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1. Dennis R, Zhang HM, Cheng HW: Effect of selection for resistance and susceptibility to viral diseases on concentrations of dopamine and immunological parameters in six-week-old chickens. Poult Sci; 2006 Dec;85(12):2135-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • White Leghorn chickens were inbred respectively from their parent lines, which were diversely selected for resistance (line 6(3)) or susceptibility (lines 7(2) and 15I(5)) to Marek's disease and lymphoid leukosis.
  • The differences in disease resistance may have been due to differential regulation of immune and neuroendocrine homeostasis.
  • These results suggested that genetic selection for disease resistance also directly or indirectly modified the corresponding genetic components that govern the immune and neuroendocrine systems.
  • The genetic lines of chickens may be used as animal models for investigation of the cellular mechanisms of genetic-environmental interactions on disease resistance.
  • [MeSH-minor] Animals. B-Lymphocytes. CD8-Positive T-Lymphocytes. Female. Genetic Predisposition to Disease. Immunoglobulin G / blood. Inbreeding. Male

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  • (PMID = 17135669.001).
  • [ISSN] 0032-5791
  • [Journal-full-title] Poultry science
  • [ISO-abbreviation] Poult. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin G; VTD58H1Z2X / Dopamine
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2. Miyazawa T: [Receptors for animal retroviruses]. Uirusu; 2009 Dec;59(2):223-42
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  • Of retroviruses in veterinary field, receptors for the following viruses have been identified; equine infectious anemia virus, feline immunodeficiency virus, feline leukemia virus subgroups A, B, C, and T, Jaagsiekte sheep retrovirus, enzootic nasal tumor virus, avian leukosis virus subgroups A, B, C, D, E, and J, reticuloendotheliosis virus, RD-114 virus (a feline endogenous retrovirus), and porcine endogenous retrovirus subgroup A.

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  • (PMID = 20218331.001).
  • [ISSN] 0042-6857
  • [Journal-full-title] Uirusu
  • [ISO-abbreviation] Uirusu
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Receptors, Virus
  • [Number-of-references] 116
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3. Zavala G, Cheng S: Detection and characterization of avian leukosis virus in Marek's disease vaccines. Avian Dis; 2006 Jun;50(2):209-15
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  • [Title] Detection and characterization of avian leukosis virus in Marek's disease vaccines.
  • Avian leukosis virus (ALV) infection in chickens is known to induce increased mortality, tumors, delayed growth, and suboptimal egg production.
  • Countries importing specified pathogen-free eggs, vaccines, and poultry breeding stock require freedom of infection or contamination with ALV in such products among other avian pathogens.
  • Our methods are proposed as complementary procedures to the currently required complement fixation for avian leukosis test for detection of ALV in commercial poultry vaccines.
  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Chickens / virology. Drug Contamination. Marek Disease. Poultry Diseases. Viral Vaccines / standards

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  • (PMID = 16863069.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Vaccines
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4. Lehmann MJ, Sherer NM, Marks CB, Pypaert M, Mothes W: Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells. J Cell Biol; 2005 Jul 18;170(2):317-25
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  • [Title] Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells.
  • Viruses have often been observed in association with the dense microvilli of polarized epithelia as well as the filopodia of nonpolarized cells, yet whether interactions with these structures contribute to infection has remained unknown.
  • Here we show that virus binding to filopodia induces a rapid and highly ordered lateral movement, "surfing" toward the cell body before cell entry.
  • Virus cell surfing along filopodia is mediated by the underlying actin cytoskeleton and depends on functional myosin II.
  • Any disruption of virus cell surfing significantly reduces viral infection.
  • Our results reveal another example of viruses hijacking host machineries for efficient infection by using the inherent ability of filopodia to transport ligands to the cell body.

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  • (PMID = 16027225.001).
  • [ISSN] 0021-9525
  • [Journal-full-title] The Journal of cell biology
  • [ISO-abbreviation] J. Cell Biol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA098727; United States / NCI NIH HHS / CA / R01CA098727
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Heterocyclic Compounds with 4 or More Rings; 0 / blebbistatin; 22144-77-0 / Cytochalasin D; EC 3.6.4.1 / Myosins
  • [Other-IDs] NLM/ PMC2171413
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5. Wu X, Li Y, Crise B, Burgess SM, Munroe DJ: Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses. J Virol; 2005 Apr;79(8):5211-4
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  • We carefully examined a large number of integration target site sequences from several retroviruses, including human immunodeficiency virus type 1, simian immunodeficiency virus, murine leukemia virus, and avian sarcoma-leukosis virus, and found that a statistical palindromic consensus, centered on the virus-specific duplicated target site sequence, was a common feature at integration target sites for these retroviruses.

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  • (PMID = 15795304.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / N01CO12400; United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
  • [Other-IDs] NLM/ PMC1069554
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6. Fadly A, Silva R, Hunt H, Pandiri A, Davis C: Isolation and characterization of an adventitious avian leukosis virus isolated from commercial Marek's disease vaccines. Avian Dis; 2006 Sep;50(3):380-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolation and characterization of an adventitious avian leukosis virus isolated from commercial Marek's disease vaccines.
  • Commercial Marek's disease (MD) vaccines produced by two manufacturers were tested for possible contamination with avian leukosis virus (ALV).
  • GenBank accession numbers: The gp85 gene sequences of ALV isolated from commercial Marek's disease vaccines have been deposited in GenBank and assigned the following accession numbers: A46 subgroup A, DQ412726 ; B53 subgroup A, DQ412727; A46 subgroup E, DQ412728; B53 subgroup E, DQ412729.
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / isolation & purification. Chickens / virology. Drug Contamination. Marek Disease Vaccines / analysis

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  • (PMID = 17039837.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ DQ412726/ DQ412727/ DQ412728/ DQ412729
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Marek Disease Vaccines
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7. Hu J, Renaud G, Gomes TJ, Ferris A, Hendrie PC, Donahue RE, Hughes SH, Wolfsberg TG, Russell DW, Dunbar CE: Reduced genotoxicity of avian sarcoma leukosis virus vectors in rhesus long-term repopulating cells compared to standard murine retrovirus vectors. Mol Ther; 2008 Sep;16(9):1617-23
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  • [Title] Reduced genotoxicity of avian sarcoma leukosis virus vectors in rhesus long-term repopulating cells compared to standard murine retrovirus vectors.
  • In this study, we report for the first time a systematic analysis of 198 avian sarcoma leukosis virus (ASLV) insertion sites identified in rhesus long-term repopulating cells, and a comparison of ASLV insertion patterns to Moloney murine leukemia virus (MLV) (n = 396) and simian immunodeficiency virus (SIV) (n = 289) using the newly released rhesus genome databank.
  • [MeSH-major] Avian Leukosis Virus / genetics. Avian Sarcoma Viruses / genetics. Genetic Vectors / genetics. Hematopoietic Stem Cells / metabolism. Moloney murine leukemia virus / genetics. Transduction, Genetic. Virus Integration

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  • (PMID = 18578011.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 HL002339-16; United States / Intramural NIH HHS / / Z99 HL999999
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MDS1-EVI1 fusion protein, mouse; 0 / Oncogene Proteins, Fusion
  • [Other-IDs] NLM/ NIHMS51855; NLM/ PMC2561952
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8. Mays JK, Pandiri AR, Fadly AM: Susceptibility of various parental lines of commercial white leghorn layers to infection with a naturally occurring recombinant avian leukosis virus containing subgroup B envelope and subgroup J long terminal repeat. Avian Dis; 2006 Sep;50(3):342-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Susceptibility of various parental lines of commercial white leghorn layers to infection with a naturally occurring recombinant avian leukosis virus containing subgroup B envelope and subgroup J long terminal repeat.
  • Chickens from seven different parental lines of commercial White Leghorn layer flocks from three independent breeders were inoculated with a naturally occurring avian leukosis virus (ALV) containing an ALV-B envelope and an ALV-J long terminal repeat (LTR) termed ALV-B/J.
  • Infection with the ALV-B/J recombinant virus at embryonation and at hatch induced predominately lymphoid leukosis (LL), along with other common ALV neoplasms, including erythroblastosis, osteopetrosis, nephroblastomas, and rhabdosarcomas.
  • No incidence of myeloid leukosis (ML) was observed in any of the commercial White Leghorn egg layer flocks infected with ALV-B/J in the present study.
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / genetics. Chickens / virology. Genetic Predisposition to Disease. Terminal Repeat Sequences / genetics. Viral Envelope Proteins / genetics

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  • (PMID = 17039832.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Envelope Proteins
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9. Mortuza GB, Goldstone DC, Pashley C, Haire LF, Palmarini M, Taylor WR, Stoye JP, Taylor IA: Structure of the capsid amino-terminal domain from the betaretrovirus, Jaagsiekte sheep retrovirus. J Mol Biol; 2009 Mar 06;386(4):1179-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We find that the structure is remarkably similar to the amino-terminal domain of the alpharetrovirus, avian leukosis virus, revealing a previously undetected evolutionary similarity.

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  • (PMID = 19007792.001).
  • [ISSN] 1089-8638
  • [Journal-full-title] Journal of molecular biology
  • [ISO-abbreviation] J. Mol. Biol.
  • [Language] eng
  • [Databank-accession-numbers] PDB/ 2V4X
  • [Grant] United Kingdom / Medical Research Council / / MC/ U117512710; United Kingdom / Medical Research Council / / MC/ U117565647; United Kingdom / Medical Research Council / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Capsid Proteins; 0 / Solutions
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10. Côté M, Zheng YM, Liu SL: Receptor binding and low pH coactivate oncogenic retrovirus envelope-mediated fusion. J Virol; 2009 Nov;83(22):11447-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fusion of enveloped viruses with host cells is triggered by either receptor binding or low pH but rarely requires both except for avian sarcoma leukosis virus (ASLV).

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  • (PMID = 19726505.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] Canada / Canadian Institutes of Health Research / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Virus; 0 / Viral Fusion Proteins
  • [Other-IDs] NLM/ PMC2772678
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11. Markosyan RM, Kielian M, Cohen FS: Fusion induced by a class II viral fusion protein, semliki forest virus E1, is dependent on the voltage of the target cell. J Virol; 2007 Oct;81(20):11218-25
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  • In contrast, fusion induced by the class I fusion proteins of human immunodeficiency virus, avian sarcoma leukosis virus, and influenza virus was independent of the voltage polarity across the target cell.

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  • (PMID = 17686870.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM027367; United States / NIGMS NIH HHS / GM / R01 GM057454; United States / NIGMS NIH HHS / GM / GM057454; United States / NIGMS NIH HHS / GM / R01 GM27367
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Envelope Proteins; 0 / Viral Fusion Proteins
  • [Other-IDs] NLM/ PMC2045574
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12. Asimakopoulos F, Varmus HE: Cell-specific transduction of Prdm1-expressing lineages mediated by a receptor for avian leukosis virus subgroup B. J Virol; 2009 May;83(10):4835-43
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  • [Title] Cell-specific transduction of Prdm1-expressing lineages mediated by a receptor for avian leukosis virus subgroup B.
  • We created bacterial artificial chromosome-transgenic mice expressing the avian leukosis virus (ALV) receptor TVB, fused to monomeric red fluorescent protein, under regulation by Prdm1 transcriptional elements, and we achieved transduction of TVB-expressing lymphocytes by ALV vectors bearing a subgroup B envelope.

