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12. Pajor A, Stańczyk R, Durko T: [Malignant neoplasms of external and middle ear]. Otolaryngol Pol; 2005;59(2):251-6
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  • [Title] [Malignant neoplasms of external and middle ear].
  • INTRODUCTION: Neoplasms of external and middle ear are rare, which cause several problems in diagnosis and therapy.
  • The purpose of the study was to analyze retrospectively patients with malignant neoplasms of the ear.
  • METHODOLOGY: The study was carried out on 53 patients treated for malignant ear neoplasms in single institution during 25 years (1978-2002).
  • RESULTS: The most frequent neoplasm was squamous cell carcinoma--36 cases (67.9%), then basal cell carcinoma--9 cases (16.9%).
  • Neoplasm primarily involved auricle in 26 patients (49.1%), external auditory canal in 15 patients (28.3%) and middle ear in 12 patients (22.6%).
  • RESULTS: Neoplasms of external and middle ear constitute a group of various histopathological and clinical tumours, which differ in diagnostic difficulties, treatment and prognosis.
  • A diagnosis was often made in advanced stages of neoplasms, especially for middle ear tumours, that diminished a possibility of effective treatment.
  • [MeSH-major] Ear Neoplasms / pathology. Ear, External. Ear, Middle
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / therapy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / therapy. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasm Staging. Ossicular Prosthesis. Retrospective Studies

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  • (PMID = 16095097.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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13. Bridges MN, Doval M: Cutaneous squamous cell carcinoma of the external auditory canal. Dermatol Online J; 2009;15(2):13
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  • [Title] Cutaneous squamous cell carcinoma of the external auditory canal.
  • Cutaneous squamous cell carcinoma (SCC) along with basal cell carcinoma (BCC), collectively known as Nonmelanoma skin cancer (NMSC), are the most common cancers in the United States.
  • Squamous cell carcinoma of the skin is less common than BCC, but is known to be more aggressive with a higher mortality rate.
  • Squamous cell carcinoma of the external auditory canal (EAC) is rare when compared to SCC on other cutaneous sites.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Ear Canal. Neoplasm Invasiveness / pathology. Otologic Surgical Procedures / methods. Skin Neoplasms / pathology


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4. Moloney FJ, Comber H, O'Lorcain P, O'Kelly P, Conlon PJ, Murphy GM: A population-based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol; 2006 Mar;154(3):498-504
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  • The standardized incidence rates for invasive NMSC (33-fold increase) and in situ carcinoma of the skin (65-fold increase) were significantly increased (P < 0.05).
  • The risk for invasive squamous cell carcinoma (SCC) was increased 82-fold compared with the nontransplanted population.
  • Male RTRs were at particular risk of invasive SCC at sun-exposed sites such as the scalp and the external ear.
  • The high incidence of SCC, basal cell carcinoma and Bowen's disease in the early post-transplant period for older patients and the cumulative risk in younger patients with increased duration of transplantation highlight the importance of implementing early and continued cancer surveillance regimens post-transplant.
  • [MeSH-minor] Adult. Age Factors. Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / immunology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / immunology. Epidemiologic Methods. Female. Humans. Immunocompromised Host. Immunosuppression / adverse effects. Ireland / epidemiology. Male. Sex Distribution


15. Cabanillas M, Pérez-Pérez L, Sánchez-Aguilar D, Fernández-Redondo V, Toribio J: [Acrokeratosis paraneoplastica with bullous lesions associated with esophageal squamous cell carcinoma]. Actas Dermosifiliogr; 2006 Apr;97(3):196-9
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  • [Title] [Acrokeratosis paraneoplastica with bullous lesions associated with esophageal squamous cell carcinoma].
  • [Transliterated title] Acroqueratosis paraneoplásica con lesiones ampollosas asociada a carcinoma epidermoide esofágico.
  • The digestive endoscopy revealed a squamous cell carcinoma in the proximal esophagus.
  • The histopathological study of the bullous lesions showed the presence of a subepidermal bulla, and direct immunofluorescence revealed granular deposits of IgG, IgA and C3 in the basal membrane of the healthy perilesional skin.
  • [MeSH-major] Acrodermatitis / etiology. Blister / etiology. Carcinoma, Squamous Cell / complications. Esophageal Neoplasms / complications. Keratosis / etiology. Paraneoplastic Syndromes / etiology
  • [MeSH-minor] Deglutition Disorders / etiology. Ear, External. Fatal Outcome. Hepatic Encephalopathy / etiology. Humans. Liver Neoplasms / complications. Liver Neoplasms / secondary. Male. Middle Aged. Pleural Effusion, Malignant / etiology. Wasting Syndrome / etiology


