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4. Wei CC, Sanfilippo NJ, Myssiorek D: Re-irradiation of metastatic disease in the neck from xeroderma pigmentosum. Curr Oncol; 2010 Jun;17(3):83-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mutation of these enzymes leads to the development of multiple basal cell and squamous cell carcinomas.
  • OBJECTIVES: We present a case of xeroderma pigmentosum in a patient with cervical and intraparotid metastatic disease from recurrent cutaneous squamous cell carcinomas of the face and scalp, treated with neck dissection and re-irradiation.
  • With the illustrative case report, we include a literature review of diagnosis, prognostic factors, and treatment, with emphasis on surgical and radiation treatment of cervical metastatic disease from recurrent skin carcinomas.
  • CASE PRESENTATION: A xeroderma pigmentosum patient presented to our clinic with a 2-cm right submental and 1-cm right infra-auricular mass after resection of multiple squamous cell carcinomas of the scalp and face, and external-beam radiation therapy to the right face and neck.
  • Fine-needle aspiration biopsy of the submental mass revealed poorly differentiated squamous cell carcinoma.
  • Surgical pathology revealed 3 level ia and supraclavicular lymph nodes that were positive for metastatic squamous cell carcinoma.
  • CONCLUSIONS: To our knowledge, this is the first case report in the literature of a patient with xeroderma pigmentosum who subsequently developed metastatic disease from recurrent cutaneous squamous cell carcinoma.

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  • [Cites] J Cutan Med Surg. 1998 Jan;2(3):153-8 [9479081.001]
  • [Cites] Radiother Oncol. 2000 Nov;57(2):143-54 [11054518.001]
  • [Cites] Anticancer Drugs. 2006 Feb;17(2):133-8 [16428930.001]
  • [Cites] Adv Exp Med Biol. 2008;637:19-27 [19181107.001]
  • [Cites] Radiother Oncol. 2006 Oct;81(1):1-8 [16971009.001]
  • [Cites] Eur J Dermatol. 2009 Mar-Apr;19(2):163-5 [19106040.001]
  • [Cites] Br J Radiol. 2006 Jun;79(942):510-7 [16714754.001]
  • (PMID = 20567629.001).
  • [ISSN] 1718-7729
  • [Journal-full-title] Current oncology (Toronto, Ont.)
  • [ISO-abbreviation] Curr Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2880910
  • [Keywords] NOTNLM ; Xeroderma pigmentosum / head-and-neck cancer / radiation / re-irradiation
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5. Pragnell J, Neilson J: The social and psychological impact of hard-to-heal wounds. Br J Nurs; 2010 Oct 28-Nov 10;19(19):1248-52
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  • This article examines the experience of a woman treated for basal cell carcinoma of the scalp--both the immediate emotional impact of the individual stages of treatment and the wider impact on her lifestyle and her family.
  • [MeSH-major] Attitude to Health. Carcinoma, Basal Cell / psychology. Cost of Illness. Scalp. Skin Neoplasms / psychology. Wound Healing
  • [MeSH-minor] Amelogenin / economics. Amelogenin / therapeutic use. Exudates and Transudates. Female. Humans. Life Style. Middle Aged. Mohs Surgery. Pain / etiology. Quality of Life / psychology. Skin Care / methods. Skin Care / nursing. Skin Care / psychology. Surgical Flaps

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  • (PMID = 21155363.001).
  • [ISSN] 0966-0461
  • [Journal-full-title] British journal of nursing (Mark Allen Publishing)
  • [ISO-abbreviation] Br J Nurs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Amelogenin
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6. Hassanpour SE, Kalantar-Hormozi A, Motamed S, Moosavizadeh SM, Shahverdiani R: Basal cell carcinoma of scalp in patients with history of childhood therapeutic radiation: a retrospective study and comparison to nonirradiated patients. Ann Plast Surg; 2006 Nov;57(5):509-12
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  • [Title] Basal cell carcinoma of scalp in patients with history of childhood therapeutic radiation: a retrospective study and comparison to nonirradiated patients.
  • BACKGROUND: Basal cell carcinoma (BCC) is the most common human malignant neoplasm.
  • Some patients with scalp BCC have had a history of childhood scalp radiation for the treatment of tinea capitis.
  • MATERIALS AND METHODS: From 1995 to 2005, a total of 74 patients were diagnosed with scalp BCC.
  • Thirty-eight patients (group A) had a history of childhood radiation to the scalp for the treatment of tinea capitis, and the other 36 (group B) did not.
  • Patients in group A had a longer history of scalp lesions (P = 0.001).
  • CONCLUSION: BCC in irradiated scalp has a more aggressive behavior and may need a more aggressive surgical resection.
  • Also, these patients should be under close observation because there is a higher chance for tumor recurrence and also new lesions occurring elsewhere in the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / radiotherapy. Carcinoma, Basal Cell / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / radiotherapy. Skin Neoplasms / surgery. Survivors / statistics & numerical data
  • [MeSH-minor] Adult. Aged. Child. Female. Humans. Male. Middle Aged. Retrospective Studies. Scalp. Treatment Outcome