  • SciCrunch. OMIA - Online Mendelian Inheritance in Animals: Data: Gene Expression .
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  • (PMID = 19279099.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01 CA105492; United States / NCI NIH HHS / CA / U01CA105492
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Luminescent Proteins; 0 / Prdm1 protein, mouse; 0 / Receptors, Virus; 0 / Transcription Factors; 0 / red fluorescent protein
  • [Other-IDs] NLM/ PMC2682090
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13. Melikyan GB, Barnard RJ, Abrahamyan LG, Mothes W, Young JA: Imaging individual retroviral fusion events: from hemifusion to pore formation and growth. Proc Natl Acad Sci U S A; 2005 Jun 14;102(24):8728-33
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  • To elucidate the mechanism of virus entry, we have imaged fusion between single virions bearing avian sarcoma and leukosis virus (ASLV) envelope glycoprotein (Env) and the cell membrane.

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  • (PMID = 15937118.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI053668; United States / NCI NIH HHS / CA / R01 CA098727; United States / NIAID NIH HHS / AI / AI053668; United States / NCI NIH HHS / CA / CA098727
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fluorescent Dyes; 0 / Viral Envelope Proteins; 0 / Viral Fusion Proteins
  • [Other-IDs] NLM/ PMC1150829
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14. Corrigendum to "Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors". Mol Ther; 2008 Oct;16(10):1770
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  • [Title] Corrigendum to "Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors".

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  • (PMID = 28189005.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Published Erratum
  • [Publication-country] United States
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15. Shukshina IZ, Miniat EE: [Dimerization of short RNA fragments from avian leukosis virus as revealed with 2-aminopurine fluorescence]. Mol Biol (Mosk); 2008 Jan-Feb;42(1):131-7
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  • [Title] [Dimerization of short RNA fragments from avian leukosis virus as revealed with 2-aminopurine fluorescence].
  • The 5'-end sequences from RNA avian viruses, where the dimers are basically formed, considerably differ from those of HIV.
  • However, as it was described earlier, the mechanism of dimerization of RNA from human immunodeficiency and from avian leukosis viruses are identical.
  • [MeSH-major] 2-Aminopurine / chemistry. 5' Untranslated Regions / chemistry. Avian Leukosis Virus / chemistry. RNA, Double-Stranded / chemistry. RNA, Viral / chemistry

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  • (PMID = 18389630.001).
  • [ISSN] 0026-8984
  • [Journal-full-title] Molekuliarnaia biologiia
  • [ISO-abbreviation] Mol. Biol. (Mosk.)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / 5' Untranslated Regions; 0 / Anti-Bacterial Agents; 0 / RNA, Double-Stranded; 0 / RNA, Viral; 452-06-2 / 2-Aminopurine; 61JJC8N5ZK / Paromomycin
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16. Senigl F, Plachý J, Hejnar J: The core element of a CpG island protects avian sarcoma and leukosis virus-derived vectors from transcriptional silencing. J Virol; 2008 Aug;82(16):7818-27
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  • [Title] The core element of a CpG island protects avian sarcoma and leukosis virus-derived vectors from transcriptional silencing.
  • We report here the insertion of this CpG island core element, IE, into the long terminal repeat of a retroviral vector derived from Rous sarcoma virus, which normally suffers from progressive transcriptional silencing in mammalian cells.
  • [MeSH-major] Avian Leukosis Virus / metabolism. CpG Islands. Gene Silencing. Sarcoma, Avian / genetics. Sarcoma, Avian / virology. Transcription, Genetic
  • [MeSH-minor] Animals. Binding Sites. Birds. Flow Cytometry. Genes, Reporter. Humans. Models, Biological. Mutation. Rous sarcoma virus / metabolism. Sp1 Transcription Factor / metabolism. Terminal Repeat Sequences

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  • (PMID = 18550662.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sp1 Transcription Factor
  • [Other-IDs] NLM/ PMC2519551
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17. Chen M, Payne WS, Hunt H, Zhang H, Holmen SL, Dodgson JB: Inhibition of Marek's disease virus replication by retroviral vector-based RNA interference. Virology; 2008 Aug 1;377(2):265-72
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  • [Title] Inhibition of Marek's disease virus replication by retroviral vector-based RNA interference.
  • In this study, similar RNAi vectors are shown to inhibit replication of the avian herpesvirus, Marek's disease virus (MDV, also known as gallid herpesvirus type 2), and its close relative, herpesvirus of turkeys (HVT).
  • [MeSH-major] Avian Leukosis Virus / drug effects. MicroRNAs / pharmacology. RNA Interference. Retroviridae / metabolism. Viral Proteins / metabolism. Virus Replication / drug effects
  • [MeSH-minor] Animals. Genetic Vectors. Marek Disease / prevention & control. Marek Disease / virology. Viral Plaque Assay / veterinary

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  • (PMID = 18570965.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs; 0 / Viral Proteins
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18. Laakso MM, Sutton RE: Replicative fidelity of lentiviral vectors produced by transient transfection. Virology; 2006 May 10;348(2):406-17
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  • Using a single cycle reversion assay, we unexpectedly found that the reversion rates of HIV, avian leukosis virus and Moloney murine leukemia virus were the same, within statistical error.
  • [MeSH-minor] Animals. Avian Leukosis Virus / genetics. Avian Leukosis Virus / physiology. Base Sequence. Cell Line. DNA, Viral / genetics. Escherichia coli / genetics. HIV / genetics. HIV / physiology. HeLa Cells. Humans. Membrane Fusion. Moloney murine leukemia virus / genetics. Moloney murine leukemia virus / physiology. Plasmids / genetics. RNA Polymerase II / metabolism. Species Specificity. Temperature. Virus Replication / genetics

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  • (PMID = 16469344.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / T32 AI07471
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; EC 2.7.7.- / RNA Polymerase II
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19. Yang F, Xian RR, Li Y, Polony TS, Beemon KL: Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas. Proc Natl Acad Sci U S A; 2007 Nov 27;104(48):18952-7
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  • [Title] Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas.
  • In this study, we identified avian leukosis virus (ALV) proviral integration sites in rapid-onset B cell lymphomas arising <12 weeks after infection of chicken embryos.

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  • (PMID = 18024587.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA048746; United States / NCI NIH HHS / CA / R01 CA124596; United States / NIGMS NIH HHS / GM / T32 GM007231; United States / NCI NIH HHS / CA / R01 CA48746
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm; EC 2.7.7.49 / Telomerase
  • [Other-IDs] NLM/ PMC2141889
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20. Zhang QC, Zhao DM, Guo HJ, Cui ZZ: Isolation and identification of a subgroup A avian leukosis virus from imported meat-type grand-parent chickens. Virol Sin; 2010 Apr;25(2):130-6
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  • [Title] Isolation and identification of a subgroup A avian leukosis virus from imported meat-type grand-parent chickens.
  • An exogenous avian leukosis virus (ALV) strain SDAU09C1 was isolated in DF-1 cells from one of 240 imported 1-day-old white meat-type grand parent breeder chicks.
  • [MeSH-major] Avian Leukosis / diagnosis. Avian Leukosis Virus / isolation & purification. Chickens / virology

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  • (PMID = 20960310.001).
  • [ISSN] 1995-820X
  • [Journal-full-title] Virologica Sinica
  • [ISO-abbreviation] Virol Sin
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Viral Envelope Proteins; 0 / glycoprotein 85, avian leukosis virus
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21. Maas R, van Zoelen D, Oei H, Claassen I: Replacement of primary chicken embryonic fibroblasts (CEF) by the DF-1 cell line for detection of avian leucosis viruses. Biologicals; 2006 Sep;34(3):177-81
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  • [Title] Replacement of primary chicken embryonic fibroblasts (CEF) by the DF-1 cell line for detection of avian leucosis viruses.
  • International regulations prescribe that the absence of avian leucosis viruses (ALV) in avian live virus vaccines has to be demonstrated.
  • (1) in titration experiments without cell passage, (2) in experiments with passages in cell cultures according to European Pharmacopoeia requirements, and (3) in experiments with commercial live avian vaccines that had been spiked with known amounts of ALV.
  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Cell Line. Viral Vaccines / standards

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  • (PMID = 16257542.001).
  • [ISSN] 1045-1056
  • [Journal-full-title] Biologicals : journal of the International Association of Biological Standardization
  • [ISO-abbreviation] Biologicals
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Viral Vaccines
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22. Klopocki E, Hennig BP, Dathe K, Koll R, de Ravel T, Baten E, Blom E, Gillerot Y, Weigel JF, Krüger G, Hiort O, Seemann P, Mundlos S: Deletion and point mutations of PTHLH cause brachydactyly type E. Am J Hum Genet; 2010 Mar 12;86(3):434-9
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  • On the basis of our initial finding, we tested further individuals with BDE and short stature for mutations in PTHLH.
  • The missense mutation L60P was tested in chicken micromass culture with the replication-competent avian sarcoma leukosis virus retroviral expression system and was shown to result in a loss of function.
  • [MeSH-minor] Animals. Cells, Cultured. Chick Embryo. Codon, Nonsense. Disease Models, Animal. Female. Foot Deformities, Congenital / genetics. Foot Deformities, Congenital / pathology. Genes, Dominant. Growth Disorders / genetics. Growth Disorders / pathology. Hand Deformities, Congenital / genetics. Hand Deformities, Congenital / pathology. Humans. Male. Mice. Mice, Knockout. Mutation, Missense. Pedigree. Phenotype. Point Mutation. Recombinant Proteins / genetics. Recombinant Proteins / metabolism. Sequence Deletion


23. Chang CM, Coville JL, Coquerelle G, Gourichon D, Oulmouden A, Tixier-Boichard M: Complete association between a retroviral insertion in the tyrosinase gene and the recessive white mutation in chickens. BMC Genomics; 2006;7:19
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  • Molecular cloning and sequencing results showed the insertion of a complete avian retroviral sequence of the Avian Leukosis Virus (ALV) family.
  • CONCLUSION: In this study, we conclude that the insertion of a complete avian retroviral sequence in intron 4 of the tyrosinase gene is diagnostic of the recessive white mutation in chickens.
  • [MeSH-major] Avian Leukosis Virus / genetics. Chickens / genetics. Chickens / virology. Genes, Recessive. Monophenol Monooxygenase / genetics. Pigmentation / genetics

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  • (PMID = 16457736.001).
  • [ISSN] 1471-2164
  • [Journal-full-title] BMC genomics
  • [ISO-abbreviation] BMC Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 9007-49-2 / DNA; EC 1.14.18.1 / Monophenol Monooxygenase
  • [Other-IDs] NLM/ PMC1373650
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24. Torne-Celer C, Moreau K, Faure C, Verdier G, Ronfort C: An improved self-deleting retroviral vector derived from avian leukemia and sarcoma virus. Arch Virol; 2008;153(12):2233-43
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  • [Title] An improved self-deleting retroviral vector derived from avian leukemia and sarcoma virus.
  • We have previously developed a self-deleting avian leukosis and sarcoma virus (ALSV)- based retroviral vector carrying an additional attachment (att) sequence.

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  • (PMID = 19018452.001).
  • [ISSN] 1432-8798
  • [Journal-full-title] Archives of virology
  • [ISO-abbreviation] Arch. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Austria
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25. Sironi G, Manarolla G, Pisoni G, Recordati C, Rampin T: Myotropic avian leukosis virus subgroup J infection in a chicken. J Vet Med B Infect Dis Vet Public Health; 2006 Sep;53(7):347-9
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  • [Title] Myotropic avian leukosis virus subgroup J infection in a chicken.
  • The study describes a highly productive myotropic avian leukosis virus infection (ALV) in a 3-month-old female chicken.
  • Immunostaining for ALV group specific antigen p27 revealed a diffuse presence of virus antigen in cardiac myofibers, in smooth muscle fibers of most of the organs, and in rare, pancreatic and ovarian theca cells.
  • [MeSH-major] Avian Leukosis / pathology. Avian Leukosis Virus / isolation & purification. Chickens. Poultry Diseases / pathology

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  • (PMID = 16930280.001).
  • [ISSN] 0931-1793
  • [Journal-full-title] Journal of veterinary medicine. B, Infectious diseases and veterinary public health
  • [ISO-abbreviation] J. Vet. Med. B Infect. Dis. Vet. Public Health
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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26. Victoria JG, Wang C, Jones MS, Jaing C, McLoughlin K, Gardner S, Delwart EL: Viral nucleic acids in live-attenuated vaccines: detection of minority variants and an adventitious virus. J Virol; 2010 Jun;84(12):6033-40
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  • The anticipated detection of endogenous retroviral sequences from the producer avian and primate cells was confirmed.
  • Avian leukosis virus (ALV), previously shown to be noninfectious for humans, was present as RNA in viral particles, while simian retrovirus (SRV) was present as genetically defective DNA.


