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81. Viswanatha B: Kimura's disease in children: a 9 years prospective study. Int J Pediatr Otorhinolaryngol; 2007 Oct;71(10):1521-5
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  • [Title] Kimura's disease in children: a 9 years prospective study.
  • Kimura's disease is a rare form of chronic inflammatory disorder involving subcutaneous tissue, predominantly in the head and neck region and frequently associated with lymphadenopathy and/or salivary gland enlargement.
  • The nodular lesions are deep seated in subcutaneous tissue and clinically may mimic a neoplasm.
  • Hence head and neck surgeons need to be aware of clinical presentation of Kimura's disease.
  • OBJECTIVES: To study the clinical presentations, management and complications of Kimura's disease in pediatric age group.
  • RESULTS: All the patients presented with painless swelling in the head and neck region.
  • Post-auricular region was the commonest site (50%).
  • One patient had nephrotic syndrome (5.5%).
  • CONCLUSION: Post-auricular region is the commonest site of involvement.
  • The only systemic complication is nephrotic syndrome.

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  • (PMID = 17586058.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 37341-29-0 / Immunoglobulin E
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82. Turgut G, Sacak B, Kiran K, Bas L: Use of rapid prototyping in prosthetic auricular restoration. J Craniofac Surg; 2009 Mar;20(2):321-5
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  • [Title] Use of rapid prototyping in prosthetic auricular restoration.
  • Reconstructing auricular defects is a challenging task for facial reconstructive surgeons.
  • Auricular restorations with facial prosthesis have produced promising results, but there are still problems to be tackled for improved results.
  • Rapid prototyping in the production of an auricular prosthesis uses the mirror image of contralateral ear and produces excellent forms, eliminating the subjective perception of the prosthodontist.
  • Between 2004 and 2007, 10 patients applied to our department with the absence of an ear on a single side.
  • The etiology for the loss of the ear was mostly tumors, followed by congenital deformities and trauma, respectively.
  • [MeSH-major] Computer-Aided Design. Ear, External. Prostheses and Implants. Prosthesis Design
  • [MeSH-minor] Burns / surgery. Child. Ear Neoplasms / rehabilitation. Ear Neoplasms / surgery. Humans. Image Processing, Computer-Assisted. Longitudinal Studies. Magnetic Resonance Imaging. Male. Middle Aged. Osseointegration / physiology. Prosthesis Coloring. Prosthesis Implantation. Tomography, X-Ray Computed. User-Computer Interface. Young Adult

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  • (PMID = 19276832.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Meningaud JP, Bertolus C, Bertrand JC: Parotidectomy: assessment of a surgical technique including facelift incision and SMAS advancement. J Craniomaxillofac Surg; 2006 Jan;34(1):34-7
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  • [Title] Parotidectomy: assessment of a surgical technique including facelift incision and SMAS advancement.
  • In both procedures the posterior branch of the great auricular nerve was not preserved, hence the two procedures were not evaluated regarding sensitivity of the auricle and preauricular area.
  • RESULT: Before parotidectomy, patients were concerned in a decreasing order with the facial nerve function, the scar, the soft-tissue defect in the dorsal part of the cheek and Frey's syndrome.
  • Following use of the classical technique, patients were concerned in decreasing order with the soft-tissue defect, the scar and Frey's syndrome.
  • Following the SMAS technique, no one was concerned with the scar, Frey's syndrome, or the soft tissue defect although a slight asymmetry could still be noticed.
  • CONCLUSION: The SMAS-lifting technique might possibly appear to offer a new standard procedure for parotidectomy, except for malignant tumours or in obese patients.
  • [MeSH-minor] Adult. Aged. Attitude to Health. Cheek / pathology. Cicatrix / etiology. Cicatrix / psychology. Ear, External / innervation. Facial Nerve / physiology. Fascia / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neck Muscles / surgery. Patient Satisfaction. Rhytidoplasty. Sensation / physiology. Surgical Flaps. Sweating, Gustatory / etiology. Sweating, Gustatory / psychology. Treatment Outcome