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  • [CommentIn] Ann Plast Surg. 2007 May;58(5):589; author reply 589-90 [17452854.001]
  • (PMID = 17060730.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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7. Satter EK, Derienzo DP: Synchronous onset of multiple cutaneous neuroendocrine (Merkel cell) carcinomas localized to the scalp. J Cutan Pathol; 2008 Jul;35(7):685-91
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  • [Title] Synchronous onset of multiple cutaneous neuroendocrine (Merkel cell) carcinomas localized to the scalp.
  • Merkel cell carcinoma (MCC) is a rare aggressive neoplasm that typically presents as a solitary nodule or plaque on sun-exposed skin of the elderly.
  • We report a case of a 59-year-old white male who presented with abrupt onset of multiple small bluish papules on his frontal scalp.
  • On low power, the tumor had the overall histological silhouette of a nodular basal cell carcinoma.
  • However, because of the lack of an epithelial connection and the cell's cytomorphological features, a MCC was considered and was subsequently confirmed using immunohistochemical stains.
  • [MeSH-major] Carcinoma, Merkel Cell / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Lymph Nodes / pathology. Lymphatic Metastasis. Male. Middle Aged. Scalp / pathology

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  • (PMID = 18331571.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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8. Yazici AC, Unal S, Ikizoglu G, Kokturk A, Baz K, Cinel L, Koca A: Superficial basal cell carcinoma of the scalp mimicking seborrhoeic dermatitis. Scand J Plast Reconstr Surg Hand Surg; 2006;40(1):54-6
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  • [Title] Superficial basal cell carcinoma of the scalp mimicking seborrhoeic dermatitis.
  • Superficial basal cell carcinomas (BCC) comprise 9% to 11% of BCC, and are commonly found on the trunk or limbs.
  • We report a case of a superficial BCC on the scalp that was misdiagnosed and treated as seborrhoeic dermatitis.
  • Any erythematous plaque-type lesion of long duration must have superficial BCC considered in the differential diagnosis.

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  • (PMID = 16428215.001).
  • [ISSN] 0284-4311
  • [Journal-full-title] Scandinavian journal of plastic and reconstructive surgery and hand surgery
  • [ISO-abbreviation] Scand J Plast Reconstr Surg Hand Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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9. Kandamany N, Monk B: Basal cell carcinoma presenting late in a shotgun scar. Am J Clin Dermatol; 2009;10(4):271-2
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  • [Title] Basal cell carcinoma presenting late in a shotgun scar.
  • The development of a basal cell carcinoma (BCC) as a late complication of a shotgun injury is a rare clinical entity.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Cicatrix / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Scalp / injuries. Scalp / pathology. Wounds, Gunshot / pathology

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  • (PMID = 19489662.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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10. Mathieu D, Fortin D: Intracranial invasion of a basal cell carcinoma of the scalp. Can J Neurol Sci; 2005 Nov;32(4):546-8
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  • [Title] Intracranial invasion of a basal cell carcinoma of the scalp.
  • OBJECTIVE AND IMPORTANCE: Basal cell carcinomas are common lesions that can have a locally invasive behavior.
  • The authors present a case of a scalp lesion with skull and dura-mater invasion that was unrecognized prior to surgical undertaking.
  • CLINICAL PRESENTATION: A 66-year-old female presented with an extensive ulcerating lesion on the frontal scalp, deemed to be a basal cell carcinoma.
  • INTERVENTION: Resection of the invaded frontal scalp, bone, dura-mater and proximal part of the superior sagittal sinus was performed.
  • This was followed by a reconstructive procedure consisting of a duraplasty, a cranioplasty, and a skin rotation flap and partial-thickness skin grafting.
  • CONCLUSION: Radiological evaluation of scalp basal cell carcinomas should be done prior to surgery to rule out any bony or intracranial invasion.
  • [MeSH-major] Bone Neoplasms / pathology. Carcinoma, Basal Cell. Scalp / pathology. Skin Neoplasms. Skull / pathology

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  • (PMID = 16408590.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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11. Findley AB, Pride H: Unusual cystic scalp lesions in Gorlin syndrome: a brief report. Pediatr Dermatol; 2010 Mar-Apr;27(2):204-7
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  • [Title] Unusual cystic scalp lesions in Gorlin syndrome: a brief report.
  • Nevoid basal cell carcinoma syndrome (Gorlin syndrome) is a rare, autosomal dominant syndrome that is known to have variable expressivity in multiple organ systems.
  • We describe the case of a young male child with nevoid basal cell carcinoma syndrome and scalp lesions, including a branchial cleft cyst with respiratory epithelium and a rudimentary meningocele.
  • These are both new, previously unreported findings, possibly associated with nevoid basal cell carcinoma syndrome.
  • [MeSH-major] Basal Cell Nevus Syndrome / diagnosis. Branchioma / diagnosis. Head and Neck Neoplasms / diagnosis. Scalp. Skin Neoplasms / diagnosis


14. Filippou DK, Filippou G, Trigka A, Condilis N, Kiparidou E, Skandalakis P, Rizos S: Malignant proliferating trichilemmal tumour of the scalp. Report of a case and a short review of the literature. Ann Ital Chir; 2006 Mar-Apr;77(2):179-81
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  • [Title] Malignant proliferating trichilemmal tumour of the scalp. Report of a case and a short review of the literature.
  • BACKGROUND: Malignant proliferating trichilemmal tumour is a rare skin tumour that originates from the root sheath of the hair and usually arises in the sun-exposed areas of elderly women.
  • It mimicks poorly differential squamous cell carcinoma ant its biological behaviour is unpredictable, because rarely can produce distant metastases.
  • CASE REPORT: The Authors report on a case of a 54-year-old female patients who proceeded with a cystic lesion in the scalp.
  • The appropriate treatment includes wide resection and dose postoperative follow-up of the patient to facilitate the early diagnosis of distant metastases.
  • [MeSH-major] Neoplasms, Basal Cell / surgery. Scalp. Skin Neoplasms / surgery

