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1. Kokcam I, Saki CE: A case of cutaneous myiasis caused by Wohlfahrtia magnifica. J Dermatol; 2005 Jun;32(6):459-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 46-year-old male farmer with nevoid basal cell carcinoma syndrome (NBCCS) presented with the complaint of a blood-tinged discharge and pain in the left frontal-temporal region for three days.
  • Physical examination revealed live maggots in the ulcerous wound resulting from basal cell carcinoma.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Diptera / parasitology. Myiasis / diagnosis. Skin Diseases, Parasitic / diagnosis. Skin Neoplasms / pathology
  • [MeSH-minor] Agriculture. Animals. Face. Follow-Up Studies. Humans. Larva. Male. Middle Aged. Risk Assessment. Scalp. Treatment Outcome. Turkey

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  • (PMID = 16043920.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 22
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2. Nakai N, Takenaka H, Hamada S, Kishimoto S: Identical p53 gene mutation in malignant proliferating trichilemmal tumour of the scalp and small cell carcinoma of the common bile duct: the necessity for therapeutic caution? Br J Dermatol; 2008 Aug;159(2):482-5
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  • [Title] Identical p53 gene mutation in malignant proliferating trichilemmal tumour of the scalp and small cell carcinoma of the common bile duct: the necessity for therapeutic caution?
  • [MeSH-major] Genes, p53. Head and Neck Neoplasms / genetics. Neoplasms, Basal Cell / genetics. Point Mutation. Scalp. Skin Neoplasms / genetics

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  • (PMID = 18510672.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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3. Satter EK, Derienzo DP: Synchronous onset of multiple cutaneous neuroendocrine (Merkel cell) carcinomas localized to the scalp. J Cutan Pathol; 2008 Jul;35(7):685-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous onset of multiple cutaneous neuroendocrine (Merkel cell) carcinomas localized to the scalp.
  • Merkel cell carcinoma (MCC) is a rare aggressive neoplasm that typically presents as a solitary nodule or plaque on sun-exposed skin of the elderly.
  • We report a case of a 59-year-old white male who presented with abrupt onset of multiple small bluish papules on his frontal scalp.
  • On low power, the tumor had the overall histological silhouette of a nodular basal cell carcinoma.
  • However, because of the lack of an epithelial connection and the cell's cytomorphological features, a MCC was considered and was subsequently confirmed using immunohistochemical stains.
  • [MeSH-major] Carcinoma, Merkel Cell / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Lymph Nodes / pathology. Lymphatic Metastasis. Male. Middle Aged. Scalp / pathology

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  • (PMID = 18331571.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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4. Kandamany N, Monk B: Basal cell carcinoma presenting late in a shotgun scar. Am J Clin Dermatol; 2009;10(4):271-2
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  • [Title] Basal cell carcinoma presenting late in a shotgun scar.
  • The development of a basal cell carcinoma (BCC) as a late complication of a shotgun injury is a rare clinical entity.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Cicatrix / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Scalp / injuries. Scalp / pathology. Wounds, Gunshot / pathology

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  • (PMID = 19489662.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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5. Yus ES, del Cerro M, Simón RS, Herrera M, Rueda M: Unna's and Miescher's nevi: two different types of intradermal nevus: hypothesis concerning their histogenesis. Am J Dermatopathol; 2007 Apr;29(2):141-51
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  • Only on the scalp was there no clear predominance of one type of intradermal nevus.
  • Miescher's nevi had more: pilosebaceous follicles within the nevus (100% versus 51%), subnevis folliculitis (12% versus 1%), large isolated melanocytes along the basal epidermal layer (47% versus 11%), multinucleated nevocytes (89% versus 44%), and adipocytes within the nevus (53% versus 11%).
  • [MeSH-major] Nevus, Intradermal / pathology. Nevus, Pigmented / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Child. Diagnosis, Differential. Female. Fibroma / pathology. Humans. Male. Melanoma / pathology. Middle Aged

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  • (PMID = 17414435.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Krahl D, Sellheyer K: Sox9, more than a marker of the outer root sheath: spatiotemporal expression pattern during human cutaneous embryogenesis. J Cutan Pathol; 2010 Mar;37(3):350-6
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  • It was also characterized as a general marker of basal cell carcinoma.
  • METHODS: We examined immunohistochemically samples from embryonic and fetal human skin for the expression of SOX9 using standard techniques.
  • For comparison reasons, we also included scalp skin from adults.
  • In plantar skin, SOX9 specifically labels the evolving eccrine glands but not the interfollicular keratinocytes.
  • CONCLUSIONS: The distinctive expression pattern of SOX9 during human cutaneous embryogenesis indicates a key role in skin homeostasis that includes but goes beyond its role in outer root sheath differentiation.
  • Studying immunohistochemical markers in developing human skin has the potential to further our understanding of adult skin physiology and to deepen our concepts especially of the histogenesis of adnexal tumors (including those of the nail unit) and the relationship of the various adnexal structures to each other.
  • [MeSH-major] Hair Follicle / embryology. Nails / embryology. SOX9 Transcription Factor / metabolism. Skin / embryology
  • [MeSH-minor] Adult. Cell Proliferation. Gene Expression Regulation, Developmental. Humans. Immunohistochemistry

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  • (PMID = 19614725.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / SOX9 Transcription Factor; 0 / SOX9 protein, human
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7. Leibovitch I, Huilgol SC, Selva D, Richards S, Paver R: Basal cell carcinoma treated with Mohs surgery in Australia II. Outcome at 5-year follow-up. J Am Acad Dermatol; 2005 Sep;53(3):452-7
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  • [Title] Basal cell carcinoma treated with Mohs surgery in Australia II. Outcome at 5-year follow-up.
  • BACKGROUND: Long-term follow-up is essential to evaluate the role of Mohs micrographic surgery (MMS) in the treatment for cutaneous basal cell carcinoma (BCC).
  • METHOD: This prospective, multicenter case series included all patients in Australia treated with MMS for BCC, who were monitored by the Skin and Cancer Foundation between 1993 and 2002.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Head and Neck Neoplasms / surgery. Mohs Surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Australia. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nose Neoplasms / surgery. Prospective Studies. Scalp. Treatment Outcome


8. Wang SQ, Goldberg LH: Pulsed dye laser for the treatment of hypergranulation tissue with chronic ulcer in postsurgical defects. J Drugs Dermatol; 2007 Dec;6(12):1191-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The majority of the wounds were located on the scalp, forehead, and temple.
  • [MeSH-major] Granulation Tissue / surgery. Laser Therapy. Lasers, Dye / therapeutic use. Mohs Surgery. Postoperative Complications / surgery. Skin Ulcer / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Female. Humans. Male. Melanoma / surgery. Middle Aged. Neoplasms, Squamous Cell / surgery. Retrospective Studies. Skin Neoplasms / surgery. Wound Healing

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  • (PMID = 18189058.001).
  • [ISSN] 1545-9616
  • [Journal-full-title] Journal of drugs in dermatology : JDD
  • [ISO-abbreviation] J Drugs Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Goldberg LH, Kimyai-Asadi A: Diffuse epidermal and periadnexal squamous cell carcinoma in situ: a report of 13 patients. J Am Acad Dermatol; 2005 Oct;53(4):623-7
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  • [Title] Diffuse epidermal and periadnexal squamous cell carcinoma in situ: a report of 13 patients.
  • BACKGROUND: Diffuse epidermal and periadnexal squamous cell carcinoma in situ (DEPS) is a condition in which large areas of skin are affected by atypical keratinocytes that grow beneath the epidermis and encase adnexal epithelia.
  • The lesions were present on the scalp, face, and neck.
  • In the 52 cumulative patient-years of follow-up, we treated 80 invasive squamous cell and 48 basal cell carcinomas in these patients.
  • CONCLUSION: DEPS is characterized by diffuse involvement of chronically sun-exposed skin with atypical keratinocytes that grow along the inferior portion of the basal layer of the epidermis and around adnexal structures.
  • DEPS is also associated with the development of invasive squamous cell and basal cell carcinomas.
  • [MeSH-major] Carcinoma in Situ / pathology. Carcinoma, Squamous Cell / pathology. Epidermis / pathology. Facial Neoplasms / pathology. Keratinocytes / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Humans. Male. Middle Aged. Retrospective Studies. Scalp

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  • (PMID = 16198782.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Watkins J: Dermatology and the community nurse: actinic (solar) keratosis. Br J Community Nurs; 2010 Jan;15(1):6, 8, 10-1
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  • They are then able to check other sun-exposed areas such as the face, ears, scalp, back and limbs to discover any other lesions or more serious problems of basal cell carcinoma, squamous cell carcinoma or malignant melanoma the would require referral, sometimes urgently, to a dermatologist for full assessment and treatment.
  • [MeSH-major] Keratosis / nursing. Skin Neoplasms / nursing. Sunlight / adverse effects
  • [MeSH-minor] Community Health Nursing. Diagnosis, Differential. Humans. Nursing Diagnosis. Protective Clothing. Risk Factors. Sunscreening Agents

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  • (PMID = 20216512.001).
  • [ISSN] 1462-4753
  • [Journal-full-title] British journal of community nursing
  • [ISO-abbreviation] Br J Community Nurs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sunscreening Agents
  • [Number-of-references] 13
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11. Moloney FJ, Comber H, O'Lorcain P, O'Kelly P, Conlon PJ, Murphy GM: A population-based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol; 2006 Mar;154(3):498-504
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A population-based study of skin cancer incidence and prevalence in renal transplant recipients.
  • OBJECTIVES: To determine the incidence of all cancers following renal transplantation and to make a detailed examination of trends and patterns associated with postrenal transplant skin cancers.
  • METHODS: Integration of data from the national renal transplant database and the national cancer registry in Ireland enabled accurate determination of the number of renal transplant recipients (RTRs) with skin cancers and other malignancies in the time period 1 January 1994 to 31 December 2001.
  • RESULTS: We demonstrated a biphasic increase in skin cancer incidence following renal transplantation, determined by the age at transplantation.
  • The number of nonmelanoma skin cancers (NMSCs) registered in RTRs accounted for 1% of all NMSCs registered nationally over the study period.
  • The standardized incidence rates for invasive NMSC (33-fold increase) and in situ carcinoma of the skin (65-fold increase) were significantly increased (P < 0.05).
  • The risk for invasive squamous cell carcinoma (SCC) was increased 82-fold compared with the nontransplanted population.
  • Male RTRs were at particular risk of invasive SCC at sun-exposed sites such as the scalp and the external ear.
  • CONCLUSIONS: This comprehensive national study illustrates how rates of skin cancer in Irish RTRs have influenced the national incidence of skin cancer.
  • The high incidence of SCC, basal cell carcinoma and Bowen's disease in the early post-transplant period for older patients and the cumulative risk in younger patients with increased duration of transplantation highlight the importance of implementing early and continued cancer surveillance regimens post-transplant.
  • [MeSH-major] Kidney Transplantation. Skin Neoplasms / epidemiology
  • [MeSH-minor] Adult. Age Factors. Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / immunology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / immunology. Epidemiologic Methods. Female. Humans. Immunocompromised Host. Immunosuppression / adverse effects. Ireland / epidemiology. Male. Sex Distribution


12. Scholz IM, Nümann A, Froster UG, Helmbold P, Enk AH, Näher H: New mutation in the CYLD gene within a family with Brooke-Spiegler syndrome. J Dtsch Dermatol Ges; 2010 Feb;8(2):99-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Brooke-Spiegler syndrome is a rare, autosomal dominant disease characterized by multiple skin appendage tumors caused by various mutations in the CYLD gene on chromosome 16q12-q13.
  • In addition, there may be malignant transformation of the generally benign tumors, so that a timely diagnosis is essential for appropriate monitoring and therapy.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. DNA Mutational Analysis. Facial Neoplasms / genetics. Frameshift Mutation. Neoplasms, Multiple Primary / genetics. Scalp. Skin Neoplasms / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adenoma, Sweat Gland / diagnosis. Adenoma, Sweat Gland / genetics. Adenoma, Sweat Gland / pathology. Adolescent. Adult. Biopsy. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / genetics. Carcinoma, Basal Cell / pathology. Chromosome Aberrations. Chromosomes, Human, Pair 16 / genetics. Exons / genetics. Female. Genes, Dominant / genetics. Humans. Male. Middle Aged. Nose Neoplasms / genetics. Nose Neoplasms / pathology. Phenotype. Skin / pathology. Syndrome

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  • (PMID = 20151946.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CYLD protein, human; 0 / Tumor Suppressor Proteins
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13. D'Arpa S, Cordova A, Moschella F: Further application of the bilobed flap: the split bilobed flap for reconstruction of composite posterior auricular and mastoid defects. J Plast Reconstr Aesthet Surg; 2006;59(12):1330-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this article a modified bilobed flap from mastoid and lateral neck skin for reconstruction of complex defects of the posteromedial surface of the auricle and mastoid skin, with the preservation of the retroauricular sulcus, is described.
  • It is in fact a shaded area with little aesthetic relevance and direct closure, skin grafting and even secondary healing are used for skin cancer defects repair.
  • Also mastoid skin defects can be repaired with simple techniques such as skin grafts or transposition flaps from the remaining mastoid skin or from the neck.
  • On the other hand, cancers involving the postero-medial auricular surface, the retroauricular sulcus and the mastoid skin require wide and deep resections that involve the posterior auricular muscles and reach the perichondral and periosteal surfaces.
  • Transposition flaps from the remaining mastoid skin, due to the lack of skin laxity, are not feasible because the donor site cannot be closed.
  • Two patients, both affected by basal cell carcinoma involving the posteromedial auricular surface and the mastoid skin have been treated with this flap.
  • [MeSH-major] Ear Deformities, Acquired / surgery. Ear, External / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / surgery. Ear Neoplasms / surgery. Head and Neck Neoplasms / surgery. Humans. Male. Mastoid

