [Cites] Pathol Res Pract. 1989 Apr;184(4):437-45 [2657678.001]
  • [Cites] Radiographics. 2004 Sep-Oct;24(5):1433-66 [15371618.001]
  • [Cites] Br J Oral Maxillofac Surg. 2004 Aug;42(4):363-4 [15225961.001]
  • [Cites] Oral Oncol. 2001 Jul;37(5):468-70 [11377236.001]
  • [Cites] Clin Experiment Ophthalmol. 2008 Jul;36(5):473-4 [18925915.001]
  • (PMID = 19918398.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769468
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34. Nilsson M, Domanski H, Mertens F, Mandahl N: Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12. Oncol Rep; 2005 Apr;13(4):649-52

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  • [Title] Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12.
  • Atypical lipomatous tumor (ALT), an intermediate malignant neoplasm of soft tissues, is characterized by the presence of supernumerary ring and giant marker chromosomes.
  • These findings are consistent with previous reports that the ALT phenotype may be associated with a low or moderate level of gene amplification, whereas truncation of HMGA2 has been observed in both ALTs and benign lipomas.
  • Whether ALTs with these types of aberrations have a lower risk of tumor progression than ALTs with the notoriously mitotically unstable ring and giant marker chromosomes remains to be investigated.
  • [MeSH-major] Chromosome Aberrations. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 8. Lipoma / genetics. Lipoma / pathology. Neoplasms, Adipose Tissue / genetics. Neoplasms, Adipose Tissue / pathology

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  • (PMID = 15756437.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
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35. Wang X, Pogue BW, Jiang S, Dehghani H, Song X, Srinivasan S, Brooksby BA, Paulsen KD, Kogel C, Poplack SP, Wells WA: Image reconstruction of effective Mie scattering parameters of breast tissue in vivo with near-infrared tomography. J Biomed Opt; 2006 Jul-Aug;11(4):041106
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Image reconstruction of effective Mie scattering parameters of breast tissue in vivo with near-infrared tomography.
  • A method for image reconstruction of the effective size and number density of scattering particles is discussed within the context of interpreting near-infrared (NIR) tomography images of breast tissue.
  • Then the method was used in NIR patient images, and it indicates that for a cancer tumor, the effective scatterer size is smaller than the background breast values and the effective number density is higher.
  • In contrast, for benign tumor patients, there is not a significant difference in effective scatterer size or number density between tumor and normal tissues.
  • The method was used to interpret magnetic resonance imaging-coupled NIR images of adipose and fibroglandular tissues, and it indicated that the fibroglandular tissue has smaller effective scatterer size and larger effective number density than the adipose tissue does.
  • [MeSH-major] Breast / pathology. Breast Neoplasms / diagnosis. Image Enhancement / methods. Image Interpretation, Computer-Assisted / methods. Infrared Rays. Refractometry / methods. Tomography, Optical / methods

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  • (PMID = 16965134.001).
  • [ISSN] 1083-3668
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01CA80139; United States / NCI NIH HHS / CA / U54CA105480
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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36. Righini ChA, Delalande C, Soriano E, Schmerber S, Passagia JG, Reyt E: [Reconstruction after tumor resection of the anterior skull base with an of abdominal fat graft]. Ann Otolaryngol Chir Cervicofac; 2005 Nov;122(5):236-45

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  • [Title] [Reconstruction after tumor resection of the anterior skull base with an of abdominal fat graft].
  • OBJECTIVES: Reconstruction of the anterior skull base is a surgical stage as significant as tumor removal.
  • 45 had a malignant tumor and 10 a benign tumor.
  • Forty-three patients treated for a malignant tumor underwent postoperative radiotherapy.
  • [MeSH-major] Adipose Tissue / transplantation. Skull Base Neoplasms / surgery

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  • (PMID = 16439934.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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37. Spinelli C, Costanzo S, Severi E, Giannotti G, Massart F: A thoracic wall lipoblastoma in a 3-month-old infant: A case report and review of the literature. J Pediatr Hematol Oncol; 2006 Sep;28(9):594-600

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  • Lipoblastoma is a rare benign tumor of adipose tissue seen almost always in infancy and early childhood.
  • Lipoblastoma is a tumor with good prognosis with no reported metastases, despite its potential for local invasion and rapid growth.
  • With the aim of both diagnosis and treatment, the lipomatous mass was removed by local resection.
  • In addition to the patient's age, histologic and cytogenetic analyses assisted the diagnosis of diffuse lipoblastoma.
  • [MeSH-major] Lipoma / genetics. Lipoma / pathology. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology. Thoracic Wall / pathology

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  • (PMID = 17006266.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Simpfendorfer CS, Ilaslan H, Davies AM, James SL, Obuchowski NA, Sundaram M: Does the presence of focal normal marrow fat signal within a tumor on MRI exclude malignancy? An analysis of 184 histologically proven tumors of the pelvic and appendicular skeleton. Skeletal Radiol; 2008 Sep;37(9):797-804
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does the presence of focal normal marrow fat signal within a tumor on MRI exclude malignancy? An analysis of 184 histologically proven tumors of the pelvic and appendicular skeleton.
  • OBJECTIVE: The aim of this study was to determine if the presence of focal normal bone marrow fat signal within a tumor on magnetic resonance imaging excludes malignancy.
  • There were 111 malignant and 73 benign tumors.
  • Two radiologists at each institution, blinded to the diagnosis, reviewed the MRIs independently and reported the presence or absence of normal marrow fat signal within the tumor based upon T1-weighted imaging without fat suppression and T2-weighted imaging with fat suppression and/or short inversion-time inversion recovery (STIR).
  • For each institution, a Fisher's exact test was used to compare the frequency of focal normal marrow fat signal in benign and malignant tumors.
  • Fisher's exact test was also used to compare the frequency of intratumoral fat in benign and malignant lesions for the pooled sample.
  • There were three discrepancies (one malignant and two benign) at site 1 and four discrepancies (two malignant and two benign) at site 2.
  • Reader consensus at site 1 identified normal marrow fat signal within 1 of 50 (2.0%) malignant and three of 14 (21.4%) benign tumors.
  • Reader consensus at site 2 identified normal marrow fat signal within three of 61 (4.9%) malignant and 14 of 59 (23.7%) benign tumors.
  • For the pooled consensus, the frequency of intratumoral fat in benign lesions (17/73, 23.3%) is significantly greater than the frequency in malignant lesions (4/111, 3.6%), p < 0.001.
  • CONCLUSION: The presence of focal normal marrow signal within a tumor is highly suggestive of a benign tumor.
  • [MeSH-major] Adipose Tissue / pathology. Bone Marrow / pathology. Bone Neoplasms / pathology. Magnetic Resonance Imaging / methods. Pelvic Bones / pathology
  • [MeSH-minor] Algorithms. Bayes Theorem. Female. Humans. Male. Neoplasm Metastasis. Predictive Value of Tests. Reproducibility of Results

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  • [Cites] AJR Am J Roentgenol. 1985 Jun;144(6):1131-5 [3873791.001]
  • [Cites] Eur Radiol. 2002 Jul;12(7):1811-8 [12111073.001]
  • [Cites] AJR Am J Roentgenol. 1985 Nov;145(5):1031-7 [3876734.001]
  • [Cites] Radiology. 2005 Nov;237(2):590-6 [16244268.001]
  • [Cites] Skeletal Radiol. 1986;15(7):511-7 [3775414.001]
  • [Cites] AJR Am J Roentgenol. 1986 Feb;146(2):353-8 [3484586.001]
  • [Cites] Skeletal Radiol. 1998 Oct;27(10):529-45 [9840389.001]
  • [Cites] Radiology. 1990 Feb;174(2):495-502 [2296658.001]
  • [Cites] AJR Am J Roentgenol. 1997 Nov;169(5):1439-47 [9353477.001]
  • [Cites] Radiology. 1989 Jun;171(3):767-73 [2717749.001]
  • [Cites] Clin Imaging. 2004 Mar-Apr;28(2):102-8 [15050221.001]
  • [Cites] J Magn Reson Imaging. 1997 Jan-Feb;7(1):241-50 [9039623.001]
  • [Cites] Skeletal Radiol. 2001 Jul;30(7):378-83 [11499777.001]
  • [Cites] AJR Am J Roentgenol. 1991 Jul;157(1):87-92 [1904679.001]
  • [Cites] Radiology. 1998 May;207 (2):349-56 [9577479.001]
  • [Cites] J Comput Assist Tomogr. 1999 Jan-Feb;23 (1):123-9 [10050822.001]
  • [Cites] Eur Radiol. 2007 Mar;17(3):743-61 [17021706.001]
  • [Cites] Radiographics. 1991 Mar;11(2):219-32 [2028061.001]
  • [Cites] Australas Radiol. 1993 Feb;37(1):35-9 [8323508.001]
  • (PMID = 18551289.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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39. Crombez KR, Vanoirbeek EM, Van de Ven WJ, Petit MM: Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2. Mol Cancer Res; 2005 Feb;3(2):63-70
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  • [Title] Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2.
  • The gene encoding the architectural transcription factor HMGA2 is frequently rearranged in several benign tumors of mesenchymal origin.
  • The lipoma preferred partner (LPP) gene is the most frequent translocation partner of HMGA2 in a subgroup of lipomas, which are benign tumors of adipose tissue.
  • Identical fusion transcripts are also expressed in other benign mesenchymal tumors.
  • [MeSH-minor] Amino Acid Motifs. Cells, Cultured. Cytoskeletal Proteins / genetics. Cytoskeletal Proteins / physiology. Gene Expression Regulation, Neoplastic. Humans. LIM Domain Proteins. Neoplasm Proteins / genetics. Neoplasm Proteins / physiology. Promoter Regions, Genetic / genetics. Protein Structure, Tertiary. Rhodopsin / genetics. Transcription, Genetic

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  • (PMID = 15755872.001).
  • [ISSN] 1541-7786
  • [Journal-full-title] Molecular cancer research : MCR
  • [ISO-abbreviation] Mol. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cytoskeletal Proteins; 0 / HMGA Proteins; 0 / HMGA2 Protein; 0 / HMGA2-LPP fusion protein, human; 0 / LIM Domain Proteins; 0 / LPP protein, human; 0 / Neoplasm Proteins; 0 / Oncogene Proteins, Fusion; 9009-81-8 / Rhodopsin
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40. Shaco-Levy R, Piura B: Uterine adenolipoleiomyoma: a tumor with potential of aggressive behavior. Int J Gynecol Pathol; 2008 Apr;27(2):252-7
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  • [Title] Uterine adenolipoleiomyoma: a tumor with potential of aggressive behavior.
  • Histology showed the mass to be composed of benign-appearing smooth muscle, mature adipose tissue, and bland endocervical-type glands.
  • The recurrent adenolipoleiomyoma contained, in addition, benign-appearing endometrial-type glands and stroma and showed small foci of atypically proliferating endocervical-type epithelium.
  • [MeSH-minor] Female. Humans. Neoplasm Invasiveness. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Uterus / pathology

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  • (PMID = 18317215.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Binh MB, Sastre-Garau X, Guillou L, de Pinieux G, Terrier P, Lagacé R, Aurias A, Hostein I, Coindre JM: MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol; 2005 Oct;29(10):1340-7
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  • [Title] MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data.
  • Atypical lipomatous tumor/well-differentiated liposarcoma (ALT-WDLPS) and dedifferentiated liposarcoma (DDLPS) may be difficult to distinguish from benign adipose tumors and from poorly differentiated sarcomas, respectively.
  • We examined a series of 559 soft tissue tumors (44 ALT-WDLPS, 61 DDLPS, 49 benign adipose tumors, and 405 non-ALT-WDLPS/DDLPS sarcomas) for MDM2 and CDK4 expression using immunohistochemistry.
  • Most ALT-WDLPS/DDLPS expressed MDM2 (97%) and CDK4 (92%) as opposed to few benign adipose tumors (MDM2, 5%; CDK4, 2%) and a limited number of non-ALT-WDLSP/DDLPS sarcomas (MDM2, 19%; CDK4, 6%).
  • The sensitivity and specificity of MDM2 and CDK4 immunostainings in identifying ALT-WDLPS/DDLPS among other soft tissue tumors were 97% and 92%, and 83% and 95%, respectively.
  • MDM2 and CDK4 immunostainings were particularly useful to separate ALT-WDLPS from the large group of differentiated adipose tumors, and to distinguish DDLPS from poorly differentiated sarcomas.
  • In conclusion, MDM2 and CDK4 immunostainings, which correlate with gene amplification, are helpful adjuncts to differentiate ALT-WDLPS from benign adipose tumors and to separate DDLPS from poorly differentiated sarcomas.
  • [MeSH-major] Cyclin-Dependent Kinase 4 / metabolism. Liposarcoma / diagnosis. Proto-Oncogene Proteins c-mdm2 / metabolism. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Gene Amplification. Humans. Immunohistochemistry. Male. Middle Aged. Polymerase Chain Reaction. Sensitivity and Specificity

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  • (PMID = 16160477.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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42. Kennedy S, Geradts J, Bydlon T, Brown JQ, Gallagher J, Junker M, Barry W, Ramanujam N, Wilke L: Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. Breast Cancer Res; 2010;12(6):R91
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  • [Title] Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast.
  • Breast tissue is markedly heterogeneous, which makes distinguishing small foci of cancer within the spectrum of normal tissue potentially challenging.
  • Here, we evaluate ex-vivo breast tissue and determine which sources of optical contrast have the potential to detect malignancy at the margins in women of differing breast composition.
  • Normal and malignant sites were compared before stratifying the data by tissue type and depth and computing statistical differences.
  • The frequencies of the normal tissue types were separated by menopausal status and compared to the corresponding optical properties.
  • The sites stratified according to normal tissue type (fibro-glandular (FG), fibro-adipose (FA), and adipose (A)) or disease type (invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS)) showed that FG exhibited increased < μs' > and A showed increased [β-carotene] within normal tissues.
  • The diagnostic ability of the optical parameters was affected by distance of tumor from the margin as well as menopausal status.
  • Due to decreased fibrous content and increased adipose content, normal sites in post-menopausal patients exhibited lower < μs' >, but higher [β-carotene] than pre-menopausal patients.
  • CONCLUSIONS: The data indicate that the ability of an optical parameter to differentiate benign from malignant breast tissues may be dictated by patient demographics.
  • Scattering differentiated between malignant and adipose sites and would be most effective in post-menopausal women.