27. Chai N, Bates P: Na+/H+ exchanger type 1 is a receptor for pathogenic subgroup J avian leukosis virus. Proc Natl Acad Sci U S A; 2006 Apr 4;103(14):5531-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Na+/H+ exchanger type 1 is a receptor for pathogenic subgroup J avian leukosis virus.
  • Subgroup J avian leukosis virus (ALV-J) is a recently identified avian oncogenic retrovirus responsible for severe economic losses worldwide.
  • In contrast with the other ALV subgroups, ALV-J predominantly induces myeloid leukosis in meat-type chickens.
  • Pathogenicity and myeloid leukosis induction map to the env gene of ALV-J.

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  • (PMID = 16567631.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Databank-accession-numbers] GENBANK/ DQ256198
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI043455; United States / NIAID NIH HHS / AI / R01 AI076256; United States / NIAID NIH HHS / AI / R01 AI 44355; United States / NIAID NIH HHS / AI / R21 AI059172; United States / NCI NIH HHS / CA / R01 CA076256; United States / NIAID NIH HHS / AI / R21 AI 059172; United States / NCI NIH HHS / CA / R01 CA 76256
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cation Transport Proteins; 0 / Membrane Proteins; 0 / Receptors, Virus; 0 / SLC9A1 protein, human; 0 / Sodium-Hydrogen Antiporter
  • [Other-IDs] NLM/ PMC1459389
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28. Zhang XY, Kutner RH, Bialkowska A, Marino MP, Klimstra WB, Reiser J: Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/leukosis virus. Retrovirology; 2010 Jan 25;7:3
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  • [Title] Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/leukosis virus.
  • An alternative approach involved soluble avian sarcoma/leukosis virus receptors fused to cell-specific ligands including stem cell factor and erythropoietin for targeting lentiviral vectors pseudotyped with avian sarcoma/leukosis virus envelope proteins to cells that express the corresponding receptors.
  • Lentiviral vectors pseudotyped with avian sarcoma/leukosis virus subgroup A or B envelope proteins and bearing bi-functional bridge proteins encoding erythropoietin or stem cell factor fused to the soluble extracellular domains of the avian sarcoma/leukosis virus subgroup A or B receptors resulted in efficient transduction of erythropoietin receptor or c-kit-expressing cells.
  • CONCLUSIONS: Our results indicate that the avian sarcoma/leukosis virus bridge strategy provides a reliable approach for cell-specific lentiviral vector targeting.

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  • (PMID = 20100344.001).
  • [ISSN] 1742-4690
  • [Journal-full-title] Retrovirology
  • [ISO-abbreviation] Retrovirology
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / NS044832
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Viral Fusion Proteins
  • [Other-IDs] NLM/ PMC2823649
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29. Toyoda T, Ochiai K, Hatai H, Murakami M, Ono E, Kimura T, Umemura T: Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. Vet Pathol; 2006 May;43(3):294-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma.
  • Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis virus (ALV), shows tumorigenicity and pathogenicity, mainly in the nervous system, and causes astrocytoma and perineurioma.
  • [MeSH-major] Avian Leukosis Virus / pathogenicity. Cerebellar Diseases / veterinary. Cerebellum / pathology. Glioma / veterinary. Poultry Diseases / pathology. Poultry Diseases / virology

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  • (PMID = 16672576.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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30. Bu W, Xin L, Toneff M, Li L, Li Y: Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo. J Mammary Gland Biol Neoplasia; 2009 Dec;14(4):401-4
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  • We have reported the use of vectors based on avian leukosis virus (ALV) and ALV env pseudotyped lentivirus for stably introducing genes into somatic mammary cells in vivo for tumor modeling.

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  • (PMID = 19936990.001).
  • [ISSN] 1573-7039
  • [Journal-full-title] Journal of mammary gland biology and neoplasia
  • [ISO-abbreviation] J Mammary Gland Biol Neoplasia
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA091029; United States / NCI NIH HHS / CA / R01 CA113869; United States / NCI NIH HHS / CA / R01 CA127945; United States / NCI NIH HHS / CA / CA113869
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  • [Publication-country] United States
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31. Hope TJ: Bridging efficient viral infection. Nat Cell Biol; 2007 Mar;9(3):243-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Animals. Avian Leukosis Virus / physiology. Biological Transport. Endocytosis / physiology. HIV-1 / physiology. Humans. Leukemia Virus, Murine / physiology. Models, Biological. Receptors, Virus / metabolism. Viral Envelope Proteins / metabolism

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  • [CommentOn] Nat Cell Biol. 2007 Mar;9(3):310-5 [17293854.001]
  • (PMID = 17330113.001).
  • [ISSN] 1465-7392
  • [Journal-full-title] Nature cell biology
  • [ISO-abbreviation] Nat. Cell Biol.
  • [Language] eng
  • [Publication-type] Comment; News
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Receptors, Virus; 0 / Viral Envelope Proteins
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32. Barbosa T, Zavala G, Cheng S: Molecular characterization of three recombinant isolates of avian leukosis virus obtained from contaminated Marek's disease vaccines. Avian Dis; 2008 Jun;52(2):245-52
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  • [Title] Molecular characterization of three recombinant isolates of avian leukosis virus obtained from contaminated Marek's disease vaccines.
  • Three natural recombinant avian leukosis viruses (ALV; PDRC-1039, PDRC-3246, and PDRC-3249) expressing a subgroup A gp85 envelope protein and containing long terminal repeats (LTR) of endogenous ALV-E viruses were isolated from contaminated commercial Marek's disease vaccines, cloned, and completely sequenced.
  • [MeSH-major] Avian Leukosis Virus / genetics. Avian Leukosis Virus / isolation & purification. Marek Disease Vaccines / genetics

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  • (PMID = 18646453.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ EU070900/ EU070901/ EU070902
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Viral; 0 / Marek Disease Vaccines; 0 / Viral Envelope Proteins; 0 / glycoprotein 85, avian leukosis virus
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33. Zhang JY, Cui ZZ, Ding JB, Jiang SJ: [Construction of infectious clone of subgroup J avian leukosis virus strain NX0101 and its pathogenicity]. Wei Sheng Wu Xue Bao; 2005 Jun;45(3):437-40
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  • [Title] [Construction of infectious clone of subgroup J avian leukosis virus strain NX0101 and its pathogenicity].
  • By using PCR, 3 fragments of provirus cDNA of avian leukosis virus (ALV-J) strain NXO101 were amplified from the genomic DNA of ALV-J infected cells,and then combined in the right direction and sequences into recombinant plasmid pALV-J-NX, containing the whole genome of NX0101.
  • [MeSH-major] Avian Leukosis Virus / genetics. Avian Leukosis Virus / pathogenicity. DNA, Viral / genetics. Plasmids / genetics

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  • (PMID = 15989242.001).
  • [ISSN] 0001-6209
  • [Journal-full-title] Wei sheng wu xue bao = Acta microbiologica Sinica
  • [ISO-abbreviation] Wei Sheng Wu Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / DNA, Complementary; 0 / DNA, Viral
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34. Barnard RJ, Elleder D, Young JA: Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane fusion. Virology; 2006 Jan 5;344(1):25-9
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  • [Title] Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane fusion.
  • For over 40 years, avian sarcoma and leukosis virus (ASLV)-receptor interactions have been employed as a useful model system to study the mechanism of retroviral entry into cells.
  • [MeSH-major] Avian Leukosis Virus / metabolism. Receptors, Virus / metabolism. Sarcoma, Avian / virology. Viral Fusion Proteins / metabolism

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  • (PMID = 16364732.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Virus; 0 / Viral Fusion Proteins; 0 / Viral Proteins
  • [Number-of-references] 32
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35. Zhang HM, Bacon LD, Cheng HH, Hunt HD: Development and validation of a PCR-RFLP assay to evaluate TVB haplotypes coding receptors for subgroup B and subgroup E avian leukosis viruses in White Leghorns. Avian Pathol; 2005 Aug;34(4):324-31
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  • [Title] Development and validation of a PCR-RFLP assay to evaluate TVB haplotypes coding receptors for subgroup B and subgroup E avian leukosis viruses in White Leghorns.
  • The cellular receptor of subgroup B avian leukosis virus (ALVB) is encoded by a gene at the tumour virus B (TVB) locus.
  • TVB alleles encode specific receptors permitting infection by exogenous ALVB or avian leukosis virus subgroup D (ALVD) as well as endogenous avian leukosis virus subgroup E (ALVE), and thus susceptibility is dominant to resistance.
  • Chickens from parents heterozygous for different TVB alleles were challenged with Rous sarcoma viruses of subgroup ALVB and ALVE to induce wing-web tumours.
  • [MeSH-major] Avian Leukosis Virus. Avian Proteins / genetics. Chickens / genetics. Polymerase Chain Reaction / methods. Receptors, Virus / genetics
  • [MeSH-minor] Alleles. Animals. Avian Sarcoma Viruses. Haplotypes. Polymorphism, Restriction Fragment Length. Sarcoma, Avian / virology

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  • (PMID = 16147569.001).
  • [ISSN] 0307-9457
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Avian Proteins; 0 / Receptors, Virus
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36. Bruce JW, Hierl M, Young JA, Ahlquist P: Cellular transcription factor ZASC1 regulates murine leukemia virus transcription. J Virol; 2010 Aug;84(15):7473-83
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  • The defect in this cell line was specific for the MLV long terminal repeat (LTR) promoter, as normal levels of reporter gene expression were obtained from both an internal cytomegalovirus (CMV) promoter contained within an LTR-defective MLV vector and LTR expression from an avian sarcoma and leukosis virus (ASLV) vector.

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  • (PMID = 20484494.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / AI072645-05; United States / NIAID NIH HHS / AI / AI72645; United States / NIAID NIH HHS / AI / R01 AI072645; United States / NIAID NIH HHS / AI / R01 AI072645-05; United States / Howard Hughes Medical Institute / / ; United States / NCI NIH HHS / CA / P01 CA022443; United States / NCI NIH HHS / CA / CA22443
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transcription Factors
  • [Other-IDs] NLM/ PMC2897642
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37. Torne-Celer C, Moreau K, Faure C, Chebloune Y, Verdier G, Ronfort C: A novel self-deleting retroviral vector carrying an additional sequence recognized by the viral integrase (IN). Virus Res; 2008 Jul;135(1):72-82
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  • We have developed a self-deleting Avian Leukosis and Sarcoma Viruses (ALSVs)-based retroviral vector carrying an additional copy of the att sequence, between neo and puro genes.