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  • (PMID = 17113512.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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14. Yoon TY, Kim HJ, Kim JW, Kim MK, Lee JY: Bowen's disease concealed by purpura. J Dermatol; 2007 Jan;34(1):65-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Bowen's disease (BD) is a squamous cell carcinoma in situ characterized by a well-demarcated scaly erythematous thin plaque with an irregular outline.
  • Clinically, BD is frequently misdiagnosed as superficial basal cell carcinoma, patches of dermatitis, psoriasis, lichen planus, actinic keratosis, benign lichenoid keratosis, irritated seborrheic keratosis, viral warts, amelanotic melanoma or melanoma.
  • However, angiosarcoma has not usually been mentioned in the differential diagnosis of BD before.
  • Herein, we describe two cases of BD presenting as purpura on the scalp of the elderly with an initial clinical suspicion of angiosarcoma.
  • [MeSH-major] Bowen's Disease / complications. Purpura / complications. Scalp. Skin Neoplasms / complications
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans

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  • (PMID = 17204105.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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15. Kimyai-Asadi A, Goldberg LH, Peterson SR, Silapint S, Jih MH: The incidence of major complications from Mohs micrographic surgery performed in office-based and hospital-based settings. J Am Acad Dermatol; 2005 Oct;53(4):628-34
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  • Ninety-three percent of lesions were basal cell or squamous cell carcinomas, and 86% were located on the head and neck.
  • [MeSH-major] Ambulatory Surgical Procedures / statistics & numerical data. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / surgery. Mohs Surgery / adverse effects. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Ear Neoplasms / surgery. Female. Hemostasis, Surgical. Hospitals, Teaching. Humans. Lip Neoplasms / surgery. Male. Nose Neoplasms / surgery. Retrospective Studies. Scalp. Skin Transplantation. Surgical Flaps

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  • (PMID = 16198783.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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16. Tuncer S, Kuvat SV, Kabakas F, Ermis I: Expansion of skin by a lipoma and its use as a full-thickness skin graft. Plast Reconstr Surg; 2006 Mar;117(3):1058-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expansion of skin by a lipoma and its use as a full-thickness skin graft.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Head and Neck Neoplasms / surgery. Lipoma / surgery. Neoplasms, Multiple Primary / surgery. Scalp. Skin Neoplasms / surgery. Skin Transplantation

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  • (PMID = 16525329.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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17. Findley AB, Pride H: Unusual cystic scalp lesions in Gorlin syndrome: a brief report. Pediatr Dermatol; 2010 Mar-Apr;27(2):204-7
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  • [Title] Unusual cystic scalp lesions in Gorlin syndrome: a brief report.
  • Nevoid basal cell carcinoma syndrome (Gorlin syndrome) is a rare, autosomal dominant syndrome that is known to have variable expressivity in multiple organ systems.
  • We describe the case of a young male child with nevoid basal cell carcinoma syndrome and scalp lesions, including a branchial cleft cyst with respiratory epithelium and a rudimentary meningocele.
  • These are both new, previously unreported findings, possibly associated with nevoid basal cell carcinoma syndrome.
  • [MeSH-major] Basal Cell Nevus Syndrome / diagnosis. Branchioma / diagnosis. Head and Neck Neoplasms / diagnosis. Scalp. Skin Neoplasms / diagnosis


18. Leibovitch I, Huilgol SC, Richards S, Paver R, Selva D: Scalp tumors treated with Mohs micrographic surgery: clinical features and surgical outcome. Dermatol Surg; 2006 Nov;32(11):1369-74
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  • [Title] Scalp tumors treated with Mohs micrographic surgery: clinical features and surgical outcome.
  • BACKGROUND: There are only a small number of reports on the outcome of scalp tumors treated with Mohs micrographic surgery (MMS).
  • OBJECTIVE: The objective was to present a large series of patients with scalp tumors treated with MMS in Australia between 1993 and 2002.
  • METHODS: This prospective, multicenter study included all patients with scalp tumors who were monitored by the Skin and Cancer Foundation Australia.
  • The most common tumors were basal cell carcinoma (BCC), 57.9%; squamous cell carcinoma (SCC), 35.8%; Bowen's disease (BD), 4.1%; and atypical fibroxanthoma (AFX), 1.6%.
  • CONCLUSION: BCC was the most common scalp tumor managed by MMS.
  • The low 5-year recurrence rate emphasizes the importance of margin controlled excision of scalp tumors.
  • [MeSH-major] Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / surgery. Scalp. Skin Neoplasms / epidemiology. Skin Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Australia / epidemiology. Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / etiology. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Middle Aged. Mohs Surgery. Prospective Studies. Treatment Outcome


19. Suissa D: Basal cell carcinoma and therapeutic radiation in childhood: methodological issues. Ann Plast Surg; 2007 May;58(5):589; author reply 589-90
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  • [Title] Basal cell carcinoma and therapeutic radiation in childhood: methodological issues.
  • [MeSH-major] Carcinoma, Basal Cell / etiology. Neoplasms, Radiation-Induced. Scalp / radiation effects. Skin Neoplasms / etiology

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  • [CommentOn] Ann Plast Surg. 2006 Nov;57(5):509-12 [17060730.001]
  • (PMID = 17452854.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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20. Scott AR, Faquin WC, Deschler DG: Parotid mass in a woman with multiple cutaneous cylindromas. Head Neck; 2010 May;32(5):684-7
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  • We present a case of a woman with scalp lesions and a parotid mass.
  • METHODS: Biopsy of a skin nodule demonstrated cylindroma, and fine-needle aspiration of the parotid mass suggested membranous basal cell adenoma, which was confirmed following superficial parotidectomy.
  • RESULTS: Eighteen cases of cylindromatosis with coexistent salivary gland membranous basal cell adenoma were reported.
  • Membranous basal cell adenoma may be mistaken for adenoid cystic carcinoma on cytologic or histologic examination.
  • [MeSH-major] Adenoma / pathology. Carcinoma, Adenoid Cystic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 19455704.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Baykal C, Buyukbabani N, Yazganoglu KD, Saglik E: [Tumors associated with nevus sebaceous]. J Dtsch Dermatol Ges; 2006 Jan;4(1):28-31
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  • BACKGROUND: Nevus sebaceus (NS) is a congenital hamartomatous lesion, usually involving the scalp or the face.
  • Various benign and malignant neoplasms can develop in association with NS, the most common being trichoblastoma, syringocystadenoma papilliferum, viral warts and basal cell carcinoma (BCC).
  • CONCLUSION: Clinical features are not sufficient enough to make an exact diagnosis of benign or malignant secondary tumors.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Second Primary / diagnosis. Nevus / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Facial Neoplasms / diagnosis. Facial Neoplasms / pathology. Female. Humans. Male. Middle Aged. Scalp / pathology. Skin / pathology


22. Hassanpour SE, Kalantar-Hormozi A, Motamed S, Moosavizadeh SM, Shahverdiani R: Basal cell carcinoma of scalp in patients with history of childhood therapeutic radiation: a retrospective study and comparison to nonirradiated patients. Ann Plast Surg; 2006 Nov;57(5):509-12
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  • [Title] Basal cell carcinoma of scalp in patients with history of childhood therapeutic radiation: a retrospective study and comparison to nonirradiated patients.
  • BACKGROUND: Basal cell carcinoma (BCC) is the most common human malignant neoplasm.
  • Some patients with scalp BCC have had a history of childhood scalp radiation for the treatment of tinea capitis.
  • MATERIALS AND METHODS: From 1995 to 2005, a total of 74 patients were diagnosed with scalp BCC.
  • Thirty-eight patients (group A) had a history of childhood radiation to the scalp for the treatment of tinea capitis, and the other 36 (group B) did not.
  • Patients in group A had a longer history of scalp lesions (P = 0.001).
  • CONCLUSION: BCC in irradiated scalp has a more aggressive behavior and may need a more aggressive surgical resection.
  • Also, these patients should be under close observation because there is a higher chance for tumor recurrence and also new lesions occurring elsewhere in the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / radiotherapy. Carcinoma, Basal Cell / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / radiotherapy. Skin Neoplasms / surgery. Survivors / statistics & numerical data
  • [MeSH-minor] Adult. Aged. Child. Female. Humans. Male. Middle Aged. Retrospective Studies. Scalp. Treatment Outcome

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  • [CommentIn] Ann Plast Surg. 2007 May;58(5):589; author reply 589-90 [17452854.001]
  • (PMID = 17060730.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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23. Kantrow SM, Boyd AS: Primary cutaneous metaplastic carcinoma: report of a case involving angiosarcoma. Am J Dermatopathol; 2007 Jun;29(3):270-3
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  • [Title] Primary cutaneous metaplastic carcinoma: report of a case involving angiosarcoma.
  • Primary cutaneous metaplastic carcinoma is an uncommon cutaneous malignancy comprising a mixture of epithelial and mesenchymal components.
  • The former is most frequently a squamous cell or basal cell carcinoma, and the latter is most typically a pleomorphic sarcoma or atypical fibroxanthoma.
  • We describe the first primary cutaneous metaplastic carcinoma with angiosarcoma as the mesenchymal component arising on the scalp of a 90-year-old woman.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Carcinosarcoma / pathology. Hemangiosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

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  • (PMID = 17519625.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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24. Sellheyer K, Krahl D: Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin. J Am Acad Dermatol; 2010 Jul;63(1):93-113
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  • [Title] Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin.
  • OBJECTIVE: Because the neuroepithelial stem cell marker nestin represents a marker for mesenchymal stem cells in various tissues, our aim was to characterize its spatiotemporal expression pattern in the skin with special reference to the follicular mesenchyme.
  • METHODS: We studied immunohistochemically nestin expression over the course of human cutaneous embryogenesis, in postnatal skin, in scalp wounds, and in the peritumoral stroma of basal cell carcinomas and compared its expression with that of other known mesenchymal markers.
  • Its expression is up-regulated in scalp wounds and the nestin-positive cells seem to originate from the follicular mesenchyme.
  • Nestin is also expressed in a thin layer of fibroblasts in the immediate vicinity of basal cell carcinomas.
  • LIMITATIONS: The examination for nestin expression of scalp wounds is considered preliminary, because we examined scalp wounds representing re-excisions of previously diagnosed neoplasms from which we had no exact time table available as to when the original excision took place.
  • CONCLUSION: We propose that nestin functions as a stem cell marker of the follicular mesenchyme and has a major regulatory role in dermal homeostasis, cutaneous neovasculogenesis, and tumor stroma development.
  • [MeSH-major] Biomarkers / analysis. Homeostasis / physiology. Intermediate Filament Proteins / analysis. Mesenchymal Stromal Cells / chemistry. Neovascularization, Physiologic / physiology. Nerve Tissue Proteins / analysis. Skin / blood supply. Skin Physiological Phenomena
  • [MeSH-minor] Adult. Blood Vessels / chemistry. Carcinoma, Basal Cell / chemistry. Fibroblasts / chemistry. Hair Follicle / chemistry. Humans. Immunohistochemistry. Keratinocytes / chemistry. Nestin. Scalp / cytology. Scalp / injuries. Skin Neoplasms. Up-Regulation


25. Tran H, Bossenbroek NM, Rosenman K, Meehan SA, Sanchez M, Prystowsky S: Steroid-responsive facial eruption with cornoid lamellae--a possible new entity. Dermatol Online J; 2008;14(10):9
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  • The histopathologic presence of a cornoid lamella is often associated with a diagnosis of porokeratosis.
  • However, this feature is not pathognomonic for porokeratosis and can be found in a number of other dermatologic conditions, which include seborrheic keratosis, verruca vulgaris, actinic keratosis, squamous-cell carcinoma in situ, basal-cell carcinoma, milia, and scar.
  • [MeSH-major] Facial Dermatoses / pathology. Scalp Dermatoses / pathology. Skin Diseases, Papulosquamous / pathology
  • [MeSH-minor] Anti-Inflammatory Agents / therapeutic use. Antiviral Agents / therapeutic use. Diagnosis, Differential. Glucocorticoids / therapeutic use. Hepatitis C / drug therapy. Humans. Inflammation. Interferon-alpha / therapeutic use. Male. Middle Aged. Polyethylene Glycols. Porokeratosis / diagnosis. Recombinant Proteins

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  • (PMID = 19061608.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Antiviral Agents; 0 / Glucocorticoids; 0 / Interferon-alpha; 0 / Recombinant Proteins; 0 / peginterferon alfa-2b; 30IQX730WE / Polyethylene Glycols; 99210-65-8 / interferon alfa-2b
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26. Feito-Rodríguez M, González-Beato MJ, Pizarro A: [Unusual vascular pattern of a nodular lesion in the dermoscopic examination of a kidney transplant recipient]. Actas Dermosifiliogr; 2008 May;99(4):307-8
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  • [MeSH-major] Carcinoma, Basal Cell / pathology. Kidney Transplantation. Scalp. Skin Neoplasms / pathology