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  • [Cites] Lasers Surg Med. 2010 Jan;42(1):15-23 [20077490.001]
  • [Cites] J Surg Res. 2010 May 15;160(2):277-81 [19628225.001]
  • [Cites] Blood. 2010 May 20;115(20):4111-9 [20107229.001]
  • [Cites] Opt Express. 2010 Apr 12;18(8):8058-76 [20588651.001]
  • [Cites] Cancer Res. 2009 Nov 15;69(22):8790-6 [19910294.001]
  • [Cites] Neoplasia. 2000 Jan-Apr;2(1-2):26-40 [10933066.001]
  • [Cites] J Biomed Opt. 2000 Apr;5(2):221-8 [10938787.001]
  • [Cites] Photochem Photobiol. 2000 Sep;72(3):383-91 [10989610.001]
  • [Cites] Acad Radiol. 2001 Mar;8(3):211-8 [11249084.001]
  • [Cites] Am J Surg. 2002 Nov;184(5):383-93 [12433599.001]
  • [Cites] J Biomed Opt. 2003 Apr;8(2):223-36 [12683848.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12349-54 [14514888.001]
  • [Cites] J Biomed Opt. 2004 Jan-Feb;9(1):230-8 [14715078.001]
  • [Cites] J Biomed Opt. 2004 May-Jun;9(3):541-52 [15189092.001]
  • [Cites] Arch Surg. 1991 Apr;126(4):490-3 [2009065.001]
  • [Cites] Cancer J Sci Am. 1997 Sep-Oct;3(5):273-7 [9327150.001]
  • [Cites] Am Surg. 2005 Jan;71(1):22-7; discussion 27-8 [15757052.001]
  • [Cites] J Am Coll Surg. 2005 Aug;201(2):194-8 [16038815.001]
  • [Cites] J Am Coll Surg. 2005 Dec;201(6):855-61 [16310688.001]
  • [Cites] Lancet. 2005 Dec 17;366(9503):2087-106 [16360786.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1062-71 [16512550.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1072-8 [16512551.001]
  • [Cites] Technol Cancer Res Treat. 2006 Aug;5(4):301-9 [16866560.001]
  • [Cites] Lasers Surg Med. 2006 Aug;38(7):714-24 [16799981.001]
  • [Cites] Ann Surg Oncol. 2007 Mar;14(3):1045-50 [17206481.001]
  • [Cites] Ann Surg Oncol. 2007 Apr;14(4):1458-71 [17260108.001]
  • [Cites] Am J Surg. 2007 Oct;194(4):467-73 [17826057.001]
  • [Cites] Ann Surg Oncol. 2007 Sep;14(9):2425-7 [17597344.001]
  • [Cites] Ann Surg Oncol. 2007 Oct;14(10):2953-60 [17674109.001]
  • [Cites] Ann Surg Oncol. 2008 May;15(5):1297-303 [18259820.001]
  • [Cites] Ann Surg Oncol. 2008 May;15(5):1271-2 [18320287.001]
  • [Cites] J Biomed Opt. 2008 Mar-Apr;13(2):024012 [18465975.001]
  • [Cites] J Am Coll Surg. 2008 Jun;206(3):1116-21 [18501808.001]
  • [Cites] J Biomed Opt. 2008 May-Jun;13(3):034015 [18601560.001]
  • [Cites] Am J Surg. 2008 Oct;196(4):483-9 [18809049.001]
  • [Cites] Breast J. 2009 Jan-Feb;15(1):34-40 [19141132.001]
  • [Cites] J Clin Oncol. 2009 Apr 1;27(10):1615-20 [19255332.001]
  • [Cites] Cancer Res. 2009 Apr 1;69(7):2919-26 [19293184.001]
  • [Cites] Curr Opin Biotechnol. 2009 Feb;20(1):119-31 [19268567.001]
  • [Cites] Ann Surg Oncol. 2009 Oct;16(10):2717-30 [19609829.001]
  • [Cites] Am J Surg. 2009 Oct;198(4):566-74 [19800470.001]
  • [Cites] JAMA. 2009 Oct 14;302(14):1551-6 [19826024.001]
  • [Cites] J Biomed Opt. 2009 Sep-Oct;14(5):054023 [19895125.001]
  • (PMID = 21054873.001).
  • [ISSN] 1465-542X
  • [Journal-full-title] Breast cancer research : BCR
  • [ISO-abbreviation] Breast Cancer Res.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 1R41CA128160-01; United States / NCRR NIH HHS / RR / 1UL1 RR024128-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemoglobins; 01YAE03M7J / beta Carotene
  • [Other-IDs] NLM/ PMC3046432
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43. Yalniz E, Alicioglu B, Oz Puyan F: Hibernoma: a benign lipomatous tumor mimicking liposarcoma. J BUON; 2008 Jan-Mar;13(1):127-9
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  • [Title] Hibernoma: a benign lipomatous tumor mimicking liposarcoma.
  • Hibernoma is a rare, benign, slow-growing soft tissue tumor.
  • Due to its rich vascularity and magnetic resonance appearance, this tumor may mimic a liposarcoma before tissue diagnosis.
  • The clinical presentation, radiographic and histopathologic features of this rare benign soft tissue tumor are presented.
  • This tumor is clinically important because it is indistinguishable from malignant lesions.
  • [MeSH-major] Lipoma / pathology. Liposarcoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 18404800.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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44. Cao D, Srodon M, Montgomery EA, Kurman RJ: Lipomatous variant of angiomyofibroblastoma: report of two cases and review of the literature. Int J Gynecol Pathol; 2005 Apr;24(2):196-200
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  • [Title] Lipomatous variant of angiomyofibroblastoma: report of two cases and review of the literature.
  • Angiomyofibroblastoma (AMF) is a rare, benign, mesenchymal tumor occurring mainly in the female genital tract.
  • Some cases contain scattered mature adipocytes, but the lipomatous variant in which mature adipose tissue is prominent or striking is rare.
  • We report two more such cases that were composed of 70 to 80% and 30 to 40% adipose tissue, respectively.
  • Immunohistochemical analysis showed that the tumor cells were positive for estrogen receptor, progesterone receptor, vimentin, and Bcl-2, and negative for cytokeratin AE1/1, EMA, and CD117.
  • Tumor cells in the first case were positive for CD34 but not desmin and muscle-specific actin.
  • The opposite expression profile of these three markers was observed in tumor cells in the second case: positive for desmin and muscle-specific actin and negative for CD34.
  • Rare cells were positive for S-100 in adipose-rich areas in the first case.
  • Our findings indicate that the tumor cells in the lipomatous variant have similar immunoprofile to those of usual AMF and support the concept that the lipomatous variant probably represents an extreme end of a wide spectrum of differentiation in AMF.
  • [MeSH-minor] Adipose Tissue / metabolism. Adipose Tissue / pathology. Adult. Biomarkers, Tumor. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Myxoma / pathology

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  • (PMID = 15782077.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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45. Siddaraju N, Singh N, Muniraj F, Jothilingam P, Kumar S, Basu D, Saxena SK: Preoperative cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia: a case report. Acta Cytol; 2009 Jul-Aug;53(4):457-9
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  • BACKGROUND: Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin.
  • Fine needle aspiration yielded sticky, fatty material; the smears showed features of pleomorphic adenoma with intimately associated, abundant adipose tissue elements.
  • CONCLUSION: Pleomorphic adenoma with extensive lipometaplasia is an unusual benign salivary gland tumor with distinct histomorphology.
  • Cytologically, it is characterized by the presence of an excessive amount of intimately associated adipose tissue in an otherwise-classic pleomorphic adenoma.
  • [MeSH-minor] Adipose Tissue / pathology. Biopsy, Fine-Needle. Humans. Male. Metaplasia / pathology. Middle Aged

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  • (PMID = 19697737.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Kazakov DV, Hes O, Hora M, Sima R, Michal M: Primary intranodal cellular angiolipoma. Int J Surg Pathol; 2005 Jan;13(1):99-101

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiolipoma is a distinct, benign soft tissue tumor that most commonly occurs in young males as multiple small, subcutaneous, tender to painful nodules with predilection for the forearms.
  • Microscopically, the major portion of the lymph node was replaced by mature metaplastic adipose tissue.
  • The most recognized examples are pigmented nevi, palisading myofibroblastoma, various benign epithelial inclusions, serous cystic tumors of borderline malignancy, and hyperplastic mesothelial inclusions.
  • As we present in this report, angiolipoma is another neoplasm whose primary occurrence in the lymph node should not be misinterpreted as a metastatic tumor or malignant vascular tumor.
  • [MeSH-major] Angiolipoma / pathology. Lymph Nodes / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adipose Tissue / pathology. Aged. Antigens, CD31 / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Lymphatic Metastasis / diagnosis. Male. Metaplasia / pathology

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  • (PMID = 15735863.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor
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47. Kern MA, Kasper HU, Drebber U, Guntinas-Lichius O, Veelken F, Ortmann M: [Report of a spindle cell myoepithelialioma of the minor salivary glands with extensive lipomatous component]. Laryngorhinootologie; 2005 Jun;84(6):432-5
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  • [Title] [Report of a spindle cell myoepithelialioma of the minor salivary glands with extensive lipomatous component].
  • Myoepitheliomas of the salivary glands are rare benign tumors composed of spindle-shaped myoepithelial cells, but may show plasmacytoid, epitheloid and clear cell-types that principally exhibit myoepithelial but not ductal differentiation.
  • Lipomatosis in the form of isolated small islands or scattered single lipocytes, is quite uncommon, and a large amount of adipose tissue in a pleomorphic adenoma and myoepithelioma is a rarity and only described in major salivary glands.
  • [MeSH-minor] Adipose Tissue / pathology. Adult. Biomarkers, Tumor / analysis. Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Male

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  • (PMID = 15940575.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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48. Al-Momani HM: Recurrent maturing perineal lipoblastoma. Saudi Med J; 2005 Nov;26(11):1815-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma is a rare benign neoplasm of fetal adipose tissue that we see mostly in infants and young children less than 3 years of age.
  • We report a case of a recurrent perineal lipoblastoma in a 2.5-year-old boy, which showed maturation of the lipoblasts as compared to the primary tumor.
  • [MeSH-major] Lipoma / pathology. Lipoma / surgery. Neoplasms, Adipose Tissue / pathology. Neoplasms, Adipose Tissue / surgery

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  • (PMID = 16311674.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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49. Kourda J, Ayadi-Kaddour A, Merai S, Hantous S, Miled KB, Mezni FE: Bilateral elastofibroma dorsi. A case report and review of the literature. Orthop Traumatol Surg Res; 2009 Sep;95(5):383-7
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for elastofibroma dorsi .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Elastofibroma is a rare benign soft tissue lesion, typically located deep under the lower pole of the scapula.
  • It is characterized by a fibrous and adipose tissue proliferation and most frequently affects older females.
  • Its characteristic location and its specific aspect in imaging studies most often provides the diagnosis following an incidental discovery.
  • Nevertheless, anatomic and pathologic confirmation is necessary to formally rule out a malignant tumor diagnosis.
  • MRI demonstrated, in fact, two symmetrical tumor masses under each scapula.
  • [MeSH-major] Elastic Tissue. Fibroma / diagnosis. Scapula. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Ultrasonography

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  • [Copyright] 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 19628444.001).
  • [ISSN] 1877-0568
  • [Journal-full-title] Orthopaedics & traumatology, surgery & research : OTSR
  • [ISO-abbreviation] Orthop Traumatol Surg Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 21
  • [General-notes] NLM/ Original DateCompleted: 20091028
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50. Ito R, Fujiwara M, Takagaki K, Nagasako R: Chondrolipoma of the toe. J Dermatol; 2007 Aug;34(8):570-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondrolipoma is a rare benign mesenchymoma composed of mature cartilage and adipose tissue.
  • On histological examination, the tumor contained both mature fat cells and chondrocytes.
  • [MeSH-major] Foot Diseases / diagnosis. Mesenchymoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Aged. Cartilage / pathology. Humans. Magnetic Resonance Imaging. Male. S100 Proteins / analysis. Toes / pathology. Toes / radiography

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  • (PMID = 17683390.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / S100 Proteins
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51. Doğan S, Can IH, Unlü I, Süngü N, Gönültaş MA, Samim EE: Sialolipoma of the parotid gland. J Craniofac Surg; 2009 May;20(3):847-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 33-year-old male patient with a slow-growing, painless, well-circumscribed soft tissue mass on the left parotid region is presented.
  • The clinical impression was that of a benign salivary gland tumor.
  • The tumor was situated in the superficial lobe of the gland, and a superficial parotidectomy was performed, with preservation of the facial nerve.
  • Histopathologic examination results revealed a sialolipoma of the parotid gland and a lesion that consisted of both mature adipose tissue and glandular elements.
  • Preoperative diagnosis is generally difficult, and computed tomographic scanning is useful in defining these benign parotid gland masses.
  • [MeSH-major] Lipoma / diagnosis. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Adult. Diagnosis, Differential. Humans. Male. Parotid Gland / pathology

