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Items 1 to 100 of about 7354
6. Bunyapaiboonsri T, Yoiprommarat S, Intereya K, Kocharin K: New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861. Chem Pharm Bull (Tokyo); 2007 Feb;55(2):304-7
Hazardous Substances Data Bank. DIPHENYL ETHER .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861.
  • Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861.
  • Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC50 value of 1.3 microg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC50 values of 8.65 and 3.72 microg/ml, respectively.
  • [MeSH-minor] Animals. Cell Line, Tumor. Inhibitory Concentration 50. Magnetic Resonance Spectroscopy. Mass Spectrometry. Microbial Sensitivity Tests. Molecular Structure

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  • (PMID = 17268106.001).
  • [ISSN] 0009-2363
  • [Journal-full-title] Chemical & pharmaceutical bulletin
  • [ISO-abbreviation] Chem. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antineoplastic Agents; 0 / Phenyl Ethers; 3O695R5M1U / phenyl ether
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7. Pongcharoen W, Rukachaisirikul V, Isaka M, Sriklung K: Cytotoxic metabolites from the wood-decayed fungus Xylaria sp. BCC 9653. Chem Pharm Bull (Tokyo); 2007 Nov;55(11):1647-8
Hazardous Substances Data Bank. CYTOCHALASIN D .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytotoxic metabolites from the wood-decayed fungus Xylaria sp. BCC 9653.
  • BCC 9653 has led to the isolation of a new methyl aminobenzoate (1) together with eleven known compounds.
  • [MeSH-minor] 4-Aminobenzoic Acid / chemistry. 4-Aminobenzoic Acid / isolation & purification. 4-Aminobenzoic Acid / pharmacology. Animals. Cells, Cultured. Cercopithecus aethiops. Inhibitory Concentration 50. Molecular Structure. Spectrum Analysis. Vero Cells / drug effects

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  • (PMID = 17978529.001).
  • [ISSN] 0009-2363
  • [Journal-full-title] Chemical & pharmaceutical bulletin
  • [ISO-abbreviation] Chem. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / para-Aminobenzoates; 22144-77-0 / Cytochalasin D; 619-45-4 / methyl 4-aminobenzoate; TL2TJE8QTX / 4-Aminobenzoic Acid
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8. Mendis BG, Hemker KJ: Bloch wave analysis of the Eshelby twist contrast around end-on screw dislocations in bcc Mo. Ultramicroscopy; 2008 Aug;108(9):855-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bloch wave analysis of the Eshelby twist contrast around end-on screw dislocations in bcc Mo.

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  • (PMID = 18403123.001).
  • [ISSN] 0304-3991
  • [Journal-full-title] Ultramicroscopy
  • [ISO-abbreviation] Ultramicroscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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9. Dudarev SL, Bullough R, Derlet PM: Effect of the alpha-gamma phase transition on the stability of dislocation loops in bcc iron. Phys Rev Lett; 2008 Apr 4;100(13):135503

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of the alpha-gamma phase transition on the stability of dislocation loops in bcc iron.
  • Body-centered-cubic iron develops an elastic instability, driven by spin fluctuations, near the alpha-gamma phase transition temperature T(c) = 912 degrees C that is associated with the dramatic reduction of the shear stiffness constant c' (c(11)-c(12))/2 near T(c).
  • This reduction of c' has a profound effect on the temperature dependence of the anisotropic elastic self-energies of dislocations in iron.
  • The difference between the anisotropic elastic free energies provides the fundamental explanation for the observed dominant occurrence of the a[100], as opposed to the a/2[111], Burgers vector configurations of prismatic dislocation loops in iron and iron-based alloys at high temperatures.

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  • (PMID = 18517966.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. Medvedeva NI, Van Aken D, Medvedeva JE: Magnetism in bcc and fcc Fe with carbon and manganese. J Phys Condens Matter; 2010 Aug 11;22(31):316002
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnetism in bcc and fcc Fe with carbon and manganese.
  • Density functional theory calculations were performed to study the structure and magnetic properties of bcc (α) and fcc (γ) Fe with 3 at.
  • We find that all bcc-based Fe, Fe-C and Fe-Mn-C phases exhibit a ferromagnetic (FM) ground state, while the antiferromagnetic double-layer (AFMD) state is lowest in energy within the collinear spin approach in fcc Fe, Fe-C and Fe-Mn-C phases.
  • The states with opposite manganese magnetic moments are quasi-degenerate in bcc Fe-Mn alloy, whereas octa-site carbon stabilizes ferromagnetic coupling of the nearest manganese atom with the Fe host.

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  • (PMID = 21399372.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
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11. Jones TE, Eberhart ME, Clougherty DP, Woodward C: Electronic selection rules controlling dislocation glide in bcc metals. Phys Rev Lett; 2008 Aug 22;101(8):085505
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Electronic selection rules controlling dislocation glide in bcc metals.
  • The validity of the structure-property relationships governing the low-temperature deformation behavior of many bcc metals was brought into question with recent ab initio density functional studies of isolated screw dislocations in Mo and Ta.
  • We find that the correct form for these structure-property relationships is fully quantum mechanical, involving the coupling of electronic states with the strain field at the core of long a/<2111> screw dislocations.

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  • (PMID = 18764636.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Isaka M, Palasarn S, Sriklung K, Kocharin K: Cyclohexadepsipeptides from the insect pathogenic fungus Hirsutella nivea BCC 2594. J Nat Prod; 2005 Nov;68(11):1680-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cyclohexadepsipeptides from the insect pathogenic fungus Hirsutella nivea BCC 2594.
  • Two new cyclohexadepsipeptides, hirsutatins A (1) and B (2), were isolated from a culture filtrate of the insect pathogenic fungus Hirsutella nivea BCC 2594.
  • Hirsutatin B (2) exhibited activity against the malarial parasite Plasmodium falciparum K1 with an IC50 value of 5.8 microg/mL, while hirsutatin A (1) was inactive at a concentration of 20 microg/mL.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Drug Resistance. Hemiptera. Inhibitory Concentration 50. Molecular Structure. Mycobacterium tuberculosis / drug effects. Nuclear Magnetic Resonance, Biomolecular. Thailand. Vero Cells

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  • (PMID = 16309324.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Depsipeptides; 0 / hirsutatin A; 0 / hirsutatin B
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13. Tao X, Landau DP, Schulthess TC, Stocks GM: Spin waves in paramagnetic bcc iron: spin dynamics simulations. Phys Rev Lett; 2005 Aug 19;95(8):087207
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spin waves in paramagnetic bcc iron: spin dynamics simulations.
  • Large scale computer simulations are used to elucidate a long-standing controversy regarding the existence, or otherwise, of spin waves in paramagnetic bcc iron.
  • Spin dynamics simulations of the dynamic structure factor of a Heisenberg model of Fe with first principles interactions reveal that well defined peaks persist far above Curie temperature Tc.

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  • (PMID = 16196900.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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4. Chinworrungsee M, Kittakoop P, Saenboonrueng J, Kongsaeree P, Thebtaranonth Y: Bioactive compounds from the seed fungus Menisporopsis theobromae BCC 3975. J Nat Prod; 2006 Oct;69(10):1404-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bioactive compounds from the seed fungus Menisporopsis theobromae BCC 3975.
  • Eight new compounds (2-9), together with a known dithiodiketopiperazine (1), were isolated from the seed fungus Menisporopsis theobromae BCC 3975.
  • Compounds 1 and 4 exhibited moderate cytotoxicity against BC-1 cell lines with IC50 values of 29.2 and 57.4 microM, respectively.
  • Cytotoxicity of 1, 2, 4, and 9 against the NCI-H187 cell line showed respective IC50 values of 22.9, 20.3, 1.8, and 56.6 microM.
  • [MeSH-minor] Animals. Inhibitory Concentration 50. Microbial Sensitivity Tests. Molecular Structure. Mycobacterium tuberculosis / drug effects. Plasmodium falciparum / drug effects. Thailand

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  • (PMID = 17067151.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antimalarials; 0 / Piperazines
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15. Matsuda J, Shao H, Nakamura Y, Akiba E: The nanostructure and hydrogenation reaction of Mg50Co50 BCC alloy prepared by ball-milling. Nanotechnology; 2009 May 20;20(20):204015
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The nanostructure and hydrogenation reaction of Mg50Co50 BCC alloy prepared by ball-milling.
  • Selected-area electron diffraction patterns (SAEDPs) revealed that these nanocrystals have a body-centered cubic (BCC) structure with a lattice parameter of about 0.3 nm.
  • The SAEDPs showed polycrystalline rings corresponding to the BCC phase and the Co metal phase.

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  • (PMID = 19420663.001).
  • [ISSN] 1361-6528
  • [Journal-full-title] Nanotechnology
  • [ISO-abbreviation] Nanotechnology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Alloys; 0 / Macromolecular Substances; 0 / Magnesium Compounds; 3G0H8C9362 / Cobalt; 7YNJ3PO35Z / Hydrogen
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16. Vargo N: Cutaneous malignancies: BCC, SCC, and MM. Dermatol Nurs; 2006 Apr;18(2):183, 200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous malignancies: BCC, SCC, and MM.

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  • (PMID = 16708685.001).
  • [ISSN] 1060-3441
  • [Journal-full-title] Dermatology nursing
  • [ISO-abbreviation] Dermatol Nurs
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Yu YM, Backofen R, Voigt A: Phase-field simulation of stripe arrays on metal bcc(110) surfaces. Phys Rev E Stat Nonlin Soft Matter Phys; 2008 May;77(5 Pt 1):051605

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase-field simulation of stripe arrays on metal bcc(110) surfaces.
  • By using a phase-field model, we simulate formation and growth of stripe arrays starting with anisotropic growth of islands under the Ehrlich-Schwoebel barrier on metal bcc(110) surfaces.
  • At long times, the stripe arrays develop the quasiperiodic uniaxial structure with the selected transversal slope and the decreasing longitudinal slope as consequence of competition between coarsening and roughening.
  • At the case of the large anisotropy magnitude, the fast roughening is caused by the strongly limited attachment kinetics, where the transversal coarsening turns fast and then the uniaxial growth is broken finally.
  • For the weak roughening at the case of the reduced anisotropy magnitude, the slow transversal coarsening is achieved with the fast longitudinal coarsening, which contributes to the stripe arrays of the regular period and the increasing uniaxial length.

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  • (PMID = 18643077.001).
  • [ISSN] 1539-3755
  • [Journal-full-title] Physical review. E, Statistical, nonlinear, and soft matter physics
  • [ISO-abbreviation] Phys Rev E Stat Nonlin Soft Matter Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Pelleg J, Segel V: Calculation of the solvent and solute enhancement factors in BCC metals assuming a hypothetical structure with fourteen first nearest neighbors. J Phys Condens Matter; 2009 Apr 8;21(14):145409

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Calculation of the solvent and solute enhancement factors in BCC metals assuming a hypothetical structure with fourteen first nearest neighbors.
  • In this paper the solute and solvent enhancement factors in a hypothetical body centered cubic (b.c.c) structure having fourteen first nearest neighbors are calculated by using a statistical model for diffusion in dilute alloys.
  • Inherent to the model is the assumption of the equality of the first and second nearest neighbor jump distances, since in the b.c.c structure the difference between these distances, respectively, is only ∼13.5%.
  • Correlation effects are implicit in the calculated values of b and B.
  • The results of the fitting provide values for the frequency ratios, the additional energies required to form a vacancy in the vicinity of a solute and for the binding energies between solute pairs, i.e., between the reference and tracer solute.
  • Values of b and B in several dilute alloys were calculated at different temperatures.
  • In general there is a good agreement between experimental and calculated values of b and B in the alloys tested.
  • The equations for b and B can be used for temperatures where no experimental data exist.

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  • (PMID = 21825340.001).
  • [ISSN] 0953-8984
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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19. Morley A, Sha G, Hirosawa S, Cerezo A, Smith GD: Determining the composition of small features in atom probe: bcc Cu-rich precipitates in an Fe-rich matrix. Ultramicroscopy; 2009 Apr;109(5):535-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Determining the composition of small features in atom probe: bcc Cu-rich precipitates in an Fe-rich matrix.
  • In the case of very small second-phase precipitates, the region affected by trajectory overlaps may extend to the centre of the precipitate prohibiting a direct measurement of composition.
  • The concentration of Fe in the precipitate phase is shown to be a function of ageing temperature.