16. Morselli P, Zollino I, Pinto V, Brunelli G, Carinci F: Evaluation of clinical prognostic factors in T1 N0 M0 head and neck basal cell carcinoma. J Craniofac Surg; 2009 Jan;20(1):98-100
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  • [Title] Evaluation of clinical prognostic factors in T1 N0 M0 head and neck basal cell carcinoma.
  • This retrospective study was carried out to assess the clinical outcome of stage I (ie, T1 N0 M0) head and neck basal cell carcinoma (HNBCC) and verify the impact of some clinical parameters on prognosis.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Head and Neck Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cheek / surgery. Disease-Free Survival. Ear Neoplasms / surgery. Ear, External / surgery. Eyelid Neoplasms / surgery. Facial Neoplasms / surgery. Female. Follow-Up Studies. Humans. Lip Neoplasms / surgery. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Nose Neoplasms / surgery. Prognosis. Reoperation. Retrospective Studies. Treatment Outcome

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  • (PMID = 19165001.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Leibovitch I, Huilgol SC, Richards S, Paver R, Selva D: The Australian Mohs database: short-term recipient-site complications in full-thickness skin grafts. Dermatol Surg; 2006 Nov;32(11):1364-8
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  • Most tumors were basal call carcinoma (90.9%) and were located on the nose (63.8%), periocular area (14.8%), or auricular area (8.1%).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Australia / epidemiology. Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / etiology. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Databases, Factual. Ear, External. Female. Forehead. Graft Survival. Humans. Male. Middle Aged. Mohs Surgery / statistics & numerical data. Nose. Postoperative Complications. Prospective Studies. Treatment Outcome

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  • (PMID = 17083589.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Schmerber S, Righini Ch, Soriano E, Delalande C, Dumas G, Reyt E, Lavieille JP: [The outcome of treatments for carcinoma of the external auditory canal]. Rev Laryngol Otol Rhinol (Bord); 2005;126(3):165-70
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  • [Title] [The outcome of treatments for carcinoma of the external auditory canal].
  • OBJECTIVE: A retrospective analysis of management and survival of patients treated for temporal bone carcinoma.
  • PATIENTS AND METHODS: Thirty patients underwent treatment for carcinoma of the temporal bone.
  • Twenty-five squamous cell carcinomas, 1 melanoma, 2 basocellular carcinomas and 2 adenoid cystic carcinomas were treated.
  • CONCLUSION: Long-term prognosis of the carcinoma of the external auditory canal mainly depends on the stage and primary treatment.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Carcinoma, Basal Cell / therapy. Carcinoma, Squamous Cell / therapy. Ear Canal. Ear Neoplasms / therapy. Ear, Middle. Melanoma / therapy. Skull Neoplasms / therapy. Temporal Bone

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  • (PMID = 16366384.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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19. Geng A, Weinstock MA, Hall R, Eilers D, Naylor M, Kalivas J, VATTC Trial Group: Tolerability of high-dose topical tretinoin: the Veterans Affairs Topical Tretinoin Chemoprevention Trial. Br J Dermatol; 2009 Oct;161(4):918-24
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  • METHODS: A randomized, multicentre, double-blind, controlled trial for chemoprevention of keratinocyte carcinomas (i.e. basal cell or squamous cell carcinomas) using topical tretinoin cream to the face and ears was conducted.

