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Items 1 to 9 of about 9
1. Herzog Neto G, Sebastiá R, Viana GA, Machado F: [Eyelid reconstruction with Fricke's flap: report of two cases]. Arq Bras Oftalmol; 2006 Jan-Feb;69(1):123-6
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  • [Title] [Eyelid reconstruction with Fricke's flap: report of two cases].
  • [Transliterated title] Reconstrução palpebral com retalho de Fricke: relato de dois casos.
  • Skin cancer is the most common neoplasm in human beings and among them, basal cell carcinoma is the most prevalent.
  • This report shows two cases with this tumor, located in the lateral canthus, affecting both the superior and inferior eyelids.
  • The CT scan revealed that the tumor had compromised about 80% of the left superior eyelid, 70% of the inferior eyelid and showed superficial invasion of the lateral orbital wall.
  • The histopathological test diagnosed basal cell carcinoma, with clear margins.
  • The reconstruction of both eyelids was done with Fricke's flap.
  • The second patient was a female, 68 years old, who had an accident with multiple scars at the left side of her face two years before.
  • The CT scan showed that the tumor had affected about 90% of the left superior eyelid, 65% of the inferior eyelid and showed superficial invasion of the lateral orbital wall.
  • The histopathological test diagnosed basal cell carcinoma, with clear margins.
  • The reconstruction of both eyelids was done with Fricke's flap.
  • The authors believe that although this flap is not the first choice for a reconstructive procedure, it should not be forgotten because in some patients, it would be the only possible choice.
  • [MeSH-major] Blepharoplasty / methods. Carcinoma, Basal Cell / surgery. Eyelid Neoplasms / surgery. Skin Neoplasms / surgery. Surgical Flaps

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  • (PMID = 16491248.001).
  • [ISSN] 0004-2749
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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2. Adenis JP, Izambart C: [Suspicious eyelid spots]. J Fr Ophtalmol; 2010 Feb;33(2):122-4
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  • [Title] [Suspicious eyelid spots].
  • Flat lesions of the eyelids are in most cases related to precancerous skin lesions or malignant tumors of the eyelids.
  • Rarely, the following diagnoses can be established: alkaptonuria, Addison disease, argyrosis, or toxicity to systemic medications.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Addison Disease / diagnosis. Alkaptonuria / diagnosis. Argyria / diagnosis. Biopsy. Bowen's Disease / diagnosis. Carcinoma, Basal Cell / diagnosis. Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Humans. Keratosis, Actinic / diagnosis. Melanoma / diagnosis. Neoplasm Staging. Pigmentation. Precancerous Conditions / diagnosis. Prognosis. Radiodermatitis / diagnosis

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  • [Copyright] Copyright (c) 2010. Published by Elsevier Masson SAS.
  • (PMID = 20116885.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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3. Deprez M, Uffer S: Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol; 2009 May;31(3):256-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.
  • Eyelid tumors are the most common neoplasm in daily ophthalmology practice and encompass a wide variety of benign and malignant tumors.
  • In this retrospective study, we report the clinical and histological features of 5504 eyelid skin tumors diagnosed at the Laboratory of Ophthalmopathology of the Hôpital Ophtalmique Jules Gonin, Lausanne, Switzerland, between January 1989 and December 2007.
  • Benign tumors largely predominated over malignant ones, representing 84% of cases in this series, and the 5 most frequent subtypes were squamous cell papilloma (26%), seborrheic keratosis (21%), melanocytic nevus (20%), hidrocystoma (8%), and xanthoma/xanthelasma (6%).
  • Basal cell carcinoma was the most frequent malignant tumor (86%), followed by squamous cell carcinoma (7%) and sebaceous carcinoma (3%).
  • For several tumor subtypes, there was a poor correlation between clinical and histological diagnosis, stressing the numerous pitfalls in the diagnosis of eyelid tumors.
  • [MeSH-major] Eyelid Diseases / pathology. Eyelid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / pathology. Child. Child, Preschool. Female. Hidrocystoma / pathology. Humans. Infant. Keratosis, Seborrheic / pathology. Male. Middle Aged. Nevus, Pigmented / pathology. Papilloma / pathology. Predictive Value of Tests. Retrospective Studies. Sebaceous Gland Neoplasms / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Xanthomatosis / pathology. Young Adult

