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1. Barabouti DG, Wong WD: Current management of rectal cancer: total mesorectal excision (nerve sparing) technique and clinical outcome. Surg Oncol Clin N Am; 2005 Apr;14(2):137-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Digestive System Surgical Procedures / methods. Rectal Neoplasms / surgery
  • [MeSH-minor] Anal Canal / physiopathology. Anal Canal / radiation effects. Autonomic Nervous System / anatomy & histology. Autonomic Nervous System / radiation effects. Combined Modality Therapy. Dissection. Female. Humans. Laparoscopy. Neoplasm Recurrence, Local / epidemiology. Pelvis / innervation. Recovery of Function. Rectum / anatomy & histology

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  • (PMID = 15817232.001).
  • [ISSN] 1055-3207
  • [Journal-full-title] Surgical oncology clinics of North America
  • [ISO-abbreviation] Surg. Oncol. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 72
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2. Schaller B, Sandu N, Filis A, Ottaviani G, Rasper J, Nöethen C, Buchfelder M, Trigemino-Cardiac-Reflex-Examination-Group (T.C.R.E.G.): Trigemino-cardiac reflex: the trigeminal depressor responses during skull base surgery. Clin Neurol Neurosurg; 2009 Feb;111(2):220
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Autonomic Nervous System Diseases / physiopathology. Autonomic Nervous System Diseases / therapy. Bradycardia / physiopathology. Bradycardia / therapy. Electrocardiography / methods. Humans. Monitoring, Intraoperative / methods. Reflex, Abnormal / physiology. Skull Base Neoplasms / surgery

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  • [CommentOn] Clin Neurol Neurosurg. 2008 Jul;110(7):662-6 [18514393.001]
  • [CommentOn] Clin Neurol Neurosurg. 2008 Apr;110(4):321-7 [18329164.001]
  • (PMID = 18996640.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Netherlands
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3. Mattes D, Mayer M, Feichtinger M, Lindner S: Neurological picture. A case of Pourfour du Petit syndrome following tumour surgery of the mandible. J Neurol Neurosurg Psychiatry; 2009 Jan;80(1):69
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Anisocoria / etiology. Autonomic Nervous System Diseases / complications. Fibroma / surgery. Mandibular Neoplasms / surgery. Mydriasis / etiology

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  • (PMID = 19091709.001).
  • [ISSN] 1468-330X
  • [Journal-full-title] Journal of neurology, neurosurgery, and psychiatry
  • [ISO-abbreviation] J. Neurol. Neurosurg. Psychiatry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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4. Eisenhofer G, Sharabi Y, Pacak K: Unexplained symptomatic paroxysmal hypertension in pseudopheochromocytoma: a stress response disorder? Ann N Y Acad Sci; 2008 Dec;1148:469-78
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among overall numbers of patients tested for pheochromocytoma, less than 2% harbor the tumor.
  • Similar to patients with the real tumor, patients with pseudopheochromocytoma can be misdiagnosed with panic disorder.
  • Because the clinical manifestations of pseudopheochromocytoma are similar, if not identical, to those due to excess circulating catecholamines in patients with the tumor, the most attractive explanation for the disorder is that it involves altered function of the autonomic nervous system.
  • [MeSH-minor] Adrenal Gland Neoplasms / physiopathology. Adrenal Gland Neoplasms / therapy. Diagnosis, Differential. Epinephrine / metabolism. Humans. Panic Disorder / physiopathology


5. Yale SH, Vasudeva S, Mazza JJ, Rolak L, Arrowood J, Stichert S, Stratman ES: Disorders of flushing. Compr Ther; 2005;31(1):59-71
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  • Accurate diagnosis requires a thorough history and physical examination emphasizing the age of the patient, temporal association of flushing with occupation, environmental, stress, food, or drug exposure, and the duration of the episode.
  • [MeSH-major] Flushing / diagnosis. Flushing / etiology
  • [MeSH-minor] Alcohol Drinking / adverse effects. Autonomic Nervous System Diseases / complications. Diagnosis, Differential. Drug-Related Side Effects and Adverse Reactions. Humans. Marine Toxins / poisoning. Neoplasms / complications. Occupational Exposure / adverse effects. Postmenopause. Rosacea / complications. Syndrome

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  • (PMID = 15793325.001).
  • [ISSN] 0098-8243
  • [Journal-full-title] Comprehensive therapy
  • [ISO-abbreviation] Compr Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Marine Toxins
  • [Number-of-references] 135
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6. Warman M, Herskovitz P, Halperin D: Radiology quiz case. Cervical sympathetic schwannoma. Arch Otolaryngol Head Neck Surg; 2008 Jul;134(7):781-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Autonomic Nervous System Diseases / diagnosis. Head and Neck Neoplasms / diagnosis. Magnetic Resonance Angiography. Magnetic Resonance Imaging. Neurilemmoma / diagnosis. Peripheral Nervous System Neoplasms / diagnosis. Pharyngeal Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Carotid Arteries / pathology. Carotid Stenosis / diagnosis. Carotid Stenosis / pathology. Carotid Stenosis / surgery. Humans. Male. Neck / pathology. Neck / surgery


7. Zhang C, Li GX, Ding ZH, Wu T, Zhong SZ: [Preservation of the autonomic nerve in rectal cancer surgery: anatomical factors in ligation of the inferior mesenteric artery]. Nan Fang Yi Ke Da Xue Xue Bao; 2006 Jan;26(1):49-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Preservation of the autonomic nerve in rectal cancer surgery: anatomical factors in ligation of the inferior mesenteric artery].
  • OBJECTIVE: To evaluate the regional anatomy between the abdominal autonomic nerves including the abdominal aortic plexus (AAP) and the inferior mesenteric artery (IMA), and explore the safe ligation point on the IMA and the optimal dissection method to avoid autonomic nerve injuries.
  • No autonomic nerves were found in the area around the root of the IMA, and the point where the IMA and the left trunk of the AAP intersected was highly variable.
  • CONCLUSIONS: In view of autonomic nerve preservation, the only safe site for ligation of the IMA is at its origin, and no other such sites are available along the IMA trunk and its branches.
  • The IMA and the posterior fascia layer containing the autonomic nerves constitute the optimal surgical plane for IMA ligation, which should be performed following skeletonization of the IMA with careful preservation of the integrity of the posterior fascia layer.
  • [MeSH-major] Autonomic Pathways / anatomy & histology. Mesenteric Artery, Inferior / surgery. Rectal Neoplasms / surgery. Rectum / surgery. Trauma, Nervous System / prevention & control

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  • (PMID = 16495175.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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8. Sangster G, Do D, Previgliano C, Li B, LaFrance D, Heldmann M: Primary retroperitoneal paraganglioma simulating a pancreatic mass: a case report and review of the literature. HPB Surg; 2010;2010:645728
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  • Paragangliomas are extra-adrenal tumors of the autonomic nervous system and may be found within the skull base, neck, chest, and abdomen.
  • When presenting within the abdominal cavity, they may arise as a primary retroperitoneal neoplasm and can mimic vascular malformations or other conditions related to specific retroperitoneal organs such as the pancreas, kidneys, or adrenals.
  • [MeSH-major] Pancreatic Neoplasms / diagnosis. Paraganglioma / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Abdominal Pain / etiology. Biopsy, Fine-Needle. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / surgery. Diagnosis, Differential. Frozen Sections. Humans. Immunohistochemistry. Kidney Neoplasms / diagnosis. Kidney Neoplasms / surgery. Male. Middle Aged. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / surgery. Positron-Emission Tomography. Rare Diseases. Tomography, X-Ray Computed

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  • (PMID = 21188160.001).
  • [ISSN] 1607-8462
  • [Journal-full-title] HPB surgery : a world journal of hepatic, pancreatic and biliary surgery
  • [ISO-abbreviation] HPB Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3004405
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9. Politi M, Toro C, Cian R, Costa F, Robiony M: Horner's syndrome due to a large schwannoma of the cervical sympathetic chain: report of case. J Oral Maxillofac Surg; 2005 May;63(5):707-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Autonomic Nervous System Diseases / complications. Head and Neck Neoplasms / complications. Horner Syndrome / etiology. Neurilemmoma / complications


10. Huy PT, Sauvaget E: Unilateral rhinorrhea after translabyrinthine surgery due to parasympathetic hypersensitive syndrome: differentiation from cerebrospinal fluid leakage. Otol Neurotol; 2010 Sep;31(7):1160-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The pathophysiogenetic mechanism suggests a neuroplastic phenomenon involving a denervation hypersensitivity reaction of the autonomous system.
  • [MeSH-major] Autonomic Nervous System Diseases / diagnosis. Cerebrospinal Fluid Rhinorrhea / diagnosis. Ear, Inner / surgery. Postoperative Complications / diagnosis
  • [MeSH-minor] Administration, Intranasal. Adult. Anastomosis, Surgical. Cholinergic Antagonists / administration & dosage. Cholinergic Antagonists / therapeutic use. Cranial Nerve Neoplasms / surgery. Diagnosis, Differential. Facial Nerve / surgery. Facial Nerve Diseases / surgery. Humans. Hypoglossal Nerve / surgery. Male. Middle Aged. Neurilemmoma / surgery. Neuroma, Acoustic / surgery

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  • (PMID = 20657327.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cholinergic Antagonists
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11. Guran T, Turan S, Bereket A, Akcay T, Unluguzel G, Bas F, Gunoz H, Saka N, Bundak R, Darendeliler F, Isguven P, Yildiz M, Adal E, Sarikaya S, Baygin LA, Memioglu N, Onal H, Ercan O, Haklar G: The role of leptin, soluble leptin receptor, resistin, and insulin secretory dynamics in the pathogenesis of hypothalamic obesity in children. Eur J Pediatr; 2009 Sep;168(9):1043-8
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  • MATERIALS AND METHODS: Children who had hypothalamo-pituitary tumor were divided into two groups.
  • CONCLUSION: Hypothalamic obesity seems to be related to both dysregulated afferent (leptin) and efferent (insulin) neural outputs through the autonomic nervous system resulting in energy storage as fat.
  • [MeSH-minor] Adolescent. Astrocytoma / metabolism. Astrocytoma / pathology. Astrocytoma / physiopathology. Body Mass Index. Child. Craniopharyngioma / metabolism. Craniopharyngioma / pathology. Craniopharyngioma / physiopathology. Dysgerminoma / metabolism. Dysgerminoma / pathology. Dysgerminoma / physiopathology. Female. Glucose Tolerance Test. Glycemic Index. Homeostasis / physiology. Humans. Hypothalamic Neoplasms / metabolism. Hypothalamic Neoplasms / pathology. Hypothalamic Neoplasms / physiopathology. Male

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  • (PMID = 19043735.001).
  • [ISSN] 1432-1076
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Insulin; 0 / Leptin; 0 / RETN protein, human; 0 / Receptors, Leptin; 0 / Resistin; 0 / leptin receptor, human
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12. Eskelinen M, Ollonen P: Life stress and losses and deficit in adulthood as breast cancer risk factor: a prospective case-control study in Kuopio, Finland. In Vivo; 2010 Nov-Dec;24(6):899-904
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  • CONCLUSION: the results of this study support a weak association between life stress and losses in adulthood and breast cancer risk and it might be that stress and losses impacts indirectly on breast cancer risk, affecting behaviour, or directly on the hypothalamic-pituitary-adrenal axis and autonomic nervous system functioning.
  • [MeSH-major] Breast Neoplasms / epidemiology. Stress, Psychological / complications

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  • (PMID = 21164052.001).
  • [ISSN] 1791-7549
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
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13. Kamal A, Abd El-Fattah AM, Tawfik A, Abdel Razek AA: Cervical sympathetic schwannoma with postoperative first bite syndrome. Eur Arch Otorhinolaryngol; 2007 Sep;264(9):1109-11
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  • Extracranial schwannomas occurring in the head and neck region may arise from cranial, peripheral or autonomic nerves.
  • [MeSH-major] Ganglia, Sympathetic / pathology. Neurilemmoma / pathology. Peripheral Nervous System Neoplasms / pathology. Peripheral Nervous System Neoplasms / surgery

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  • (PMID = 17431654.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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14. Lucini D, Cannone V, Malacarne M, Bruno D, Beltrami S, Pizzinelli P, Piazza E, Di Fede G, Pagani M: Evidence of autonomic dysregulation in otherwise healthy cancer caregivers: a possible link with health hazard. Eur J Cancer; 2008 Nov;44(16):2437-43
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  • [Title] Evidence of autonomic dysregulation in otherwise healthy cancer caregivers: a possible link with health hazard.
  • In this observational study, we addressed whether autonomic nervous system (ANS) regulation and perception of stress would be altered in a group of 58 health cancer caregivers as compared to 60 controls.
  • Caregivers show, in addition to signs of psychological involvement, a clear autonomic imbalance, suggestive of sympathetic predominance at rest and of a reduction of vagal cardiac regulation (overall gain of baroreflex -index alpha- was respectively of 17.5+/-1.5 versus 25.1+/-1.8 msec/mmHg, p<<0.02).
  • These data suggest possible preventive strategies, based on tailored treatments aiming at a betterment of individual autonomic profile.
  • [MeSH-major] Autonomic Nervous System Diseases / etiology. Caregivers / psychology. Neoplasms. Stress, Psychological / etiology