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  • (PMID = 19681859.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA106592; United States / NCI NIH HHS / CA / R25CA087972; United States / NCI NIH HHS / CA / R01CA106807; United States / NCI NIH HHS / CA / R01CA106592; United States / NIAMS NIH HHS / AR / R01AR49342
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 5688UTC01R / Tretinoin
  • [Investigator] Weinstock M; Marcolivio K; Weinstock M; Bingham S; DiGiovanna JJ; Hall R; Naylor M; Taylor JR; Vertrees J; White C; Hall R; Sidhu-Malik N; Hannah D; Eilers D; Liang T; Sakla N; Kreuger A; Cole G; Jeffes E; Labrador T; Taylor JR; Kirsner R; Kerri JE; Falabella AG; Givens M; Naylor M; Benson MB; Perry L; Kalivas J; Yanni C; Targovnik S; Austin J; Collier S; Collins JF; Bingham S; Calvert B; Connor P; Crigler C; Davis D; Grubb P; Kelly J; Kirk G; Lawson K; Linzy L; Palmer L; Rhoads M; Sather M; Copeland E; Fye C; Gagne W; de Naranjo PG; Messick C; Vertrees J; Piepkorn M; White C; Lew R; Braverman I; Cole B; Kalish R; McLean D; Thiers BH
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20. Puxeddu R, Dennis S, Ferreli C, Caldera S, Brennan PA: Platysma myocutaneous flap for reconstruction of skin defects in the head and neck. Br J Oral Maxillofac Surg; 2008 Jul;46(5):383-6
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  • We present our results of using a superiorly based PMF flap for reconstruction of defects in the parotid, auricular/mastoid, and cheek regions after resection for squamous cell carcinoma.
  • [MeSH-minor] Adenocarcinoma / surgery. Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Cheek / surgery. Ear, External / surgery. Female. Humans. Hyperemia / etiology. Male. Middle Aged. Muscle, Skeletal / blood supply. Muscle, Skeletal / transplantation. Parotid Neoplasms / surgery. Parotid Region / surgery. Retrospective Studies. Skin Transplantation


21. D'Arpa S, Cordova A, Moschella F: Further application of the bilobed flap: the split bilobed flap for reconstruction of composite posterior auricular and mastoid defects. J Plast Reconstr Aesthet Surg; 2006;59(12):1330-5
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  • Direct closure with undermining, if feasible, will obliterate the retroauricular sulcus causing asymmetry with the contralateral ear and, if defects are cephalad will impair the possibility of wearing spectacles, thus leaving functional and aesthetic impairment.
  • Two patients, both affected by basal cell carcinoma involving the posteromedial auricular surface and the mastoid skin have been treated with this flap.
  • [MeSH-major] Ear Deformities, Acquired / surgery. Ear, External / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / surgery. Ear Neoplasms / surgery. Head and Neck Neoplasms / surgery. Humans. Male. Mastoid

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  • (PMID = 17113512.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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22. Garvey C, Garvey K, Hendi A: A review of common dermatologic disorders of the external ear. J Am Acad Audiol; 2008 Mar;19(3):226-32
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  • [Title] A review of common dermatologic disorders of the external ear.
  • Skin disorders of the external ear are common.
  • The cutaneous disorders of the external ear discussed in the article are divided into benign, premalignant, and malignant groups.
  • [MeSH-major] Dermatitis, Seborrheic / pathology. Ear, External / pathology
  • [MeSH-minor] Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Humans. Malassezia / isolation & purification. Melanoma / pathology. Photosensitivity Disorders / microbiology. Photosensitivity Disorders / pathology. Pruritus / diagnosis. Pruritus / etiology. Psoriasis / pathology. Skin Neoplasms / pathology

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  • (PMID = 18672650.001).
  • [ISSN] 1050-0545
  • [Journal-full-title] Journal of the American Academy of Audiology
  • [ISO-abbreviation] J Am Acad Audiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 10
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23. Caputo CL: Dramatic signs with cranial nerve deficit. JAAPA; 2006 Nov;19(11):57
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Cranial Nerve Diseases / etiology. Ear, External. Neoplasm Recurrence, Local / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17124793.001).
  • [ISSN] 1547-1896
  • [Journal-full-title] JAAPA : official journal of the American Academy of Physician Assistants
  • [ISO-abbreviation] JAAPA
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Osborne RF, Shaw T, Zandifar H, Kraus D: Elective parotidectomy in the management of advanced auricular malignancies. Laryngoscope; 2008 Dec;118(12):2139-45
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  • Patients with a clinical history of advanced nonmelanoma auricular carcinoma undergoing elective parotidectomy and/or neck dissection with clinically and radiographically N0 nodal disease were evaluated for the presence of occult parotid metastasis.
  • All patients underwent parotidectomy in conjunction with a total auriculectomy for surgical extirpation of their primary auricular carcinoma.
  • CONCLUSIONS: Parotidectomy may not be necessary in the surgical management of advanced auricularcarcinoma in the absence of clinically positive parotid disease or external auditory canal involvement.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Ear Neoplasms / surgery. Ear, External. Elective Surgical Procedures. Parotid Gland / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Ear Canal / pathology. Female. Humans. Male. Middle Aged. Neck Dissection. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Parotid Neoplasms / pathology. Parotid Neoplasms / secondary. Parotid Neoplasms / surgery. Retrospective Studies. Risk Factors