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  • (PMID = 19028011.001).
  • [ISSN] 0304-3991
  • [Journal-full-title] Ultramicroscopy
  • [ISO-abbreviation] Ultramicroscopy
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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20. Maruyama K, Shin M, Tago M, Kurita H, Kawamoto S, Morita A, Kirino T: Gamma knife surgery for arteriovenous malformations involving the corpus callosum. J Neurosurg; 2005 Jan;102(s_supplement):49-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma knife surgery for arteriovenous malformations involving the corpus callosum.
  • OBJECT: The purpose of this study was to evaluate the safety and efficacy of gamma knife surgery (GKS) for the treatment of arteriovenous malformations (AVMs) involving the corpus callosum.
  • METHODS: Thirty-two patients aged from 7 to 65 years (median 25 years) with AVMs of the corpus callosum underwent GKS between 1990 and 2002.
  • CONCLUSIONS: Gamma knife surgery is a safe and effective treatment for selected patients with AVMs involving the corpus callosum, and it carries a low risk of damaging adjacent critical vascular structures.

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  • (PMID = 28306438.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; arteriovenous malformation / corpus callosum / gamma knife surgery / stereotactic radiosurgery
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21. Gercovich N, Gil Deza E, Russo M, Garcia Gerardi C, Diaz C, Morgenfeld E, Rolnik B, Emina J, Rivarola E, Gercovich FG: Early-stage male breast cancer: A 10-year experience. J Clin Oncol; 2009 May 20;27(15_suppl):e11630

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early-stage male breast cancer: A 10-year experience.
  • : e11630 Introduction: Male breast cancer is very rare, representing only between 0.7% and 1% of all breast cancers, and only half of them are early stage cases.
  • OBJECTIVE: The present study has been designed with the aim of studying retrospectively the clinical onset and evolution of male invasive breast cancer patients (stages I and II) treated at IOHM between 1997 and 2008.
  • METHODS: The records of 3,000 breast cancer cases followed between 1997 and 2008 were searched, looking for male stage I and II breast cancer patients.
  • Tumoral type= Invasive Ductal Carcinoma 12 pt.
  • Tumoral subtype= NOS 9 pt (75%) Apocrine 2 pt (17%) Micropapillar 1 pt (8%).
  • Twelve stage I and II male breast cancer patients were identified out of 3000 (0.4%) breast cancer cases diagnosed and followed in the past 10 years at the IOHM.
  • 2. Mastectomy was the surgical procedure in 11 of the 12 cases 3.

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  • (PMID = 27961181.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Booth CM, Li G, Mackillop WJ: The impact of socioeconomic status (SES) on stage of cancer at time of diagnosis: A population-based study in Ontario, Canada. J Clin Oncol; 2009 May 20;27(15_suppl):6505

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The impact of socioeconomic status (SES) on stage of cancer at time of diagnosis: A population-based study in Ontario, Canada.
  • : 6505 Background: Lower SES is known to be associated with worsened cancer survival.
  • Here we evaluate the impact of SES on stage of cancer at diagnosis in Ontario which has universal health insurance.
  • METHODS: All incident cases of breast, colon, rectal, non-small cell lung, cervical and larynx cancer diagnosed in Ontario 2003-2005 were identified using the Ontario Cancer Registry.
  • Stage information is only captured routinely for patients seen at Ontario's 8 Regional Cancer Centers (RCCs).
  • Using a best stage grouping approach, cases were assigned stage based on pathologic TNM if available and clinical TNM otherwise.
  • Using postal code at time of diagnosis cases were assigned to quintiles (Q); Q1 represents the communities where the poorest 20% of the Ontario population resided.
  • RESULTS: Stage at diagnosis was available for 19,239/23,254 (83%) of cases seen at RCCs.
  • Among cases with breast cancer, those in Q1 were less likely to have stage I disease (43 vs 47%, p = 0.004) and more likely to have stage IV disease (5 vs 4%, 0.008) than Q2-5.
  • With lung cancer, cases in Q1 were more likely to have stage I disease compared to Q2-5 (16 vs 13%, p = 0.015).
  • Distribution of stage I and stage IV disease did not differ by SES across other individual diseases.
  • However, for all 6 cancers combined, cases in Q1 were less likely than Q2-5 to have stage I disease (27 vs 30%, p = 0.001) and more likely to have stage IV disease (21 vs 18%, p < 0.0001).
  • We found significant gradients in 3-year overall survival across Q1-Q5 for breast (5% absolute difference in survival, p < 0.001), colon (4%, p = 0.049), and cervical (18%, p = 0.031) cancers.
  • CONCLUSIONS: Despite universal health care, SES remains associated with survival among patients with cancer in Ontario.
  • These data suggest that the difference in outcome is only partially explained by differences in stage at diagnosis.

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  • (PMID = 27964005.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Maiti B, Kundranda MN, Jin T, Spiro TP, Daw HA: The association of metabolic syndrome with triple-negative breast cancer. J Clin Oncol; 2009 May 20;27(15_suppl):1038

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The association of metabolic syndrome with triple-negative breast cancer.
  • : 1038 Background: Metabolic syndrome, a conglomerate of obesity, insulin resistance, hypertriglyceridemia, low HDL (high density lipoprotein), and hypertension is associated with an increased risk of breast cancer.
  • However, no clear association has been shown between the highly aggressive triple-negative breast cancer and metabolic syndrome.
  • METHODS: In a retrospective review we compared triple-negative and non-triple-negative breast cancer cases for the presence of metabolic syndrome by NCEP (National Cholesterol Education Program) or AACE (American Association of Clinical Endocrinologists) definitions.
  • Data on metabolic syndrome criteria, tumor size, grade, lymph node status, and ductal carcinoma in situ (DCIS) were reviewed.
  • RESULTS: The entire cohort of 176 patients (12.5% African-American) with median age 56.5 years (range 26-91 years) comprised of 86 triple-negative cases and 90 non-triple-negative cases.
  • A statistically significant association of triple-negative breast cancer with metabolic syndrome was observed.
  • Contrary to blood glucose, triglyceride, or HDL levels, which independently showed significant association with triple-negative breast cancer, hypertension, or BMI showed no independent association.
  • Additionally, triple-negative tumors displayed a significantly higher histologic grade and relative paucity of ductal carcinoma in situ (DCIS) when compared to the non-triple negative tumors (p < 0.001).
  • CONCLUSIONS: The data suggests that the metabolic syndrome is significantly more prevalent in triple-negative breast cancer patients when compared to the non-triple-negative patients.
  • Additionally, triple-negative breast cancer showed a significantly higher histologic grade and a relative absence of DCIS.
  • Whether the presence of metabolic syndrome preferentially increases the risk of developing triple-negative-breast cancer needs to be elucidated by future prospective studies.

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  • (PMID = 27961078.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Visram H, Dent SF: Toxicities and adherence rates of hormone treatment in male breast cancer patients treated at a tertiary care center. J Clin Oncol; 2009 May 20;27(15_suppl):e11613

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Toxicities and adherence rates of hormone treatment in male breast cancer patients treated at a tertiary care center.
  • : e11613 Background: Male breast cancer (BC) comprises approximately 1% of all breast cancer cases, and over 80% of male BC tumours express the estrogen receptor (ER).
  • METHODS: We conducted a retrospective chart review of 24 pts diagnosed with male BC at the Ottawa Regional Cancer Centre from 1986-2003.

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  • (PMID = 27961143.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Hartmann F, Kosmidis M, Mühleisen B, French LE, Hofbauer GF: Retinoic acid receptor isoform mRNA expression differs between BCC and SCC of the skin. Arch Dermatol; 2010 Jun;146(6):675-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retinoic acid receptor isoform mRNA expression differs between BCC and SCC of the skin.
  • [MeSH-major] Carcinoma, Basal Cell / genetics. Carcinoma, Squamous Cell / genetics. RNA, Messenger / genetics. RNA, Neoplasm / genetics. Receptors, Retinoic Acid / genetics. Skin Neoplasms / genetics

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  • (PMID = 20566936.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Receptors, Retinoic Acid
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26. Douglas HE, Agarwal R, Lam DG: 'Teenage BCC: to tan or not to tan?'. J Plast Reconstr Aesthet Surg; 2008 Oct;61(10):1245-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 'Teenage BCC: to tan or not to tan?'.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 18541465.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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27. Kannan RY, Tan EK, Freedlander E: Minimising false positive margins in BCC excision: point of technique. J Plast Reconstr Aesthet Surg; 2008 Sep;61(9):1072

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Minimising false positive margins in BCC excision: point of technique.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Facial Neoplasms / surgery. Mohs Surgery / methods

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  • (PMID = 18639507.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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28. Zhang L, Shu X, Jin S, Zhang Y, Lu GH: First-principles study of He effects in a bcc Fe grain boundary: site preference, segregation and theoretical tensile strength. J Phys Condens Matter; 2010 Sep 22;22(37):375401
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First-principles study of He effects in a bcc Fe grain boundary: site preference, segregation and theoretical tensile strength.
  • We calculate the formation and segregation energies for different substitutional and interstitial cases in order to determine the site preference and the segregation properties of He in the Fe GB.

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  • (PMID = 21403193.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 206GF3GB41 / Helium; E1UOL152H7 / Iron
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29. Shapiro G, Kwak E, Baselga J, Rodon J, Scheffold C, Laird AD, Bedell C, Edelman G: Phase I dose-escalation study of XL147, a PI3K inhibitor administered orally to patients with solid tumors. J Clin Oncol; 2009 May 20;27(15_suppl):3500

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In preclinical cancer models XL147 is cytostatic or cytoreductive as monotherapy and enhances the efficacy of targeted agents and chemotherapeutics.
  • Drug-related toxicities included grade 3 skin rash (3 pts), grade 3 arterial thrombosis (1 pt), grade 2 transaminase elevation (1 pt), and grade 1 hyperglycemia (4 pts).
  • XL147 reached steady-state plasma concentrations by Day 15-20.
  • XL147 reduced levels of phosphorylated PI3K pathway components in PBMCs, hair, skin, and tumor tissues in an exposure-dependent manner.
  • As of December 2008, 6 pts (3 NSCLC, 1 BCC, 1 NHL, 1 PC) continued on study >6 months including 3 >10 months (NHL, NSCLC, BCC).
  • The most common drug-related toxicity was skin rash.
  • Prolonged stable disease has been observed.

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  • (PMID = 27961287.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Pittayakhajonwut P, Dramae A, Madla S, Lartpornmatulee N, Boonyuen N, Tanticharoen M: Depsidones from the endophytic fungus BCC 8616. J Nat Prod; 2006 Sep;69(9):1361-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Depsidones from the endophytic fungus BCC 8616.
  • Three new depsidones (1-3) have been isolated from the endophytic fungus BCC 8616 and their structures analyzed on the basis of spectroscopic data interpretation.
  • Compound 1 exhibited weak cytotoxic activity against breast and epidermoid carcinoma cell lines.
  • [MeSH-minor] Depsides. Drug Screening Assays, Antitumor. Humans. KB Cells. Molecular Structure. Nuclear Magnetic Resonance, Biomolecular. Thailand

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  • (PMID = 16989536.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Depsides; 0 / Lactones; 3580-77-6 / depsidone
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31. Fitzgerald SP, Nguyen-Manh D: Peierls potential for crowdions in the bcc transition metals. Phys Rev Lett; 2008 Sep 12;101(11):115504

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peierls potential for crowdions in the bcc transition metals.
  • The analysis is guided by the group-specific trend in the shapes of the periodic lattice potentials calculated for the body-centered-cubic transition metals in groups 5B and 6B of the periodic table.

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  • (PMID = 18851296.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Jaatinen A, Achim CV, Elder KR, Ala-Nissila T: Thermodynamics of bcc metals in phase-field-crystal models. Phys Rev E Stat Nonlin Soft Matter Phys; 2009 Sep;80(3 Pt 1):031602
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thermodynamics of bcc metals in phase-field-crystal models.
  • We examine the influence of different forms of the free-energy functionals used in the phase-field-crystal (PFC) model, and compare them with the second-order density-functional theory (DFT) of freezing, by using bcc iron as an example case.
  • We show that this functional reproduces reasonable values for both bulk and surface properties of bcc iron, and therefore it should be useful in modeling bcc materials.