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  • (PMID = 18804998.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] WI4X0X7BPJ / Hydrocortisone
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15. Batchelor T, Loeffler JS: Primary CNS lymphoma. J Clin Oncol; 2006 Mar 10;24(8):1281-8
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  • Characteristic imaging features should be suggestive of the diagnosis, avoidance of corticosteroids, if possible, and early neurosurgical consultation for stereotactic biopsy.
  • Whole-brain radiation therapy (WBRT) alone is insufficient for durable tumor control and is associated with a high risk of neurotoxicity in patients older than age 60.
  • Neurotoxicity typically is associated with significant cognitive, motor, and autonomic dysfunction, and has a negative impact on quality of life.
  • Chemotherapy and WBRT together improve tumor response rates and survival compared with WBRT alone.
  • Methotrexate-based multiagent chemotherapy without WBRT is associated with similar tumor response rates and survival compared with regimens that include WBRT, although controlled trials have not been performed.
  • [MeSH-major] Central Nervous System Neoplasms. Lymphoma, Non-Hodgkin

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  • (PMID = 16525183.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 51
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16. Lindsley CW: Horner's Syndrome and Neuroblastoma: our family's odyssey with disorders of the sympathetic nervous system. ACS Chem Neurosci; 2010 Oct 20;1(10):649-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Horner's Syndrome and Neuroblastoma: our family's odyssey with disorders of the sympathetic nervous system.
  • [MeSH-major] Autonomic Nervous System Diseases / genetics. Brain Neoplasms / genetics. Horner Syndrome / genetics. Neuroblastoma / genetics
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Combined Modality Therapy. Early Diagnosis. Emergency Medical Services. Family. Female. Genes, myc / genetics. Humans. Infant. Neurosurgical Procedures. Prognosis. Tomography, X-Ray Computed


17. López-Miranda V, Herradón E, González C, Martín MI: Vascular toxicity of chemotherapeutic agents. Curr Vasc Pharmacol; 2010 Sep;8(5):692-700
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  • With respect to the cardiovascular system, cardiotoxicity is a well-described and potentially lethal side effect of certain chemotherapeutic agents, such as anthracyclines.
  • The exact mechanism of this toxicity is not known, and several possibilities, including vascular autonomic neuropathy and vascular damage, have been proposed.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Antineoplastic Agents / pharmacology. Blood Vessels / drug effects. Neoplasms / drug therapy. Vascular Diseases / chemically induced
  • [MeSH-minor] Animals. Autonomic Nervous System / drug effects. Drug Monitoring. Endothelium, Vascular / drug effects. Humans

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  • (PMID = 19758112.001).
  • [ISSN] 1875-6212
  • [Journal-full-title] Current vascular pharmacology
  • [ISO-abbreviation] Curr Vasc Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United Arab Emirates
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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18. Oishi Y, Nagai S, Yoshida M, Fujisawa S, Sazawa A, Shinohara N, Nonomura K, Matsuno K, Shimizu C: Mutation analysis of the SDHB and SDHD genes in pheochromocytomas and paragangliomas: identification of a novel nonsense mutation (Q168X) in the SDHB gene. Endocr J; 2010;57(8):745-50
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  • Pheochromocytoma (PCC) and paraganglioma (PGL) are tumors of the autonomic nervous system.
  • The former is a tumor that occurs in only adrenal glands, and the latter can be found in the head and neck or in the thorax and abdomen.
  • [MeSH-minor] Adolescent. Adrenal Gland Neoplasms / genetics. Adult. Aged. DNA Mutational Analysis. Female. Humans. Male. Middle Aged. Polymerase Chain Reaction. Polymorphism, Single Nucleotide. Sequence Analysis, DNA

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  • (PMID = 20505258.001).
  • [ISSN] 1348-4540
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Codon, Nonsense; 0 / SDHD protein, human; EC 1.3.5.1 / SDHB protein, human; EC 1.3.99.1 / Succinate Dehydrogenase
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19. Rao J, Yang J, Liu Z, Wang L, Yin Z, Liu L, He Q, Yang L: Hypothetic association between greater sympathetic activity and prostate cancer. Med Hypotheses; 2008 Sep;71(3):442-3
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  • In spite of substantial progress in research, diagnosis and treatment, the causes of prostate cancer remain largely unknown.
  • However, the specific mechanisms of changes of increased prostatic cell proliferation and carcinogenesis caused by the autonomic nervous system have not yet been clarified.
  • [MeSH-major] Aging / physiology. Prostatic Neoplasms / physiopathology. Sympathetic Nervous System / physiology


20. O'Connor TL, Kossoff E: Delayed seizure associated with paclitaxel-Cremophor el in a patient with early-stage breast cancer. Pharmacotherapy; 2009 Aug;29(8):993-6
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  • Neurologic toxicity is well described with both the drug and this carrier, with most toxicities manifesting as peripheral neuropathy, motor neuropathy, autonomic neuropathy, and myopathy.
  • Toxic effects on the central nervous system, such as seizures or encephalopathy, have been rarely reported; however, the seizures reported were closely related to the time of infusion.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / adverse effects. Breast Neoplasms / drug therapy. Glycerol / analogs & derivatives. Paclitaxel / adverse effects. Pharmaceutical Vehicles / adverse effects. Seizures / chemically induced

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  • (PMID = 19637953.001).
  • [ISSN] 1875-9114
  • [Journal-full-title] Pharmacotherapy
  • [ISO-abbreviation] Pharmacotherapy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Pharmaceutical Vehicles; 6D4M1DAL6O / cremophor EL; P88XT4IS4D / Paclitaxel; PDC6A3C0OX / Glycerol
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21. Hasegawa S, Nagayama S, Nomura A, Kawamura J, Sakai Y: Multimedia article. Autonomic nerve-preserving total mesorectal excision in the laparoscopic era. Dis Colon Rectum; 2008 Aug;51(8):1279-82
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  • [Title] Multimedia article. Autonomic nerve-preserving total mesorectal excision in the laparoscopic era.
  • PURPOSE: Although technically demanding, laparoscopy may be advantageous in magnifying the anatomy of the pelvic autonomic nervous system when performing total mesorectal excision for rectal cancer.
  • [MeSH-major] Autonomic Nervous System / physiology. Laparoscopy. Rectal Neoplasms / surgery

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  • (PMID = 18483826.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Kaestner F, Mostert C, Behnken A, Boeckermann I, Ternes F, Diedrich M, Zavorotnyy M, Arolt V, Weckesser M, Rothermundt M: Therapeutic strategies for catatonia in paraneoplastic encephalitis. World J Biol Psychiatry; 2008;9(3):236-40
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  • This report is about a 40-year-old man suffering from fluctuating catatonia as main symptom of long-lasting paraneoplastic encephalitis caused by a testicular neoplasm.
  • With recurrence of a neoplasm initially diagnosed as seminoma after a 7-year symptom-free interval the patient suddenly developed various neurological and psychopathological symptoms including seizures, autonomic dysregulation, continuous anterograde short-term amnesia and predominantly a long-lasting complex catatonic syndrome with on-off phenomena.
  • Further neoplasm recurrences, however, reinforced catatonia until the tumour was successfully treated and the patient fully recovered.
  • [MeSH-major] Catatonia / complications. Catatonia / therapy. Electroconvulsive Therapy / methods. Paraneoplastic Syndromes, Nervous System / complications. Paraneoplastic Syndromes, Nervous System / pathology
  • [MeSH-minor] Adult. Electroencephalography. Humans. Magnetic Resonance Imaging. Male. Plasmapheresis. Testicular Neoplasms / pathology

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  • (PMID = 17853266.001).
  • [ISSN] 1562-2975
  • [Journal-full-title] The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • [ISO-abbreviation] World J. Biol. Psychiatry
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Scotland
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23. Simonelli M, Banna GL, Santoro A: Thymoma associated with myasthenia and autonomic anti-Hu paraneoplastic neuropathy. Tumori; 2009 Mar-Apr;95(2):243-7
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  • [Title] Thymoma associated with myasthenia and autonomic anti-Hu paraneoplastic neuropathy.
  • Anti-Hu antibodies and a clinical "anti-Hu syndrome" characterized by encephalitis and/or painful neuropathies have been reported in only three patients at the time of the diagnosis of thymoma.
  • We describe a severe anti-Hu-related autonomic neuropathy with gastrointestinal paresis and intestinal pseudo-obstruction with malabsorption that occurred concomitantly with the worsening of myasthenic symptoms long after the initial diagnosis of thymoma in a young patient.
  • The clinical anti-Hu syndrome preceded the radiological diagnosis of thymoma recurrence.
  • [MeSH-major] Antibodies, Neoplasm / blood. Autonomic Nervous System Diseases / complications. ELAV Proteins / immunology. Myasthenia Gravis / complications. Paraneoplastic Polyneuropathy / complications. Thymoma / complications. Thymus Neoplasms / complications


24. Shim HB, Jung TY, Lee JK, Ku JH: Prostate activity and prostate cancer in spinal cord injury. Prostate Cancer Prostatic Dis; 2006;9(2):115-20
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  • In addition to androgen, autonomic nerves may be involved in prostatic function.
  • In addition, the impact of central nervous system injury on prostatic secretory activity, and consequently on serum PSA levels, is also not clear.
  • [MeSH-major] Androgens / metabolism. Prostate-Specific Antigen / blood. Prostatic Neoplasms / etiology. Spinal Cord Injuries / complications


25. Oh SJ, Hong YK, Song EK: Paroxysmal autonomic dysregulation with fever that was controlled by propranolol in a brain neoplasm patient. Korean J Intern Med; 2007 Mar;22(1):51-4
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  • [Title] Paroxysmal autonomic dysregulation with fever that was controlled by propranolol in a brain neoplasm patient.
  • Paroxysmal persistent hyperthermia after sudden mental change or neurologic deficit can develop via autonomic dysregulation without infection or any other causes of fever.
  • Paroxysmal hyperthermic autonomic dysregulation is a rare disease entity.
  • It manifests as a form of paroxysmal hypertension, fever, tachycardia, tachypnea, pupillary dilation, agitation and extensor posturing after traumatic brain injury, hydrocephalus, brain hemorrhage or brain neoplasm.
  • We recently experienced a case of paroxysmal hyperthermia following intracerebral hemorrhage along with brain neoplasm.
  • Propranolol is one of the most effective drugs for treating paroxysmal hyperthermia that is due to autonomic dysregulation.
  • [MeSH-major] Adrenergic beta-Antagonists / therapeutic use. Autonomic Nervous System Diseases / drug therapy. Brain Neoplasms / complications. Cerebral Hemorrhage / complications. Fever / drug therapy. Propranolol / therapeutic use

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  • (PMID = 17427648.001).
  • [ISSN] 1226-3303
  • [Journal-full-title] The Korean journal of internal medicine
  • [ISO-abbreviation] Korean J. Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Adrenergic beta-Antagonists; 9Y8NXQ24VQ / Propranolol
  • [Other-IDs] NLM/ PMC2687607
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26. Osaka K, Yokonishi T, Ito Y, Komiya A, Kobayashi K, Sakai N, Noguchi S, Kishi H, Tsuura Y: [A case of giant retroperitoneal paraganglioma]. Hinyokika Kiyo; 2010 Jul;56(7):377-80
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  • Paraganglioma is a rare neuroendocrine tumor which arises from extra adrenal paraganglionic cells of the autonomic nervous system.
  • Angiography showed the left renal, splenic, middle suprarenal and left inferior diaphragmatic artery feeding the tumor.
  • The tumor, left kidney, adrenal gland and spleen were surgically resected.
  • Histological examination revealed extra-adrenal paraganglioma, and there was no invasion of the tumor to the left kidney, adrenal gland and spleen.
  • The patient has now survived more than 10 months following the surgery without tumor recurrence.
  • [MeSH-major] Paraganglioma / pathology. Retroperitoneal Neoplasms / pathology

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  • (PMID = 20724811.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 13
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27. Watanabe N, Moriwaki K: Preoperative anticipation of origin from MRI scans in cervical phrenic schwannoma. Auris Nasus Larynx; 2005 Mar;32(1):85-8
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  • Schwannomas of the head and neck are uncommon tumors that arise from any peripheral, cranial or autonomic nerve.
  • [MeSH-major] Magnetic Resonance Imaging. Neurilemmoma / pathology. Peripheral Nervous System Neoplasms / pathology. Phrenic Nerve / pathology. Preoperative Care

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  • (PMID = 15882833.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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28. Bernardos García L, García Marín A, Vaquero Rodríguez A, Serralta de Colsa D, Turégano Fuentes F: [Gastrointestinal autonomic nerve tumors]. Rev Esp Enferm Dig; 2008 Dec;100(12):803-4
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  • [Title] [Gastrointestinal autonomic nerve tumors].
  • [MeSH-major] Colonic Neoplasms / pathology. Gastrointestinal Stromal Tumors / pathology
  • [MeSH-minor] Adult. Autonomic Nervous System / pathology. Female. Humans. Male. Middle Aged