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  • (PMID = 16343918.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Scotland
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4. Li G, Chang S, Adler JR Jr, Lim M: Irradiation of glomus jugulare tumors: a historical perspective. Neurosurg Focus; 2007;23(6):E13
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  • [Title] Irradiation of glomus jugulare tumors: a historical perspective.
  • Glomus jugulare tumors are rare, slow-growing vascular lesions that arise from the chief cells of the paraganglia within the jugular bulb.
  • They can be associated with the tympanic branch of the glossopharyngeal nerve (Jacobsen nerve) or the auricular branch of the vagus nerve (Arnold nerve) and are also referred to as chemodectomas or nonchromaffin paragangliomas.
  • Optimal treatment of these histologically benign tumors remains controversial.
  • External-beam radiation was originally used for subtotal resections and in patients who were poor surgical candidates; however, radiosurgery has recently been introduced as an effective and safe treatment option for patients with these tumors.
  • In this article the authors discuss the history of radiation therapy for glomus jugulare tumors, focusing on recent radiosurgical results.
  • [MeSH-major] Glomus Jugulare Tumor / radiotherapy. Glomus Jugulare Tumor / surgery. Radiosurgery / history. Radiosurgery / methods

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  • (PMID = 18081478.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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85. Brozek K, Kozakiewicz J, Kierzek A: [Professor Wacław Kuśnierczyk (1908-1997)--Pro Memoria in the century of birthday]. Otolaryngol Pol; 2009 Mar-Apr;63(2):215-8
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  • In 1953 he obtained the title of second degree specialist in ear, nose and throat diseases.
  • Since then this eminent physician was working on tumours located in upper respiratory tract and the possibility of its endoscopic diagnosis at Silesian Academy of Medicine in Katowice.
  • It was Wacław Kuśnierczyk who implemented new priorities for integrated programs in patient care, research, education and cancer prevention.

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  • (PMID = 19681499.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Biography; English Abstract; Historical Article; Journal Article; Portraits
  • [Publication-country] Poland
  • [Personal-name-as-subject] Kuśnierczyk W
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86. García-Quintana A, Martín-Lorenzo P, Suárez de Lezo J, Díaz-Escofet M, Llorens R, Medina A: [Infected left atrial myxoma]. Rev Esp Cardiol; 2005 Nov;58(11):1358-60
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  • [Transliterated title] Mixoma auricular izquierdo infectado.
  • Myxoma is the most common primary tumor of the heart.
  • It is uncommon for these tumors to become infected and, at times, clinical presentation is no different from that of an uninfected myxoma.
  • We describe the case of a 58-year-old woman with a previous pharyngeal infection that developed into infection of a left atrial myxoma and which was complicated by systemic embolism affecting the lower limbs.
  • The tumor was resected and the patient's subsequent clinical evolution was uneventful.
  • [MeSH-major] Heart Neoplasms / complications. Myxoma / complications. Streptococcal Infections / complications. Streptococcus oralis

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  • (PMID = 16324591.001).
  • [ISSN] 0300-8932
  • [Journal-full-title] Revista española de cardiología
  • [ISO-abbreviation] Rev Esp Cardiol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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87. Khafif A: [Recurrent pleomorphic adenoma of the parotid gland]. Harefuah; 2007 Feb;146(2):111-2, 165
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  • Resection of such recurrences is associated with an increased risk of facial nerve injury and a higher incidence of recurrent disease.
  • Resection of the primary tumor with a cuff of normal tissue around it during the primary surgical resection lowers the incidence of such metastases, but even with them, metastases still occur.
  • Intraoperative monitoring of the facial nerve may be of help during these surgical interventions, but the surgeon need not rely on the monitor only, but identify the nerve based on its well known anatomy and use the monitor as another surgical tool for safe removal of the tumor.
  • In these cases, the nerve should be reconstructed with a cable graft (mainly greater auricular or sural) when possible.
  • Radiotherapy is reserved for patients that had multiple recurrences or had massive tumor spillage during their surgical procedure of the recurrent tumor.
  • [MeSH-major] Adenoma / pathology. Adenoma / surgery. Parotid Neoplasms / pathology. Parotid Neoplasms / surgery
  • [MeSH-minor] Humans. Neoplasm Metastasis. Recurrence