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  • (PMID = 19905118.001).
  • [ISSN] 1550-2376
  • [Journal-full-title] Physical review. E, Statistical, nonlinear, and soft matter physics
  • [ISO-abbreviation] Phys Rev E Stat Nonlin Soft Matter Phys
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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33. Liu Y, Nie H, Bansil R, Steinhart M, Bang J, Lodge TP: Kinetics of disorder-to-fcc phase transition via an intermediate bcc state. Phys Rev E Stat Nonlin Soft Matter Phys; 2006 Jun;73(6 Pt 1):061803
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kinetics of disorder-to-fcc phase transition via an intermediate bcc state.
  • Time-resolved small-angle x-ray scattering measurements reveal that a long-lived intermediate bcc state forms when a poly(styrene-b-isoprene) diblock copolymer solution in an isoprene selective solvent is rapidly cooled from the disordered micellar fluid at high temperature to an equilibrium fcc state.
  • The kinetics of the epitaxial growth of the [111] fcc peak from the [110] bcc peak was obtained by fitting the scattering data to a simple model of the transformation.
  • The growth of the [111] fcc peak agrees with the Avrami model of nucleation and growth kinetics with an exponent n=1.4, as does the initial decay of the [110] bcc peak, with an exponent n=1.3.

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  • (PMID = 16906856.001).
  • [ISSN] 1539-3755
  • [Journal-full-title] Physical review. E, Statistical, nonlinear, and soft matter physics
  • [ISO-abbreviation] Phys Rev E Stat Nonlin Soft Matter Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Johnson DF, Carter EA: Nonadiabaticity in the iron bcc to hcp phase transformation. J Chem Phys; 2008 Mar 14;128(10):104703
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonadiabaticity in the iron bcc to hcp phase transformation.
  • Iron is known to undergo a pressure-induced phase transition from the ferromagnetic (FM) body-centered-cubic (bcc) alpha-phase to the nonmagnetic (NM) hexagonal-close-packed (hcp) epsilon-phase, with a large observed pressure hysteresis whose origin is still a matter of debate.
  • Long ago, Burgers [Physica (Amsterdam) 1, 561 (1934)] proposed an adiabatic pathway for bcc to hcp transitions involving crystal shear followed by atom shuffles.
  • The energy profile for this phase transition path exhibits a cusp at the TS and closely follows bcc and hcp diabatic energy wells.
  • Fluctuations in the positions of FM bcc iron atoms near the TS induce magnetic quenching (akin to solvent fluctuations inducing ET), which then promotes NM hcp iron formation (akin to solvent reorganization after ET).

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  • (PMID = 18345915.001).
  • [ISSN] 0021-9606
  • [Journal-full-title] The Journal of chemical physics
  • [ISO-abbreviation] J Chem Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Kozyreva ON, Konnikov N: The incidence of non-melanoma skin cancer after a single field treatment with aminolevulinic acid and blue light photodynamic therapy. J Clin Oncol; 2009 May 20;27(15_suppl):e14646

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The incidence of non-melanoma skin cancer after a single field treatment with aminolevulinic acid and blue light photodynamic therapy.
  • : e14646 Background: Non-melanoma skin cancer (NMSC) is the most common form of human cancer.
  • RESULTS: 43 Caucasian males (range 59- 87 yrs), 37 (87%) had history of NMSC on the face or scalp, 32 (78%) had basal cell carcinoma (BCC), 11 (22%) squamous cell carcinoma (SCC), 100% of patients had multiple (>4) AKs prior to treatment and 23 (75% ) had moderate to severe DH determined by Griffiths scale.
  • Prior to ALA-PDT 74 NMSC's were documented: 40 (54%) BCC and 34 (46%) SCC.
  • 46 NMSC's were documented following ALA-PDT: 22 (48%) BCC and 24 (52%) SCC.
  • Prior to ALA-PDT, the frequency of BCC averaged 2 [IQR 1 to 3, max=4], and the frequency of SCC averaged 1 [IQR 1 to 1, max=3].
  • Following ALA-PDT, the occurrence of BCC averaged 1 [IQR 0 to 1, max=5], and that of SCC averaged 1 [IQR 0 to 2, max= 4].
  • The difference between BCC frequency before and after ALA-PDT treatment shown a significant reduction in BCC incidence (P = 0.0018).
  • No such differences were observed between the frequency of SCC before and after ALA-PDT (P=0.6230) Conclusions: A single ALA-PDT treatment to the face or scalp in high risk patients significantly reduces the incidence of BCC, the incidence of SCC was not reduced.

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  • (PMID = 27964235.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Wickless SC, McNulty M, Lichon VC: Focally pigmented pink plaque on the back. Concomitant melanoma in situ, basal cell carcinoma (BCC), and angioma. Arch Dermatol; 2010 Jul;146(7):789-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Focally pigmented pink plaque on the back. Concomitant melanoma in situ, basal cell carcinoma (BCC), and angioma.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Hemangioma / diagnosis. Melanoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Biopsy. Diagnosis, Differential. Humans. Male

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  • (PMID = 20644044.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Jirakulaporn T, Mathew J, Lindgren BR, Dudek AZ: Efficacy of capecitabine in secondary prevention of skin cancer in solid organ-transplanted recipients (OTR). J Clin Oncol; 2009 May 20;27(15_suppl):1519

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy of capecitabine in secondary prevention of skin cancer in solid organ-transplanted recipients (OTR).
  • : 1519 Background: Skin cancers are the most common malignancies in OTR.
  • Topical 5% 5-FU has been used to successfully treat squamous cell carcinoma (SCC) in situ and actinic keratosis (AK).
  • Capecitabine, an orally-administered prodrug of 5-FU, in combination with interferon was shown to be effective in the treatment of advanced SCC of the skin.
  • This study was to determine the efficacy of low-dose capecitabine in secondary prevention of the skin cancers in OTR.
  • METHODS: OTR who developed recurrent skin cancers, SCC, and/or basal cell carcinoma (BCC), were given low-dose capecitabine 1g/m2 divided in two daily doses, day 1-14 of 21-day treatment cycle.
  • Skin surveillances were performed by dermatologists every 1 to 3 months.
  • Cumulative incidence rates of SCC, BCC, and AK before and after treatment were scored and statistically compared for each patient with a non-parametric Wilcoxon signed-rank test.
  • Mean incidence rates of SCC, BCC, and AK before treatment were 0.45, 0.05, and 4.99 lesions per month, respectively.
  • Mean incidence rates of SCC, BCC, and AK after treatment were 0.22, 0.04, and 2.80 lesions per month, respectively.
  • The differences in incidence rates of SCC, BCC, and AK before and after treatment were 0.24, 0.02, and 2.08 lesions per month with p value of 0.048, 0.844, and 0.151, respectively.
  • Age and the number of transplants were not significantly related to the change in incidence rates for all skin lesion types.

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  • (PMID = 27964327.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Haritakun R, Srikitikulchai P, Khoyaiklang P, Isaka M: Isariotins A-D, alkaloids from the insect pathogenic fungus Isaria tenuipes BCC 7831. J Nat Prod; 2007 Sep;70(9):1478-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isariotins A-D, alkaloids from the insect pathogenic fungus Isaria tenuipes BCC 7831.
  • Isariotins A-D (1- 4), alkaloids possessing a unique bicyclo[3.3.1]nonane ring, were isolated from the insect pathogenic fungus Isaria tenuipes BCC 7831.
  • [MeSH-minor] Animals. Drug Screening Assays, Antitumor. Fungi / drug effects. Molecular Structure. Mycobacterium tuberculosis / drug effects. Plasmodium falciparum / drug effects

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  • (PMID = 17822299.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alkaloids
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39. Liu ZL, Cai LC, Chen XR, Wu Q, Jing FQ: Ab initio refinement of the thermal equation of state for bcc tantalum: the effect of bonding on anharmonicity. J Phys Condens Matter; 2009 Mar 4;21(9):095408

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ab initio refinement of the thermal equation of state for bcc tantalum: the effect of bonding on anharmonicity.
  • We report a detailed ab initio study for body-centered-cubic (bcc) Ta within the framework of the quasiharmonic approximation (QHA) to refine its thermal equation of state and thermodynamic properties.

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  • (PMID = 21817394.001).
  • [ISSN] 0953-8984
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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40. Izquierdo M, Dávila ME, Avila J, Ascolani H, Teodorescu CM, Martin MG, Franco N, Chrost J, Arranz A, Asensio MC: Epitaxy and magnetic properties of surfactant-mediated growth of bcc cobalt. Phys Rev Lett; 2005 May 13;94(18):187601

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epitaxy and magnetic properties of surfactant-mediated growth of bcc cobalt.
  • High resolution core level photoemission spectroscopy, photoelectron diffraction, and x-ray magnetic circular dicroism (XMCD) have been used to characterize the structural and magnetic properties of bcc-cobalt films grown on GaAs(110) substrates by using Sb as a surfactant.

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  • (PMID = 15904410.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Tomas S: Difficult to diagnose skin cancer--the 'aggressive' BCC. Aust Fam Physician; 2009 Jul;38(7):492-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Difficult to diagnose skin cancer--the 'aggressive' BCC.
  • BACKGROUND: Basal cell carcinomas (BCCs) are common, and are regularly diagnosed and managed by Australian general practitioners.
  • OBJECTIVE: This article summarises the types, clinical features, treatment and follow up of BCCs.
  • Two cases histories are also presented that highlight the difficulties with diagnosing and treating aggressive BCC.
  • DISCUSSION: Aggressive BCCs can invade widely before exhibiting obvious clinical signs.
  • Suspicious skin lesions should have an adequate biopsy taken to guide management options.
  • Complete BCC excision is usually the best treatment, but particular care should be taken when treating lesions on cosmetically or functionally sensitive areas.
  • Recurrent disease can also be difficult and disfiguring to treat.
  • Specialist involvement will be needed for the management of some BCCs.
  • Basal cell carcinomas can recur years after treatment.
  • Regular skin checks are important for high risk patients.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Dermoscopy. Humans. Male. Mohs Surgery. Neoplasm Invasiveness. Surgical Flaps

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  • (PMID = 19575067.001).
  • [ISSN] 0300-8495
  • [Journal-full-title] Australian family physician
  • [ISO-abbreviation] Aust Fam Physician
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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42. Unagul P, Wongsa P, Kittakoop P, Intamas S, Srikitikulchai P, Tanticharoen M: Production of red pigments by the insect pathogenic fungus Cordyceps unilateralis BCC 1869. J Ind Microbiol Biotechnol; 2005 Apr;32(4):135-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Production of red pigments by the insect pathogenic fungus Cordyceps unilateralis BCC 1869.
  • Production of red pigments (naphthoquinones) by the insect pathogenic fungus Cordyceps unilateralis BCC 1869 was investigated in this study.
  • Cultivation conditions, including temperature, intitial pH of medium, and aeration, were optimised to improve the yield of total naphthoquinones in shake-flask culture of C. unilateralis.
  • An extraction process for isolation of the targeted naphthoquinone, 3,5,8-trihydroxy-6-methoxy-2-(5-oxohexa-1,3-dienyl)-1,4-naphthoquinone (3,5,8-TMON), from a culture of C. unilateralis, was also developed.
  • The stability of 3,5,8-TMON was very high, even upon exposure to strong sunlight (70,000 lx), high temperature up to 200 degrees C, and acid and alkali solutions at concentrations of 0.1 M.
  • [MeSH-minor] Animals. Culture Media. Fermentation. Hydrogen-Ion Concentration. Industrial Microbiology / methods. Oxygen / pharmacology. Temperature

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  • (PMID = 15891934.001).
  • [ISSN] 1367-5435
  • [Journal-full-title] Journal of industrial microbiology & biotechnology
  • [ISO-abbreviation] J. Ind. Microbiol. Biotechnol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Culture Media; 0 / Naphthoquinones; 0 / Pigments, Biological; S88TT14065 / Oxygen
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43. Jones TE, Eberhart ME, Clougherty DP: Topology of the spin-polarized charge density in bcc and fcc iron. Phys Rev Lett; 2008 Jan 11;100(1):017208
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Topology of the spin-polarized charge density in bcc and fcc iron.
  • We report the first investigation of the topology of spin-polarized charge density, specifically in bcc and fcc iron.
  • While the total spin-density is found to possess the topology of the non-magnetic prototypical structures, the spin-polarized charge densities of bcc and high-spin fcc iron are atypical.
  • In these cases, the two spin densities are correlated: the spin-minority electrons have directional bond paths and deep minima, while the spin-majority electrons fill these holes, reducing bond directionality.