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  • (PMID = 19390452.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Craig WD, Fanburg-Smith JC, Henry LR, Guerrero R, Barton JH: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics; 2009 Jan-Feb;29(1):261-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Retroperitoneal lesions represent a broad, diverse collection of entities; when they contain fat, the differential diagnosis, which ranges from benign to fully malignant lesions, substantially narrows.
  • Hibernoma is a rare benign soft-tissue tumor composed of brown fat.
  • Teratomas are neoplasms that originate in pluripotent cells--benign or malignant germ cells--that give rise to a wide spectrum of mature or immature tissues that are foreign to the location in which they arise and which demonstrate varying amounts of organ formation.
  • Myelolipoma, a benign tumor composed of mature fat and interspersed hematopoietic elements that resemble bone marrow, typically originate in an otherwise normal adrenal gland.
  • Angiomyolipoma is composed of varying admixtures of blood vessels, smooth muscle cells, and adipose tissue; any one or two of these elements may predominate.
  • [MeSH-major] Intra-Abdominal Fat / pathology. Intra-Abdominal Fat / radiography. Lipomatosis / diagnosis. Lipomatosis / pathology. Neoplasms, Adipose Tissue / diagnosis. Neoplasms, Adipose Tissue / pathology. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Neoplasms / pathology

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  • (PMID = 19168848.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Kim HK, Choi YH, Cho YH, Sohn YS, Kim HJ: Intercostal neuralgia caused by a parosteal lipoma of the rib. Ann Thorac Surg; 2006 May;81(5):1901-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Parosteal lipoma is an extremely rare benign tumor that is composed mainly of mature adipose tissue, and it has an intimate relationship to the underlying periosteal bone.
  • Although parosteal lipoma is asymptomatic, motor and sensory function deficits have been reported that were caused by the tumor compressing the neuromuscular bundles in the proximal forearm and the sciatic nerve.
  • [MeSH-minor] Adipose Tissue / pathology. Female. Humans. Middle Aged. Neuralgia / etiology. Tomography, X-Ray Computed

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  • (PMID = 16631705.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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54. Cha JM, Lee JI, Joo KR, Choe JW, Jung SW, Shin HP, Kim HC, Lee SH, Lim SJ: Giant mesenteric lipoma as an unusual cause of abdominal pain: a case report and a review of the literature. J Korean Med Sci; 2009 Apr;24(2):333-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The resected ileal segment was encased by a giant fatty tissue, and normal mucosal fold patterns of the resected ileum were effaced by the mass.
  • Microscopically, the mass was characterized by homogenous mature adipose tissue without cellular atypia, which was compatible with the diagnosis of a mesenteric lipoma.
  • Despite the benign nature of this tumor, total excision with or without the affected intestinal loop should be considered if intestinal symptoms such as abdominal pain are present.
  • [MeSH-major] Abdominal Pain / etiology. Lipoma / diagnosis. Mesentery. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Adult. Diagnosis, Differential. Female. Humans. Ileal Diseases / etiology. Laparoscopy. Tomography, X-Ray Computed

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  • [Cites] Surg Today. 2003;33(8):617-9 [12884101.001]
  • [Cites] Pediatr Radiol. 2003 Jan;33(1):34-6 [12497235.001]
  • [Cites] AJR Am J Roentgenol. 2004 Oct;183(4):933-43 [15385284.001]
  • [Cites] Radiology. 1968 Mar;90(3):558-64 [5642294.001]
  • [Cites] Am Surg. 1976 Aug;42(8):595-7 [942124.001]
  • [Cites] Am J Proctol Gastroenterol Colon Rectal Surg. 1981 Nov;32(11):19-22 [7340516.001]
  • [Cites] J Urol. 1988 May;139(5):998-1001 [3361678.001]
  • [Cites] Br J Clin Pract. 1987 Oct;41(10):977-8 [3505181.001]
  • [Cites] Indian Pediatr. 1988 Oct;25(10):1007-9 [3248860.001]
  • [Cites] Pediatr Radiol. 1990;20(8):571-4 [2250998.001]
  • [Cites] J Urol. 1991 Aug;146(2):267-73 [1856914.001]
  • [Cites] Dis Colon Rectum. 1998 Jan;41(1):122-3 [9510325.001]
  • [Cites] Acta Radiol. 1998 Nov;39(6):695-7 [9817045.001]
  • [Cites] J Pediatr Surg. 1999 Apr;34(4):639-40 [10235343.001]
  • [Cites] Radiographics. 2005 Jan-Feb;25(1):69-85 [15653588.001]
  • [Cites] Pediatr Surg Int. 2004 Dec;20(11-12):869-71 [15205895.001]
  • [Cites] Kaohsiung J Med Sci. 2005 Mar;21(3):138-41 [15880878.001]
  • [Cites] Arch Surg. 2006 Oct;141(10):1046 [17043285.001]
  • [Cites] Surg Today. 2006;36(11):1007-11 [17072725.001]
  • [Cites] Ir J Med Sci. 2006 Oct-Dec;175(4):79-80 [17312837.001]
  • [Cites] J Ultrasound Med. 2002 Apr;21(4):473-6 [11934105.001]
  • [Cites] Eur Radiol. 2002 Apr;12(4):793-5 [11960228.001]
  • [Cites] Surg Today. 2004;34(5):470-2 [15108093.001]
  • (PMID = 19399281.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 23
  • [Other-IDs] NLM/ PMC2672139
  • [Keywords] NOTNLM ; Abdominal Pain / Computed Tomography / Laparoscopy / Lipoma / Mesentery
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55. Amin SA, Huang CC, Reierstad S, Lin Z, Arbieva Z, Wiley E, Saborian H, Haynes B, Cotterill H, Dowsett M, Bulun SE: Paracrine-stimulated gene expression profile favors estradiol production in breast tumors. Mol Cell Endocrinol; 2006 Jul 11;253(1-2):44-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Paracrine interactions between adipose fibroblasts and malignant epithelial cells are essential for structural and hormonal support of breast tumors.
  • Here, we characterized the gene expression profile of breast adipose fibroblasts in an in vitro model of malignancy to identify other paracrine interactions that support tumor growth.
  • Primary breast adipose fibroblasts from cancer-free women were treated with conditioned media from malignant breast epithelial cells or normal breast epithelial cells, and differences in gene expression were identified by microarray.
  • Immunoreactive AKR1C3 was detected in epithelial and stromal components of benign lesions and ductal carcinomas in situ, and in 59.8% of epithelial and 69.6% of stromal cells in invasive breast carcinomas.
  • AKR1C3 expression was significantly higher in myoepithelial cells surrounding the neoplastic epithelium of ductal carcinoma in situ compared with those surrounding benign epithelial lesions.
  • Malignant epithelial cell-conditioned medium significantly increased formation of testosterone and estradiol from androstenedione in breast adipose fibroblasts.
  • [MeSH-minor] 3-Hydroxysteroid Dehydrogenases / genetics. 3-Hydroxysteroid Dehydrogenases / metabolism. Adipose Tissue / cytology. Adolescent. Adult. Aromatase / genetics. Aromatase / metabolism. Cell Line, Tumor. Cells, Cultured. Culture Media, Conditioned / pharmacology. Female. Humans. Hydroxyprostaglandin Dehydrogenases / genetics. Hydroxyprostaglandin Dehydrogenases / metabolism. Immunohistochemistry. Middle Aged. Polymerase Chain Reaction. RNA, Messenger / biosynthesis

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  • (PMID = 16735089.001).
  • [ISSN] 0303-7207
  • [Journal-full-title] Molecular and cellular endocrinology
  • [ISO-abbreviation] Mol. Cell. Endocrinol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA67167
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Culture Media, Conditioned; 0 / RNA, Messenger; 4TI98Z838E / Estradiol; EC 1.1.- / 3-Hydroxysteroid Dehydrogenases; EC 1.1.1.- / AKR1C3 protein, human; EC 1.1.1.- / Hydroxyprostaglandin Dehydrogenases; EC 1.14.14.1 / Aromatase
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56. Wang SN, Tsai KB, Lee KT: Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review. J Clin Pathol; 2006 Nov;59(11):1196-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hepatic angiomyolipoma (AML), a rare benign mesenchymal tumour, is characterised by the presence of mature adipose tissue, smooth-muscle cells and thick-walled blood vessels.
  • However, the proportion of fatty tissue in these tumours is highly variable.
  • Microscopically, the amount of fat was too low to establish a diagnosis of hepatic AML.
  • However, positive homatropine methylbromide 45 immunoreactivity of the smooth-muscle cells seemed to assist in arriving at the diagnosis.
  • [MeSH-major] Adipose Tissue / pathology. Angiomyolipoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Humans. Male. Tomography, X-Ray Computed. Tropanes / analysis

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  • [Cites] Ultrastruct Pathol. 2001 Jan-Feb;25(1):21-9 [11297316.001]
  • [Cites] Eur Radiol. 2001;11(8):1389-95 [11519547.001]
  • [Cites] Asian J Surg. 2002 Jul;25(3):251-4 [12376226.001]
  • [Cites] World J Gastroenterol. 2003 Aug;9(8):1856-8 [12918138.001]
  • [Cites] Am J Surg Pathol. 1984 Oct;8(10):745-50 [6496843.001]
  • [Cites] Am J Pathol. 1986 May;123(2):195-203 [3518473.001]
  • [Cites] Pathol Res Pract. 2005;200(11-12):851-6 [15792132.001]
  • [Cites] Mod Pathol. 1994 Oct;7(8):842-5 [7838838.001]
  • [Cites] Arch Pathol Lab Med. 1996 Jan;120(1):68-72 [8554448.001]
  • [Cites] Histopathology. 1998 Jul;33(1):20-7 [9726044.001]
  • [Cites] Abdom Imaging. 1998 Sep-Oct;23(5):520-6 [9841067.001]
  • [Cites] Am J Surg Pathol. 1999 Jan;23(1):34-48 [9888702.001]
  • [Cites] Kurume Med J. 1999;46(2):127-31 [10410534.001]
  • [Cites] Pathology. 1994 Jul;26(3):230-6 [7991275.001]
  • (PMID = 17071805.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tropanes; 68JRS2HC1C / homatropine methylbromide
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC1860516
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57. Tsochatzis EA, Papatheodoridis GV, Archimandritis AJ: Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy. Mediators Inflamm; 2009;2009:831670
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy.
  • Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and can vary from benign steatosis to end-stage liver disease.
  • There is mounting evidence that cytokines secreted from adipose tissue, namely, adipokines, are implicated in the pathogenesis and progression of NAFLD.
  • In the current review, we explore the role of these adipokines, particularly leptin, adiponectin, resistin, tumor necrosis factor-a, and interleukin-6 in NASH, as elucidated in experimental models and clinical practice.
  • [MeSH-minor] Adiponectin / physiology. Humans. Interleukin-6 / physiology. Leptin / physiology. Resistin / physiology. Tumor Necrosis Factor-alpha / antagonists & inhibitors. Tumor Necrosis Factor-alpha / physiology