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  • (PMID = 17147095.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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15. Tschen EH, Wong DS, Pariser DM, Dunlap FE, Houlihan A, Ferdon MB, Phase IV ALA-PDT Actinic Keratosis Study Group: Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up. Br J Dermatol; 2006 Dec;155(6):1262-9
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  • [Title] Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
  • AKs are believed to progress to in situ squamous cell carcinoma (SCC) and potentially, to invasive SCC.
  • (iii) to characterize the histopathology of untreated clinically diagnosed AK lesions in the study population at baseline; and (iv) to evaluate ALA-PDT in darker skin types than previously studied.
  • METHODS: Patients enrolled in this study had six to 12 discrete AK lesions, either on the face or the scalp.
  • With respect to the lesions biopsied, 91% (127/139) were diagnosed histopathologically as AK, with the balance of lesions being SCC (nine of 139: 7%), basal cell carcinoma (one of 139: 0.7%) and other non-AK diagnoses (two of 139: 1%).
  • The clinical diagnosis of AK by investigators appeared to be accurate, with 91% (200/220) of the untreated clinically diagnosed AK lesions being histopathologically confirmed to be AK (AK, 142/220: 65%; advanced AK, 29/220: 13%; macular AK, 29/220: 13%).
  • Despite concentrated efforts to recruit patients with Fitzpatrick skin types IV-VI, the distribution was as follows: I, 11%; II, 36%; III, 41%; IV, 11%; V, 2%.
  • CONCLUSIONS: ALA-PDT was shown to be an effective and safe therapy for the treatment of AKs of the face and scalp in skin types I-V, with an acceptable rate of recurrence over 12 months of histologically confirmed AKs of 19%.
  • Phototoxicity reactions were all expected, nonserious and had essentially resolved after 1 month post-treatment independent of skin type.
  • [MeSH-major] Aminolevulinic Acid / therapeutic use. Facial Dermatoses / drug therapy. Keratosis / drug therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Scalp Dermatoses / drug therapy

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  • (PMID = 17107399.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase IV; Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 88755TAZ87 / Aminolevulinic Acid
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16. Hantash BM, Stewart DB, Cooper ZA, Rehmus WE, Koch RJ, Swetter SM: Facial resurfacing for nonmelanoma skin cancer prophylaxis. Arch Dermatol; 2006 Aug;142(8):976-82
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  • [Title] Facial resurfacing for nonmelanoma skin cancer prophylaxis.
  • OBJECTIVE: To determine the effect of facial skin resurfacing for treatment of actinic keratoses (AKs) and prophylaxis against new primary basal and squamous cell carcinomas in individuals with previous nonmelanoma skin cancer (NMSC) or severe photodamage.
  • PATIENTS: Thirty-four patients with a history of facial or scalp AKs or basal or squamous cell carcinoma were enrolled.
  • Times from baseline to diagnosis of first skin cancer were compared between the treatment and control groups.
  • RESULTS: Treatment with fluorouracil, trichloroacetic acid, or carbon dioxide laser resulted in an 83% to 92% reduction in AKs (P< or =.03), a lower incidence of NMSC compared with the control group (P<.001), and a trend toward longer time to development of new skin cancer compared with the control group (P=.07).
  • CONCLUSION: All 3 modalities demonstrated benefit for AK reduction and skin cancer prophylaxis compared with controls and warrant further study in a larger trial.
  • [MeSH-major] Keratolytic Agents / administration & dosage. Keratosis / prevention & control. Low-Level Light Therapy. Skin Neoplasms / prevention & control
  • [MeSH-minor] Aged. Aged, 80 and over. Carbon Dioxide. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / prevention & control. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / prevention & control. Disease-Free Survival. Drug Administration Schedule. Face. Female. Fluorouracil / administration & dosage. Humans. Male. Middle Aged. Prospective Studies. Scalp. Severity of Illness Index. Treatment Outcome. Trichloroacetic Acid / administration & dosage


17. Farley R, Ratner D: Diagnosis and management of atypical fibroxanthoma. Skinmed; 2006 Mar-Apr;5(2):83-6
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  • [Title] Diagnosis and management of atypical fibroxanthoma.
  • A 90-year-old Caucasian man with a history of basal cell carcinoma and squamous cell carcinoma presented with a friable erythematous nodule on his scalp that had been present for several months.
  • What is your diagnosis?
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Scalp. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male

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  • (PMID = 16603840.001).
  • [ISSN] 1540-9740
  • [Journal-full-title] Skinmed
  • [ISO-abbreviation] Skinmed
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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18. Kovarik CL, Stewart D, Barnard JJ: Lethal basal cell carcinoma secondary to cerebral invasion. J Am Acad Dermatol; 2005 Jan;52(1):149-51
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  • [Title] Lethal basal cell carcinoma secondary to cerebral invasion.
  • Intracranial invasion by a basal cell carcinoma on the scalp is extremely rare.
  • We present an autopsy case of a 57-year-old woman who developed a large destructive basal cell carcinoma with extension through the calvarium and compression of the dura.
  • We compare 7 similar cases reported in the literature and review the risks for development of these aggressive fatal basal cell carcinomas on the scalp.
  • [MeSH-major] Brain Neoplasms / pathology. Carcinoma, Basal Cell / pathology. Scalp. Skin Neoplasms / pathology

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  • (PMID = 15627099.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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19. Fincher EF, Gladstone HB: Dual transposition flaps for the reconstruction of large scalp defects. J Am Acad Dermatol; 2009 Jun;60(6):985-9