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  • (PMID = 18232817.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Isaka M, Chinthanom P, Supothina S, Tobwor P, Hywel-Jones NL: Pyridone and tetramic acid alkaloids from the spider pathogenic fungus Torrubiella sp. BCC 2165. J Nat Prod; 2010 Dec 27;73(12):2057-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyridone and tetramic acid alkaloids from the spider pathogenic fungus Torrubiella sp. BCC 2165.
  • Torrubiellones A-D (1-4), new pyridone and tetramic acid alkaloids, were isolated from the spider pathogenic fungus Torrubiella sp. BCC 2165.
  • [MeSH-minor] Animals. Inhibitory Concentration 50. Molecular Structure. Plasmodium falciparum / drug effects

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  • (PMID = 21090800.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alkaloids; 0 / Antimalarials; 0 / Antineoplastic Agents; 0 / Pyridones; 0 / Pyrrolidinones; 0 / torrubiellone A; 503-83-3 / tetramic acid
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45. Sieron A, Gibinski P, Pustelny T, Kwiatek S, Opilski Z, Kawczyk-Krupka A, Woznica T, Maciak E, Kubica W, Urbanczyk M, Latos W: Optical biopsy using spectral camera in BCC and oral leukoplakia. Photodiagnosis Photodyn Ther; 2008 Dec;5(4):271-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optical biopsy using spectral camera in BCC and oral leukoplakia.
  • Basal cell carcinoma is one of the most common neoplasmatic diseases of the skin.
  • Early diagnosis of both diseases gives very good treatment results.
  • Spectroscopy is an objective method showing concentration and emission spectrum of protoporphyrin IX.
  • Fluorescence spectroscopy is based on searching of emission peaks of photosensitizer in areas of BCC and oral leukoplakia.
  • 20 patients with histopathologically confirmed BCC and 10 with oral leukoplakia were examinated with spectral camera and with Xillix Onco Life system 8h after local instillation of delta aminolevulinic acid.
  • All of spectral lines taken from neoplasmatic tissues were compared with spectral lines taken from healthy tissues in symmetrical areas of body.
  • All of spectral lines taken from neoplasmatic tissues showed significant peak at 630 nm in the area of BCC and oral leukoplakia in all of the examinated patients.
  • [MeSH-major] Biopsy / methods. Carcinoma, Basal Cell / diagnosis. Image Interpretation, Computer-Assisted / methods. Leukoplakia, Oral / diagnosis. Microscopy, Fluorescence / methods. Skin Neoplasms / diagnosis. Spectrometry, Fluorescence / methods

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  • (PMID = 19356670.001).
  • [ISSN] 1873-1597
  • [Journal-full-title] Photodiagnosis and photodynamic therapy
  • [ISO-abbreviation] Photodiagnosis Photodyn Ther
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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46. Ikeda M, Yamasaki T, Kaneta C: First-principles analysis of C2H2 molecule diffusion and its dissociation process on the ferromagnetic bcc-Fe110 surface. J Phys Condens Matter; 2010 Sep 29;22(38):384214

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First-principles analysis of C2H2 molecule diffusion and its dissociation process on the ferromagnetic bcc-Fe110 surface.
  • Using the projector-augmented plane wave method, we study diffusion and dissociation processes of C(2)H(2) molecules on the ferromagnetic bcc-Fe(110) surface and investigate the formation process of graphene created by C(2)H(2) molecules.
  • In order to study the diffusion process of the C(2)H(2) molecule, the barrier height energies for the C atom, C(2)-dimer and CH as well as the C(2)H(2) molecule are estimated using the nudged elastic band method.
  • The barrier height energy for C(2)H(2) is 0.71 eV and this indicates that the C(2)H(2) diffuses easily on this FM bcc-Fe(110) surface.
  • We further investigate the two step dissociation process of C(2)H(2) on Fe.
  • The first step is the dissociation of C(2)H(2) into C(2)H and H, and the second step is that of C(2)H into C(2) and H.
  • These energies are relatively small compared to the dissociation energy 7.5 eV of C(2)H(2) into C(2)H and H in the vacuum.
  • We further investigate the initial formation process of graphene by increasing the coverage of C(2)H(2).
  • The formation process of the benzene molecule on the FM bcc(110) surface is also discussed.
  • We find that there exists a critical coverage of C(2)H(2) which characterizes the beginning of the formation of the graphene.

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  • (PMID = 21386548.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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47. Bunyapaiboonsri T, Yoiprommarat S, Khonsanit A, Komwijit S: Phenolic glycosides from the filamentous fungus Acremonium sp. BCC 14080. J Nat Prod; 2008 May;71(5):891-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phenolic glycosides from the filamentous fungus Acremonium sp. BCC 14080.
  • New phenolic mono- and digalactopyranosides (1 and 2), their aglycone KS-501a (3), and a new phenolic 4-O-methylglucopyranoside (4) were isolated from the filamentous fungus Acremonium sp. BCC 14080.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Drug Screening Assays, Antitumor. Humans. Hydroxybenzoates / chemistry. Hydroxybenzoates / isolation & purification. Hydroxybenzoates / pharmacology. Inhibitory Concentration 50. Molecular Structure

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  • (PMID = 18363379.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / Glycosides; 0 / Hydroxybenzoates; 0 / Phenols; 120634-86-8 / KS 501
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48. Buschbeck J, Opahle I, Richter M, Rössler UK, Klaer P, Kallmayer M, Elmers HJ, Jakob G, Schultz L, Fähler S: Full tunability of strain along the fcc-bcc bain path in epitaxial films and consequences for magnetic properties. Phys Rev Lett; 2009 Nov 20;103(21):216101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Full tunability of strain along the fcc-bcc bain path in epitaxial films and consequences for magnetic properties.
  • Strained coherent growth on various substrates allows us to adjust the tetragonal distortion from c/a{bct}=1.09 to 1.39, covering most of the Bain transformation path from fcc to bcc crystal structure.

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  • (PMID = 20366053.001).
  • [ISSN] 1079-7114
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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49. Pérez-Prado MT, Zhilyaev AP: First experimental observation of shear induced hcp to bcc transformation in pure Zr. Phys Rev Lett; 2009 May 1;102(17):175504
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First experimental observation of shear induced hcp to bcc transformation in pure Zr.
  • Shear stresses are shown to induce the alpha (hcp) to omega (simple hexagonal) plus beta (bcc) transformation in pure Zr at room temperature.
  • This experimental observation provides new insights about the physical processes underlying allotropic transformations and opens the door to future investigations aiming to stabilize high temperature or pressure phases at ambient conditions.

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  • (PMID = 19518794.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Hernández ER, Rodriguez-Prieto A, Bergara A, Alfè D: First-principles simulations of lithium melting: stability of the bcc phase close to melting. Phys Rev Lett; 2010 May 7;104(18):185701
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First-principles simulations of lithium melting: stability of the bcc phase close to melting.
  • We find excellent agreement with existing experimental data at low pressures, and confirm that above 10 GPa the melting line develops a negative slope, in parallel to what occurs for Na at 30 GPa.
  • Surprisingly, our results indicate that the melting temperature of the bcc phase is always higher than that of fcc Li, suggesting the intriguing possibility of the existence of a narrow field of bcc stability separating the fcc and liquid phases, as predicted by Alexander and McTague [Phys. Rev. Lett.

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  • (PMID = 20482189.001).
  • [ISSN] 1079-7114
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Berkaew P, Soonthornchareonnon N, Salasawadee K, Chanthaket R, Isaka M: Aurocitrin and related polyketide metabolites from the wood-decay fungus Hypocrea sp. BCC 14122. J Nat Prod; 2008 May;71(5):902-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aurocitrin and related polyketide metabolites from the wood-decay fungus Hypocrea sp. BCC 14122.
  • The known gentisaldehyde antibiotic aurocitrin (1), its cis-olefinic isomer (2), a salicylaldehyde analogue (3), two new benzofuran derivatives (4 and 5), and a new dihydroisocoumarin (6) were isolated from the wood-decay fungus Hypocrea sp. BCC 14122.
  • [MeSH-minor] Animals. Candida albicans / drug effects. Cercopithecus aethiops. Drug Screening Assays, Antitumor. Humans. KB Cells. Microbial Sensitivity Tests. Molecular Structure. Mycobacterium tuberculosis / drug effects. Nuclear Magnetic Resonance, Biomolecular. Plasmodium falciparum / drug effects. Staphylococcus aureus / drug effects. Stereoisomerism. Vero Cells. Wood / microbiology

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  • (PMID = 18380478.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aldehydes; 0 / Antimalarials; 0 / Antineoplastic Agents; 0 / Benzofurans; 0 / Coumarins; 0 / aurocitrin
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52. Isaka M, Chinthanom P, Boonruangprapa T, Rungjindamai N, Pinruan U: Eremophilane-type sesquiterpenes from the fungus Xylaria sp. BCC 21097. J Nat Prod; 2010 Apr 23;73(4):683-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eremophilane-type sesquiterpenes from the fungus Xylaria sp. BCC 21097.
  • Seven new eremophilane-type sesquiterpenoids (1-5, 7, and 8) and the known mairetolide F (6) were isolated from the endophytic Xylaria sp. BCC 21097.
  • [MeSH-minor] Animals. Candida albicans / drug effects. Cercopithecus aethiops. Drug Resistance, Multiple / drug effects. Drug Screening Assays, Antitumor. Female. Humans. KB Cells. Microbial Sensitivity Tests. Molecular Structure. Mycobacterium tuberculosis / drug effects. Nuclear Magnetic Resonance, Biomolecular. Plasmodium falciparum / drug effects. Structure-Activity Relationship. Thailand. Vero Cells

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  • (PMID = 20155932.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Sesquiterpenes
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53. Rukachaisirikul V, Chantaruk S, Pongcharoen W, Isaka M, Lapanun S: Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424. J Nat Prod; 2006 Jun;69(6):980-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424.
  • BCC 2424 along with known (2E,6S)-2,6-dimethyl-2,7-octadiene-1,6-diol.
  • [MeSH-minor] Microbial Sensitivity Tests. Molecular Structure. Nuclear Magnetic Resonance, Biomolecular. Thailand

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  • (PMID = 16792425.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents; 0 / Chromones
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54. Kornsakulkarn J, Thongpanchang C, Lapanun S, Srichomthong K: Isocoumarin glucosides from the scale insect fungus Torrubiella tenuis BCC 12732. J Nat Prod; 2009 Jul;72(7):1341-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isocoumarin glucosides from the scale insect fungus Torrubiella tenuis BCC 12732.
  • Three new isocoumarin glucosides (1, 3, and 4), 6,8-dihydroxy-3-methylisocoumarin (2), and 6,8-dihydroxy-3-hydroxymethylisocoumarin (5) were isolated from the scale insect pathogenic fungus Torrubiella tenuis BCC 12732.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Herpesvirus 1, Human / drug effects. Humans. Microbial Sensitivity Tests. Molecular Structure. Mycobacterium tuberculosis / drug effects. Plasmodium falciparum / drug effects

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  • (PMID = 19456117.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents; 0 / Antiviral Agents; 0 / Glucosides; 0 / Isocoumarins
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55. Medvedeva NI, Gornostyrev YN, Freeman AJ: Electronic origin of solid solution softening in bcc molybdenum alloys. Phys Rev Lett; 2005 Apr 8;94(13):136402
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Electronic origin of solid solution softening in bcc molybdenum alloys.
  • The intrinsic mechanism of solid solution softening in bcc molybdenum alloys due to 5d transition metal additions is investigated on the basis of ab initio electronic-structure calculations that model the effect of alloying elements on the generalized stacking fault (GSF) energies.
  • We demonstrate that additions with an excess of electrons (Re, Os, Ir, and Pt) lead to a decrease in the GSF energy and those with a lack of electrons (Hf and Ta) to its sharp increase.