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  • (PMID = 19222345.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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29. Blaes F, Tschernatsch M: Paraneoplastic neurological disorders. Expert Rev Neurother; 2010 Oct;10(10):1559-68
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  • The article provides an overview on the diagnosis and pathogenesis of paraneoplastic neurological disorders (PNDs), and subsequently the current therapeutic strategies in these patients.
  • PNDs are nervous system dysfunctions in cancer patients, which are not due to a local effect of the tumor or its metastases.
  • Whereas the most central nervous PNDs are more T-cell-mediated, limbic encephalitis can be caused by pathogenic receptor autoantibodies.
  • The PND of the neuromuscular junction and paraneoplastic autonomic neuropathy are mainly associated with receptor or ion channel autoantibodies.
  • By contrast, most CNS PNDs associated with defined antineuronal antibodies directed against intracellular antigens only stabilize after tumor treatment.
  • [MeSH-major] Autoantibodies / immunology. Autoantibodies / physiology. Paraneoplastic Syndromes, Nervous System / diagnosis. Paraneoplastic Syndromes, Nervous System / physiopathology
  • [MeSH-minor] Central Nervous System Diseases / complications. Central Nervous System Diseases / immunology. Female. Humans. Lung Neoplasms / complications. Lung Neoplasms / immunology. Male. Nerve Tissue Proteins / immunology. Nervous System Diseases / complications. Nervous System Diseases / immunology. Paraneoplastic Polyneuropathy / complications. Paraneoplastic Polyneuropathy / immunology

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  • (PMID = 20925471.001).
  • [ISSN] 1744-8360
  • [Journal-full-title] Expert review of neurotherapeutics
  • [ISO-abbreviation] Expert Rev Neurother
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Nerve Tissue Proteins
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30. An MM, Zou Z, Shen H, Liu P, Chen ML, Cao YB, Jiang YY: Incidence and risk of significantly raised blood pressure in cancer patients treated with bevacizumab: an updated meta-analysis. Eur J Clin Pharmacol; 2010 Aug;66(8):813-21
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  • The risk may be dose-dependent and vary with tumor type.
  • [MeSH-major] Antibodies, Monoclonal / adverse effects. Autonomic Nervous System Diseases / epidemiology. Cardiovascular Diseases / epidemiology. Hypertension / chemically induced. Meta-Analysis as Topic. Neoplasms / drug therapy
  • [MeSH-minor] Antibodies, Monoclonal, Humanized. Bevacizumab. Breast Neoplasms / chemically induced. Breast Neoplasms / drug therapy. Carcinoma, Renal Cell / chemically induced. Carcinoma, Renal Cell / drug therapy. Female. Humans. Incidence. Randomized Controlled Trials as Topic. Risk Factors. Vascular Endothelial Growth Factor A / therapeutic use

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  • (PMID = 20401474.001).
  • [ISSN] 1432-1041
  • [Journal-full-title] European journal of clinical pharmacology
  • [ISO-abbreviation] Eur. J. Clin. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Vascular Endothelial Growth Factor A; 2S9ZZM9Q9V / Bevacizumab
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31. Yun AJ, Bazar KA, Lee PY, Gerber A, Daniel SM: The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine. Med Hypotheses; 2005;64(6):1073-9
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  • [Title] The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine.
  • We hypothesize that the illnesses associated with smoking may be partly attributable to autonomic dysfunction, sympathetic bias, and T helper (Th)2 inflammation induced by a paradoxical compensatory response to intermittent nicotinic exposure.
  • Other conditions associated with tobacco exposure may also operate through similar autonomic and immune dysfunctions.
  • [MeSH-major] Autonomic Nervous System / physiopathology. Models, Biological. Nicotine / adverse effects. Smoking / adverse effects. Substance Withdrawal Syndrome / physiopathology. Tobacco, Smokeless / adverse effects
  • [MeSH-minor] Anxiety / chemically induced. Anxiety / physiopathology. Humans. Hypertension / chemically induced. Hypertension / physiopathology. Inflammation / chemically induced. Inflammation / physiopathology. Neoplasms / etiology. Receptors, Nicotinic / drug effects. Receptors, Nicotinic / physiology. Sleep Initiation and Maintenance Disorders / chemically induced. Sleep Initiation and Maintenance Disorders / physiopathology. Smoking Cessation. Sympathetic Nervous System / drug effects. Sympathetic Nervous System / physiopathology. Tachycardia / chemically induced. Tachycardia / physiopathology. Th2 Cells / immunology. Tumor Escape. Vagus Nerve / physiopathology

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  • (PMID = 15823687.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Receptors, Nicotinic; 6M3C89ZY6R / Nicotine
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32. Kenemans P, Kubista E, Foidart JM, Yip CH, von Schoultz B, Sismondi P, Vassilopoulou-Sellin R, Beckmann MW, Bundred NJ, Egberts J, van Os S, Planellas J: Safety of tibolone in the treatment of vasomotor symptoms in breast cancer patients--design and baseline data 'LIBERATE' trial. Breast; 2007 Dec;16 Suppl 2:S182-9
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  • For the primary tumor, Stage IIA or higher was reported for >70% of the patients.
  • [MeSH-major] Antineoplastic Agents, Hormonal / pharmacology. Autonomic Nervous System Diseases / drug therapy. Breast Neoplasms / drug therapy. Norpregnenes / pharmacology. Vasomotor System / drug effects
  • [MeSH-minor] Aromatase Inhibitors / adverse effects. Aromatase Inhibitors / pharmacology. Aromatase Inhibitors / therapeutic use. Bone Density. Double-Blind Method. Female. Humans. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Quality of Life. Survival Analysis. Tamoxifen / adverse effects. Tamoxifen / pharmacology. Tamoxifen / therapeutic use. Treatment Outcome

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  • [ErratumIn] Breast. 2008 Apr;17(2):214-5. Egberts, J [added]; van Os, S [added]; Planellas, J [added]
  • (PMID = 17983942.001).
  • [ISSN] 0960-9776
  • [Journal-full-title] Breast (Edinburgh, Scotland)
  • [ISO-abbreviation] Breast
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Aromatase Inhibitors; 0 / Norpregnenes; 094ZI81Y45 / Tamoxifen; FF9X0205V2 / tibolone
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33. Cheshire WP, Odell JA, Woodward TA, Wharen RE Jr: Cervical sympathetic neuralgia arising from a schwannoma. Headache; 2007 Mar;47(3):444-6
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  • Autonomic testing demonstrated signs of increased vasomotor and sudomotor activity in the left palm.
  • [MeSH-major] Autonomic Nervous System Diseases / complications. Face. Nervous System Neoplasms / complications. Neuralgia / etiology. Neurilemmoma / complications. Shoulder


34. Unal M, Polat A, Pata YS, Vayisoğlu Y, Yildiz A, Ismi O: Paraganglioma of the skull base: a case report. Auris Nasus Larynx; 2007 Sep;34(3):427-30
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  • Paragangliomas are rare benign neuroendocrine tumors derived from the extra-adrenal paraganglia of the autonomic nervous system.
  • [MeSH-major] Paraganglioma / diagnosis. Skull Base Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biopsy. Chromogranin A / analysis. Endoscopy. Female. Humans. Magnetic Resonance Imaging. Respiratory Insufficiency / etiology. S100 Proteins / analysis. Skull Base / pathology. Synaptophysin / analysis. Tomography, X-Ray Computed. Vocal Cord Paralysis / etiology

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  • (PMID = 17331688.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranin A; 0 / S100 Proteins; 0 / Synaptophysin
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35. Kakuta Y, Kawamura N, Fukuhara S, Imazu T, Hara T, Yamaguchi S, Adachi S: [Case of retroperitoneal paraganglioma]. Hinyokika Kiyo; 2007 Nov;53(11):801-4
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  • Paragangliomas are rare neuroendocrine tumors that arise from hyperplastic paraganglionic cells and occur in or near the ganglia of the autonomic nervous system.
  • There was no pedicle and no connection of the tumor to the abdominal or retroperitoneal organs.
  • Complete excision of the tumor was performed smoothly.
  • Nine months after surgery, there were no signs of tumor recurrence.
  • [MeSH-major] Paraganglioma / surgery. Retroperitoneal Neoplasms / surgery
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Catecholamines / analysis. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18051805.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Catecholamines
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36. Dhamija R, Tan KM, Pittock SJ, Foxx-Orenstein A, Benarroch E, Lennon VA: Serologic profiles aiding the diagnosis of autoimmune gastrointestinal dysmotility. Clin Gastroenterol Hepatol; 2008 Sep;6(9):988-92
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  • [Title] Serologic profiles aiding the diagnosis of autoimmune gastrointestinal dysmotility.
  • BACKGROUND & AIMS: Autoimmune gastrointestinal dysmotility is a limited autoimmune dysautonomia occurring idiopathically or in the context of an anatomically remote neoplasm, previously documented or unsuspected.
  • Here we report 24 Mayo Clinic patients in whom the profile of serum autoantibodies aided this diagnosis.
  • CONCLUSIONS: Autoimmune serology aids the diagnosis of autoimmune gastrointestinal dysmotility, both paraneoplastic and idiopathic, and might guide management.

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  • (PMID = 18599359.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / DK068055-05; United States / NIDDK NIH HHS / DK / P01 DK068055; United States / NIDDK NIH HHS / DK / DK68055; United States / NIDDK NIH HHS / DK / P01 DK068055-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies
  • [Other-IDs] NLM/ NIHMS85857; NLM/ PMC2741093
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37. Bazar KA, Yun AJ, Lee PY: "Starve a fever and feed a cold": feeding and anorexia may be adaptive behavioral modulators of autonomic and T helper balance. Med Hypotheses; 2005;64(6):1080-4
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  • [Title] "Starve a fever and feed a cold": feeding and anorexia may be adaptive behavioral modulators of autonomic and T helper balance.
  • Since fever may be an adaptation to fight bacteria and "colds" are generally viral in origin, the adage "starve a fever and feed a cold" may reflect a sensible behavioral strategy to tilt autonomic and Th balance in directions that are optimal for fighting the particular type of infection.
  • The ability to modulate T helper balance through the neurohormonal and autonomic axis by adjusting food intake may be the mechanism behind other unexplained clinical observations such as the improved outcomes of ICU patients after enteric versus parenteric feedings.
  • Modulating feeding, hydration, and sleep may prove beneficial in treating other conditions associated with abnormal autonomic and Th balance.
  • [MeSH-major] Adaptation, Physiological / immunology. Anorexia / immunology. Autonomic Nervous System / physiology. Feeding Behavior / physiology. Models, Immunological. Th2 Cells / immunology
  • [MeSH-minor] Bacterial Infections / diet therapy. Bacterial Infections / epidemiology. Bacterial Infections / immunology. Bacterial Infections / therapy. Biological Evolution. Cachexia / etiology. Cachexia / physiopathology. Energy Intake. Fever / diet therapy. Fever / immunology. Fluid Therapy. Humans. Inflammation / immunology. Lymphocyte Count. Neoplasms / epidemiology. Neoplasms / immunology. Sleep / physiology. Th1 Cells / immunology. Virus Diseases / diet therapy. Virus Diseases / epidemiology. Virus Diseases / immunology. Virus Diseases / therapy

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  • (PMID = 15823688.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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38. Burnstock G: Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev; 2006 Mar;58(1):58-86
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  • The concept of a purinergic signaling system, using purine nucleotides and nucleosides as extracellular messengers, was first proposed over 30 years ago.
  • Plasticity of purinoceptor expression in pathological conditions is frequently observed, including an increase in the purinergic component of autonomic cotransmission.
  • [MeSH-minor] Animals. Cardiovascular Diseases. Endocrine System. Female Urogenital Diseases. Gastrointestinal Tract. Humans. Immune System. Inflammation. Male Urogenital Diseases. Musculoskeletal Diseases. Neoplasms. Nervous System Diseases. Respiratory Tract Diseases. Signal Transduction. Skin

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  • (PMID = 16507883.001).
  • [ISSN] 0031-6997
  • [Journal-full-title] Pharmacological reviews
  • [ISO-abbreviation] Pharmacol. Rev.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Purinergic P2
  • [Number-of-references] 420
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39. Shen J, Horii Y, Fujisaki Y, Nagai K: Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation. Auton Neurosci; 2009 May 11;147(1-2):86-90
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  • [Title] Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation.
  • Oral supplementations of L-arginine and L-lysine show tumor inhibition abilities.
  • An increase in splenic-SNA and tumor volume (2 mM), no effect (10 mM), and a decrease in both values (50 mM) were seen.
  • Bivariate correlation analysis revealed a positive correlation between changes in splenic-SNA and tumor volume, indicating the tumor suppressing ability of weakened splenic-SNA.
  • [MeSH-major] Arginine / pharmacology. Immune Tolerance / drug effects. Lysine / pharmacology. Neoplasms / drug therapy. Neuroimmunomodulation / drug effects. Sympathetic Nervous System / drug effects
  • [MeSH-minor] Animals. Antineoplastic Agents / pharmacology. Antineoplastic Agents / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / pharmacology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma / drug therapy. Carcinoma / immunology. Carcinoma / physiopathology. Cell Proliferation / drug effects. Colonic Neoplasms / drug therapy. Colonic Neoplasms / immunology. Colonic Neoplasms / physiopathology. Disease Models, Animal. Female. Humans. Immunologic Factors / pharmacology. Immunologic Factors / therapeutic use. Killer Cells, Natural / immunology. Male. Mice. Mice, Inbred BALB C. Rats. Rats, Wistar. Spleen / cytology. Spleen / immunology. Spleen / innervation. Treatment Outcome

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  • (PMID = 19237319.001).
  • [ISSN] 1872-7484
  • [Journal-full-title] Autonomic neuroscience : basic & clinical
  • [ISO-abbreviation] Auton Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Immunologic Factors; 94ZLA3W45F / Arginine; K3Z4F929H6 / Lysine
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40. McKeon A, Lennon VA, Lachance DH, Fealey RD, Pittock SJ: Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments. Arch Neurol; 2009 Jun;66(6):735-41
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  • CONCLUSION: The detection of alpha3-AChR autoantibody aids the diagnosis of neurological autoimmunity and cancer.