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  • (PMID = 18394409.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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27. Fattah A, Pollock J, Maheshwar A, Britto JA: Big Bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinomata. J Plast Reconstr Aesthet Surg; 2010 May;63(5):e433-41
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  • [Title] Big Bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinomata.
  • Basal cell carcinoma (BCC) is the most common malignancy of the body and most frequently occurs in the head and neck.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Face / surgery. Head and Neck Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Scalp. Skin Neoplasms / surgery. Skull / surgery

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  • [Copyright] Copyright (c) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19879202.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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28. Eugene DW, Joshi KD: Xeroderma pigmentosa--a disfiguring disease. Kathmandu Univ Med J (KUMJ); 2006 Jan-Mar;4(1):78-81
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  • Kunwar et al. Those affected are extremely sensitive to the UV portion of the light and have a 2000-fold increased risk of skin cancer in the sun exposed skin.
  • Basal cell carcinoma is the most commonly associated carcinoma followed by Squamous cell carcinoma and Melanoma.
  • The recurring cancer occurring on the face and repeated surgical treatment for the ulcerations have important social and psychological implications not encountered with other cancers.
  • The second case presented with melanoma of the scalp in a 10 year old female child.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Melanoma / pathology. Skin Neoplasms / pathology. Xeroderma Pigmentosum / pathology

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  • (PMID = 18603874.001).
  • [ISSN] 1812-2027
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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29. Wilensky JS, Rosenthal AH, Bradford CR, Rees RS: The use of a bovine collagen construct for reconstruction of full-thickness scalp defects in the elderly patient with cutaneous malignancy. Ann Plast Surg; 2005 Mar;54(3):297-301
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  • [Title] The use of a bovine collagen construct for reconstruction of full-thickness scalp defects in the elderly patient with cutaneous malignancy.
  • Full-thickness defects of the scalp following cancer resection are reconstructive challenges when bone is exposed.
  • Thereafter, delayed skin grafting was performed.
  • All patients had one of the following: melanoma (n = 13) squamous cell carcinoma (n = 5), angiosarcoma (n = 2), basal cell carcinoma (n = 1), spindle cell carcinoma (n = 1), or malignant pilar tumor (n = 1).
  • Average time between bovine construct placement and skin grafting was 30 days.
  • In the elderly, this is a simple method to treat full-thickness scalp defects.
  • [MeSH-major] Biocompatible Materials. Collagen. Head and Neck Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Skin Neoplasms / surgery. Skin Transplantation. Skin, Artificial

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  • (PMID = 15725839.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / integra artificial skin; 9007-28-7 / Chondroitin Sulfates; 9007-34-5 / Collagen
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30. Scheinfeld N: Review of scalp alopecia due to a clinically unapparent or minimally apparent neoplasm (SACUMAN). Acta Derm Venereol; 2006;86(5):387-92
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  • [Title] Review of scalp alopecia due to a clinically unapparent or minimally apparent neoplasm (SACUMAN).
  • Neoplastic cells, both malignant and benign, local occurring and metastatic, can cause alopecia of the scalp.
  • However, the infiltration of neoplastic cells is sometimes not florid; a condition known as "scalp alopecia due to a clinically unapparent or minimally apparent neoplasm" (SACUMAN).
  • The most common neoplasm in which an uncomplicated, minimally or unapparent scalp alopecia occurs and no infiltrate of cancer is suspected is metastatic breast carcinoma.
  • Other causes include squamous and basal cell carcinomas, angiosarcoma, gastric carcinoma, placental site tromphoblastic tumor, and mycosis fungoides.
  • In conclusion, neoplasms causing cicatricial alopecia of the scalp are very rare, so generalizations from the limited number of case reports are of uncertain importance.
  • Moreover, it is likely that many cases of neoplasms causing cicatricial alopecia of the scalp are diagnosed as inflammatory alopecia and not neoplasms, thus depriving us of a full accounting and understanding of this entity.
  • Dermatologists must be aware that in rare cases a bland scalp alopecia can represent a new or recurring, local or metastatic neoplasm.
  • [MeSH-major] Alopecia / etiology. Skin Neoplasms / pathology
  • [MeSH-minor] Breast Neoplasms / pathology. Carcinoma, Basal Cell / pathology. Cicatrix / pathology. Hemangiosarcoma / pathology. Humans. Keloid / complications. Keloid / pathology. Lymphoma / pathology. Scalp / pathology

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  • (PMID = 16983449.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Norway
  • [Number-of-references] 56
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31. Padgett JK: Cutaneous lesions: benign and malignant. Facial Plast Surg Clin North Am; 2005 May;13(2):195-202, v
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  • Basal and squamous cell carcinoma, lentigo maligna and lentigo maligna melanoma, dermatofibrosarcoma protuberans, and Merkel cell carcinoma are malignant lesions for which surgical excision is the recommended treatment.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / surgery. Carcinoma, Merkel Cell / diagnosis. Carcinoma, Merkel Cell / surgery. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / surgery. Dermatofibrosarcoma / diagnosis. Dermatofibrosarcoma / surgery. Humans. Hutchinson's Melanotic Freckle / diagnosis. Hutchinson's Melanotic Freckle / surgery. Nevus, Pigmented / diagnosis. Nevus, Pigmented / surgery. Risk Factors. Scalp. Sunlight / adverse effects

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  • (PMID = 15817400.001).
  • [ISSN] 1064-7406
  • [Journal-full-title] Facial plastic surgery clinics of North America
  • [ISO-abbreviation] Facial Plast Surg Clin North Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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32. Neves DR, Ramos DG, Magalhães GM, Rodrigues Rda C, Souza JB: Photodynamic therapy for treatment of multiple lesions on the scalp in nevoid basal cell carcinoma syndrome: case report. An Bras Dermatol; 2010 Jul-Aug;85(4):545-8
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  • [Title] Photodynamic therapy for treatment of multiple lesions on the scalp in nevoid basal cell carcinoma syndrome: case report.
  • Photodynamic therapy is an effective alternative for the treatment of non-melanoma skin cancer, selectively destroying the neoplastic cells through the use of photosensitizer substances that are irradiated with a source of light of adequate wave length.
  • Nevoid Basal Cell Carcinoma Syndrome is a genodermatosis characterized by multiples basal cell carcinomas occurring at an early age, compelling patients to various surgeries, some of them disfiguring.
  • The aim of this article is to show the excellent result of the treatment of multiple basal cell carcinomas on the scalp of a patient suffering from Nevoid Basal Cell Carcinoma Syndrome.
  • [MeSH-major] Basal Cell Nevus Syndrome / drug therapy. Head and Neck Neoplasms / drug therapy. Photochemotherapy / methods. Scalp. Skin Neoplasms / drug therapy


33. Choi CW, Kim BJ, Park ES, Huh CH: Alopecia areata associated with basal cell carcinoma developing within a naevus sebaceus. Br J Dermatol; 2006 Nov;155(5):1090-1
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  • [Title] Alopecia areata associated with basal cell carcinoma developing within a naevus sebaceus.
  • [MeSH-major] Alopecia Areata / etiology. Carcinoma, Basal Cell / complications. Hamartoma / complications. Scalp Dermatoses / complications. Skin Neoplasms / complications
  • [MeSH-minor] Adult. Humans. Male. Scalp


34. Trabelsi A, Stita W, Gharbi O, Kanani N, Sriha B, Korbi S: Malignant proliferating trichilemmal tumor of the scalp: a case report. Dermatol Online J; 2008;14(8):11
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  • [Title] Malignant proliferating trichilemmal tumor of the scalp: a case report.
  • BACKGROUND: Malignant proliferating trichilemmal tumor is a rare skin tumor that affects mainly older women.
  • It mimicks differential squamous cell carcinoma and its biological behavior is unpredictable.
  • OBJECTIVE: To report on a new case of malignant proliferating trichilemmal tumor of the scalp and to describe the clinical and histopathologic findings.
  • METHODS: A tumor measuring 2 cm was surgically excised with a 0.5 cm conservative margin of normal tissue RESULTS: Based on the histopathologic findings of tumor, this case was diagnosed as proliferating trichilemmal tumor of the scalp.
  • After wide excision, long term clinical follow up of the patient for early diagnosis of metastases is judicious.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Neoplasms, Basal Cell / diagnosis. Scalp / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Carcinoma / diagnosis. Cell Division. Diagnosis, Differential. Female. Humans. Keratinocytes / pathology

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  • (PMID = 19061571.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Chiu CS, Lin CY, Kuo TT, Kuan YZ, Chen MJ, Ho HC, Yang LC, Chen CH, Shih IH, Hong HS, Chuang YH: Malignant cutaneous tumors of the scalp: a study of demographic characteristics and histologic distributions of 398 Taiwanese patients. J Am Acad Dermatol; 2007 Mar;56(3):448-52
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  • [Title] Malignant cutaneous tumors of the scalp: a study of demographic characteristics and histologic distributions of 398 Taiwanese patients.
  • BACKGROUND: The scalp is a unique anatomic region, in which pilosebaceous follicles are concentrated.
  • OBJECTIVE: We sought to investigate demographic characteristics and histologic distributions of malignant scalp tumors.
  • METHODS: Primary and metastatic scalp malignancies diagnosed histopathologically between 1983 and 2003 were reviewed.
  • Age at diagnosis, sex, and histologic types were analyzed.
  • Age at diagnosis ranged from 3 to 103 years.
  • Most malignant scalp tumors (69.8%) occurred in those 50 years or older.
  • Basal (41.2%) and squamous (16.6%) cell carcinomas were the most common histologic types.
  • LIMITATIONS: In our series, the case number of metastatic scalp malignancies was underestimated because not all patients with metastatic scalp tumors received a scalp skin biopsy.
  • CONCLUSION: Because a wide spectrum of primary and metastatic malignancies can occur on the scalp, scalp inspection should be included in general screening for either skin or internal cancers.
  • [MeSH-major] Carcinoma, Basal Cell / epidemiology. Carcinoma, Squamous Cell / epidemiology. Head and Neck Neoplasms / epidemiology. Scalp. Skin Neoplasms / epidemiology

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  • (PMID = 17141358.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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36. Litak J, Behroozan D, Binder S: Co-existing basal cell carcinoma and blue nevus in an African-American woman. J Cutan Pathol; 2009 Oct;36(10):1114-6
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  • [Title] Co-existing basal cell carcinoma and blue nevus in an African-American woman.
  • A 67-year-old African-American woman presented with an enlarging darkly pigmented plaque on her scalp.
  • Histopathologic examination revealed a basal cell carcinoma juxtaposed to a blue nevus.
  • Interestingly, the most common types of cutaneous collision tumors include melanocytic nevus and basal cell carcinoma.
  • This is the first documented case of a basal cell carcinoma co-existing alone with a blue nevus.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Neoplasms, Multiple Primary / pathology. Nevus, Blue / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] African Americans. Aged. Female. Humans. Scalp / pathology

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19602062.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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37. Bøgelund FS, Philipsen PA, Gniadecki R: Factors affecting the recurrence rate of basal cell carcinoma. Acta Derm Venereol; 2007;87(4):330-4
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  • [Title] Factors affecting the recurrence rate of basal cell carcinoma.
  • The aim of this retrospective survey was to determine recurrence rates after treatment of basal cell carcinomas in a single academic dermatology department.
  • A total of 1016 patients with 1593 histologically verified basal cell carcinomas (n=1212 primary and n=381 relapsing) were included.
  • The relapse rate for primary basal cell carcinomas on the scalp was highest (odds ratio (OR)=2.8, 95% confidence interval (CI) 1.5-5.3).
  • T2 and T3 tumours showed a 2- and 3-fold increased relapse rate, respectively, compared with T1 basal cell carcinomas.
  • Patients with chronic skin diseases had a 50% lower risk of relapse than healthy patients (OR=0.5, CI=0.3-0.8).
  • Recurrent basal cell carcinomas had a higher relapse rate than primary lesions (OR=1.8, CI=1.4-2.2).
  • Patients treated in a specialized skin cancer unit had a 6.4-fold (CI=2.4-17.4) higher cure rate compared with those treated by less experienced physicians.
  • Treatment in the setting of a specialized skin cancer unit yields a much lower relapse rate.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Neoplasm Recurrence, Local / epidemiology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Clinical Competence. Curettage. Denmark / epidemiology. Dermatology. Face. Female. Hospital Units. Humans. Male. Middle Aged. Photochemotherapy. Retrospective Studies. Scalp

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  • (PMID = 17598036.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
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38. Diver AJ, Rashid A, Gordon DJ: Elastic head dressing for scalp skin grafts. Ann Plast Surg; 2007 Feb;58(2):230-1
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  • [Title] Elastic head dressing for scalp skin grafts.
  • [MeSH-major] Bandages. Scalp / surgery. Skin Transplantation
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / surgery. Elasticity. Female. Humans. Neoplasm Recurrence, Local / surgery. Postoperative Care. Skin Neoplasms / surgery