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  • (PMID = 18420298.001).
  • [ISSN] 0168-1702
  • [Journal-full-title] Virus research
  • [ISO-abbreviation] Virus Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / RNA, Viral; 0 / Viral Proteins; EC 2.7.7.- / Integrases
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38. Gibelin N, Dupont D, Imbert S, Rozet E: Use of Total Error concept in the validation of viral activity in cell cultures. J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Aug 1;877(23):2407-11
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  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Enzyme-Linked Immunosorbent Assay / methods. Fibroblasts / virology

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  • (PMID = 19171505.001).
  • [ISSN] 1873-376X
  • [Journal-full-title] Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  • [ISO-abbreviation] J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Netherlands
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39. Ochi A, Ochiai K, Hatai H, Umemura T: Naturally occurring multiple perineuriomas in a chicken (Gallus domesticus). Vet Pathol; 2008 Sep;45(5):685-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Animals. Avian Leukosis / pathology. Avian Leukosis / virology. Avian Leukosis Virus / genetics. Avian Leukosis Virus / growth & development. Fatal Outcome. Immunohistochemistry / veterinary. Male. RNA, Viral / chemistry. RNA, Viral / genetics. Reverse Transcriptase Polymerase Chain Reaction / veterinary

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  • (PMID = 18725474.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Viral
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40. Faschinger A, Rouault F, Sollner J, Lukas A, Salmons B, Günzburg WH, Indik S: Mouse mammary tumor virus integration site selection in human and mouse genomes. J Virol; 2008 Feb;82(3):1360-7
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  • Viruses that comprise the first group, murine leukemia virus and foamy virus, integrate preferentially near transcription start sites.
  • The second group, notably human immunodeficiency virus and simian immunodeficiency virus, preferentially targets transcription units.
  • Avian sarcoma-leukosis virus (ASLV) and human T-cell leukemia virus (HTLV), forming the third group, show little preference for any genomic feature.

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  • (PMID = 18032509.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ EU018613/ EU018614/ EU018615/ EU018616/ EU018617/ EU018618/ EU018619/ EU018620/ EU018621/ EU018622/ EU018623/ EU018624/ EU018625/ EU018626/ EU018627/ EU018628/ EU018629/ EU018630/ EU018631/ EU018632/ EU018633/ EU018634/ EU018635/ EU018636/ EU018637/ EU018638/ EU018639/ EU018640/ EU018641/ EU018642/ EU018643/ EU018644/ EU018645/ EU018646/ EU018647/ EU018648/ EU018649/ EU018650/ EU018651/ EU018652/ EU018653/ EU018654/ EU018655/ EU018656/ EU018657/ EU018658/ EU018659/ EU018660/ EU018661/ EU018662/ EU018663/ EU018664/ EU018665/ EU018666/ EU018667/ EU018668/ EU018669/ EU018670/ EU018671/ EU018672/ EU018673/ EU018674/ EU018675/ EU018676/ EU018677/ EU018678/ EU018679/ EU018680/ EU018681/ EU018682/ EU018683/ EU018684/ EU018685/ EU018686/ EU018687/ EU018688/ EU018689/ EU018690/ EU018691/ EU018692/ EU018693/ EU018694/ EU018695/ EU018696/ EU018697/ EU018698/ EU018699/ EU018700/ EU018701/ EU018702/ EU018703/ EU018704/ EU018705/ EU018706/ EU018707/ EU018708/ EU018709/ EU018710/ EU018711/ EU018712/ EU018713/ EU018714/ EU018715/ EU018716/ EU018717/ EU018718/ EU018719/ EU018720/ EU018721/ EU018722/ EU018723/ EU018724/ EU018725/ EU018726/ EU018727/ EU018728/ EU018729/ EU018730/ EU018731/ EU018732/ EU018733/ EU018734/ EU018735/ EU018736/ EU018737/ EU018738/ EU018739/ EU018740/ EU018741/ EU018742/ EU018743/ EU018744/ EU018745/ EU018746/ EU018747/ EU018748/ EU018749/ EU018750/ EU018751/ EU018752/ EU018753/ EU018754/ EU018755/ EU018756/ EU018757/ EU018758/ EU018759/ EU018760/ EU018761/ EU018762/ EU018763/ EU018764/ EU018765/ EU018766/ EU018767/ EU018768/ EU018769/ EU018770/ EU018771/ EU018772/ EU018773/ EU018774/ EU018775/ EU018776/ EU018777/ EU018778/ EU018779/ EU018780/ EU018781/ EU018782/ EU018783/ EU018784/ EU018785/ EU018786/ EU018787/ EU018788/ EU018789/ EU018790/ EU018791/ EU018792/ EU018793/ EU018794/ EU018795/ EU018796/ EU018797/ EU018798/ EU018799/ EU018800/ EU018801/ EU018802/ EU018803/ EU018804/ EU018805/ EU018806/ EU018807/ EU018808/ EU018809/ EU018810/ EU018811/ EU018812/ EU018813/ EU018814/ EU018815/ EU018816/ EU018817/ EU018818/ EU018819/ EU018820/ EU018821/ EU018822/ EU018823/ EU018824/ EU018825/ EU018826/ EU018827/ EU018828/ EU018829/ EU018830/ EU018831/ EU018832/ EU018833/ EU018834/ EU018835/ EU018836/ EU018837/ EU018838/ EU018839/ EU018840/ EU018841/ EU018842/ EU018843/ EU018844/ EU018845/ EU018846/ EU018847/ EU018848/ EU018849/ EU018850/ EU018851/ EU018852/ EU018853/ EU018854/ EU018855/ EU018856/ EU018857/ EU018858/ EU018859/ EU018860/ EU018861/ EU018862/ EU018863/ EU018864/ EU018865/ EU018866/ EU018867/ EU018868/ EU018869/ EU018870/ EU018871/ EU018872/ EU018873/ EU018874/ EU018875/ EU018876/ EU018877/ EU018878/ EU018879/ EU018880/ EU018881/ EU018882/ EU018883/ EU018884/ EU018885/ EU018886/ EU018887/ EU018888/ EU018889/ EU018890/ EU018891/ EU018892/ EU018893/ EU018894/ EU018895/ EU018896/ EU018897/ EU018898/ EU018899/ EU018900/ EU018901/ EU018902/ EU018903/ EU018904/ EU018905/ EU018906/ EU018907/ EU018908/ EU018909/ EU018910/ EU018911/ EU018912/ EU018913/ EU018914/ EU018915/ EU018916/ EU018917/ EU018918/ EU018919/ EU018920/ EU018921/ EU018922/ EU018923/ EU018924/ EU018925/ EU018926/ EU018927/ EU018928/ EU018929/ EU018930/ EU018931/ EU018932/ EU018933/ EU018934/ EU018935/ EU018936/ EU018937/ EU018938/ EU018939/ EU018940/ EU018941/ EU018942/ EU018943/ EU018944/ EU018945/ EU018946/ EU018947/ EU018948/ EU018949/ EU018950/ EU018951/ EU018952/ EU018953/ EU018954/ EU018955/ EU018956/ EU018957/ EU018958/ EU018959/ EU018960/ EU018961/ EU018962/ EU018963/ EU018964/ EU018965/ EU018966/ EU018967/ EU018968/ EU018969/ EU018970/ EU018971/ EU018972/ EU018973/ EU018974/ EU018975/ EU018976/ EU018977/ EU018978/ EU018979/ EU018980/ EU018981/ EU018982/ EU018983/ EU018984/ EU018985/ EU018986/ EU018987/ EU018988/ EU018989/ EU018990/ EU018991/ EU018992/ EU018993/ EU018994/ EU018995/ EU018996/ EU018997/ EU018998/ EU018999/ EU019000/ EU019001/ EU019002/ EU019003/ EU019004/ EU019005/ EU019006/ EU019007/ EU019008/ EU019009/ EU019010/ EU019011/ EU019012/ EU019013/ EU019014/ EU019015/ EU019016/ EU019017/ EU019018/ EU019019/ EU019020/ EU019021/ EU019022/ EU019023/ EU019024/ EU019025/ EU019026/ EU019027/ EU019028/ EU019029/ EU019030/ EU019031/ EU019032/ EU019033/ EU019034/ EU019035/ EU019036/ EU019037/ EU019038/ EU019039/ EU019040/ EU019041/ EU019042/ EU019043/ EU019044/ EU019045/ EU019046/ EU019047/ EU019048/ EU019049/ EU019050/ EU019051/ EU019052/ EU019053/ EU019054/ EU019055/ EU019056/ EU019057/ EU019058/ EU019059/ EU019060/ EU019061/ EU019062/ EU019063/ EU019064/ EU019065/ EU019066/ EU019067/ EU019068/ EU019069/ EU019070/ EU019071/ EU019072/ EU019073/ EU019074/ EU019075/ EU019076/ EU019077/ EU019078/ EU019079/ EU019080
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2224419
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41. Ali MB, Chaminade F, Kanevsky I, Ennifar E, Josset L, Ficheux D, Darlix JL, Fossé P: Structural requirements for nucleocapsid protein-mediated dimerization of avian leukosis virus RNA. J Mol Biol; 2007 Sep 28;372(4):1082-96
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  • [Title] Structural requirements for nucleocapsid protein-mediated dimerization of avian leukosis virus RNA.
  • The avian leukosis virus (ALV) belongs to the alpha group of retroviruses that are widespread in nature.
  • To investigate the NCp12-mediated L3 dimerization reaction, we performed site-directed mutagenesis, gel retardation and heterodimerization assays and analysis of thermostability of dimeric RNAs.

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  • (PMID = 17706668.001).
  • [ISSN] 0022-2836
  • [Journal-full-title] Journal of molecular biology
  • [ISO-abbreviation] J. Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Nucleocapsid Proteins; 0 / RNA, Viral
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42. Pincetic A, Kuang Z, Seo EJ, Leis J: The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process. J Virol; 2010 May;84(9):4725-36
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  • The budding of avian sarcoma leukosis virus and HIV-1 Gag virus-like particles containing L-domain mutations can be rescued by fusion to ESCRT proteins, which cause entry into the budding pathway beyond these early steps.
  • We now demonstrate that the Vps4 protein does not associate with the avian sarcoma leukosis virus or the HIV-1 budding complexes when ISG15 is expressed.

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  • (PMID = 20164219.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R21 AI079025; United States / NIAID NIH HHS / AI / T32 AI060523; United States / NIAID NIH HHS / AI / AI079025
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CHMP5 protein, human; 0 / Cytokines; 0 / Endosomal Sorting Complexes Required for Transport; 0 / Ubiquitins; 0 / VTA1 protein, human; 60267-61-0 / ISG15 protein, human; 9008-11-1 / Interferons; EC 3.6.1.- / Adenosine Triphosphatases; EC 3.6.1.- / VPS4A protein, human; EC 3.6.1.- / Vacuolar Proton-Translocating ATPases
  • [Other-IDs] NLM/ PMC2863725
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43. Vasilakopoulou A, le Roux CW: Could a virus contribute to weight gain? Int J Obes (Lond); 2007 Sep;31(9):1350-6
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  • However, the rapid global spread of obesity resembles epidemiologically the spread of an infectious disease.
  • [MeSH-minor] Animals. Anthropometry. Aviadenovirus / pathogenicity. Avian Leukosis Virus / pathogenicity. Borna disease virus / pathogenicity. Distemper Virus, Canine / pathogenicity. Female. Humans. Male. PrPSc Proteins / pathogenicity. Weight Gain

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  • (PMID = 17420782.001).
  • [ISSN] 0307-0565
  • [Journal-full-title] International journal of obesity (2005)
  • [ISO-abbreviation] Int J Obes (Lond)
  • [Language] eng
  • [Grant] United Kingdom / Department of Health / / DHCS/05/05
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / PrPSc Proteins
  • [Number-of-references] 55
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44. Zavala G, Cheng S, Jackwood MW: Molecular epidemiology of avian leukosis virus subgroup J and evolutionary history of its 3' untranslated region. Avian Dis; 2007 Dec;51(4):942-53
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  • [Title] Molecular epidemiology of avian leukosis virus subgroup J and evolutionary history of its 3' untranslated region.
  • Avian leukosis subgroup J (ALV-J) causes a variety of tumors and mortality in meat-type chickens.
  • Overall, the unique region 3 was the least conserved within the 3' long terminal repeat (LTR), albeit the transcriptional regulatory elements typical of avian retroviruses (CAAT, CArG, PRE, TATA, and Y boxes) were highly conserved.
  • [MeSH-major] 3' Untranslated Regions / genetics. Avian Leukosis / epidemiology. Avian Leukosis Virus / genetics. Chickens. Poultry Diseases / epidemiology

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  • (PMID = 18251406.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 3' Untranslated Regions
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45. Espeseth DA, Lasher H: Early history of regulatory requirements for poultry biologics in the United States. Avian Dis; 2010 Dec;54(4):1136-43
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  • However, this began to change with the licensing of laryngotracheitis vaccine in 1933; pigeonpox vaccine in 1939; several Newcastle disease vaccines (inactivated in 1946, Roakin strain in 1948, B1 strain in 1950, and La Sota strain in 1952); and the first bronchitis vaccine in 1953.
  • The USDA's approach to the regulation of biologics in the early 1950s was still geared to the production of hog cholera products; however, as a result of the intervention of a group of dedicated poultry scientists, who were concerned about the poor performance of Newcastle disease vaccines, this soon changed.
  • The development and improvement of standards and regulatory requirements to address mycoplasma, leukosis, and other extraneous virus contaminations in chicken embryo origin products are reviewed.
  • The licensing of products to meet new and emerging disease problems in the poultry industry and the close interaction among research scientists, poultry industry, biologics manufacturers, and government regulatory officials that has been needed to ensure the availability of products that meet appropriate standards of purity, safety, potency, and efficacy are also addressed.