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  • (PMID = 17352279.001).
  • [ISSN] 0017-7768
  • [Journal-full-title] Harefuah
  • [ISO-abbreviation] Harefuah
  • [Language] heb
  • [Publication-type] Editorial; English Abstract
  • [Publication-country] Israel
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88. Zhang B, Huang HZ, Pan CB, Wang JG, Chen WL, Yang ZH: [Effect analysis of modified radical surgery in tongue cancer at early stages]. Zhonghua Yi Xue Za Zhi; 2007 Sep 25;87(36):2578-80
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  • METHODS: Six patients with early stage squamous cell carcinoma of tongue underwent a procedure of modified radical surgery, in which an inconspicuous incision was used, the external jugular vein, sternocleidomastoid muscle, spino-accessory nerve, and greater auricular nerve were preserved, half of glosso and mouth floor were excised, and the defect was repaired instantly.
  • RESULTS: Compared with classic radical neck dissection, this procedure of modified radical surgery showed an inconspicuous incision and pretty appearance, minor edema on face and neck, better shoulder function, and sensation of auricular skin.
  • The patients showed better oncological safety, pretty appearance of tongue, and better oral function of speech, swallow and mastication.
  • CONCLUSION: This ideal procedure of modified radical surgery in tongue cancer at early stages lessens or avoids destruction of face and neck, shoulder malfunction, numbness of auricular skin, and oral dysfunction of speech, swallow and mastication without impairment on the oncologic safety of the radical surgery, and improves the quality of life of the patients.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Neck / surgery. Neck Dissection / methods. Tongue Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Male. Neoplasm Staging. Treatment Outcome

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  • (PMID = 18067839.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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89. Roh JL, Kim HS, Park CI: Randomized clinical trial comparing partial parotidectomy versus superficial or total parotidectomy. Br J Surg; 2007 Sep;94(9):1081-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: In recent decades the treatment of benign parotid tumours has shifted from superficial or total parotidectomy to partial parotidectomy.
  • This study examined whether current surgical techniques improved functional outcomes after surgery for benign parotid tumours.
  • The latter consisted of modified facelift incision, greater auricular nerve preservation, partial parotidectomy and coverage with parotid fascia.
  • RESULTS: The mean duration of operation was 0.7 h shorter and the overall complication rate significantly lower in the functional surgery group.
  • In this group, more patients were satisfied with their scars and facial contours, the auricular nerve sensory recovery rate was high, and transient facial paralysis and Frey's syndrome were infrequent (12 and 6 per cent respectively).
  • There was no tumour recurrence in either group during a mean follow-up of 48 months.
  • CONCLUSION: Compared with conventional procedures, function-preserving surgery for benign parotid tumours improved cosmetic, sensory and salivary functions, and reduced the duration of surgery and operative morbidity.
  • [MeSH-major] Otorhinolaryngologic Surgical Procedures / methods. Parotid Gland / surgery. Parotid Neoplasms / surgery. Patient Satisfaction. Postoperative Complications / prevention & control

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  • [Copyright] Copyright (c) 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
  • (PMID = 17701949.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] England
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90. Butman JA, Kim HJ, Baggenstos M, Ammerman JM, Dambrosia J, Patsalides A, Patronas NJ, Oldfield EH, Lonser RR: Mechanisms of morbid hearing loss associated with tumors of the endolymphatic sac in von Hippel-Lindau disease. JAMA; 2007 Jul 4;298(1):41-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mechanisms of morbid hearing loss associated with tumors of the endolymphatic sac in von Hippel-Lindau disease.
  • CONTEXT: Endolymphatic sac tumors (ELSTs) are associated with von Hippel-Lindau disease and cause irreversible sensorineural hearing loss (SNHL) and vestibulopathy.
  • DESIGN, SETTING, AND PATIENTS: Prospective and serial evaluation of patients with von Hippel-Lindau disease and ELSTs at the National Institutes of Health between May 1990 and December 2006.
  • MAIN OUTCOME MEASURES: Clinical findings and audiologic data were correlated with serial magnetic resonance imaging and computed tomography imaging studies to determine mechanisms underlying audiovestibular dysfunction.
  • RESULTS: Thirty-five patients with von Hippel-Lindau disease and ELSTs in 38 ears (3 bilateral ELSTs) were identified.
  • Tumor invasion of the otic capsule was associated with larger tumors (P = .01) and occurred in 7 ears (18%) causing SNHL (100%).
  • No evidence of otic capsule invasion was present in the remaining 31 ears (82%).
  • Tumor size was not related to SNHL (P = .23) or vestibulopathy (P = .83).
  • CONCLUSIONS: ELST-associated SNHL and vestibulopathy may occur suddenly due to tumor-associated intralabyrinthine hemorrhage, or insidiously, consistent with endolymphatic hydrops.
  • Both of these pathophysiologic mechanisms occur with small tumors that are not associated with otic capsule invasion.