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  • [Cites] Gut. 2006 Mar;55(3):415-24 [16174657.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Mar;91(3):1081-6 [16394091.001]
  • [Cites] Hepatology. 2006 Mar;43(3):474-84 [16496306.001]
  • [Cites] Cytokine. 2006 Mar 7;33(5):252-7 [16564703.001]
  • [Cites] J Hepatol. 2006 Jun;44(6):1167-74 [16618517.001]
  • [Cites] J Hepatol. 2006 Jul;45(1):20-7 [16600417.001]
  • [Cites] N Engl J Med. 2006 Jun 15;354(24):2552-63 [16775236.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Sep;4(9):1154-61 [16904946.001]
  • [Cites] Hepatology. 2006 Oct;44(4):865-73 [17006923.001]
  • [Cites] Am J Gastroenterol. 2006 Nov;101(11):2629-40 [16952281.001]
  • [Cites] N Engl J Med. 2006 Nov 30;355(22):2297-307 [17135584.001]
  • [Cites] Am J Pathol. 2006 Dec;169(6):2042-53 [17148667.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2007 Apr;19(4):281-7 [17353691.001]
  • [Cites] J Gastroenterol Hepatol. 2007 May;22(5):634-8 [17444848.001]
  • [Cites] J Clin Endocrinol Metab. 2007 May;92(5):1971-4 [17341558.001]
  • [Cites] J Hepatol. 2007 Jun;46(6):1104-10 [17395331.001]
  • [Cites] Obes Surg. 2007 Apr;17(4):493-503 [17608262.001]
  • [Cites] Cell Metab. 2007 Jul;6(1):79-87 [17618858.001]
  • [Cites] J Clin Endocrinol Metab. 2007 Jul;92(7):2590-7 [17595259.001]
  • [Cites] Hepatology. 2007 Aug;46(2):582-9 [17661414.001]
  • [Cites] Am J Gastroenterol. 2007 Sep;102(9):1931-8 [17511754.001]
  • [Cites] J Hepatol. 2007 Oct;47(4):556-64 [17459514.001]
  • [Cites] Aliment Pharmacol Ther. 2008 Jan 1;27(1):80-9 [17919273.001]
  • [Cites] Aliment Pharmacol Ther. 2008 Mar 1;27(5):412-21 [18081738.001]
  • [Cites] Inflammation. 2008 Apr;31(2):91-8 [18066656.001]
  • [Cites] Clin Endocrinol (Oxf). 2008 Apr;68(4):555-60 [17941908.001]
  • [Cites] Lancet. 2008 Mar 22;371(9617):987-97 [18358926.001]
  • [Cites] Hepatology. 2008 Apr;47(4):1167-77 [18311774.001]
  • [Cites] Am J Gastroenterol. 2008 Jun;103(6):1372-9 [18510618.001]
  • [Cites] Hepatology. 2008 Aug;48(2):458-73 [18666257.001]
  • [Cites] Scand J Gastroenterol. 2008;43(9):1128-36 [18609175.001]
  • [Cites] Obes Surg. 2008 Nov;18(11):1430-7 [18500507.001]
  • [Cites] J Gastroenterol. 2008;43(11):811-22 [19012034.001]
  • [Cites] Scand J Gastroenterol. 2009;44(1):6-14 [18661429.001]
  • [Cites] Science. 1993 Jan 1;259(5091):87-91 [7678183.001]
  • [Cites] Nature. 1994 Dec 1;372(6505):425-32 [7984236.001]
  • [Cites] Science. 1996 Nov 22;274(5291):1379-83 [8910279.001]
  • [Cites] Recent Prog Horm Res. 1997;52:359-85; discussion 385-7 [9238859.001]
  • [Cites] FASEB J. 1997 Sep;11(11):851-7 [9285483.001]
  • [Cites] J Biol Chem. 1997 Nov 7;272(45):28191-3 [9353266.001]
  • [Cites] Gastroenterology. 1998 Apr;114(4):842-5 [9547102.001]
  • [Cites] Ann Intern Med. 1999 Apr 20;130(8):671-80 [10215564.001]
  • [Cites] Hepatology. 2004 Dec;40(6):1387-95 [15565570.001]
  • [Cites] Am J Gastroenterol. 2004 Dec;99(12):2365-8 [15571584.001]
  • [Cites] J Hepatol. 2004 Dec;41(6):943-9 [15582127.001]
  • [Cites] Gut. 2005 Jan;54(1):117-21 [15591515.001]
  • [Cites] Science. 2005 Jan 21;307(5708):426-30 [15604363.001]
  • [Cites] Mol Cell Biol. 2005 Feb;25(4):1569-75 [15684405.001]
  • [Cites] J Immunol. 2005 May 1;174(9):5789-95 [15843582.001]
  • [Cites] J Hepatol. 2005 Jun;42(6):928-40 [15885365.001]
  • [Cites] J Clin Endocrinol Metab. 2005 Jun;90(6):3498-504 [15797948.001]
  • [Cites] Gastroenterology. 2005 Jul;129(1):113-21 [16012941.001]
  • [Cites] Nature. 2005 Jul 21;436(7049):356-62 [16034410.001]
  • [Cites] Biochem Biophys Res Commun. 2005 Sep 9;334(4):1092-101 [16039994.001]
  • [Cites] Hepatology. 2005 Sep;42(3):568-77 [16108051.001]
  • [Cites] Hepatology. 2005 Sep;42(3):530-2 [16116627.001]
  • [Cites] FEBS Lett. 2005 Sep 12;579(22):5049-54 [16137686.001]
  • [Cites] Cell Mol Immunol. 2004 Jun;1(3):205-11 [16219169.001]
  • [Cites] Hepatology. 2005 Nov;42(5):1175-83 [16231364.001]
  • [Cites] Hepatology. 2005 Nov;42(5):987-1000 [16250043.001]
  • [Cites] Am J Gastroenterol. 2005 Dec;100(12):2717-23 [16393225.001]
  • [Cites] Liver Int. 2006 Feb;26(1):39-45 [16420507.001]
  • [Cites] Hepatology. 2006 Feb;43(2 Suppl 1):S99-S112 [16447287.001]
  • [Cites] Am J Clin Nutr. 2006 Feb;83(2):461S-465S [16470013.001]
  • [Cites] J Gastroenterol Hepatol. 2009 Feb;24(2):233-7 [18713296.001]
  • [Cites] Obes Surg. 2009 Apr;19(4):467-74 [18923878.001]
  • [Cites] Dig Dis Sci. 2009 Aug;54(8):1772-7 [19005759.001]
  • [Cites] Ann Intern Med. 2000 Jan 18;132(2):112-7 [10644271.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8536-41 [10900012.001]
  • [Cites] Am J Gastroenterol. 2000 Dec;95(12):3584-9 [11151896.001]
  • [Cites] Hepatology. 2001 Aug;34(2):288-97 [11481614.001]
  • [Cites] Annu Rev Med. 2002;53:319-36 [11818477.001]
  • [Cites] Gastroenterology. 2002 Feb;122(2):274-80 [11832442.001]
  • [Cites] Hepatology. 2002 Apr;35(4):762-71 [11915021.001]
  • [Cites] N Engl J Med. 2002 Apr 18;346(16):1221-31 [11961152.001]
  • [Cites] Gastroenterology. 2002 May;122(5):1399-410 [11984526.001]
  • [Cites] Gastroenterology. 2002 May;122(5):1529-32 [11984539.001]
  • [Cites] Hepatology. 2002 Aug;36(2):403-9 [12143049.001]
  • [Cites] Biochem Biophys Res Commun. 2003 Jan 10;300(2):472-6 [12504108.001]
  • [Cites] J Clin Invest. 2003 Jan;111(2):225-30 [12531878.001]
  • [Cites] Hepatology. 2003 Feb;37(2):343-50 [12540784.001]
  • [Cites] Med Sci Monit. 2003 Feb;9(2):RA55-61 [12601307.001]
  • [Cites] J Biol Chem. 2003 Mar 14;278(11):9073-85 [12496257.001]
  • [Cites] Hepatology. 2003 Apr;37(4):917-23 [12668987.001]
  • [Cites] J Clin Invest. 2003 Jul;112(1):91-100 [12840063.001]
  • [Cites] Hepatology. 2003 Sep;38(3):674-82 [12939594.001]
  • [Cites] J Biol Chem. 2003 Nov 14;278(46):45209-15 [12944409.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14217-22 [14617771.001]
  • [Cites] J Clin Invest. 2003 Dec;112(12):1785-8 [14679172.001]
  • [Cites] Am J Gastroenterol. 2003 Dec;98(12):2771-6 [14687831.001]
  • [Cites] Semin Liver Dis. 2004 Feb;24(1):99-106 [15085490.001]
  • [Cites] Hepatology. 2004 May;39(5):1390-7 [15122768.001]
  • [Cites] Hepatology. 2004 Jul;40(1):46-54 [15239085.001]
  • [Cites] Hepatology. 2004 Jul;40(1):177-84 [15239101.001]
  • [Cites] Hepatology. 2004 Jul;40(1):185-94 [15239102.001]
  • [Cites] J Clin Invest. 2004 Jul;114(2):224-31 [15254589.001]
  • [Cites] Diabetes. 2004 Aug;53(8):1937-41 [15189975.001]
  • [Cites] Int J Tissue React. 1987;9(4):295-306 [3623826.001]
  • (PMID = 19753129.001).
  • [ISSN] 1466-1861
  • [Journal-full-title] Mediators of inflammation
  • [ISO-abbreviation] Mediators Inflamm.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ADIPOQ protein, human; 0 / Adipokines; 0 / Adiponectin; 0 / Interleukin-6; 0 / Leptin; 0 / RETN protein, human; 0 / Resistin; 0 / Tumor Necrosis Factor-alpha
  • [Number-of-references] 98
  • [Other-IDs] NLM/ PMC2694309
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58. Bougnoux P, Hajjaji N, Couet C: The lipidome as a composite biomarker of the modifiable part of the risk of breast cancer. Prostaglandins Leukot Essent Fatty Acids; 2008 Sep-Nov;79(3-5):93-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In order to circumvent the limitations and/or bias of dietary exposure assessment tools, we have used the fatty acid composition of white adipose tissue as biomarker of past lipid intake.
  • We reappraised the role of the complete lipid profile through a comprehensive study of adipose tissue fatty acids obtained in patients with benign or malignant breast tumors.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Breast Neoplasms / epidemiology. Fatty Acids / metabolism
  • [MeSH-minor] Adipose Tissue / chemistry. Adipose Tissue / metabolism. Animals. Diet Surveys. Female. Genetic Predisposition to Disease. Humans. Risk Factors

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  • (PMID = 18930643.001).
  • [ISSN] 0952-3278
  • [Journal-full-title] Prostaglandins, leukotrienes, and essential fatty acids
  • [ISO-abbreviation] Prostaglandins Leukot. Essent. Fatty Acids
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Fatty Acids
  • [Number-of-references] 14
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59. Aust MC, Spies M, Kall S, Jokuszies A, Gohritz A, Vogt P: Posttraumatic lipoma: fact or fiction? Skinmed; 2007 Nov-Dec;6(6):266-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipomas are usually benign adipose tumors with as-yet unexplained pathogenesis and etiology.
  • A link between soft tissue trauma and the formation of lipomas has been described, with the latter being named posttraumatic lipomas.
  • The average time between soft tissue trauma and lipoma formation was 2.6 years (range, 0.5-6.0 years).
  • Pathology demonstrated capsulated and noncapsulated benign adipose tumors in 23 cases.
  • CONCLUSIONS: The pathogenetic link between soft tissue trauma and the formation of posttraumatic lipomas is still controversially discussed.
  • There are 2 potential explanations to correlate soft tissue trauma and adipose tissue tumor growth.
  • The first is the formation of so-called posttraumatic pseudolipomas by prolapsing adipose tissue through fascia resulting from direct impact.
  • A second possibility points toward lipoma formation as a result of preadipocyte differentiation and proliferation mediated by cytokine release following soft tissue trauma and hematoma formation.
  • [MeSH-major] Adipose Tissue / injuries. Lipoma / etiology. Neoplasms, Adipose Tissue / etiology. Wounds, Nonpenetrating / complications

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  • (PMID = 17975353.001).
  • [ISSN] 1540-9740
  • [Journal-full-title] Skinmed
  • [ISO-abbreviation] Skinmed
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Gokhale U, Pillai GR, Varghese PV, Samarsinghe D: Chondroid lipoma: a case report. Oman Med J; 2008 Apr;23(2):116-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondroid lipoma is a unique, uncommon benign lipomatous tumour.
  • We report such a neoplasm with brief a review of literature.

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  • (PMID = 22379550.001).
  • [ISSN] 1999-768X
  • [Journal-full-title] Oman medical journal
  • [ISO-abbreviation] Oman Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Oman
  • [Other-IDs] NLM/ PMC3282416
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61. Choi SW, Song SH: Intrapelvic lipoblastoma with massive spinal canal invasion. Childs Nerv Syst; 2007 May;23(5):581-5
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  • OBJECTS: The lipoblastoma is a rare benign pediatric neoplasm that derives from embryonic white fat cells.
  • However, this tumor with spinal invasion in children is extremely rare.
  • Histopathologic diagnosis confirmed the lipoblastoma.
  • CONCLUSION: Lipoblastoma is a rare benign neoplasm and lumbosacral invasion is unique.
  • [MeSH-major] Lipoma / pathology. Neoplasms, Adipose Tissue / pathology. Pelvic Neoplasms / pathology. Spinal Cord Neoplasms / secondary

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  • [Cites] Pediatr Surg Int. 2000;16(5-6):458-61 [10955594.001]
  • [Cites] Am J Surg Pathol. 1997 Oct;21(10):1131-7 [9331284.001]
  • [Cites] Pediatrics. 2000 Jan;105(1 Pt 1):123-8 [10617716.001]
  • [Cites] Am J Pathol. 1958 Nov-Dec;34(6):1149-59 [13583102.001]
  • [Cites] J Pediatr Surg. 2001 Jan;36(1):229-31 [11150471.001]
  • [Cites] J Pediatr Surg. 1982 Jun;17(3):277-80 [7108715.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] Histopathology. 1993 Dec;23(6):527-33 [8314236.001]
  • [Cites] Clin Imaging. 2002 Jan-Feb;26(1):23-6 [11814748.001]
  • [Cites] Pediatr Radiol. 2003 Jan;33(1):37-40 [12497236.001]
  • [Cites] J Pediatr Surg. 2001 Jun;36(6):905-7 [11381423.001]
  • (PMID = 17143644.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Coloring Agents
  •  go-up   go-down


62. Omori M, Toyoda H, Hirai T, Ogino T, Okada S: Angiomyofibroblastoma of the vulva: a large pedunculated mass formation. Acta Med Okayama; 2006 Aug;60(4):237-42
MedlinePlus Health Information. consumer health - Vulvar Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyofibroblastoma is a rare, usually small benign mesenchymal tumor that occurs in vulvar lesions of premenopausal women.
  • The maximum dimension of the tumor measured 11 cm.
  • The resected tumor was well circumscribed with a bulging and glistening cut surface.
  • In the present case, intralesional adipose tissue was present throughout the tumor.
  • There was little stromal mucin throughout the tumor.
  • [MeSH-major] Hemangioma / surgery. Neoplasms, Muscle Tissue / surgery. Vulvar Neoplasms / surgery

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  • (PMID = 16943862.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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63. Bougnoux P, Giraudeau B, Couet C: Diet, cancer, and the lipidome. Cancer Epidemiol Biomarkers Prev; 2006 Mar;15(3):416-21
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In order to circumvent the limitations and/or bias of dietary exposure assessment tools, biomarkers of past lipid intake such as the fatty acid composition of white adipose tissue have been used.
  • This article presents a reappraisal of the role of the lipid profile through a comprehensive reanalysis of adipose tissue fatty acid composition obtained in patients with benign or malignant breast tumors as well as in experimental animals during dietary interventions.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Breast Neoplasms / etiology. Dietary Fats, Unsaturated / metabolism. Fatty Acids / metabolism
  • [MeSH-minor] Adipose Tissue / metabolism. Animals. Fatty Acids, Omega-3 / metabolism. Fatty Acids, Omega-6 / metabolism. Female. Humans. Rats. Risk Assessment. Sensitivity and Specificity