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  • (PMID = 21313831.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biological Products
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46. Zhang HM, Hunt HD, Kulkarni GB, Palmquist DE, Bacon LD: Lymphoid organ size varies among inbred lines 6(3) and 7(2) and their thirteen recombinant congenic strains of chickens with the same major histocompatibility complex. Poult Sci; 2006 May;85(5):844-53
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  • [Title] Lymphoid organ size varies among inbred lines 6(3) and 7(2) and their thirteen recombinant congenic strains of chickens with the same major histocompatibility complex.
  • The objective was to evaluate lymphoid organ size in chickens from a series of 13 recombinant congenic strains (RCS) and their highly inbred parental lines (6(3) and 7(2)).
  • The parental line 6(3) was selected for resistance to tumors induced by Marek's disease virus and avian leukosis viruses, whereas line 7(2) was selected for susceptibility to these tumors.
  • Previous studies have shown that lines 6(3) and 7(2) differ in the size of primary lymphoid organs; i.e., the bursa of Fabricius (BF) and the lobes of the thymus (T) are smaller in line 6(3) than line 7(2).
  • Males and females from 4 RCS and the 2 parental lines were evaluated a second time, and differences in the relative sizes in lymphoid organs among the RCS and parental lines were consistent.
  • The relative lymphoid organ size among the RCS appeared to cosegregate with the concentration of IgG in the plasma measured previously.

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  • (PMID = 16673761.001).
  • [ISSN] 0032-5791
  • [Journal-full-title] Poultry science
  • [ISO-abbreviation] Poult. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin G
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47. Hu J, Renaud G, Golmes T, Ferris A, Hendrie PC, Donahue RE, Hughes SH, Wolfsberg TG, Russell DW, Dunbar CE: Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors. Mol Ther; 2008 Sep;16(9):1617-1623
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  • [Title] Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors.
  • In this study, we report for the first time a systematic analysis of 198 avian sarcoma leukosis virus (ASLV) insertion sites identified in rhesus long-term repopulating cells, and a comparison of ASLV insertion patterns to Moloney murine leukemia virus (MLV) (n = 396) and simian immunodeficiency virus (SIV) (n = 289) using the newly released rhesus genome databank.

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  • [Copyright] Copyright © 2008 The American Society of Gene Therapy. Published by Elsevier Inc. All rights reserved.
  • (PMID = 28189014.001).
  • [ISSN] 1525-0024
  • [Journal-full-title] Molecular therapy : the journal of the American Society of Gene Therapy
  • [ISO-abbreviation] Mol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Elleder D, Stepanets V, Melder DC, Senigl F, Geryk J, Pajer P, Plachý J, Hejnar J, Svoboda J, Federspiel MJ: The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily. J Virol; 2005 Aug;79(16):10408-19
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  • [Title] The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily.
  • The five highly related envelope subgroups of the avian sarcoma and leukosis viruses (ASLVs), subgroup A [ASLV(A)] to ASLV(E), are thought to have evolved from an ancestral envelope glycoprotein yet utilize different cellular proteins as receptors.

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  • (PMID = 16051833.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI048682; United States / NIAID NIH HHS / AI / AI48682
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Codon, Terminator; 0 / Membrane Glycoproteins; 0 / Receptors, Virus; 0 / butyrophilin
  • [Other-IDs] NLM/ PMC1182627
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49. Sun S, Cui Z: Epidemiological and pathological studies of subgroup J avian leukosis virus infections in Chinese local "yellow" chickens. Avian Pathol; 2007 Jun;36(3):221-6
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  • [Title] Epidemiological and pathological studies of subgroup J avian leukosis virus infections in Chinese local "yellow" chickens.
  • Epidemiological, pathological and molecular studies indicate that subgroup J avian leukosis virus (ALV-J) infections are widely spread in "yellow chickens" of local breeds in China.
  • [MeSH-major] Avian Leukosis / epidemiology. Avian Leukosis Virus / classification. Chickens / virology. Poultry Diseases / epidemiology

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  • (PMID = 17497335.001).
  • [ISSN] 0307-9457
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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50. Lupiani B, Pandiri AR, Mays J, Hunt HD, Fadly AM: Molecular and biological characterization of a naturally occurring recombinant subgroup B avian leukosis virus with a subgroup J-like long terminal repeat. Avian Dis; 2006 Dec;50(4):572-8
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  • [Title] Molecular and biological characterization of a naturally occurring recombinant subgroup B avian leukosis virus with a subgroup J-like long terminal repeat.
  • Infection of broiler chickens with subgroup J avian leukosis virus (ALV) results in the induction of myeloid tumors.
  • We recently described the isolation of an ALV (AF115-4) from commercial egg-type chickens suffering from myeloid leukosis.
  • Inoculation of AF 115-4 into ALV-susceptible 1515 X 71 chickens resulted in the induction of lymphoid leukosis but not the expected myeloid leukosis affecting the commercial chickens.
  • [MeSH-major] Avian Leukosis Virus / genetics. Terminal Repeat Sequences / genetics. Viral Envelope Proteins / genetics
  • [MeSH-minor] Amino Acid Sequence. Animals. Avian Leukosis / virology. Base Sequence. Cell Line. Chickens / virology. Molecular Sequence Data. Poultry Diseases / virology

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  • (PMID = 17274296.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Envelope Proteins
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51. Pang P, Chen FY, Tang J, Ma LF, Wang JC, Zheng SJ: Avian leukosis virus p27 inhibits tumor necrosis factor alpha expression in RAW264.7 macrophages after stimulation with lipopolysaccharide. Acta Virol; 2010;54(2):119-24
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  • [Title] Avian leukosis virus p27 inhibits tumor necrosis factor alpha expression in RAW264.7 macrophages after stimulation with lipopolysaccharide.
  • Avian leukosis is a widely distributed disease caused by Avian leukosis virus (ALV).
  • ALV p27 is a capsid protein and group specific antigen, whose role in host immune response is poorly understood.
  • KEYWORDS: Avian leukosis virus; p27; tumor necrosis factor alpha; interleukins; macrophages; lipopolysaccharide.
  • [MeSH-major] Avian Leukosis Virus / immunology. Avian Leukosis Virus / pathogenicity. Macrophages / immunology. Macrophages / virology. Tumor Necrosis Factor-alpha / biosynthesis

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  • (PMID = 20545441.001).
  • [ISSN] 0001-723X
  • [Journal-full-title] Acta virologica
  • [ISO-abbreviation] Acta Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Antigens, Viral; 0 / Capsid Proteins; 0 / DNA, Viral; 0 / Interleukin-1beta; 0 / Interleukin-6; 0 / Lipopolysaccharides; 0 / Recombinant Fusion Proteins; 0 / Tumor Necrosis Factor-alpha; 147336-22-9 / Green Fluorescent Proteins; 187348-17-0 / Interleukin-12
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52. Fu SL, Huang YJ, Liang FP, Huang YF, Chuang CF, Wang SW, Yao JW: Malignant transformation of an epithelial cell by v-Src via tv-a-mediated retroviral infection: a new cell model for studying carcinogenesis. Biochem Biophys Res Commun; 2005 Dec 16;338(2):830-8
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  • To address both questions, we here established a non-transformed rat kidney epithelial RK3E cell line that constitutively expresses tv-a (receptor for subgroup A avian leukosis virus, ALV) for delivery of foreign genes via avian retroviral infection.
  • [MeSH-minor] Animals. Avian Proteins / genetics. Avian Proteins / metabolism. Cell Line, Tumor. Disease Models, Animal. Rats. Receptors, Virus / genetics. Receptors, Virus / metabolism. Retroviridae / genetics. Retroviridae / metabolism. Transfection / methods


53. Barbosa T, Ramirez M, Hafner S, Cheng S, Zavala G: Forensic investigation of a 1986 outbreak of osteopetrosis in commercial brown layers reveals a novel avian leukosis virus-related genome. Avian Dis; 2010 Sep;54(3):981-9
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  • [Title] Forensic investigation of a 1986 outbreak of osteopetrosis in commercial brown layers reveals a novel avian leukosis virus-related genome.
  • Avian leukosis virus (ALV) is known to cause several neoplastic conditions in chickens, such as B-cell lymphomas, myelocytomas, erythroblastosis, and other types of neoplasia including osteopetrosis.
  • The gp37 (transmembrane or TM) envelope protein showed three leucine to serine mutations that may represent important changes in the conformation of this protein, a finding that is currently being investigated.
  • [MeSH-major] Avian Leukosis Virus / genetics. Disease Outbreaks / veterinary. Osteopetrosis / veterinary. Poultry Diseases / virology

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  • (PMID = 20945777.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / Viral Proteins
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54. Li N, Xu B, Dong W, Qiao S, Lee LF, Zhang HM, Li M, Du N: Detection and localization of naturally transmitted avian leukosis subgroup J virus in egg-type chickens by in situ PCR hybridization. J Vet Med A Physiol Pathol Clin Med; 2007 Dec;54(10):553-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection and localization of naturally transmitted avian leukosis subgroup J virus in egg-type chickens by in situ PCR hybridization.
  • Avian leukosis virus (ALV) subgroup J (ALV-J) is an exogenous ALV and causes myeloid leukosis in meat-type chickens.
  • [MeSH-major] Avian Leukosis / transmission. Avian Leukosis / virology. Avian Leukosis Virus / isolation & purification. Poultry Diseases / virology

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  • (PMID = 18045338.001).
  • [ISSN] 0931-184X
  • [Journal-full-title] Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
  • [ISO-abbreviation] J Vet Med A Physiol Pathol Clin Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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55. Delos SE, La B, Gilmartin A, White JM: Studies of the "chain reversal regions" of the avian sarcoma/leukosis virus (ASLV) and ebolavirus fusion proteins: analogous residues are important, and a His residue unique to EnvA affects the pH dependence of ASLV entry. J Virol; 2010 Jun;84(11):5687-94
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  • [Title] Studies of the "chain reversal regions" of the avian sarcoma/leukosis virus (ASLV) and ebolavirus fusion proteins: analogous residues are important, and a His residue unique to EnvA affects the pH dependence of ASLV entry.
  • Here, we used mutagenesis and pseudovirus entry assays to test this model for the avian retrovirus avian sarcoma/leukosis virus (ASLV) and the filovirus ebolavirus Zaire.