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  • (PMID = 17245161.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] United States
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39. Tschen EH, Wong DS, Pariser DM, Dunlap FE, Houlihan A, Ferdon MB, Phase IV ALA-PDT Actinic Keratosis Study Group: Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up. Br J Dermatol; 2006 Dec;155(6):1262-9
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  • [Title] Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
  • AKs are believed to progress to in situ squamous cell carcinoma (SCC) and potentially, to invasive SCC.
  • (iii) to characterize the histopathology of untreated clinically diagnosed AK lesions in the study population at baseline; and (iv) to evaluate ALA-PDT in darker skin types than previously studied.
  • METHODS: Patients enrolled in this study had six to 12 discrete AK lesions, either on the face or the scalp.
  • With respect to the lesions biopsied, 91% (127/139) were diagnosed histopathologically as AK, with the balance of lesions being SCC (nine of 139: 7%), basal cell carcinoma (one of 139: 0.7%) and other non-AK diagnoses (two of 139: 1%).
  • The clinical diagnosis of AK by investigators appeared to be accurate, with 91% (200/220) of the untreated clinically diagnosed AK lesions being histopathologically confirmed to be AK (AK, 142/220: 65%; advanced AK, 29/220: 13%; macular AK, 29/220: 13%).
  • Despite concentrated efforts to recruit patients with Fitzpatrick skin types IV-VI, the distribution was as follows: I, 11%; II, 36%; III, 41%; IV, 11%; V, 2%.
  • CONCLUSIONS: ALA-PDT was shown to be an effective and safe therapy for the treatment of AKs of the face and scalp in skin types I-V, with an acceptable rate of recurrence over 12 months of histologically confirmed AKs of 19%.
  • Phototoxicity reactions were all expected, nonserious and had essentially resolved after 1 month post-treatment independent of skin type.
  • [MeSH-major] Aminolevulinic Acid / therapeutic use. Facial Dermatoses / drug therapy. Keratosis / drug therapy. Photochemotherapy. Photosensitizing Agents / therapeutic use. Scalp Dermatoses / drug therapy


40. Harting M, Vujevich J, Goldberg LH: Residual basal cell carcinoma after treatment with imiquimod: a caution on assuming complete cure. Dermatol Surg; 2007 Dec;33(12):1516-9
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  • [Title] Residual basal cell carcinoma after treatment with imiquimod: a caution on assuming complete cure.
  • [MeSH-major] Aminoquinolines / administration & dosage. Antineoplastic Agents / administration & dosage. Carcinoma, Basal Cell / pathology. Neoplasm, Residual / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Administration, Topical. Aged, 80 and over. Female. Humans. Scalp / pathology. Treatment Failure

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  • (PMID = 18076623.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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41. Ulrich C, Johannsen A, Röwert-Huber J, Ulrich M, Sterry W, Stockfleth E: Results of a randomized, placebo-controlled safety and efficacy study of topical diclofenac 3% gel in organ transplant patients with multiple actinic keratoses. Eur J Dermatol; 2010 Jul-Aug;20(4):482-8
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  • Especially, invasive squamous cell carcinomas (SCC) in immuno-compromised patients are characterized by significantly increased morbidity and mortality and characteristically outnumber basal cell carcinoma in this population.
  • Patients who had stable status of the transplanted graft in the 12 months prior to entering the study and >/= 3 AK lesions in a contiguous 50 cm2 area on the face, forehead, hands or balding scalp were eligible for inclusion in the study.
  • Patients were assessed for safety variables that included adverse events, local skin reactions, laboratory results, dosage of immunosuppressive medication and indication of graft rejection.

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  • (PMID = 20507841.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Gels; 0 / Placebos; 144O8QL0L1 / Diclofenac; 9004-61-9 / Hyaluronic Acid
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42. Betti R, Menni S, Radaelli G, Bombonato C, Crosti C: Micronodular basal cell carcinoma: a distinct subtype? Relationship with nodular and infiltrative basal cell carcinomas. J Dermatol; 2010 Jul;37(7):611-6
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  • [Title] Micronodular basal cell carcinoma: a distinct subtype? Relationship with nodular and infiltrative basal cell carcinomas.
  • Micronodular basal cell carcinoma (BCC) may be more difficult to eradicate and prone to recurrence than nodular subtype.
  • The aim of the study was to compare anatomical and histological characteristics of the basal cell carcinomas subtypes and the relationship of the micronodular BCC with other subtypes.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Nose Neoplasms / pathology. Scalp / pathology. Skin Neoplasms / pathology

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  • (PMID = 20629826.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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43. Wei CC, Sanfilippo NJ, Myssiorek D: Re-irradiation of metastatic disease in the neck from xeroderma pigmentosum. Curr Oncol; 2010 Jun;17(3):83-5
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  • Mutation of these enzymes leads to the development of multiple basal cell and squamous cell carcinomas.
  • OBJECTIVES: We present a case of xeroderma pigmentosum in a patient with cervical and intraparotid metastatic disease from recurrent cutaneous squamous cell carcinomas of the face and scalp, treated with neck dissection and re-irradiation.
  • With the illustrative case report, we include a literature review of diagnosis, prognostic factors, and treatment, with emphasis on surgical and radiation treatment of cervical metastatic disease from recurrent skin carcinomas.
  • CASE PRESENTATION: A xeroderma pigmentosum patient presented to our clinic with a 2-cm right submental and 1-cm right infra-auricular mass after resection of multiple squamous cell carcinomas of the scalp and face, and external-beam radiation therapy to the right face and neck.
  • Fine-needle aspiration biopsy of the submental mass revealed poorly differentiated squamous cell carcinoma.
  • Surgical pathology revealed 3 level ia and supraclavicular lymph nodes that were positive for metastatic squamous cell carcinoma.
  • CONCLUSIONS: To our knowledge, this is the first case report in the literature of a patient with xeroderma pigmentosum who subsequently developed metastatic disease from recurrent cutaneous squamous cell carcinoma.

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  • [Cites] J Cutan Med Surg. 1998 Jan;2(3):153-8 [9479081.001]
  • [Cites] Radiother Oncol. 2000 Nov;57(2):143-54 [11054518.001]
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  • (PMID = 20567629.001).
  • [ISSN] 1718-7729
  • [Journal-full-title] Current oncology (Toronto, Ont.)
  • [ISO-abbreviation] Curr Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2880910
  • [Keywords] NOTNLM ; Xeroderma pigmentosum / head-and-neck cancer / radiation / re-irradiation
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44. Chuo CB, Slator R, Brown RM, Anderson KD: Management of desmoplastic trichoepithelioma in an infant. J Plast Reconstr Aesthet Surg; 2008 Oct;61(10):1241-4
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  • [MeSH-major] Carcinoma / pathology. Head and Neck Neoplasms / pathology. Scalp / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Facial Neoplasms / pathology. Female. Humans. Infant. Infant, Newborn. Syringoma / pathology

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  • (PMID = 18554999.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Netherlands
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45. Kovarik CL, Stewart D, Barnard JJ: Lethal basal cell carcinoma secondary to cerebral invasion. J Am Acad Dermatol; 2005 Jan;52(1):149-51
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  • [Title] Lethal basal cell carcinoma secondary to cerebral invasion.
  • Intracranial invasion by a basal cell carcinoma on the scalp is extremely rare.
  • We present an autopsy case of a 57-year-old woman who developed a large destructive basal cell carcinoma with extension through the calvarium and compression of the dura.
  • We compare 7 similar cases reported in the literature and review the risks for development of these aggressive fatal basal cell carcinomas on the scalp.
  • [MeSH-major] Brain Neoplasms / pathology. Carcinoma, Basal Cell / pathology. Scalp. Skin Neoplasms / pathology

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  • (PMID = 15627099.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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46. Nasir S, Kayikcioglu A, Aydin MA, Tunçbilek G: Coverage of the cranium with latissimus dorsi in the recurrent basal cell carcinoma of Gorlin syndrome: for protection against clinical invasion. J Craniofac Surg; 2006 May;17(3):599-602
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  • [Title] Coverage of the cranium with latissimus dorsi in the recurrent basal cell carcinoma of Gorlin syndrome: for protection against clinical invasion.
  • Gorlin's syndrome is a genetic disorder of autosomal dominant inheritance with characterized primarily by five major findings: multiple basal cell carsinoma (BCC), jaw cysts, pits on the palms and soles, ectopic calcification of the falx cerebri and skeletal anomalies.
  • The authors present a 25-year-old man affected by recurrent basal cell carcinoma on the scalp.
  • The fascial component of the scalp forms an additional layer between the skin and the cranium.
  • This structure creates an extra distance before the invasion into the cranium which needs to be penetrated by the skin tumor.
  • Muscle tissue transformed in scalp reconstruction imitates the fascia layer in forming an additional layer against the invasion of skin tumors such as recurrent BCC into the cranium.
  • Free flap reconstruction for recurrent scalp BCC can be best therapy model at Gorlin's syndrome.
  • [MeSH-major] Basal Cell Nevus Syndrome / surgery. Carcinoma, Basal Cell / surgery. Muscle, Skeletal / transplantation. Scalp / surgery. Skin Neoplasms / surgery. Skull / surgery
  • [MeSH-minor] Adult. Clinical Protocols. Fascia / transplantation. Follow-Up Studies. Humans. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / surgery. Skin Transplantation / methods

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  • (PMID = 16770207.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Lin MH, Lee JY, Ou CY, Wong TW: Sequential systemic retinoid and photodynamic therapy for multiple keratotic pigmented nodular basal cell carcinomas on the scalp. J Dermatol; 2009 Sep;36(9):518-21
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  • [Title] Sequential systemic retinoid and photodynamic therapy for multiple keratotic pigmented nodular basal cell carcinomas on the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / drug therapy. Etretinate / therapeutic use. Neoplasms, Multiple Primary / drug therapy. Photochemotherapy. Scalp. Skin Neoplasms / drug therapy

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  • [CommentOn] Br J Dermatol. 2003 Jul;149(1):205-6 [12890225.001]
  • (PMID = 19712282.001).
  • [ISSN] 1346-8138
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Keratolytic Agents; 65M2UDR9AG / Etretinate
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48. Karsidag S, Ozcan A, Ozkaya O, Ugurlu K, Bas L: Use of wide bipedicled pericranial flap in anterior scalp reconstruction. J Craniofac Surg; 2009 Nov;20(6):2248-51
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  • [Title] Use of wide bipedicled pericranial flap in anterior scalp reconstruction.
  • In our study, we have performed wide bipedicled pericranial flap in scalp reconstruction in 2 cases.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Skin Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Ear, External / blood supply. Fascia / transplantation. Humans. Male. Middle Aged. Periosteum / transplantation. Skin Transplantation


49. Maillard GF, Garey L: Plastic surgery after ablative cancer surgery. Aesthetic Plast Surg; 2006 Jan-Feb;30(1):47-52
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  • [Title] Plastic surgery after ablative cancer surgery.
  • A number of personal cases are used to illustrate that reconstruction after cancer surgery, even reconstruction of some large tumors, can be performed with modern modifications of classic local flaps, but that sound knowledge and skill in basic surgical and plastic techniques are inescapable prerequisites.
  • [MeSH-minor] Breast Neoplasms / pathology. Breast Neoplasms / surgery. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Humans. Lip Neoplasms / pathology. Lip Neoplasms / surgery. Nose Neoplasms / pathology. Nose Neoplasms / surgery. Parotid Neoplasms / pathology. Parotid Neoplasms / surgery. Scalp. Skin Neoplasms / pathology. Skin Neoplasms / surgery. Surgical Flaps

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  • (PMID = 16402163.001).
  • [ISSN] 0364-216X
  • [Journal-full-title] Aesthetic plastic surgery
  • [ISO-abbreviation] Aesthetic Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Vujevich JJ, Goldberg LH, Kimyai-Asadi A: Mohs micrographic surgery using a flexible blade for tumors of the scalp. Dermatol Surg; 2009 Jul;35(7):1130-3
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  • [Title] Mohs micrographic surgery using a flexible blade for tumors of the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Mohs Surgery. Scalp / surgery. Skin Neoplasms / surgery

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  • (PMID = 19438683.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Wu Y, Chai J, Liu C: [Repair of immedicable ulcer in skull cap with expanded bipedical axial flap in senile patients]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2007 Sep;21(9):917-20
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  • Among them, the causes of disease were trauma in 1 case, infection in 1 case, squamous cell carcinoma in 2 cases, and basal cell carcinoma in 1 case.
  • And the donor site was covered with odd expanded flap or split-thickness skin graft.
  • [MeSH-major] Forehead / surgery. Scalp / injuries. Surgical Flaps / blood supply. Tissue Expansion. Ulcer / surgery
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / surgery. Graft Survival. Humans. Male. Middle Aged. Reoperation. Wound Healing / physiology

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  • (PMID = 17933221.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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52. Lindemalm-Lundstam B, Dalenbäck J: Prospective follow-up after curettage-cryosurgery for scalp and face skin cancers. Br J Dermatol; 2009 Sep;161(3):568-76
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  • [Title] Prospective follow-up after curettage-cryosurgery for scalp and face skin cancers.
  • BACKGROUND: Cryosurgery (CS) in the treatment of nonmelanoma skin cancers (NMSCs), especially in the face and on the scalp, has several advantages vs. other methods.
  • OBJECTIVES: To establish long-term results after curettage and CS (CCS) of NMSCs in the face and on the scalp considering complication rate, patient tolerance, cosmetic outcome and rate of recurrence.
  • METHODS: Seven hundred and twenty-six patients with 962 face and scalp NMSCs were prospectively followed after CCS (1 week, 3 months, and then annually) during the time period December 1994-September 2008.
  • CCS is thus a highly viable alternative in the treatment of NMSCs in the face and on the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Cryosurgery / methods. Head and Neck Neoplasms / surgery. Scalp. Skin Neoplasms / surgery