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  • (PMID = 19506133.001).
  • [ISSN] 1538-3687
  • [Journal-full-title] Archives of neurology
  • [ISO-abbreviation] Arch. Neurol.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / P01 DK068055; United States / NIDDK NIH HHS / DK / R01 DK071209; United States / NIDDK NIH HHS / DK / P01-DK68055; United States / NIDDK NIH HHS / DK / R01-DK71209-4
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Biomarkers; 0 / Receptors, Nicotinic; 0 / nicotinic receptor subunit alpha3
  • [Other-IDs] NLM/ NIHMS507357; NLM/ PMC3764484
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41. Lwu S, Midha R: Clinical examination of brachial and pelvic plexus tumors. Neurosurg Focus; 2007;22(6):E5
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  • Presenting complaints may include a palpable mass lesion, either symptomatic or asymptomatic; sensory alterations; pain; motor deficits; visceral symptoms; or autonomic dysfunction.
  • Complete and accurate clinical information must be gathered to pinpoint the anatomical localization of the lesion and formulate a differential diagnosis.
  • [MeSH-major] Brachial Plexus / pathology. Hypogastric Plexus / pathology. Neurologic Examination / methods. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 17613222.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 9
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42. Masaki T, Takayama M, Matsuoka H, Abe N, Ueki H, Sugiyama M, Tonari A, Kusuda J, Mizumoto S, Atomi Y: Intraoperative radiotherapy for oncological and function-preserving surgery in patients with advanced lower rectal cancer. Langenbecks Arch Surg; 2008 Mar;393(2):173-80
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  • BACKGROUND: Pelvic autonomic nerve preservation (PANP) with lateral lymph node dissection (LLND) has been introduced in rectal cancer surgery in Japan; however, its indication has not been standardized yet.
  • [MeSH-major] Autonomic Nervous System / surgery. Intraoperative Care. Lymph Node Excision. Microsurgery. Pelvis / innervation. Rectal Neoplasms / radiotherapy. Rectal Neoplasms / surgery. Rectum / innervation
  • [MeSH-minor] Aged. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Japan. Kaplan-Meier Estimate. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Neoplasm Recurrence, Local / mortality. Neoplasm Staging. Postoperative Complications / etiology. Postoperative Complications / mortality. Prognosis. Radiotherapy, Adjuvant. Risk Factors. Urinary Catheterization. Urination Disorders / etiology

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  • (PMID = 18172677.001).
  • [ISSN] 1435-2451
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
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43. Scottish Bone Tumor Registry, Sharma H, Mehdi SA, MacDuff E, Reece AT, Jane MJ, Reid R: Paget sarcoma of the spine: Scottish Bone Tumor Registry experience. Spine (Phila Pa 1976); 2006 May 20;31(12):1344-50
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  • [Title] Paget sarcoma of the spine: Scottish Bone Tumor Registry experience.
  • STUDY DESIGN: Retrospective case study of 13 cases of Paget sarcoma of the spine accrued from a prospectively collected Tumor Registry database.
  • METHODS: Between January 1944 and December 2003, 89 patients were registered with a diagnosis of Paget sarcoma in the Scottish Bone Tumor Registry.
  • The mode of presentation was progressively increasing low back pain (in all 13), unilateral sciatica (six; left-sided, five; right-sided, one), bilateral sciatica (two), lower limb weakness (eight), and autonomic dysfunction (four).
  • [MeSH-major] Lumbar Vertebrae. Osteitis Deformans. Sacrum. Sarcoma. Spinal Neoplasms
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Nerve Compression Syndromes / complications. Nerve Compression Syndromes / etiology. Nervous System Diseases / etiology. Registries. Retrospective Studies. Spinal Cord Compression / complications. Spinal Cord Compression / etiology. Spinal Nerve Roots. Survival Analysis. Tomography, X-Ray Computed


44. Martin E, Pointreau Y, Roche-Forestier S, Barillot I: [Normal tissue tolerance to external beam radiation therapy: small bowel]. Cancer Radiother; 2010 Jul;14(4-5):350-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Abdominal Neoplasms / radiotherapy. Autonomic Nervous System / radiation effects. Diarrhea / etiology. Diarrhea / radionuclide imaging. Digestion / physiology. Digestion / radiation effects. Humans. Intestinal Absorption / radiation effects. Muscle, Smooth / radiation effects. Neoplasm Metastasis / radionuclide imaging. Pain / etiology. Pain / radionuclide imaging. Pelvic Neoplasms / radiotherapy. Radiation, Ionizing. Radiotherapy Dosage. Risk Factors

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  • [Copyright] Copyright (c) 2010 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.
  • [CommentIn] Cancer Radiother. 2011 Jun;15(3):258-9 [21489845.001]
  • (PMID = 20598616.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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45. Thor PJ, Furgala A, Pach R, Hubalewska-Dydejczyk A, Mazur M, Matyja A, Kulig J, Huszno B: Antral gastric motility impairement and autonomic nervous system dysfunction in patients with pancreatic cancer (preliminary results). Folia Med Cracov; 2006;47(1-4):61-8
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  • [Title] Antral gastric motility impairement and autonomic nervous system dysfunction in patients with pancreatic cancer (preliminary results).
  • The aim of the study was to evaluate the influence of pancreatic carcinoma on gastric motility and autonomic system activity in patients before surgery.
  • Antral distribution of meal suggests the presence of impaired proximal gastric response to meal due to diminished autonomic nervous system function and impaired myoelectric gastric activity in patients with pancreatic cancer.
  • [MeSH-major] Pancreatic Neoplasms / complications. Pyloric Antrum / physiopathology. Stomach Diseases / etiology
  • [MeSH-minor] Aged. Autonomic Nervous System Diseases / etiology. Autonomic Nervous System Diseases / physiopathology. Female. Gastric Emptying / drug effects. Humans. Male. Middle Aged. Pancreatectomy. Pancreatic Hormones / metabolism. Pancreatic Hormones / pharmacology. Pilot Projects. Preoperative Care

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  • (PMID = 18038613.001).
  • [ISSN] 0015-5616
  • [Journal-full-title] Folia medica Cracoviensia
  • [ISO-abbreviation] Folia Med Cracov
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Pancreatic Hormones
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46. Rich T, Innominato PF, Boerner J, Mormont MC, Iacobelli S, Baron B, Jasmin C, Lévi F: Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer. Clin Cancer Res; 2005 Mar 1;11(5):1757-64
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  • Actigraphy patterns were correlated with QOL indices, serum cortisol obtained at 8:00 a.m. and 4:00 p.m. and with serum levels of transforming growth factor-alpha, tumor necrosis factor-alpha, and interleukin 6 (IL-6) obtained at 8:00 a.m. and analyzed in duplicate by ELISA.
  • CONCLUSIONS: Significant correlations were found between serum levels of TGF-alpha and IL-6, circadian patterns in wrist activity and serum cortisol and tumor-related symptoms in patients with metastatic colorectal cancer.
  • These data support the hypothesis that some cancer patient's symptoms of fatigue, poor QOL, and treatment outcome are related to tumor or host generated cytokines and could reflect cytokine effects on the circadian timing system.
  • This interplay between cytokine signaling pathways, the hypothalamic-pituitary-adrenal axis, the autonomic nervous system, and efferent pathways of the suprachiasmatic nucleus that control circadian physiology, opens the way to new rational interventions for symptom management in cancer patients.
  • [MeSH-major] Circadian Rhythm. Colorectal Neoplasms / immunology. Colorectal Neoplasms / psychology. Interleukin-6 / blood. Neoplasm Metastasis. Transforming Growth Factor alpha / blood. Tumor Necrosis Factor-alpha / analysis

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  • (PMID = 15755997.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01 RR 00847
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interleukin-6; 0 / Transforming Growth Factor alpha; 0 / Tumor Necrosis Factor-alpha; WI4X0X7BPJ / Hydrocortisone
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47. Yun AJ, Lee PY, Bazar KA: Clinical benefits of hydration and volume expansion in a wide range of illnesses may be attributable to reduction of sympatho-vagal ratio. Med Hypotheses; 2005;64(3):646-50
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  • Interestingly, isotonic or hypertonic hydration, rather than a low-salt diet, may be a counterintuitive potential strategy to treat some cases of hypertension associated with dehydration and autonomic dysfunction.
  • [MeSH-major] Blood Volume. Disease. Fluid Therapy. Sympathetic Nervous System / physiology. Vagus Nerve / physiology
  • [MeSH-minor] Asthma / therapy. Coronary Disease / therapy. Humans. Neoplasms / therapy. Stroke / therapy

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  • (PMID = 15617881.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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48. Huda MS, Mani H, Dovey T, Halford JC, Boyland E, Daousi C, Wilding JP, Pinkney J: Ghrelin inhibits autonomic function in healthy controls, but has no effect on obese and vagotomized subjects. Clin Endocrinol (Oxf); 2010 Nov;73(5):678-85
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  • [Title] Ghrelin inhibits autonomic function in healthy controls, but has no effect on obese and vagotomized subjects.
  • OBJECTIVE: Ghrelin inhibits sympathetic nervous system (SNS) activity in rodents.
  • Total power (TP) represents overall autonomic function, low-frequency (LF) power represents sympathetic and parasympathetic activity, and high-frequency (HF) power represents parasympathetic activity.
  • CONCLUSIONS: Ghrelin inhibits SNS activity in healthy controls with a moderate effect on parasympathetic nervous system activity but had no effect on obese subjects.
  • [MeSH-major] Autonomic Nervous System / physiology. Ghrelin / pharmacology. Obesity, Morbid / physiopathology. Vagus Nerve / physiology
  • [MeSH-minor] Adult. Aged. Blood Glucose / metabolism. Blood Pressure / drug effects. Cross-Over Studies. Female. Gastrectomy. Heart Rate / drug effects. Humans. Insulin / blood. Male. Middle Aged. Parasympathetic Nervous System / drug effects. Parasympathetic Nervous System / physiopathology. Stomach Neoplasms / surgery. Sympathetic Nervous System / drug effects. Sympathetic Nervous System / physiopathology. Thermogenesis / drug effects. Vagotomy

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 20738316.001).
  • [ISSN] 1365-2265
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Ghrelin; 0 / Insulin
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49. Colović R, Micev M, Radak V, Grubor N, Colović N, Latincić S: [Stromal tumour of duodenal autonomous nerves (plexosarcoma)]. Srp Arh Celok Lek; 2007 May-Jun;135(5-6):330-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Autonomic Nervous System Diseases / pathology. Duodenal Neoplasms / pathology. Gastrointestinal Stromal Tumors / pathology. Peripheral Nervous System Neoplasms / pathology


50. Bech AP, Zandbergen EG, Mattijssen EJ: [Pathophysiology of one warm foot. Anatomy of the autonomic nervous system]. Ned Tijdschr Geneeskd; 2010;154:A1473
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  • [Title] [Pathophysiology of one warm foot. Anatomy of the autonomic nervous system].
  • In most people this location is the site of the lumbar paravertebral ganglia (an important part of the sympathetic nervous system).
  • The fact that these ganglia were affected by the tumour explained the autonomic dysfunction in this case.
  • Exploration of the symptoms with respect to the pathophysiology and anatomy of the autonomous nervous system might have led to an earlier diagnosis.
  • [MeSH-major] Autonomic Nervous System / anatomy & histology. Autonomic Nervous System Diseases / etiology. Foot / innervation. Neoplasms, Germ Cell and Embryonal / complications. Retroperitoneal Neoplasms / complications
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Diagnosis, Differential. Ganglia, Sympathetic / pathology. Humans. Male. Middle Aged. Sweating. Sympathetic Nervous System / pathology. Treatment Outcome

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  • (PMID = 20356421.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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51. Saadat P, Cesnorek S, Ram R, Kelly L, Vadmal M: Primary cutaneous paraganglioma of the scalp. J Am Acad Dermatol; 2006 May;54(5 Suppl):S220-3
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  • Paragangliomas are neuroendocrine tumors that arise in relation to the sympathetic or parasympathetic ganglia of the autonomic nervous system.
  • The tumor was studied histologically, immunohistochemically, and ultrastructurally.
  • [MeSH-major] Paraganglioma / pathology. Scalp. Skin Neoplasms / pathology