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  • [Title] Dual transposition flaps for the reconstruction of large scalp defects.
  • BACKGROUND: Large scalp defects can be challenging to repair because of the inelasticity of the scalp.
  • We present a dual transposition flap to close a large defect following Mohs surgery for a basal cell carcinoma on the scalp.
  • METHODS: We describe and report the case of a man with a basal cell carcinoma on the scalp vertex who had been referred for Mohs micrographic surgery.
  • The surgery resulted in a large scalp defect.
  • CONCLUSIONS: This dual transposition flap is a good reconstructive option for large, immobile scalp defects.
  • [MeSH-major] Scalp / surgery. Surgical Flaps
  • [MeSH-minor] Adult. Carcinoma, Basal Cell / surgery. Head and Neck Neoplasms / surgery. Humans. Male. Mohs Surgery. Reconstructive Surgical Procedures / methods. Scalp Dermatoses / surgery. Skin Neoplasms / surgery

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  • (PMID = 19467369.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Patel P, Talpur R, Duvic M: Langerhans cell histiocytosis arising from a BCC: a case report and review of the literature. Cutis; 2010 Jun;85(6):295-300
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  • [Title] Langerhans cell histiocytosis arising from a BCC: a case report and review of the literature.
  • Langerhans cell histiocytosis (LCH) is a rare disease characterized by a proliferation of Langerhans cells.
  • Several organs may be involved, including the skin, bone, and central nervous system.
  • Langerhans cell histiocytosis has been found in combination with other skin lesions and systemic conditions, but no definitive conclusion exists for this phenomenon.
  • We present a case report of a 63-year-old woman who initially presented with 3 pink papules on her forehead that had developed sequentially within 1 month, all diagnosed by biopsy as basal cell carcinoma (BCC) and appropriately treated.
  • Concurrent with the appearance of the third BCC, the patient began developing crusted ulcerative nodules on her scalp.
  • Biopsy of 1 scalp nodule revealed a BCC, but a repeat biopsy of the same nodule weeks later revealed LCH.
  • Langerhans cell histiocytosis arising from a BCC is extremely rare.
  • [MeSH-major] Carcinoma, Basal Cell / complications. Histiocytosis, Langerhans-Cell / diagnosis. Skin Neoplasms / complications
  • [MeSH-minor] Aged. Female. Humans. Langerhans Cells / pathology. Male. Middle Aged. Scalp / pathology

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  • (PMID = 20666189.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Balle JR, Hasselager T: [Kaposi's sarcoma interpreted as haematoma]. Ugeskr Laeger; 2010 Aug 30;172(35):2388-9
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  • Kaposi's sarcoma is a frequent skin cancer in HIV-positive patients, but is relatively uncommon in HIV-negative and non-immune compromised patients.
  • We present a case of Kaposi's sarcoma of the face and scalp in a HIV-negative male with previous facial basal cell carcinoma.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Sarcoma, Kaposi / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Facial Neoplasms / diagnosis. Facial Neoplasms / pathology. Humans. Male. Scalp / pathology

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  • (PMID = 20825744.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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22. Hauser J, Homann HH, Drücke D, Kuhnen C, Esenwein SA, Steinau HU: [Desmoplastic neurotropic melanoma. Diagnosis and therapeutic procedures for a rare clinical entity]. Chirurg; 2006 Oct;77(10):939-42
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  • [Title] [Desmoplastic neurotropic melanoma. Diagnosis and therapeutic procedures for a rare clinical entity].
  • In this paper, a 79-year-old patient with a basal cell carcinoma and desmoplastic melanoma on the scalp is described, and the therapeutic procedure is discussed.
  • [MeSH-major] Melanoma / surgery. Neoplasms, Multiple Primary / surgery. Scalp / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Diagnosis, Differential. Female. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Surgical Flaps

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  • (PMID = 16425057.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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23. Nasir S, Kayikcioglu A, Aydin MA, Tunçbilek G: Coverage of the cranium with latissimus dorsi in the recurrent basal cell carcinoma of Gorlin syndrome: for protection against clinical invasion. J Craniofac Surg; 2006 May;17(3):599-602
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  • [Title] Coverage of the cranium with latissimus dorsi in the recurrent basal cell carcinoma of Gorlin syndrome: for protection against clinical invasion.
  • Gorlin's syndrome is a genetic disorder of autosomal dominant inheritance with characterized primarily by five major findings: multiple basal cell carsinoma (BCC), jaw cysts, pits on the palms and soles, ectopic calcification of the falx cerebri and skeletal anomalies.
  • The authors present a 25-year-old man affected by recurrent basal cell carcinoma on the scalp.
  • The fascial component of the scalp forms an additional layer between the skin and the cranium.
  • This structure creates an extra distance before the invasion into the cranium which needs to be penetrated by the skin tumor.
  • Muscle tissue transformed in scalp reconstruction imitates the fascia layer in forming an additional layer against the invasion of skin tumors such as recurrent BCC into the cranium.
  • Free flap reconstruction for recurrent scalp BCC can be best therapy model at Gorlin's syndrome.
  • [MeSH-major] Basal Cell Nevus Syndrome / surgery. Carcinoma, Basal Cell / surgery. Muscle, Skeletal / transplantation. Scalp / surgery. Skin Neoplasms / surgery. Skull / surgery
  • [MeSH-minor] Adult. Clinical Protocols. Fascia / transplantation. Follow-Up Studies. Humans. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / surgery. Skin Transplantation / methods