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  • (PMID = 19384066.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 32
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4. Levin F, Khalil M, McCormick SA, Della Rocca D, Maher E, Della Rocca RC: Excision of periocular basal cell carcinoma with stereoscopic microdissection of surgical margins for frozen-section control: report of 200 cases. Arch Ophthalmol; 2009 Aug;127(8):1011-5
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  • [Title] Excision of periocular basal cell carcinoma with stereoscopic microdissection of surgical margins for frozen-section control: report of 200 cases.
  • OBJECTIVE: To report our experience with 200 cases of basal cell carcinoma (BCC) in 192 patients treated with an enhanced frozen-section control (FSC) technique using stereoscopic microdissection of surgical margins.
  • METHODS: Retrospective series of 192 patients with 200 lesions diagnosed as BCC of the periocular region.
  • All were excised en bloc with 1-mm margins beyond the clinically apparent tumor and examined using an enhanced FSC technique with stereoscopic microdissection of the surgical margins.
  • RESULTS: Of 200 malignant BCCs, 93.0% represented primary tumors.
  • There were no recurrences in the secondary tumor group after a mean follow-up of 4.8 years.
  • Of the 200 lesions, 66.0% lesions required a single en bloc resection to achieve tumor-free margins.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Cryosurgery / methods. Eyelid Neoplasms / surgery. Microsurgery / methods. Ophthalmologic Surgical Procedures. Skin Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Frozen Sections / methods. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Retrospective Studies

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  • (PMID = 19667338.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Chew R: Destruction of the orbit and globe by recurrence of basal cell carcinoma. Optometry; 2007 Jul;78(7):344-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Destruction of the orbit and globe by recurrence of basal cell carcinoma.
  • BACKGROUND: Basal cell carcinoma (BCC) is the most common skin malignancy and represents 90% of eyelid malignancies.
  • Of those that occur on the eyelids, most involve the lower lid.
  • CASE REPORT: The patient described in this case report had basal cell carcinoma of the upper right lid 4 to 5 years prior to examination.
  • At that time the patient was treated with surgical excision and radiotherapy.
  • Subsequently, he had not received any eye care since the initial surgery to remove the malignancy.
  • He had extensive surgery to remove the tumor and subsequent skin grafting.
  • This case underscores the importance of proper follow-up protocol for all surgical patients as well as patient education that reinforces the importance of follow-up care and self-monitoring on the part of the patient.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Eyelid Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Orbit / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Ophthalmologic Surgical Procedures / methods. Tomography, X-Ray Computed

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  • (PMID = 17601572.001).
  • [ISSN] 1529-1839
  • [Journal-full-title] Optometry (St. Louis, Mo.)
  • [ISO-abbreviation] Optometry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Abedalthagafi M, Rushing EJ, Auerbach A, Desouki MM, Marwaha J, Wang Z, Fanburg-Smith JC: Sporadic cutaneous angiosarcomas generally lack hypoxia-inducible factor 1alpha: a histologic and immunohistochemical study of 45 cases. Ann Diagn Pathol; 2010 Feb;14(1):15-22
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  • [Title] Sporadic cutaneous angiosarcomas generally lack hypoxia-inducible factor 1alpha: a histologic and immunohistochemical study of 45 cases.
  • Cutaneous angiosarcoma (AS) is a rare malignant neoplasm of dermis composed of infiltrating cells of endothelial phenotype with overall poor prognosis.
  • Although autocrine stimulation by vascular endothelial growth factor secretion may play a role in the pathogenesis of angiosarcoma, its mechanism has not been fully established.
  • Cases coded as "angiosarcoma" of dermis were culled and re-reviewed for inclusion as AS, based on patient folder, slides, and obtained immunohistochemistry including CD31 and smooth muscle actin (SMA).
  • Tumors presented most commonly in the skin of the scalp followed by the left lower leg, face, nose, lower arm, neck, thigh, eyelid, ear, and temple.
  • Associated basal cell carcinoma was noted in 1 patient; no others had other neoplasms or unrelated surgeries.
  • Epithelioid morphology was present in 29% (n = 13) cases.
  • CD31 highlighted malignant endothelial cells.
  • Treatment and follow-up data were only available on 4 cases: 2 died of disease within 4 years, 2 others had known recurrence within 2 years.
  • Requirement for diagnosis includes extravascular proliferation of atypical endothelial cells with mitotic activity in vasoformative, solid, and papillary patterns.
  • Absence of SMA can prove extravascular extension of tumor, outside their normal vessel confines.
  • Accordingly, the hypoxic response pathway is not thought to be a documentable common mechanism of angiogenesis in this entity.
  • [MeSH-major] Dermis / metabolism. Hemangiosarcoma / metabolism. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Neovascularization, Pathologic / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Anoxia / metabolism. Anoxia / pathology. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local / metabolism. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20123452.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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7. Ntomouchtsis A, Vahtsevanos K, Patrikidou A, Andreadis C, Tsobanidou C, Antoniades K: Adnexal skin carcinomas of the face. J Craniofac Surg; 2009 Jan;20(1):134-7
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  • [Title] Adnexal skin carcinomas of the face.
  • Skin adnexal neoplasms are rare tumors, and knowledge on their exact histological development and pathogenesis remains fragmented.
  • Their diagnosis and management are frequently troublesome, especially for malignant tumors.
  • We present a retrospective case series of malignant appendageal tumors of the face.
  • Records of patients with histologically confirmed adnexal skin carcinoma managed at a single department during the period 1995 to 2004 were reviewed.
  • Patient biodata, surgical management, and main outcome measures such as locoregional recurrence, distant metastasis, and disease-free and overall survival were recorded.Eleven patients were identified from record analysis.
  • Lesions were mainly located at the eyelids and the nose.
  • Nine of 11 patients were alive and free of local and/or regional disease on final follow-up.
  • Two patients died of causes unrelated to the disease.
  • Clinical and histological features, tumor biological behavior, diagnostic difficulties, and recommended management are discussed.In conclusion, adnexal skin tumors should be considered in the differential diagnosis of skin tumors, particularly in view of their more sinister prognosis compared with other nonmelanoma skin tumors.
  • [MeSH-major] Carcinoma, Skin Appendage / surgery. Facial Neoplasms / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / diagnosis. Carcinoma, Squamous Cell / diagnosis. Cohort Studies. Diagnosis, Differential. Disease-Free Survival. Eyelid Neoplasms / surgery. Female. Follow-Up Studies. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Neck Dissection. Neoplasm Recurrence, Local / pathology. Neoplasms, Second Primary / pathology. Nose Neoplasms / surgery. Retrospective Studies. Surgical Flaps. Survival Rate. Treatment Outcome