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  • [CommentIn] Arch Otolaryngol Head Neck Surg. 2007 Sep;133(9):857 [17875849.001]
  • (PMID = 17609489.001).
  • [ISSN] 1538-3598
  • [Journal-full-title] JAMA
  • [ISO-abbreviation] JAMA
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
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91. Cai Z, Jiang H, Guo D: [Reconstruction of contracted eye socket using expanded forehead island skin flap]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2007 Aug;21(8):847-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The defects were caused by tumors in 2 patients, by trauma in 3, and by chemical burns in 1; the defects were in the left eyes of 4 patients and in the right eyes of the remaining 2 patients, with the illness course of 1 year to 4 years.
  • RESULTS: The follow-up of all the patients for 1-3 years revealed that the skin flaps survived, with no visible contracture, and the fine sensory function was still present.
  • CONCLUSION: Reconstruction of the eye socket with an expanded forehead island skin flap with the supratrochlear and supraorbital arteries is a feasible, effective and simply method, and the patient can have a concealed incision, a satisfactory appearance, and a fine sensory function.
  • [MeSH-minor] Adolescent. Adult. Eye Neoplasms / surgery. Feasibility Studies. Female. Follow-Up Studies. Graft Survival. Humans. Male. Treatment Outcome. Young Adult

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  • (PMID = 17882882.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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92. Devaney KO, Boschman CR, Willard SC, Ferlito A, Rinaldo A: Tumours of the external ear and temporal bone. Lancet Oncol; 2005 Jun;6(6):411-20
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  • [Title] Tumours of the external ear and temporal bone.
  • Symptoms such as hearing impairment, tinnitus, or a disturbance in sense of balance can generally be attributed to non-neoplastic causes, such as otitis media, otosclerosis, or trauma.
  • Less commonly, auricular signs and symptoms are the result of non-neoplastic and neoplastic space-occupying lesions.
  • The external ear can be the site of development of squamous carcinomas and basal-cell carcinomas; the middle ear and inner ear can host metastatic deposits, and primary squamous carcinomas and adenocarcinomas.
  • Most auricular malignant diseases occur in adulthood; only the rhabdomyosarcomas of the middle ear arise in children.
  • Most malignant diseases of the auricular apparatus are treated by a combination of surgery (commonly including radical excision of temporal bone), radiotherapy, and chemotherapy.
  • [MeSH-major] Ear Neoplasms / diagnosis. Ear Neoplasms / therapy. Ear, External. Skull Neoplasms / diagnosis. Skull Neoplasms / therapy. Temporal Bone

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  • (PMID = 15925819.001).
  • [ISSN] 1470-2045
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 76
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93. Patel AK, Alexander TH, Andalibi A, Ryan AF, Doherty JK: Vestibular schwannoma quantitative polymerase chain reaction expression of estrogen and progesterone receptors. Laryngoscope; 2008 Aug;118(8):1458-63
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  • OBJECTIVES/HYPOTHESIS: Determine the role of estrogen receptor (ER) and progesterone receptor (PR) expression in sporadic and neurofibromatosis 2 (NF2)-related vestibular schwannomas (VS).
  • Growth and proliferation signaling in human VS tumorigenesis may play a key role in molecular therapeutic targeting.
  • VS carry mutations of the NF2 gene encoding the tumor suppressor, merlin, which interacts with ErbB2 in Schwann cells, implicating ErbB receptors in VS tumorigenesis.
  • ErbB receptor family members are overexpressed or constitutively activated in many human tumors, and are effective therapeutic targets in some human cancers.
  • VS occur more frequently in women and are larger, more vascular, and demonstrate increased growth rates during pregnancy.
  • ER and PR may play a role in ErbB pathway activation and VS progression.
  • STUDY DESIGN: Quantitative real-time polymerase chain reaction (qRT-PCR) for ER and PR messenger RNA was performed using greater auricular and vestibular nerve controls (n = 8), sporadic VS (n = 23), and NF2-related VS (n = 16) tissues.
  • RESULTS: Reverse transcription of messenger RNA from control and tumor specimens followed by RT Q-PCR demonstrated differences in ER and PR gene expression between sporadic and NF2-related vs.
  • CONCLUSIONS: ER and PR expression in VS might have implications for development of a VS-specific drug delivery system using antihormone and ErbB pathway small molecule inhibitors, due to crosstalk between these receptors.
  • These signals may be critical for re-establishing ErbB-mediated cell density dependent growth inhibition.
  • [MeSH-major] Ear Neoplasms / metabolism. Neuroma, Acoustic / metabolism. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Vestibule, Labyrinth / metabolism