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  • (PMID = 15904008.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Kishikawa J, Kabashima Y, Kurokawa T, Sakamoto J: The cytochrome bcc-aa3-type respiratory chain of Rhodococcus rhodochrous. J Biosci Bioeng; 2010 Jul;110(1):42-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The cytochrome bcc-aa3-type respiratory chain of Rhodococcus rhodochrous.
  • In this work, the respiratory chain of this aerobic organism was investigated and characterized.
  • Grown under highly aerobic conditions, the membrane fraction of R. rhodochrous cells only contained a-, b- and c-type cytochromes, suggesting that it is the cytochrome bcc-aa(3)-type pathway that mainly operates under these conditions.
  • In contrast, the d-type cytochrome was also present under microaerobic conditions, indicating that the alternative pathway of the bd-type oxidase works in these circumstances.
  • [MeSH-major] Electron Transport Complex IV / metabolism. Rhodococcus / enzymology
  • [MeSH-minor] Aerobiosis / physiology. Cell Membrane / chemistry. Cytochrome c Group / metabolism. Cytochrome d Group / metabolism. Cytochromes / analysis. Cytochromes / metabolism. Electron Transport / physiology. Energy Metabolism / physiology. Enzyme Inhibitors / pharmacology. Hydrogen-Ion Concentration. Oxidation-Reduction. Oxidoreductases / metabolism. Oxygen / metabolism

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  • [Copyright] 2009 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20541114.001).
  • [ISSN] 1347-4421
  • [Journal-full-title] Journal of bioscience and bioengineering
  • [ISO-abbreviation] J. Biosci. Bioeng.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Cytochrome c Group; 0 / Cytochromes; 0 / Enzyme Inhibitors; 9035-36-3 / Cytochrome d Group; EC 1.- / Oxidoreductases; EC 1.9.3.1 / Electron Transport Complex IV; S88TT14065 / Oxygen
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57. Landa A, Söderlind P, Ruban AV, Peil OE, Vitos L: Stability in bcc transition metals: Madelung and band-energy effects due to alloying. Phys Rev Lett; 2009 Dec 4;103(23):235501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stability in bcc transition metals: Madelung and band-energy effects due to alloying.
  • The phase stability of group VB (V, Nb, and Ta) transition metals is explored by first-principles electronic-structure calculations.
  • Alloying with a small amount of a neighboring metal can either stabilize or destabilize the body-centered-cubic phase relative to low-symmetry rhombohedral phases.
  • We show that band-structure effects determine phase stability when a particular group VB metal is alloyed with its nearest neighbors within the same d-transition series.
  • In this case, the neighbor with less (to the left) and more (to the right) d electrons destabilize and stabilize bcc, respectively.
  • When alloying with neighbors of higher d-transition series, electrostatic Madelung energy dominates and stabilizes the body-centered-cubic phase.

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  • (PMID = 20366157.001).
  • [ISSN] 1079-7114
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Rawlins J, Platt A, Gowda P: Regression of BCC following immunosuppression withdrawal in a renal transplant recipient. Clin Exp Dermatol; 2006 Sep;31(5):717-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regression of BCC following immunosuppression withdrawal in a renal transplant recipient.
  • [MeSH-major] Carcinoma, Basal Cell / etiology. Immunosuppressive Agents / adverse effects. Kidney Transplantation. Nose Neoplasms / etiology. Tacrolimus / adverse effects
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Regression, Spontaneous

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  • (PMID = 16901322.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; WM0HAQ4WNM / Tacrolimus
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59. Isaka M, Palasarn S, Rachtawee P, Vimuttipong S, Kongsaeree P: Unique diketopiperazine dimers from the insect pathogenic fungus Verticillium hemipterigenum BCC 1449. Org Lett; 2005 May 26;7(11):2257-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unique diketopiperazine dimers from the insect pathogenic fungus Verticillium hemipterigenum BCC 1449.
  • [structure: see text].
  • Vertihemiptellides A (1) and B (2), unique diketopiperazine dimers, were isolated from the insect pathogenic fungus Verticillium hemipterigenum BCC 1449.
  • [MeSH-minor] Animals. Candida albicans / drug effects. Crystallography, X-Ray. Diketopiperazines. Drug Screening Assays, Antitumor. Humans. Inhibitory Concentration 50. Insects. Molecular Conformation. Molecular Structure. Mycobacterium tuberculosis / growth & development. Nuclear Magnetic Resonance, Biomolecular. Plasmodium falciparum / drug effects. Stereoisomerism. Tumor Cells, Cultured

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  • (PMID = 15901183.001).
  • [ISSN] 1523-7060
  • [Journal-full-title] Organic letters
  • [ISO-abbreviation] Org. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antineoplastic Agents; 0 / Diketopiperazines; 0 / Piperazines; 0 / vertihemiptellide A; 0 / vertihemiptellide B
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60. Bunyapaiboonsri T, Yoiprommarat S, Srikitikulchai P, Srichomthong K, Lumyong S: Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789. J Nat Prod; 2010 Jan;73(1):55-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789.
  • Six new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4alpha-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789.
  • Compound 7 showed anti-HSV-1 activity (IC50=14 microM) and cytotoxic activities against KB, BC, NCI-H187, and nonmalignant (Vero) cell lines with respective IC50 values of 37, 26, 32, and 60 microM.
  • Cytotoxic activity against the BC cell line was also observed for compound 6, with an IC50 value of 48 microM.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Herpesvirus 1, Human / drug effects. Humans. Inhibitory Concentration 50. KB Cells. Molecular Structure. Musa / microbiology. Stereoisomerism. Thailand. Vero Cells

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  • (PMID = 20038128.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / Heterocyclic Compounds, 3-Ring
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61. Prathumpai W, Kocharin K, Phimmakong K, Wongsa P: Effects of different carbon and nitrogen sources on naphthoquinone production of Cordyceps unilateralis BCC 1869. Appl Biochem Biotechnol; 2007 Feb;136(2):223-32
Hazardous Substances Data Bank. Nitrogen, Elemental .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of different carbon and nitrogen sources on naphthoquinone production of Cordyceps unilateralis BCC 1869.
  • The production of six naphthoquinone derivatives, erythrostominone, deoxyerythrostominone, 4-O-methyl erythrostominone, epierythrostominol, deoxyerythrostominol, and 3,5,8-trihydroxy-6-methoxy-2-(5-oxohexa- 1,3-dienyl)-1,4-naphthoquinone, was examined during the growth of Cordyceps unilateralis BCC 1869 on different carbon and nitrogen sources.
  • The highest growth rate was obtained on arabinose (0.043 h-1), whereas the maximum overall naphthoquinone concentration was obtained on lactose (2 g/L) at 237 h.

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  • (PMID = 17496342.001).
  • [ISSN] 0273-2289
  • [Journal-full-title] Applied biochemistry and biotechnology
  • [ISO-abbreviation] Appl. Biochem. Biotechnol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Naphthoquinones; 0 / Pigments, Biological; 7440-44-0 / Carbon; N762921K75 / Nitrogen
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62. Sha X, Cohen RE: Finite-temperature magnetism in bcc Fe under compression. J Phys Condens Matter; 2010 Sep 22;22(37):372201
Hazardous Substances Data Bank. IRON, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Finite-temperature magnetism in bcc Fe under compression.
  • We investigate the contributions of finite-temperature magnetic fluctuations to the thermodynamic properties of bcc Fe as functions of pressure.

  • MedlinePlus Health Information. consumer health - Iron.
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  • (PMID = 21403188.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ferric Compounds; 1317-54-0 / ferrite; E1UOL152H7 / Iron
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63. Thongtan J, Saenboonrueng J, Rachtawee P, Isaka M: An antimalarial tetrapeptide from the entomopathogenic fungus Hirsutella sp. BCC 1528. J Nat Prod; 2006 Apr;69(4):713-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An antimalarial tetrapeptide from the entomopathogenic fungus Hirsutella sp. BCC 1528.
  • Hirsutellic acid A (1), a new linear tetrapeptide possessing an anthranilic acid residue at the C-terminus, was isolated from a fermentation broth of the entomopathogenic fungus Hirsutella sp. BCC 1528.
  • The structure of this compound was elucidated by NMR and MS analyses, and its absolute configuration was deduced by HPLC analysis of the acid hydrolysate using a chiral column.
  • Hirsutellic acid A exhibits activity against the malarial parasite Plasmodium falciparum K1 with an IC(50) value of 8.0 microM, while it was noncytotoxic to Vero cells at a concentration of 95 microM.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Molecular Structure. Vero Cells

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  • (PMID = 16643062.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Oligopeptides; 0 / hirsutellic acid A
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64. Jendelová P, Herynek V, Urdziková L, Glogarová K, Rahmatová Š, Fales I, Andersson B, Procházka P, Zamečník J, Eckschlager T, Kobylka P, Hájek M, Sykova E: Magnetic Resonance Tracking of Human CD34 Progenitor Cells Separated by Means of Immunomagnetic Selection and Transplanted into Injured Rat Brain. Cell Transplant; 2005 Apr;14(4):173-182

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We studied whether superparamagnetic nanoparticles (CD34 microbeads), used clinically for specific magnetic sorting, can be used as a magnetic cell label for in vivo cell visualization.
  • Prussian blue and anti-human nuclei staining confirmed the presence of magnetically labeled human cells in the corpus callosum and in the lesion 4 weeks after grafting.
  • Our results show that CD34 microbeads superparamagnetic nanoparticles can be used as a magnetic cell label for in vivo cell visualization.
  • The fact that microbeads coated with different commercially available antibodies can bind to specific cell types opens extensive possibilities for cell tracking in vivo.

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  • (PMID = 28876089.001).
  • [ISSN] 1555-3892
  • [Journal-full-title] Cell transplantation
  • [ISO-abbreviation] Cell Transplant
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cell transplantation / Contrast agents / Hematopoietic stem cells / Magnetic resonance / Migration / Photochemical lesion
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65. Wang BT, Shao JL, Zhang GC, Li WD, Zhang P: Nucleation of hcp and fcc phases in bcc iron under uniform compression: classical molecular dynamics simulations. J Phys Condens Matter; 2010 Nov 3;22(43):435404
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nucleation of hcp and fcc phases in bcc iron under uniform compression: classical molecular dynamics simulations.
  • By classical molecular dynamics simulations employing an embedded atom method potential, we have simulated the bcc to hcp/fcc structural transition in single-crystal iron under uniform compression.
  • The nucleation planes, all belonging to the {110}(bcc) family and parallel to the three compression directions [100], [010], and [001], have been observed.
  • About 20% bcc atoms have transformed to fcc phase under pressure just over the critical point, and under higher pressure the fraction of the fcc phase increases steadily to exceed that of the hcp phase.
  • We have investigated the transition mechanism of iron from initial bcc to hcp/fcc and found that the transition mainly consists of compression, rotation, and shuffle.

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  • (PMID = 21403328.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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66. Hao X, Liu Y, Hui R, Zhang J: Comparison of the sensitivity to endocrine therapy of PR+/ER- patients and ER+/PR- patients with HER2+ breast cancer. J Clin Oncol; 2009 May 20;27(15_suppl):e11558

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of the sensitivity to endocrine therapy of PR+/ER- patients and ER+/PR- patients with HER2+ breast cancer.
  • : e11558 Background: Her2 and PR expression are important indicators for prognosis of breast cancer.
  • METHODS: Collected 3,677 primary breast cancer cases from 2002 to 2004 in Tianjin University Cancer Hospital.
  • All of the cases were confirmed by pathohistological method.
  • With Her2+ breast cancer, 168 patients are PR+/ER- and 211 patients are ER+/PR-.
  • With Her2+ BC, 3-year DFS(disease-free survival rate) of PR+/ER- patients is 94.53%, higher than that of PR-/ER+ ones (91.81%).With Her2- BC, 3-year DFS of PR+/ER- patients is lower than that of PR-/ER+ (p<0.05).
  • 3. Total of 1853 cases with 5-year followed up, and 1297 cases have been given endocrine therapy.
  • CONCLUSIONS: With Her2+ breast cancer, 3-year DFS of PR+/ER- patients is higher than ER+/PR- and also PR+/ER- patients may more sensitive to endocrine therapy than ER+/PR- patients.