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  • (PMID = 19624544.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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53. Qing Y, Cen Y, Wang H, Liu Y: [Surgical treatment of scalp malignant tumor]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2008 Jan;22(1):59-62
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  • [Title] [Surgical treatment of scalp malignant tumor].
  • OBJECTIVE: To investigate the effects of different surgical methods in treating scalp malignant tumors.
  • METHODS: From January 1995 to September 2004, 70 patients with scalp malignant tumor were treated with different surgical methods.
  • There were 31 cases of basal cell carcinoma, 24 cases of squamous carcinoma, 8 cases of melanocarcinoma, 4 cases of fibrous sarcoma, 2 cases of liposarcoma, and 1 case of vasculosarcoma.
  • Scalp defect ranged from 3 cm x 3 cm to 12 cm x 11 cm after clearing up the tumors.
  • Defect was repaired withfree skin transplantation in 51 cases, scalp flap in 12 cases, cervico-shoulder flap in 2 cases, trapizius myocutaneous flap in 3 cases, and radial artery retro-island flap in 2 cases.
  • RESULTS: Of 70 cases, 67 skin flaps survived and incision healed by first intention; 2 flaps necrosed at distal part (< 1 cm) and healed by second intention after dressing change; 1 flap infected and was treated with symptomatic medication.
  • In patients receiving skin transplantation, 1 case of squamous carcinoma and 1 case of fibrous sarcoma relapsed after 1 year and 2.5 years respectively and were given radical resection and skin flap grafting; in patients receiving skin flap grafting, 1 case of vasculosarcoma and 1 case of squamous carcinoma relapsed after 6 months and 3 months respectively, and gave up treatment; 1 case of fibrous sarcoma relapsed after 2 years and was given radical resection and skin flap grafting.
  • CONCLUSION: Scalp malignant tumors should be diagnosised and treated as early as possible.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Scalp. Skin Neoplasms / surgery. Skin Transplantation / methods. Surgical Flaps

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  • (PMID = 18361240.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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54. Metz BJ, Katta R: Burow's advancement flap closure of adjacent defects. Dermatol Online J; 2005;11(1):11
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  • [MeSH-major] Head and Neck Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Scalp / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / surgery. Humans. Male. Skin Neoplasms / surgery

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  • (PMID = 15748552.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Abedalthagafi M, Rushing EJ, Auerbach A, Desouki MM, Marwaha J, Wang Z, Fanburg-Smith JC: Sporadic cutaneous angiosarcomas generally lack hypoxia-inducible factor 1alpha: a histologic and immunohistochemical study of 45 cases. Ann Diagn Pathol; 2010 Feb;14(1):15-22
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  • Tumors presented most commonly in the skin of the scalp followed by the left lower leg, face, nose, lower arm, neck, thigh, eyelid, ear, and temple.
  • Associated basal cell carcinoma was noted in 1 patient; no others had other neoplasms or unrelated surgeries.
  • Cutaneous angiosarcoma is largely found on the scalp of older individuals.
  • Requirement for diagnosis includes extravascular proliferation of atypical endothelial cells with mitotic activity in vasoformative, solid, and papillary patterns.
  • [MeSH-major] Dermis / metabolism. Hemangiosarcoma / metabolism. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Neovascularization, Pathologic / metabolism. Skin Neoplasms / metabolism

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  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20123452.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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56. Cohen PR, Schulze KE, Nelson BR: Basal cell carcinoma with mixed histology: a possible pathogenesis for recurrent skin cancer. Dermatol Surg; 2006 Apr;32(4):542-51
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  • [Title] Basal cell carcinoma with mixed histology: a possible pathogenesis for recurrent skin cancer.
  • BACKGROUND: Basal cell carcinoma with mixed histology (BCC-MH) demonstrates more than one pathologic pattern of tumor.
  • Appropriate therapy for the nonaggressive tumor subtype diagnosed from a superficial biopsy may not be adequate to treat the unsuspected aggressive tumor subtype, resulting in recurrent skin cancer.
  • CONCLUSION: More than 40% of basal cell carcinomas referred for removal of the residual tumor were BCC-MH.
  • Subsequently, the cancer may recur if the initial treatment for the diagnosed nonaggressive tumor subtype is inadequate for the undiscovered aggressive carcinoma.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Facial Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cheek / pathology. Ear Neoplasms / pathology. Ear Neoplasms / surgery. Female. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery. Humans. Male. Middle Aged. Mohs Surgery. Nose Neoplasms / pathology. Nose Neoplasms / surgery. Prospective Studies. Scalp / pathology

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  • (PMID = 16681663.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 66
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57. Krahl D, Sellheyer K: Basal cell carcinoma and pilomatrixoma mirror human follicular embryogenesis as reflected by their differential expression patterns of SOX9 and β-catenin. Br J Dermatol; 2010 Jun;162(6):1294-301
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  • [Title] Basal cell carcinoma and pilomatrixoma mirror human follicular embryogenesis as reflected by their differential expression patterns of SOX9 and β-catenin.
  • BACKGROUND: The current classification schemes of adnexal tumours are predominantly based on morphological and immunophenotypical similarities to adult skin structures, whereas a link between the embryology of the skin and the histogenesis of adnexal tumours has been largely neglected.
  • OBJECTIVE: To describe the expression patterns of two proteins with proven relevance for hair follicle homeostasis (SOX9 and β-catenin) during human cutaneous embryogenesis and to compare the findings with their expression in basal cell carcinoma (BCC) and pilomatrixoma.
  • METHODS: Immunohistochemical evaluation with monoclonal antibodies against SOX9 and β-catenin was carried out in embryonic and adult human scalp skin, and BCC and pilomatrixoma samples.
  • [MeSH-major] Carcinoma, Basal Cell / metabolism. Hair Diseases / metabolism. Hair Follicle / metabolism. Pilomatrixoma / metabolism. SOX9 Transcription Factor / metabolism. Skin Neoplasms / metabolism. beta Catenin / metabolism
  • [MeSH-minor] Adult. Humans. Neoplasm Proteins / metabolism. Skin / embryology. Skin / metabolism

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  • [Copyright] © 2010 The Authors. Journal Compilation © 2010 British Association of Dermatologists.
  • (PMID = 20105172.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / SOX9 Transcription Factor; 0 / SOX9 protein, human; 0 / beta Catenin
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58. Jahan-Tigh RR, Alston JL, Umphlett M: Basal cell carcinoma with metastasis to the lung in an African American man. J Am Acad Dermatol; 2010 Oct;63(4):e87-9
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  • [Title] Basal cell carcinoma with metastasis to the lung in an African American man.
  • [MeSH-major] Carcinoma, Basal Cell / secondary. Lung Neoplasms / radiotherapy. Lung Neoplasms / secondary. Palliative Care. Scalp / pathology. Skin Neoplasms / pathology

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  • (PMID = 20846562.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] United States
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59. Katz TM, Silapunt S, Goldberg LH, Jih MH, Kimyai-Asadi A: Analysis of 197 female scalp tumors treated with Mohs micrographic surgery. J Am Acad Dermatol; 2005 Feb;52(2):291-4
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  • [Title] Analysis of 197 female scalp tumors treated with Mohs micrographic surgery.
  • BACKGROUND: There has been no previously published study on skin cancers on the scalp of women.
  • OBJECTIVES: To better elucidate the characteristics of skin cancers that develop on the female scalp.
  • METHODS: A retrospective review of 13,885 biopsy-proven skin cancers treated by Mohs micrographic surgery was performed.
  • We identified 197 tumors on the scalp of women.
  • RESULTS: The average age of women with scalp tumors was 61.8 +/- 16.9, which was significantly lower than that of men with scalp tumors.
  • Overall, 77% of female scalp tumors were basal cell carcinomas (BCCs), 17% were squamous cell carcinomas (SCCs), and 6% were a variety of other tumors.
  • This contrasts with men in whom 53% of tumors were squamous cell carcinomas.
  • Basal cell carcinomas were significantly more common in women under age 50.
  • CONCLUSION: Skin cancers of the female scalp tend to be basal cell carcinomas, many of which occur at a relatively young age as compared to other skin cancers.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / surgery. Mohs Surgery. Scalp / surgery. Skin Neoplasms / surgery

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  • (PMID = 15692476.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 7
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60. Premalata CS, Kumar RV, Malathi M, Shenoy AM, Nanjundappa N: Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus. Int J Dermatol; 2007 Mar;46(3):306-8
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  • A 54-year-old man presented with a recurrent swelling on the right occipital region of the scalp.
  • The specimen of the initial surgery consisted of skin-covered tissue with an exophytic firm growth measuring 6 x 5 x 4 cm.
  • The skin surface was rough with areas of ulceration.
  • One was a well-circumscribed tumor located in the superficial dermis with lobules of basaloid cell aggregates with peripheral palisading and with no epidermal connection.
  • Unlike basal cell carcinoma, however, no cleft between the cellular aggregates and stroma was noted.
  • Foci of pigmentation were seen within cellular lobules and these features were consistent with a diagnosis of tricho-blastoma.
  • The third lesion was a spindle cell sarcoma which formed the major part of the lesion, diffusely infiltrating the dermis and subcutaneous tissue, elevating and ulcerating the overlying skin.
  • The wide excision specimen of the recurrent swelling consisted of a skin-covered nodule with ulceration, measuring 3 x 4 x 3 cm, with a gray-white whorled cut surface.
  • Multiple sections showed only spindle cell sarcoma infiltrating the skin and subcutaneous tissue, morphologically similar to the earlier tumor, with ulceration of the overlying skin.
  • Immunohistochemical stains on the spindle cell sarcoma showed positive staining for smooth muscle actin (SMA) (Fig.
  • Correlating the histomorphology and immunohistochemical findings, a diagnosis of cutaneous leiomyosarcoma with tricho-blastoma and syringocystadenoma papilliferum arising on nevus sebaceus was made.
  • The patient received postoperative radiotherapy and is disease free 8 months after diagnosis.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Nevus / pathology. Scalp. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


61. Walsh SN, Hurt MA, Santa Cruz DJ: Psoriasiform keratosis. Am J Dermatopathol; 2007 Apr;29(2):137-40
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  • There was, however, no known clinical diagnosis of psoriasis in any patient, neither at initial presentation nor on follow-up examination.
  • Other sites included the scalp, neck, shoulders, and back.
  • The mean age at diagnosis was 66.8 years.
  • The most common diagnoses, clinically, were seborrheic keratosis, followed by basal cell carcinoma, Bowen's disease, actinic (solar) keratosis, and squamous cell carcinoma, among others.
  • [MeSH-major] Keratosis, Seborrheic / pathology. Psoriasis / pathology. Skin / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Lichenoid Eruptions / pathology. Lymphocytes / pathology. Male. Middle Aged. Neutrophils / pathology. Prospective Studies. Terminology as Topic. Time Factors

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  • (PMID = 17414434.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Wain RA, Shah SH, Senarath-Yapa K, Laitung JK: Dermal substitutes do well on dura: comparison of split skin grafting+/-artificial dermis for reconstruction of full-thickness calvarial defects. J Plast Reconstr Aesthet Surg; 2010 Dec;63(12):e826-8
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  • [Title] Dermal substitutes do well on dura: comparison of split skin grafting+/-artificial dermis for reconstruction of full-thickness calvarial defects.
  • We believe that artificial dermis coupled with split-thickness skin grafting provides an excellent option for closure of these defects when other techniques are not appropriate.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Chondroitin Sulfates / therapeutic use. Collagen / therapeutic use. Head and Neck Neoplasms / surgery. Scalp. Skin Neoplasms / surgery. Skin Transplantation. Skin, Artificial. Skull / surgery

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  • [Copyright] Copyright © 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • [ReprintIn] Clin Plast Surg. 2012 Jan;39(1):65-7 [22099849.001]
  • (PMID = 20709614.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / integra artificial skin; 9007-28-7 / Chondroitin Sulfates; 9007-34-5 / Collagen
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63. Hauser J, Homann HH, Drücke D, Kuhnen C, Esenwein SA, Steinau HU: [Desmoplastic neurotropic melanoma. Diagnosis and therapeutic procedures for a rare clinical entity]. Chirurg; 2006 Oct;77(10):939-42
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  • [Title] [Desmoplastic neurotropic melanoma. Diagnosis and therapeutic procedures for a rare clinical entity].
  • In this paper, a 79-year-old patient with a basal cell carcinoma and desmoplastic melanoma on the scalp is described, and the therapeutic procedure is discussed.
  • [MeSH-major] Melanoma / surgery. Neoplasms, Multiple Primary / surgery. Scalp / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / diagnosis. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Diagnosis, Differential. Female. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Surgical Flaps