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  • (PMID = 19029866.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Nazarian Y, Shalmon B, Horowitz Z, Bedrin L, Pfeffer MR, Talmi YP: Merkel cell carcinoma of unknown primary site. J Laryngol Otol; 2007 Apr;121(4):e1
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  • [Title] Merkel cell carcinoma of unknown primary site.
  • Merkel cell carcinoma is an uncommon and aggressive primary neuroendocrine skin malignancy which mostly affects the extremities and the head and neck region of elderly patients.
  • Merkel cell carcinoma occurs with increased frequency in sun-exposed areas, in individuals exposed to arsenic and in immunosuppressed patients.
  • Many patients with Merkel cell carcinoma present with other malignancies, mainly skin cancers.
  • Merkel cell carcinoma of unknown primary site is rare, and the majority of the few cases described have not been from head and neck areas.
  • We present a case of Merkel cell carcinoma of unknown primary site, with upper neck and distant metastases.
  • [MeSH-major] Carcinoma, Merkel Cell / secondary. Ear Neoplasms / secondary. Head and Neck Neoplasms / secondary. Neoplasms, Unknown Primary / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / secondary. Ear, External. Facial Neoplasms / pathology. Humans. Male

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  • (PMID = 17319999.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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26. Cordova A, Di Lorenzo S, Moschella F: "Composite graft": a simple option for nasal lining. Int J Dermatol; 2007 Apr;46(4):417-21
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  • CONCLUSIONS: The use of a composite graft for internal lining and a forehead flap for external skin allowed is to obtain good results with minimal retraction.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Ear Cartilage / transplantation. Nose / surgery. Rhinoplasty / methods. Skin Neoplasms / surgery. Surgical Flaps

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  • (PMID = 17442089.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Dib LL, de Oliveira JA, Neves RI, Sandoval RL, Nannmark U: Auricular rehabilitation by means of bone grafting from the iliac crest in combination with porous extraoral implants: a case report. Clin Implant Dent Relat Res; 2007 Dec;9(4):228-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Basal Cell / rehabilitation. Ear, External / surgery. Head and Neck Neoplasms / rehabilitation. Prostheses and Implants. Prosthesis Implantation

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  • (PMID = 18031445.001).
  • [ISSN] 1523-0899
  • [Journal-full-title] Clinical implant dentistry and related research
  • [ISO-abbreviation] Clin Implant Dent Relat Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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28. Turan A, Turkaslan T, Kul Z, Isler C, Ozsoy Z: Reconstruction of the anterior surface of the ear using a postauricular pull-through neurovascular island flap. Ann Plast Surg; 2006 Jun;56(6):609-13
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  • [Title] Reconstruction of the anterior surface of the ear using a postauricular pull-through neurovascular island flap.
  • The auricular conchal cavity is a shallow structure in the central part of the ear.
  • It is not only 3-dimensional, but it is a gateway to the external ear canal.
  • We used postauricular neurovascular pedicle island flap for conchal and periconchal areas of anterior surface of the external ear because it matches to the skin color, thickness and texture; scars are well hidden, and there is no donor-site morbidity.
  • The static 2-point discriminations in the transferred flap and in the other ear, which corresponds to the same area, were measured.
  • We advocate postauricular neurovascular pedicle island flap for conchal and periconchal areas of anterior surface of the external ear because it matches the skin color, thickness and texture; scars are well hidden, and there is no donor site morbidity.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Ear Neoplasms / surgery. Ear, External / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps