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  • (PMID = 27964105.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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67. Pinto Pereira SM, Hipwell JH, McCormack VA, Tanner C, Moss SM, Wilkinson LS, Khoo LAL, Pagliari C, Skippage PL, Kliger CJ, Hawkes DJ, Dos Santos Silva IM: Automated registration of diagnostic to prediagnostic x-ray mammograms: Evaluation and comparison to radiologists' accuracy. Med Phys; 2010 Sep;37(9):4530-4539

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: X-ray mammograms were simulated from MRIs of 20 women using finite element methods for modeling breast compressions and employing a MRI/x-ray appearance change model.
  • Five mammography film readers independently identified landmarks (tumor, nipple, and usually two other normal features) on pairs of diagnostic and corresponding prediagnostic digitized images from 52 breast cancer cases.
  • Registration accuracy was sensitive to the type of landmark and the amount of breast density.

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  • [Copyright] © 2010 American Association of Physicists in Medicine.
  • (PMID = 28524565.001).
  • [ISSN] 2473-4209
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cancer / Digital mammography / Film mammography / Finite element calculations / Image analysis / MRI / Magnetic resonance imaging / Mammography / Medical X-ray imaging / Medical imaging / Radiography / Registration / Tissues / X-ray imaging / affine transforms / biological organs / biomedical MRI / breast cancer / cancer / diagnostic radiography / finite element analysis / image registration / mammographic density / mammography / medical image processing / registration algorithms / tumours
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68. Wafa T: Contribution of BRCA1 and BRCA2 mutations to breast cancer in Tunisia. J Clin Oncol; 2009 May 20;27(15_suppl):e22191

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Contribution of BRCA1 and BRCA2 mutations to breast cancer in Tunisia.
  • : e22191 Background: Hereditary breast cancer accounts for 3-8% of all breast cancers.
  • It was recently estimated that a combination of BRCA1 and BRCA2 genes mutations is responsible for 30% of hereditary breast cancer cases.
  • METHODS: To investigate the prevalence of BRCA1 and BRCA2 gene mutations in breast cancer patients with affected relatives in Tunisia, 36 patients who had at least one first degree relative affected with breast and/or ovarian cancer were analysed.
  • Nineteen percent (7/36) of the familial cases were altered on BRCA1 or BRCA2 genes with deleterious mutations at heterozygous state and 55% (20/36) by mutation with uncertain value (UV) or by single nucleotide polymorphisms (SNPs).
  • CONCLUSIONS: Almost all the cases mutated by deleterious mutations on BRCA1 gene reported a family history of breast and/or ovarian cancer in the index case or in their relatives.
  • On the contrary, patients with an UV mutation or SNPs have no history of ovarian cancer in their corresponding families.

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  • (PMID = 27963625.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Wang X, Li Y, Cao X: False-positive diagnosis of breast cancer by diffused optical tomography with ultrasound. J Clin Oncol; 2009 May 20;27(15_suppl):e22085

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] False-positive diagnosis of breast cancer by diffused optical tomography with ultrasound.
  • : e22085 Background: Breast cancer is one of the most common cancer in women.
  • Early detection, early diagnosis and early treatment play key role in fighting against breast cancer.
  • It provides dual modality images for early diagnosis of breast cancer.
  • The aim of this study was to evaluate the OPTIMUS system on diagnosis of breast disease.
  • METHODS: OPTIMUS system was applied to 160 breast tumor patients.
  • All patients had received surgical treatment and had definite pathological diagnosis.
  • OPTIMUS system was evaluated as diagnostic tool of breast tumor in this study.
  • RESULTS: There were 42 cases diagnosed as benign breast disease and 118 cases diagnosed as breast cancer by OPTIMUS system.
  • Pathology confirmed 60 cases of benign disease and 100 cases of breast cancer.
  • False positive rate of breast cancer was 30% (18/60).
  • False negative rate of breast cancer was 0% (0/100).
  • The pathology of false positive cases was mild and severe papillomatosis (6/18), non-typical hyperplasia (4/18), chronic inflammation (3/18), fibroadenoma (3/18) and fat necrosis (2/18).
  • Papillomatosis and non-typical hyperplasia are precancerous lesions and often difficult for clinical diagnosis.
  • CONCLUSIONS: OPTIMUS system is a non- invasive and highly effective diagnostic tool for breast disease.
  • Its sensitivity is reached to 100% and specificity is about 70% on the diagnosis of breast cancer.
  • OPTIMUS system could be used as assistant diagnostic tool for breast tumor.

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  • (PMID = 27963263.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Mullen T, Markey K, Murphy P, McClean S, Callaghan M: Role of lipase in Burkholderia cepacia complex (Bcc) invasion of lung epithelial cells. Eur J Clin Microbiol Infect Dis; 2007 Dec;26(12):869-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of lipase in Burkholderia cepacia complex (Bcc) invasion of lung epithelial cells.
  • The Burkholderia cepacia complex (Bcc) is a group of ten closely related species associated with life-threatening infection in cystic fibrosis (CF).
  • The Bcc organisms produce a range of exoproducts with virulence potential, including exopolysaccharide, proteases and lipases.
  • Many members of the Bcc are also capable of epithelial cell invasion, although the mechanism(s) involved are poorly understood.
  • This study investigates a role for Bcc lipase in epithelial cell invasion by Bcc strains.
  • Lipase activity was measured in eight species of the Bcc.
  • Strains that produced high levels of lipase were predominantly from the B. multivorans and B. cenocepacia species.
  • Pre-treatment of two epithelial cell lines with Bcc lipase significantly increased invasion by two B. multivorans strains and one B. cenocepacia strain and did not affect either plasma membrane or tight junction integrity.
  • Inhibition of Bcc lipase production by the lipase inhibitor Orlistat significantly decreased invasion by both B. multivorans and B. cenocepacia strains in a concentration-dependent manner.
  • This study demonstrates the extent of lipase production across the Bcc and establishes a potential role for lipase in Bcc epithelial cell invasion.
  • [MeSH-major] Bronchi / cytology. Burkholderia cepacia complex / enzymology. Epithelial Cells / microbiology. Lipase / metabolism
  • [MeSH-minor] Cell Line. Cell Membrane / metabolism. Enzyme Inhibitors / pharmacology. Humans. Lactones / pharmacology. Tight Junctions / metabolism

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  • (PMID = 17874328.001).
  • [ISSN] 0934-9723
  • [Journal-full-title] European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
  • [ISO-abbreviation] Eur. J. Clin. Microbiol. Infect. Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Lactones; 95M8R751W8 / orlistat; EC 3.1.1.3 / Lipase
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71. Bunyapaiboonsri T, Yoiprommarat S, Intereya K, Rachtawee P, Hywel-Jones NL, Isaka M: Isariotins E and F, spirocyclic and bicyclic hemiacetals from the entomopathogenic fungus Isaria tenuipes BCC 12625. J Nat Prod; 2009 Apr;72(4):756-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isariotins E and F, spirocyclic and bicyclic hemiacetals from the entomopathogenic fungus Isaria tenuipes BCC 12625.
  • New spirocyclic and bicyclic hemiacetals, isariotins E (1) and F (2), together with TK-57-164A (3) were isolated from the entomopathogenic fungus Isaria tenuipes BCC 12625.
  • Isariotin F (2) exhibited activity against the malaria parasite Plasmodium falciparum K1 with an IC(50) value of 5.1 microM and cytotoxic activities against cancer cell lines (KB, BC, and NCI-H187) and nonmalignant (Vero) cells with respective IC(50) values of 15.8, 2.4, 1.6, and 2.9 microM.
  • [MeSH-minor] Animals. Antineoplastic Agents / chemistry. Antineoplastic Agents / isolation & purification. Antineoplastic Agents / pharmacology. Candida albicans / drug effects. Cercopithecus aethiops. Drug Screening Assays, Antitumor. Humans. Inhibitory Concentration 50. Molecular Structure. Mycobacterium tuberculosis / drug effects. Parasitic Sensitivity Tests. Thailand. Vero Cells

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  • (PMID = 19265430.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Antineoplastic Agents; 0 / Antitubercular Agents; 0 / Bicyclo Compounds, Heterocyclic; 0 / Epoxy Compounds; 0 / Heterocyclic Compounds, Bridged-Ring; 0 / Spiro Compounds; 0 / TK-57-164A; 0 / isariotin E; 0 / isariotin F
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72. Isaka M, Boonkhao B, Rachtawee P, Auncharoen P: A xanthocillin-like alkaloid from the insect pathogenic fungus Cordyceps brunnearubra BCC 1395. J Nat Prod; 2007 Apr;70(4):656-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A xanthocillin-like alkaloid from the insect pathogenic fungus Cordyceps brunnearubra BCC 1395.
  • Cordyformamide (4), the plausible biogenetic precursor of xanthocillin Y2, was isolated from a culture broth of the insect pathogenic fungus Cordyceps brunnearubra BCC 1395.
  • [MeSH-minor] Animals. Humans. Inhibitory Concentration 50. KB Cells. Molecular Structure

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  • (PMID = 17266369.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alkaloids; 0 / Antimalarials; 0 / Butadienes; 0 / Phenols; 0 / cordyformamide; 06Z55VZ40D / xantocillin
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73. Yaakobi B, Boehly TR, Meyerhofer DD, Collins TJ, Remington BA, Allen PG, Pollaine SM, Lorenzana HE, Eggert JH: EXAFS measurement of iron bcc-to-hcp phase transformation in nanosecond-laser shocks. Phys Rev Lett; 2005 Aug 12;95(7):075501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] EXAFS measurement of iron bcc-to-hcp phase transformation in nanosecond-laser shocks.
  • Extended x-ray absorption fine structure (EXAFS) measurements have demonstrated the phase transformation from body-centered-cubic (bcc) to hexagonal-close-packed (hcp) iron due to nanosecond, laser-generated shocks.

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  • (PMID = 16196790.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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74. Resnick B, Bellg AJ, Borrelli B, Defrancesco C, Breger R, Hecht J, Sharp DL, Levesque C, Orwig D, Ernst D, Ogedegbe G, Czajkowski S: Examples of implementation and evaluation of treatment fidelity in the BCC studies: where we are and where we need to go. Ann Behav Med; 2005 Apr;29 Suppl:46-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Examples of implementation and evaluation of treatment fidelity in the BCC studies: where we are and where we need to go.
  • The treatment fidelity workgroup within the Behavior Change Consortium (BCC) developed guidelines to comprehensively evaluate treatment fidelity in behavior change research.
  • This article describes these guidelines and provides examples from four BCC studies as to how these recommended guidelines for fidelity were considered.

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  • (PMID = 15921489.001).
  • [ISSN] 0883-6612
  • [Journal-full-title] Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
  • [ISO-abbreviation] Ann Behav Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Brasie RA, Patel AR, Nouri K: Basal cell carcinoma of the nail unit treated with Mohs micrographic surgery: superficial multicentric BCC with jagged borders--a histopathological hallmark for nail unit BCC. J Drugs Dermatol; 2006 Jul-Aug;5(7):660-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basal cell carcinoma of the nail unit treated with Mohs micrographic surgery: superficial multicentric BCC with jagged borders--a histopathological hallmark for nail unit BCC.
  • We present a case of basal cell carcinoma (BCC) of the nail unit with a special emphasis on superficial multicentric histopathologic type with jagged borders that was treated with Mohs micrographic surgery.
  • Nail unit BCCs may not be as rare as previously believed and jagged borders in the superficial neoplastic buds may be a hallmark for superficial BCCs of the nail unit.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Nail Diseases / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Humans. Microsurgery

  • MedlinePlus Health Information. consumer health - Nail Diseases.
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  • (PMID = 16865873.001).
  • [ISSN] 1545-9616
  • [Journal-full-title] Journal of drugs in dermatology : JDD
  • [ISO-abbreviation] J Drugs Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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76. Merritt BG, Snow SN, Longley BJ: Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic adnexal carcinoma: differentiation by immunohistochemistry and determining the need for Mohs micrographic surgery. Cutis; 2010 May;85(5):254-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic adnexal carcinoma: differentiation by immunohistochemistry and determining the need for Mohs micrographic surgery.
  • Desmoplastic trichoepithelioma (DTE), infiltrative/morpheaform basal cell carcinoma (BCC), and microcystic adnexal carcinoma (MAC) are tumors in this category that may be difficult to differentiate, especially when evaluating thin biopsy specimens.
  • An accurate diagnosis has important clinical implications.
  • While DTE is a benign neoplasm with indolent behavior, infiltrative/morpheaform BCC and MAC can be highly aggressive, leading to substantial local destruction and potential metastasis.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Carcinoma, Skin Appendage / pathology. Mohs Surgery. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Keratin-20. Male. Middle Aged. Staining and Labeling

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
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  • (PMID = 20540416.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-20
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77. Schneider AS, Kaufmann D, Clark BG, Frick CP, Gruber PA, Mönig R, Kraft O, Arzt E: Correlation between critical temperature and strength of small-scale bcc pillars. Phys Rev Lett; 2009 Sep 4;103(10):105501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation between critical temperature and strength of small-scale bcc pillars.
  • Microcompression tests were performed on focused-ion-beam-machined micropillars of several body-centered-cubic metals (W, Mo, Ta, and Nb) at room temperature.
  • The relationship between yield strength and pillar diameter as well as the deformation morphologies were found to correlate with a parameter specific for bcc metals, i.e., the critical temperature T(c).
  • This finding sheds new light on the phenomenon of small-scale plasticity in largely unexplored non-fcc metals.