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  • (PMID = 16631945.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Kunitz A, Pahl S, Podrabsky P, Wardelmann E, Sturm I: Large paraganglioma of the abdominal cavity: a case report and review of the literature. Onkologie; 2010;33(7):377-80
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  • BACKGROUND: Paragangliomas are rare tumors that derive from cells of the autonomic nervous system.
  • CASE REPORT: We report a case of an oligosymptomatic 50-year-old man presenting with a large intraabdominal tumor mass measuring 24 x 22 x 12 cm.
  • Core needle biopsy revealed a tumor of mesenchymal origin with no clear-line differentiation, so the highly vascularized tumor was resected after embolization of the tumor vessels.
  • Differential diagnosis included histiocytic sarcoma and c-kit-negative gastrointestinal stromal tumor; the final diagnosis was paraganglioma.
  • CONCLUSIONS: Paraganglioma is a rare disease and should be considered in the differential diagnosis of abdominal masses.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Paraganglioma / diagnosis
  • [MeSH-minor] Angiography. Biomarkers, Tumor / analysis. Diagnosis, Differential. Embolization, Therapeutic. Follow-Up Studies. Humans. Infant, Newborn. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20631484.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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53. Mogler C, Kohlhof P, Penzel R, Grenacher L, Haag GM, Schirmacher P, Mueller W: A primary malignant ependymoma of the abdominal cavity: a case report and review of the literature. Virchows Arch; 2009 Apr;454(4):475-8
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  • Ependymomas generally arise in the central nervous system (CNS).
  • Careful reevaluation together with extensive review of the literature and comparison of related cases established the diagnosis after treatment failure and tumor progression.
  • The tumor was large and firm with some small cysts and showed pseudorosettes with strong glial fibrillary acidic protein (GFAP) expression.
  • In conclusion, primary extraneural ependymomas have to be included into the differential diagnosis of abdominal tumors with pseudorosette-formation, even in unusual sites, and GFAP-immunohistochemistry (IHC) supports the diagnosis.
  • [MeSH-major] Abdominal Cavity / pathology. Diagnostic Errors. Ependymoma / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Autonomic Pathways / pathology. Combined Modality Therapy. Digestive System Surgical Procedures. Female. Gastrointestinal Neoplasms / pathology. Glial Fibrillary Acidic Protein / biosynthesis. Humans. Immunohistochemistry. Peripheral Nervous System Neoplasms / pathology

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  • (PMID = 19238432.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 15
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54. Le Foll J, Pelletier A: [Psychiatric symptoms of a paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis: A case report]. Encephale; 2010 Apr;36(2):166-71
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  • BACKGROUND: Paraneoplastic encephalitis usually begins with a prodromal phase, followed first by prominent psychiatric symptoms or, less frequently, short-term memory loss, seizure, catatonia-like symptoms, dyskynesias and, secondly, by autonomic instability and central hypoventilation requiring intensive care.
  • [MeSH-major] Autoantibodies / cerebrospinal fluid. Ovarian Neoplasms / psychology. Paraneoplastic Syndromes, Nervous System / diagnosis. Paraneoplastic Syndromes, Nervous System / psychology. Receptors, N-Methyl-D-Aspartate / immunology. Teratoma / diagnosis. Teratoma / psychology
  • [MeSH-minor] Bipolar Disorder / diagnosis. Bipolar Disorder / immunology. Bipolar Disorder / psychology. Brain / pathology. Diagnostic Errors. Female. Humans. Magnetic Resonance Imaging. Neurologic Examination. Patient Care Team. Tomography, X-Ray Computed. Young Adult

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  • [Copyright] 2009 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.
  • (PMID = 20434635.001).
  • [ISSN] 0013-7006
  • [Journal-full-title] L'Encéphale
  • [ISO-abbreviation] Encephale
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Receptors, N-Methyl-D-Aspartate
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55. Krarup-Hansen A, Helweg-Larsen S, Schmalbruch H, Rørth M, Krarup C: Neuronal involvement in cisplatin neuropathy: prospective clinical and neurophysiological studies. Brain; 2007 Apr;130(Pt 4):1076-88
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  • Motor conduction studies, autonomic function and warm and cold temperature sensation remained unchanged at all doses of cisplatin treatment.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Carcinoma, Embryonal / drug therapy. Cisplatin / adverse effects. Neurons, Afferent / drug effects. Peripheral Nervous System Diseases / chemically induced. Testicular Neoplasms / drug therapy

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  • (PMID = 17301082.001).
  • [ISSN] 1460-2156
  • [Journal-full-title] Brain : a journal of neurology
  • [ISO-abbreviation] Brain
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
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56. Furgała A, Thor PJ, Mazur M, Pach R, Matyja A, Kulig J: [Gastric motility disorders in patients after pancreatoduodenectomy]. Folia Med Cracov; 2008;49(3-4):37-48
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the patients with cancer pancreatoduodenectomy causes disorders of gastric myoelectric activity, gastric motility and autonomic nervous system function.
  • [MeSH-major] Gastrointestinal Motility. Gastroparesis / diagnosis. Gastroparesis / etiology. Pancreaticoduodenectomy / adverse effects
  • [MeSH-minor] Aged. Autonomic Nervous System / physiopathology. Case-Control Studies. Electrodiagnosis / methods. Electromyography / methods. Female. Gastrointestinal Tract / physiopathology. Humans. Male. Middle Aged. Pancreatic Neoplasms / surgery. Postoperative Complications / diagnosis. Tomography, Emission-Computed / methods

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  • (PMID = 20050577.001).
  • [ISSN] 0015-5616
  • [Journal-full-title] Folia medica Cracoviensia
  • [ISO-abbreviation] Folia Med Cracov
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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57. Rosado Caracena R, Uña Orejón R, Garrido Ortega P, Pérez Andujar JA, Criado Jiménez A: [Convulsions in the operating room in a man with AIDS]. Rev Esp Anestesiol Reanim; 2009 Feb;56(2):108-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / complications. Epilepsy, Tonic-Clonic / etiology. Intraoperative Complications / etiology. Intubation, Gastrointestinal / adverse effects. Pulmonary Edema / etiology. Tonsillar Neoplasms / surgery
  • [MeSH-minor] AIDS-Related Opportunistic Infections / diagnosis. Acute Disease. Anti-HIV Agents / pharmacokinetics. Autonomic Nervous System Diseases / etiology. Autonomic Nervous System Diseases / physiopathology. Diagnosis, Differential. Drug Interactions. Humans. Lidocaine / adverse effects. Lidocaine / pharmacokinetics. Male. Middle Aged. Neck Dissection. Neoplasms, Second Primary / complications. Neoplasms, Second Primary / surgery. Sarcoma, Kaposi. Tonsillectomy. Tracheotomy

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  • (PMID = 19334659.001).
  • [ISSN] 0034-9356
  • [Journal-full-title] Revista española de anestesiología y reanimación
  • [ISO-abbreviation] Rev Esp Anestesiol Reanim
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Anti-HIV Agents; 98PI200987 / Lidocaine
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58. Furgała A, Madroszkiewicz D, Madroszkiewicz E, Gościński I, Kolasińska-Kloch W, Moskała M, Thor PJ: Autonomic system disturbances in patients with increased intracranial pressure caused by brain tumors evaluated by heart rate variability. Folia Med Cracov; 2007;48(1-4):35-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Autonomic system disturbances in patients with increased intracranial pressure caused by brain tumors evaluated by heart rate variability.
  • Most of the disturbances of autonomic system (AS) activity seen in clinical practice result from head injury are due to development of increased intracranial pressure (ICP).
  • Our results provided evidence that all patients with increased ICP had the autonomic system disturbances.
  • The heart rate variability and cardiovascular reflexes are useful in identification of autonomic system dysfunction.
  • [MeSH-major] Autonomic Nervous System Diseases / etiology. Brain Neoplasms / complications. Intracranial Aneurysm / etiology
  • [MeSH-minor] Autonomic Nervous System / physiopathology. Female. Heart Rate. Humans. Male. Middle Aged


59. Aszalós Z: [Some neurological and psychiatric complications of the disorders of the hypothalamo-hypophyseal system]. Orv Hetil; 2007 Apr 22;148(16):723-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Some neurological and psychiatric complications of the disorders of the hypothalamo-hypophyseal system].
  • Connection between the central nervous system and the endocrine system is extremely complex.
  • The hypothalamus serves as a crucial centre for the integration and coordination of autonomic functions by neuronal and hormonal pathways.
  • [MeSH-major] Hypothalamic Diseases / complications. Hypothalamic Hormones / metabolism. Hypothalamo-Hypophyseal System / physiopathology. Mental Disorders / etiology. Nervous System Diseases / etiology. Pituitary Diseases / complications. Pituitary Hormones / metabolism
  • [MeSH-minor] Humans. Pituitary Neoplasms / complications


60. Saleh TM, Connell BJ: Role of oestrogen in the central regulation of autonomic function. Clin Exp Pharmacol Physiol; 2007 Sep;34(9):827-32
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  • [Title] Role of oestrogen in the central regulation of autonomic function.
  • There is unquestionable evidence that oestrogen has both potent and long-lasting effects on several vital organ systems, including the cardiovascular system, the autonomic nervous system and, most recently, within the central nervous system itself.

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  • (PMID = 17645624.001).
  • [ISSN] 0305-1870
  • [Journal-full-title] Clinical and experimental pharmacology & physiology
  • [ISO-abbreviation] Clin. Exp. Pharmacol. Physiol.
  • [Language] ENG
  • [Grant] None / None / / 50095; Canada / Canadian Institutes of Health Research / / 50095
  • [Publication-type] Journal Article; Review
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Estrogens
  • [Number-of-references] 44
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61. Rocha MP, Campagnolo AM, Macedo VS, Scarton FB, Rocha HP, Kuhl G: Nasal paraganglioma: a case report. Braz J Otorhinolaryngol; 2005 Mar-Apr;71(2):237-40
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  • Paragangliomas are tumors of the autonomic nervous system, arising from paraganglionic tissue.
  • In the head and neck, the most common sites of origin of this neoplasm are the carotid body, the jugular bulb and the vagal body.
  • [MeSH-major] Nose Neoplasms. Paraganglioma

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  • (PMID = 16450456.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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62. Ayala-Ramirez M, Habra MA, Busaidy N, Cote G, Rich T, Waguespack S, Jimenez C: A catecholamine crisis on Mount Kilimanjaro: a hypoxia effect? J Travel Med; 2010 Nov-Dec;17(6):424-6
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  • Sympathetic paragangliomas are autonomic nervous system tumors associated with dysregulation of intracellular oxygen metabolism.
  • Exposure to high altitudes is reported to activate the production of catecholamines in the sympathoadrenal system.
  • [MeSH-major] Anoxia / complications. Heart Atria / pathology. Heart Neoplasms. Normetanephrine / urine. Paraganglioma / complications. Paraganglioma / metabolism
  • [MeSH-minor] Altitude. Bone Neoplasms / secondary. Catecholamines. Fatal Outcome. Humans. Male. Middle Aged. Tanzania. United States

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  • [Copyright] © 2010 International Society of Travel Medicine.
  • (PMID = 21050326.001).
  • [ISSN] 1708-8305
  • [Journal-full-title] Journal of travel medicine
  • [ISO-abbreviation] J Travel Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Catecholamines; 0J45DE6B88 / Normetanephrine
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63. Reusch J, Haag C, Raue F, Badenhoop K: Relapsing pheochromocytoma in a Chinese women caused by a novel mutation in exon 6 of the SDHB gene: a case report. Exp Clin Endocrinol Diabetes; 2007 Oct;115(9):616-8
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  • Pheochromocytomas are rare catecholamine-secreting, chromaffin tumors of the autonomic nervous system.
  • The transabdominal ultrasonography revealed a tumor with reduced echogenicity in the left suprarenal region, which was suspected to be a recurrent pheochromocytoma.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Iron-Sulfur Proteins / genetics. Neoplasm Recurrence, Local / genetics. Pheochromocytoma / genetics. Point Mutation. Succinate Dehydrogenase / genetics
  • [MeSH-minor] Adult. DNA, Neoplasm / chemistry. DNA, Neoplasm / genetics. Female. Humans. Male. Pedigree. Sequence Analysis, DNA

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  • (PMID = 17943698.001).
  • [ISSN] 0947-7349
  • [Journal-full-title] Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • [ISO-abbreviation] Exp. Clin. Endocrinol. Diabetes
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Iron-Sulfur Proteins; EC 1.3.5.1 / SDHB protein, human; EC 1.3.99.1 / Succinate Dehydrogenase
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64. Füessl HS: [One brown eye and one blue eye--bad mood of nature]. MMW Fortschr Med; 2006 Mar 9;148(10):53-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Autonomic Nervous System Diseases / diagnosis. Cervical Vertebrae / surgery. Eye Color. Horner Syndrome / diagnosis. Iris / innervation. Neuroblastoma / surgery. Pigmentation Disorders / etiology. Postoperative Complications / diagnosis. Spinal Neoplasms / surgery
  • [MeSH-minor] Child. Diagnosis, Differential. Functional Laterality. Humans. Male. Sweating / physiology. Sympathetic Nervous System / physiopathology