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  • (PMID = 16721071.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Rio E, Bardet E, Ferron C, Peuvrel P, Supiot S, Campion L, Beauvillain De Montreuil C, Mahe MA, Dreno B: [Interstitial brachytherapy of peri-orificial skin carcinomas on the face]. Cancer Radiother; 2006 May;10(3):101-6
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  • - We performed a retrospective analysis of 97 skin carcinomas (88 basal cell carcinomas (BCCs), 9 squamous cell carcinomas (SCCs)) of the nose, periorbital areas and ears from 40 previously untreated patients (group 1) and 57 patients who had undergone surgery (group 2).
  • [MeSH-major] Brachytherapy. Carcinoma, Basal Cell / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Ear Neoplasms / radiotherapy. Ear, External. Eyelid Neoplasms / radiotherapy. Nose Neoplasms / radiotherapy. Skin Neoplasms / radiotherapy

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  • (PMID = 16529964.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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30. Bojanović M, Zivković-Marinkov E, Veselinović D, Bojanović A, Vucković I: [Malignant tumors of auricula and periauricular area]. Vojnosanit Pregl; 2009 Aug;66(8):611-6
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  • CONCLUSION: Carcinoma of auricular and periauricular area should be confirmed by biopsy and histopathologic evaluation.
  • [MeSH-major] Ear Neoplasms. Ear, External. Skin Neoplasms
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Middle Aged

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  • (PMID = 19780414.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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31. Landström FJ, Nilsson CO, Crafoord S, Reizenstein JA, Adamsson GB, Löfgren LA: Electroporation therapy of skin cancer in the head and neck area. Dermatol Surg; 2010 Aug;36(8):1245-50
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  • BACKGROUND: Electroporation therapy is a new cancer treatment modality in which a locally applied electrical field enhances cell membrane permeability, allowing greater intracellular accumulation of a chemotherapeutic agent.
  • OBJECTIVE: To evaluate the efficacy of electroporation therapy in treating basal cell and squamous cell carcinomas of the skin.
  • Orbital growth, facial nerve proximity, or proximity to cartilage of the external meatus complicated four of these tumors.
  • [MeSH-major] Antibiotics, Antineoplastic / administration & dosage. Bleomycin / administration & dosage. Carcinoma, Basal Cell / drug therapy. Carcinoma, Squamous Cell / drug therapy. Electrochemotherapy. Head and Neck Neoplasms / drug therapy. Skin Neoplasms / drug therapy
  • [MeSH-minor] Aged. Aged, 80 and over. Ear Neoplasms / drug therapy. Female. Humans. Male. Neoplasm Recurrence, Local / drug therapy

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  • [CommentIn] Dermatol Surg. 2011 Feb;37(2):286; author reply 287 [21324036.001]
  • (PMID = 20666812.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin
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32. Cordova A, Pirrello R, D'Arpa S, Moschella F: Superior pedicle retroauricular island flap for ear and temporal region reconstruction: anatomic investigation and 52 cases series. Ann Plast Surg; 2008 Jun;60(6):652-7
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  • [Title] Superior pedicle retroauricular island flap for ear and temporal region reconstruction: anatomic investigation and 52 cases series.
  • BACKGROUND: On the basis of a previously published anatomic study on the superior auricular artery (SAA) and on a series of 52 consecutive cases, the authors propose a new superior pedicle retroauricular island flap (SP-RIF) for defects of the upper half of the ear and for temporal region or superficial helical defects.
  • In 51 cases, the defect involved the upper half of the ear.
  • CONCLUSIONS: The SP-RIF can be considered as a first choice option to repair nonmarginal losses of substance of the upper half of the ear.
  • [MeSH-major] Ear, External / surgery. Face / anatomy & histology. Face / surgery. Reconstructive Surgical Procedures / methods. Skin Transplantation / methods. Surgical Flaps
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cadaver. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Ear Neoplasms / surgery. Esthetics. Humans. Middle Aged

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  • (PMID = 18520202.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Mathews SS, Ninan S: Reconstruction of the conchal bowl and external auditory canal. Ear Nose Throat J; 2006 Jul;85(7):425
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  • [Title] Reconstruction of the conchal bowl and external auditory canal.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Ear Canal / surgery. Ear Cartilage / surgery. Ear Neoplasms / surgery. Reconstructive Surgical Procedures / methods