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  • [Cites] Nutr Cancer. 2000;36(1):33-41 [10798214.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1496-501 [15941962.001]
  • [Cites] Int J Cancer. 2002 Mar 1;98(1):78-83 [11857389.001]
  • [Cites] IARC Sci Publ. 2002;156:403-4 [12484221.001]
  • [Cites] N Engl J Med. 2002 Dec 19;347(25):1999-2009 [12490681.001]
  • [Cites] Lancet. 2003 Jul 19;362(9379):212-4 [12885485.001]
  • [Cites] World Rev Nutr Diet. 2003;92:133-51 [14579688.001]
  • [Cites] Int J Cancer. 2004 Apr 10;109(3):449-54 [14961586.001]
  • [Cites] Nat Rev Cancer. 2004 Jul;4(7):519-27 [15229477.001]
  • [Cites] Prog Clin Biol Res. 1986;222:283-94 [3097652.001]
  • [Cites] Am J Clin Nutr. 1991 Aug;54(2):340-5 [1858698.001]
  • [Cites] Cancer Res. 1992 Apr 1;52(7 Suppl):2024s-2029s [1311987.001]
  • [Cites] Lipids. 1993 May;28(5):449-56 [8316054.001]
  • [Cites] Lipids. 1993 Sep;28(9):827-32 [8231658.001]
  • [Cites] Environ Health Perspect. 1995 Apr;103 Suppl 3:99-106 [7635122.001]
  • [Cites] Nutr Cancer. 1998;30(2):137-43 [9589432.001]
  • [Cites] Semin Cancer Biol. 1998 Aug;8(4):245-53 [9870031.001]
  • [Cites] Nutrition. 1999 Jun;15(6):523-6 [10378216.001]
  • [Cites] Curr Opin Clin Nutr Metab Care. 1999 Mar;2(2):121-6 [10453342.001]
  • [Cites] Clin Cancer Res. 2002 Feb;8(2):305-13 [11839646.001]
  • (PMID = 16537692.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Dietary Fats, Unsaturated; 0 / Fatty Acids; 0 / Fatty Acids, Omega-3; 0 / Fatty Acids, Omega-6
  • [Number-of-references] 23
  • [Other-IDs] NLM/ HALMS68759; NLM/ PMC2755770
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64. Yong M, Raza AS, Greaves TS, Cobb CJ: Fine-needle aspiration of a pleomorphic lipoma of the head and neck: a case report. Diagn Cytopathol; 2005 Feb;32(2):110-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pleomorphic lipoma is a rare soft-tissue tumor, most commonly seen in the head and neck regions of middle-aged men.
  • Aspiration of the mass showed a hypocellular specimen with atypical large and floret cells with fragments of mature fibroadipose tissue in the background.
  • Based on the clinical and cytomorphological findings, a diagnosis of pleomorphic lipoma was suggested, and it was confirmed on excision.
  • This case highlights the need to be aware of unusual benign lesions that may arise in the head and neck region.
  • Knowledge of these benign lesions will help in making the correct cytological diagnosis when these lesions are sampled by FNA.
  • [MeSH-major] Adipose Tissue / pathology. Head and Neck Neoplasms / pathology. Lipoma / pathology

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15637670.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Han Y, Liu J: [Autologous free fat particle grafting combined with bFGF to repair facial depression]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2008 Mar;22(3):339-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The pathological causes were congenital facial depression in 2 patients, hemifacial atrophy in 2, traumatic cicatrix in 5 and benign tumor removal in 3.
  • The pathological causes were: congenital facial depression in 3 patients, hemifacial atrophy in 4, traumatic cicatrix in 15 and benign tumor removal in 7.
  • [MeSH-major] Adipose Tissue / transplantation. Face / surgery. Facial Hemiatrophy / surgery. Fibroblast Growth Factor 2 / therapeutic use. Rhytidoplasty / methods
  • [MeSH-minor] Adolescent. Adult. Facial Injuries / surgery. Female. Follow-Up Studies. Humans. Injections, Subcutaneous. Male. Middle Aged. Skin Abnormalities / surgery. Tissue and Organ Harvesting / methods. Treatment Outcome. Young Adult

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  • (PMID = 18396717.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] China
  • [Chemical-registry-number] 103107-01-3 / Fibroblast Growth Factor 2
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66. Giblin E, Lynn D, Mortman K: Cervical hibernoma demonstrating uptake on Tc-99m lymphoscintigraphy. Clin Nucl Med; 2006 Nov;31(11):694-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A hibernoma is an uncommon, benign tumor composed of brown adipose tissue.
  • These tumors are by definition benign entities but, given their propensity for growth over time, they require complete extirpation to prevent recurrence.
  • [MeSH-minor] Female. Humans. Middle Aged. Radiopharmaceuticals / pharmacokinetics. Tissue Distribution

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  • (PMID = 17053387.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 556Q0P6PB1 / Technetium Tc 99m Sulfur Colloid
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67. Jung SM, Chang PY, Luo CC, Huang CS, Lai JY, Hsueh C: Lipoblastoma/lipoblastomatosis: a clinicopathologic study of 16 cases in Taiwan. Pediatr Surg Int; 2005 Oct;21(10):809-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma/lipoblastomatosis is an uncommon benign lipomatous tumor affecting mainly infants and children.
  • [MeSH-major] Lipoma / pathology. Soft Tissue Neoplasms / pathology

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  • [Cites] Genes Chromosomes Cancer. 1993 Jan;6(1):24-9 [7680218.001]
  • [Cites] Pediatr Pathol. 1986;5(2):207-16 [3763506.001]
  • [Cites] Br J Surg. 1947 Jan;34(135):282-4 [20289117.001]
  • [Cites] Acta Anaesthesiol Scand. 1997 Aug;41(7):945-6 [9265941.001]
  • [Cites] Am J Surg Pathol. 1997 Oct;21(10):1131-7 [9331284.001]
  • [Cites] Am J Pathol. 1958 Nov-Dec;34(6):1149-59 [13583102.001]
  • [Cites] J Pediatr Surg. 2001 Jan;36(1):229-31 [11150471.001]
  • [Cites] Indian J Pediatr. 2000 Apr;67(4):301-3 [10878874.001]
  • [Cites] J Pediatr Surg. 1982 Jun;17(3):277-80 [7108715.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] Pediatr Surg Int. 1998 Mar;13(2-3):213-4 [9563056.001]
  • [Cites] Histopathology. 1993 Dec;23(6):527-33 [8314236.001]
  • [Cites] J Pediatr Surg. 1993 Feb;28(2):259-61 [8437092.001]
  • [Cites] Ultrastruct Pathol. 2001 Jul-Aug;25(4):321-33 [11577778.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2001 Dec 1;61(3):265-8 [11700198.001]
  • [Cites] J Pediatr Surg. 2001 Jun;36(6):905-7 [11381423.001]
  • (PMID = 16180007.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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68. Kazakov DV, Sima R, Michal M: Hemosiderotic fibrohistiocytic lipomatous lesion: clinical correlation with venous stasis. Virchows Arch; 2005 Jul;447(1):103-6
MedlinePlus Health Information. consumer health - Varicose Veins.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemosiderotic fibrohistiocytic lipomatous lesion: clinical correlation with venous stasis.
  • Hemosiderotic fibrohistiocytic lipomatous lesion (HFLL) is a recently proposed lipomatous entity.
  • HFLL was originally suggested to be a benign reactive lesion arising due to an antecedent trauma.
  • We hypothesize that the proliferation of spindled fibroblastic and myofibroblastic cells and capillaries, erythrocyte extravasation, and hemosiderin deposition with lipomatous tissue of HFLL may simply represent an exaggerated tissue response to venous stasis in which elevated venous and capillary pressures, oxygen saturation, and edema stimulate the proliferation of the above mentioned elements and lead to erythrocyte extravasation.
  • [MeSH-major] Hemosiderosis / pathology. Histiocytosis / pathology. Lipoma / pathology. Soft Tissue Neoplasms / pathology. Varicose Veins / pathology. Venous Insufficiency / pathology
  • [MeSH-minor] Adipose Tissue / chemistry. Adipose Tissue / pathology. Biomarkers, Tumor / analysis. Female. Hemosiderin / analysis. Humans. Immunohistochemistry. Middle Aged. Treatment Outcome

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  • [Cites] Lab Invest. 1982 Jul;47(1):43-50 [7087397.001]
  • [Cites] Mod Pathol. 2000 Nov;13(11):1192-9 [11106076.001]
  • [Cites] Am J Surg Pathol. 2004 Nov;28(11):1417-25 [15489645.001]
  • [Cites] J Invest Dermatol. 2001 Apr;116(4):506-10 [11286615.001]
  • [Cites] Bull Soc Fr Dermatol Syphiligr. 1967;74(5):664-5 [5587915.001]
  • [Cites] J Dermatol. 1997 Jan;24(1):28-33 [9046737.001]
  • [Cites] Am J Surg Pathol. 1995 Sep;19(9):1010-20 [7661274.001]
  • [Cites] Arch Dermatol. 1965 Nov;92(5):515-8 [5844394.001]
  • [Cites] Hepatology. 1997 Oct;26(4):891-5 [9328310.001]
  • [Cites] Pathol Res Pract. 1989 Oct;185(4):441-4 [2602215.001]
  • [Cites] J Cutan Pathol. 1997 May;24(5):298-304 [9194583.001]
  • [Cites] Arch Dermatol. 1967 Aug;96(2):176-81 [6039154.001]
  • [Cites] Am J Hum Genet. 1992 Dec;51(6):1229-39 [1281384.001]
  • [Cites] Zentralbl Pathol. 1992;138(1):27-33 [1596481.001]
  • (PMID = 15947948.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 9011-92-1 / Hemosiderin
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69. Dreux N, Marty M, Chibon F, Vélasco V, Hostein I, Ranchère-Vince D, Terrier P, Coindre JM: Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases. Mod Pathol; 2010 Dec;23(12):1657-66

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The high mobility group A (HMGA2) gene encodes a protein that alters chromatin structure and regulates the transcription of many genes; it is implicated in both benign and malignant neoplasias, but its rearrangements are a feature of development of several mesenchymal tumors.
  • We thus analyzed 880 cases on tissue microarray and 182 cases on whole sections (211 adipocytic tumors, 628 sarcomas, 213 benign mesenchymal tumors, and 10 normal adipose tissues).
  • A nuclear immunostaining was detected in 86% of conventional and intramuscular lipomas, in 86% of well-differentiated liposarcomas and in 67% of dedifferentiated liposarcomas, as opposed to 16% of other benign adipose tumors and to 15% of non-well-differentiated liposarcoma/dedifferentiated liposarcoma sarcomas.
  • Among benign mesenchymal tumors and lesions, it was detected in 90% of nodular fasciitis and in 88% of benign fibrous histiocytomas with respective specificities of 85 and 100%, and in 90% of aggressive angiomyxoma, contrary to other vulvovaginal tumor types, which expressed HMGA2 only rarely.
  • The normal adipose tissue was always negative for HMGA2.
  • Although not specific, immunohistochemical detection of the HMGA2 protein is helpful for the distinction of normal adipose tissue from well-differentiated lesions, particularly on biopsy or on re-excision.
  • It is less sensitive than MDM2/CDK4 for dedifferentiated liposarcomas diagnosis, but it appears more specific to distinguish dedifferentiated liposarcomas from other poorly differentiated sarcomas.
  • Finally, and may be more importantly, HMGA2 is useful for the diagnosis of benign fibrous histiocytoma, nodular fasciitis and vulvovaginal benign mesenchymal tumors.
  • [MeSH-major] Biomarkers, Tumor / analysis. HMGA2 Protein / biosynthesis. Neoplasms, Connective and Soft Tissue / diagnosis. Neoplasms, Connective and Soft Tissue / metabolism
  • [MeSH-minor] Humans. Immunohistochemistry. Tissue Array Analysis

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  • (PMID = 20834238.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / HMGA2 Protein
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70. Prud'homme A, Rousselot C, de Pinieux G, Voche P, Rosset P: [Hemosiderotic fibrohistiocytic lipomatous lesion: a new entity you must remind]. Ann Chir Plast Esthet; 2007 Dec;52(6):616-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hemosiderotic fibrohistiocytic lipomatous lesion: a new entity you must remind].
  • Fatty tissues lesions are the most frequent of both benign (lipoma) and malignant tumor (liposarcoma) of soft tissues in the adult.
  • We here describe the case of female patient having a fatty tissue mass of the ankle corresponding to an hemosiderotic fibrohistiocytic lipomatous lesion (HFHLL).
  • This very rare tumour of recent description is specific of the ankle/foot area of the middle age women.
  • These lesions are always benign and frequently recur following incomplete resection.
  • This tumor may have invasive local growth and metastases have not been described so far.
  • We discuss the main differentials diagnosis and treatment.
  • [MeSH-major] Hemosiderosis / complications. Histiocytic Disorders, Malignant / complications. Histiocytic Disorders, Malignant / pathology. Leiomyoma / complications. Leiomyoma / pathology. Lipoma / complications. Lipoma / pathology. Neoplasms, Adipose Tissue / complications. Neoplasms, Adipose Tissue / pathology

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  • (PMID = 17316948.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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71. Lee KR, Seo TJ, Cho JH, Kim HI, Hur YH, Cho SB, Lee WS, Joo YE: [A case of large retroperitoneal lipoma mimicking liposarcoma]. Korean J Gastroenterol; 2010 Jun;55(6):394-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipomas are the most common benign tumors of adipose tissue among adults.
  • Laparotomy showed a large encapsulating tumor arising from retroperitoneum with fat necrosis.
  • [MeSH-major] Lipoma / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Fluorodeoxyglucose F18. Humans. Liposarcoma / diagnosis. Male. Middle Aged. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • (PMID = 20571308.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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72. Bartumeus Martínez P, Ripollés González T: [Extraadrenal retroperitoneal myelolipoma]. Actas Urol Esp; 2009 Apr;33(4):439-42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extraadrenal myelolipomas are rare benign tumors and differentiating them from other soft tissue tumors containing fat can be difficult.
  • Initially oriented as liposarcoma, the final diagnosis was obtained after surgery.
  • Computed tomography (CT), ultrasound (US) and magnetic resonance imaging (MRI) features may vary according to the major component of the tumor.
  • MRI with fat suppression and opposed-phase imaging are the best imaging tools to demonstrate the adipose tissue.