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  • (PMID = 19792329.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Isaka M, Palasarn S, Kocharin K, Saenboonrueng J: A cytotoxic xanthone dimer from the entomopathogenic fungus Aschersonia sp. BCC 8401. J Nat Prod; 2005 Jun;68(6):945-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A cytotoxic xanthone dimer from the entomopathogenic fungus Aschersonia sp. BCC 8401.
  • Ascherxanthone A (1), a novel symmetrical tetrahydroxanthone dimer, was isolated from the entomopathogenic fungus Aschersonia sp. BCC 8401.
  • The structure of 1 was elucidated by spectroscopic analysis, especially 2D-NMR.
  • Compound 1 exhibited activity against Plasmodium falciparum K1 with an IC(50) value of 0.20 microg/mL, but it also showed cytotoxic activities against Vero cells and three tumor cell lines.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Drug Screening Assays, Antitumor. Inhibitory Concentration 50. Molecular Structure. Plasmodium falciparum / drug effects. Tumor Cells, Cultured. Vero Cells

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  • (PMID = 15974626.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Xanthones; 0 / ascherxanthone A
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79. Degtyareva VF: The fcc-bcc Bain path in In-Sn and related alloys at ambient and high pressure. J Phys Condens Matter; 2009 Mar 4;21(9):095702

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The fcc-bcc Bain path in In-Sn and related alloys at ambient and high pressure.
  • Experimental high-pressure structural studies on an In-Sn alloy containing 8 at.
  • % Sn reveal an isostructural transition of a face-centered tetragonal phase at pressures above 15 GPa with a switch of the axial ratio from c/a>1 to c/a<1.
  •  a transformation between a face-centered cubic (fcc) and a body-centered cubic (bcc) structure.
  • A common Bain path from fcc to bcc is discussed within a nearly-free-electron model of Brillouin-zone-Fermi-sphere interactions.

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  • (PMID = 21817405.001).
  • [ISSN] 0953-8984
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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80. Wang BT, Shao JL, Zhang GC, Li WD, Zhang P: Molecular dynamics simulations of hcp/fcc nucleation and growth in bcc iron driven by uniaxial compression. J Phys Condens Matter; 2009 Dec 2;21(49):495702
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular dynamics simulations of hcp/fcc nucleation and growth in bcc iron driven by uniaxial compression.
  • Molecular dynamics simulations have been performed to study the structural transition in bcc iron under uniaxial strain loading.
  • However, the pressure interval of a mixed phase for [011] loading is much shorter than loading along other orientations.
  • The nucleation and growth of the hcp/fcc phases, and their crystal orientation dependence, were analyzed in detail, where the atom structure was presented by the topological medium-range-order analysis.
  • For [001] compression, the hcp structure occurs first and grows into a laminar morphology in the (011)(bcc) plane with some fcc atoms as an intermediate structure.
  • For loading along [011] and [111] directions, both hcp and fcc structure nucleation and growth along the {110}(bcc) planes are observed; their morphology is also discussed.

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  • (PMID = 21836202.001).
  • [ISSN] 1361-648X
  • [Journal-full-title] Journal of physics. Condensed matter : an Institute of Physics journal
  • [ISO-abbreviation] J Phys Condens Matter
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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81. Barnes EA, Heidtman KJ, Donoghue DJ: Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. Oncogene; 2005 Jan 27;24(5):902-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC.
  • Mutations in the transmembrane receptor patched1 (ptc1) are responsible for the majority of basal cell carcinoma (BCC) cases.
  • Many of these mutations, including ptc1-Q688X, result in premature truncation of the ptc1 protein. ptc1-Q688X has been identified in patients with both BCC and nevoid basal cell carcinoma syndrome, an inheritable disorder causing a predisposition to cancer susceptibility.
  • Cells expressing ptc1-Q688X demonstrate an increase in cell cycle progression and induce cell transformation.
  • [MeSH-major] Carcinoma, Basal Cell / genetics. Membrane Proteins / genetics. Mutation. Trans-Activators / genetics
  • [MeSH-minor] 3T3 Cells. Animals. Cell Division / genetics. Cell Line. Hedgehog Proteins. Humans. Hydroxyurea / pharmacology. Kidney. Mice. Mitosis / drug effects. Mutagenesis, Site-Directed. Receptors, Cell Surface

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  • (PMID = 15592520.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM65490; United States / NCI NIH HHS / CA / P30CA23100-18; United States / NCI NIH HHS / CA / T32-CA09523
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hedgehog Proteins; 0 / Membrane Proteins; 0 / Receptors, Cell Surface; 0 / SHH protein, human; 0 / Trans-Activators; 0 / patched receptors; X6Q56QN5QC / Hydroxyurea
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82. Isaka M, Yangchum A, Rachtawee P, Komwijit S, Lutthisungneon A: Hopane-type triterpenes and binaphthopyrones from the scale insect pathogenic fungus Aschersonia paraphysata BCC 11964. J Nat Prod; 2010 Apr 23;73(4):688-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hopane-type triterpenes and binaphthopyrones from the scale insect pathogenic fungus Aschersonia paraphysata BCC 11964.
  • Two new triterpenes, 17(21)-hopene-6alpha,12beta-diol (1) and 17(21)-hopen-12beta-ol (2), the known 17(21)-hopen-6alpha-ol (zeorinin, 3), and two new biarylic dihydronaphthopyrones, aschernaphthopyrones A (4) and B (5), were isolated from the scale insect pathogenic fungus Aschersonia paraphysata BCC 11964.
  • [MeSH-minor] Animals. Cercopithecus aethiops. Drug Resistance, Multiple / drug effects. Drug Screening Assays, Antitumor. Female. Humans. Inhibitory Concentration 50. Insects / microbiology. KB Cells. Molecular Structure. Thailand. Vero Cells

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  • (PMID = 20364867.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 17(21)-hopen-12beta-ol; 0 / 17(21)-hopene-6alpha,12beta-diol; 0 / Antimalarials; 0 / Naphthalenes; 0 / Pyrones; 0 / Triterpenes; 0 / aschernaphthopyrone A; 0 / aschernaphthopyrone B; 1615-91-4 / diploptene
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83. Tomas S: The 'ultra slow' BCC - two case studies. Aust Fam Physician; 2010 Apr;39(4):227-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The 'ultra slow' BCC - two case studies.
  • Most basal cell carcinomas (BCCs) can be diagnosed readily on the basis of a medical history and clinical examination, particularly when various 'red flags' are taken into account.
  • The purpose of this article is to show two cases in which BCCs have apparently remained unchanged for over 20 years, masking one of the major indicators of malignancy: change.
  • A general practitioner must maintain a high degree of vigilance so as not to miss those BCCs that behave in an atypical manner.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / physiopathology. Disease Progression. Skin Neoplasms / diagnosis

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  • (PMID = 20372683.001).
  • [ISSN] 0300-8495
  • [Journal-full-title] Australian family physician
  • [ISO-abbreviation] Aust Fam Physician
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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84. Isaka M, Palasarn S, Lapanun S, Chanthaket R, Boonyuen N, Lumyong S: Gamma-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199. J Nat Prod; 2009 Sep;72(9):1720-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gamma-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199.
  • Two new gamma-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1alpha,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199.
  • [MeSH-minor] Animals. Candida albicans / drug effects. Cercopithecus aethiops. Diterpenes / isolation & purification. Drug Screening Assays, Antitumor. Humans. Magnaporthe / drug effects. Microbial Sensitivity Tests. Molecular Structure. Mycobacterium tuberculosis / drug effects. Plasmodium falciparum / drug effects. Stereoisomerism. Thailand. Vero Cells

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  • (PMID = 19739600.001).
  • [ISSN] 1520-6025
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Diterpenes; 0 / Furans; 0 / Sesquiterpenes, Eudesmane; 0 / diaporthein B; 0 / ent-4(15)-eudesmen-11-ol-1-one; 0 / ent-4(15)-eudesmen-1alpha,11-diol; 0 / eutypellin A; 0 / eutypellin B
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85. Madla S, Isaka M, Wongsa P: Modification of culture conditions for production of the anti-tubercular hirsutellones by the insect pathogenic fungus Hirsutella nivea BCC 2594. Lett Appl Microbiol; 2008 Aug;47(2):74-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Modification of culture conditions for production of the anti-tubercular hirsutellones by the insect pathogenic fungus Hirsutella nivea BCC 2594.
  • AIMS: This work aimed to improve the production of anti-tubercular hirsutellones by the insect pathogenic fungus Hirsutella nivea BCC 2594.
  • Under the basal conditions, static cultivation at 25 degrees C in minimum salt medium, only hirsutellone B and C were detected with maximum concentrations of 139.00 and 18.27 mg l(-1).
  • As a result, the significant amounts of hirsutellones A-D were obtained with the concentration of 29.93, 169.63, 22.65 and 15.71 mg l(-1) within 15 days.
  • CONCLUSIONS: Improved titres of hirsutellones in H. nivea BCC 2549 were achieved with an agitated (200 rev min(-1)) fructose-peptone medium at 25 degrees C.
  • SIGNIFICANCE AND IMPACT OF THE STUDY: Improved yields of hirsutellones B-D will enable medicinal chemistry modifications leading to a development of a potential candidate for tuberculosis therapy.

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  • (PMID = 18565141.001).
  • [ISSN] 1472-765X
  • [Journal-full-title] Letters in applied microbiology
  • [ISO-abbreviation] Lett. Appl. Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antitubercular Agents; 0 / Culture Media; 0 / Peptones; 30237-26-4 / Fructose; 7440-44-0 / Carbon; IY9XDZ35W2 / Glucose; N762921K75 / Nitrogen; S88TT14065 / Oxygen
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86. Rukachaisirikul V, Tansakul C, Saithong S, Pakawatchai C, Isaka M, Suvannakad R: Hirsutane sesquiterpenes from the fungus Lentinus connatus BCC 8996. J Nat Prod; 2005 Nov;68(11):1674-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hirsutane sesquiterpenes from the fungus Lentinus connatus BCC 8996.
  • Two new hirsutane sesquiterpenes, connatusins A (1) and B (2), were isolated from the fungus Lentinus connatus BCC 8996.
  • An X-ray analysis was performed to confirm the structure of 1.
  • [MeSH-minor] Animals. Crystallography, X-Ray. Drug Screening Assays, Antitumor. Humans. Inhibitory Concentration 50. Molecular Conformation. Molecular Structure. Thailand

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  • (PMID = 16309322.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Antineoplastic Agents; 0 / Sesquiterpenes; 0 / connatusin A; 0 / connatusin B
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87. Paavilainen V, Tuominen J, Aho VV, Saari KM: Long-term results after treatment of basal cell carcinoma of the eyelid in South-Western Finland. Eur J Ophthalmol; 2007 Jul-Aug;17:494-500

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results after treatment of basal cell carcinoma of the eyelid in South-Western Finland.
  • : . PURPOSE: Basal cell carcinoma (BCC) is the most common skin cancer of the eyelid, showing an increasing incidence in the white population.
  • The authors studied the clinical characteristics and the treatment results of BCC of the eyelid in southwestern Finland during 1977-1997.
  • METHODS: The authors reviewed the case records of 191 patients with BCC of the eyelids treated at the Turku University Eye Clinic during 1977-1997.
  • RESULTS: The 191 patients had altogether 194 BCC tumors of the eyelid with the mean diameter of the tumor being smaller than 10 mm in 77.3% of cases.
  • Of the 194 BCC tumors of the eyelid 16.0% showed recurrence, and the recurrence rate of all surgically treated tumors was 13.7%.
  • In this study 61 patients (31.9%) developed other malignancies than the BCC of the eyelid including 28 patients (14.7 %) with carcinoma in other locations than skin.
  • CONCLUSIONS: Incompletely removed BCCs of the eyelid showed only 18.9% recurrence rate during the follow-up time.
  • On the other hand, BCCs of the eyelid should not be underestimated because of the rather high total recurrence rate.
  • The frequency of 31.9% of other malignancies than BCC of the eyelid is remarkably high and requires special attention from the ophthalmologist taking care of the patient with BCC of the eyelid.