65. Fonseca IB, Spitale LS, Gramática L, Cejas H, Piccinni DJ, Ghirardi G: [Gastrointestinal stromal tumors: conceptual evolution]. Rev Fac Cien Med Univ Nac Cordoba; 2006;63(1):37-45
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  • Gastrointestinal stromal tumors (GISTs) constitute the largest category of primary nonepithelial neoplasms of the stomach and small bowel.
  • They represent about 1-2% from all neoplasms of the digestive tract.
  • Originally recognized in 1960 by Martin et. al. as a distinctive type of stromal neoplasm of the bowel, they were subsequently reported by Stout, who introduced the term leiomyoblastoma.
  • Because of difficulties in accurately predicting the biologic behavior of these tumors, the term "smooth muscle tumor of uncertain malignant potential" (SMTUMP) has been introduced for borderline tumors.
  • In 1983, Mazur and Clark coined the term gastrointestinal stromal tumor and suggested that these neoplasms might arise from the myenteric nervous system.
  • Some studies have reported evidence of neuronal cell differentiation in a proportion of GISTs and the term "gastrointestinal autonomic nerve tumor (GANT) has been introduced.
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Invasiveness

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  • (PMID = 17639807.001).
  • [ISSN] 0014-6722
  • [Journal-full-title] Revista de la Facultad de Ciencias Médicas (Córdoba, Argentina)
  • [ISO-abbreviation] Rev Fac Cien Med Univ Nac Cordoba
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Argentina
  • [Number-of-references] 46
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66. Madroszkiewicz D, Thor P, Moskała M, Madroszkiewicz E, Gościński I: [Effects of intracranial hypertension on gastric myoelectrical activity evaluated by using clinical and radiological symptoms]. Neurol Neurochir Pol; 2005 Jan-Feb;39(1):41-8
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  • BACKGROUND AND PURPOSE: Acute and chronic increases in intracranial pressure (ICP) cause a dramatic autonomic dysfunction.
  • Gastric myoelectrical activity was captured with cutaneous electrodes and Synectics (Sweden) system of storing and analyzing the data.
  • Gastric dysmotility was caused by stimulation of both arms of the autonomic nervous system.
  • [MeSH-major] Brain Injuries / physiopathology. Brain Neoplasms / physiopathology. Intracranial Hypertension / physiopathology. Myoelectric Complex, Migrating. Stomach / physiopathology

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  • (PMID = 15735989.001).
  • [ISSN] 0028-3843
  • [Journal-full-title] Neurologia i neurochirurgia polska
  • [ISO-abbreviation] Neurol. Neurochir. Pol.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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67. Herbach N, Breuer W, Hermanns W: Metastatic extra-adrenal sympathetic paraganglioma in a horse. J Comp Pathol; 2010 Aug-Oct;143(2-3):199-202
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  • [MeSH-major] Autonomic Nervous System Diseases / veterinary. Horse Diseases / pathology. Paraganglioma, Extra-Adrenal / veterinary. Peritoneal Neoplasms / veterinary. Thyroid Neoplasms / veterinary

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20153870.001).
  • [ISSN] 1532-3129
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chromogranin A; 0 / Nuclear Proteins; 0 / Synaptophysin
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68. Radin D, Stone J, Levine E, Eskandarnejad S, Schlitz M, Kozak L, Mandel D, Hayssen G: Compassionate intention as a therapeutic intervention by partners of cancer patients: effects of distant intention on the patients' autonomic nervous system. Explore (NY); 2008 Jul-Aug;4(4):235-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Compassionate intention as a therapeutic intervention by partners of cancer patients: effects of distant intention on the patients' autonomic nervous system.
  • OBJECTIVE: This double-blind study investigated the effects of intention on the autonomic nervous system of a human "sender" and distant "receiver" of those intentions, and it explored the roles that motivation and training might have in modulating these effects.
  • CONCLUSIONS: Directing intention toward a distant person is correlated with activation of that person's autonomic nervous system.
  • [MeSH-major] Autonomic Nervous System / physiology. Caregivers / psychology. Mental Healing. Neoplasms / psychology. Neoplasms / therapy. Telepathy


69. Lin SC, Chen MF: Increased yin-deficient symptoms and aggravated autonomic nervous system function in patients with metastatic cancer. J Altern Complement Med; 2010 Oct;16(10):1059-63
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  • [Title] Increased yin-deficient symptoms and aggravated autonomic nervous system function in patients with metastatic cancer.
  • OBJECTIVES: The objectives of this study were to investigate the differences in severity of yin-deficiency syndrome (YDS) and function of the autonomic nervous system (ANS) between patients with cancer with metastasis and those without metastasis.
  • ANS function in each subject was evaluated by measuring heart rate variability (HRV), including time and frequency domains.
  • CONCLUSIONS: The results of this study indicate that patients with metastatic cancer have more severe YDS and impaired ANS function than those without metastasis.
  • [MeSH-major] Autonomic Nervous System / physiopathology. Heart Rate. Neoplasm Metastasis / physiopathology. Neoplasms / physiopathology. Yin Deficiency / physiopathology

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  • (PMID = 20874442.001).
  • [ISSN] 1557-7708
  • [Journal-full-title] Journal of alternative and complementary medicine (New York, N.Y.)
  • [ISO-abbreviation] J Altern Complement Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Rob L, Halaska M, Robova H: Nerve-sparing and individually tailored surgery for cervical cancer. Lancet Oncol; 2010 Mar;11(3):292-301
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  • During the past 15 years, substantial progress has been made in understanding the neuroanatomy of the autonomic pelvic plexus.
  • The concept of preservation of autonomic nerves during radical hysterectomy has become standard in many oncogynaecological centres.
  • In this Review, we focus on the neuroanatomy of the pelvis and the possible damage of autonomic nerves, and suggest options for the sparing of these nerves during surgery for cervical cancer.
  • [MeSH-major] Hysterectomy / methods. Nervous System Diseases / prevention & control. Precision Medicine. Uterine Cervical Neoplasms / surgery


71. Gomber S, Dewan P, Chhonker D: Vincristine induced neurotoxicity in cancer patients. Indian J Pediatr; 2010 Jan;77(1):97-100
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  • Autonomic neuropathy presented as constipation and urinary retention in 2 children, while 2 children developed encephalopathy in form of seizures, confusion, aphasia, and transient blindness.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Neoplasms / drug therapy. Peripheral Nervous System Diseases / chemically induced. Vincristine / adverse effects


72. Pawlu C, Bausch B, Reisch N, Neumann HP: Genetic testing for pheochromocytoma-associated syndromes. Ann Endocrinol (Paris); 2005 Jun;66(3):178-85
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  • Pheochromocytoma and paraganglioma are tumors of the autonomic nervous system.
  • Mutational analysis of the susceptibility genes of these syndromes in patients presenting with pheochromocytoma or paraganglioma may help to judge the risks of multifocality of the tumor as well as development of malignant pheochromocytoma or of other malignant tumors.
  • Based on tumor characteristics and prevalence data we give recommendations for an efficient genetic testing procedure in patients presenting with pheochromocytomas and paragangliomas.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Multiple Endocrine Neoplasia Type 2a / genetics. Mutation. Pheochromocytoma / genetics
  • [MeSH-minor] Genes, Neurofibromatosis 1. Humans. Neurofibromatoses / genetics. Oncogene Proteins / genetics. Proto-Oncogene Proteins c-ret. Receptor Protein-Tyrosine Kinases / genetics. Thyroid Neoplasms / genetics. Tumor Suppressor Proteins / genetics. Ubiquitin-Protein Ligases / genetics. Von Hippel-Lindau Tumor Suppressor Protein

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  • (PMID = 15988378.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Oncogene Proteins; 0 / Tumor Suppressor Proteins; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases; EC 6.3.2.19 / Ubiquitin-Protein Ligases; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  • [Number-of-references] 43
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73. Zachariae R, Paulsen K, Mehlsen M, Jensen AB, Johansson A, von der Maase H: Chemotherapy-induced nausea, vomiting, and fatigue--the role of individual differences related to sensory perception and autonomic reactivity. Psychother Psychosom; 2007;76(6):376-84
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  • [Title] Chemotherapy-induced nausea, vomiting, and fatigue--the role of individual differences related to sensory perception and autonomic reactivity.
  • METHODS: Hundred and twenty-five women receiving adjuvant chemotherapy for breast cancer completed measures of absorption, autonomic perception, somatosensory amplification, trait anxiety, and expected severity at baseline.
  • CONCLUSION: Chemotherapy-induced side effects are related to increased autonomic nervous system activity, and absorption has been associated with increased autonomic nervous system reactivity to stress.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Arousal / drug effects. Autonomic Nervous System / drug effects. Awareness / drug effects. Breast Neoplasms / drug therapy. Fatigue / chemically induced. Individuality. Nausea / chemically induced. Sick Role. Somatoform Disorders / diagnosis. Vomiting / chemically induced
  • [MeSH-minor] Adult. Aged. Anxiety / diagnosis. Anxiety / physiopathology. Anxiety / psychology. Biological Availability. Chemotherapy, Adjuvant / adverse effects. Chemotherapy, Adjuvant / psychology. Cyclophosphamide / administration & dosage. Cyclophosphamide / adverse effects. Female. Fluorouracil / administration & dosage. Fluorouracil / adverse effects. Humans. Methotrexate / administration & dosage. Methotrexate / adverse effects. Middle Aged. Personality Inventory. Risk Factors. Sensory Thresholds / drug effects. Sensory Thresholds / physiology. Statistics as Topic

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  • [Copyright] 2007 S. Karger AG, Basel
  • (PMID = 17917474.001).
  • [ISSN] 1423-0348
  • [Journal-full-title] Psychotherapy and psychosomatics
  • [ISO-abbreviation] Psychother Psychosom
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 8N3DW7272P / Cyclophosphamide; U3P01618RT / Fluorouracil; YL5FZ2Y5U1 / Methotrexate; CMF regimen
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74. Asher A, Palmer JL, Yadav RR, Yusuf SW, Konzen B, Bruera E, Guo Y: The effects of a brief relaxation program on symptom distress and heart rate variability in cancer patients. PM R; 2010 Jul;2(7):636-41
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  • OBJECTIVES: To determine whether a 15-minute, one-time guided relaxation program for cancer patients could improve symptom distress as measured by the Edmonton Symptom Assessment System (ESAS).
  • In addition, we were interested in characterizing the changes of the autonomic nervous system, as demonstrated by heart rate variability (HRV) high-frequency (HF) spectral analysis, before and after this relaxation program.
  • [MeSH-major] Heart Rate / physiology. Neoplasms / physiopathology. Neoplasms / psychology. Relaxation Therapy

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  • [Copyright] Copyright © 2010 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20659719.001).
  • [ISSN] 1934-1482
  • [Journal-full-title] PM & R : the journal of injury, function, and rehabilitation
  • [ISO-abbreviation] PM R
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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75. Strzelczyk A, Nowak M, Bauer S, Reif PS, Oertel WH, Knake S, Hamer HM, Rosenow F: Localizing and lateralizing value of ictal flatulence. Epilepsy Behav; 2010 Feb;17(2):278-82
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  • OBJECTIVE: Autonomic seizures have been associated with seizure onset in the temporal or insular lobe and consist of variations in blood pressure and heart rate, sweating, flushing, piloerection, hypersalivation, vomiting, spitting, and alterations in bladder and bowel functions.
  • Our cases and previously reported cases point toward activation of insular cortex because of such additional autonomic symptoms as unilateral piloerection, tachycardia, profound sweating, and flushing of the face.
  • CONCLUSIONS: Ictal flatulence is a rare manifestation of autonomic seizures and a localizing sign for temporal or/and insular lobe epilepsies.
  • [MeSH-minor] Aged. Autonomic Nervous System / physiopathology. Brain Neoplasms / complications. Brain Neoplasms / pathology. Cognition Disorders / complications. Cognition Disorders / diagnosis. Female. Heart Rate / physiology. Humans. Hypertension / complications. Hypertension / diagnosis. Meningioma / complications. Meningioma / pathology. Neuropsychological Tests

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  • [Copyright] (c) 2009 Elsevier Inc. All rights reserved.
  • (PMID = 20064748.001).
  • [ISSN] 1525-5069
  • [Journal-full-title] Epilepsy & behavior : E&B
  • [ISO-abbreviation] Epilepsy Behav
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Gerstner E, Batchelor T: Primary CNS lymphoma. Expert Rev Anticancer Ther; 2007 May;7(5):689-700
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  • Characteristic imaging features should lead to suspicion of the diagnosis, avoidance of corticosteroids (if possible) and early neurosurgical consultation for stereotactic biopsy.
  • Whole-brain radiation therapy alone is insufficient for durable tumor control and is associated with a high risk of neurotoxicity in patients over 60 years of age.
  • Neurotoxicity is typically associated with significant cognitive, motor and autonomic dysfunction and has a negative impact on quality of life.
  • Chemotherapy and whole-brain radiation therapy together improve tumor response rates and survival compared with whole-brain radiation therapy alone.
  • Methotrexate-based multiagent chemotherapy without whole-brain radiation therapy is associated with similar tumor response rates and survival compared with regimens that include whole-brain radiation therapy, although controlled trials have not been performed.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Central Nervous System Neoplasms / drug therapy. Central Nervous System Neoplasms / radiotherapy. Lymphoma, Non-Hodgkin / drug therapy. Lymphoma, Non-Hodgkin / radiotherapy