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  • (PMID = 19579898.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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73. Mete O, Rotstein L, Asa SL: Controversies in thyroid pathology: thyroid capsule invasion and extrathyroidal extension. Ann Surg Oncol; 2010 Feb;17(2):386-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Controversies surrounding diagnostic criteria that distinguish benign from malignant thyroid follicular lesions have been brought to the attention of this community.
  • Moreover, the presence of adipose tissue within the thyroid gland and its pseudocapsule implies that thyroid tumor within fat tissue cannot be accepted as a criterion of ETE by that thyroid carcinoma.
  • [MeSH-major] Connective Tissue / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Thyroid Gland / anatomy & histology

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  • (PMID = 19949881.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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74. Sachdeva MP, Goldblum JR, Rubin BP, Billings SD: Low-fat and fat-free pleomorphic lipomas: a diagnostic challenge. Am J Dermatopathol; 2009 Jul;31(5):423-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pleomorphic lipomas are benign tumors that most commonly present as subcutaneous masses in the head and neck, shoulder, or back region of middle-aged to elderly men.
  • When little or no fat is present, the diagnosis can be challenging.
  • The seventh case was an intradermal tumor from the nose of a 48-year-old woman.
  • Referring diagnoses, when provided, included myxofibrosarcoma, giant cell fibroblastoma, and granulomatous rosacea for the tumor from the nose; none considered pleomorphic lipomas.
  • When fat is absent or present in reduced amounts, clinical context and identification of classic nonlipogenic components are essential for the diagnosis of pleomorphic lipomas.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Lipoma / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Adult. Aged. Antigens, CD34 / metabolism. Diagnosis, Differential. Female. Fibrosarcoma / pathology. Giant Cell Tumors / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Rosacea / pathology

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  • (PMID = 19542913.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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75. Kim HS, Yun KJ: Adenolipoma of the thyroid gland: report of a case with diagnosis by fine-needle aspiration cytology. Diagn Cytopathol; 2008 Apr;36(4):253-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenolipoma of the thyroid gland: report of a case with diagnosis by fine-needle aspiration cytology.
  • Adenolipomas are rare benign neoplasms composed of mature adipose tissue and thyroid follicles.
  • A FNA cytology specimen showed a few benign follicular cells with adipose tissue.
  • Microscopic findings showed a solid tumor predominantly composed of mature adipose tissue intermixed with thyroid follicles.
  • The pathological diagnosis was adenolipoma of the thyroid gland.
  • The presence of adipose tissue is a common finding within the cytologic specimen, especially in obese individuals or with inadequate sampling.
  • But suspicion may be possible if excess amounts of adipose tissue are present in the submitted sample.
  • [MeSH-major] Lipoma / diagnosis. Thyroid Neoplasms / diagnosis

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18335547.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Zhang F, Xie ZJ, Ge WL, Li SL, Li YN: Tensile force produced by a lipoma in the masseteric space possibly causing hyperostosis of the angle of the mandible. Med Sci Monit; 2009 Sep;15(9):CS148-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: A lipoma is a benign tumor which may occur in the adipose tissue of any part of the body.
  • The tumor is most commonly found on the trunk and extremities.
  • Although it is the most common tumor of mesenchymal origin in the head and neck, its incidence is relatively rare.
  • Lipoma of the head and neck is usually located in subcutaneous tissue.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Hyperostosis / pathology. Lipoma / pathology. Mandible / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19721405.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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77. Koplin SA, Twohig MH, Lund DP, Hafez GR: Omental lipoblastoma. Pathol Res Pract; 2008;204(4):277-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This unusual tumor is only the eighth reported omental lipoblastoma [J. Hicks, A. Dilley, D. Patel, J.
  • Goldblum, Enzinger and Weiss's Soft Tissue Tumors, fourth ed., Mosby, St. Louis, MO, 2001, pp.
  • Lakhoo, Omental lipoblastoma in a child; diagnosis based in CT density measurements. J. Pediatr. Hematol. Oncol.
  • Alvarenga, Sonographic features of benign intraperitoneal lipomatous tumors in children-report of 4 cases. Pediatr. Radiol.
  • [MeSH-major] Neoplasms, Adipose Tissue / pathology. Omentum / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Chromosomes, Human, Pair 14. Chromosomes, Human, Pair 8. Diagnosis, Differential. Gene Expression Regulation, Neoplastic. Humans. Infant. Karyotyping. Liposarcoma, Myxoid / pathology. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18276084.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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78. Leuschner I: [Lipofibromatosis in a 6-year-old girl: a case report]. Pathologe; 2010 Mar;31(2):150-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipofibromatosis is a typical soft tissue lesion of childhood which is most likely underdiagnosed.
  • The case of a 6-year-old girl with a palmar tumor is presented.
  • The lesion showed a typical fascicular growth patter into the fatty tissue.
  • Differential diagnosis includes fibrous hamartoma of infancy.
  • Lipofibromatosis is a benign disease but recurrences are not unusual.
  • [MeSH-major] Fibroma / pathology. Lipomatosis / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adipose Tissue / pathology. Child. Diagnosis, Differential. Female. Hand / pathology. Humans. Neoplasm Invasiveness

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  • [Cites] Am J Surg Pathol. 2000 Nov;24(11):1491-500 [11075850.001]
  • [Cites] Cancer Genet Cytogenet. 2007 Dec;179(2):136-9 [18036401.001]
  • [Cites] Virchows Arch. 2008 Jan;452(1):115-7 [18066591.001]
  • [Cites] Pediatr Dev Pathol. 2009 Jul-Aug;12(4):292-6 [18939887.001]
  • (PMID = 20076960.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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79. Nga ME, Swe NN, Chen KT, Shen L, Lilly MB, Chan SP, Salto-Tellez M, Das K: PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications. Int J Exp Pathol; 2010 Feb;91(1):34-43
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The differential diagnosis of soft tissue tumours poses a considerable challenge for pathologists, especially adipocytic tumours, as these may show considerable overlap in clinical presentation and morphological features with many other mesenchymal neoplasms.
  • We investigated the immunohistochemical expression of PIM-1 kinase in 35 samples of soft tissue tumours using tissue microarray technology and 49 full sections of adipocytic (n = 26) and non-adipocytic tumours (n = 23).
  • Benign and malignant adipocytic tumours showed strong expression of PIM-1 while the non-adipocytic tumours were either negative or showed only weak staining for the protein.
  • Our results indicate that the expression of PIM-1 in adipose tissue may be a useful marker of adipocytic differentiation, in particular if the staining is both of high intensity and present in a unique, vacuolar pattern.
  • [MeSH-major] Adipocytes / enzymology. Biomarkers, Tumor / analysis. Neoplasms, Adipose Tissue / enzymology. Proto-Oncogene Proteins c-pim-1 / analysis. Sarcoma / enzymology
  • [MeSH-minor] Cell Differentiation. Diagnosis, Differential. Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Polymerase Chain Reaction. Predictive Value of Tests. RNA, Messenger / analysis. Tissue Array Analysis. Vacuoles / enzymology

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  • [Cites] Blood. 2004 Jun 15;103(12):4536-44 [14982870.001]
  • [Cites] Clin Chem. 2004 Jun;50(6):1082-6 [15161730.001]
  • [Cites] Cell. 1984 May;37(1):141-50 [6327049.001]
  • [Cites] Cell. 1989 Feb 24;56(4):673-82 [2537153.001]
  • [Cites] Int J Cancer Suppl. 1989;4:22-5 [2681009.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Nov;86(22):8857-61 [2682662.001]
  • [Cites] Leukemia. 1990 Aug;4(8):590-4 [2143796.001]
  • [Cites] Cancer. 1991 Feb 1;67(3):572-6 [1985751.001]
  • [Cites] Mol Cell Biol. 1991 Feb;11(2):1176-9 [1990273.001]
  • [Cites] J Clin Oncol. 1996 Mar;14(3):869-77 [8622035.001]
  • [Cites] J Clin Oncol. 1997 May;15(5):1831-6 [9164192.001]
  • [Cites] J Biol Chem. 1999 Jun 25;274(26):18659-66 [10373478.001]
  • [Cites] J Biol Chem. 2004 Nov 12;279(46):48319-28 [15319445.001]
  • [Cites] J Mol Biol. 2005 Apr 22;348(1):183-93 [15808862.001]
  • [Cites] Am J Surg Pathol. 2005 Aug;29(8):1025-33 [16006796.001]
  • [Cites] Cancer Res. 2005 Oct 15;65(20):9226-35 [16230383.001]
  • [Cites] Eur J Cancer. 2005 Nov;41(16):2513-27 [16213703.001]
  • [Cites] J Surg Oncol. 2005 Dec 15;92(4):326-30 [16299799.001]
  • [Cites] Histopathology. 2006 Jan;48(1):13-21 [16359533.001]
  • [Cites] Histopathology. 2006 Jan;48(1):22-31 [16359534.001]
  • [Cites] Oncogene. 2006 Jan 5;25(1):70-8 [16186805.001]
  • [Cites] J Clin Pathol. 2006 Mar;59(3):285-8 [16505280.001]
  • [Cites] Biochem Biophys Res Commun. 2006 Jul 7;345(3):989-97 [16712793.001]
  • [Cites] Br J Cancer. 2007 Mar 12;96(5):776-82 [17299397.001]
  • [Cites] Eur J Cancer. 2008 Oct;44(15):2144-51 [18715779.001]
  • [Cites] J Clin Oncol. 1999 Jun;17(6):1809-14 [10561219.001]
  • [Cites] FEBS Lett. 2000 Feb 4;467(1):17-21 [10664448.001]
  • [Cites] Nature. 2001 Jul 19;412(6844):341-6 [11460166.001]
  • [Cites] Clin Cancer Res. 2001 Dec;7(12):3977-87 [11751490.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2175-80 [11854514.001]
  • [Cites] Cancer Genet Cytogenet. 2002 Feb;133(1):1-23 [11890984.001]
  • [Cites] Biochim Biophys Acta. 2002 Dec 16;1593(1):45-55 [12431783.001]
  • [Cites] J Vet Sci. 2001 Dec;2(3):167-79 [12441685.001]
  • [Cites] Clin Cancer Res. 2003 Jun;9(6):1941-56 [12796356.001]
  • [Cites] Histopathology. 2003 Jul;43(1):1-16 [12823707.001]
  • [Cites] J Biol Chem. 2003 Nov 14;278(46):45358-67 [12954615.001]
  • [Cites] Cancer. 2003 Dec 15;98(12):2700-7 [14669292.001]
  • [Cites] CA Cancer J Clin. 2004 Mar-Apr;54(2):94-109 [15061599.001]
  • [Cites] FEBS Lett. 2004 Jul 30;571(1-3):43-9 [15280015.001]
  • (PMID = 19878356.001).
  • [ISSN] 1365-2613
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger; EC 2.7.11.1 / PIM1 protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins c-pim-1
  • [Other-IDs] NLM/ PMC2812726
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80. de Moraes M, de Matos FR, de Carvalho CP, de Medeiros AM, de Souza LB: Sialolipoma in minor salivary gland: case report and review of the literature. Head Neck Pathol; 2010 Sep;4(3):249-52
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sialolipoma is a rare benign neoplasm characterized by a well-circumscribed mass composed of neoplastic mature adipose tissue and non-neoplastic salivary gland elements.
  • Microscopically, the tumor was well-circumscribed consisting of lobular proliferation of the lipomatous tissue with thin fibrous tissue septa containing clustered salivary gland elements.
  • Both the glandular and adipose components were found in almost equal proportion.
  • No atypia in the adipose tissue was observed.
  • The definitive diagnosis was sialolipoma.
  • The age distribution was from 27 to 84 years (mean, 61.6 years) and the tumor size ranged from 0.9 to 4 cm (mean, 1.7 cm).