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  • (PMID = 20335266.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI022470; United States / NIAID NIH HHS / AI / U54 AI057168; United States / NIAID NIH HHS / AI / R01 AI22470; United States / NIAID NIH HHS / AI / U54 AI57168
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Envelope Proteins; 0 / Viral Fusion Proteins; 4QD397987E / Histidine
  • [Other-IDs] NLM/ PMC2876614
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56. Simova-Curd SA, Huder JB, Boeni J, Robert N, Hatt JM: Investigations on the diagnosis and retroviral aetiology of renal neoplasia in budgerigars (Melopsittacus undulatus). Avian Pathol; 2010 Jun;39(3):161-7
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  • Investigations for virus identification included product-enhanced reverse transcriptase assay and enzyme-linked immunosorbent assay for the detection of avian leucosis virus group-specific antigen.
  • [MeSH-minor] Animals. Animals, Zoo / virology. Avian Leukosis / genetics. Avian Leukosis / radiography. Avian Leukosis / virology. Avian Leukosis Virus / isolation & purification. Diagnosis, Differential. Female. Genetic Predisposition to Disease. Lameness, Animal. Male. Melopsittacus. RNA-Directed DNA Polymerase / genetics. Reference Values. Reproducibility of Results. Switzerland

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  • (PMID = 20544420.001).
  • [ISSN] 1465-3338
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.7.49 / RNA-Directed DNA Polymerase
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57. Sun H, Qin M, Xiao Y, Yang F, Ni W, Liu S: Haemangiomas, leiomyosarcoma and myeloma caused by subgroup J avian leukosis virus in a commercial layer flock. Acta Vet Hung; 2010 Dec;58(4):441-51
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  • [Title] Haemangiomas, leiomyosarcoma and myeloma caused by subgroup J avian leukosis virus in a commercial layer flock.
  • In the diffusely swollen liver and spleen, multifocal or widespread marrow tumour cells filled with ball-like acidophilic particles in cytosol were observed, which are the characteristic pathological changes of avian myelocytomatosis.
  • The seroprevalence of avian leukosis subgroup J (ALV-J) antibodies was 13.46% (7/52), while ALV-A/B and reticuloendotheliosis virus (REV) antibodies were not detectable.
  • The DF-1 cells inoculated by virus extracted from liver samples from 24 infected chickens were cultured and the group-specific antigen (GSA) was identified by ELISA.
  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Disease Outbreaks / veterinary. Hemangioma / veterinary. Leiomyosarcoma / veterinary. Neoplasms, Plasma Cell / veterinary. Poultry Diseases / virology
  • [MeSH-minor] Animals. Avian Leukosis / epidemiology. Avian Leukosis / pathology. Avian Leukosis / virology. Chickens. China / epidemiology. Female

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  • (PMID = 21087914.001).
  • [ISSN] 0236-6290
  • [Journal-full-title] Acta veterinaria Hungarica
  • [ISO-abbreviation] Acta Vet. Hung.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Hungary
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58. Beniaminov AD, Samokhin AB, Ul'ianov NB, Miniat EE: [Characteristic of the two-step RNA dimerization in avian sarcoma and leukosis viruses]. Mol Biol (Mosk); 2005 Jan-Feb;39(1):147-54
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  • [Title] [Characteristic of the two-step RNA dimerization in avian sarcoma and leukosis viruses].
  • Similar model of two-step dimerization mechanism can be considered for avian sarcoma and leukosis virus group (ASLV) in spite of the absence of homology between dimer initiation site (DIS) of ASLV and that of HIV-1.
  • In this paper, short RNA fragments of two viruses: avian sarcoma virus CT-10 and avian leukosis virus HPRS-103 have been chosen in order to investigate the structural requirements of dimerization process and compare them to that of HIV-1.
  • Although both types of dimers were observed for both avian retroviruses chosen, fragments of CT-10 requires much higher RNA concentration to form loose dimer.
  • In spite of identical sequence of the loops (5'-A-CUGCAG-3') avian sarcoma virus CT-10 RNA fragments dimerization was greatly impaired.
  • The differences can be explained by deletion of adenine 271 in avian sarcoma virus CT-10 in the stem and by resulting shortening of the self-complementary loop.
  • [MeSH-major] Avian Leukosis Virus / genetics. Avian Sarcoma Viruses / genetics. Genome, Viral. RNA, Viral / genetics

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  • (PMID = 15773559.001).
  • [ISSN] 0026-8984
  • [Journal-full-title] Molekuliarnaia biologiia
  • [ISO-abbreviation] Mol. Biol. (Mosk.)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia
  • [Chemical-registry-number] 0 / RNA, Viral
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59. Bruce JW, Bradley KA, Ahlquist P, Young JA: Isolation of cell lines that show novel, murine leukemia virus-specific blocks to early steps of retroviral replication. J Virol; 2005 Oct;79(20):12969-78
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  • When engineered to express the TVA receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A), the five cell lines were resistant to infection with a MLV vector pseudotyped with the ASLV-A envelope protein but were fully susceptible to infection with an ASLV-A vector.

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  • (PMID = 16188999.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA70810; United States / NCI NIH HHS / CA / T32 CA009075; United States / NCI NIH HHS / CA / P01 CA022443; United States / NCI NIH HHS / CA / R01 CA070810; United States / NCI NIH HHS / CA / CA22443
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1235846
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60. Kalland KH, Ke XS, Øyan AM: Tumour virology--history, status and future challenges. APMIS; 2009 May;117(5-6):382-99
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  • The virus and host cell interactions have consequences at multiple levels, spanning from evolution through disease to models and tools for scientific discovery and treatment.
  • [MeSH-minor] Animals. Avian Leukosis / virology. Biological Evolution. Cell Transformation, Neoplastic. Chickens. DNA Tumor Viruses / genetics. DNA Tumor Viruses / pathogenicity. DNA Tumor Viruses / physiology. Epigenesis, Genetic. Gene Expression Regulation, Neoplastic. Gene Expression Regulation, Viral. Genes, Viral. Humans. Mammals / virology. Mice. Neoplasms / etiology. Neoplasms / virology. Oncogenes. RNA Interference. Research. Retroviridae / genetics. Retroviridae / physiology. Retroviridae Infections / physiopathology. Retroviridae Infections / virology

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  • (PMID = 19400863.001).
  • [ISSN] 1600-0463
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 165
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61. Kang Y, Moressi CJ, Scheetz TE, Xie L, Tran DT, Casavant TL, Ak P, Benham CJ, Davidson BL, McCray PB Jr: Integration site choice of a feline immunodeficiency virus vector. J Virol; 2006 Sep;80(17):8820-3
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  • FIV integration preferences are more similar to those of primate lentiviruses and distinct from those of Moloney murine leukemia virus, avian sarcoma leukosis virus, and foamy virus.

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  • (PMID = 16912328.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL079023; United States / NHLBI NIH HHS / HL / HL-51670; United States / NHLBI NIH HHS / HL / P01 HL051670; United States / NHLBI NIH HHS / HL / R01 HL075363; United States / NIGMS NIH HHS / GM / R01 GM068903; United States / NHLBI NIH HHS / HL / HL-75363; United States / NHLBI NIH HHS / HL / HL-79023
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proteins
  • [Other-IDs] NLM/ PMC1563849
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62. McNally MM, Wahlin KJ, Canto-Soler MV: Endogenous expression of ASLV viral proteins in specific pathogen free chicken embryos: relevance for the developmental biology research field. BMC Dev Biol; 2010 Oct 18;10:106
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  • BACKGROUND: The use of Specific Pathogen Free (SPF) eggs in combination with RCAS retrovirus, a member of the Avian Sarcoma-Leukosis Virus (ASLV) family, is of standard practice to study gene function and development.

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  • (PMID = 20955591.001).
  • [ISSN] 1471-213X
  • [Journal-full-title] BMC developmental biology
  • [ISO-abbreviation] BMC Dev. Biol.
  • [Language] ENG
  • [Grant] United States / NEI NIH HHS / EY / R01 EY004859; United States / NEI NIH HHS / EY / EY1765; United States / PHS HHS / / EYO4859
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Viral Proteins
  • [Other-IDs] NLM/ PMC2973938
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63. Santos VL, Williams SM, Zavala G, Barbosa T, Zhang J, Cheng S, Shivaprasad HL, Hafner S, Fadly A, Santos RL, Brown CC: Detection of reticuloendotheliosis virus by immunohistochemistry and in situ hybridization in experimentally infected Japanese quail embryos and archived formalin-fixed and paraffin-embedded tumours. Avian Pathol; 2008 Aug;37(4):451-6
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  • Histopathological changes in REV infection are not sufficient to differentiate it from avian lymphoid leukosis and Marek's disease, and currently there are no available in situ diagnostic methods for detection of active REV presence in pathologic specimens.
  • The in situ hybridization and immunohistochemistry assays proved to be efficient for the detection of several REV strains in Japanese quail embryos during active infection, whereas these assays were much less sensitive when applied to archived tissue samples from chronically infected birds with lymphoid tumours.
  • [MeSH-major] Coturnix / embryology. Immunohistochemistry / veterinary. In Situ Hybridization / veterinary. Neoplasms / veterinary. Reticuloendotheliosis Viruses, Avian / isolation & purification

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  • (PMID = 18622864.001).
  • [ISSN] 1465-3338
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 1HG84L3525 / Formaldehyde
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64. Takagi M, Ohashi K, Morimura T, Sugimoto C, Onuma M: The presence of the p53 transcripts with truncated open reading frames in Marek's disease tumor-derived cell lines. Leuk Res; 2006 Aug;30(8):987-92
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  • [Title] The presence of the p53 transcripts with truncated open reading frames in Marek's disease tumor-derived cell lines.
  • Several kinds of the p53 transcripts in which their open reading frames (ORFs) were truncated (ranging from 101 to 765 bp) were identified in Marek's disease (MD)-derived tumor cell lines as well as avian leukosis- and reticuloendotheliosis-derived ones, detected by nested RT-PCR and subsequent nucleotide sequence analysis.
  • [MeSH-major] Marek Disease / genetics. Open Reading Frames / genetics. Sequence Deletion. Transcription, Genetic / genetics. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 16448698.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
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65. Smith A, Benkel BF: A diagnostic assay for the endogenous ALV-type provirus ALVE-NSAC-3 of chickens. Anim Genet; 2008 Oct;39(5):574-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Avian Leukosis / diagnosis. Avian Leukosis Virus / genetics

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  • (PMID = 18644007.001).
  • [ISSN] 1365-2052
  • [Journal-full-title] Animal genetics
  • [ISO-abbreviation] Anim. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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66. Heidari M, Fitzgerald SD, Zhang HM, Silva RF, Lee LF, Dunn JR: Marek's disease virus-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles. Avian Dis; 2007 Sep;51(3):713-8
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  • [Title] Marek's disease virus-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles.
  • Marek's disease virus (MDV) is an oncogenic cell-associated herpesvirus that causes T-cell lymphoma in chickens.
  • Lymphoproliferative neoplasms in Marek's disease (MD) occur in various organs and tissues, including the viscera, peripheral nerves, skin, gonads, and musculatures.
  • [MeSH-major] Chickens / virology. Feathers. Marek Disease / pathology. Skin / pathology. Skin / virology. Skin Neoplasms / veterinary


67. Yang X, Lipchina I, Lifton M, Wang L, Sodroski J: Antibody binding in proximity to the receptor/glycoprotein complex leads to a basal level of virus neutralization. J Virol; 2007 Aug;81(16):8809-13
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  • Here, we demonstrate that retroviral infection mediated by the avian sarcoma-leukosis virus (ASLV-A) envelope glycoproteins can be neutralized by an antibody directed against a functionally unimportant component of a chimeric receptor protein.
  • This finding provides additional support for the hypothesis that steric hindrance is sufficient for antibody-mediated neutralization of retroviruses.