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  • (PMID = 16770207.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Buggiani G, Troiano M, Rossi R, Lotti T: Photodynamic therapy: off-label and alternative use in dermatological practice. Photodiagnosis Photodyn Ther; 2008 Jun;5(2):134-8
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  • Photodynamic therapy (PDT) is a treatment technique that permits the clearance of different skin lesions with high success rates in many dermatological diseases.
  • Worldwide recognized uses for PDT in dermatology include non-melanoma skin cancer, actinic keratoses, acne vulgaris, photorejuvenation, and hidradenitis suppurativa.
  • In the European Union, and in the USA, its indication is for the treatment of nonhyperkeratotic actinic keratoses (AKs) of the face and scalp, for basal cell carcinoma and for Bowen's disease.
  • [MeSH-major] Dermatology. Photochemotherapy. Skin Diseases / therapy

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  • (PMID = 19356644.001).
  • [ISSN] 1873-1597
  • [Journal-full-title] Photodiagnosis and photodynamic therapy
  • [ISO-abbreviation] Photodiagnosis Photodyn Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 44
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25. Kokcam I, Saki CE: A case of cutaneous myiasis caused by Wohlfahrtia magnifica. J Dermatol; 2005 Jun;32(6):459-63
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  • A 46-year-old male farmer with nevoid basal cell carcinoma syndrome (NBCCS) presented with the complaint of a blood-tinged discharge and pain in the left frontal-temporal region for three days.
  • Physical examination revealed live maggots in the ulcerous wound resulting from basal cell carcinoma.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Diptera / parasitology. Myiasis / diagnosis. Skin Diseases, Parasitic / diagnosis. Skin Neoplasms / pathology
  • [MeSH-minor] Agriculture. Animals. Face. Follow-Up Studies. Humans. Larva. Male. Middle Aged. Risk Assessment. Scalp. Treatment Outcome. Turkey

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  • (PMID = 16043920.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 22
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26. Baykal C, Buyukbabani N, Yazganoglu KD, Saglik E: [Tumors associated with nevus sebaceous]. J Dtsch Dermatol Ges; 2006 Jan;4(1):28-31
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  • BACKGROUND: Nevus sebaceus (NS) is a congenital hamartomatous lesion, usually involving the scalp or the face.
  • Various benign and malignant neoplasms can develop in association with NS, the most common being trichoblastoma, syringocystadenoma papilliferum, viral warts and basal cell carcinoma (BCC).
  • CONCLUSION: Clinical features are not sufficient enough to make an exact diagnosis of benign or malignant secondary tumors.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Second Primary / diagnosis. Nevus / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Facial Neoplasms / diagnosis. Facial Neoplasms / pathology. Female. Humans. Male. Middle Aged. Scalp / pathology. Skin / pathology

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  • (PMID = 16503928.001).
  • [ISSN] 1610-0379
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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27. Weinstein A, Nouri K, Bassiri-Tehrani S, Flores F, Jimenez G: Muir-Torre syndrome: a case of this uncommon entity. Int J Dermatol; 2006 Mar;45(3):311-3
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  • In the past, she had been treated for basal cell carcinoma (BCC) of the face; the referring physician was concerned that the new lesions might also be BCC.
  • In addition to BCC, she had been treated for breast cancer, colon cancer, and cervical cancer prior to emigrating to the USA.
  • Further details of her medical history and cancer staging were not available.
  • Her family history was significant for a sister with colon cancer and transitional cell carcinoma of the urinary bladder.
  • In addition, she had a great aunt with oral cancer and a great uncle with lung cancer.
  • On physical examination, in addition to scars from a radical mastectomy and midline abdominal laparotomy, four skin lesions were noted: two on the scalp, one on the tragus, and one on the mid-back.
  • The first lesion on the vertex of the scalp was a yellow-brown waxy papule measuring 0.6 x 0.5 cm.
  • The second lesion on the frontal scalp measured 0.8 x 0.6 cm and was red-brown with a pearly appearance and some central hyperkeratosis.
  • The tragus lesion was similar in appearance to that on the frontal scalp.
  • The lesions on the scalp and mid-back revealed lobules of sebaceous cells in the dermis with a minority of surrounding basaloid cells, consistent with a diagnosis of sebaceous adenoma (Fig. 1).
  • Although the lesion on the frontal scalp also showed sebaceous differentiation, there were a greater number of basaloid cells, some with hyperchromatic nuclei and mitotic figures; this was consistent with a diagnosis of sebaceous epithelioma (Fig. 2).
  • [MeSH-major] Breast Neoplasms / complications. Carcinoma, Basal Cell / complications. Colonic Neoplasms / complications. Skin Neoplasms / complications. Uterine Cervical Neoplasms / complications
  • [MeSH-minor] Adenoma / complications. Adenoma / genetics. Aged. Carcinoma / complications. Carcinoma / genetics. Female. Genetic Diseases, Inborn / genetics. Humans. Sebaceous Gland Neoplasms / complications. Sebaceous Gland Neoplasms / genetics. Syndrome


28. Yoon TY, Kim HJ, Kim JW, Kim MK, Lee JY: Bowen's disease concealed by purpura. J Dermatol; 2007 Jan;34(1):65-7
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  • Bowen's disease (BD) is a squamous cell carcinoma in situ characterized by a well-demarcated scaly erythematous thin plaque with an irregular outline.
  • Clinically, BD is frequently misdiagnosed as superficial basal cell carcinoma, patches of dermatitis, psoriasis, lichen planus, actinic keratosis, benign lichenoid keratosis, irritated seborrheic keratosis, viral warts, amelanotic melanoma or melanoma.
  • However, angiosarcoma has not usually been mentioned in the differential diagnosis of BD before.
  • Herein, we describe two cases of BD presenting as purpura on the scalp of the elderly with an initial clinical suspicion of angiosarcoma.
  • [MeSH-major] Bowen's Disease / complications. Purpura / complications. Scalp. Skin Neoplasms / complications
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans