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  • [Cites] Histopathology. 2001 Jan;38(1):30-6 [11135044.001]
  • [Cites] Ann Diagn Pathol. 2001 Aug;5(4):207-15 [11510003.001]
  • [Cites] Int J Oral Maxillofac Surg. 2003 Feb;32(1):49-53 [12653233.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Oct;98(4):441-50 [15472660.001]
  • [Cites] Kaohsiung J Med Sci. 2004 Aug;20(8):410-4 [15473653.001]
  • [Cites] Quintessence Int. 2009 Jan;40(1):79-85 [19159027.001]
  • [Cites] J Oral Pathol Med. 2007 Oct;36(9):558-62 [17850441.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Dec;104(6):809-13 [17482843.001]
  • [Cites] Oral Maxillofac Surg. 2009 Jun;13(2):109-13 [19347375.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Oct;108(4):571-6 [19699118.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2010 Mar;267(3):459-65 [19562364.001]
  • [Cites] J Oral Pathol Med. 2006 Jul;35(6):376-8 [16762019.001]
  • (PMID = 20563675.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2923305
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81. Fernandes GC, Gupta RK, Kandalkar BM: Giant adrenal myelolipoma. Indian J Pathol Microbiol; 2010 Apr-Jun;53(2):325-6
MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adrenal myelolipoma is a rare benign tumor composed of adipose and hematopoietic tissue.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / pathology. Myelolipoma / diagnosis. Myelolipoma / pathology

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  • (PMID = 20551546.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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82. Gamss C, Chia F, Chernyak V, Rozenblit A: Giant hemorrhagic myelolipoma in a patient with sickle cell disease. Emerg Radiol; 2009 Jul;16(4):319-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adrenal myelolipoma is a rare, benign tumor consisting of adipose tissue and hematopoetic elements.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Anemia, Sickle Cell / complications. Myelolipoma / diagnosis
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Hemoglobin, Sickle. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • [Cites] J Urol. 1995 Jun;153(6):1791-3 [7752318.001]
  • [Cites] Radiographics. 2005 May-Jun;25(3):719-30 [15888621.001]
  • [Cites] Radiographics. 2005 Sep-Oct;25(5):1371-95 [16160117.001]
  • [Cites] J Magn Reson Imaging. 2003 Nov;18(5):608-11 [14579404.001]
  • [Cites] Urol Radiol. 1984;6(1):7-13 [6702033.001]
  • [Cites] Radiat Med. 2003 Sep-Oct;21(5):214-9 [14632297.001]
  • [Cites] Radiology. 2002 Nov;225(2):451-6 [12409579.001]
  • [Cites] Gan To Kagaku Ryoho. 2004 Mar;31(3):342-5 [15045937.001]
  • [Cites] J Urol. 1992 Apr;147(4):1089-90 [1552592.001]
  • [Cites] Pathol Oncol Res. 2001;7(1):72-3 [11349225.001]
  • (PMID = 18665404.001).
  • [ISSN] 1438-1435
  • [Journal-full-title] Emergency radiology
  • [ISO-abbreviation] Emerg Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Hemoglobin, Sickle
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83. Ogütcen-Toller M, Sener I, Kasap V, Cakir-Ozkan N: Maxillary myxoma: surgical treatment and reconstruction with buccal fat pad flap: a case report. J Contemp Dent Pract; 2006 Feb 15;7(1):107-16

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myxoma is a benign tumor that arises from mesenchymal tissue and is found less commonly in the bone than in soft tissue.
  • The buccal fat pad (BFP) is a lobulated mass of fatty tissue in the oromaxillofacial region, which has long been a source of grafts in facial augmentation.
  • [MeSH-major] Adipose Tissue / transplantation. Maxillary Neoplasms / surgery. Myxoma / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adult. Bone Substitutes. Bone Transplantation. Cheek. Female. Follow-Up Studies. Humans. Neoplasm Invasiveness. Oroantral Fistula / surgery. Reconstructive Surgical Procedures. Surgical Flaps. Tomography, X-Ray Computed

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  • (PMID = 16491153.001).
  • [ISSN] 1526-3711
  • [Journal-full-title] The journal of contemporary dental practice
  • [ISO-abbreviation] J Contemp Dent Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Substitutes; 0 / OsteoGraf-N
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84. Ide H, Terado Y, Nakagawa T, Saito K, Kamiyama Y, Muto S, Okada H, Imamura T, Horie S: Incidentally discovered adrenal myelolipoma associated with hyperthyroidism. Int J Clin Oncol; 2007 Oct;12(5):379-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Such tumors are composed of mature adipose tissue and hematopoietic elements, but their etiology is still unknown.
  • We report a case of adrenal myelolipoma in a patient with hyperthyroidism; this benign tumor expressed both thyroid hormone receptor alpha and beta.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Hyperthyroidism / complications. Incidental Findings. Myelolipoma / diagnosis

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  • [Cites] Wien Klin Wochenschr. 1998 May 22;110(10):379-81 [9654694.001]
  • [Cites] Physiol Rev. 2001 Jul;81(3):1097-142 [11427693.001]
  • [Cites] Cancer Lett. 2003 Mar 31;192(2):121-32 [12668276.001]
  • [Cites] Acta Pathol Jpn. 1992 Mar;42(3):221-6 [1570744.001]
  • [Cites] Am J Pathol. 1950 Mar;26(2):211-33 [15406252.001]
  • [Cites] Eur J Endocrinol. 1999 Feb;140(2):143-7 [10069658.001]
  • [Cites] Arch Ital Urol Androl. 2002 Sep;74(3):146-51 [12416010.001]
  • [Cites] Endocr Rev. 1995 Aug;16(4):460-84 [8521790.001]
  • [Cites] Neoplasma. 2004;51(4):300-5 [15254662.001]
  • [Cites] Int J Cancer. 2006 Apr 1;118(7):1653-9 [16231318.001]
  • [Cites] Am J Med Sci. 1997 Nov;314(5):338-41 [9365337.001]
  • [Cites] J Urol. 1992 Apr;147(4):1089-90 [1552592.001]
  • [Cites] Clin Endocrinol (Oxf). 1997 Jan;46(1):29-37 [9059555.001]
  • (PMID = 17929121.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Thyroid Hormone Receptors alpha; 0 / Thyroid Hormone Receptors beta
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85. Brandal P, Bjerkehagen B, Heim S: Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology. J Pathol; 2006 Feb;208(3):388-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology.
  • Cytogenetics is of considerable value when diagnosing lipomatous tumours, as different tumour types have different more or less specific chromosomal abnormalities.
  • One such entity is lipoblastoma, which is a benign lipomatous tumour that often exhibits rearrangements of chromosome bands 8q11-13, and the gene PLAG1 has been implicated as the target of these chromosomal changes.
  • All lipomatous tumours karyotyped at the Norwegian Radium Hospital were reviewed, looking for rearrangements of 8q11-13.
  • The findings raise the question as to what extent the diagnosis lipoblastoma should be based on histopathological or cytogenetic/molecular data or a combination thereof.
  • When karyotypic information from this series was combined with available literature data, it was found that the sensitivity of 8q11-13 rearrangements for diagnosing lipoblastomas when found in a lipomatous tumour was 77% and that the corresponding specificity was 98%.
  • The validity of these calculations of the diagnostic information provided by the cytogenetic findings is, of course, totally dependent on the morphological diagnosis made in each case.
  • Regardless of what the precise phenotypic diagnosis was, it is suggested that lipomatous tumours with 8q11-13 rearrangement constitute a distinct pathogenetic entity.
  • When selective therapies tailor-made against the specific pathogenetic rearrangement become available, it will become mandatory to pay more attention to the genetic constitution of the tumour cells than to their phenotypic appearance.
  • [MeSH-major] Chromosome Aberrations. Chromosomes, Human, Pair 8. Gene Rearrangement. Lipoma / genetics. Neoplasms, Adipose Tissue / genetics

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  • (PMID = 16308870.001).
  • [ISSN] 0022-3417
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Genetic Markers; 0 / PLAG1 protein, human
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86. Brown JQ, Wilke LG, Geradts J, Kennedy SA, Palmer GM, Ramanujam N: Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo. Cancer Res; 2009 Apr 1;69(7):2919-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We propose the use of a robust, biopsy needle-based, fiber-optic tool for routine clinical quantification of tumor oxygenation at the time of diagnostic biopsy for breast cancer.
  • Diffuse reflectance spectroscopy was performed on the tumors in situ before surgical resection, followed by needle-core biopsy of the optically measured tissue.
  • Hemoglobin saturation and total hemoglobin content were quantified from 76 optical spectra-tissue biopsy pairs, consisting of 20 malignant, 23 benign, and 33 adipose tissues.
  • Hemoglobin saturation in malignant tissues was significantly lower than nonmalignant tissues (P<0.002) and was negatively correlated with tumor size and pathologic tumor category (P<0.05).
  • HER2/neu-amplified tumors exhibited significantly higher total hemoglobin content (P<0.05) and significantly higher hemoglobin saturation (P<0.02), which is consistent with a model of increased angiogenesis and tumor perfusion promoted by HER2/neu amplification.
  • Diffuse reflectance spectroscopy could aid in prognosis and prediction in breast cancer via quantitative assessment of tumor physiology at the time of diagnostic biopsy.

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  • [Cites] Mol Cell Biol. 2001 Jun;21(12):3995-4004 [11359907.001]
  • [Cites] J Natl Cancer Inst. 2001 Feb 21;93(4):266-76 [11181773.001]
  • [Cites] Phys Med Biol. 2002 Aug 21;47(16):2847-61 [12222850.001]
  • [Cites] Cancer Lett. 2003 May 30;195(1):1-16 [12767506.001]
  • [Cites] Int J Hyperthermia. 2003 Sep-Oct;19(5):498-506 [12944165.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12349-54 [14514888.001]
  • [Cites] Cancer Res. 2003 Nov 15;63(22):7634-7 [14633681.001]
  • [Cites] Methods Enzymol. 2004;381:335-54 [15063685.001]
  • [Cites] Phys Med Biol. 2004 Apr 7;49(7):1165-81 [15128196.001]
  • [Cites] Nat Rev Cancer. 2004 Jun;4(6):437-47 [15170446.001]
  • [Cites] Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):4083-8 [15217943.001]
  • [Cites] Clin Cancer Res. 2004 Jul 1;10(13):4287-93 [15240513.001]
  • [Cites] Adv Exp Med Biol. 1976;75:537-46 [13621.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1981 Oct;7(10):1397-404 [7319864.001]
  • [Cites] Adv Exp Med Biol. 1983;159:391-8 [6637627.001]
  • [Cites] Adv Exp Med Biol. 1984;180:293-300 [6534106.001]
  • [Cites] Cancer Res. 1991 Jun 15;51(12):3316-22 [2040005.001]
  • [Cites] Br J Cancer. 1992 Nov;66(5):919-24 [1419637.001]
  • [Cites] Adv Exp Med Biol. 1994;345:451-8 [8079743.001]
  • [Cites] Cancer Res. 1996 Mar 1;56(5):941-3 [8640781.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Jul 1;35(4):701-8 [8690636.001]
  • [Cites] Cancer Res. 1996 Oct 1;56(19):4509-15 [8813149.001]
  • [Cites] Biochem Cell Biol. 1997;75(4):315-25 [9493954.001]
  • [Cites] Breast Cancer Res Treat. 1998 Mar;48(2):97-106 [9596481.001]
  • [Cites] Oncologist. 2004;9 Suppl 5:4-9 [15591417.001]
  • [Cites] Oncologist. 2004;9 Suppl 5:10-7 [15591418.001]
  • [Cites] Clin Cancer Res. 2004 Dec 15;10(24):8720-7 [15623657.001]
  • [Cites] Phys Med Biol. 2005 Jun 7;50(11):2573-81 [15901955.001]
  • [Cites] Acad Radiol. 2005 Aug;12(8):925-33 [16023383.001]
  • [Cites] Oncogene. 2005 Oct 13;24(45):6835-41 [16007158.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1062-71 [16512550.001]
  • [Cites] Appl Opt. 2006 Feb 10;45(5):1072-8 [16512551.001]
  • [Cites] Lasers Surg Med. 2006 Aug;38(7):714-24 [16799981.001]
  • [Cites] Int J Cancer. 2007 Apr 1;120(7):1451-8 [17245699.001]
  • [Cites] Eur Radiol. 2007 Apr;17(4):861-72 [17043737.001]
  • [Cites] Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4014-9 [17360469.001]
  • [Cites] Antioxid Redox Signal. 2007 Aug;9(8):1221-35 [17536958.001]
  • [Cites] Methods Enzymol. 2007;435:297-321 [17998060.001]
  • [Cites] Med Phys. 2008 Feb;35(2):539-45 [18383675.001]
  • [Cites] J Biomed Opt. 2008 Mar-Apr;13(2):024017 [18465980.001]
  • [Cites] Adv Exp Med Biol. 2009;645:255-60 [19227479.001]
  • [Cites] IEEE Trans Biomed Eng. 2009 Apr;56(4):960-8 [19423425.001]
  • [Cites] Neoplasia. 2000 Jan-Apr;2(1-2):26-40 [10933066.001]
  • [Cites] J Biomed Opt. 2000 Apr;5(2):131-7 [10938776.001]
  • [Cites] Int J Oncol. 2000 Nov;17(5):869-79 [11029486.001]
  • [Cites] Int J Cancer. 2000 Oct 20;90(5):237-55 [11091348.001]
  • [Cites] Semin Oncol. 2001 Apr;28(2 Suppl 8):29-35 [11395850.001]
  • (PMID = 19293184.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / F32 CA124058; United States / NCI NIH HHS / CA / R01 CA100559-05; United States / NCI NIH HHS / CA / F32 CA124082; United States / NCI NIH HHS / CA / R01 CA100559; United States / NCI NIH HHS / CA / CA124058-03; United States / NCI NIH HHS / CA / F32 CA1240582; United States / NCI NIH HHS / CA / F32 CA124058-03; United States / NCI NIH HHS / CA / CA100559-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemoglobins; EC 2.7.10.1 / Receptor, ErbB-2; S88TT14065 / Oxygen
  • [Other-IDs] NLM/ NIHMS94037; NLM/ PMC2677720
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87. Olaleye O, Fu B, Moorthy R, Lawson C, Black M, Mitchell D: Left supraclavicular spindle cell lipoma. Int J Otolaryngol; 2010;2010:942152

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Background. Spindle cell lipoma (SCL) is a benign lipomatous tumour, typically occurring in the posterior neck, shoulder or upper back of elderly males.
  • This case highlights a rare presentation of SCL and the need for pre-operative diagnosis. Case Report.
  • Conclusion. Spindle cell lipoma is a rare benign tumour and a pre-operative diagnosis based on the clinical context, imaging and immuno-histochemistry is crucial to management.