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  • (PMID = 17537847.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R37 AI024755; United States / NIAID NIH HHS / AI / U01 AI067854; United States / NIAID NIH HHS / AI / AI 073133; United States / NIAID NIH HHS / AI / R21 AI064009; United States / NIAID NIH HHS / AI / R01 AI039420; United States / NIAID NIH HHS / AI / AI 064009; United States / NIAID NIH HHS / AI / AI 39420; United States / NIAID NIH HHS / AI / P30 AI042848; United States / NIAID NIH HHS / AI / AI 42848; United States / NIAID NIH HHS / AI / U19 AI067854; United States / NIAID NIH HHS / AI / R01 AI040895; United States / NIAID NIH HHS / AI / AI 40895; United States / NIAID NIH HHS / AI / AI 24755; United States / NIAID NIH HHS / AI / R01 AI073133; United States / NIAID NIH HHS / AI / AI 67854
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Viral; 0 / CCR5 Receptor Antagonists; 0 / Glycoproteins; 0 / Ligands; 0 / Receptors, Virus; 0 / Viral Envelope Proteins
  • [Other-IDs] NLM/ PMC1951382
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68. Zhang HM, Bacon LD, Heidari M, Muir WM, Groenen MA, Zhang Y, Wong GK, Fulton JE, O'Sullivan NP, Albers GA, Vereijken AL, Rattink AP, Okimoto R, McKay JC, McLeod S, Cheng HH: Genetic variation at the tumour virus B locus in commercial and laboratory chicken populations assessed by a medium-throughput or a high-throughput assay. Avian Pathol; 2007 Aug;36(4):283-91
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  • The tumour virus B (TVB) locus encodes cellular receptors mediating infection by three subgroups of avian leukosis virus (B, D, and E).
  • All commercial pure lines examined in this study carry the TVB*S1 allele that sustains the susceptibility to avian leukosis viruses B, D, and E.
  • [MeSH-major] Avian Leukosis Virus / physiology. Chickens / genetics. Polymorphism, Single Nucleotide / genetics
  • [MeSH-minor] Alleles. Animals. Animals, Laboratory. Genetic Predisposition to Disease. Genotype. Oviposition / physiology. Polymerase Chain Reaction / veterinary. Poultry Diseases / genetics. Poultry Diseases / virology


69. Cheng Z, Liu J, Cui Z, Zhang L: Tumors associated with avian leukosis virus subgroup J in layer hens during 2007 to 2009 in China. J Vet Med Sci; 2010 Aug;72(8):1027-33
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  • [Title] Tumors associated with avian leukosis virus subgroup J in layer hens during 2007 to 2009 in China.
  • In the 3 years leading up to November 2009, 6 different types of naturally occurring neoplasms associated with avian leukosis virus subgroup J (ALV-J) were diagnosed by histopathology, polymerase chain reaction (PCR) and immunohistochemistry (IHC) in 140 layer hens out of approximately 100,000.
  • The most prevalent tumor type was hemangioma (50%) in commercial layer flocks; the second most prevalent neoplasm type was myelocytoma (38.6%); a small number of ALV-J positive lymphomas (4.3%) that were not associated with Marek's disease (MD) or lymphoid leukosis (LL) was observed.

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  • (PMID = 20467208.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / DNA Primers
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70. Hatai H, Ochiai K, Umemura T: Detection of Avian leukosis virus genome by a nested polymerase chain reaction using DNA and RNA from dried feather shafts. J Vet Diagn Invest; 2009 Jul;21(4):519-22
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  • [Title] Detection of Avian leukosis virus genome by a nested polymerase chain reaction using DNA and RNA from dried feather shafts.
  • The nested polymerase chain reaction (nPCR) using frozen feather pulp is useful for detecting fowl glioma-inducing virus (FGV), which belongs to the Avian leukosis virus family, and it has recently been suggested that FGV has spread to ornamental chickens kept in Japanese zoological gardens.
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / genetics. Avian Leukosis Virus / isolation & purification. Chickens. Feathers / virology. Polymerase Chain Reaction / veterinary

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  • (PMID = 19564502.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / RNA, Viral
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71. Reinisová M, Senigl F, Yin X, Plachy J, Geryk J, Elleder D, Svoboda J, Federspiel MJ, Hejnar J: A single-amino-acid substitution in the TvbS1 receptor results in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroups B and D and resistance to infection by subgroup E in vitro and in vivo. J Virol; 2008 Mar;82(5):2097-105
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  • [Title] A single-amino-acid substitution in the TvbS1 receptor results in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroups B and D and resistance to infection by subgroup E in vitro and in vivo.
  • The avian sarcoma and leukosis virus (ASLV) family of retroviruses contains five highly related envelope subgroups (A to E) thought to have evolved from a common viral ancestor in the chicken population.
  • Here, we show that the C125S substitution in Tvb(S1) significantly reduces the susceptibility of line M cells to infection by ASLV(B) and ASLV(D) and virtually eliminates susceptibility to ASLV(E) infection both in cultured cells and in the incidence and growth of avian sarcoma virus-induced sarcomas in chickens.

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  • (PMID = 18094190.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI048682; United States / NIAID NIH HHS / AI / AI48682
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Receptors, Virus
  • [Other-IDs] NLM/ PMC2258910
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72. Zavala G, Cheng S: Experimental infection with avian leukosis virus isolated from Marek's disease vaccines. Avian Dis; 2006 Jun;50(2):232-7
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  • [Title] Experimental infection with avian leukosis virus isolated from Marek's disease vaccines.
  • Recently, avian leukosis virus (ALV) was isolated from four lots of Marek's disease vaccine produced by two laboratories.
  • [MeSH-major] Avian Leukosis / transmission. Avian Leukosis Virus / isolation & purification. Chickens / virology. Drug Contamination. Marek Disease / prevention & control. Poultry Diseases / virology. Viral Vaccines / immunology
  • [MeSH-minor] Animals. Antibodies, Viral. Chick Embryo. Female. Infectious Disease Transmission, Vertical / veterinary. Viremia

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  • (PMID = 16863073.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / Viral Vaccines
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73. Du Z, Podsypanina K, Huang S, McGrath A, Toneff MJ, Bogoslovskaia E, Zhang X, Moraes RC, Fluck M, Allred DC, Lewis MT, Varmus HE, Li Y: Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models. Proc Natl Acad Sci U S A; 2006 Nov 14;103(46):17396-401
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  • [Title] Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models.
  • We have adapted the avian leukosis virus RCAS (replication-competent avian sarcoma-leukosis virus LTR splice acceptor)-mediated somatic gene transfer technique to introduce oncogenes into mammary cells in mice transgenic for the avian subgroup A receptor gene, tva, under control of the mouse mammary tumor virus (MMTV) promoter.

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  • (PMID = 17090666.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01 CA084243-07; United States / NCI NIH HHS / CA / R01 CA113869; United States / NCI NIH HHS / CA / P01 CA94060-02; United States / NCI NIH HHS / CA / U01 CA084243; United States / NCI NIH HHS / CA / P50 CA058183; United States / NCI NIH HHS / CA / P01 CA094060
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Polyomavirus Transforming; 0 / Myc protein, mouse; 0 / Proto-Oncogene Proteins c-myc; 136601-57-5 / Cyclin D1
  • [Other-IDs] NLM/ PMC1635021
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74. Hafner S, Williams SM, Sutton MT: Retroviral inclusions in the enteric smooth muscle of a tumor-bearing young chicken. Avian Dis; 2007 Mar;51(1):133-6
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  • Ultrastructurally, inclusion bodies in enteric smooth muscle were viral matrix inclusions, and virions resembling avian retroviruses were present in adjacent intercellular spaces.
  • Polymerase chain reaction (PCR) of the deoxyribonucleic acid (DNA) extracted from tumor tissues indicated the presence of proviral DNA of subgroup J avian leukosis virus.
  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Intestinal Neoplasms / veterinary. Muscle, Smooth / virology. Poultry Diseases / virology

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  • (PMID = 17461280.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral
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75. Van Hoeven NS, Miller AD: Use of different but overlapping determinants in a retrovirus receptor accounts for non-reciprocal interference between xenotropic and polytropic murine leukemia viruses. Retrovirology; 2005 Dec 15;2:76
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  • Three groups of viruses demonstrate a non-reciprocal pattern of interference (NRI), which requires the existence of both a common receptor utilized by all viruses within the group, and a specific receptor that is used by a subset of viruses.
  • In the case of avian sarcoma and leukosis virus types B, D, and E, the two receptors are distinct protein products of a single gene.

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  • (PMID = 16354307.001).
  • [ISSN] 1742-4690
  • [Journal-full-title] Retrovirology
  • [ISO-abbreviation] Retrovirology
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK047754; United States / NHLBI NIH HHS / HL / HL36444; United States / NHLBI NIH HHS / HL / P01 HL036444; United States / NHLBI NIH HHS / HL / HL54881; United States / NIDDK NIH HHS / DK / DK47754; United States / NHLBI NIH HHS / HL / P50 HL054881
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Gene Products, env; 0 / Receptors, G-Protein-Coupled; 0 / Receptors, Virus; 0 / Recombinant Fusion Proteins; 0 / xenotropic and polytropic retrovirus receptor
  • [Other-IDs] NLM/ PMC1325250
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76. Fossum O, Jansson DS, Etterlin PE, Vågsholm I: Causes of mortality in laying hens in different housing systems in 2001 to 2004. Acta Vet Scand; 2009;51:3
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  • Using the number of disease outbreaks in caged flocks as the baseline, the expected number of flocks with a certain category of disease in the other housing systems was estimated having regard to the total number of birds in the population.
  • RESULTS: Common causes of mortality in necropsied laying hens included colibacillosis, erysipelas, coccidiosis, red mite infestation, lymphoid leukosis and cannibalism.
  • Less common diagnoses were Newcastle Disease, pasteurellosis and botulism.
  • Future research should focus on finding suitable prophylactic measures, including efficient biosecurity routines, to reduce the risk of infectious diseases and cannibalism in litter-based housing systems for laying hens.

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  • (PMID = 19146656.001).
  • [ISSN] 1751-0147
  • [Journal-full-title] Acta veterinaria Scandinavica
  • [ISO-abbreviation] Acta Vet. Scand.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2652464
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77. Hatai H, Ochiai K, Murakami M, Imanishi S, Tomioka Y, Toyoda T, Ohashi K, Umemura T: Prevalence of fowl glioma-inducing virus in chickens of zoological gardens in Japan and nucleotide variation in the env gene. J Vet Med Sci; 2008 May;70(5):469-74
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  • Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis virus (ALV), is tumorigenic in the nervous system.
  • In this study, the prevalence of the disease was examined in a total of 129 chickens in three other zoological gardens by nested polymerase chain reaction (PCR), reverse transcription nested PCR and enzyme-linked immunosorbent assay.

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  • (PMID = 18525168.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Gene Products, env
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78. Takagi M, Takeda T, Asada Y, Sugimoto C, Onuma M, Ohashi K: The presence of a short form of p53 in chicken lymphoblastoid cell lines during apoptosis. J Vet Med Sci; 2006 Jun;68(6):561-6
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  • To examine the roles of a short form of p53 in the regulation of apoptosis in chicken lymphoblastoid tumor cell lines derived from Marek's disease (MD) and avian leukosis (AL), the expressions of the p53 proteins were analyzed in these cell lines in which apoptosis was chemically induced.