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  • [Cites] Cancer. 1971 Oct;28(4):914-36 [5286448.001]
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  • (PMID = 16425057.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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64. Chaichamnan K, Satayasoontorn K, Puttanupaab S, Attainsee A: Malignant proliferating trichilemmal tumors with CD34 expression. J Med Assoc Thai; 2010 Nov;93 Suppl 6:S28-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Malignant proliferating trichilemmal tumors (MPTT) are rare neoplasm arising from outer root sheath of hair follicle, the diagnosis of which is base essentially on histological features resulting in occasionally misdiagnosis of squamous cell carcinoma.
  • In difficult cases, however evaluation of additional parameters may be needed to differentiate benign proliferating trichilemmal tumor from MPTT or differentiate PTT and MPTT from squamous cell carcinoma.
  • For comparison, concurrent proliferating trichilemmal tumors (PTT) and trichilemmal cysts (TC) as well as well-differentiated squamous cell carcinoma (SCC) were studied.
  • The PTTs and TCs stained negative and few basal cells for p53 and Ki-67, respectively.
  • The contrast p53 and Ki-67 expression pattern in MPTT and PTT may be helpful in the diagnosis of MPTT.
  • [MeSH-major] Antigens, CD34 / metabolism. Carcinoma, Squamous Cell / metabolism. Epidermal Cyst / pathology. Hair Follicle / pathology. Scalp / pathology. Skin Neoplasms / pathology. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Recurrence, Local. Treatment Outcome

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  • (PMID = 21280514.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Tumor Suppressor Protein p53
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65. Birgfeld CB, Chang B: The periglabellar flap for closure of central forehead defects. Plast Reconstr Surg; 2007 Jul;120(1):130-3
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  • Constraints include tissue match, hair-bearing scalp, proximity of eyelids and eyebrows, and a cosmetically prominent location.
  • This article describes a local flap for reconstructing central forehead skin defects that achieves tissue coverage with a cosmetically appealing result.
  • The defects were closed using bilateral periglabellar local advancement flaps with Burow's triangles, with scars in the natural skin creases of the aging forehead.
  • The inferior triangles were oriented obliquely within skin creases of the corrugator muscles.
  • RESULTS: Five patients with central forehead melanomas and one patient with Mohs' defects after excision of basal cell carcinoma were referred by their dermatologists (age range, 60 to 83 years; mean, 72 years).
  • CONCLUSION: For central forehead skin defects up to 5 cm in diameter, the periglabellar flap offers a reconstructive option that uses local tissue and hides scars within natural forehead wrinkles, providing an aesthetically pleasing result.
  • [MeSH-major] Facial Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Cohort Studies. Esthetics. Forehead. Graft Rejection. Graft Survival. Humans. Melanoma / pathology. Melanoma / surgery. Middle Aged. Mohs Surgery / adverse effects. Mohs Surgery / methods. Retrospective Studies. Risk Assessment. Treatment Outcome. Wound Healing / physiology

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  • (PMID = 17572554.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Nassab RS, Thomas SS, Murray D: Orbital exenteration for advanced periorbital skin cancers: 20 years experience. J Plast Reconstr Aesthet Surg; 2007;60(10):1103-9
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  • [Title] Orbital exenteration for advanced periorbital skin cancers: 20 years experience.
  • The majority of these were for basal cell carcinomas (53%).
  • Reconstructive techniques included split skin grafting (63%), forehead (25%), scalp (6%) and cervicofacial (6%) flaps.
  • CONCLUSIONS: Though there are various options available for reconstruction after orbital exenteration, a split skin graft and orbital prosthesis provide a simple solution for a very difficult problem of advanced periorbital skin cancer in the elderly population with significant comorbidities.
  • [MeSH-major] Facial Neoplasms / surgery. Orbit Evisceration. Orbital Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Melanoma / surgery. Middle Aged. Orbital Implants. Retrospective Studies. Sebaceous Gland Neoplasms / surgery. Skin Transplantation / methods. Surgical Flaps. Treatment Outcome

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  • (PMID = 17434350.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 43
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67. Stojicic MT, Slavik EE, Acimovic GT, Jovanovic MD, Stojmirovic DM, Vujotic LD: Simultaneous surgical treatment of ulcer terebrans with intracranial propagation and acoustic neurinoma on the same side: a case report. J Plast Reconstr Aesthet Surg; 2008 Nov;61(11):e9-11
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  • This article presents a successful surgical treatment of the patient with aggressive basal cell carcinoma with intracranial propagation (ulcer terebrans) and simultaneous acoustic neurinoma on the same side.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Neoplasms, Multiple Primary / surgery. Neuroma, Acoustic / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Brain / pathology. Female. Humans. Magnetic Resonance Imaging. Meninges / pathology. Middle Aged. Neoplasm Invasiveness. Reconstructive Surgical Procedures / methods. Scalp / pathology

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  • (PMID = 18718834.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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68. Masui Y, Komine M, Kadono T, Ishiura N, Maekawa T, Ihn H, Kikuchi K, Tamaki K: Proliferating tricholemmal cystic carcinoma: a case containing differentiated and dedifferentiated parts. J Cutan Pathol; 2008 Oct;35 Suppl 1:55-8
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  • [Title] Proliferating tricholemmal cystic carcinoma: a case containing differentiated and dedifferentiated parts.
  • A 46-year-old man had a cystic mass on the right side of his scalp.
  • Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricholemmal cystic carcinoma (PTCC).
  • The dedifferentiated and mildly differentiated parts exhibited a high frequency of proliferating cell nuclear antigen (PCNA)-positive cells both in the basal and the suprabasal layers, while PCNA staining was almost negative in the TC-like part.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Cysts / pathology. Scalp / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Cell Differentiation. Humans. Immunohistochemistry. Keratin-10 / metabolism. Keratin-16 / metabolism. Male. Middle Aged. Proliferating Cell Nuclear Antigen / metabolism

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  • [Copyright] Copyright Blackwell Munksgaard 2008.
  • (PMID = 18544060.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Keratin-16; 0 / Proliferating Cell Nuclear Antigen; 147785-83-9 / Keratin-10
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69. Misago N, Sada A, Narisawa Y: Trichoblastoma with a dilated pore. J Am Acad Dermatol; 2006 Feb;54(2):357-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Scalp. Skin Neoplasms / pathology

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  • (PMID = 16443076.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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70. Asilian A, Tamizifar B: Aggressive and neglected basal cell carcinoma. Dermatol Surg; 2005 Nov;31(11 Pt 1):1468-71
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  • [Title] Aggressive and neglected basal cell carcinoma.
  • BACKGROUND: Basal cell carcinoma (BCC) is the most common cutaneous malignancy and usually has a benign coarse.
  • RESULTS: The patient had a large, infected ulcer on his scalp.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery
  • [MeSH-minor] Cranial Nerve Diseases / pathology. Cranial Nerve Diseases / radiography. Cranial Nerves / pathology. Humans. Male. Middle Aged. Scalp / pathology. Tomography, X-Ray Computed

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  • (PMID = 16416624.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Mseddi M, Dammak A, Jellouli M, Ghorbel S, Bouassida S, Marrekchi S, Zahaf A, Turki H: [Profile of basal cell carcinomas of the scalp after radiotherapy for tinea capitis (about 63 cases)]. Rev Med Liege; 2006 Oct;61(10):724-7
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  • [Title] [Profile of basal cell carcinomas of the scalp after radiotherapy for tinea capitis (about 63 cases)].
  • [Transliterated title] Profil des carcinomes basocellulaires du cuir chevelu secondaires a une radiothérapie pour teigne (a propos de 63 cas).
  • The induction of basal cell carcinoma (BCC) of the scalp by X-ray therapy for tinea capitis is well known.
  • Fifty one men and 12 women with a total of 108 BCC of the scalp are reported (1.76 lesion per patient and 1.13 cm on average of diameter).
  • It is concluded that BCC of the scalp following X-ray therapy for tinea capitis have some clinical and histological particularities.
  • It represents the most frequent tumour developing on irradiated scalp.
  • [MeSH-major] Carcinoma, Basal Cell / etiology. Head and Neck Neoplasms / etiology. Neoplasms, Radiation-Induced / etiology. Scalp. Skin Neoplasms / etiology. Tinea Capitis / radiotherapy

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  • (PMID = 17209506.001).
  • [ISSN] 0370-629X
  • [Journal-full-title] Revue médicale de Liège
  • [ISO-abbreviation] Rev Med Liege
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Belgium
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72. Lo CH, Thomson SJ: Nodular cystic metastatic basal cell carcinoma: a rare occurrence. ANZ J Surg; 2007 Jun;77(6):493-4
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  • [Title] Nodular cystic metastatic basal cell carcinoma: a rare occurrence.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Head and Neck Neoplasms / pathology. Scalp. Skin Neoplasms / pathology

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  • [CommentIn] ANZ J Surg. 2007 Dec;77(12):1129 [17973679.001]
  • (PMID = 17501899.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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73. Barcelos AC, Nico MM: Bazex-Dupré-Christol syndrome in a 1-year-old boy and his mother. Pediatr Dermatol; 2008 Jan-Feb;25(1):112-3
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  • Bazex-Dupré-Christol syndrome is a rare genodermatosis with cancer predisposition, characterized by follicular atrophoderma, multiple milia, congenital hypotrichosis, hypohidrosis and basal cell malformations that include nevoid basal cell carcinomas of early onset.
  • We present two patients with this syndrome, a 1-year-old boy with diffuse scalp and eyebrows alopecia, milia papules on the face, ears, trunk, and limbs.
  • She also had a basal cell carcinoma on her face.
  • [MeSH-major] Basal Cell Nevus Syndrome / genetics. Carcinoma, Basal Cell / pathology. Heterozygote. Precancerous Conditions / pathology. Skin Neoplasms / genetics
  • [MeSH-minor] Acrodermatitis / diagnosis. Acrodermatitis / genetics. Adolescent. Cell Transformation, Neoplastic. Female. Humans. Hypohidrosis / diagnosis. Hypohidrosis / genetics. Hypotrichosis / diagnosis. Hypotrichosis / genetics. Infant. Male. Mothers. Pedigree. Prognosis. Syndrome

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  • (PMID = 18304168.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Kazakov DV, Mentzel T, Erlandson RA, Mukensnabl P, Michal M: Clear cell trichoblastoma: a clinicopathological and ultrastructural study of two cases. Am J Dermatopathol; 2006 Jun;28(3):197-201
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  • [Title] Clear cell trichoblastoma: a clinicopathological and ultrastructural study of two cases.
  • Clear cell change in basal cell carcinomas is a well-recognized phenomenon, but is obviously rare in trichoblastomas.
  • We present two cases of clear cell trichoblastoma in which clear cell change was very much prominent, and the results of an ultrastructural study intended to explore the basis of that feature.
  • Both our patients were women, aged 56 and 77 years, who presented with solitary, slowly growing nodules that measured 3 to 5 cm in largest dimension and were located on the scalp and the flexor aspect of the lower arm.
  • Common to both tumors was clear cell cytoplasm evident in the majority of the epithelial cells in one case and almost in the entire epithelial cell population in the other.
  • In most epithelial aggregations the epithelial cells with clear cytoplasm often appeared columnar and were arranged in a palisade along a recognizable basal membrane, thus indicative of outer sheath differentiation at the bulb.
  • In addition to the usual organelles, the cytoplasm contained fairly conspicuous tonofilaments and variably sized vacuoles devoid of a limiting membrane, located between the palisaded nuclei and the outer cell membrane.
  • [MeSH-major] Carcinoma, Basal Cell / ultrastructure. Head and Neck Neoplasms / ultrastructure. Neoplasms, Adnexal and Skin Appendage / ultrastructure. Skin Neoplasms / ultrastructure
  • [MeSH-minor] Aged. Basement Membrane / ultrastructure. Cell Nucleus / ultrastructure. Cytoplasm / ultrastructure. Desmosomes / ultrastructure. Epithelial Cells / ultrastructure. Female. Humans. Middle Aged

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  • (PMID = 16778484.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Rosen H, Schmidt B, Lam HP, Meara JG, Labow BI: Management of nevus sebaceous and the risk of Basal cell carcinoma: an 18-year review. Pediatr Dermatol; 2009 Nov-Dec;26(6):676-81
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  • [Title] Management of nevus sebaceous and the risk of Basal cell carcinoma: an 18-year review.
  • Nevus sebaceous (NS) is a common congenital hamartoma of the skin, usually found on the head and neck.
  • It may undergo malignant transformation to basal cell carcinoma (BCC).
  • [MeSH-major] Carcinoma, Basal Cell / epidemiology. Nevus / epidemiology. Nevus / surgery. Sebaceous Gland Neoplasms / epidemiology. Sebaceous Gland Neoplasms / surgery. Skin Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Cystadenocarcinoma, Papillary / epidemiology. Cystadenocarcinoma, Papillary / pathology. Cystadenocarcinoma, Papillary / surgery. Databases, Factual. Facial Neoplasms / epidemiology. Facial Neoplasms / pathology. Facial Neoplasms / surgery. Female. Follow-Up Studies. Hamartoma / epidemiology. Hamartoma / pathology. Hamartoma / surgery. Humans. Incidence. Infant. Male. Medical Records. Middle Aged. Retrospective Studies. Risk Factors. Scalp / pathology. Young Adult


76. Pragnell J, Neilson J: The social and psychological impact of hard-to-heal wounds. Br J Nurs; 2010 Oct 28-Nov 10;19(19):1248-52
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  • This article examines the experience of a woman treated for basal cell carcinoma of the scalp--both the immediate emotional impact of the individual stages of treatment and the wider impact on her lifestyle and her family.
  • [MeSH-major] Attitude to Health. Carcinoma, Basal Cell / psychology. Cost of Illness. Scalp. Skin Neoplasms / psychology. Wound Healing
  • [MeSH-minor] Amelogenin / economics. Amelogenin / therapeutic use. Exudates and Transudates. Female. Humans. Life Style. Middle Aged. Mohs Surgery. Pain / etiology. Quality of Life / psychology. Skin Care / methods. Skin Care / nursing. Skin Care / psychology. Surgical Flaps

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  • (PMID = 21155363.001).
  • [ISSN] 0966-0461
  • [Journal-full-title] British journal of nursing (Mark Allen Publishing)
  • [ISO-abbreviation] Br J Nurs
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Amelogenin
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77. Yazici AC, Unal S, Ikizoglu G, Kokturk A, Baz K, Cinel L, Koca A: Superficial basal cell carcinoma of the scalp mimicking seborrhoeic dermatitis. Scand J Plast Reconstr Surg Hand Surg; 2006;40(1):54-6
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  • [Title] Superficial basal cell carcinoma of the scalp mimicking seborrhoeic dermatitis.
  • Superficial basal cell carcinomas (BCC) comprise 9% to 11% of BCC, and are commonly found on the trunk or limbs.
  • We report a case of a superficial BCC on the scalp that was misdiagnosed and treated as seborrhoeic dermatitis.
  • Any erythematous plaque-type lesion of long duration must have superficial BCC considered in the differential diagnosis.