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  • [Cites] J Otolaryngol. 2006 Dec;35(6):427-9 [17380840.001]
  • [Cites] Auris Nasus Larynx. 2007 Dec;34(4):549-52 [17433592.001]
  • [Cites] Cancer Genet Cytogenet. 2007 Sep;177(2):131-4 [17854668.001]
  • [Cites] Otolaryngol Head Neck Surg. 2008 Aug;139(2):325-6 [18656742.001]
  • [Cites] J Cutan Pathol. 2009 Oct;36 Suppl 1:70-3 [19187113.001]
  • [Cites] Am J Surg Pathol. 2005 Oct;29(10):1340-7 [16160477.001]
  • [Cites] J Pathol. 2004 Jan;202(1):95-102 [14694526.001]
  • [Cites] Arch Pathol Lab Med. 2006 Jun;130(6):875-6 [16740044.001]
  • [Cites] Pol J Pathol. 2007;58(1):7-11 [17585537.001]
  • [Cites] Arch Pathol Lab Med. 2008 Jan;132(1):81-3 [18181679.001]
  • [Cites] Eur J Cardiothorac Surg. 2009 Mar;35(3):542-3 [19195907.001]
  • [Cites] Ann Diagn Pathol. 2009 Jun;13(3):173-5 [19433296.001]
  • (PMID = 20508829.001).
  • [ISSN] 1687-921X
  • [Journal-full-title] International journal of otolaryngology
  • [ISO-abbreviation] Int J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2876251
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88. Mandal RV, Duncan LM, Austen WG Jr, Nielsen GP: Infiltrating intramuscular spindle cell lipoma of the face. J Cutan Pathol; 2009 Oct;36 Suppl 1:70-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Spindle cell lipoma is a benign lipomatous tumor, which usually arises on the back of the neck, shoulder or upper back of males in the third to seventh decade of life.
  • Histologically, a proliferation of mature adipocytes, ropey collagen fibers and spindle cells within a myxoid stroma was present in the subcutaneous tissue and infiltrated between skeletal muscle fibers.
  • [MeSH-major] Lipoma / pathology. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19187113.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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89. Cifuentes M, Calleja F, Hola J, Daviú A, Jara D, Vallejos H: [Renal angiomyolipoma rupture as a cause of lumbar pain: report of one case]. Rev Med Chil; 2008 Aug;136(8):1031-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Renal angiomyolipoma is a benign tumor formed by smooth muscle, adipose tissue and blood vessels.
  • It is commonly found incidentally and its clinical manifestations are pain and abdominal mass or spontaneous tumor rupture with retroperitoneal bleeding.

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  • (PMID = 18949188.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
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90. Knight CS, Cerfolio RJ, Winokur TS: Angiomyolipoma of the anterior mediastinum. Ann Diagn Pathol; 2008 Aug;12(4):293-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyolipoma is a benign tumor composed of varying proportions of smooth muscle cells, blood vessels, and adipose tissue that most commonly occurs in the kidney.
  • [MeSH-minor] Actins / metabolism. Antigens, Neoplasm / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Melanoma-Specific Antigens. Middle Aged. Muscle, Smooth / pathology. Neoplasm Proteins / metabolism. Thymoma / pathology. Thymus Neoplasms / pathology

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  • (PMID = 18620999.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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91. Changizi V, Kheradmand AA, Oghabian MA: Application of small-angle X-ray scattering for differentiation among breast tumors. J Med Phys; 2008 Jan;33(1):19-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • As breast cancer is the most widespread cancer in women and differentiation among its tumors is important, this project compared the results of coherent X-ray scattering measurements obtained from benign and malignant breast tissues.
  • One hundred thirty-one breast-tissue samples, including normal, fibrocystic changes and carcinoma, were studied at the 6 degrees scattering angle.
  • These profiles showed a few peak positions for adipose (1.15 +/- 0.06 nm(-1)), mixed normal (1.15 +/- 0.06 nm(-1) and 1.4 +/- 0.04 nm(-1)), fibrocystic changes (1.46 +/- 0.05 nm(-1) and 1.74 +/- 0.04 nm(-1)) and carcinoma (1.55 +/- 0.04 nm(-1), 1.73 +/- 0.06 nm(-1), 1.85 +/- 0.05 nm(-1)).
  • We were able to differentiate between normal, fibrocystic changes (benign) and carcinoma (malignant) breast tissues by SAXS.

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  • [Cites] Cancer. 1997 Dec 1;80(11):2091-9 [9392331.001]
  • [Cites] Phys Med Biol. 1982 Apr;27(4):463-99 [7045898.001]
  • [Cites] Am J Epidemiol. 1980 Mar;111(3):301-8 [7361754.001]
  • [Cites] Am J Prev Med. 1998 Feb;14(2):143-53 [9631167.001]
  • [Cites] Phys Med Biol. 1999 Jul;44(7):1791-802 [10442713.001]
  • [Cites] Int J Med Sci. 2005;2(3):118-21 [16007264.001]
  • (PMID = 20041048.001).
  • [ISSN] 1998-3913
  • [Journal-full-title] Journal of medical physics
  • [ISO-abbreviation] J Med Phys
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2786093
  • [Keywords] NOTNLM ; Breast tumor / coherent scattering / small-angle X-ray scattering
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92. Ma L, Kowalski D, Javed K, Hui P: Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: a case report with p53 gene mutation analysis. Arch Pathol Lab Med; 2005 May;129(5):676-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyolipoma (AML) is the most common benign mesenchymal tumor of the kidney.
  • It belongs to the family of perivascular epithelioid cell tumors and is typically composed of blood vessels, adipose tissue, and smooth muscle- like cells, which are characteristically positive for HMB-45.
  • The tumor consisted of mostly epithelioid cells with marked nuclear pleomorphism and frequent mitoses and was positive for HMB-45.
  • The diagnosis of atypical epithelioid AML was made.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cytoplasm / ultrastructure. DNA Mutational Analysis. DNA, Neoplasm / genetics. Female. Humans. Immunohistochemistry. Intercellular Junctions / ultrastructure. Nephrectomy. Polymerase Chain Reaction. Polymorphism, Single-Stranded Conformational. Treatment Outcome

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  • (PMID = 15859641.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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93. Naik V, Arsenovic N, Reed M: Eccrine angiomatous hamartoma: a rare multifocal variant with features suggesting trauma. Dermatol Online J; 2009;15(9):6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Eccrine angiomatous hamartoma (EAH) is a rare, benign cutaneous tumor characterized by proliferation of the eccrine gland elements closely associated with capillary angiomatosis and proliferation of other dermal elements, such as adipose tissue, hair and epidermis.
  • Clinically, this condition must be differentiated from other angiomatoses and a definitive diagnosis is based upon histology.
  • Eccrine angiomatous hamartoma is a benign slowly growing lesion for which aggressive treatment is not indicated.
  • [MeSH-major] Eccrine Glands / pathology. Hamartoma / diagnosis. Sweat Gland Diseases / diagnosis
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Female. Friction. Hemangioendothelioma / diagnosis. Hemangioma / diagnosis. Hemangiosarcoma / diagnosis. Humans. Lymphangioma / diagnosis. Nevus, Blue / diagnosis. Skin / injuries. Skin Neoplasms / diagnosis

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  • (PMID = 19930993.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Röpke A, Kalinski T, Kluba U, von Falkenhausen U, Wieacker PF, Röpke M: PLAG1 activation in lipoblastoma coinciding with low-level amplification of a derivative chromosome 8 with a deletion del(8)(q13q21.2). Cytogenet Genome Res; 2007;119(1-2):33-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma is a benign uncommon soft-tissue-tumor resembling fetal adipose tissue affecting mainly children under three years of age.
  • Subsequent FISH analysis on uncultured tumor cells confirmed this result and demonstrated a low-level amplification of the chromosomal region 8pter-->8q13 and 8q21.2-->8qter.
  • RT-PCR analysis showed that the PLAG1 gene is activated in the tumor sample of the lipoblastoma analyzed, in contrast to normal fatty tissue without PLAG1 expression.

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  • [Copyright] Copyright (c) 2007 S. Karger AG, Basel.
  • (PMID = 18160779.001).
  • [ISSN] 1424-859X
  • [Journal-full-title] Cytogenetic and genome research
  • [ISO-abbreviation] Cytogenet. Genome Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / PLAG1 protein, human; 0 / RNA, Messenger
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95. Chahwala Q, Siddaraju N, Singh N, Goneppanavar M, Basu D: Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: report of a rare case. Acta Cytol; 2009 Jul-Aug;53(4):437-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Oncocytic lipoadenoma is an uncommon benign salivary gland tumor.
  • CASE: A 50-year-old woman presented with a slow-growing swelling in the left parotid region that was clinically interpreted as a soft tissue tumor, with a differential of neurofibroma/lipoma.
  • The adipose tissue background of the cytologic smears was ignored as material derived from the normal fat tissue; based on the oncocytic population of cells, a diagnosis of oncocytoma was considered.
  • However, histopathologic examination showed it to be an oncocytic lipoadenoma, a tumor we were unaware of at the time of cytodiagnosis.
  • The clinicocytopathologic correlation highlighted in our case will be useful for cytopathologists in preoperative interpretation and diagnosis.

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  • (PMID = 19697732.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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96. Suzuki T, Ueda Y, Shincho M, Mitsui Y, Higuchi Y, Maruyama T, Kondoh N, Nojima M, Yamamoto S, Hirota S, Shima H: [Myolipoma arising from the renal capsule: a case report]. Hinyokika Kiyo; 2008 May;54(5):349-52
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  • Computed tomorraphy and magnetic resonance imaging showed that the tumor was mixed with muscle and fat tissue, faintly enhanced, and located at the lower portion of the left kidney.
  • Although renal angiomyolipoma (AML) was suspected from these findings, we could not rule out a malignant tumor.
  • Histopathological examination revealed the tumor composed of smooth muscle and mature adipose tissue without cytological atypia arising from the renal capsule.
  • The tumor contained no AML-like blood vessels, and was negative for HMB-45 staining.
  • The final diagnosis was myolipoma arising from the renal capsule.
  • Myolipoma is a rare benign neoplasm in the soft tissue of retroperitoneum and abdominal cavity.
  • Since it is difficult to distinguish myolipoma from other benign and malignant tumors with fat tissue only by imaging studies, a surgical approach should be considered.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Lipoma / diagnosis

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  • (PMID = 18546859.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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97. Zwiesler D, Lewis SR, Choo YC, Martens MG: A case report of an ovarian lipoma. South Med J; 2008 Feb;101(2):205-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CASE: A 66-year-old female underwent an exploratory laparotomy and a left ovarian tumor measuring about 7 to 8 cm was removed.
  • Microscopic examination demonstrated a pattern of proliferation of benign adipose tissue with focal areas of fibrovascular septae and no other tissue of different origin.

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  • (PMID = 18364627.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Saito M, Yuasa T, Nanjo H, Tsuchiya N, Satoh S, Habuchi T: A case of testicular angiomyolipoma. Int J Urol; 2008 Feb;15(2):185-7
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 22-year-old male underwent left orchiectomy under a diagnosis of testicular tumor.
  • Pathological analysis demonstrated that it was composed of adipose tissue and vasculature with foci of myomatous component.
  • The tumor demonstrated neither cytological atypia nor widespread mitotic activity.
  • In addition, the tumor cells showed intense expression of CD34 and smooth muscle actin, whereas HMB-45 was entirely negative.
  • Although the true cellular origin and its clinical implications remain unknown, pathological and immunohistochemical studies strongly indicated benign testicular AML with a non-germ cell origin.

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  • (PMID = 18269463.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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99. Trahan S, Erickson-Johnson MR, Rodriguez F, Aubry MC, Cheville JC, Myers JL, Oliveira AM: Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartoma. Am J Surg Pathol; 2006 Oct;30(10):1326-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pulmonary hamartoma is a benign neoplasm that rarely recurs or undergoes malignant transformation.
  • Herein, we report a 48-year-old woman with a history of an incomplete excised nonchondroid pulmonary hamartoma presenting as an indolent tumor recurrence.
  • Excision of the tumor revealed a well-differentiated liposarcoma arising from the hamartomatous component.
  • These findings suggest that the formation of the 12q14-q15 chromosome amplicon, the characteristic cytogenetic finding of well-differentiated liposarcomas and the structural genomic component of the supernumerary ring and giant rod chromosomes, occurred before the morphologic changes characteristic of these malignant adipose tissue tumors and likely represents a very early molecular event in their development.

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  • (PMID = 17001166.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Genetic Markers; 0 / HMGA2 Protein; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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100. Haskell HD, Butt KM, Woo SB: Pleomorphic adenoma with extensive lipometaplasia: report of three cases. Am J Surg Pathol; 2005 Oct;29(10):1389-93
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In addition, one case consists of a proliferation of spindle cells with an interesting combination of mature adipose tissue, hyaline cartilage, and bone in the absence of ductal structures.
  • The differential diagnosis, as it pertains to other fat-containing tumors (such as lipoadenoma, spindle cell lipoma, interstitial lipomatosis, and benign mesenchymoma), is discussed.
  • It is likely that the ability of myoepithelial cells to undergo various metaplasias is the cause of the unusual histologic appearances of this tumor.
  • [MeSH-minor] Adenoma / pathology. Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Lipoma / pathology. Male. Mesenchymoma / pathology. Metaplasia / pathology. Middle Aged

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  • (PMID = 16160483.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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