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  • (PMID = 19165010.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Barbarino S, McCormick SA, Lauer SA, Milman T: Syringocystadenoma papilliferum of the eyelid. Ophthal Plast Reconstr Surg; 2009 May-Jun;25(3):185-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Syringocystadenoma papilliferum of the eyelid.
  • PURPOSE: To describe 6 patients with syringocystadenoma papilliferum of the eyelid and to review the literature regarding this rare eyelid tumor.
  • METHODS: Clinicopathologic series of 6 cases, diagnosed at the New York Eye and Ear Infirmary from 1990 to 2006.
  • The PubMed database was searched for reported cases of syringocystadenoma papilliferum of the eyelid (keywords: syringocystadenoma, eyelid, apocrine, eccrine).
  • RESULTS: Fourteen patients (6 from the current case series and 8 previously reported) with syringocystadenoma papilliferum of the eyelid were identified.
  • Patient age ranged from 8 to 82 years (mean, 44.6 years).
  • Most cases had a preoperative diagnosis of basal cell carcinoma or cyst.
  • Papillary structures with plasma cell-rich stromal infiltrate protruded in the cystic invaginations.
  • None of the lesions was associated with a malignant neoplasm.
  • CONCLUSIONS: Syringocystadenoma papilliferum can rarely affect eyelid skin.
  • This lesion is frequently clinically misdiagnosed as basal cell carcinoma or cyst.
  • Although syringocystadenoma papilliferum of the eyelid can be associated with other benign lesions, no malignant transformation or association with malignant neoplasms has been reported.
  • The evidence suggests that this tumor should be managed with conservative complete excision.
  • [MeSH-major] Cystadenoma / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Dermis / pathology. Epidermis / pathology. Eyelids / pathology. Female. Humans. Male. Middle Aged

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  • (PMID = 19454927.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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9. Gayre GS, Hybarger CP, Mannor G, Meecham W, Delfanti JB, Mizono GS, Guerry TL, Chien JS, Sooy CD, Anooshian R, Simonds R, Pietila KA, Smith DW, Dayhoff DA, Engman E, Lacy J: Outcomes of excision of 1750 eyelid and periocular skin basal cell and squamous cell carcinomas by modified en face frozen section margin-controlled technique. Int Ophthalmol Clin; 2009;49(4):97-110
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  • [Title] Outcomes of excision of 1750 eyelid and periocular skin basal cell and squamous cell carcinomas by modified en face frozen section margin-controlled technique.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Eyelid Neoplasms / surgery. Facial Neoplasms / surgery. Frozen Sections / methods. Skin Neoplasms / surgery. Surgical Procedures, Operative / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Incidence. Intraoperative Period. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / pathology. Retrospective Studies. Time Factors. Treatment Outcome. United States / epidemiology. Young Adult

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  • (PMID = 20348860.001).
  • [ISSN] 1536-9617
  • [Journal-full-title] International ophthalmology clinics
  • [ISO-abbreviation] Int Ophthalmol Clin
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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