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  • (PMID = 16428215.001).
  • [ISSN] 0284-4311
  • [Journal-full-title] Scandinavian journal of plastic and reconstructive surgery and hand surgery
  • [ISO-abbreviation] Scand J Plast Reconstr Surg Hand Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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78. Katona TM, Billings SD, Montironi R, Lopez-Beltran A, Cheng L: Expression of OCT4 transcription factor in cutaneous neoplasia. Appl Immunohistochem Mol Morphol; 2007 Dec;15(4):359-62
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  • The OCT4 transcription factor is a marker of pluripotency and is present in embryonic stem cells, primordial germ cells, and several neoplasms including seminoma, dysgerminoma, and embryonal carcinoma.
  • Recently, immunohistochemical expression of OCT4 protein has been described in the cells within the basal layer of normal human and canine epidermis.
  • We have examined a series of basal cell carcinomas and adnexal tumors of related histogenesis, in an effort to corroborate the above findings and to assess for expression of OCT4 protein in neoplasia of the infundibulo-apocrine-sebaceous unit.
  • We analyzed OCT4 expression in 115 cutaneous specimens including 26 basal cell carcinomas, 12 benign follicular tumors (10 trichoepitheliomas and 2 trichoblastomas), 10 benign apocrine tumors, 12 sebaceous hyperplasia lesions, 10 sebaceous adenomas, 4 sebaceous carcinomas, 13 nevi sebacei of Jadassohn, 8 squamous cell carcinomas (including one spindle-cell squamous cell carcinoma), 8 compound melanocytic nevi, 5 Merkel cell carcinomas, 3 pilar cysts, 1 scar, 2 nonspecific, mild superficial perivascular dermatitis specimens, and 1 non-scarring alopecia.
  • In contrast to previous studies, our data indicate that the OCT4 expression is not retained in cutaneous neoplasms derived from basal epidermis or related adnexal neoplasms, including lesions of the scalp.

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  • (PMID = 18091376.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Octamer Transcription Factor-3; 0 / POU5F1 protein, human
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79. Buggiani G, Troiano M, Rossi R, Lotti T: Photodynamic therapy: off-label and alternative use in dermatological practice. Photodiagnosis Photodyn Ther; 2008 Jun;5(2):134-8
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  • Photodynamic therapy (PDT) is a treatment technique that permits the clearance of different skin lesions with high success rates in many dermatological diseases.
  • Worldwide recognized uses for PDT in dermatology include non-melanoma skin cancer, actinic keratoses, acne vulgaris, photorejuvenation, and hidradenitis suppurativa.
  • In the European Union, and in the USA, its indication is for the treatment of nonhyperkeratotic actinic keratoses (AKs) of the face and scalp, for basal cell carcinoma and for Bowen's disease.
  • [MeSH-major] Dermatology. Photochemotherapy. Skin Diseases / therapy

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  • (PMID = 19356644.001).
  • [ISSN] 1873-1597
  • [Journal-full-title] Photodiagnosis and photodynamic therapy
  • [ISO-abbreviation] Photodiagnosis Photodyn Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 44
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80. Balle JR, Hasselager T: [Kaposi's sarcoma interpreted as haematoma]. Ugeskr Laeger; 2010 Aug 30;172(35):2388-9
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  • Kaposi's sarcoma is a frequent skin cancer in HIV-positive patients, but is relatively uncommon in HIV-negative and non-immune compromised patients.
  • We present a case of Kaposi's sarcoma of the face and scalp in a HIV-negative male with previous facial basal cell carcinoma.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Sarcoma, Kaposi / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Facial Neoplasms / diagnosis. Facial Neoplasms / pathology. Humans. Male. Scalp / pathology

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  • (PMID = 20825744.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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81. Vila J, Langtry JA: Delayed bleeding from the superficial temporal artery after local flap reconstruction. Dermatol Surg; 2009 Jan;35(1):155-7
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  • [MeSH-minor] Carcinoma, Basal Cell / surgery. Humans. Male. Middle Aged. Scalp Dermatoses / surgery. Skin Neoplasms / surgery

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  • (PMID = 19076185.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Griffiths RW, Suvarna SK, Stone J: Basal cell carcinoma histological clearance margins: an analysis of 1539 conventionally excised tumours. Wider still and deeper? J Plast Reconstr Aesthet Surg; 2007;60(1):41-7
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  • [Title] Basal cell carcinoma histological clearance margins: an analysis of 1539 conventionally excised tumours. Wider still and deeper?
  • An analysis of peripheral and deep margins of histological clearance around 1539 consecutive basal cell carcinomas excised by conventional surgery showed that 81 lesions (5.3%) were incompletely excised peripherally; 36 lesions (2.3%) were incompletely excised deeply; 13 lesions (0.8%) were incompletely excised peripherally and deeply.
  • Peripheral histological clearance was <5mm (0.1-4.9mm) for 55% of temple lesions, 50% of scalp lesions and 43% for limb lesions.
  • This study of conventional surgical excision of basal cell carcinomas with an incomplete excision rate of 8% has shown that 65% of lesions were excised with <5mm histological clearance peripherally and 85% with <5mm deep clearance.
  • However, peripheral margins did exceed 5mm in more than 30% of lesions of scalp, temple and forehead, and for these sites where even with loupe magnification the tumour edge could be difficult to define, either frozen section control or Mohs' technique, might with benefit be more often used in order to minimise normal tissue sacrifice.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Skin Neoplasms / surgery

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  • (PMID = 17126265.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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83. Lackey PL, Sargent LA, Wong L, Brzezienski M, Kennedy JW: Giant basal cell carcinoma surgical management and reconstructive challenges. Ann Plast Surg; 2007 Mar;58(3):250-4
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  • [Title] Giant basal cell carcinoma surgical management and reconstructive challenges.
  • Basal cell carcinoma is exceedingly common, but tumors >5 cm in size or giant basal cell carcinomas (GBCCs) are rare.
  • With the exception of 1 chest lesion, all GBCCs involved the face or scalp.
  • The 10 large defects were reconstructed with 5 free-tissue transfers, 2 pedicled musculocutaneous flaps, and 3 rotational skin flaps.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Carcinoma, Giant Cell / pathology. Carcinoma, Giant Cell / surgery. Reconstructive Surgical Procedures / methods

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  • (PMID = 17471127.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Caccialanza M, Piccinno R, Percivalle S, Gnecchi L: Successful use of radiotherapy for radiation-induced basal cell carcinoma of the scalp. Clin Exp Dermatol; 2008 Aug;33(5):660-1
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  • [Title] Successful use of radiotherapy for radiation-induced basal cell carcinoma of the scalp.
  • [MeSH-major] Carcinoma, Basal Cell / radiotherapy. Head and Neck Neoplasms / radiotherapy. Neoplasms, Radiation-Induced / radiotherapy. Scalp. Skin Neoplasms / radiotherapy

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  • [CommentOn] Clin Exp Dermatol. 2007 Jan;32(1):109-11 [17305917.001]
  • (PMID = 18616720.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] England
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85. Chatterjee S, Mott JH, Dickson S, Kelly CG: Extensive basal cell carcinoma of the forehead and anterior scalp: use of helical tomotherapy as a radiotherapy treatment modality. Br J Radiol; 2010 Jun;83(990):538-40
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  • [Title] Extensive basal cell carcinoma of the forehead and anterior scalp: use of helical tomotherapy as a radiotherapy treatment modality.
  • [MeSH-major] Carcinoma, Basal Cell / radiotherapy. Head and Neck Neoplasms / radiotherapy. Radiotherapy, Conformal / methods. Scalp. Skin Neoplasms / radiotherapy

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  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Feb 1;52(2):553-9 [11872304.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1993 Nov 15;27(4):953-8 [8244828.001]
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  • (PMID = 20505036.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3473584
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86. Mathieu D, Fortin D: Intracranial invasion of a basal cell carcinoma of the scalp. Can J Neurol Sci; 2005 Nov;32(4):546-8
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  • [Title] Intracranial invasion of a basal cell carcinoma of the scalp.
  • OBJECTIVE AND IMPORTANCE: Basal cell carcinomas are common lesions that can have a locally invasive behavior.
  • The authors present a case of a scalp lesion with skull and dura-mater invasion that was unrecognized prior to surgical undertaking.
  • CLINICAL PRESENTATION: A 66-year-old female presented with an extensive ulcerating lesion on the frontal scalp, deemed to be a basal cell carcinoma.
  • INTERVENTION: Resection of the invaded frontal scalp, bone, dura-mater and proximal part of the superior sagittal sinus was performed.
  • This was followed by a reconstructive procedure consisting of a duraplasty, a cranioplasty, and a skin rotation flap and partial-thickness skin grafting.
  • CONCLUSION: Radiological evaluation of scalp basal cell carcinomas should be done prior to surgery to rule out any bony or intracranial invasion.
  • [MeSH-major] Bone Neoplasms / pathology. Carcinoma, Basal Cell. Scalp / pathology. Skin Neoplasms. Skull / pathology

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  • (PMID = 16408590.001).
  • [ISSN] 0317-1671
  • [Journal-full-title] The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • [ISO-abbreviation] Can J Neurol Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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87. Bozkurt M, Kapi E, Kuvat SV, Ozekinci S: Current concepts in the management of Marjolin's ulcers: outcomes from a standardized treatment protocol in 16 cases. J Burn Care Res; 2010 Sep-Oct;31(5):776-80
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  • Marjolin's ulcer is a malignant lesion observed in chronic wounds and in areas where the integrity of the skin is compromised because of any one of several reasons.
  • Primary lesions were at the leg, gluteal region, thigh, scalp, trunk, and hand in four (25%), three (18.7%), two (12.5%), two (12.5%), three (18.7%), and two (12.5%) cases, respectively.
  • Amputation was carried out to treat two cases, and repair of the defects with partial-thickness skin grafting was performed in 14 cases after tumor resection on the skin.
  • Squamous cell carcinoma was diagnosed in 14 cases (87.5%) and basal cell carcinoma in two cases (12.5%) postoperatively.
  • The authors conclude that diagnosis and surgical planning based on the recent literature must be carried out even more intensively to improve the prognosis of Marjolin's ulcer.
  • [MeSH-major] Burns / complications. Carcinoma, Basal Cell / etiology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / surgery. Skin Neoplasms / etiology. Skin Neoplasms / surgery. Skin Ulcer / etiology. Skin Ulcer / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Amputation. Female. Humans. Lymph Node Excision. Male. Middle Aged. Neoplasm Recurrence, Local. Skin Transplantation. Treatment Outcome

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  • (PMID = 20661151.001).
  • [ISSN] 1559-0488
  • [Journal-full-title] Journal of burn care & research : official publication of the American Burn Association
  • [ISO-abbreviation] J Burn Care Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Taboada A, Prieto A, Couto I, Brea B, González E: [Invasive basal cell carcinoma of the scalp. A clinical case]. Neurocirugia (Astur); 2010 Oct;21(5):396-400
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  • [Title] [Invasive basal cell carcinoma of the scalp. A clinical case].
  • [Transliterated title] Carinoma basocelular invasivo de cuero cabelludo. Caso clínico.
  • Basal cell carcinoma is the most frequent skin malignant neoplasm, although it doesn't usually compromise a vital risk.
  • We present a 62 years old female operated several times because multifocal basal cell carcinoma on her scalp.
  • [MeSH-major] Brain Neoplasms. Carcinoma, Basal Cell. Head and Neck Neoplasms. Skin Neoplasms

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  • (PMID = 21042691.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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89. Farley R, Ratner D: Diagnosis and management of atypical fibroxanthoma. Skinmed; 2006 Mar-Apr;5(2):83-6
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  • [Title] Diagnosis and management of atypical fibroxanthoma.
  • A 90-year-old Caucasian man with a history of basal cell carcinoma and squamous cell carcinoma presented with a friable erythematous nodule on his scalp that had been present for several months.
  • What is your diagnosis?
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Scalp. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male