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  • (PMID = 17492932.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] YL5FZ2Y5U1 / Methotrexate
  • [Number-of-references] 71
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77. Kneist W, Heintz A, Junginger T: Major urinary dysfunction after mesorectal excision for rectal carcinoma. Br J Surg; 2005 Feb;92(2):230-4
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  • BACKGROUND: Urinary dysfunction may occur after mesorectal excision and pelvic autonomic nerve preservation (PANP) in patients with rectal carcinoma.
  • [MeSH-major] Postoperative Complications / etiology. Rectal Neoplasms / surgery. Urination Disorders / etiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Autonomic Nervous System Diseases / etiology. Autonomic Pathways / injuries. Female. Humans. Male. Middle Aged. Prospective Studies. Regression Analysis. Risk Factors. Urinary Catheterization

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  • (PMID = 15609379.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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78. Morita H, Hirota T, Mune T, Suwa T, Ishizuka T, Inuzuka T, Tanaka K, Ishimori M, Nakamura S, Yasuda K: Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma. Am J Med Sci; 2005 Jan;329(1):48-51
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  • A 48-year-old man with autoimmune Addison disease developed the following paraneoplastic neurologic syndromes (PNNS): limbic encephalitis, opsoclonus/myoclonus, and sensorimotor and autonomic neuropathies.
  • [MeSH-major] Addison Disease / etiology. Paraneoplastic Syndromes, Nervous System / etiology. Thymoma / complications. Thymus Neoplasms / complications

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  • (PMID = 15654180.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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79. Paisansathan C, Hoffman WE, Lee M, Ananda RC, Wheeler P: Autonomic activity during desflurane anesthesia in patients with brain tumors. J Clin Monit Comput; 2007 Oct;21(5):265-9
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  • [Title] Autonomic activity during desflurane anesthesia in patients with brain tumors.
  • OBJECTIVE: Although intracranial tumors may affect autonomic function, there are few reports of autonomic changes during anesthesia.
  • The purpose of this study was to evaluate autonomic effects of anesthesia in patients with brain tumors compared to neurosurgical controls.
  • Heart periods were transformed into a percentage index and heart rate entropy determined as a measure of variance of autonomic activity.
  • CONCLUSION: Tone-entropy analysis of heart rate indicates anesthetic related depression of autonomic activity with no difference between groups.
  • Normal titration of desflurane concentrations to maintain adequate blood pressure produced desflurane requirements that were lower in patients with brain tumors, while autonomic and EEG activity were similar.
  • [MeSH-major] Anesthetics, Inhalation / administration & dosage. Autonomic Nervous System / drug effects. Autonomic Nervous System / physiopathology. Brain Neoplasms / physiopathology. Isoflurane / analogs & derivatives

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  • (PMID = 17641979.001).
  • [ISSN] 1387-1307
  • [Journal-full-title] Journal of clinical monitoring and computing
  • [ISO-abbreviation] J Clin Monit Comput
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anesthetics, Inhalation; CRS35BZ94Q / desflurane; CYS9AKD70P / Isoflurane
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80. Breukink SO, Pierie JP, Hoff C, Wiggers T, Meijerink WJ: Technique for laparoscopic autonomic nerve preserving total mesorectal excision. Int J Colorectal Dis; 2006 May;21(4):308-13
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  • [Title] Technique for laparoscopic autonomic nerve preserving total mesorectal excision.
  • The laparoscope seems to facilitate pelvic dissection including identification and preservation of critical structures such as the autonomic nervous system.
  • The technique for laparoscopic autonomic nerve preserving total mesorectal excision is reported.
  • Vascular ligation, sharp mesorectal dissection and identification and preservation of the autonomic pelvic nerves are described.
  • [MeSH-major] Digestive System Surgical Procedures / methods. Laparoscopy / methods. Rectal Neoplasms / surgery
  • [MeSH-minor] Autonomic Pathways. Colostomy. Humans. Rectum / innervation. Rectum / surgery

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  • (PMID = 16059690.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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81. Jiménez-Caballero PE: [Harlequin syndrome secondary to thoracic chondrosarcoma]. Rev Neurol; 2008 Feb 16-29;46(4):252-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Autonomic Nervous System Diseases / etiology. Chondrosarcoma / complications. Face / innervation. Flushing / etiology. Hyperhidrosis / etiology. Lung Neoplasms / complications


82. Laskawi R: [Botulinum toxin treatment in the head and neck region: current aspects, developments, and problems]. HNO; 2007 Jun;55(6):437-42
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  • In addition, treatment of different forms of headache and tinnitus as well as applications in the autonomic nervous system are addressed.
  • [MeSH-major] Autonomic Nervous System Diseases / drug therapy. Botulinum Toxins / therapeutic use. Head. Head and Neck Neoplasms / drug therapy. Headache / drug therapy. Neck. Wound Healing / drug effects

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  • (PMID = 17356873.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 3.4.24.69 / Botulinum Toxins
  • [Number-of-references] 31
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83. Wang JP, Huang MJ, Song XM, Huang YH, Lan P, Cai GF, Zhou J, Tang YZ: [The assessment of curative effect after total mesorectal excision with autonomic nerve preservation for rectal cancer]. Zhonghua Wai Ke Za Zhi; 2005 Dec 1;43(23):1500-2
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  • [Title] [The assessment of curative effect after total mesorectal excision with autonomic nerve preservation for rectal cancer].
  • OBJECTIVE: To evaluate the impact on sexual function, local recurrence and survival after total mesorectal excision (TME) with autonomic nerve preservation (PANP) of rectal cancer.
  • [MeSH-major] Autonomic Nervous System / injuries. Rectal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Follow-Up Studies. Humans. Male. Mesentery / surgery. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Postoperative Complications / prevention & control. Retrospective Studies. Sexual Dysfunction, Physiological / etiology. Sexual Dysfunction, Physiological / prevention & control. Survival Rate. Treatment Outcome

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  • (PMID = 16412282.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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84. Chishima F, Tamura M, Nakazawa T, Sugitani M, Hirano D, Yoshikawa T, Fuchinoue F, Nemoto N, Yamamoto T: Paraaortic paraganglioma arising in an ovarian carcinoma patient mimicking lymph node metastasis. J Obstet Gynaecol Res; 2010 Feb;36(1):204-8
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  • Paragangliomas are rare tumors arising from the chromaffin cells in the autonomic nervous system.
  • Image analysis showed a 21 x 18 x 10 cm ovarian mass, and a 38 mm tumor at the paraaortic lesion.
  • The paraaortic tumor was completely eliminated in spite of fluctuating blood pressure intraoperatively.
  • Microscopic examination revealed that the paraaortic tumor was paraganglioma.
  • [MeSH-major] Cystadenocarcinoma / diagnosis. Endocrine Gland Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Ovarian Neoplasms / diagnosis. Para-Aortic Bodies. Paraganglioma / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Lymphatic Metastasis / diagnosis. Middle Aged

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  • (PMID = 20178553.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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85. Guasti L, Marino F, Cosentino M, Cimpanelli M, Piantanida E, Mainardi LT, Vanoli P, De Palma D, Bombelli R, Ferrari M, Crespi C, Simoni C, Klersy C, Gaudio G, Maroni L, Grandi AM, Tanda M, Bartalena L, Cerutti S, Lecchini S, Venco A: Changes in autonomic modulation to the heart and intracellular catecholamines. A longitudinal study in differentiated thyroid carcinoma during short-term hypothyroidism and thyroid hormone replacement. Horm Res; 2007;67(4):171-8
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  • [Title] Changes in autonomic modulation to the heart and intracellular catecholamines. A longitudinal study in differentiated thyroid carcinoma during short-term hypothyroidism and thyroid hormone replacement.
  • BACKGROUND: The effects of thyroid deprivation on the autonomic modulation to the heart remain controversial.
  • [MeSH-minor] Autonomic Nervous System / drug effects. Autonomic Nervous System / physiology. Baroreflex / drug effects. Baroreflex / physiology. Blood Pressure / drug effects. Blood Pressure / physiology. Carcinoma, Papillary / radionuclide imaging. Carcinoma, Papillary / radiotherapy. Carcinoma, Papillary / surgery. Cells, Cultured. Dopamine / urine. Epinephrine / urine. Humans. Lymphocytes / cytology. Lymphocytes / metabolism. Norepinephrine / urine. Sinoatrial Node / drug effects. Sinoatrial Node / physiology. Thyroid Neoplasms / radionuclide imaging. Thyroid Neoplasms / radiotherapy. Thyroid Neoplasms / surgery. Thyroidectomy. Whole Body Imaging

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  • (PMID = 17106203.001).
  • [ISSN] 0301-0163
  • [Journal-full-title] Hormone research
  • [ISO-abbreviation] Horm. Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Catecholamines; 0 / Thyroid Hormones; VTD58H1Z2X / Dopamine; X4W3ENH1CV / Norepinephrine; YKH834O4BH / Epinephrine
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86. Tan KM, Lennon VA, Klein CJ, Boeve BF, Pittock SJ: Clinical spectrum of voltage-gated potassium channel autoimmunity. Neurology; 2008 May 13;70(20):1883-90
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  • Neoplasms encountered (confirmed histologically in 33%) included 18 carcinomas, 5 adenomas, 1 thymoma, and 3 hematologic malignancies.
  • CONCLUSIONS: The spectrum of neurologic manifestations and neoplasms associated with voltage-gated potassium channel (VGKC) autoimmunity is broader than previously recognized.
  • [MeSH-major] Autoantibodies / blood. Paraneoplastic Syndromes / immunology. Peripheral Nervous System Diseases / immunology. Shaker Superfamily of Potassium Channels / immunology
  • [MeSH-minor] Adenoma / complications. Adolescent. Adult. Aged. Aged, 80 and over. Autonomic Nervous System Diseases / etiology. Autonomic Nervous System Diseases / immunology. Basal Ganglia Diseases / etiology. Basal Ganglia Diseases / immunology. Child. Cranial Nerve Diseases / etiology. Cranial Nerve Diseases / immunology. Female. Fluorescent Antibody Technique, Indirect. Hematologic Neoplasms / complications. Humans. Kv1.1 Potassium Channel / immunology. Kv1.2 Potassium Channel / immunology. Male. Middle Aged. Myoclonus / etiology. Myoclonus / immunology. Thymoma / complications. Thymus Neoplasms / complications

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  • [CommentIn] Neurology. 2009 Jan 6;72(1):99; author reply 99-100 [19122041.001]
  • (PMID = 18474843.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / KCNA6 protein, human; 0 / Kv1.2 Potassium Channel; 0 / Shaker Superfamily of Potassium Channels; 147173-20-4 / Kv1.1 Potassium Channel
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87. Chiang JK, Koo M, Kuo TB, Fu CH: Association between cardiovascular autonomic functions and time to death in patients with terminal hepatocellular carcinoma. J Pain Symptom Manage; 2010 Apr;39(4):673-9
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  • [Title] Association between cardiovascular autonomic functions and time to death in patients with terminal hepatocellular carcinoma.
  • OBJECTIVE: To explore the association of cardiovascular autonomic functions with TTD in patients with terminal hepatocellular carcinoma.
  • Cardiovascular autonomic functions were evaluated by frequency-domain measures of heart rate variability (HRV) on admission.
  • CONCLUSION: This is the first study to evaluate the association between cardiovascular autonomic functions and TTD in patients with terminal hepatocellular carcinoma.
  • [MeSH-major] Autonomic Nervous System Diseases / mortality. Carcinoma, Hepatocellular / mortality. Death, Sudden, Cardiac / epidemiology. Electrocardiography / statistics & numerical data. Life Expectancy. Liver Neoplasms / diagnosis

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  • [Copyright] Copyright (c) 2010 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20413055.001).
  • [ISSN] 1873-6513
  • [Journal-full-title] Journal of pain and symptom management
  • [ISO-abbreviation] J Pain Symptom Manage
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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88. Todo Y, Kuwabara M, Watari H, Ebina Y, Takeda M, Kudo M, Yamamoto R, Sakuragi N: Urodynamic study on postsurgical bladder function in cervical cancer treated with systematic nerve-sparing radical hysterectomy. Int J Gynecol Cancer; 2006 Jan-Feb;16(1):369-75
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  • Of the 27 patients, autonomic nerves had been completely preserved at least on one side in 22 patients (group A), and autonomic nerves could not be successfully preserved in five patients (group B).
  • [MeSH-major] Hysterectomy / adverse effects. Urination Disorders / diagnosis. Uterine Cervical Neoplasms / surgery. Uterus / innervation
  • [MeSH-minor] Adult. Analysis of Variance. Autonomic Nervous System / physiology. Cohort Studies. Female. Follow-Up Studies. Humans. Middle Aged. Neoplasm Staging. Postoperative Care. Postoperative Complications / diagnosis. Preoperative Care. Probability. Risk Assessment. Sensitivity and Specificity. Statistics, Nonparametric. Treatment Outcome. Urodynamics