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  • (PMID = 16909809.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Rio E, Bardet E, Ferron C, Peuvrel P, Supiot S, Campion L, De Montreuil CB, Mahe MA, Dreno B: Interstitial brachytherapy of periorificial skin carcinomas of the face: a retrospective study of 97 cases. Int J Radiat Oncol Biol Phys; 2005 Nov 1;63(3):753-7
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  • PATIENTS AND METHODS: We performed a retrospective analysis of 97 skin carcinomas (88 basal cell carcinomas, 9 squamous cell carcinomas) of the nose, periorbital areas, and ears from 40 previously untreated patients (Group 1) and 57 patients who had undergone surgery (Group 2).
  • [MeSH-major] Brachytherapy / methods. Carcinoma, Basal Cell / radiotherapy. Carcinoma, Squamous Cell / radiotherapy. Facial Neoplasms / radiotherapy. Skin Neoplasms / radiotherapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bias (Epidemiology). Ear Neoplasms / radiotherapy. Ear, External. Esthetics. Eyelid Neoplasms / radiotherapy. Female. Humans. Iridium Radioisotopes / therapeutic use. Male. Middle Aged. Neoplasm Recurrence, Local. Nose Neoplasms / radiotherapy. Radiotherapy Dosage. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 15927410.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iridium Radioisotopes
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35. El Demellawy D, Escott N, Salama S, Alowami S: Sebaceoma of the external ear canal: an unusual location. Case report and review of the literature. J Cutan Pathol; 2008 Oct;35(10):963-6
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  • [Title] Sebaceoma of the external ear canal: an unusual location. Case report and review of the literature.
  • Sebaceous neoplasms of the external ear canal are extremely rare.
  • Only two cases of sebaceous neoplasms have been reported in the English literature, a sebaceous carcinoma and a sebaceous adenoma.
  • We report a case of sebaceoma of the external ear canal.
  • We highlight the differential diagnosis, particularly sebaceous carcinoma and basal cell carcinoma with sebaceous differentiation.
  • [MeSH-major] Ear Canal / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Sebaceous / pathology. Aged. Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry

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  • (PMID = 18564279.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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36. Madsen AR, Gundgaard MG, Hoff CM, Maare C, Holmboe P, Knap M, Thomsen LL, Buchwald C, Hansen HS, Bretlau P, Grau C: Cancer of the external auditory canal and middle ear in Denmark from 1992 to 2001. Head Neck; 2008 Oct;30(10):1332-8
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  • [Title] Cancer of the external auditory canal and middle ear in Denmark from 1992 to 2001.
  • METHODS: Review of 68 consecutive cases: 47 squamous cell carcinoma, 10 basal cell carcinoma, and 11 other histologies.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / therapy. Ear Canal. Ear Neoplasms / pathology. Ear Neoplasms / therapy. Ear, Middle

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  • [Copyright] Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
  • (PMID = 18704969.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Descamps MJ, Hiscutt EL, Critchley P: A nodule on the ear with unique histological features. Clin Exp Dermatol; 2008 Jul;33(4):531-2
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  • [Title] A nodule on the ear with unique histological features.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Ear, External / pathology. Keloid / pathology. Skin Neoplasms / pathology

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  • (PMID = 18582239.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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38. Volkenstein S, Dazert S, Jahnke K, Schneider M, Neumann A: [Prosthetic supply of tissue defects in head and neck surgery]. Laryngorhinootologie; 2007 Dec;86(12):854-60
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  • [MeSH-major] Ear Neoplasms / surgery. Ear, External / surgery. Facial Injuries / surgery. Nose Neoplasms / surgery. Orbital Neoplasms / surgery. Prosthesis Design. Prosthesis Implantation / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Combined Modality Therapy. Female. Hemangioendothelioma / surgery. Humans. Male. Melanoma / surgery. Middle Aged. Orbit Evisceration. Paranasal Sinus Neoplasms / surgery. Radiation Injuries / surgery. Reoperation

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  • (PMID = 18183648.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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39. Karsidag S, Ozcan A, Ozkaya O, Ugurlu K, Bas L: Use of wide bipedicled pericranial flap in anterior scalp reconstruction. J Craniofac Surg; 2009 Nov;20(6):2248-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Ear, External / blood supply. Fascia / transplantation. Humans. Male. Middle Aged. Periosteum / transplantation. Skin Transplantation