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  • (PMID = 18670322.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Grant] United States / BLRD VA / BX / I01 BX001205; United States / NIDCD NIH HHS / DC / T32 DC000028
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
  • [Other-IDs] NLM/ NIHMS438693; NLM/ PMC3570025
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94. Lee SH, Jang YH, Tae K, Park YW, Kang MJ, Kim KR, Park CW: Telomerase activity and cell proliferation index in cholesteatoma. Acta Otolaryngol; 2005 Jul;125(7):707-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Telomerase activity is detected in most malignant tumors and is also known to have a close relationship with cell proliferation.
  • We studied telomerase activity in cholesteatoma and its relationship with cellular proliferation and clinical findings.
  • MATERIAL AND METHODS: Cholesteatoma tissue was obtained from 40 patients during middle ear surgery.
  • Posterior auricular skin was used as a control.
  • RESULTS: Telomerase activity was positive in 21/40 cholesteatomas (52.5%), but absent in the control group.
  • [MeSH-major] Cell Proliferation. Cholesteatoma, Middle Ear / enzymology. Telomerase / metabolism

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  • (PMID = 16012031.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Ki-67 Antigen; EC 2.7.7.49 / Telomerase
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95. Clark RR, Soutar DS: Lymph node metastases from auricular squamous cell carcinoma. A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg; 2008 Oct;61(10):1140-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymph node metastases from auricular squamous cell carcinoma. A systematic review and meta-analysis.
  • INTRODUCTION: Squamous cell carcinoma arising on the auricle is believed to metastasise to the regional lymph nodes more frequently than comparable tumours at other sites.
  • Metastatic spread of these tumours is associated with a poor outcome but there is no clear consensus of opinion on how to identify patients at risk of metastatic spread and treat them.
  • RESULTS: The metastatic rate is 11.2% with spread to the parotid and upper deep cervical chain most common.
  • Depth of invasion, tumour size, degree of cellular differentiation and incomplete primary excision margins may be useful in identifying lesions most at risk of metastasising but there is insufficient evidence at present to allow targeted neck dissections.
  • [MeSH-major] Carcinoma, Squamous Cell / epidemiology. Ear Auricle. Ear Neoplasms / epidemiology

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  • (PMID = 18675609.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 62
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96. Vankalakunti M, Das A, Rao NK: Postauricular congenital alveolar rhabdomyosarcoma- a case report of an unusual entity. Diagn Pathol; 2006;1:37
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  • BACKGROUND: Congenital alveolar rhabdomyosarcoma is an extremely uncommon and invariably fatal tumor with the current therapy.
  • CASE PRESENTATION: We report a case of congenital alveolar rhabdomyosarcoma in an 18-month-old male who presented with a progressively increasing mass lesion in the left post-auricular region since birth.
  • Upon resecting the mass that was 10-cm in largest dimension, the gross, microscopic, and ultrastructural findings were consistent with congenital alveolar rhabdomyosarcoma.
  • CONCLUSION: The suspicion of alveolar subtype on histological grounds and proper evaluation of this tumor by immunostain and ultrastuctural examination is necessary.