89. Campellone JV, Hageboutros A: Adie's pupils in paraneoplastic ganglionopathy with ANNA-1. Clin Neurol Neurosurg; 2006 Oct;108(7):712-4
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  • Autonomic disturbances are common in patients with paraneoplastic syndromes associated with type-1 antineuronal nuclear autoantibodies (ANNA-1), although pupillary disturbances are infrequent.
  • [MeSH-major] Antibodies, Neoplasm / immunology. Autonomic Nervous System Diseases / physiopathology. Carcinoma, Small Cell / complications. Lung Neoplasms / complications. Paraneoplastic Syndromes, Nervous System / physiopathology. Tonic Pupil / physiopathology
  • [MeSH-minor] Aged. Azathioprine / therapeutic use. Gait Disorders, Neurologic / diagnosis. Gait Disorders, Neurologic / immunology. Gait Disorders, Neurologic / physiopathology. Ganglia, Parasympathetic / immunology. Ganglia, Parasympathetic / pathology. Ganglia, Parasympathetic / physiopathology. Humans. Immunosuppressive Agents / therapeutic use. Iris / innervation. Iris / physiopathology. Male. Oculomotor Nerve / immunology. Oculomotor Nerve / pathology. Oculomotor Nerve / physiopathology. Oculomotor Nerve Diseases / diagnosis. Oculomotor Nerve Diseases / immunology. Oculomotor Nerve Diseases / physiopathology. Peripheral Nervous System Diseases / diagnosis. Peripheral Nervous System Diseases / immunology. Peripheral Nervous System Diseases / physiopathology. Pupil. Sensation Disorders / diagnosis. Sensation Disorders / immunology. Sensation Disorders / physiopathology. Treatment Outcome

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  • (PMID = 16139419.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Immunosuppressive Agents; MRK240IY2L / Azathioprine
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90. Tomita R, Igarashi S, Fujisaki S, Koshinaga T, Kusafuka T: Are there any functional differences of enteric nervous system between the proximal and distal parts from the dentate line in the normal human internal anal sphincter? Hepatogastroenterology; 2008 Nov-Dec;55(88):2083-6
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  • [Title] Are there any functional differences of enteric nervous system between the proximal and distal parts from the dentate line in the normal human internal anal sphincter?
  • BACKGROUND/AIMS: To clarify the functional differences of the enteric nervous system in the human internal anal sphincter (IAS) between the proximal and distal parts from the dentate line, we investigated the enteric nerve responses of normal proximal and distal IAS in vitro.
  • A mechanographic technique was used to evaluate in vitro muscle strip responses to electrical field stimulation (EFS) before and after treatment with various autonomic nerve blockers. RESULTS:.
  • CONCLUSIONS: There are functional differences in the regulation of the enteric nervous system between the PIAS and DIAS.
  • [MeSH-major] Anal Canal / innervation. Enteric Nervous System / physiopathology
  • [MeSH-minor] Aged. Anesthetics, Local / pharmacology. Electric Stimulation. Female. Humans. In Vitro Techniques. Male. Middle Aged. Muscle Contraction / physiology. Rectal Neoplasms. Tetrodotoxin / pharmacology

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  • (PMID = 19260481.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Anesthetics, Local; 4368-28-9 / Tetrodotoxin
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91. Iizuka T: [Clinical features and pathogenesis of anti-NMDA receptor encephalitis]. Rinsho Shinkeigaku; 2008 Nov;48(11):920-2
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  • Most cases developed seizures, followed by unresponsive/catatonic state, decreased level of consciousness, central hypoventilation, orofacial-limb dyskinesias, and autonomic symptoms.
  • [MeSH-major] Autoantibodies. Encephalitis. Paraneoplastic Syndromes, Nervous System. Receptors, N-Methyl-D-Aspartate / immunology
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Dyskinesias / etiology. Female. Humans. Japan / epidemiology. Male. Middle Aged. Ovarian Neoplasms. Schizophrenia / etiology. Sleep Apnea, Central / etiology. Teratoma. Young Adult

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  • (PMID = 19198118.001).
  • [ISSN] 0009-918X
  • [Journal-full-title] Rinshō shinkeigaku = Clinical neurology
  • [ISO-abbreviation] Rinsho Shinkeigaku
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Receptors, N-Methyl-D-Aspartate
  • [Number-of-references] 10
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92. Liang JT, Lai HS, Lee PH, Chang KJ: Laparoscopic pelvic autonomic nerve-preserving surgery for sigmoid colon cancer. Ann Surg Oncol; 2008 Jun;15(6):1609-16
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  • [Title] Laparoscopic pelvic autonomic nerve-preserving surgery for sigmoid colon cancer.
  • BACKGROUND: To test the feasibility of laparoscopic approach in performing the simultaneous pelvic autonomic nerve preservation during standard anterior resection of sigmoid colon cancer.
  • RESULTS: A total of 112 patients (tumor, node, metastasis system stage I, n = 8; stage II, n = 54; stage III, n = 50; male, n = 58; female, n = 54; age [mean +/- standard deviation], 55.8 +/- 6.4 years) with good baseline genitourinary function were operated on with the intent of total preservation of pelvic autonomic nerves and curative resection of sigmoid colon cancer.
  • CONCLUSIONS: Under laparoscopy, we can clearly identify and preserve the pelvic autonomic nerves to retain genitourinary function in most patients undergoing oncologic resection of sigmoid colon cancer.
  • [MeSH-major] Adenocarcinoma / surgery. Autonomic Pathways / surgery. Colectomy. Sigmoid Neoplasms / surgery. Trauma, Nervous System / prevention & control

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  • (PMID = 18365285.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2373867
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93. Harb A, Forster J, Damjanov I: Gastrointestinal autonomic nerve tumor secreting catecholamines. Virchows Arch; 2005 Nov;447(5):892-3
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  • [Title] Gastrointestinal autonomic nerve tumor secreting catecholamines.
  • [MeSH-major] Autonomic Nervous System Diseases / pathology. Catecholamines / secretion. Gastrointestinal Neoplasms / pathology. Neoplasms, Nerve Tissue / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cytoplasmic Granules / metabolism. Cytoplasmic Granules / ultrastructure. Humans. Male. Middle Aged. Neurosecretory Systems / metabolism. Neurosecretory Systems / pathology. Proto-Oncogene Proteins c-kit / metabolism. Secretory Vesicles / ultrastructure. Treatment Outcome

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  • [Cites] Am J Surg Pathol. 2001 Aug;25(8):979-87 [11474281.001]
  • [Cites] Hum Pathol. 2002 May;33(5):459-65 [12094370.001]
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  • (PMID = 16021513.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Catecholamines; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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94. Tomita R, Igarashi S, Fujisaki S, Tanjoh K: The effects of neurotensin in the colon of patients with slow transit constipation. Hepatogastroenterology; 2007 Sep;54(78):1662-6
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  • A mechanographic technique was used to evaluate in vitro muscle responses to electrical field stimulation (EFS) before and after treatment with various autonomic nerve blockers and NT.
  • [MeSH-minor] Adult. Aged. Colonic Neoplasms / metabolism. Colonic Neoplasms / surgery. Electrophysiology. Enteric Nervous System / metabolism. Female. Humans. Intestinal Mucosa / pathology. Male. Middle Aged. Receptors, Adrenergic / metabolism. Receptors, Cholinergic / metabolism

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  • (PMID = 18019689.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Receptors, Adrenergic; 0 / Receptors, Cholinergic; 39379-15-2 / Neurotensin
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95. Liang JT, Lai HS, Lee PH: Laparoscopic pelvic autonomic nerve-preserving surgery for patients with lower rectal cancer after chemoradiation therapy. Ann Surg Oncol; 2007 Apr;14(4):1285-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic pelvic autonomic nerve-preserving surgery for patients with lower rectal cancer after chemoradiation therapy.
  • OBJECTIVE: This is a phase II study, the aim of which is to determine if a laparoscopic approach can be used in pelvic autonomic nerve-preserving surgery for patients with lower rectal cancer following chemoradiation therapy.
  • METHODS: Patients with T3 lower rectal cancer treated by preoperative chemoradiation were recruited and subjected to laparoscopic pelvic autonomic nerve-preserving surgery with total mesorectal excision and a sphincter-saving procedure.
  • Postoperatively, only patients successfully operated on by total pelvic autonomic nerve-preserving surgery were included in the statistical analysis of surgical outcomes.
  • The reason for these four parameters is because the influence of pelvic autonomic nerve damage on female sexual function has been ambiguous but would most likely result in impairment of vaginal lubrication and congestion of the genitals.
  • With respect to scrutiny of surgical specimens, the distal safety margin was adequate (mean: 2.4 cm; range: 1.2-5.6 cm), and the circumferential resection margins were free of tumor invasion (mean: 8.6 mm; range: 2-18 mm).
  • CONCLUSIONS: By the laparoscopic approach, total preservation of pelvic autonomic nerves without compromise of the radical extirpation of tumor is technically feasible in the vast majority of patients with lower rectal cancer who have undergone concurrent chemoradiation therapy, thus facilitating the retention of genitourinary function in a significant proportion of such patients.
  • [MeSH-major] Autonomic Nervous System / physiology. Laparoscopy. Neurosurgical Procedures. Pelvis / innervation. Postoperative Complications / prevention & control. Rectal Neoplasms / surgery
  • [MeSH-minor] Combined Modality Therapy. Female. Humans. Male. Neoplasm Staging. Treatment Outcome

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  • (PMID = 17235719.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
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96. Vorob'ev GI, Tsar'kov PV, Podmarenkova LF, Troitskiĭ AA, Aleshin DV: [Nerve-preserving operations in surgery of rectal cancer]. Khirurgiia (Mosk); 2005;(8):22-8
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  • Three groups were divided depending on types of this surgery: 1-- complete preservation of elements of autonomic nervous system (n=31), 2 -- partial preservation (n=16), 3 -- complete ablation (n=1).
  • [MeSH-major] Adenocarcinoma / surgery. Rectal Neoplasms / surgery. Rectum / innervation. Salvage Therapy / methods. Sciatic Nerve / physiology

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  • (PMID = 16091676.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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97. van Vuurden DG, Plötz FB, de Jong M, Bokenkamp A, van Wijk JA: Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome. Pediatr Nephrol; 2005 Nov;20(11):1655-6
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  • A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction.
  • [MeSH-major] ELAV Proteins / immunology. Neuroblastoma / immunology. Paraneoplastic Syndromes, Nervous System / therapy. Plasma Exchange. Spinal Cord Neoplasms / immunology

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  • (PMID = 16133055.001).
  • [ISSN] 0931-041X
  • [Journal-full-title] Pediatric nephrology (Berlin, Germany)
  • [ISO-abbreviation] Pediatr. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / ELAV Proteins
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98. Faria J, Valente V, Lima P, Silva JA, Polónia J: Paraganglioma--a case of secondary hypertension. Rev Port Cardiol; 2010 Oct;29(10):1583-9
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  • Paragangliomas (extra-adrenal pheochromocytomas) are rare tumors originating in the autonomic nervous system, whose clinical manifestations are the result of excessive production of catecholamines.
  • The classic triad of palpitations, headache, and diaphoresis associated with hypertension (HT), elevated serum and urine catecholamine levels, and visualization of the mass on imaging tests, enables diagnosis of these tumors, which are mostly benign, and if diagnosed and treated early, are a potentially treatable cause of secondary hypertension.
  • The mass was excised by laparotomy and the diagnosis of paraganglioma was confirmed.
  • [MeSH-major] Hypertension / etiology. Paraganglioma / complications. Retroperitoneal Neoplasms / complications

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  • (PMID = 21265497.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Portugal
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99. Misawa T, Mizusawa H: [Anti-VGKC antibody-associated limbic encephalitis/Morvan syndrome]. Brain Nerve; 2010 Apr;62(4):339-45
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  • Anti-voltage-gated potassium channel antibodies (anti-VGKC-Ab) cause hyperexcitability of the peripheral nerve and central nervous system.
  • Morvan syndrome is characterized by neuromyotonia with autonomic and CNS involvement.
  • Morvan syndrome is characterized by widespread neurological symptoms involving the peripheral nervous system (neuromyotonia), autonomic system (hyperhidrosis, severe constipation, urinary incontinence, and cardiac arrhythmia) and the CNS (severe insomnia, hallucinations, impairment of short-term memory and epilepsy).
  • Many patients have an underlying tumor, for example thymoma, lung cancer, testicular cancer and lymphoma; this indicates the paraneoplastic nature of the disease.
  • Plasma exchange is an effective treatment approach, and tumor resection also improves symptoms.
  • [MeSH-minor] Adrenal Cortex Hormones / administration & dosage. Female. Humans. Immunoglobulins, Intravenous / administration & dosage. Middle Aged. Neoplasms / complications. Plasma Exchange

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  • (PMID = 20420173.001).
  • [ISSN] 1881-6096
  • [Journal-full-title] Brain and nerve = Shinkei kenkyū no shinpo
  • [ISO-abbreviation] Brain Nerve
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Autoantibodies; 0 / Immunoglobulins, Intravenous; 0 / Potassium Channels, Voltage-Gated
  • [Number-of-references] 36
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100. Sevilla MA, Hermsen MA, Weiss MM, Grimbergen A, Balbín M, Llorente JL, Rodrigo JP, Suárez C: Chromosomal changes in sporadic and familial head and neck paragangliomas. Otolaryngol Head Neck Surg; 2009 May;140(5):724-9
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  • OBJECTIVE: Paragangliomas (PGLs) of the head and neck are benign neoplasms derived from the autonomic nervous system.
  • [MeSH-major] Head and Neck Neoplasms / genetics. Paraganglioma / genetics. Succinate Dehydrogenase / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Chi-Square Distribution. Comparative Genomic Hybridization. DNA Mutational Analysis. Female. Germ-Line Mutation. Humans. Male. Middle Aged. Proto-Oncogene Proteins c-ret / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 19393419.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.3.99.1 / Succinate Dehydrogenase; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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