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  • (PMID = 17204105.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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29. Padgett JK: Cutaneous lesions: benign and malignant. Facial Plast Surg Clin North Am; 2005 May;13(2):195-202, v
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  • Basal and squamous cell carcinoma, lentigo maligna and lentigo maligna melanoma, dermatofibrosarcoma protuberans, and Merkel cell carcinoma are malignant lesions for which surgical excision is the recommended treatment.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / surgery. Carcinoma, Merkel Cell / diagnosis. Carcinoma, Merkel Cell / surgery. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / surgery. Dermatofibrosarcoma / diagnosis. Dermatofibrosarcoma / surgery. Humans. Hutchinson's Melanotic Freckle / diagnosis. Hutchinson's Melanotic Freckle / surgery. Nevus, Pigmented / diagnosis. Nevus, Pigmented / surgery. Risk Factors. Scalp. Sunlight / adverse effects

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  • (PMID = 15817400.001).
  • [ISSN] 1064-7406
  • [Journal-full-title] Facial plastic surgery clinics of North America
  • [ISO-abbreviation] Facial Plast Surg Clin North Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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30. Bozkurt M, Kapi E, Kuvat SV, Ozekinci S: Current concepts in the management of Marjolin's ulcers: outcomes from a standardized treatment protocol in 16 cases. J Burn Care Res; 2010 Sep-Oct;31(5):776-80
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  • Marjolin's ulcer is a malignant lesion observed in chronic wounds and in areas where the integrity of the skin is compromised because of any one of several reasons.
  • Primary lesions were at the leg, gluteal region, thigh, scalp, trunk, and hand in four (25%), three (18.7%), two (12.5%), two (12.5%), three (18.7%), and two (12.5%) cases, respectively.
  • Amputation was carried out to treat two cases, and repair of the defects with partial-thickness skin grafting was performed in 14 cases after tumor resection on the skin.
  • Squamous cell carcinoma was diagnosed in 14 cases (87.5%) and basal cell carcinoma in two cases (12.5%) postoperatively.
  • The authors conclude that diagnosis and surgical planning based on the recent literature must be carried out even more intensively to improve the prognosis of Marjolin's ulcer.
  • [MeSH-major] Burns / complications. Carcinoma, Basal Cell / etiology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / surgery. Skin Neoplasms / etiology. Skin Neoplasms / surgery. Skin Ulcer / etiology. Skin Ulcer / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Amputation. Female. Humans. Lymph Node Excision. Male. Middle Aged. Neoplasm Recurrence, Local. Skin Transplantation. Treatment Outcome

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  • (PMID = 20661151.001).
  • [ISSN] 1559-0488
  • [Journal-full-title] Journal of burn care & research : official publication of the American Burn Association
  • [ISO-abbreviation] J Burn Care Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Tellechea O, Reis JP: Trichogerminoma. Am J Dermatopathol; 2009 Jul;31(5):480-3
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  • A 45-year-old man presented with an asymptomatic nodule on the scalp since 3 years.
  • [MeSH-major] Hair Diseases / pathology. Hair Follicle / pathology. Neoplasms, Adnexal and Skin Appendage / pathology. Scalp / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Keratins / metabolism. Male. Middle Aged. Skin Neoplasms / pathology

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  • (PMID = 19542926.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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32. Yus ES, del Cerro M, Simón RS, Herrera M, Rueda M: Unna's and Miescher's nevi: two different types of intradermal nevus: hypothesis concerning their histogenesis. Am J Dermatopathol; 2007 Apr;29(2):141-51
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  • Only on the scalp was there no clear predominance of one type of intradermal nevus.
  • Miescher's nevi had more: pilosebaceous follicles within the nevus (100% versus 51%), subnevis folliculitis (12% versus 1%), large isolated melanocytes along the basal epidermal layer (47% versus 11%), multinucleated nevocytes (89% versus 44%), and adipocytes within the nevus (53% versus 11%).
  • [MeSH-major] Nevus, Intradermal / pathology. Nevus, Pigmented / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Child. Diagnosis, Differential. Female. Fibroma / pathology. Humans. Male. Melanoma / pathology. Middle Aged

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  • (PMID = 17414435.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Barcelos AC, Nico MM: Bazex-Dupré-Christol syndrome in a 1-year-old boy and his mother. Pediatr Dermatol; 2008 Jan-Feb;25(1):112-3
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  • Bazex-Dupré-Christol syndrome is a rare genodermatosis with cancer predisposition, characterized by follicular atrophoderma, multiple milia, congenital hypotrichosis, hypohidrosis and basal cell malformations that include nevoid basal cell carcinomas of early onset.
  • We present two patients with this syndrome, a 1-year-old boy with diffuse scalp and eyebrows alopecia, milia papules on the face, ears, trunk, and limbs.
  • She also had a basal cell carcinoma on her face.
  • [MeSH-major] Basal Cell Nevus Syndrome / genetics. Carcinoma, Basal Cell / pathology. Heterozygote. Precancerous Conditions / pathology. Skin Neoplasms / genetics
  • [MeSH-minor] Acrodermatitis / diagnosis. Acrodermatitis / genetics. Adolescent. Cell Transformation, Neoplastic. Female. Humans. Hypohidrosis / diagnosis. Hypohidrosis / genetics. Hypotrichosis / diagnosis. Hypotrichosis / genetics. Infant. Male. Mothers. Pedigree. Prognosis. Syndrome