40. Richmond-Sinclair NM, Pandeya N, Ware RS, Neale RE, Williams GM, van der Pols JC, Green AC: Incidence of basal cell carcinoma multiplicity and detailed anatomic distribution: longitudinal study of an Australian population. J Invest Dermatol; 2009 Feb;129(2):323-8
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  • [Title] Incidence of basal cell carcinoma multiplicity and detailed anatomic distribution: longitudinal study of an Australian population.
  • A proportion of individuals are affected multiple times by basal cell carcinoma (BCC), but the rate and extent to which this occurs is unknown.
  • [MeSH-major] Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / pathology. Face / pathology. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Cheek / pathology. Ear, External / pathology. Female. Forehead / pathology. Humans. Incidence. Longitudinal Studies. Male. Middle Aged. Nose / pathology. Queensland / epidemiology. Sunlight / adverse effects

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  • (PMID = 18668137.001).
  • [ISSN] 1523-1747
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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41. Gunay Y, Erkan M, Gurbuzer B, Karayazgan B: Facilitation of facial prosthesis placement with tattoo markers: a clinical report. J Prosthet Dent; 2007 May;97(5):256-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Ear, External. Prostheses and Implants. Prosthesis Design / methods. Skin Neoplasms / surgery. Tattooing

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  • (PMID = 17547942.001).
  • [ISSN] 0022-3913
  • [Journal-full-title] The Journal of prosthetic dentistry
  • [ISO-abbreviation] J Prosthet Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Crain N, Nelson BL, Barnes EL, Thompson LD: Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases. Head Neck Pathol; 2009 Mar;3(1):1-17
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  • BACKGROUND: Ceruminal gland carcinomas are rare neoplasms confined to the skin lining the cartilaginous part of the external auditory canal.
  • Patients presented clinically with a mass of the outer half of the external auditory canal (n = 14), hearing changes (n = 5), drainage (n = 4), or paralysis of the facial nerve (n = 3).
  • Histologic features included a dual cell population (although not the dominant histology), increased cellularity, moderate to severe nuclear pleomorphism, irregular nucleoli, increased mitotic figures (mean, 3/10 HPF), including atypical forms, and tumor necrosis (n = 2).
  • Tumors were divided into three types of adenocarcinoma based on pattern of growth and cell type (ceruminous, NOS [n = 12], adenoid cystic [n = 4], mucoepidermoid [n = 1]).
  • CK7 and CD117 highlighted the luminal cells, while S1-00 protein showed a predilection for the basal cells of ceruminous and adenoid cystic carcinomas.
  • CONCLUSION: Ceruminous-type carcinomas, with the exception of ceruminous mucoepidermoid carcinoma, all demonstrated a dual cell population of basal myoepithelial-type cells and luminal apocrine cells.
  • [MeSH-major] Carcinoma / pathology. Ear Neoplasms / pathology. Ear, External / pathology

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  • (PMID = 20596983.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807538
  • [Keywords] NOTNLM ; Adenoid cystic / Carcinoma / Ceruminal / Ceruminous / Ear / Gland / Immunohistochemistry / Mucoepidermoid / Prognosis
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43. Wiatr M, Składzieiń J: [Own experiences in treatment of the external and middle ear tumors from data collected between 1992-2001]. Przegl Lek; 2007;64(7-8):462-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Own experiences in treatment of the external and middle ear tumors from data collected between 1992-2001].
  • We discuss a retrospective study of patients with malignant tumors of the external and middle ear operated at the Otolaryngology Department of the Jagiellonian University in Cracow between 1992-2001.
  • In our population the most common tumor was basal cell carcinoma located on the auricle in T1 stage.
  • The most common lesion located in the middle ear or middle and external ear was the squamous cell carcinoma in T2 stage.
  • [MeSH-major] Carcinoma, Basal Cell. Carcinoma, Squamous Cell. Ear Neoplasms / pathology. Ear Neoplasms / surgery
  • [MeSH-minor] Aged. Combined Modality Therapy. Ear, External / surgery. Ear, Middle / surgery. Female. Humans. Male. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 18409345.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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