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  • (PMID = 28221540.001).
  • [ISSN] 1724-6016
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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88. Xu S, Zhou H, Sun Z, Xie J: Formation of an fcc phase through a bcc metastable state in crystallization of charged colloidal particles. Phys Rev E Stat Nonlin Soft Matter Phys; 2010 Jul;82(1 Pt 1):010401

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Formation of an fcc phase through a bcc metastable state in crystallization of charged colloidal particles.
  • By in situ monitoring structural changes with the reflection spectrometer during the colloidal crystallization, we present direct experimental evidence of liquid-bcc-fcc phase transition in crystallization of charged colloidal particles, as a manifestation of the Ostwald's step rule.
  • In addition, the lifetime of the bcc metastable structure in this system decreases significantly with increasing particle volume fraction, offering a possible explanation for "exceptions" to the step rule.

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  • (PMID = 20866555.001).
  • [ISSN] 1550-2376
  • [Journal-full-title] Physical review. E, Statistical, nonlinear, and soft matter physics
  • [ISO-abbreviation] Phys Rev E Stat Nonlin Soft Matter Phys
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Choi J, Choo J, Chung H, Gweon DG, Park J, Kim HJ, Park S, Oh CH: Direct observation of spectral differences between normal and basal cell carcinoma (BCC) tissues using confocal Raman microscopy. Biopolymers; 2005 Apr 5;77(5):264-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Direct observation of spectral differences between normal and basal cell carcinoma (BCC) tissues using confocal Raman microscopy.
  • Raman spectroscopy has strong potential for providing noninvasive dermatological diagnosis of skin cancer.
  • In this study, confocal Raman microscopy was applied to the dermatological diagnosis for one of the most common skin cancers, basal cell carcinoma (BCC).
  • BCC tissues were obtained from 10 BCC patients using a routine biopsy and used for confocal Raman measurements.
  • Distinct Raman band differences between normal and BCC tissues for the amide I mode and the PO2- symmetric stretching mode showed that this technique has strong potential for use as a dermatological diagnostic tool without the need for statistical treatment of spectral data.
  • It was also possible to precisely differentiate BCC tissue from surrounding noncancerous tissue using the confocal Raman depth profiling technique.
  • We propose that confocal Raman microscopy provides a novel method for dermatological diagnosis since direct observations of spectral differences between normal and BCC tissues are possible.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Skin / cytology. Skin / pathology. Skin Neoplasms / pathology. Spectrum Analysis, Raman

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  • [Copyright] Copyright (c) 2005 Wiley Periodicals, Inc.
  • (PMID = 15657894.001).
  • [ISSN] 0006-3525
  • [Journal-full-title] Biopolymers
  • [ISO-abbreviation] Biopolymers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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90. Rukachaisirikul V, Chantaruk S, Tansakul C, Saithong S, Chaicharernwimonkoon L, Pakawatchai C, Isaka M, Intereya K: A cyclopeptide from the Insect pathogenic fungus Cordyceps sp. BCC 1788. J Nat Prod; 2006 Feb;69(2):305-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A cyclopeptide from the Insect pathogenic fungus Cordyceps sp. BCC 1788.
  • BCC 1788 along with four known bioxanthracenes (2-5).
  • The structure was elucidated by spectroscopic data.
  • [MeSH-minor] Animals. Artemisinins / pharmacology. Beetles. Cercopithecus aethiops. Chromatography, High Pressure Liquid. Crystallography, X-Ray. Inhibitory Concentration 50. Larva. Molecular Structure. Plasmodium falciparum / drug effects. Protein Conformation. Sesquiterpenes / pharmacology. Thailand. Vero Cells

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  • (PMID = 16499340.001).
  • [ISSN] 0163-3864
  • [Journal-full-title] Journal of natural products
  • [ISO-abbreviation] J. Nat. Prod.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Artemisinins; 0 / Peptides, Cyclic; 0 / Sesquiterpenes; 0 / cordyheptapeptide A; 6A9O50735X / dihydroartemisinin
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96. Fury MG, Sherman E, Stambuk H, Haque S, Lisa D, Shen R, Carlson D, Pfister DG: Phase I study of everolimus (E; RAD001) + low-dose weekly cisplatin (C) for patients with advanced solid tumors: Preliminary results. J Clin Oncol; 2009 May 20;27(15_suppl):e14527

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Patients received E per oral for days 1-21 of a 28 day cycle.
  • At DL1, 3 patients were inevaluable (1 withdrawal of consent prior to treatment, 1 disease progression during cycle 1, 1 recurrent diverticulitis during cycle 1) and were replaced.
  • Minor response seen in pulmonary carcinoid (n = 1); prolonged SD ≥ 6 cycles seen in pulmonary carcinoid (n=2), basal cell carcinoma (n=1), and esthesioneuroblastoma (n=1).

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  • (PMID = 27963576.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Gorin MA, Iniesta MD, Douglas JA, Milliron KJ, Merajver SD: Absence of the CHEK2*1100delC mutation in non-BRCA1/2 families with multiple cancer types in a high-risk clinic population of Caucasian ancestry. J Clin Oncol; 2009 May 20;27(15_suppl):11040

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Absence of the CHEK2*1100delC mutation in non-BRCA1/2 families with multiple cancer types in a high-risk clinic population of Caucasian ancestry.
  • : 11040 Background: Checkpoint kinase 2(CHEK2) is a cell-cycle-checkpoint kinase that phosphorylates p53 and BRCA1 in response to DNA damage.
  • The contribution of CHEK2 mutations to familial cancer has been widely studied in breast cancer.
  • Most notably, the CHEK2*1100delC mutation has been characterized to confer a 2-fold increased risk for breast cancer in carriers.
  • This finding comes from studies performed on Northern and Eastern European populations.
  • In contrast to the work done in Europe, these studies suggest a lower frequency of CHEK2*1100delC mutations in breast cancer families.
  • The aim of this study was to determine the frequency of CHEK2*1100delC in members of breast cancer families who tested negative for a deleterious mutation in BRCA1/2.
  • Families were characterized by the presence of several cases of breast and/or ovarian cancer and multiple members with other cancers in a single lineage.
  • RESULTS: No CHEK2*1100delC mutations were detected in 115 individuals, including 39 women diagnosed with breast cancer at an early age, 7 women with bilateral cancer, 2 men with breast cancer and 6 women with ovarian cancer, all of whom were negative for mutations in BRCA1/2.The CHEK2 Breast Cancer Consortium previously reported a frequency of 2.3% for the CHEK2*1100delC mutation among breast cancer cases from families with at least 2 cases of breast cancer (or breast and ovarian cancer) in a first- or second-degree relationship.
  • CONCLUSIONS: Our data are consistent with previous reports that suggest a lower frequency of CHEK2*1100delC mutations in North American hereditary breast cancer families without BRCA1/2 mutations and enriched for multiple cancer types.
  • The low frequency of the CHEK2*1100delC in the North American population limits its clinical relevance as a cancer predisposing gene.

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  • (PMID = 27963982.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Olsson H, Attner B, Noreen D, Lithman T: Comorbidity prior to diagnosis in patients with common cancer diagnoses. J Clin Oncol; 2009 May 20;27(15_suppl):e22180

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comorbidity prior to diagnosis in patients with common cancer diagnoses.
  • : e22180 Background: Chronic disease as diabetes, hypertonia and anemia may be associated with cancer risk as well as affect the short term survival of the malignancy.
  • METHODS: Using population based registry data from specialist and primary care in our health care region comorbidity in the form of anemia, hypertonia, diabetes, rheumatoid arthritis, chronic obstructive pulmonary diasease (KOL), and alcohol related diseases for patients with colon-, rectal-, lung-, prostate and breast cancer and survival were studied.
  • Altogether 2047 colon cancer cases, 985 rectal cancer cases, 2017 lung cancer cases, 3578 breast cancer cases and 5106 prostate cancer cases diagnosed 2000-2005 were included.
  • Comorbidity was studied prior to cancer diagnosis and in order to compare with the general population all first comorbidity diagnoses within 90 days were censored.
  • Patients with colon and rectal cancer had a higher prevalence of anemia, and diabetes.
  • Patients with lung cancer had a higher prevalence of anemia, KOL, diabetes, rheumatoid arthritis for both men and women and for men also a higher prevalence of alcohol related diseases.
  • Except for alcohol related diseases in females with breast cancer comorbidity for the above diseases was not significantly elevated for breast or prostate cancer.
  • Survival of the different cancer diagnoses was not significantly related to the comorbidity except for a tendency of worse survival for patients with alcohol related disease.
  • CONCLUSIONS: The prevalence of some common chronic diseases are elevated especially in colon-, rectal and lung cancer patients.
  • The comorbidity does not seem to affect short term survival of the cancer patient except for alcohol related diagnoses.
  • Our study also indicates the necessity to have all levels of care included in the study base of comorbidity and also emphasizes the need to censor time prior to diagnosis when comparing data with the general population.

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  • (PMID = 27963595.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Iturbe J Jr, Zwenger A, Lacava JA, Perez Verdera P, Vallejo C, Romero A, Leone JP, Perez J, Maccihavelli M, Leone B: Treatment of early breast cancer (EBC): A long-term follow-up study-GOCS experience. J Clin Oncol; 2009 May 20;27(15_suppl):e11610

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of early breast cancer (EBC): A long-term follow-up study-GOCS experience.
  • : e11610 Background: Most cases of breast cancer are diagnosed at early stage of disease, therefore treatment is oriented to increase the relapse-free survival (RFS) and overall survival (OS).
  • RFS was analyzed from the date of initial diagnosis to the date of local or distant recurrence.
  • OS was estimated from the date of initial diagnosis to the last follow-up or date of death.
  • Adjuvant radiation therapy was administered to 73% of pts, whereas adjuvant chemotherapy to 29% and adjuvant hormone therapy to 18.5% of cases.
  • Local recurrence was documented in 37 pts (3.8%) whereas 269 developed metastatic disease (29%).
  • Bilateral breast cancer was seen in 102 cases (10.9%) and 91 pts (9.7%) developed 2nd malignancies.
  • This group of pts continues to have a good prognosis as shown by the OS rate at 5, 10, 15, 20 and 25 years, although high percentage of pts continue to have recurrence and die from breast cancer after 5, 10, 15, 20 and 25 years of follow-up.

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  • (PMID = 27961127.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Miao GX, Ramos AV, Moodera JS: Infinite magnetoresistance from the spin dependent proximity effect in symmetry driven bcc-Fe/V/Fe heteroepitaxial superconducting spin valves. Phys Rev Lett; 2008 Sep 26;101(13):137001

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infinite magnetoresistance from the spin dependent proximity effect in symmetry driven bcc-Fe/V/Fe heteroepitaxial superconducting spin valves.
  • Superconductivity in fully epitaxial bcc-Fe/V/Fe hybrid spin valve structures is influenced by the spin currents and supercurrents as well as band symmetry.

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  • (PMID = 18851482.001).
  • [ISSN] 0031-9007
  • [Journal-full-title] Physical review letters
  • [ISO-abbreviation] Phys. Rev. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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