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  • (PMID = 18304168.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Premalata CS, Kumar RV, Malathi M, Shenoy AM, Nanjundappa N: Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus. Int J Dermatol; 2007 Mar;46(3):306-8
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  • A 54-year-old man presented with a recurrent swelling on the right occipital region of the scalp.
  • The specimen of the initial surgery consisted of skin-covered tissue with an exophytic firm growth measuring 6 x 5 x 4 cm.
  • The skin surface was rough with areas of ulceration.
  • One was a well-circumscribed tumor located in the superficial dermis with lobules of basaloid cell aggregates with peripheral palisading and with no epidermal connection.
  • Unlike basal cell carcinoma, however, no cleft between the cellular aggregates and stroma was noted.
  • Foci of pigmentation were seen within cellular lobules and these features were consistent with a diagnosis of tricho-blastoma.
  • The third lesion was a spindle cell sarcoma which formed the major part of the lesion, diffusely infiltrating the dermis and subcutaneous tissue, elevating and ulcerating the overlying skin.
  • The wide excision specimen of the recurrent swelling consisted of a skin-covered nodule with ulceration, measuring 3 x 4 x 3 cm, with a gray-white whorled cut surface.
  • Multiple sections showed only spindle cell sarcoma infiltrating the skin and subcutaneous tissue, morphologically similar to the earlier tumor, with ulceration of the overlying skin.
  • Immunohistochemical stains on the spindle cell sarcoma showed positive staining for smooth muscle actin (SMA) (Fig.
  • Correlating the histomorphology and immunohistochemical findings, a diagnosis of cutaneous leiomyosarcoma with tricho-blastoma and syringocystadenoma papilliferum arising on nevus sebaceus was made.
  • The patient received postoperative radiotherapy and is disease free 8 months after diagnosis.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Nevus / pathology. Scalp. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


35. Chaichamnan K, Satayasoontorn K, Puttanupaab S, Attainsee A: Malignant proliferating trichilemmal tumors with CD34 expression. J Med Assoc Thai; 2010 Nov;93 Suppl 6:S28-34
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  • Malignant proliferating trichilemmal tumors (MPTT) are rare neoplasm arising from outer root sheath of hair follicle, the diagnosis of which is base essentially on histological features resulting in occasionally misdiagnosis of squamous cell carcinoma.
  • In difficult cases, however evaluation of additional parameters may be needed to differentiate benign proliferating trichilemmal tumor from MPTT or differentiate PTT and MPTT from squamous cell carcinoma.
  • For comparison, concurrent proliferating trichilemmal tumors (PTT) and trichilemmal cysts (TC) as well as well-differentiated squamous cell carcinoma (SCC) were studied.
  • The PTTs and TCs stained negative and few basal cells for p53 and Ki-67, respectively.
  • The contrast p53 and Ki-67 expression pattern in MPTT and PTT may be helpful in the diagnosis of MPTT.
  • [MeSH-major] Antigens, CD34 / metabolism. Carcinoma, Squamous Cell / metabolism. Epidermal Cyst / pathology. Hair Follicle / pathology. Scalp / pathology. Skin Neoplasms / pathology. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Recurrence, Local. Treatment Outcome

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  • (PMID = 21280514.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Tumor Suppressor Protein p53
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36. Scholz IM, Nümann A, Froster UG, Helmbold P, Enk AH, Näher H: New mutation in the CYLD gene within a family with Brooke-Spiegler syndrome. J Dtsch Dermatol Ges; 2010 Feb;8(2):99-101
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  • Brooke-Spiegler syndrome is a rare, autosomal dominant disease characterized by multiple skin appendage tumors caused by various mutations in the CYLD gene on chromosome 16q12-q13.
  • In addition, there may be malignant transformation of the generally benign tumors, so that a timely diagnosis is essential for appropriate monitoring and therapy.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. DNA Mutational Analysis. Facial Neoplasms / genetics. Frameshift Mutation. Neoplasms, Multiple Primary / genetics. Scalp. Skin Neoplasms / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adenoma, Sweat Gland / diagnosis. Adenoma, Sweat Gland / genetics. Adenoma, Sweat Gland / pathology. Adolescent. Adult. Biopsy. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / genetics. Carcinoma, Basal Cell / pathology. Chromosome Aberrations. Chromosomes, Human, Pair 16 / genetics. Exons / genetics. Female. Genes, Dominant / genetics. Humans. Male. Middle Aged. Nose Neoplasms / genetics. Nose Neoplasms / pathology. Phenotype. Skin / pathology. Syndrome

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  • (PMID = 20151946.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CYLD protein, human; 0 / Tumor Suppressor Proteins
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37. Tran H, Bossenbroek NM, Rosenman K, Meehan SA, Sanchez M, Prystowsky S: Steroid-responsive facial eruption with cornoid lamellae--a possible new entity. Dermatol Online J; 2008;14(10):9
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  • The histopathologic presence of a cornoid lamella is often associated with a diagnosis of porokeratosis.
  • However, this feature is not pathognomonic for porokeratosis and can be found in a number of other dermatologic conditions, which include seborrheic keratosis, verruca vulgaris, actinic keratosis, squamous-cell carcinoma in situ, basal-cell carcinoma, milia, and scar.
  • [MeSH-major] Facial Dermatoses / pathology. Scalp Dermatoses / pathology. Skin Diseases, Papulosquamous / pathology
  • [MeSH-minor] Anti-Inflammatory Agents / therapeutic use. Antiviral Agents / therapeutic use. Diagnosis, Differential. Glucocorticoids / therapeutic use. Hepatitis C / drug therapy. Humans. Inflammation. Interferon-alpha / therapeutic use. Male. Middle Aged. Polyethylene Glycols. Porokeratosis / diagnosis. Recombinant Proteins