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  • (PMID = 16820712.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
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79. Chang KW, Barsov EV, Ferris AL, Hughes SH: Mutations of a residue within the polyproline-rich region of Env alter the replication rate and level of cytopathic effects in chimeric avian retroviral vectors. J Virol; 2005 Aug;79(16):10258-67
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  • [Title] Mutations of a residue within the polyproline-rich region of Env alter the replication rate and level of cytopathic effects in chimeric avian retroviral vectors.
  • Previous attempts to extend the host range of the avian sarcoma/leukosis virus (ASLV)-based RCASBP vectors produced two viral vectors, RCASBP M2C (4070A) and RCASBP M2C (797-8), which replicate using the amphotropic murine leukemia virus 4070A Env protein (2).
  • Both viruses were adapted to replicate efficiently in the avian cell line DF-1, but RCASBP M2C (4070A) caused extensive cytopathic effects (CPE) in DF-1 cells whereas RCASBP M2C (797-8) induced low levels of CPE.
  • [MeSH-major] Cytopathogenic Effect, Viral. Gene Products, env / chemistry. Orthoreovirus, Avian / physiology. Virus Replication

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  • (PMID = 16051819.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / Gene Products, env; 0 / Peptides; 25191-13-3 / polyproline; F64QU97QCR / Dantrolene; SY7Q814VUP / Calcium
  • [Other-IDs] NLM/ PMC1182669
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80. Zhang X, Liao M, Jiao P, Luo K, Zhang H, Ren T, Zhang G, Xu C, Xin C, Cao W: Development of a loop-mediated isothermal amplification assay for rapid detection of subgroup J avian leukosis virus. J Clin Microbiol; 2010 Jun;48(6):2116-21
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  • [Title] Development of a loop-mediated isothermal amplification assay for rapid detection of subgroup J avian leukosis virus.
  • Infection of breeder flocks in China with subgroup J avian leukosis virus (ALV-J) has increased recently.
  • A ladder pattern on gel electrophoresis was observed for ALV-J isolates but not for other viruses.
  • [MeSH-major] Avian Leukosis / diagnosis. Avian Leukosis Virus / isolation & purification. Nucleic Acid Amplification Techniques / methods. Poultry Diseases / diagnosis. Virology / methods

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  • (PMID = 20375232.001).
  • [ISSN] 1098-660X
  • [Journal-full-title] Journal of clinical microbiology
  • [ISO-abbreviation] J. Clin. Microbiol.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2884476
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81. Robinson JP, VanBrocklin MW, Guilbeault AR, Signorelli DL, Brandner S, Holmen SL: Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene; 2010 Jan 21;29(3):335-44
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  • We evaluated the effect of activated BRAF in glioma formation using the retroviral replication-competent avian leukosis virus long terminal repeat, splice acceptor (RCAS)/TVA system to transfer genes encoding activated forms of BRAF, KRas, Akt and Cre to nestin-expressing neural progenitor cells in Ink4a/Arf(lox/lox) mice in vivo.


82. Kim YJ, Park SI, Park SJ, Kim HH, Jung YW, Kwon JT, Jang BG, Kim HK, Cho KO: Molecular analysis of endogenous avian leukosis/sarcoma virus genomes in Korean chicken embryos. J Vet Med Sci; 2008 Jan;70(1):17-23
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  • [Title] Molecular analysis of endogenous avian leukosis/sarcoma virus genomes in Korean chicken embryos.
  • Since the status of endogenous avian leucosis/sarcoma virus (ALSV) infections in Korean broiler chickens is unclear, this study examined embryonated eggs obtained from broiler farms and Korean native chicken breeds in Korea using PCR with the primer sets specific for endogenous ALSvs. The PCR assays detected the genomes of EAV, ev, ev/J and ART-CH belonging to the endogenous ALSV from all embryos tested.

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  • (PMID = 18250567.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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83. Wu X, Qian K, Qin A, Shen H, Wang P, Jin W, Eltahir YM: Recombinant avian leukosis viruses of subgroup J isolated from field infected commercial layer chickens with hemangioma and myeloid leukosis possess an insertion in the E element. Vet Res Commun; 2010 Oct;34(7):619-32
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  • [Title] Recombinant avian leukosis viruses of subgroup J isolated from field infected commercial layer chickens with hemangioma and myeloid leukosis possess an insertion in the E element.
  • BACKGROUND: Five isolates (JS09GY2, JS09GY3, JS09GY4, JS09GY5, and JS09GY6) of avian leukosis virus subgroup J (ALV-J) were isolated from six infected commercial layer flocks displaying both hemangioma and myeloid leukosis (ML), which shared the same parental line, in China in 2009.
  • By full genome sequences analysis, a 19-nucleotide repeat sequence was identified in the primer binding site (PBS)-leader region of isolates JS09GY3 and JS09GY6, located between sites 249 and 250 according to the sequence of reference strain HPRS103, and also present in Rous sarcoma virus strain Schmidt-Ruppin B (RSV-SRB), Rous associated virus type 1 (RAV-1), and Rous associated virus type 2 (RAV-2).
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / classification. Avian Leukosis Virus / genetics. Chickens. Hemangioma / veterinary

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  • (PMID = 20676760.001).
  • [ISSN] 1573-7446
  • [Journal-full-title] Veterinary research communications
  • [ISO-abbreviation] Vet. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA Transposable Elements
  • [Other-IDs] NLM/ PMC2931761
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84. Diaz-Griffero F, Jackson AP, Brojatsch J: Cellular uptake of avian leukosis virus subgroup B is mediated by clathrin. Virology; 2005 Jun 20;337(1):45-54
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  • [Title] Cellular uptake of avian leukosis virus subgroup B is mediated by clathrin.
  • Avian leukosis virus (ALV) requires endocytosis and a low pH step for successful viral entry.
  • [MeSH-major] Avian Leukosis Virus / physiology. Clathrin / physiology. Endocytosis. Fibroblasts / virology

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  • (PMID = 15914219.001).
  • [ISSN] 0042-6822
  • [Journal-full-title] Virology
  • [ISO-abbreviation] Virology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Clathrin
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85. Silva RF, Fadly AM, Taylor SP: Development of a polymerase chain reaction to differentiate avian leukosis virus (ALV) subgroups: detection of an ALV contaminant in commercial Marek's disease vaccines. Avian Dis; 2007 Sep;51(3):663-7
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  • [Title] Development of a polymerase chain reaction to differentiate avian leukosis virus (ALV) subgroups: detection of an ALV contaminant in commercial Marek's disease vaccines.
  • Avian leukosis viruses (ALVs) are common in many poultry flocks and can be detected using an enzyme-linked immunosorbent assay or any other test designed to identify p27, the group-specific antigen located in gag.
  • To demonstrate the usefulness of these primers, we obtained from the Center for Veterinary Biologics in Iowa culture supernatant from chicken embryo fibroblasts infected with an ALV that was found to be a contaminant in two commercial Marek's disease vaccines.
  • [MeSH-major] Avian Leukosis Virus / isolation & purification. Chickens / virology. Drug Contamination. Marek Disease / prevention & control. Polymerase Chain Reaction / veterinary. Viral Vaccines / standards

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  • (PMID = 17992923.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Viral Vaccines
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86. Ka S, Kerje S, Bornold L, Liljegren U, Siegel PB, Andersson L, Hallböök F: Proviral integrations and expression of endogenous avian leucosis virus during long term selection for high and low body weight in two chicken lines. Retrovirology; 2009;6:68
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  • [Title] Proviral integrations and expression of endogenous avian leucosis virus during long term selection for high and low body weight in two chicken lines.
  • The main differentially expressed transcripts were endogenous retroviral sequences identified as avian leucosis virus subgroup-E (ALVE).
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / physiology. Body Weight. Chickens / growth & development. Gene Expression Regulation, Viral. Proviruses / physiology. Virus Integration

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  • [ISSN] 1742-4690
  • [Journal-full-title] Retrovirology
  • [ISO-abbreviation] Retrovirology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
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  • [Other-IDs] NLM/ PMC2717048
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87. Nakamura K, Ito M, Fujino K, Yamamoto Y, Mase M, Yamada M, Kobayashi H, Harada T: Pathology and microbiology of dermal squamous cell carcinoma in young brown chickens reared on reused litter. Avian Dis; 2010 Sep;54(3):1120-4
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  • Avian leukosis virus antigens could not be found in the neoplastic squamous cells in the dermis.
  • Virologically, reverse transcription-polymerase chain reactions of the skin with DSCC for fowlpox virus and avian leukosis virus were negative.

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  • (PMID = 20945801.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Derse D, Crise B, Li Y, Princler G, Lum N, Stewart C, McGrath CF, Hughes SH, Munroe DJ, Wu X: Human T-cell leukemia virus type 1 integration target sites in the human genome: comparison with those of other retroviruses. J Virol; 2007 Jun;81(12):6731-41
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  • On the other hand, integration of avian sarcoma-leukosis virus (ASLV) shows little preference either for genes, transcription start sites, or CpG islands.

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  • (PMID = 17409138.001).
  • [ISSN] 0022-538X
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / N01CO12400; United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1900082
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89. Mays JK, Bacon LD, Pandiri AR, Fadly AM: Response of white leghorn chickens of various B haplotypes to infection at hatch with subgroup J avian leukosis virus. Avian Dis; 2005 Jun;49(2):214-9
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  • [Title] Response of white leghorn chickens of various B haplotypes to infection at hatch with subgroup J avian leukosis virus.
  • White leghorn chickens from seven 15.B congenic lines (genetically similar except for genes linked to the major histocompatibility complex [MHC] B haplotype) and two Line 0.B semicongenic lines were infected at hatch with strain ADOL Hc-1 of subgroup J avian leukosis virus (ALV-J).
  • [MeSH-major] Avian Leukosis / genetics. Avian Leukosis Virus / isolation & purification. Chickens / genetics. Poultry Diseases / virology

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  • (PMID = 16094825.001).
  • [ISSN] 0005-2086
  • [Journal-full-title] Avian diseases
  • [ISO-abbreviation] Avian Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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90. Průková D, Vernerová Z, Pilcík T, Stepanets V, Indrová M, Geryk J, Plachý J, Hejnar J, Svoboda J: Differences in pathogenicity among strains of the same or different avian leukosis virus subgroups. Avian Pathol; 2007 Feb;36(1):15-27
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  • [Title] Differences in pathogenicity among strains of the same or different avian leukosis virus subgroups.
  • An efficient induction of wasting disease in chickens by avian leukosis virus (ALV), particularly ALV subgroup C, requires >102 infectious units virus inoculated in mid embryogenesis.
  • The most conspicuous symptoms of the disease were induced by ALV subgroup C; however, significant differences in the occurrence of wasting disease were found among individual members of this subgroup.
  • In agreement with this finding was a failure of chickens to respond to Brucella antigen and an inability of their splenocytes to respond to Concanavalin A, both of which pointed to the damage of immune reactivity.
  • [MeSH-major] Avian Leukosis / virology. Avian Leukosis Virus / classification. Avian Leukosis Virus / pathogenicity. Chickens / virology. Poultry Diseases / virology

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  • (PMID = 17364506.001).
  • [ISSN] 0307-9457
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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91. Chen M, Granger AJ, Vanbrocklin MW, Payne WS, Hunt H, Zhang H, Dodgson JB, Holmen SL: Inhibition of avian leukosis virus replication by vector-based RNA interference. Virology; 2007 Sep 1;365(2):464-72
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  • [Title] Inhibition of avian leukosis virus replication by vector-based RNA interference.
  • In this study, replication competent retroviral vectors were designed to deliver shRNA-mirs targeting subgroup B avian leukosis virus (ALV), the most effective of which reduced expression of protein targets by as much as 90% in cultured avian cells.
  • This study demonstrates efficient antiviral RNAi in avian cells using shRNA-mirs expressed from pol II promoters, including an inducible promoter, allowing for the regulation of the antiviral effect by doxycycline.
  • [MeSH-major] Avian Leukosis Virus / genetics. RNA Interference. Virus Replication / genetics