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  • (PMID = 16603840.001).
  • [ISSN] 1540-9740
  • [Journal-full-title] Skinmed
  • [ISO-abbreviation] Skinmed
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 43
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90. Lane JE, Goodrich RG, Kent DE, Milde P: Use of Mohs micrographic surgery to treat basal cell carcinoma arising in a nevus sebaceous in an African American patient. J Cutan Med Surg; 2007 Jul-Aug;11(4):158-60
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  • [Title] Use of Mohs micrographic surgery to treat basal cell carcinoma arising in a nevus sebaceous in an African American patient.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Head and Neck Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Nevus / surgery. Scalp. Skin Neoplasms / surgery


91. Filippou DK, Filippou G, Trigka A, Condilis N, Kiparidou E, Skandalakis P, Rizos S: Malignant proliferating trichilemmal tumour of the scalp. Report of a case and a short review of the literature. Ann Ital Chir; 2006 Mar-Apr;77(2):179-81
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  • [Title] Malignant proliferating trichilemmal tumour of the scalp. Report of a case and a short review of the literature.
  • BACKGROUND: Malignant proliferating trichilemmal tumour is a rare skin tumour that originates from the root sheath of the hair and usually arises in the sun-exposed areas of elderly women.
  • It mimicks poorly differential squamous cell carcinoma ant its biological behaviour is unpredictable, because rarely can produce distant metastases.
  • CASE REPORT: The Authors report on a case of a 54-year-old female patients who proceeded with a cystic lesion in the scalp.
  • The appropriate treatment includes wide resection and dose postoperative follow-up of the patient to facilitate the early diagnosis of distant metastases.
  • [MeSH-major] Neoplasms, Basal Cell / surgery. Scalp. Skin Neoplasms / surgery

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  • (PMID = 17147095.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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92. Belmahi A, Oufkir A, Bron T, Ouezzani S: Reconstruction of cheek skin defects by the 'Yin-Yang' rotation of the Mustardé flap and the temporoparietal scalp. J Plast Reconstr Aesthet Surg; 2009 Apr;62(4):506-9
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  • [Title] Reconstruction of cheek skin defects by the 'Yin-Yang' rotation of the Mustardé flap and the temporoparietal scalp.
  • BACKGROUND AND PURPOSES: When the skin's laxity is limited, the preauricular cutaneous defect resulting from the Mustardé cheek rotation flap for the coverage of suborbital skin defects is very difficult to close even with a large undermining of the cervicofacial skin.
  • The rotation of the temporoparietal scalp in an opposite direction compared to the Mustardé flap or the 'Yin-Yang' rotation of these flaps is interesting for two reasons: it allows an easy closure of this preauricular defect with a limited facial undermining and it suspends with efficiency the Mustardé flap at the temporal area avoiding the lower lid's ectropion.
  • MATERIAL AND METHODS: From September 2001 to April 2005, nine patients aged between 35 and 78 years old, with no facial skin laxity, have benefited from this technique to cover suborbital defects secondary to excision of basal cell carcinomas with a mean diameter of 6 cm.
  • The design of the Mustardé flap was classical but the skin undermining stopped at the mandible's lower border.
  • CONCLUSION: This is a good technique for the simple coverage of medium-sized suborbital skin defects.
  • [MeSH-minor] Adult. Aged. Carcinoma, Basal Cell / surgery. Esthetics. Facial Neoplasms / surgery. Female. Follow-Up Studies. Humans. Middle Aged. Scalp / surgery. Skin Neoplasms / surgery. Treatment Outcome

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  • (PMID = 18162448.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article
  • [Publication-country] Netherlands
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93. Nakai N, Takenaka H, Kishimoto S: Atypical fibroxanthoma on a bald scalp. J Dermatol; 2005 Oct;32(10):848-51
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  • [Title] Atypical fibroxanthoma on a bald scalp.
  • We present the clinical, histopathological and immunohistochemical findings of an atypical fibroxanthoma (AFX) on the bald scalp of an 81-year-old French man who had worked at a private high school in Japan as a janitor for over 40 years.
  • The patient had a history of basal cell carcinoma on the nape, and chronic solar radiation seemed to be a predisposing factor in the pathogenesis of this association.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Scalp Dermatoses / pathology
  • [MeSH-minor] Aged, 80 and over. Alopecia / complications. Head and Neck Neoplasms / complications. Head and Neck Neoplasms / pathology. Humans. Male. Scalp. Skin Neoplasms / complications. Skin Neoplasms / pathology

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  • (PMID = 16361741.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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94. Hantash BM, Stewart DB, Cooper ZA, Rehmus WE, Koch RJ, Swetter SM: Facial resurfacing for nonmelanoma skin cancer prophylaxis. Arch Dermatol; 2006 Aug;142(8):976-82
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  • [Title] Facial resurfacing for nonmelanoma skin cancer prophylaxis.
  • OBJECTIVE: To determine the effect of facial skin resurfacing for treatment of actinic keratoses (AKs) and prophylaxis against new primary basal and squamous cell carcinomas in individuals with previous nonmelanoma skin cancer (NMSC) or severe photodamage.
  • PATIENTS: Thirty-four patients with a history of facial or scalp AKs or basal or squamous cell carcinoma were enrolled.
  • Times from baseline to diagnosis of first skin cancer were compared between the treatment and control groups.
  • RESULTS: Treatment with fluorouracil, trichloroacetic acid, or carbon dioxide laser resulted in an 83% to 92% reduction in AKs (P< or =.03), a lower incidence of NMSC compared with the control group (P<.001), and a trend toward longer time to development of new skin cancer compared with the control group (P=.07).
  • CONCLUSION: All 3 modalities demonstrated benefit for AK reduction and skin cancer prophylaxis compared with controls and warrant further study in a larger trial.
  • [MeSH-major] Keratolytic Agents / administration & dosage. Keratosis / prevention & control. Low-Level Light Therapy. Skin Neoplasms / prevention & control
  • [MeSH-minor] Aged. Aged, 80 and over. Carbon Dioxide. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / prevention & control. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / prevention & control. Disease-Free Survival. Drug Administration Schedule. Face. Female. Fluorouracil / administration & dosage. Humans. Male. Middle Aged. Prospective Studies. Scalp. Severity of Illness Index. Treatment Outcome. Trichloroacetic Acid / administration & dosage


95. Heal C, Buettner P, Raasch B, Browning S: Minor skin excisions in general practice in North Queensland. Aust Fam Physician; 2006 Oct;35(10):825-8
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  • [Title] Minor skin excisions in general practice in North Queensland.
  • OBJECTIVE: To describe the demographics of patients presenting with skin cancer to general practitioners in rural North Queensland, the sites from which skin cancers are removed, and their histology.
  • METHODS: Data was recorded from 1247 consecutive patients who attended for minor skin lesion excisions.
  • RESULTS: Close to half (46.7%) of lesions excised were skin cancers.
  • We excised more squamous cell carcinomas than basal cell carcinomas (0.74:1).
  • Mean age for excision of melanoma, basal cell carcinoma and squamous cell carcinoma was 55, 60.9 and 63.8 years respectively.
  • Relative tumour density was greatest in the face, scalp and neck region for all skin cancers.
  • DISCUSSION: In this sample of Mackay GPs, there was a very high yield of skin cancers from all excisions.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Family Practice. Skin Neoplasms / surgery

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  • (PMID = 17019461.001).
  • [ISSN] 0300-8495
  • [Journal-full-title] Australian family physician
  • [ISO-abbreviation] Aust Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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96. Nasir S, Aydin MA: Versatility of free SCIA/SIEA flaps in head and neck defects. Ann Plast Surg; 2010 Jul;65(1):32-7
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  • [MeSH-minor] Adenocarcinoma / surgery. Adolescent. Adult. Aged. Bone Transplantation. Burns / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Child. Cicatrix / surgery. Facial Neoplasms / surgery. Female. Follow-Up Studies. Humans. Male. Maxilla / surgery. Maxillary Neoplasms / surgery. Middle Aged. Neck Injuries / surgery. Neoplasm Recurrence, Local / surgery. Reoperation. Scalp / surgery. Skin Neoplasms / surgery. Young Adult

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  • (PMID = 20574218.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
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97. Terenzi V, Indrizzi E, Buonaccorsi S, Leonardi A, Pellacchia V, Fini G: Nevus sebaceus of Jadassohn. J Craniofac Surg; 2006 Nov;17(6):1234-9
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  • The nevus sebaceus of Jadassohn (SNJ) is a hamartomatous disorder of the skin and its adnexa pertaining to the group of "organoid nevi,'' most frequently involving the face and scalp.
  • It has been largely demonstrated in literature that most of the lesions that have been interpreted as basal cell carcinoma (BCC) are actually examples of primitive follicular induction or trichoblastomas, not authentic BCCs.
  • In one case, the lesion was treated by intraoperative expander-assisted reduction and scalp graft (Case 1); in the other one, a primary closure with adjacent tissue was performed (Case 2).
  • For treatment of the biggest lesions, when preoperative tissue expansion cannot be performed, intraoperative one, transfer of a scalp graft has been shown to be a good reconstructive method.
  • [MeSH-major] Pachyonychia Congenita / pathology. Scalp / pathology. Scalp Dermatoses / pathology

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  • (PMID = 17119437.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 48
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98. Tarallo M, Cigna E, Frati R, Delfino S, Innocenzi D, Fama U, Corbianco A, Scuderi N: Metatypical basal cell carcinoma: a clinical review. J Exp Clin Cancer Res; 2008;27:65
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  • [Title] Metatypical basal cell carcinoma: a clinical review.
  • BACKGROUND: Metatypical cell carcinoma can be considered as a new entity of skin cancer, being an intermediate typology between basal cell carcinomas and squamous cell carcinomas.
  • The behaviour of the metatypical cell carcinoma lies between these two varieties of skin cancer.
  • It is difficult to perform a differential diagnosis based on morphological and clinical features - therefore it is only possible by accurate histology.
  • METHODS: The authors have retrospectively analysed clinical records of 240 patients who were affected by metatypical skin cancer and who were treated by surgery, radiotherapy and chemotherapy.
  • The most affected site was the cervicofacial area, 71.7%; then the trunk, 10%; the limbs, 9.6%; the scalp 3.7%; and other regions 5%.
  • CONCLUSION: In this manuscript, the authors have emphasised the importance of conducting a differential diagnosis, and the importance of the specific treatment for metatypical skin cancer, even though more clinical studies and long-term follow-ups are required before establishing specific guidelines.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Skin Neoplasms / pathology

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  • The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for metatypical basal cell carcinoma .
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  • (PMID = 18992138.001).
  • [ISSN] 1756-9966
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 55
  • [Other-IDs] NLM/ PMC2585560
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99. Patro KC, Padhi S, Singh DN: Squamous cell carcinoma over a nevus: a rare case. J Cancer Res Ther; 2006 Oct-Dec;2(4):200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Squamous cell carcinoma over a nevus: a rare case.
  • Malignant melanoma and basal cell carcinoma are more common over a preexisting nevus.
  • But squamous cell carcinoma over a nevus is a rare phenomenon.
  • A 55-year-old male presented with a slow growing noduloulcerative lesion on a preexisting nevus over scalp.
  • Biopsy came out to be a squamous cell carcinoma with lateral margin positive for tumor.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Nevus / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Brachytherapy. Humans. Male. Middle Aged. Scalp / pathology


100. Sellheyer K, Krahl D: Basal cell (trichoblastic) carcinoma common expression pattern for epithelial cell adhesion molecule links basal cell carcinoma to early follicular embryogenesis, secondary hair germ, and outer root sheath of the vellus hair follicle: A clue to the adnexal nature of basal cell carcinoma? J Am Acad Dermatol; 2008 Jan;58(1):158-67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basal cell (trichoblastic) carcinoma common expression pattern for epithelial cell adhesion molecule links basal cell carcinoma to early follicular embryogenesis, secondary hair germ, and outer root sheath of the vellus hair follicle: A clue to the adnexal nature of basal cell carcinoma?
  • BACKGROUND: Basal cell carcinoma (BCC) is still viewed by many dermatologists as a tumor of the interfollicular epidermis, although references were made early in the dermatopathologic literature to the resemblance of BCC to the hair follicle.
  • OBJECTIVE: Our aim was to characterize the common expression pattern for the epithelial cell adhesion molecule (Ep-CAM) in BCCs, various stages of follicular embryogenesis, and adult hair follicles and, thereby, in analogy point to the similarity between BCC and the hair follicle.
  • In addition, we examined terminal scalp and vellus hair follicles.
  • CONCLUSION: BCC expresses the cell-cell adhesion molecule Ep-CAM similar to the embryonic hair germ, the secondary hair germ of the terminal hair follicle, and the outer root sheath of the vellus hair follicle.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Carcinoma, Basal Cell / metabolism. Cell Adhesion Molecules / metabolism. Hair Follicle / embryology. Hair Follicle / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Adult. Eccrine Glands / embryology. Embryo, Mammalian / metabolism. Embryonic Development. Humans. Immunohistochemistry. Nails / embryology. Scalp

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  • (PMID = 18158927.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Cell Adhesion Molecules; 0 / tumor-associated antigen GA733
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