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  • (PMID = 19061608.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Antiviral Agents; 0 / Glucocorticoids; 0 / Interferon-alpha; 0 / Recombinant Proteins; 0 / peginterferon alfa-2b; 30IQX730WE / Polyethylene Glycols; 99210-65-8 / interferon alfa-2b
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38. Puri PK, Galan A, Glusac EJ, Cowper SE: Metastatic cutaneous carcinoid tumor mimicking an adnexal poroid neoplasm. J Cutan Pathol; 2008 Jan;35(1):54-7
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  • METHODS: A 53-year-old male man presented with a neoplasm on the vertex of the scalp, clinically resembling a pigmented basal cell carcinoma.
  • RESULTS: A shave biopsy was suggestive of an apocrine poroma, however, a metastatic carcinoma could not be excluded.
  • After acquiring additional clinical information and the complete excision of the neoplasm, further immunohistochemical stains supported the diagnosis a metastatic carcinoid tumor.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Carcinoid Tumor / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18095995.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Abedalthagafi M, Rushing EJ, Auerbach A, Desouki MM, Marwaha J, Wang Z, Fanburg-Smith JC: Sporadic cutaneous angiosarcomas generally lack hypoxia-inducible factor 1alpha: a histologic and immunohistochemical study of 45 cases. Ann Diagn Pathol; 2010 Feb;14(1):15-22
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  • Tumors presented most commonly in the skin of the scalp followed by the left lower leg, face, nose, lower arm, neck, thigh, eyelid, ear, and temple.
  • Associated basal cell carcinoma was noted in 1 patient; no others had other neoplasms or unrelated surgeries.
  • Cutaneous angiosarcoma is largely found on the scalp of older individuals.
  • Requirement for diagnosis includes extravascular proliferation of atypical endothelial cells with mitotic activity in vasoformative, solid, and papillary patterns.
  • [MeSH-major] Dermis / metabolism. Hemangiosarcoma / metabolism. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Neovascularization, Pathologic / metabolism. Skin Neoplasms / metabolism

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20123452.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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40. Watkins J: Dermatology and the community nurse: actinic (solar) keratosis. Br J Community Nurs; 2010 Jan;15(1):6, 8, 10-1
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  • They are then able to check other sun-exposed areas such as the face, ears, scalp, back and limbs to discover any other lesions or more serious problems of basal cell carcinoma, squamous cell carcinoma or malignant melanoma the would require referral, sometimes urgently, to a dermatologist for full assessment and treatment.
  • [MeSH-major] Keratosis / nursing. Skin Neoplasms / nursing. Sunlight / adverse effects
  • [MeSH-minor] Community Health Nursing. Diagnosis, Differential. Humans. Nursing Diagnosis. Protective Clothing. Risk Factors. Sunscreening Agents

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  • (PMID = 20216512.001).
  • [ISSN] 1462-4753
  • [Journal-full-title] British journal of community nursing
  • [ISO-abbreviation] Br J Community Nurs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sunscreening Agents
  • [Number-of-references] 13
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41. Walsh SN, Hurt MA, Santa Cruz DJ: Psoriasiform keratosis. Am J Dermatopathol; 2007 Apr;29(2):137-40
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  • There was, however, no known clinical diagnosis of psoriasis in any patient, neither at initial presentation nor on follow-up examination.
  • Other sites included the scalp, neck, shoulders, and back.
  • The mean age at diagnosis was 66.8 years.
  • The most common diagnoses, clinically, were seborrheic keratosis, followed by basal cell carcinoma, Bowen's disease, actinic (solar) keratosis, and squamous cell carcinoma, among others.
  • [MeSH-major] Keratosis, Seborrheic / pathology. Psoriasis / pathology. Skin / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Lichenoid Eruptions / pathology. Lymphocytes / pathology. Male. Middle Aged. Neutrophils / pathology. Prospective Studies. Terminology as Topic. Time Factors

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  • (PMID = 17414434.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Caccialanza M, Piccinno R, Percivalle S, Gnecchi L: Successful use of radiotherapy for radiation-induced basal cell carcinoma of the scalp. Clin Exp Dermatol; 2008 Aug;33(5):660-1
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  • [Title] Successful use of radiotherapy for radiation-induced basal cell carcinoma of the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / radiotherapy. Head and Neck Neoplasms / radiotherapy. Neoplasms, Radiation-Induced / radiotherapy. Scalp. Skin Neoplasms / radiotherapy

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  • [CommentOn] Clin Exp Dermatol. 2007 Jan;32(1):109-11 [17305917.001]
  • (PMID = 18616720.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] England
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43. Chuo CB, Slator R, Brown RM, Anderson KD: Management of desmoplastic trichoepithelioma in an infant. J Plast Reconstr Aesthet Surg; 2008 Oct;61(10):1241-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma / pathology. Head and Neck Neoplasms / pathology. Scalp / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Facial Neoplasms / pathology. Female. Humans. Infant. Infant, Newborn. Syringoma / pathology

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  • (PMID = 18554999.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Netherlands
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