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  • (PMID = 17044930.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1621081
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97. Ghosh SK, Bandyopadhyay D, Gupta S, Chatterjee G, Ghosh A: Rapidly growing extraocular sebaceous carcinoma occurring during pregnancy: a case report. Dermatol Online J; 2008;14(8):8
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  • Sebaceous carcinoma is a very rare, aggressive, malignant tumor derived from the adnexal epithelium of sebaceous glands.
  • It is traditionally classified into two groups: tumors arising from the ocular adnexa and those arising in extra-ocular sites.
  • Extraocular sebaceous carcinoma in the post-auricular region or in the external auditory canal is very rarely described in the literature.
  • A case of a rapidly growing sebaceous carcinoma of the pinna occurring in a pregnant woman is reported here for its rarity.
  • [MeSH-major] Adenocarcinoma, Sebaceous / pathology. Ear Neoplasms / pathology. Ear, External / pathology. Pregnancy Complications, Neoplastic / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Disease Progression. Female. Humans. Pregnancy

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  • (PMID = 19061568.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Crew KD, Capodice JL, Greenlee H, Brafman L, Fuentes D, Awad D, Yann Tsai W, Hershman DL: Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer. J Clin Oncol; 2010 Mar 1;28(7):1154-60
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  • TA included full body/auricular acupuncture and joint-specific point prescriptions, whereas SA involved superficial needle insertion at nonacupoint locations.
  • Results Of 51 women enrolled, 43 women were randomly assigned and 38 were evaluable.
  • Similar findings were seen for the WOMAC and M-SACRAH scores.
  • [MeSH-major] Acupuncture Therapy. Aromatase Inhibitors / adverse effects. Arthralgia / therapy. Breast Neoplasms / drug therapy
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Neoplasm Staging

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  • (PMID = 20100963.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aromatase Inhibitors
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99. Lo WC, Ting LL, Ko JY, Lou PJ, Yang TL, Chang YL, Wang CP: Malignancies of the ear in irradiated patients of nasopharyngeal carcinoma. Laryngoscope; 2008 Dec;118(12):2151-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignancies of the ear in irradiated patients of nasopharyngeal carcinoma.
  • OBJECTIVES/HYPOTHESIS: To report on the clinical profiles and treatment experiences of patients with second primary ear malignancy after treatment of nasopharyngeal carcinoma (NPC).
  • METHODS: A retrospective review of the clinical outcomes and pathology of 11 irradiated NPC patients who subsequently had second primary malignancies of the ear at a single institution.
  • RESULTS: Ten tumors were squamous cell carcinoma and one tumor was chondrosarcoma occurring within the radiation field of previous treatment for NPC.
  • The interval between previous radiotherapy and diagnosis of ear malignancy was 3 to 27 years with a median time of 17 years.
  • Six tumors were located in the external auditory canal, two in the middle ear cavity, two in the periauricular region and one in the mastoid cavity.
  • The 3-year disease-free and overall survival rates were 30.3% and 20%, respectively.
  • CONCLUSIONS: Postirradiated malignancy of the ear is extremely rare, but is one of the causes of death for NPC long-term survivors despite curative-intended treatment with surgery plus adjuvant radiotherapy is instituted.
  • [MeSH-major] Carcinoma, Squamous Cell / etiology. Chondrosarcoma / etiology. Ear Neoplasms / etiology. Nasopharyngeal Neoplasms / radiotherapy. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Radiotherapy Dosage. Radiotherapy, Adjuvant. Retrospective Studies

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  • (PMID = 18948828.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Hu J, Ye W, Zheng J, Zhu H, Zhang Z: The feasibility and significance of preservation of the lobular branch of the great auricular nerve in parotidectomy. Int J Oral Maxillofac Surg; 2010 Jul;39(7):684-9
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  • [Title] The feasibility and significance of preservation of the lobular branch of the great auricular nerve in parotidectomy.
  • This study was designed to evaluate the feasibility and significance of preserving the lobular branch of the great auricular nerve (GAN) during parotidectomy.
  • Ninety-three patients with benign tumour undergoing parotidectomy were separated randomly into three groups.
  • Thirty-one patients underwent a parotidectomy with the main trunk of GAN sacrificed (group A), 29 patients had the posterior-auricular branch preserved (group B), and 33 patients had the lobular branch preserved (group C).
  • These results demonstrate that preservation of the lobular branch of GAN is technically feasible during parotidectomy.
  • [MeSH-major] Parotid Gland / innervation. Parotid Neoplasms / surgery

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  • [Copyright] Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20413273.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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